1     M         1.939   1.962   2.073   2.188   2.221   2.397   2.179   2.216   2.407
2     S         0.599   0.490   0.374   0.516   0.366   0.209   0.588   0.420   0.221
3     S        -0.747  -0.733  -0.748  -0.870  -0.846  -0.880  -0.699  -0.680  -0.680
4     S         0.208   0.269   0.206  -0.097  -0.013  -0.133  -0.015   0.078  -0.048
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     F        -0.386  -0.426  -0.386  -0.311  -0.356  -0.302  -0.539  -0.578  -0.517
8     E        -0.901  -0.881  -0.818  -1.001  -0.971  -0.873  -0.881  -0.855  -0.760
9     E         0.300   0.353   0.263   0.236   0.317   0.180   0.098   0.191   0.028
10    V        -0.270  -0.251  -0.305  -0.297  -0.278  -0.347  -0.392  -0.384  -0.423
11    I         0.165   0.176   0.189  -0.059  -0.046  -0.013  -0.147  -0.130  -0.101
12    N        -1.532  -1.517  -1.446  -1.457  -1.418  -1.321  -1.126  -1.110  -1.005
13    K        -0.466  -0.432  -0.403  -0.794  -0.753  -0.698  -0.636  -0.605  -0.543
14    I        -0.032  -0.020   0.079  -0.268  -0.241  -0.100  -0.392  -0.375  -0.247
15    I         0.677   0.693   0.807   0.309   0.328   0.498   0.220   0.242   0.402
16    N        -1.532  -1.549  -1.450  -1.274  -1.277  -1.148  -1.126  -1.133  -1.007
17    D        -0.270  -0.338  -0.321  -0.378  -0.475  -0.470  -0.392  -0.465  -0.437
18    S         0.734   0.747   0.830   0.372   0.388   0.511   0.343   0.358   0.453
19    P         1.939   1.962   2.073   2.079   2.113   2.286   2.179   2.216   2.407
20    P         1.253   1.341   1.138   1.498   1.609   1.367   1.322   1.464   1.083
21    G         0.599   0.613   0.395   0.765   0.789   0.484   0.588   0.610   0.255
22    E         1.939   1.962   2.073   1.833   1.859   2.038   2.179   2.216   2.407
23    L         0.599   0.499   0.376   0.688   0.553   0.360   0.588   0.433   0.224
24    R        -1.216  -1.143  -1.139  -1.321  -1.222  -1.205  -1.004  -0.939  -0.888
25    E        -0.386  -0.324  -0.343  -0.376  -0.259  -0.302  -0.539  -0.449  -0.463
26    V         1.192   1.244   1.097   1.197   1.261   1.057   1.219   1.305   1.005
27    Y        -0.026  -0.028   0.078  -0.290  -0.310  -0.159  -0.379  -0.386  -0.249
28    D        -0.386  -0.456  -0.373  -0.322  -0.407  -0.303  -0.539  -0.612  -0.505
29    D        -0.016  -0.006  -0.193   0.097   0.117  -0.186  -0.024  -0.008  -0.261
30    L         0.734   0.718   0.820   0.447   0.403   0.540   0.343   0.297   0.431
31    I        -0.782  -0.825  -0.781  -0.907  -0.941  -0.869  -0.759  -0.790  -0.718
32    K        -1.216  -1.225  -1.144  -1.094  -1.109  -1.015  -1.004  -1.004  -0.892
33    I         0.165   0.174   0.191  -0.065  -0.052  -0.018  -0.147  -0.136  -0.102
34    T        -1.097  -1.102  -1.090  -0.856  -0.873  -0.882  -0.881  -0.884  -0.839
35    S        -0.782  -0.792  -0.758  -0.943  -0.960  -0.902  -0.759  -0.768  -0.699
36    E        -0.032   0.013   0.105  -0.409  -0.349  -0.213  -0.392  -0.333  -0.212
37    N        -0.782  -0.824  -0.778  -0.712  -0.765  -0.696  -0.759  -0.797  -0.720
38    S         0.599   0.490   0.374   0.530   0.382   0.234   0.588   0.420   0.221
39    K        -0.782  -0.827  -0.785  -0.871  -0.944  -0.895  -0.759  -0.798  -0.726
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -         0.018  -0.003   0.099  -0.421  -0.442  -0.301  -0.328  -0.353  -0.220
42    N        -0.782  -0.795  -0.773  -0.869  -0.863  -0.820  -0.759  -0.768  -0.714
43    T        -0.270  -0.311  -0.332  -0.175  -0.264  -0.293  -0.392  -0.453  -0.457
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    I         0.199   0.193   0.183   0.026   0.010  -0.010  -0.059  -0.082  -0.095
48    L        -1.604  -1.593  -1.483  -1.467  -1.437  -1.297  -1.178  -1.163  -1.031
49    D        -0.386  -0.430  -0.374  -0.404  -0.460  -0.388  -0.539  -0.585  -0.507
50    A        -0.585  -0.656  -0.699  -0.358  -0.461  -0.576  -0.514  -0.595  -0.625
51    I        -0.016  -0.116  -0.227   0.082  -0.054  -0.221  -0.024  -0.158  -0.306
52    E        -0.782  -0.802  -0.773  -0.659  -0.699  -0.617  -0.759  -0.778  -0.714
53    N        -0.901  -0.924  -0.819  -1.012  -1.040  -0.882  -0.881  -0.893  -0.760
54    Y         0.599   0.603   0.395   0.808   0.817   0.529   0.588   0.594   0.255
55    N        -0.270  -0.320  -0.321  -0.269  -0.315  -0.323  -0.392  -0.446  -0.442
56    V        -0.782  -0.716  -0.753  -0.801  -0.700  -0.748  -0.759  -0.677  -0.689
57    Q        -0.270  -0.266  -0.313  -0.318  -0.339  -0.383  -0.392  -0.401  -0.433
58    N        -0.270  -0.352  -0.333  -0.186  -0.289  -0.238  -0.392  -0.489  -0.455
59    C        -1.216  -1.251  -1.146  -1.012  -1.052  -0.907  -1.004  -1.024  -0.893
60    I        -0.747  -0.795  -0.778  -0.667  -0.756  -0.715  -0.699  -0.749  -0.712
61    P        -0.323  -0.389  -0.369  -0.195  -0.323  -0.326  -0.432  -0.517  -0.490
62    I         0.097   0.147   0.162  -0.120  -0.029  -0.013  -0.215  -0.128  -0.123
63    E        -1.244  -1.192  -1.157  -1.358  -1.278  -1.233  -1.018  -0.966  -0.899
64    V        -0.386  -0.436  -0.377  -0.525  -0.604  -0.529  -0.539  -0.591  -0.509
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    N        -0.782  -0.728  -0.759  -0.755  -0.678  -0.740  -0.759  -0.705  -0.701
68    G        -1.216  -1.243  -1.158  -1.340  -1.386  -1.282  -1.004  -1.017  -0.902
69    N        -1.216  -1.162  -1.135  -1.342  -1.254  -1.219  -1.004  -0.953  -0.885
70    S        -1.532  -1.472  -1.443  -1.350  -1.247  -1.223  -1.126  -1.072  -1.003
71    V        -0.270  -0.246  -0.308  -0.314  -0.282  -0.399  -0.392  -0.357  -0.427
72    I         0.915   0.925   0.910   0.741   0.758   0.698   0.710   0.721   0.624
73    I         0.300   0.334   0.249   0.201   0.245   0.123   0.098   0.143   0.004
74    S         1.939   1.962   2.073   1.692   1.722   1.896   2.179   2.216   2.407
75    K        -0.016  -0.124  -0.222   0.050  -0.102  -0.281  -0.024  -0.168  -0.299
76    Y        -0.016  -0.089  -0.209   0.248   0.146  -0.031  -0.024  -0.124  -0.283
77    N         1.253   1.250   1.127   1.224   1.225   1.040   1.322   1.315   1.063
78    K        -0.016  -0.116  -0.227   0.098  -0.036  -0.209  -0.024  -0.158  -0.306
79    -         0.208   0.286   0.208   0.197   0.310   0.193  -0.015   0.105  -0.044
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    E        -0.347  -0.289  -0.319  -0.601  -0.534  -0.540  -0.514  -0.452  -0.451
82    G        -0.270  -0.260  -0.305  -0.336  -0.308  -0.406  -0.392  -0.371  -0.416
83    A        -1.216  -1.231  -1.145  -1.174  -1.210  -1.070  -1.004  -1.009  -0.893
84    K         0.300   0.252   0.219   0.292   0.216   0.191   0.098   0.008  -0.043
85    F         0.734   0.786   0.850   0.635   0.722   0.801   0.343   0.440   0.495
86    F        -0.466  -0.394  -0.390  -0.494  -0.382  -0.378  -0.636  -0.552  -0.524
87    D         1.939   1.962   2.073   1.884   1.919   2.090   2.179   2.216   2.407
88    P        -1.097  -1.140  -1.128  -0.744  -0.814  -0.829  -0.881  -0.919  -0.873
89    V        -0.016   0.003  -0.188   0.112   0.134  -0.147  -0.024   0.004  -0.254
90    N        -0.270  -0.323  -0.323  -0.401  -0.487  -0.499  -0.392  -0.456  -0.443
91    S        -0.901  -0.924  -0.815  -1.053  -1.067  -0.923  -0.881  -0.893  -0.757
92    V        -0.782  -0.736  -0.767  -0.859  -0.790  -0.852  -0.759  -0.706  -0.708
93    I        -0.782  -0.727  -0.771  -0.880  -0.835  -0.882  -0.759  -0.711  -0.712
94    F         1.939   1.962   2.073   2.024   2.061   2.231   2.179   2.216   2.407
95    S        -0.901  -0.925  -0.828  -1.013  -1.009  -0.878  -0.881  -0.893  -0.767
96    V        -0.270  -0.305  -0.323  -0.275  -0.340  -0.352  -0.392  -0.439  -0.446
97    N         0.915   0.894   0.900   0.791   0.754   0.720   0.710   0.661   0.603
98    H        -0.585  -0.627  -0.704  -0.091  -0.150  -0.263  -0.514  -0.561  -0.632
99    L        -1.216  -1.227  -1.156  -1.110  -1.135  -1.006  -1.004  -1.005  -0.900
100   E        -0.585  -0.452  -0.666  -0.289  -0.097  -0.426  -0.514  -0.353  -0.589
101   R        -0.270  -0.324  -0.313  -0.040  -0.096  -0.085  -0.392  -0.449  -0.430
102   K         0.300   0.282   0.230   0.207   0.152   0.089   0.098   0.049  -0.028
103   G         0.300   0.385   0.286   0.363   0.504   0.337   0.098   0.240   0.072
104   L        -0.901  -0.925  -0.828  -1.107  -1.147  -0.999  -0.881  -0.893  -0.767
105   D         0.599   0.509   0.380   0.725   0.605   0.433   0.588   0.447   0.229
106   I        -0.270  -0.221  -0.288  -0.341  -0.267  -0.380  -0.392  -0.324  -0.398
107   E         0.599   0.593   0.393   0.678   0.669   0.411   0.588   0.579   0.251
108   P        -0.466  -0.429  -0.395  -0.732  -0.692  -0.606  -0.636  -0.598  -0.532
109   Y         0.915   0.919   0.926   0.973   0.978   0.983   0.710   0.709   0.657
110   E        -1.216  -1.182  -1.136  -1.089  -1.016  -0.971  -1.004  -0.967  -0.885
111   F        -1.532  -1.509  -1.444  -1.413  -1.407  -1.273  -1.126  -1.103  -1.004
112   T        -0.782  -0.783  -0.755  -0.763  -0.759  -0.711  -0.759  -0.753  -0.695
113   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   A        -0.992  -0.976  -0.868  -1.060  -1.037  -0.886  -0.955  -0.935  -0.802
115   K         0.359   0.354   0.284   0.328   0.317   0.191   0.220   0.211   0.077
116   I        -0.747  -0.739  -0.767  -0.619  -0.602  -0.626  -0.699  -0.686  -0.700
117   E        -0.883  -0.808  -0.802  -0.715  -0.598  -0.607  -0.859  -0.786  -0.743
118   K        -0.883  -0.833  -0.809  -0.864  -0.789  -0.770  -0.859  -0.804  -0.749
119   G        -1.324  -1.307  -1.201  -1.279  -1.256  -1.107  -1.085  -1.065  -0.936
120   Q        -0.323  -0.360  -0.369  -0.148  -0.216  -0.240  -0.432  -0.481  -0.490
121   L        -0.482  -0.461  -0.412  -0.705  -0.676  -0.623  -0.650  -0.623  -0.548
122   K        -0.466  -0.437  -0.394  -0.774  -0.727  -0.675  -0.636  -0.594  -0.529
123   E        -1.097  -1.094  -1.110  -0.866  -0.871  -0.887  -0.881  -0.877  -0.857
124   L        -0.347  -0.307  -0.325  -0.473  -0.418  -0.421  -0.514  -0.468  -0.457
125   H        -0.782  -0.703  -0.752  -0.637  -0.545  -0.570  -0.759  -0.676  -0.694
126   D        -0.901  -0.928  -0.834  -0.938  -0.955  -0.829  -0.881  -0.896  -0.773
127   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   L         1.253   1.157   1.115   1.281   1.158   1.094   1.322   1.155   1.040
129   H        -1.097  -1.063  -1.085  -1.024  -0.998  -0.990  -0.881  -0.847  -0.834
130   E        -0.782  -0.717  -0.748  -0.786  -0.680  -0.725  -0.759  -0.682  -0.688
131   Y         1.253   1.157   1.115   1.381   1.256   1.201   1.322   1.155   1.040
132   L        -0.901  -0.925  -0.828  -0.861  -0.879  -0.735  -0.881  -0.893  -0.767
133   L        -0.585  -0.521  -0.671  -0.660  -0.567  -0.810  -0.514  -0.434  -0.595
134   Q        -1.097  -1.037  -1.102  -0.880  -0.799  -0.892  -0.881  -0.817  -0.849
135   S        -0.585  -0.485  -0.672  -0.204  -0.046  -0.369  -0.514  -0.393  -0.596
136   F         0.734   0.731   0.826   0.651   0.638   0.767   0.343   0.324   0.444
137   P         1.253   1.157   1.115   1.482   1.362   1.302   1.322   1.155   1.040
138   G         0.199   0.261   0.216  -0.052   0.049  -0.026  -0.059   0.050  -0.039
139   D        -1.216  -1.176  -1.137  -1.136  -1.083  -1.016  -1.004  -0.965  -0.886
140   V        -0.782  -0.763  -0.762  -0.608  -0.593  -0.575  -0.759  -0.740  -0.704
141   S        -0.270  -0.247  -0.317  -0.170  -0.139  -0.269  -0.392  -0.370  -0.438
142   F         0.599   0.593   0.393   0.871   0.872   0.601   0.588   0.579   0.251
143   A        -0.466  -0.420  -0.386  -0.445  -0.367  -0.328  -0.636  -0.571  -0.518
144   V         0.300   0.255   0.228   0.232   0.151   0.108   0.098   0.023  -0.029
145   Y        -0.901  -0.851  -0.811  -0.866  -0.806  -0.740  -0.881  -0.835  -0.754
146   P         0.915   0.862   0.887   0.977   0.878   0.869   0.710   0.596   0.574
147   V        -0.487  -0.437  -0.405  -0.687  -0.612  -0.584  -0.641  -0.582  -0.536
148   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   E        -0.162  -0.216  -0.270  -0.072  -0.155  -0.221  -0.219  -0.292  -0.363
150   E        -0.270  -0.257  -0.309  -0.392  -0.371  -0.482  -0.392  -0.368  -0.427
151   I        -1.532  -1.505  -1.453  -1.479  -1.449  -1.387  -1.126  -1.100  -1.010
152   S        -0.782  -0.845  -0.780  -0.906  -0.990  -0.880  -0.759  -0.816  -0.721
153   K        -0.466  -0.458  -0.406  -0.670  -0.682  -0.589  -0.636  -0.631  -0.546
154   I        -1.216  -1.231  -1.156  -1.101  -1.109  -0.996  -1.004  -1.010  -0.901
155   S        -0.585  -0.586  -0.690  -0.273  -0.268  -0.438  -0.514  -0.516  -0.616
156   I         0.300   0.307   0.241   0.179   0.188   0.075   0.098   0.107  -0.009
157   I         0.734   0.718   0.820   0.416   0.376   0.520   0.343   0.297   0.431
158   I         0.300   0.251   0.226   0.181   0.097   0.053   0.098   0.011  -0.032
159   V         0.915   0.956   0.953   0.773   0.833   0.801   0.710   0.782   0.714
160   S        -0.270  -0.260  -0.305  -0.415  -0.394  -0.446  -0.392  -0.371  -0.416
161   T        -0.901  -0.925  -0.828  -0.872  -0.927  -0.790  -0.881  -0.893  -0.767
162   K         1.253   1.282   1.129   1.268   1.309   1.133   1.322   1.369   1.066
163   Y        -0.016   0.022  -0.200   0.227   0.280  -0.051  -0.024   0.028  -0.271
164   N         0.915   0.913   0.907   0.705   0.697   0.625   0.710   0.698   0.617
165   P        -0.016   0.022  -0.200   0.375   0.429   0.121  -0.024   0.028  -0.271
166   N        -1.532  -1.527  -1.445  -1.504  -1.486  -1.395  -1.126  -1.117  -1.004
167   N         1.253   1.260   1.127   1.251   1.267   1.092   1.322   1.333   1.063
168   F         0.915   0.867   0.899   0.968   0.888   0.910   0.710   0.606   0.601
169   W         0.915   0.956   0.953   1.102   1.167   1.139   0.710   0.782   0.714
170   N         0.734   0.759   0.835   0.516   0.556   0.659   0.343   0.382   0.464
171   G         1.939   1.962   2.073   1.940   1.976   2.147   2.179   2.216   2.407
172   H        -1.532  -1.556  -1.468  -1.171  -1.247  -1.118  -1.126  -1.138  -1.021
173   W         1.939   1.962   2.073   2.165   2.198   2.374   2.179   2.216   2.407
174   R         0.165   0.189   0.197   0.102   0.156   0.162  -0.147  -0.102  -0.088
175   S         1.253   1.157   1.115   1.145   1.038   1.014   1.322   1.155   1.040
176   S        -1.532  -1.535  -1.454  -1.488  -1.503  -1.389  -1.126  -1.122  -1.011
177   Y         1.253   1.157   1.115   1.429   1.321   1.293   1.322   1.155   1.040
178   I        -0.782  -0.799  -0.767  -0.864  -0.889  -0.852  -0.759  -0.770  -0.707
179   Y         0.300   0.333   0.262   0.336   0.393   0.283   0.098   0.152   0.033
180   D        -0.585  -0.627  -0.704  -0.443  -0.509  -0.647  -0.514  -0.561  -0.632
181   L        -0.487  -0.407  -0.394  -0.574  -0.448  -0.445  -0.641  -0.541  -0.522
182   E        -0.487  -0.391  -0.406  -0.719  -0.577  -0.609  -0.641  -0.520  -0.536
183   T        -0.782  -0.753  -0.751  -0.891  -0.851  -0.842  -0.759  -0.723  -0.692
184   R        -1.097  -1.132  -1.099  -0.851  -0.919  -0.869  -0.881  -0.912  -0.847
185   E        -0.782  -0.753  -0.763  -0.932  -0.895  -0.889  -0.759  -0.730  -0.705
186   L         0.677   0.693   0.807   0.318   0.343   0.506   0.220   0.242   0.402
187   S         0.165   0.172   0.183  -0.217  -0.215  -0.179  -0.147  -0.144  -0.112
188   G         1.939   1.962   2.073   1.940   1.976   2.147   2.179   2.216   2.407
189   Q        -1.216  -1.228  -1.143  -1.100  -1.118  -0.999  -1.004  -1.007  -0.891
190   I        -0.016  -0.081  -0.203   0.038  -0.068  -0.256  -0.024  -0.113  -0.275
191   S        -0.466  -0.506  -0.396  -0.662  -0.689  -0.549  -0.636  -0.669  -0.534
192   T        -0.466  -0.426  -0.392  -0.610  -0.565  -0.496  -0.636  -0.593  -0.528
193   Q         0.599   0.561   0.385   0.748   0.701   0.482   0.588   0.522   0.238
194   V        -0.016   0.022  -0.200   0.146   0.196  -0.114  -0.024   0.028  -0.271
195   H         1.939   1.962   2.073   2.130   2.164   2.338   2.179   2.216   2.407
196   Y         1.939   1.962   2.073   1.979   2.010   2.186   2.179   2.216   2.407
197   Y         0.915   0.931   0.912   0.939   0.963   0.913   0.710   0.733   0.628
198   E         1.939   1.962   2.073   1.833   1.859   2.038   2.179   2.216   2.407
199   D         1.939   1.962   2.073   1.884   1.919   2.090   2.179   2.216   2.407
200   G         1.939   1.962   2.073   1.940   1.976   2.147   2.179   2.216   2.407
201   N         1.939   1.962   2.073   1.847   1.882   2.053   2.179   2.216   2.407
202   V         1.939   1.962   2.073   1.874   1.901   2.080   2.179   2.216   2.407
203   S        -0.016   0.005  -0.199   0.295   0.335   0.014  -0.024  -0.003  -0.269
204   F         0.734   0.783   0.850   0.555   0.636   0.723   0.343   0.433   0.497
205   Q        -1.097  -1.075  -1.088  -0.903  -0.888  -0.887  -0.881  -0.858  -0.837
206   S        -0.270  -0.338  -0.321  -0.342  -0.420  -0.377  -0.392  -0.465  -0.437
207   G        -0.782  -0.731  -0.755  -0.928  -0.860  -0.875  -0.759  -0.705  -0.696
208   K        -0.347  -0.403  -0.349  -0.442  -0.501  -0.401  -0.514  -0.565  -0.481
209   D        -1.216  -1.231  -1.145  -1.213  -1.211  -1.096  -1.004  -1.009  -0.893
210   I        -0.347  -0.324  -0.324  -0.464  -0.437  -0.409  -0.514  -0.485  -0.455
211   -        -0.487  -0.461  -0.400  -0.768  -0.723  -0.641  -0.641  -0.606  -0.530
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -         0.713   0.710   0.816   0.420   0.401   0.555   0.299   0.279   0.422
223   N        -0.782  -0.733  -0.753  -0.891  -0.821  -0.847  -0.759  -0.705  -0.695
224   Q         0.300   0.334   0.236   0.064   0.090  -0.032   0.098   0.132  -0.017
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   S        -1.244  -1.254  -1.161  -1.272  -1.291  -1.142  -1.018  -1.022  -0.903
230   N        -0.162  -0.241  -0.298  -0.114  -0.227  -0.337  -0.219  -0.322  -0.400
231   V        -1.216  -1.166  -1.147  -1.037  -0.952  -0.952  -1.004  -0.956  -0.893
232   D         0.300   0.393   0.250   0.049   0.179  -0.036   0.098   0.232   0.008
233   D        -1.097  -1.145  -1.121  -0.988  -1.075  -1.062  -0.881  -0.924  -0.868
234   V        -0.270  -0.279  -0.316  -0.260  -0.270  -0.321  -0.392  -0.397  -0.434
235   V        -0.016  -0.124  -0.222   0.139  -0.013  -0.158  -0.024  -0.168  -0.299
236   C        -1.532  -1.528  -1.464  -1.317  -1.344  -1.212  -1.126  -1.118  -1.018
237   T        -1.216  -1.232  -1.162  -1.149  -1.178  -1.069  -1.004  -1.010  -0.906
238   I         1.253   1.157   1.115   1.224   1.106   1.046   1.322   1.155   1.040
239   R        -0.901  -0.907  -0.829  -1.050  -1.055  -0.918  -0.881  -0.880  -0.769
240   D        -1.216  -1.179  -1.138  -1.158  -1.087  -1.050  -1.004  -0.965  -0.887
241   I        -1.532  -1.524  -1.446  -1.269  -1.260  -1.159  -1.126  -1.115  -1.005
242   E         1.939   1.962   2.073   1.833   1.859   2.038   2.179   2.216   2.407
243   T        -0.585  -0.502  -0.672  -0.364  -0.256  -0.471  -0.514  -0.413  -0.596
244   N        -1.216  -1.222  -1.141  -1.155  -1.156  -1.036  -1.004  -1.002  -0.889
245   F        -0.585  -0.641  -0.708  -0.199  -0.287  -0.371  -0.514  -0.578  -0.636
246   E        -0.347  -0.306  -0.342  -0.280  -0.217  -0.213  -0.514  -0.464  -0.474
247   N        -1.216  -1.177  -1.145  -1.157  -1.099  -1.061  -1.004  -0.966  -0.892
248   D        -0.782  -0.825  -0.781  -0.900  -0.975  -0.930  -0.759  -0.790  -0.718
249   L         0.300   0.240   0.244   0.248   0.184   0.168   0.098   0.022   0.004
250   D        -0.782  -0.679  -0.757  -0.813  -0.669  -0.774  -0.759  -0.652  -0.699
251   L        -0.782  -0.812  -0.780  -0.863  -0.920  -0.870  -0.759  -0.788  -0.720
252   S        -0.585  -0.634  -0.708  -0.626  -0.708  -0.817  -0.514  -0.569  -0.636
253   F         1.253   1.157   1.115   1.428   1.311   1.249   1.322   1.155   1.040
254   F        -0.782  -0.800  -0.773  -0.712  -0.755  -0.691  -0.759  -0.772  -0.714
255   D        -1.216  -1.189  -1.156  -1.297  -1.270  -1.213  -1.004  -0.972  -0.901
256   L         1.253   1.260   1.127   1.335   1.351   1.214   1.322   1.333   1.063
257   N         1.253   1.250   1.127   1.224   1.225   1.040   1.322   1.315   1.063
258   E         0.300   0.240   0.244   0.245   0.162   0.165   0.098   0.022   0.004
259   K        -0.016  -0.033  -0.203   0.112   0.095  -0.150  -0.024  -0.044  -0.275
260   Q        -0.782  -0.826  -0.785  -0.727  -0.804  -0.752  -0.759  -0.798  -0.726
261   F         1.939   1.962   2.073   2.024   2.061   2.231   2.179   2.216   2.407
262   K         1.939   1.962   2.073   1.840   1.873   2.045   2.179   2.216   2.407
263   A        -0.901  -0.901  -0.821  -0.960  -0.957  -0.853  -0.881  -0.876  -0.761
264   L         1.939   1.962   2.073   1.887   1.920   2.093   2.179   2.216   2.407
265   R         1.939   1.962   2.073   2.053   2.082   2.260   2.179   2.216   2.407
266   R         1.939   1.962   2.073   2.053   2.082   2.260   2.179   2.216   2.407
267   R        -0.032  -0.004   0.092  -0.088  -0.046   0.088  -0.392  -0.352  -0.230
268   L         1.939   1.962   2.073   1.887   1.920   2.093   2.179   2.216   2.407
269   P         1.939   1.962   2.073   2.079   2.113   2.286   2.179   2.216   2.407
270   V         1.253   1.341   1.138   1.269   1.376   1.118   1.322   1.464   1.083
271   T         1.939   1.962   2.073   2.015   2.049   2.222   2.179   2.216   2.407
272   R         1.939   1.962   2.073   2.053   2.082   2.260   2.179   2.216   2.407
273   S         0.046   0.033   0.110  -0.204  -0.220  -0.101  -0.269  -0.293  -0.199
274   K         1.253   1.341   1.138   1.268   1.375   1.146   1.322   1.464   1.083
275   I         1.253   1.341   1.138   1.222   1.336   1.078   1.322   1.464   1.083
276   N         1.253   1.250   1.127   1.244   1.245   1.077   1.322   1.315   1.063
277   W         1.939   1.962   2.073   2.165   2.198   2.374   2.179   2.216   2.407
278   G         0.599   0.490   0.374   0.746   0.597   0.416   0.588   0.420   0.221
279   S        -0.466  -0.499  -0.399  -0.680  -0.717  -0.586  -0.636  -0.661  -0.537
280   A         0.359   0.273   0.237   0.449   0.300   0.211   0.220   0.084   0.002
281   I         0.915   0.857   0.898   0.737   0.635   0.671   0.710   0.586   0.600
282   G         0.300   0.243   0.218   0.247   0.138   0.084   0.098   0.001  -0.044
283   S         0.300   0.235   0.233   0.145   0.067   0.010   0.098   0.015  -0.020
284   Y         1.253   1.157   1.115   1.374   1.248   1.186   1.322   1.155   1.040
285   R         1.939   1.962   2.073   2.053   2.082   2.260   2.179   2.216   2.407
286   L         1.253   1.157   1.115   1.335   1.229   1.198   1.322   1.155   1.040
287   G         1.253   1.157   1.115   1.368   1.256   1.212   1.322   1.155   1.040
288   K        -0.901  -0.935  -0.826  -0.979  -1.024  -0.852  -0.881  -0.902  -0.766
289   N         1.192   1.253   1.083   1.200   1.286   1.043   1.219   1.321   0.977
290   A        -0.026  -0.026   0.079  -0.220  -0.232  -0.088  -0.379  -0.381  -0.246
291   A        -0.747  -0.779  -0.786  -0.607  -0.661  -0.717  -0.699  -0.730  -0.720
292   E        -1.244  -1.245  -1.169  -1.019  -1.026  -0.926  -1.018  -1.014  -0.909
293   G         0.489   0.527   0.317   0.576   0.630   0.298   0.420   0.479   0.130
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   K        -0.585  -0.678  -0.720  -0.396  -0.520  -0.578  -0.514  -0.619  -0.649
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P28495
Output conservation file - output/P28495
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
