1     M         1.085   1.109   1.168   1.314   1.341   1.419   1.157   1.186   1.270
2     -        -1.295  -1.144  -1.094  -1.308  -1.077  -1.023  -1.334  -1.143  -1.053
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S        -1.550  -1.615  -1.466  -1.419  -1.540  -1.331  -1.385  -1.429  -1.217
6     I        -0.843  -0.747  -0.625  -1.194  -1.037  -0.843  -1.103  -0.967  -0.792
7     T        -1.392  -1.379  -1.429  -1.185  -1.196  -1.274  -1.222  -1.195  -1.186
8     K        -2.011  -1.906  -1.763  -2.053  -1.907  -1.691  -1.654  -1.544  -1.323
9     T         0.412   0.299   0.156   0.469   0.318   0.088   0.400   0.222  -0.052
10    E        -1.585  -1.557  -1.448  -1.495  -1.460  -1.282  -1.438  -1.382  -1.203
11    L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
12    D        -0.833  -0.952  -1.038  -0.717  -0.876  -1.064  -0.789  -0.923  -0.993
13    G        -0.229  -0.412  -0.540  -0.078  -0.327  -0.552  -0.249  -0.495  -0.676
14    I        -1.550  -1.611  -1.466  -1.434  -1.489  -1.311  -1.385  -1.426  -1.217
15    L         0.080   0.058   0.059  -0.093  -0.122  -0.113  -0.141  -0.187  -0.231
16    P         0.412   0.340   0.153   0.583   0.488   0.189   0.400   0.287  -0.058
17    L         0.080  -0.011   0.047  -0.183  -0.355  -0.280  -0.141  -0.313  -0.253
18    V        -0.523  -0.641  -0.588  -0.596  -0.789  -0.744  -0.681  -0.826  -0.747
19    A        -0.229  -0.293  -0.521  -0.063  -0.163  -0.443  -0.249  -0.337  -0.651
20    R        -0.833  -0.958  -1.039  -0.558  -0.745  -0.949  -0.789  -0.932  -0.995
21    G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
22    K         1.085   1.109   1.168   0.925   0.960   1.072   1.157   1.186   1.270
23    V         1.085   1.109   1.168   1.054   1.082   1.186   1.157   1.186   1.270
24    R         1.085   1.109   1.168   1.191   1.223   1.309   1.157   1.186   1.270
25    D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
26    I        -0.097  -0.117   0.025  -0.436  -0.499  -0.269  -0.465  -0.511  -0.295
27    Y         1.085   1.109   1.168   1.199   1.230   1.316   1.157   1.186   1.270
28    E        -0.656  -0.637  -0.591  -0.799  -0.757  -0.670  -0.898  -0.843  -0.751
29    V        -0.229  -0.412  -0.540  -0.065  -0.304  -0.482  -0.249  -0.495  -0.676
30    D        -0.229  -0.343  -0.541  -0.103  -0.242  -0.535  -0.249  -0.399  -0.679
31    A        -0.523  -0.395  -0.572  -0.616  -0.449  -0.714  -0.681  -0.526  -0.725
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    G        -2.321  -2.208  -2.028  -1.978  -1.858  -1.622  -1.763  -1.653  -1.405
35    T        -0.229  -0.343  -0.541  -0.083  -0.232  -0.535  -0.249  -0.399  -0.679
36    L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
37    L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
38    F         1.085   1.109   1.168   1.195   1.229   1.313   1.157   1.186   1.270
39    V         1.085   1.109   1.168   1.054   1.082   1.186   1.157   1.186   1.270
40    A         0.412   0.299   0.156   0.464   0.311   0.095   0.400   0.222  -0.052
41    T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
42    D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
43    R         1.085   1.109   1.168   1.191   1.223   1.309   1.157   1.186   1.270
44    I         0.412   0.476   0.164   0.426   0.513   0.075   0.400   0.492  -0.038
45    S         1.085   1.109   1.168   1.078   1.110   1.209   1.157   1.186   1.270
46    A         1.085   1.109   1.168   1.047   1.072   1.181   1.157   1.186   1.270
47    Y         1.085   1.109   1.168   1.199   1.230   1.316   1.157   1.186   1.270
48    D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
49    V         0.412   0.340   0.153   0.490   0.403   0.145   0.400   0.287  -0.058
50    I         1.085   1.109   1.168   1.010   1.047   1.147   1.157   1.186   1.270
51    M         1.085   1.109   1.168   1.314   1.341   1.419   1.157   1.186   1.270
52    E        -1.082  -1.055  -1.064  -1.199  -1.177  -1.177  -1.114  -1.085  -1.025
53    N         1.085   1.109   1.168   1.229   1.262   1.343   1.157   1.186   1.270
54    S        -0.833  -0.525  -1.005  -0.643  -0.240  -0.928  -0.789  -0.410  -0.957
55    I         0.412   0.299   0.156   0.426   0.285   0.061   0.400   0.222  -0.052
56    P         0.412   0.476   0.164   0.585   0.663   0.216   0.400   0.492  -0.038
57    E        -1.392  -1.360  -1.422  -1.242  -1.187  -1.267  -1.222  -1.177  -1.179
58    K         1.085   1.109   1.168   0.925   0.960   1.072   1.157   1.186   1.270
59    G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
60    I        -1.082  -0.988  -1.050  -1.216  -1.056  -1.149  -1.114  -0.976  -1.007
61    L        -0.656  -0.623  -0.586  -0.925  -0.809  -0.768  -0.898  -0.808  -0.743
62    L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
63    T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
64    K        -0.833  -0.929  -1.041  -0.741  -0.862  -0.993  -0.789  -0.897  -0.996
65    L        -0.097  -0.094   0.026  -0.471  -0.468  -0.268  -0.465  -0.468  -0.292
66    S         0.412   0.299   0.156   0.495   0.349   0.121   0.400   0.222  -0.052
67    E        -0.229  -0.379  -0.538  -0.232  -0.437  -0.710  -0.249  -0.450  -0.674
68    F         0.412   0.299   0.156   0.644   0.514   0.303   0.400   0.222  -0.052
69    W         1.085   1.109   1.168   1.292   1.322   1.400   1.157   1.186   1.270
70    F         1.085   1.109   1.168   1.195   1.229   1.313   1.157   1.186   1.270
71    K        -1.701  -1.670  -1.464  -1.853  -1.782  -1.470  -1.546  -1.485  -1.218
72    F        -0.523  -0.630  -0.602  -0.444  -0.645  -0.649  -0.681  -0.832  -0.765
73    L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
74    S        -1.585  -1.607  -1.450  -1.606  -1.625  -1.379  -1.438  -1.422  -1.205
75    N        -2.038  -1.948  -1.769  -1.990  -1.874  -1.601  -1.668  -1.567  -1.326
76    D        -1.684  -1.695  -1.469  -1.650  -1.613  -1.302  -1.526  -1.501  -1.220
77    V        -0.153  -0.110   0.027  -0.468  -0.396  -0.173  -0.573  -0.498  -0.291
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    R        -1.585  -1.586  -1.461  -1.462  -1.502  -1.318  -1.438  -1.416  -1.215
82    N         0.080  -0.011   0.047   0.166  -0.009   0.032  -0.141  -0.313  -0.253
83    H         1.085   1.109   1.168   1.294   1.324   1.402   1.157   1.186   1.270
84    L        -0.229  -0.379  -0.538  -0.223  -0.407  -0.631  -0.249  -0.450  -0.674
85    V        -1.082  -0.943  -1.051  -1.146  -0.921  -1.117  -1.114  -0.930  -1.010
86    D        -2.392  -2.298  -2.043  -2.424  -2.296  -1.927  -1.809  -1.710  -1.414
87    I        -1.197  -1.032  -1.072  -1.289  -1.001  -1.117  -1.244  -1.033  -1.031
88    A        -2.392  -2.298  -2.043  -2.127  -1.993  -1.662  -1.809  -1.710  -1.414
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    G        -0.613  -0.708  -0.624  -0.597  -0.743  -0.643  -0.781  -0.911  -0.790
92    K        -0.800  -0.826  -0.634  -1.163  -1.187  -0.878  -1.058  -1.069  -0.804
93    T        -0.613  -0.708  -0.624  -0.519  -0.659  -0.531  -0.781  -0.911  -0.790
94    I        -0.465  -0.367  -0.575  -0.525  -0.379  -0.742  -0.573  -0.432  -0.724
95    F        -0.338  -0.527  -0.579  -0.094  -0.358  -0.502  -0.397  -0.654  -0.731
96    D        -1.275  -1.314  -1.103  -1.449  -1.504  -1.184  -1.330  -1.338  -1.064
97    Y        -2.011  -1.947  -1.767  -2.065  -1.996  -1.675  -1.654  -1.573  -1.325
98    L        -0.229  -0.320  -0.520  -0.221  -0.337  -0.601  -0.249  -0.372  -0.649
99    P         1.085   1.109   1.168   1.166   1.194   1.287   1.157   1.186   1.270
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   A         0.016  -0.056   0.039  -0.080  -0.216  -0.063  -0.255  -0.395  -0.268
102   K        -1.197  -1.199  -1.092  -1.332  -1.327  -1.136  -1.244  -1.234  -1.052
103   L        -0.976  -1.142  -1.078  -0.992  -1.224  -1.124  -0.962  -1.142  -1.036
104   S        -1.392  -1.541  -1.451  -1.169  -1.405  -1.297  -1.222  -1.355  -1.205
105   E        -1.894  -1.949  -1.769  -1.871  -1.976  -1.719  -1.546  -1.567  -1.326
106   P        -1.197  -1.119  -1.078  -1.189  -1.099  -1.051  -1.244  -1.155  -1.039
107   K         0.016  -0.070   0.032  -0.268  -0.438  -0.279  -0.255  -0.423  -0.282
108   Y        -0.338  -0.538  -0.579  -0.142  -0.457  -0.611  -0.397  -0.670  -0.731
109   K        -1.082  -1.124  -1.069  -1.070  -1.100  -0.990  -1.114  -1.129  -1.029
110   T        -2.011  -1.846  -1.762  -1.950  -1.732  -1.588  -1.654  -1.501  -1.322
111   Q        -0.833  -1.031  -1.060  -0.534  -0.830  -0.940  -0.789  -1.013  -1.017
112   L         0.080   0.049   0.057  -0.155  -0.208  -0.215  -0.141  -0.204  -0.235
113   E        -1.082  -1.154  -1.081  -1.189  -1.301  -1.158  -1.114  -1.185  -1.042
114   D        -0.097  -0.078   0.027  -0.312  -0.283  -0.138  -0.465  -0.437  -0.290
115   R         1.085   1.109   1.168   1.191   1.223   1.309   1.157   1.186   1.270
116   S        -0.229  -0.179  -0.519  -0.034   0.035  -0.420  -0.249  -0.182  -0.648
117   L         0.080  -0.011   0.047  -0.052  -0.176  -0.062  -0.141  -0.313  -0.253
118   L         0.412   0.299   0.156   0.351   0.222   0.033   0.400   0.222  -0.052
119   V         1.085   1.109   1.168   1.054   1.082   1.186   1.157   1.186   1.270
120   H        -1.392  -1.294  -1.426  -0.991  -0.890  -1.075  -1.222  -1.113  -1.183
121   K         1.085   1.109   1.168   0.925   0.960   1.072   1.157   1.186   1.270
122   H        -0.848  -0.816  -0.639  -0.935  -0.909  -0.635  -1.114  -1.055  -0.810
123   K         1.085   1.109   1.168   0.925   0.960   1.072   1.157   1.186   1.270
124   L        -0.523  -0.663  -0.602  -0.703  -0.912  -0.814  -0.681  -0.860  -0.765
125   I        -0.833  -1.031  -1.060  -0.717  -0.995  -1.077  -0.789  -1.013  -1.017
126   P         1.085   1.109   1.168   1.166   1.194   1.287   1.157   1.186   1.270
127   L        -0.097  -0.117   0.025  -0.471  -0.507  -0.268  -0.465  -0.511  -0.295
128   E         1.085   1.109   1.168   0.953   0.989   1.096   1.157   1.186   1.270
129   V        -0.097  -0.117   0.025  -0.326  -0.389  -0.151  -0.465  -0.511  -0.295
130   I         1.085   1.109   1.168   1.010   1.047   1.147   1.157   1.186   1.270
131   V         1.085   1.109   1.168   1.054   1.082   1.186   1.157   1.186   1.270
132   R         1.085   1.109   1.168   1.191   1.223   1.309   1.157   1.186   1.270
133   G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
134   Y         0.080   0.223   0.098   0.179   0.391   0.171  -0.141   0.098  -0.158
135   I         1.085   1.109   1.168   1.010   1.047   1.147   1.157   1.186   1.270
136   T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
137   G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
138   S         1.085   1.109   1.168   1.078   1.110   1.209   1.157   1.186   1.270
139   A         0.412   0.446   0.167   0.467   0.506   0.121   0.400   0.448  -0.032
140   W         1.085   1.109   1.168   1.292   1.322   1.400   1.157   1.186   1.270
141   K        -0.229  -0.379  -0.538  -0.202  -0.385  -0.600  -0.249  -0.450  -0.674
142   E         1.085   1.109   1.168   0.953   0.989   1.096   1.157   1.186   1.270
143   Y         1.085   1.109   1.168   1.199   1.230   1.316   1.157   1.186   1.270
144   V        -1.082  -1.018  -1.063  -1.126  -1.045  -1.066  -1.114  -1.060  -1.024
145   K        -0.229  -0.088  -0.506  -0.207  -0.026  -0.565  -0.249  -0.056  -0.630
146   T        -1.275  -1.271  -1.096  -1.392  -1.358  -1.105  -1.330  -1.295  -1.057
147   G         0.080   0.135   0.084  -0.020   0.070  -0.068  -0.141  -0.052  -0.183
148   T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
149   V         1.085   1.109   1.168   1.054   1.082   1.186   1.157   1.186   1.270
150   H         1.085   1.109   1.168   1.294   1.324   1.402   1.157   1.186   1.270
151   G         0.412   0.521   0.169   0.497   0.634   0.144   0.400   0.556  -0.030
152   L        -0.523  -0.598  -0.587  -0.650  -0.753  -0.691  -0.681  -0.779  -0.746
153   K        -1.082  -1.030  -1.066  -0.949  -0.875  -0.956  -1.114  -1.050  -1.026
154   Q        -0.773  -0.770  -0.632  -0.834  -0.842  -0.672  -1.006  -0.995  -0.801
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   P        -0.338  -0.336  -0.544  -0.140  -0.144  -0.491  -0.397  -0.390  -0.683
157   Q        -2.321  -2.214  -2.026  -2.150  -2.005  -1.755  -1.763  -1.655  -1.404
158   G         0.080   0.135   0.084   0.013   0.102  -0.021  -0.141  -0.052  -0.183
159   L        -0.229  -0.283  -0.523  -0.201  -0.253  -0.564  -0.249  -0.319  -0.654
160   K        -1.082  -0.957  -1.050  -1.036  -0.842  -1.052  -1.114  -0.962  -1.010
161   E         0.412   0.299   0.156   0.389   0.258   0.065   0.400   0.222  -0.052
162   S        -0.229  -0.412  -0.540  -0.034  -0.264  -0.450  -0.249  -0.495  -0.676
163   Q        -0.229  -0.412  -0.540   0.016  -0.236  -0.501  -0.249  -0.495  -0.676
164   E        -1.392  -1.541  -1.451  -1.291  -1.510  -1.378  -1.222  -1.355  -1.205
165   F        -0.229  -0.248  -0.522   0.003  -0.019  -0.503  -0.249  -0.270  -0.652
166   P         0.352   0.399   0.150   0.502   0.561   0.180   0.309   0.378  -0.064
167   E        -1.701  -1.608  -1.463  -1.780  -1.657  -1.419  -1.546  -1.443  -1.217
168   P         0.412   0.379   0.153   0.581   0.537   0.184   0.400   0.347  -0.059
169   I         0.080  -0.011   0.047  -0.093  -0.268  -0.212  -0.141  -0.313  -0.253
170   F         0.080   0.005   0.049   0.176   0.051   0.082  -0.141  -0.282  -0.250
171   T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
172   P         1.085   1.109   1.168   1.166   1.194   1.287   1.157   1.186   1.270
173   S         1.085   1.109   1.168   1.078   1.110   1.209   1.157   1.186   1.270
174   T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
175   K         1.085   1.109   1.168   0.925   0.960   1.072   1.157   1.186   1.270
176   A         1.085   1.109   1.168   1.047   1.072   1.181   1.157   1.186   1.270
177   E         0.412   0.340   0.153   0.368   0.281   0.005   0.400   0.287  -0.058
178   Q        -0.229  -0.412  -0.540  -0.010  -0.273  -0.562  -0.249  -0.495  -0.676
179   G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
180   E         0.352   0.204   0.125   0.290   0.088  -0.052   0.309   0.067  -0.109
181   H         1.085   1.109   1.168   1.294   1.324   1.402   1.157   1.186   1.270
182   D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
183   E         1.085   1.109   1.168   0.953   0.989   1.096   1.157   1.186   1.270
184   N         1.085   1.109   1.168   1.229   1.262   1.343   1.157   1.186   1.270
185   I         1.085   1.109   1.168   1.010   1.047   1.147   1.157   1.186   1.270
186   S        -0.229  -0.283  -0.523  -0.042  -0.102  -0.443  -0.249  -0.319  -0.654
187   P        -0.229  -0.248  -0.522  -0.016  -0.043  -0.507  -0.249  -0.270  -0.652
188   A        -0.773  -0.726  -0.632  -1.036  -0.961  -0.823  -1.006  -0.932  -0.802
189   Q        -0.656  -0.696  -0.599  -0.786  -0.866  -0.728  -0.898  -0.925  -0.764
190   A         0.412   0.340   0.153   0.463   0.366   0.087   0.400   0.287  -0.058
191   A        -0.229  -0.283  -0.523  -0.114  -0.190  -0.558  -0.249  -0.319  -0.654
192   E        -0.523  -0.445  -0.573  -0.672  -0.594  -0.734  -0.681  -0.597  -0.727
193   L        -0.097   0.040   0.065  -0.436  -0.168  -0.171  -0.465  -0.219  -0.219
194   V         0.412   0.379   0.153   0.463   0.421   0.075   0.400   0.347  -0.059
195   G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
196   E        -1.701  -1.655  -1.469  -1.730  -1.631  -1.386  -1.546  -1.468  -1.221
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   D        -1.158  -1.207  -1.077  -1.302  -1.348  -1.139  -1.222  -1.232  -1.038
199   L         0.412   0.299   0.156   0.352   0.223   0.036   0.400   0.222  -0.052
200   S        -1.158  -0.971  -1.065  -1.036  -0.824  -0.939  -1.222  -1.018  -1.026
201   R        -1.392  -1.367  -1.429  -1.202  -1.209  -1.274  -1.222  -1.192  -1.186
202   R        -0.833  -0.897  -1.041  -0.556  -0.643  -0.949  -0.789  -0.857  -0.997
203   V        -0.523  -0.453  -0.572  -0.621  -0.514  -0.723  -0.681  -0.582  -0.725
204   A         0.080   0.117   0.064  -0.105  -0.049  -0.152  -0.141  -0.083  -0.221
205   E        -1.158  -1.045  -1.061  -1.359  -1.210  -1.151  -1.222  -1.093  -1.024
206   L        -0.833  -0.843  -1.027  -0.848  -0.856  -1.164  -0.789  -0.793  -0.981
207   A         0.080   0.026   0.050  -0.003  -0.109  -0.088  -0.141  -0.245  -0.247
208   V        -0.656  -0.717  -0.600  -0.867  -0.950  -0.771  -0.898  -0.946  -0.765
209   K        -1.392  -1.306  -1.420  -1.310  -1.182  -1.344  -1.222  -1.115  -1.177
210   L         0.412   0.299   0.156   0.330   0.191  -0.019   0.400   0.222  -0.052
211   Y         1.085   1.109   1.168   1.199   1.230   1.316   1.157   1.186   1.270
212   S        -0.656  -0.682  -0.595  -0.803  -0.835  -0.711  -0.898  -0.902  -0.759
213   K        -0.229  -0.412  -0.540  -0.243  -0.491  -0.697  -0.249  -0.495  -0.676
214   C        -0.097   0.040   0.065  -0.170   0.023   0.076  -0.465  -0.219  -0.219
215   K        -0.773  -0.816  -0.642  -0.987  -1.050  -0.764  -1.006  -1.056  -0.814
216   D        -0.153  -0.116   0.026  -0.528  -0.464  -0.229  -0.573  -0.510  -0.292
217   Y        -0.229  -0.192  -0.519   0.059   0.095  -0.382  -0.249  -0.204  -0.649
218   A         1.085   1.109   1.168   1.047   1.072   1.181   1.157   1.186   1.270
219   K        -1.392  -1.541  -1.451  -1.356  -1.577  -1.460  -1.222  -1.355  -1.205
220   E        -1.392  -1.332  -1.118  -1.663  -1.586  -1.249  -1.438  -1.353  -1.077
221   K        -0.773  -0.746  -0.630  -0.877  -0.820  -0.626  -1.006  -0.966  -0.798
222   G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
223   I         1.085   1.109   1.168   1.010   1.047   1.147   1.157   1.186   1.270
224   I         1.085   1.109   1.168   1.010   1.047   1.147   1.157   1.186   1.270
225   I         1.085   1.109   1.168   1.010   1.047   1.147   1.157   1.186   1.270
226   A         1.085   1.109   1.168   1.047   1.072   1.181   1.157   1.186   1.270
227   D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
228   T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
229   K         1.085   1.109   1.168   0.925   0.960   1.072   1.157   1.186   1.270
230   F         1.085   1.109   1.168   1.195   1.229   1.313   1.157   1.186   1.270
231   E         1.085   1.109   1.168   0.953   0.989   1.096   1.157   1.186   1.270
232   F         1.085   1.109   1.168   1.195   1.229   1.313   1.157   1.186   1.270
233   G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
234   I        -1.158  -1.117  -1.071  -1.320  -1.263  -1.130  -1.222  -1.156  -1.033
235   D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
236   E        -0.338  -0.214  -0.528  -0.390  -0.214  -0.701  -0.397  -0.225  -0.660
237   K        -1.295  -1.301  -1.112  -1.522  -1.551  -1.243  -1.334  -1.324  -1.072
238   T        -0.833  -0.812  -1.027  -0.633  -0.600  -0.923  -0.789  -0.754  -0.981
239   N        -0.656  -0.669  -0.595  -0.667  -0.683  -0.577  -0.898  -0.895  -0.759
240   E        -1.158  -1.148  -1.072  -1.354  -1.315  -1.151  -1.222  -1.177  -1.032
241   I         0.412   0.379   0.153   0.406   0.370   0.003   0.400   0.347  -0.059
242   I        -0.097   0.040   0.065  -0.346  -0.098  -0.089  -0.465  -0.219  -0.219
243   L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
244   V         0.412   0.299   0.156   0.463   0.313   0.082   0.400   0.222  -0.052
245   D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
246   E         1.085   1.109   1.168   0.953   0.989   1.096   1.157   1.186   1.270
247   V         1.085   1.109   1.168   1.054   1.082   1.186   1.157   1.186   1.270
248   L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
249   T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
250   P         1.085   1.109   1.168   1.166   1.194   1.287   1.157   1.186   1.270
251   D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
252   S         1.085   1.109   1.168   1.078   1.110   1.209   1.157   1.186   1.270
253   S         1.085   1.109   1.168   1.078   1.110   1.209   1.157   1.186   1.270
254   R         1.085   1.109   1.168   1.191   1.223   1.309   1.157   1.186   1.270
255   F         1.085   1.109   1.168   1.195   1.229   1.313   1.157   1.186   1.270
256   W         1.085   1.109   1.168   1.292   1.322   1.400   1.157   1.186   1.270
257   N        -0.833  -0.981  -1.040  -0.502  -0.723  -0.887  -0.789  -0.957  -0.995
258   G        -0.097   0.040   0.065  -0.314  -0.082  -0.059  -0.465  -0.219  -0.219
259   A        -1.585  -1.497  -1.453  -1.604  -1.502  -1.444  -1.438  -1.348  -1.209
260   S        -1.894  -1.924  -1.765  -1.640  -1.740  -1.574  -1.546  -1.550  -1.323
261   Y         0.412   0.546   0.168   0.634   0.792   0.289   0.400   0.592  -0.031
262   K        -1.585  -1.495  -1.439  -1.670  -1.522  -1.425  -1.438  -1.324  -1.196
263   V        -0.523  -0.426  -0.562  -0.596  -0.436  -0.692  -0.681  -0.530  -0.710
264   G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
265   E        -0.833  -0.801  -1.015  -0.766  -0.715  -1.006  -0.789  -0.753  -0.968
266   S        -0.833  -0.873  -1.034  -0.631  -0.699  -0.951  -0.789  -0.837  -0.989
267   Q         0.412   0.340   0.153   0.622   0.541   0.248   0.400   0.287  -0.058
268   D         0.412   0.446   0.167   0.430   0.483   0.060   0.400   0.448  -0.032
269   S         1.085   1.109   1.168   1.078   1.110   1.209   1.157   1.186   1.270
270   Y         0.080  -0.011   0.047   0.179   0.023   0.080  -0.141  -0.313  -0.253
271   D         1.085   1.109   1.168   1.029   1.067   1.164   1.157   1.186   1.270
272   K         1.085   1.109   1.168   0.925   0.960   1.072   1.157   1.186   1.270
273   Q         1.085   1.109   1.168   1.191   1.227   1.309   1.157   1.186   1.270
274   F         0.080   0.026   0.050   0.176   0.085   0.085  -0.141  -0.245  -0.247
275   L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
276   R         1.085   1.109   1.168   1.191   1.223   1.309   1.157   1.186   1.270
277   D        -0.153  -0.104   0.033  -0.325  -0.216  -0.019  -0.573  -0.486  -0.279
278   W         1.085   1.109   1.168   1.292   1.322   1.400   1.157   1.186   1.270
279   L         1.085   1.109   1.168   0.915   0.953   1.062   1.157   1.186   1.270
280   T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
281   A        -1.392  -1.357  -1.424  -1.216  -1.193  -1.303  -1.222  -1.178  -1.181
282   N        -0.229  -0.379  -0.538   0.054  -0.157  -0.468  -0.249  -0.450  -0.674
283   K        -1.082  -0.958  -1.050  -1.072  -0.836  -1.013  -1.114  -0.939  -1.007
284   L         0.412   0.446   0.167   0.330   0.382  -0.001   0.400   0.448  -0.032
285   N        -0.773  -0.719  -0.620  -0.917  -0.880  -0.713  -1.006  -0.932  -0.786
286   G        -0.229  -0.412  -0.540  -0.053  -0.293  -0.495  -0.249  -0.495  -0.676
287   V        -0.523  -0.419  -0.555  -0.648  -0.466  -0.656  -0.681  -0.508  -0.699
288   N        -1.585  -1.485  -1.443  -1.446  -1.329  -1.230  -1.438  -1.327  -1.200
289   G        -0.229  -0.343  -0.541  -0.056  -0.194  -0.504  -0.249  -0.399  -0.679
290   V         1.085   1.109   1.168   1.054   1.082   1.186   1.157   1.186   1.270
291   K        -1.275  -1.246  -1.092  -1.500  -1.432  -1.214  -1.330  -1.267  -1.053
292   M         0.412   0.340   0.153   0.710   0.611   0.263   0.400   0.287  -0.058
293   P        -0.229  -0.220  -0.526   0.001   0.010  -0.475  -0.249  -0.234  -0.658
294   Q        -0.656  -0.653  -0.593  -0.774  -0.749  -0.627  -0.898  -0.868  -0.756
295   D        -0.523  -0.544  -0.589  -0.581  -0.650  -0.677  -0.681  -0.730  -0.748
296   I        -0.523  -0.663  -0.602  -0.621  -0.846  -0.777  -0.681  -0.860  -0.765
297   V        -0.656  -0.600  -0.589  -0.814  -0.747  -0.695  -0.898  -0.823  -0.752
298   D        -1.701  -1.611  -1.469  -1.826  -1.696  -1.477  -1.546  -1.436  -1.221
299   R        -1.275  -1.254  -1.102  -1.305  -1.308  -1.066  -1.330  -1.288  -1.063
300   T         0.412   0.476   0.164   0.479   0.557   0.126   0.400   0.492  -0.038
301   R        -0.523  -0.583  -0.572  -0.465  -0.538  -0.588  -0.681  -0.738  -0.724
302   A        -1.585  -1.536  -1.450  -1.526  -1.460  -1.307  -1.438  -1.372  -1.206
303   K         0.412   0.299   0.156   0.361   0.229   0.042   0.400   0.222  -0.052
304   Y         1.085   1.109   1.168   1.199   1.230   1.316   1.157   1.186   1.270
305   I        -0.656  -0.716  -0.597  -0.864  -0.944  -0.763  -0.898  -0.943  -0.761
306   E         1.085   1.109   1.168   0.953   0.989   1.096   1.157   1.186   1.270
307   A         1.085   1.109   1.168   1.047   1.072   1.181   1.157   1.186   1.270
308   Y         0.080   0.069   0.060   0.179   0.157   0.103  -0.141  -0.168  -0.229
309   E         0.412   0.299   0.156   0.350   0.202  -0.035   0.400   0.222  -0.052
310   T        -2.321  -2.220  -2.029  -1.986  -1.862  -1.598  -1.763  -1.661  -1.406
311   L        -0.097  -0.082   0.027  -0.471  -0.445  -0.267  -0.465  -0.445  -0.291
312   T         1.085   1.109   1.168   1.060   1.087   1.192   1.157   1.186   1.270
313   G         1.085   1.109   1.168   1.080   1.115   1.211   1.157   1.186   1.270
314   S        -1.585  -1.471  -1.454  -1.573  -1.446  -1.320  -1.438  -1.328  -1.209
315   K         0.412   0.299   0.156   0.342   0.200  -0.008   0.400   0.222  -0.052
316   W         0.412   0.299   0.156   0.689   0.533   0.251   0.400   0.222  -0.052
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   S        -1.585  -1.569  -1.448  -1.430  -1.431  -1.245  -1.438  -1.397  -1.204
319   H        -2.038  -1.936  -1.769  -1.861  -1.721  -1.473  -1.668  -1.556  -1.326
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P27616
Output conservation file - output/P27616
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
