1     M         0.995   1.008   1.071   1.215   1.227   1.308   1.061   1.078   1.168
2     L        -0.278  -0.249  -0.137  -0.531  -0.485  -0.292  -0.633  -0.590  -0.429
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     N        -0.420  -0.459  -0.745  -0.176  -0.240  -0.697  -0.407  -0.460  -0.834
5     R        -1.879  -1.823  -1.715  -1.746  -1.692  -1.485  -1.650  -1.586  -1.379
6     T        -2.338  -2.347  -2.054  -2.530  -2.535  -2.095  -1.876  -1.851  -1.503
7     I        -1.224  -1.354  -1.324  -1.099  -1.285  -1.220  -1.152  -1.295  -1.211
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    A        -1.070  -1.137  -1.284  -0.678  -0.790  -1.072  -0.972  -1.047  -1.170
29    K        -0.420  -0.529  -0.757  -0.275  -0.418  -0.761  -0.407  -0.554  -0.850
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    R        -0.537  -0.569  -0.779  -0.350  -0.425  -0.786  -0.562  -0.621  -0.879
34    T        -1.986  -1.939  -1.730  -2.015  -1.936  -1.649  -1.742  -1.680  -1.390
35    L        -1.224  -1.248  -1.310  -1.155  -1.224  -1.259  -1.152  -1.186  -1.196
36    A         0.206   0.055  -0.060   0.209   0.010  -0.147   0.176  -0.063  -0.289
37    T         0.206   0.210  -0.042   0.273   0.279  -0.114   0.176   0.179  -0.257
38    A        -1.986  -1.946  -1.733  -1.917  -1.879  -1.561  -1.742  -1.682  -1.392
39    A        -0.537  -0.569  -0.779  -0.508  -0.557  -0.863  -0.562  -0.622  -0.879
40    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    A        -2.005  -1.942  -1.737  -1.992  -1.899  -1.598  -1.763  -1.680  -1.396
42    E        -1.070  -1.251  -1.307  -0.849  -1.118  -1.243  -0.972  -1.177  -1.193
43    R        -2.671  -2.580  -2.328  -2.471  -2.383  -1.982  -1.989  -1.903  -1.583
44    T        -1.879  -1.649  -1.709  -1.837  -1.472  -1.646  -1.650  -1.422  -1.374
45    L        -0.737  -0.866  -0.816  -0.799  -0.981  -0.887  -0.859  -1.025  -0.931
46    P         0.995   1.008   1.071   1.143   1.157   1.245   1.061   1.078   1.168
47    K        -0.420  -0.591  -0.768  -0.321  -0.558  -0.887  -0.407  -0.634  -0.865
48    K         0.270   0.236  -0.027   0.336   0.304  -0.102   0.271   0.219  -0.232
49    Y         0.995   1.008   1.071   1.210   1.226   1.304   1.061   1.078   1.168
50    G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
51    G         0.270   0.236  -0.027   0.201   0.165  -0.215   0.271   0.219  -0.232
52    R        -0.338  -0.295  -0.140  -0.584  -0.519  -0.267  -0.746  -0.675  -0.434
53    F         0.270   0.306  -0.019   0.589   0.631   0.147   0.271   0.321  -0.218
54    T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
55    V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
56    T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
57    L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
58    I         0.995   1.008   1.071   0.924   0.944   1.053   1.061   1.078   1.168
59    P         0.995   1.008   1.071   1.143   1.157   1.245   1.061   1.078   1.168
60    G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
61    D         0.995   1.008   1.071   1.062   1.075   1.174   1.061   1.078   1.168
62    G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
63    V        -0.879  -0.781  -0.813  -1.178  -1.063  -1.048  -1.085  -0.988  -0.929
64    G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
65    K        -1.671  -1.733  -1.712  -1.458  -1.582  -1.531  -1.424  -1.482  -1.375
66    E         0.995   1.008   1.071   1.030   1.050   1.146   1.061   1.078   1.168
67    I        -0.737  -0.793  -0.805  -0.869  -0.956  -0.991  -0.859  -0.924  -0.917
68    T        -0.420  -0.591  -0.768  -0.292  -0.539  -0.855  -0.407  -0.634  -0.865
69    D        -0.420  -0.591  -0.768  -0.197  -0.440  -0.738  -0.407  -0.634  -0.865
70    S        -0.087  -0.138  -0.115  -0.176  -0.279  -0.294  -0.294  -0.390  -0.389
71    V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
72    R        -1.546  -1.496  -1.333  -1.685  -1.595  -1.353  -1.537  -1.458  -1.221
73    T        -1.671  -1.539  -1.682  -1.444  -1.282  -1.486  -1.424  -1.288  -1.349
74    I         0.270   0.159  -0.035   0.270   0.119  -0.203   0.271   0.101  -0.245
75    F         0.995   1.008   1.071   1.145   1.157   1.247   1.061   1.078   1.168
76    E        -0.879  -0.734  -0.803  -1.032  -0.828  -0.881  -1.085  -0.911  -0.914
77    A        -1.879  -1.648  -1.710  -1.852  -1.587  -1.564  -1.650  -1.446  -1.375
78    E        -1.879  -1.919  -1.734  -1.747  -1.831  -1.584  -1.650  -1.654  -1.393
79    N         0.270   0.236  -0.027   0.420   0.378  -0.036   0.271   0.219  -0.232
80    I        -0.278  -0.219  -0.123  -0.631  -0.526  -0.379  -0.633  -0.535  -0.403
81    P         0.995   1.008   1.071   1.143   1.157   1.245   1.061   1.078   1.168
82    I         0.270   0.272  -0.021   0.270   0.274  -0.177   0.271   0.271  -0.221
83    D        -0.737  -0.803  -0.803  -0.691  -0.790  -0.827  -0.859  -0.930  -0.914
84    W         0.270   0.201  -0.026   0.695   0.602   0.220   0.271   0.166  -0.230
85    E         0.995   1.008   1.071   1.030   1.050   1.146   1.061   1.078   1.168
86    T        -1.879  -1.927  -1.732  -1.838  -1.883  -1.569  -1.650  -1.665  -1.392
87    I        -0.338  -0.301  -0.142  -0.756  -0.692  -0.416  -0.746  -0.686  -0.437
88    N        -1.005  -0.993  -0.844  -1.086  -1.082  -0.870  -1.198  -1.178  -0.964
89    I        -0.278  -0.219  -0.123  -0.631  -0.526  -0.379  -0.633  -0.535  -0.403
90    K        -0.737  -0.753  -0.800  -0.750  -0.800  -0.878  -0.859  -0.895  -0.910
91    Q        -0.420  -0.395  -0.745  -0.401  -0.367  -0.828  -0.407  -0.374  -0.834
92    T        -1.879  -1.820  -1.714  -1.925  -1.797  -1.637  -1.650  -1.565  -1.377
93    D        -1.338  -1.423  -1.320  -1.266  -1.389  -1.254  -1.311  -1.384  -1.208
94    H        -2.671  -2.600  -2.334  -2.403  -2.315  -1.960  -1.989  -1.916  -1.586
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   K        -2.671  -2.583  -2.329  -2.733  -2.610  -2.230  -1.989  -1.904  -1.583
101   E        -1.879  -1.729  -1.715  -1.662  -1.501  -1.402  -1.650  -1.515  -1.379
102   G        -1.338  -1.296  -1.316  -1.498  -1.484  -1.422  -1.311  -1.284  -1.205
103   V        -1.070  -1.251  -1.307  -0.935  -1.187  -1.256  -0.972  -1.177  -1.193
104   Y        -2.671  -2.567  -2.325  -2.189  -2.058  -1.762  -1.989  -1.893  -1.581
105   E        -0.737  -0.680  -0.798  -0.641  -0.599  -0.724  -0.859  -0.819  -0.909
106   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
107   V        -0.087  -0.138  -0.115  -0.275  -0.372  -0.364  -0.294  -0.390  -0.389
108   E        -1.070  -1.251  -1.307  -0.827  -1.097  -1.199  -0.972  -1.177  -1.193
109   S         0.995   1.008   1.071   1.018   1.038   1.136   1.061   1.078   1.168
110   L         0.270   0.236  -0.027   0.233   0.198  -0.215   0.271   0.219  -0.232
111   K        -0.420  -0.560  -0.764  -0.276  -0.458  -0.774  -0.407  -0.594  -0.860
112   R         0.995   1.008   1.071   1.092   1.104   1.201   1.061   1.078   1.168
113   N         0.995   1.008   1.071   1.058   1.077   1.171   1.061   1.078   1.168
114   K         0.995   1.008   1.071   0.972   1.000   1.095   1.061   1.078   1.168
115   I        -0.737  -0.811  -0.801  -0.900  -1.013  -1.027  -0.859  -0.943  -0.909
116   G         0.270   0.236  -0.027   0.183   0.145  -0.262   0.271   0.219  -0.232
117   L         0.270   0.236  -0.027   0.233   0.198  -0.215   0.271   0.219  -0.232
118   K         0.995   1.008   1.071   0.972   1.000   1.095   1.061   1.078   1.168
119   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
120   L         0.270   0.306  -0.019   0.266   0.317  -0.182   0.271   0.321  -0.218
121   W        -0.278  -0.219  -0.123  -0.436  -0.348  -0.179  -0.633  -0.535  -0.403
122   H        -0.737  -0.659  -0.775  -0.455  -0.335  -0.538  -0.859  -0.729  -0.874
123   T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
124   P        -0.087  -0.009  -0.100  -0.017   0.100  -0.107  -0.294  -0.169  -0.360
125   A        -1.879  -1.919  -1.734  -1.943  -1.997  -1.714  -1.650  -1.654  -1.393
126   D        -1.546  -1.535  -1.343  -1.677  -1.638  -1.367  -1.537  -1.502  -1.230
127   Q        -1.879  -1.812  -1.719  -1.759  -1.675  -1.543  -1.650  -1.570  -1.382
128   T        -1.879  -1.890  -1.726  -1.846  -1.865  -1.640  -1.650  -1.632  -1.387
129   G        -0.420  -0.304  -0.735  -0.441  -0.286  -0.901  -0.407  -0.259  -0.821
130   H         0.995   1.008   1.071   1.202   1.216   1.297   1.061   1.078   1.168
131   G        -1.546  -1.535  -1.343  -1.754  -1.704  -1.378  -1.537  -1.502  -1.230
132   S         0.995   1.008   1.071   1.018   1.038   1.136   1.061   1.078   1.168
133   L        -0.338  -0.276  -0.132  -0.608  -0.465  -0.247  -0.746  -0.639  -0.418
134   N         0.995   1.008   1.071   1.058   1.077   1.171   1.061   1.078   1.168
135   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
136   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
137   L         0.270   0.159  -0.035   0.276   0.148  -0.110   0.271   0.101  -0.245
138   R         0.995   1.008   1.071   1.092   1.104   1.201   1.061   1.078   1.168
139   K        -0.420  -0.560  -0.764  -0.253  -0.429  -0.721  -0.407  -0.594  -0.860
140   Q        -0.278  -0.219  -0.123  -0.380  -0.291  -0.145  -0.633  -0.535  -0.403
141   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
142   D         0.995   1.008   1.071   1.062   1.075   1.174   1.061   1.078   1.168
143   I         0.270   0.272  -0.021   0.315   0.320  -0.058   0.271   0.271  -0.221
144   Y        -0.278  -0.241  -0.134  -0.250  -0.198  -0.065  -0.633  -0.574  -0.423
145   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
146   N        -0.737  -0.658  -0.789  -0.679  -0.553  -0.736  -0.859  -0.738  -0.894
147   V        -0.879  -0.917  -0.820  -1.203  -1.237  -1.072  -1.085  -1.103  -0.935
148   A        -0.879  -0.917  -0.820  -1.169  -1.201  -1.023  -1.085  -1.103  -0.935
149   L         0.270   0.272  -0.021   0.265   0.277  -0.117   0.271   0.271  -0.221
150   F        -0.879  -0.917  -0.820  -1.022  -1.073  -0.917  -1.085  -1.103  -0.935
151   K         0.995   1.008   1.071   0.972   1.000   1.095   1.061   1.078   1.168
152   S        -0.278  -0.219  -0.123  -0.447  -0.347  -0.218  -0.633  -0.535  -0.403
153   L        -0.737  -0.773  -0.805  -0.895  -0.972  -1.040  -0.859  -0.913  -0.918
154   K         0.270   0.306  -0.019   0.498   0.542   0.031   0.271   0.321  -0.218
155   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
156   V        -0.420  -0.591  -0.768  -0.360  -0.597  -0.874  -0.407  -0.634  -0.865
157   K        -0.087  -0.160  -0.124  -0.124  -0.238  -0.187  -0.294  -0.428  -0.404
158   T        -0.087   0.080  -0.061  -0.217   0.058  -0.224  -0.294  -0.023  -0.292
159   R        -0.420  -0.304  -0.735  -0.198  -0.054  -0.727  -0.407  -0.259  -0.821
160   I        -1.546  -1.464  -1.338  -1.622  -1.506  -1.257  -1.537  -1.457  -1.226
161   P        -1.879  -1.766  -1.718  -1.702  -1.574  -1.496  -1.650  -1.541  -1.381
162   D        -1.087  -1.062  -0.852  -1.370  -1.320  -0.979  -1.311  -1.270  -0.973
163   I        -0.278  -0.296  -0.144  -0.626  -0.680  -0.420  -0.633  -0.675  -0.440
164   D         0.995   1.008   1.071   1.062   1.075   1.174   1.061   1.078   1.168
165   L        -1.087  -1.027  -0.849  -1.209  -1.141  -0.844  -1.311  -1.228  -0.970
166   I        -1.338  -1.346  -1.320  -1.409  -1.388  -1.330  -1.311  -1.300  -1.208
167   V        -1.087  -1.037  -0.843  -1.507  -1.419  -1.104  -1.311  -1.240  -0.962
168   I        -0.087   0.080  -0.061  -0.265   0.003  -0.253  -0.294  -0.023  -0.292
169   R         0.995   1.008   1.071   1.092   1.104   1.201   1.061   1.078   1.168
170   E         0.995   1.008   1.071   1.030   1.050   1.146   1.061   1.078   1.168
171   N         0.995   1.008   1.071   1.058   1.077   1.171   1.061   1.078   1.168
172   T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
173   E         0.995   1.008   1.071   1.030   1.050   1.146   1.061   1.078   1.168
174   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
175   E         0.995   1.008   1.071   1.030   1.050   1.146   1.061   1.078   1.168
176   F         0.270   0.306  -0.019   0.589   0.631   0.147   0.271   0.321  -0.218
177   S         0.995   1.008   1.071   1.018   1.038   1.136   1.061   1.078   1.168
178   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
179   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
180   E         0.995   1.008   1.071   1.030   1.050   1.146   1.061   1.078   1.168
181   H         0.995   1.008   1.071   1.215   1.226   1.308   1.061   1.078   1.168
182   E        -0.879  -0.864  -0.815  -0.852  -0.821  -0.755  -1.085  -1.044  -0.929
183   S         0.270   0.236  -0.027   0.398   0.359  -0.021   0.271   0.219  -0.232
184   V        -0.087   0.080  -0.061  -0.180   0.061  -0.134  -0.294  -0.023  -0.292
185   P         0.270   0.159  -0.035   0.511   0.360   0.035   0.271   0.101  -0.245
186   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
187   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
188   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
189   E         0.995   1.008   1.071   1.030   1.050   1.146   1.061   1.078   1.168
190   S         0.995   1.008   1.071   1.018   1.038   1.136   1.061   1.078   1.168
191   L         0.270   0.236  -0.027   0.233   0.198  -0.215   0.271   0.219  -0.232
192   K         0.995   1.008   1.071   0.972   1.000   1.095   1.061   1.078   1.168
193   V        -0.087  -0.084  -0.115  -0.265  -0.266  -0.359  -0.294  -0.295  -0.387
194   M        -0.338  -0.276  -0.132  -0.528  -0.458  -0.218  -0.746  -0.639  -0.418
195   T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
196   R        -0.737  -0.808  -0.804  -0.677  -0.796  -0.827  -0.859  -0.946  -0.916
197   P        -1.879  -1.840  -1.715  -1.727  -1.671  -1.446  -1.650  -1.583  -1.378
198   K         0.995   1.008   1.071   0.972   1.000   1.095   1.061   1.078   1.168
199   T         0.270   0.306  -0.019   0.377   0.425  -0.063   0.271   0.321  -0.218
200   E         0.270   0.201  -0.026   0.385   0.298  -0.075   0.271   0.166  -0.230
201   R         0.995   1.008   1.071   1.092   1.104   1.201   1.061   1.078   1.168
202   I         0.995   1.008   1.071   0.924   0.944   1.053   1.061   1.078   1.168
203   A         0.270   0.159  -0.035   0.257   0.111  -0.189   0.271   0.101  -0.245
204   R        -0.879  -0.893  -0.815  -0.933  -0.933  -0.790  -1.085  -1.078  -0.931
205   F         0.995   1.008   1.071   1.145   1.157   1.247   1.061   1.078   1.168
206   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
207   F         0.995   1.008   1.071   1.145   1.157   1.247   1.061   1.078   1.168
208   D         0.270   0.159  -0.035   0.449   0.304   0.021   0.271   0.101  -0.245
209   F         0.995   1.008   1.071   1.145   1.157   1.247   1.061   1.078   1.168
210   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
211   K        -0.278  -0.217  -0.128  -0.626  -0.511  -0.378  -0.633  -0.531  -0.411
212   K        -0.420  -0.591  -0.768  -0.285  -0.516  -0.801  -0.407  -0.634  -0.865
213   Y        -0.087  -0.063  -0.093  -0.037  -0.005  -0.069  -0.294  -0.261  -0.349
214   N        -0.420  -0.591  -0.768  -0.209  -0.447  -0.760  -0.407  -0.634  -0.865
215   R         0.995   1.008   1.071   1.092   1.104   1.201   1.061   1.078   1.168
216   K         0.270   0.236  -0.027   0.363   0.333  -0.029   0.271   0.219  -0.232
217   S        -1.005  -0.936  -0.830  -1.223  -1.112  -0.980  -1.198  -1.112  -0.947
218   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
219   T        -0.087  -0.011  -0.084  -0.063   0.042  -0.055  -0.294  -0.171  -0.332
220   A        -0.087  -0.176  -0.121  -0.155  -0.286  -0.172  -0.294  -0.456  -0.400
221   V        -0.278  -0.219  -0.123  -0.626  -0.521  -0.376  -0.633  -0.535  -0.403
222   H         0.995   1.008   1.071   1.215   1.226   1.308   1.061   1.078   1.168
223   K         0.995   1.008   1.071   0.972   1.000   1.095   1.061   1.078   1.168
224   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
225   N         0.995   1.008   1.071   1.058   1.077   1.171   1.061   1.078   1.168
226   I         0.995   1.008   1.071   0.924   0.944   1.053   1.061   1.078   1.168
227   M         0.995   1.008   1.071   1.215   1.227   1.308   1.061   1.078   1.168
228   K         0.995   1.008   1.071   0.972   1.000   1.095   1.061   1.078   1.168
229   L         0.270   0.272  -0.021   0.276   0.288  -0.090   0.271   0.271  -0.221
230   G        -0.278  -0.299  -0.144  -0.707  -0.761  -0.482  -0.633  -0.682  -0.440
231   D         0.995   1.008   1.071   1.062   1.075   1.174   1.061   1.078   1.168
232   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
233   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
234   F         0.995   1.008   1.071   1.145   1.157   1.247   1.061   1.078   1.168
235   R         0.995   1.008   1.071   1.092   1.104   1.201   1.061   1.078   1.168
236   N        -1.671  -1.613  -1.704  -1.405  -1.374  -1.511  -1.424  -1.369  -1.368
237   I         0.270   0.306  -0.019   0.344   0.392  -0.108   0.271   0.321  -0.218
238   I        -1.338  -1.382  -1.324  -1.290  -1.348  -1.211  -1.311  -1.362  -1.213
239   T        -1.546  -1.553  -1.343  -1.602  -1.591  -1.261  -1.537  -1.522  -1.231
240   E        -0.879  -0.914  -0.816  -0.950  -0.980  -0.818  -1.085  -1.097  -0.931
241   I        -0.879  -0.917  -0.820  -1.181  -1.222  -1.063  -1.085  -1.103  -0.935
242   G        -0.737  -0.835  -0.816  -0.951  -1.128  -1.063  -0.859  -0.999  -0.931
243   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   K        -1.546  -1.493  -1.329  -1.558  -1.503  -1.269  -1.537  -1.463  -1.218
245   E        -0.879  -0.893  -0.815  -1.001  -1.018  -0.912  -1.085  -1.078  -0.931
246   Y         0.270   0.159  -0.035   0.589   0.443   0.120   0.271   0.101  -0.245
247   P        -0.420  -0.365  -0.741  -0.137  -0.075  -0.676  -0.407  -0.344  -0.829
248   D        -2.005  -2.005  -1.736  -2.060  -2.026  -1.634  -1.763  -1.731  -1.395
249   I        -0.087  -0.083  -0.115  -0.273  -0.272  -0.373  -0.294  -0.294  -0.389
250   D        -2.005  -1.928  -1.730  -1.925  -1.818  -1.554  -1.763  -1.680  -1.391
251   V        -1.671  -1.819  -1.719  -1.417  -1.597  -1.418  -1.424  -1.559  -1.381
252   S        -1.546  -1.533  -1.339  -1.674  -1.656  -1.382  -1.537  -1.504  -1.228
253   S        -0.737  -0.611  -0.791  -0.683  -0.529  -0.787  -0.859  -0.709  -0.897
254   I        -1.087  -1.071  -0.854  -1.360  -1.308  -0.953  -1.311  -1.282  -0.976
255   I         0.995   1.008   1.071   0.924   0.944   1.053   1.061   1.078   1.168
256   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
257   D         0.995   1.008   1.071   1.062   1.075   1.174   1.061   1.078   1.168
258   N         0.995   1.008   1.071   1.058   1.077   1.171   1.061   1.078   1.168
259   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
260   S         0.995   1.008   1.071   1.018   1.038   1.136   1.061   1.078   1.168
261   M         0.995   1.008   1.071   1.215   1.227   1.308   1.061   1.078   1.168
262   Q         0.995   1.008   1.071   1.193   1.201   1.289   1.061   1.078   1.168
263   A         0.270   0.159  -0.035   0.304   0.173  -0.061   0.271   0.101  -0.245
264   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
265   A        -0.278  -0.299  -0.144  -0.589  -0.635  -0.365  -0.633  -0.682  -0.440
266   K        -0.420  -0.522  -0.758  -0.231  -0.353  -0.663  -0.407  -0.542  -0.852
267   P         0.995   1.008   1.071   1.143   1.157   1.245   1.061   1.078   1.168
268   H        -0.278  -0.219  -0.123  -0.228  -0.147  -0.018  -0.633  -0.535  -0.403
269   Q         0.995   1.008   1.071   1.193   1.201   1.289   1.061   1.078   1.168
270   F         0.995   1.008   1.071   1.145   1.157   1.247   1.061   1.078   1.168
271   D         0.995   1.008   1.071   1.062   1.075   1.174   1.061   1.078   1.168
272   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
273   L        -0.087  -0.144  -0.125  -0.201  -0.284  -0.238  -0.294  -0.400  -0.406
274   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
275   T        -0.087  -0.176  -0.121  -0.095  -0.240  -0.155  -0.294  -0.456  -0.400
276   P         0.995   1.008   1.071   1.143   1.157   1.245   1.061   1.078   1.168
277   S        -0.087  -0.063  -0.093  -0.099  -0.066  -0.159  -0.294  -0.261  -0.349
278   M        -0.087  -0.063  -0.093  -0.201  -0.162  -0.197  -0.294  -0.261  -0.349
279   Y         0.995   1.008   1.071   1.210   1.226   1.304   1.061   1.078   1.168
280   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
281   T        -0.879  -0.915  -0.809  -1.057  -1.101  -0.949  -1.085  -1.099  -0.924
282   I         0.995   1.008   1.071   0.924   0.944   1.053   1.061   1.078   1.168
283   L         0.270   0.272  -0.021   0.233   0.244  -0.203   0.271   0.271  -0.221
284   G        -0.278  -0.219  -0.123  -0.577  -0.467  -0.343  -0.633  -0.535  -0.403
285   N         0.995   1.008   1.071   1.058   1.077   1.171   1.061   1.078   1.168
286   I         0.995   1.008   1.071   0.924   0.944   1.053   1.061   1.078   1.168
287   G         0.270   0.159  -0.035   0.183   0.036  -0.277   0.271   0.101  -0.245
288   A        -0.087  -0.056  -0.107  -0.253  -0.207  -0.306  -0.294  -0.248  -0.373
289   A         0.270   0.236  -0.027   0.234   0.191  -0.236   0.271   0.219  -0.232
290   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
291   I        -0.278  -0.299  -0.144  -0.626  -0.688  -0.420  -0.633  -0.682  -0.440
292   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
293   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
294   P         0.995   1.008   1.071   1.143   1.157   1.245   1.061   1.078   1.168
295   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
296   L        -0.087  -0.176  -0.121  -0.303  -0.466  -0.402  -0.294  -0.456  -0.400
297   V         0.270   0.201  -0.026   0.256   0.169  -0.193   0.271   0.166  -0.230
298   A        -0.087  -0.063  -0.093  -0.054  -0.027  -0.150  -0.294  -0.261  -0.349
299   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
300   A        -0.420  -0.560  -0.764  -0.336  -0.515  -0.798  -0.407  -0.594  -0.860
301   N         0.270   0.272  -0.021   0.449   0.452   0.049   0.271   0.271  -0.221
302   F        -1.070  -1.198  -1.293  -0.691  -0.879  -1.055  -0.972  -1.117  -1.179
303   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
304   R         0.270   0.236  -0.027   0.451   0.402  -0.017   0.271   0.219  -0.232
305   D        -0.278  -0.291  -0.143  -0.449  -0.491  -0.252  -0.633  -0.668  -0.440
306   Y        -0.737  -0.840  -0.807  -0.500  -0.670  -0.674  -0.859  -0.986  -0.920
307   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
308   V         0.270   0.201  -0.026   0.251   0.163  -0.209   0.271   0.166  -0.230
309   F         0.995   1.008   1.071   1.145   1.157   1.247   1.061   1.078   1.168
310   E         0.995   1.008   1.071   1.030   1.050   1.146   1.061   1.078   1.168
311   P         0.995   1.008   1.071   1.143   1.157   1.245   1.061   1.078   1.168
312   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
313   S        -0.278  -0.219  -0.123  -0.227  -0.130  -0.036  -0.633  -0.535  -0.403
314   R         0.270   0.272  -0.021   0.479   0.475   0.068   0.271   0.271  -0.221
315   H         0.995   1.008   1.071   1.215   1.226   1.308   1.061   1.078   1.168
316   V         0.995   1.008   1.071   0.908   0.930   1.039   1.061   1.078   1.168
317   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
318   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
319   D         0.270   0.201  -0.026   0.424   0.330  -0.031   0.271   0.166  -0.230
320   I         0.995   1.008   1.071   0.924   0.944   1.053   1.061   1.078   1.168
321   K        -0.420  -0.591  -0.768  -0.269  -0.490  -0.764  -0.407  -0.634  -0.865
322   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
323   Q        -1.087  -1.059  -0.847  -1.175  -1.153  -0.828  -1.311  -1.266  -0.968
324   N        -0.737  -0.866  -0.816  -0.753  -0.977  -0.928  -0.859  -1.025  -0.931
325   V        -1.879  -1.869  -1.730  -1.859  -1.836  -1.596  -1.650  -1.624  -1.390
326   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
327   N         0.995   1.008   1.071   1.058   1.077   1.171   1.061   1.078   1.168
328   P         0.995   1.008   1.071   1.143   1.157   1.245   1.061   1.078   1.168
329   T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
330   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
331   M        -0.420  -0.591  -0.768  -0.094  -0.357  -0.740  -0.407  -0.634  -0.865
332   I         0.270   0.159  -0.035   0.266   0.116  -0.212   0.271   0.101  -0.245
333   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
334   S         0.995   1.008   1.071   1.018   1.038   1.136   1.061   1.078   1.168
335   S        -0.737  -0.803  -0.803  -0.811  -0.916  -0.984  -0.859  -0.930  -0.914
336   T        -0.879  -0.876  -0.812  -1.032  -0.986  -0.834  -1.085  -1.052  -0.925
337   L        -0.338  -0.306  -0.144  -0.555  -0.506  -0.244  -0.746  -0.695  -0.440
338   M        -0.278  -0.269  -0.140  -0.377  -0.388  -0.223  -0.633  -0.626  -0.434
339   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
340   N        -0.420  -0.395  -0.745  -0.140  -0.116  -0.616  -0.407  -0.374  -0.834
341   H         0.995   1.008   1.071   1.215   1.226   1.308   1.061   1.078   1.168
342   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
343   G         0.270   0.236  -0.027   0.207   0.171  -0.199   0.271   0.219  -0.232
344   L         0.995   1.008   1.071   0.885   0.912   1.018   1.061   1.078   1.168
345   N        -1.338  -1.418  -1.325  -1.256  -1.401  -1.271  -1.311  -1.393  -1.214
346   E        -0.737  -0.611  -0.791  -0.709  -0.547  -0.841  -0.859  -0.709  -0.897
347   Y        -1.420  -1.415  -1.320  -1.157  -1.153  -1.028  -1.424  -1.397  -1.209
348   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
349   T        -1.070  -1.143  -1.290  -0.827  -0.944  -1.212  -0.972  -1.055  -1.176
350   R        -1.338  -1.307  -1.307  -1.304  -1.237  -1.324  -1.311  -1.244  -1.194
351   I         0.995   1.008   1.071   0.924   0.944   1.053   1.061   1.078   1.168
352   S        -0.420  -0.491  -0.748  -0.262  -0.359  -0.786  -0.407  -0.501  -0.839
353   K        -0.420  -0.591  -0.768  -0.308  -0.541  -0.856  -0.407  -0.634  -0.865
354   A         0.995   1.008   1.071   0.898   0.918   1.030   1.061   1.078   1.168
355   V        -0.087  -0.128  -0.124  -0.195  -0.278  -0.325  -0.294  -0.372  -0.404
356   H        -0.087  -0.063  -0.093   0.109   0.136   0.046  -0.294  -0.261  -0.349
357   E        -0.420  -0.459  -0.745  -0.204  -0.265  -0.713  -0.407  -0.460  -0.834
358   T         0.270   0.306  -0.019   0.267   0.317  -0.153   0.271   0.321  -0.218
359   I         0.270   0.236  -0.027   0.266   0.225  -0.198   0.271   0.219  -0.232
360   A        -0.737  -0.735  -0.785  -0.844  -0.827  -0.904  -0.859  -0.838  -0.889
361   E        -0.420  -0.529  -0.757  -0.230  -0.374  -0.745  -0.407  -0.554  -0.850
362   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
363   K        -1.005  -0.898  -0.821  -1.092  -0.926  -0.808  -1.198  -1.057  -0.936
364   H        -1.070  -1.002  -1.269  -0.937  -0.857  -1.211  -0.972  -0.895  -1.154
365   T        -0.879  -0.888  -0.814  -0.982  -0.987  -0.888  -1.085  -1.071  -0.928
366   T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
367   R        -1.420  -1.338  -1.310  -1.434  -1.319  -1.252  -1.424  -1.334  -1.200
368   D         0.995   1.008   1.071   1.062   1.075   1.174   1.061   1.078   1.168
369   I        -0.737  -0.866  -0.816  -0.834  -1.032  -0.931  -0.859  -1.025  -0.931
370   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
371   G         0.995   1.008   1.071   0.839   0.863   0.979   1.061   1.078   1.168
372   S        -1.671  -1.589  -1.701  -1.478  -1.376  -1.586  -1.424  -1.343  -1.365
373   S        -0.278  -0.229  -0.133  -0.589  -0.508  -0.351  -0.633  -0.552  -0.421
374   S        -0.087  -0.032  -0.097  -0.145  -0.060  -0.208  -0.294  -0.208  -0.356
375   T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
376   T        -1.671  -1.734  -1.713  -1.462  -1.574  -1.559  -1.424  -1.484  -1.376
377   D        -0.087  -0.104  -0.118  -0.112  -0.147  -0.206  -0.294  -0.330  -0.393
378   F         0.995   1.008   1.071   1.145   1.157   1.247   1.061   1.078   1.168
379   T         0.995   1.008   1.071   0.995   1.015   1.115   1.061   1.078   1.168
380   N        -2.338  -2.316  -2.056  -2.023  -1.986  -1.615  -1.876  -1.833  -1.504
381   E         0.270   0.306  -0.019   0.262   0.310  -0.148   0.271   0.321  -0.218
382   I        -0.087  -0.033  -0.107  -0.265  -0.179  -0.343  -0.294  -0.209  -0.373
383   I        -0.737  -0.700  -0.804  -0.895  -0.900  -1.035  -0.859  -0.855  -0.915
384   N        -1.879  -1.839  -1.715  -1.801  -1.749  -1.592  -1.650  -1.600  -1.379
385   K        -0.737  -0.854  -0.810  -0.747  -0.920  -0.857  -0.859  -1.006  -0.923
386   L        -0.087  -0.176  -0.121  -0.201  -0.333  -0.234  -0.294  -0.456  -0.400
387   S        -2.671  -2.480  -2.327  -2.471  -2.192  -2.013  -1.989  -1.829  -1.582
388   T        -1.567  -1.518  -1.338  -1.683  -1.614  -1.350  -1.541  -1.479  -1.224
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   M         0.032   0.111  -0.065  -0.023   0.082  -0.153  -0.095   0.027  -0.298
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P28834
Output conservation file - output/P28834
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
