1     M         1.059   1.059   1.085   1.190   1.190   1.216   1.120   1.120   1.158
2     S         0.333   0.309  -0.012   0.349   0.322  -0.090   0.357   0.323  -0.204
3     S         0.333   0.381  -0.009   0.340   0.395  -0.109   0.357   0.423  -0.198
4     S        -0.676  -0.628  -0.790  -0.611  -0.539  -0.824  -0.733  -0.667  -0.872
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -0.216  -0.227  -0.120  -0.244  -0.263  -0.114  -0.515  -0.533  -0.392
7     R         1.059   1.059   1.085   1.235   1.232   1.255   1.120   1.120   1.158
8     R         1.059   1.059   1.085   1.235   1.232   1.255   1.120   1.120   1.158
9     I         1.059   1.059   1.085   1.059   1.061   1.100   1.120   1.120   1.158
10    E         1.059   1.059   1.085   0.935   0.936   0.990   1.120   1.120   1.158
11    T        -0.025  -0.048  -0.081   0.111   0.071  -0.038  -0.188  -0.226  -0.324
12    D         1.059   1.059   1.085   0.748   0.752   0.825   1.120   1.120   1.158
13    V         1.059   1.059   1.085   1.070   1.069   1.109   1.120   1.120   1.158
14    M         1.059   1.059   1.085   1.190   1.190   1.216   1.120   1.120   1.158
15    K        -0.359  -0.397  -0.753  -0.183  -0.234  -0.875  -0.297  -0.345  -0.824
16    L         1.059   1.059   1.085   0.983   0.984   1.032   1.120   1.120   1.158
17    L        -0.094  -0.116  -0.094  -0.167  -0.200  -0.174  -0.304  -0.340  -0.346
18    M         1.059   1.059   1.085   1.195   1.194   1.220   1.120   1.120   1.158
19    S         1.059   1.059   1.085   0.922   0.919   0.979   1.120   1.120   1.158
20    D         1.059   1.059   1.085   0.727   0.732   0.806   1.120   1.120   1.158
21    H        -0.094  -0.132  -0.104   0.097   0.034   0.016  -0.304  -0.368  -0.364
22    Q        -0.877  -0.864  -0.809  -1.200  -1.182  -1.005  -1.016  -1.003  -0.901
23    V         1.059   1.059   1.085   1.078   1.076   1.117   1.120   1.120   1.158
24    D        -1.403  -1.371  -1.319  -1.299  -1.227  -1.237  -1.301  -1.261  -1.174
25    L         1.059   1.059   1.085   0.983   0.984   1.032   1.120   1.120   1.158
26    I        -0.257  -0.261  -0.134  -0.429  -0.439  -0.251  -0.589  -0.594  -0.417
27    N        -1.021  -1.003  -0.827  -1.330  -1.298  -1.047  -1.158  -1.136  -0.918
28    D         1.059   1.059   1.085   0.727   0.732   0.806   1.120   1.120   1.158
29    S        -0.476  -0.498  -0.751  -0.416  -0.450  -0.808  -0.446  -0.477  -0.822
30    M        -0.025  -0.048  -0.081   0.092   0.054  -0.059  -0.188  -0.226  -0.324
31    Q         1.059   1.059   1.085   1.275   1.273   1.291   1.120   1.120   1.158
32    E        -0.359  -0.397  -0.753  -0.238  -0.283  -0.760  -0.297  -0.345  -0.824
33    F         1.059   1.059   1.085   1.201   1.198   1.225   1.120   1.120   1.158
34    H        -0.819  -0.841  -0.807  -0.579  -0.612  -0.564  -0.951  -0.976  -0.896
35    V         0.333   0.357  -0.009   0.466   0.493  -0.026   0.357   0.390  -0.198
36    K        -1.027  -1.033  -0.842  -0.997  -1.006  -0.758  -1.169  -1.176  -0.938
37    F         1.059   1.059   1.085   1.201   1.198   1.225   1.120   1.120   1.158
38    L        -1.613  -1.590  -1.673  -1.088  -1.057  -1.302  -1.278  -1.258  -1.305
39    G         1.059   1.059   1.085   1.139   1.139   1.171   1.120   1.120   1.158
40    P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
41    K        -1.821  -1.854  -1.720  -1.662  -1.708  -1.558  -1.497  -1.525  -1.346
42    D        -0.216  -0.227  -0.120  -0.710  -0.726  -0.533  -0.515  -0.533  -0.392
43    T         1.059   1.059   1.085   1.201   1.199   1.225   1.120   1.120   1.158
44    P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
45    Y        -0.025  -0.045  -0.077   0.124   0.091   0.004  -0.188  -0.221  -0.315
46    E        -1.010  -0.992  -1.263  -0.798  -0.780  -1.130  -0.842  -0.822  -1.117
47    N        -0.359  -0.323  -0.732  -0.051  -0.008  -0.610  -0.297  -0.251  -0.796
48    G         1.059   1.059   1.085   1.139   1.139   1.171   1.120   1.120   1.158
49    V        -0.819  -0.836  -0.806  -0.816  -0.842  -0.758  -0.951  -0.971  -0.896
50    W         1.059   1.059   1.085   1.312   1.312   1.323   1.120   1.120   1.158
51    R        -0.216  -0.191  -0.115  -0.244  -0.207  -0.107  -0.515  -0.471  -0.384
52    L        -1.027  -1.041  -0.842  -1.176  -1.194  -0.905  -1.169  -1.185  -0.937
53    H        -0.216  -0.244  -0.128  -0.081  -0.133   0.004  -0.515  -0.564  -0.407
54    V         1.059   1.059   1.085   1.070   1.069   1.109   1.120   1.120   1.158
55    E         1.059   1.059   1.085   0.935   0.936   0.990   1.120   1.120   1.158
56    L         1.059   1.059   1.085   0.992   0.995   1.041   1.120   1.120   1.158
57    P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
58    D        -0.359  -0.323  -0.733  -0.471  -0.425  -0.979  -0.297  -0.252  -0.798
59    N        -1.027  -1.014  -0.841  -1.021  -0.990  -0.786  -1.169  -1.154  -0.936
60    Y         1.059   1.059   1.085   1.177   1.177   1.204   1.120   1.120   1.158
61    P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
62    Y        -0.676  -0.700  -0.785  -0.440  -0.479  -0.601  -0.733  -0.766  -0.866
63    K         1.059   1.059   1.085   1.087   1.088   1.125   1.120   1.120   1.158
64    S         1.059   1.059   1.085   0.932   0.933   0.987   1.120   1.120   1.158
65    P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
66    S         1.059   1.059   1.085   0.932   0.933   0.987   1.120   1.120   1.158
67    I         1.059   1.059   1.085   1.059   1.061   1.100   1.120   1.120   1.158
68    G         1.059   1.059   1.085   1.139   1.139   1.171   1.120   1.120   1.158
69    F         1.059   1.059   1.085   1.201   1.198   1.225   1.120   1.120   1.158
70    V        -0.359  -0.397  -0.753  -0.106  -0.154  -0.664  -0.297  -0.345  -0.824
71    N         1.059   1.059   1.085   1.091   1.091   1.128   1.120   1.120   1.158
72    K        -0.025  -0.070  -0.081   0.049  -0.019  -0.056  -0.188  -0.264  -0.323
73    I         1.059   1.059   1.085   1.059   1.061   1.100   1.120   1.120   1.158
74    F        -0.025  -0.048  -0.081   0.139   0.100   0.003  -0.188  -0.226  -0.324
75    H         1.059   1.059   1.085   1.278   1.279   1.294   1.120   1.120   1.158
76    P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
77    N         1.059   1.059   1.085   1.091   1.091   1.128   1.120   1.120   1.158
78    I         1.059   1.059   1.085   1.059   1.061   1.100   1.120   1.120   1.158
79    D         1.059   1.059   1.085   0.748   0.752   0.825   1.120   1.120   1.158
80    I        -0.676  -0.625  -0.793  -0.688  -0.617  -0.826  -0.733  -0.665  -0.878
81    A        -1.361  -1.382  -1.331  -1.176  -1.209  -1.108  -1.278  -1.294  -1.186
82    S         1.059   1.059   1.085   0.932   0.933   0.987   1.120   1.120   1.158
83    G         1.059   1.059   1.085   1.139   1.139   1.171   1.120   1.120   1.158
84    S         1.059   1.059   1.085   0.932   0.933   0.987   1.120   1.120   1.158
85    I        -0.216  -0.191  -0.115  -0.353  -0.309  -0.215  -0.515  -0.471  -0.384
86    C         1.059   1.059   1.085   1.351   1.351   1.358   1.120   1.120   1.158
87    L         1.059   1.059   1.085   0.992   0.995   1.041   1.120   1.120   1.158
88    D         1.059   1.059   1.085   0.748   0.752   0.825   1.120   1.120   1.158
89    V         1.059   1.059   1.085   1.070   1.069   1.109   1.120   1.120   1.158
90    I         1.059   1.059   1.085   1.059   1.061   1.100   1.120   1.120   1.158
91    N         1.059   1.059   1.085   1.091   1.091   1.128   1.120   1.120   1.158
92    S        -0.216  -0.191  -0.115  -0.236  -0.184  -0.131  -0.515  -0.471  -0.384
93    T         1.059   1.059   1.085   1.201   1.199   1.225   1.120   1.120   1.158
94    W         1.059   1.059   1.085   1.312   1.312   1.323   1.120   1.120   1.158
95    S         1.059   1.059   1.085   0.932   0.933   0.987   1.120   1.120   1.158
96    P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
97    L        -0.216  -0.191  -0.115  -0.280  -0.231  -0.162  -0.515  -0.471  -0.384
98    Y        -0.216  -0.191  -0.115  -0.177  -0.137  -0.057  -0.515  -0.471  -0.384
99    D        -0.025  -0.048  -0.081  -0.310  -0.341  -0.364  -0.188  -0.226  -0.324
100   L        -0.216  -0.227  -0.120  -0.350  -0.366  -0.206  -0.515  -0.533  -0.392
101   I        -0.819  -0.796  -0.804  -0.907  -0.886  -0.857  -0.951  -0.935  -0.895
102   N         1.059   1.059   1.085   1.091   1.091   1.128   1.120   1.120   1.158
103   I         1.059   1.059   1.085   1.059   1.061   1.100   1.120   1.120   1.158
104   V        -0.216  -0.191  -0.115  -0.232  -0.189  -0.114  -0.515  -0.471  -0.384
105   E         1.059   1.059   1.085   0.935   0.936   0.990   1.120   1.120   1.158
106   W        -1.027  -1.033  -0.842  -0.943  -0.963  -0.715  -1.169  -1.176  -0.938
107   M        -0.216  -0.191  -0.115  -0.170  -0.131  -0.050  -0.515  -0.471  -0.384
108   I        -0.025  -0.002  -0.070  -0.099  -0.063  -0.194  -0.188  -0.151  -0.305
109   P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
110   G        -1.027  -1.033  -0.842  -0.843  -0.848  -0.607  -1.169  -1.176  -0.938
111   L         1.059   1.059   1.085   0.992   0.995   1.041   1.120   1.120   1.158
112   L         1.059   1.059   1.085   0.992   0.995   1.041   1.120   1.120   1.158
113   K        -0.216  -0.191  -0.115  -0.193  -0.149  -0.080  -0.515  -0.471  -0.384
114   E        -0.216  -0.191  -0.115  -0.322  -0.270  -0.202  -0.515  -0.471  -0.384
115   P        -0.025  -0.048  -0.081   0.013  -0.026  -0.092  -0.188  -0.226  -0.324
116   N         1.059   1.059   1.085   1.091   1.091   1.128   1.120   1.120   1.158
117   G        -0.819  -0.808  -0.810  -0.775  -0.759  -0.725  -0.951  -0.931  -0.900
118   S         0.333   0.257  -0.013   0.349   0.261  -0.092   0.357   0.248  -0.206
119   D         1.059   1.059   1.085   0.748   0.752   0.825   1.120   1.120   1.158
120   P         1.059   1.059   1.085   1.059   1.058   1.100   1.120   1.120   1.158
121   L         1.059   1.059   1.085   0.992   0.995   1.041   1.120   1.120   1.158
122   N         1.059   1.059   1.085   1.091   1.091   1.128   1.120   1.120   1.158
123   N        -1.027  -1.033  -0.842  -0.996  -1.005  -0.744  -1.169  -1.176  -0.938
124   E         1.059   1.059   1.085   0.935   0.936   0.990   1.120   1.120   1.158
125   A         1.059   1.059   1.085   1.204   1.199   1.228   1.120   1.120   1.158
126   A        -0.216  -0.216  -0.126  -0.299  -0.303  -0.214  -0.515  -0.514  -0.404
127   T        -1.487  -1.473  -1.326  -1.233  -1.226  -1.044  -1.387  -1.379  -1.182
128   L        -0.025  -0.045  -0.077  -0.056  -0.085  -0.143  -0.188  -0.221  -0.315
129   Q        -1.027  -1.033  -0.842  -0.973  -0.991  -0.731  -1.169  -1.176  -0.938
130   L        -0.676  -0.658  -0.788  -0.582  -0.568  -0.716  -0.733  -0.721  -0.870
131   R        -0.277  -0.276  -0.134  -0.330  -0.330  -0.127  -0.624  -0.623  -0.418
132   D        -0.216  -0.227  -0.120  -0.710  -0.726  -0.533  -0.515  -0.533  -0.392
133   K        -1.027  -1.033  -0.842  -1.171  -1.186  -0.921  -1.169  -1.176  -0.938
134   K        -1.010  -1.015  -1.259  -0.720  -0.724  -1.148  -0.842  -0.848  -1.112
135   L        -2.281  -2.230  -2.059  -1.812  -1.755  -1.553  -1.715  -1.680  -1.465
136   Y         1.059   1.059   1.085   1.177   1.177   1.204   1.120   1.120   1.158
137   E        -0.676  -0.700  -0.785  -0.681  -0.717  -0.809  -0.733  -0.766  -0.866
138   E        -1.821  -1.859  -1.715  -1.787  -1.851  -1.560  -1.497  -1.529  -1.340
139   K        -0.025  -0.048  -0.081   0.038   0.004  -0.072  -0.188  -0.226  -0.324
140   I        -0.025  -0.002  -0.070  -0.024   0.009  -0.133  -0.188  -0.151  -0.305
141   K        -0.676  -0.636  -0.781  -0.465  -0.414  -0.595  -0.733  -0.681  -0.864
142   E        -0.676  -0.678  -0.775  -0.832  -0.822  -0.996  -0.733  -0.729  -0.854
143   Y         1.059   1.059   1.085   1.177   1.177   1.204   1.120   1.120   1.158
144   I        -0.277  -0.275  -0.134  -0.470  -0.468  -0.252  -0.624  -0.620  -0.418
145   D        -1.947  -1.936  -1.727  -1.719  -1.686  -1.410  -1.606  -1.596  -1.351
146   K        -0.676  -0.707  -0.795  -0.465  -0.505  -0.614  -0.733  -0.771  -0.882
147   Y         1.059   1.059   1.085   1.177   1.177   1.204   1.120   1.120   1.158
148   A         1.059   1.059   1.085   1.204   1.199   1.228   1.120   1.120   1.158
149   T        -1.487  -1.504  -1.344  -1.380  -1.418  -1.214  -1.387  -1.405  -1.198
150   K        -0.216  -0.216  -0.126  -0.321  -0.320  -0.206  -0.515  -0.514  -0.404
151   E        -0.783  -0.892  -0.808  -1.025  -1.183  -1.065  -0.874  -1.001  -0.896
152   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   D        -1.821  -1.847  -1.696  -1.858  -1.886  -1.654  -1.497  -1.518  -1.327
163   S        -2.281  -2.259  -2.058  -1.983  -1.942  -1.709  -1.715  -1.699  -1.464
164   D        -0.359  -0.333  -0.732  -0.499  -0.464  -1.043  -0.297  -0.266  -0.796
165   D        -1.279  -1.311  -1.305  -1.418  -1.471  -1.391  -1.169  -1.205  -1.162
166   S        -1.361  -1.393  -1.288  -1.266  -1.297  -1.155  -1.278  -1.305  -1.148
167   D        -0.476  -0.519  -0.748  -0.621  -0.668  -0.973  -0.446  -0.501  -0.818
168   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   E        -1.928  -1.954  -1.728  -1.931  -1.971  -1.614  -1.585  -1.604  -1.351
176   D        -1.010  -1.106  -1.284  -1.025  -1.153  -1.365  -0.842  -0.950  -1.138
177   S        -1.487  -1.453  -1.327  -1.789  -1.742  -1.527  -1.387  -1.356  -1.182
178   D        -0.676  -0.721  -0.792  -0.978  -1.030  -1.140  -0.733  -0.779  -0.876
179   S        -1.010  -0.937  -1.285  -1.074  -0.977  -1.463  -0.842  -0.760  -1.139
180   D         1.059   1.059   1.085   0.748   0.752   0.825   1.120   1.120   1.158
181   E        -1.279  -1.283  -1.290  -1.378  -1.387  -1.336  -1.169  -1.184  -1.148
182   D        -0.819  -0.836  -0.807  -1.165  -1.185  -1.042  -0.951  -0.975  -0.898
183   M        -0.819  -0.778  -0.807  -0.827  -0.779  -0.786  -0.951  -0.908  -0.898
184   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   T         0.333   0.348  -0.010   0.349   0.367  -0.086   0.357   0.379  -0.200
189   G        -0.819  -0.814  -0.808  -1.182  -1.177  -1.072  -0.951  -0.949  -0.897
190   V        -1.279  -1.212  -1.290  -1.210  -1.109  -1.306  -1.169  -1.098  -1.146
191   S        -1.403  -1.423  -1.327  -1.313  -1.321  -1.229  -1.301  -1.315  -1.182
192   S        -0.476  -0.385  -0.745  -0.431  -0.309  -0.848  -0.446  -0.331  -0.814
193   G        -1.928  -1.873  -1.738  -1.634  -1.567  -1.391  -1.585  -1.543  -1.359
194   D        -0.877  -0.841  -0.810  -1.211  -1.176  -1.017  -1.016  -0.981  -0.901
195   D        -1.361  -1.404  -1.325  -1.612  -1.661  -1.472  -1.278  -1.314  -1.181
196   S        -0.676  -0.701  -0.779  -0.977  -1.023  -1.120  -0.733  -0.775  -0.859
197   V        -1.279  -1.245  -1.311  -1.438  -1.387  -1.449  -1.169  -1.127  -1.166
198   D        -1.010  -0.989  -1.259  -1.014  -0.990  -1.314  -0.842  -0.819  -1.113
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   S        -1.279  -1.281  -1.289  -1.376  -1.370  -1.430  -1.169  -1.166  -1.145
203   E        -1.010  -1.025  -1.276  -0.865  -0.889  -1.276  -0.842  -0.858  -1.131
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   D        -2.281  -2.282  -2.058  -2.220  -2.197  -1.893  -1.715  -1.714  -1.464
207   L        -0.676  -0.617  -0.791  -0.486  -0.407  -0.718  -0.733  -0.660  -0.873
208   S        -0.216  -0.191  -0.115  -0.357  -0.307  -0.232  -0.515  -0.471  -0.384
209   D        -1.821  -1.873  -1.725  -2.002  -2.065  -1.808  -1.497  -1.537  -1.349
210   I        -1.361  -1.341  -1.319  -1.174  -1.141  -1.111  -1.278  -1.260  -1.175
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   D        -0.216  -0.233  -0.127  -0.641  -0.679  -0.519  -0.515  -0.545  -0.404
214   V        -0.676  -0.666  -0.781  -0.587  -0.570  -0.756  -0.733  -0.717  -0.865
215   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P28263
Output conservation file - output/P28263
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
