1     M         1.955   1.960   2.034   2.265   2.274   2.390   2.206   2.215   2.335
2     Q        -1.551  -1.548  -1.481  -1.263  -1.256  -1.152  -1.192  -1.189  -1.092
3     -        -0.438  -0.428  -0.365  -0.653  -0.623  -0.539  -0.626  -0.612  -0.521
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     I        -1.065  -1.061  -0.993  -1.134  -1.116  -1.022  -0.980  -0.975  -0.878
6     V        -0.115  -0.108  -0.190  -0.037  -0.025  -0.164  -0.173  -0.163  -0.276
7     Q        -0.947  -0.923  -0.915  -0.885  -0.846  -0.845  -0.853  -0.825  -0.794
8     I         0.489   0.479   0.533   0.058   0.034   0.107   0.167   0.147   0.218
9     E        -0.115  -0.098  -0.203   0.042   0.063  -0.102  -0.173  -0.148  -0.295
10    Q        -0.438  -0.435  -0.365  -0.545  -0.543  -0.431  -0.626  -0.621  -0.521
11    A        -0.343  -0.350  -0.312  -0.318  -0.331  -0.263  -0.513  -0.518  -0.455
12    P         1.955   1.960   2.034   2.147   2.154   2.272   2.206   2.215   2.335
13    K        -0.115  -0.102  -0.188  -0.088  -0.066  -0.214  -0.173  -0.154  -0.273
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    D         0.865   0.851   0.746   0.884   0.863   0.712   0.847   0.823   0.620
17    Y         0.489   0.495   0.547   0.359   0.374   0.432   0.167   0.177   0.244
18    I         1.955   1.960   2.034   1.835   1.846   1.959   2.206   2.215   2.335
19    S         1.955   1.960   2.034   1.782   1.791   1.905   2.206   2.215   2.335
20    D         0.865   0.851   0.746   0.875   0.854   0.698   0.847   0.823   0.620
21    I         0.865   0.847   0.749   0.789   0.763   0.613   0.847   0.816   0.625
22    K        -0.947  -0.976  -0.935  -0.739  -0.780  -0.702  -0.853  -0.884  -0.816
23    I         0.489   0.495   0.547   0.225   0.234   0.315   0.167   0.177   0.244
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    I        -0.115  -0.105  -0.215  -0.270  -0.246  -0.450  -0.173  -0.158  -0.312
27    P        -0.343  -0.350  -0.312  -0.466  -0.486  -0.408  -0.513  -0.518  -0.455
28    S        -0.947  -0.949  -0.937  -1.143  -1.144  -1.124  -0.853  -0.854  -0.818
29    K        -0.115  -0.104  -0.195  -0.015  -0.002  -0.161  -0.173  -0.158  -0.284
30    S        -0.115  -0.101  -0.184  -0.035   0.004  -0.146  -0.173  -0.153  -0.268
31    L        -0.343  -0.322  -0.301  -0.378  -0.347  -0.319  -0.513  -0.488  -0.443
32    L        -0.115  -0.146  -0.210  -0.279  -0.335  -0.441  -0.173  -0.217  -0.305
33    L        -0.115  -0.146  -0.210  -0.279  -0.335  -0.441  -0.173  -0.217  -0.305
34    I         0.489   0.497   0.547   0.234   0.247   0.313   0.167   0.182   0.246
35    T        -0.115  -0.098  -0.203  -0.228  -0.204  -0.356  -0.173  -0.148  -0.295
36    S        -0.115  -0.150  -0.206  -0.179  -0.223  -0.297  -0.173  -0.221  -0.299
37    W         0.865   0.851   0.746   1.258   1.240   1.082   0.847   0.823   0.620
38    D         0.865   0.847   0.749   0.858   0.834   0.678   0.847   0.816   0.625
39    G         0.865   0.847   0.749   0.951   0.922   0.743   0.847   0.816   0.625
40    S        -0.947  -0.949  -0.937  -0.962  -0.966  -0.922  -0.853  -0.854  -0.818
41    L        -0.115  -0.105  -0.215  -0.279  -0.271  -0.449  -0.173  -0.158  -0.312
42    T        -0.343  -0.322  -0.317  -0.722  -0.698  -0.664  -0.513  -0.488  -0.461
43    V         0.489   0.497   0.547   0.154   0.160   0.243   0.167   0.182   0.246
44    Y         0.489   0.479   0.533   0.495   0.476   0.550   0.167   0.147   0.218
45    K        -1.065  -1.062  -0.993  -1.244  -1.239  -1.132  -0.980  -0.976  -0.878
46    F        -0.310  -0.309  -0.315  -0.105  -0.107  -0.132  -0.449  -0.448  -0.453
47    D         0.730   0.761   0.685   0.586   0.640   0.486   0.613   0.668   0.507
48    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    Q        -0.947  -0.946  -0.923  -0.988  -0.995  -0.951  -0.853  -0.851  -0.803
50    A        -0.343  -0.322  -0.300  -0.648  -0.625  -0.568  -0.513  -0.488  -0.442
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    K        -0.947  -0.953  -0.944  -0.808  -0.817  -0.791  -0.853  -0.859  -0.826
58    N        -0.343  -0.322  -0.317  -0.220  -0.191  -0.183  -0.513  -0.488  -0.461
59    V        -0.947  -0.953  -0.944  -1.003  -1.021  -1.021  -0.853  -0.859  -0.826
60    D        -0.947  -0.919  -0.919  -0.967  -0.911  -0.941  -0.853  -0.820  -0.799
61    L        -0.115  -0.105  -0.215  -0.092  -0.084  -0.202  -0.173  -0.158  -0.312
62    L        -0.115  -0.143  -0.200  -0.267  -0.315  -0.410  -0.173  -0.212  -0.291
63    Q        -1.551  -1.548  -1.481  -1.248  -1.239  -1.136  -1.192  -1.189  -1.092
64    S        -1.551  -1.548  -1.481  -1.429  -1.420  -1.318  -1.192  -1.189  -1.092
65    L         0.489   0.495   0.547   0.195   0.200   0.287   0.167   0.177   0.244
66    R        -0.947  -0.921  -0.933  -0.673  -0.643  -0.640  -0.853  -0.823  -0.814
67    Y        -0.947  -0.953  -0.944  -0.729  -0.728  -0.735  -0.853  -0.859  -0.826
68    K        -1.551  -1.548  -1.481  -1.440  -1.433  -1.329  -1.192  -1.189  -1.092
69    H        -1.551  -1.548  -1.481  -1.310  -1.317  -1.198  -1.192  -1.189  -1.092
70    P        -0.115  -0.143  -0.200  -0.017  -0.069  -0.201  -0.173  -0.212  -0.291
71    L        -0.115  -0.105  -0.215  -0.092  -0.084  -0.202  -0.173  -0.158  -0.312
72    L         0.489   0.480   0.538   0.173   0.157   0.251   0.167   0.149   0.228
73    C         0.489   0.496   0.540   0.257   0.267   0.347   0.167   0.180   0.231
74    C        -0.947  -0.949  -0.937  -0.855  -0.864  -0.875  -0.853  -0.854  -0.818
75    N        -0.947  -0.950  -0.920  -0.761  -0.761  -0.725  -0.853  -0.856  -0.800
76    F        -0.947  -0.948  -0.949  -0.702  -0.708  -0.713  -0.853  -0.854  -0.831
77    I        -0.438  -0.431  -0.365  -0.878  -0.862  -0.765  -0.626  -0.616  -0.521
78    D         0.569   0.607   0.606   0.361   0.429   0.406   0.318   0.388   0.359
79    N        -1.551  -1.548  -1.481  -1.629  -1.629  -1.518  -1.192  -1.189  -1.092
80    T        -0.947  -0.923  -0.915  -0.909  -0.871  -0.869  -0.853  -0.825  -0.794
81    D        -0.343  -0.351  -0.307  -0.462  -0.472  -0.397  -0.513  -0.521  -0.449
82    L        -1.551  -1.548  -1.481  -1.448  -1.436  -1.337  -1.192  -1.189  -1.092
83    Q        -0.343  -0.353  -0.322  -0.502  -0.517  -0.447  -0.513  -0.524  -0.467
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    I        -0.115  -0.105  -0.215  -0.132  -0.115  -0.268  -0.173  -0.158  -0.312
86    Y        -0.115  -0.150  -0.206   0.133   0.081  -0.019  -0.173  -0.221  -0.299
87    V         0.489   0.480   0.538   0.404   0.387   0.478   0.167   0.149   0.228
88    G         1.955   1.960   2.034   2.056   2.064   2.181   2.206   2.215   2.335
89    T        -0.947  -0.921  -0.933  -1.114  -1.084  -1.086  -0.853  -0.823  -0.814
90    V         0.489   0.495   0.547   0.215   0.218   0.290   0.167   0.177   0.244
91    Q         0.489   0.495   0.546   0.278   0.285   0.365   0.167   0.177   0.242
92    G         1.955   1.960   2.034   2.056   2.064   2.181   2.206   2.215   2.335
93    E        -0.947  -0.949  -0.937  -0.856  -0.866  -0.855  -0.853  -0.854  -0.818
94    I        -0.115  -0.146  -0.210  -0.256  -0.310  -0.424  -0.173  -0.217  -0.305
95    L         0.489   0.495   0.547   0.215   0.219   0.307   0.167   0.177   0.244
96    K        -0.947  -0.919  -0.919  -0.885  -0.844  -0.854  -0.853  -0.820  -0.799
97    V        -0.947  -0.953  -0.944  -0.973  -0.986  -0.987  -0.853  -0.859  -0.826
98    D         1.955   1.960   2.034   1.911   1.918   2.035   2.206   2.215   2.335
99    L        -0.947  -0.953  -0.944  -0.835  -0.843  -0.789  -0.853  -0.859  -0.826
100   I         0.865   0.905   0.758   1.000   1.060   0.815   0.847   0.914   0.643
101   G        -0.115  -0.104  -0.195  -0.099  -0.075  -0.246  -0.173  -0.158  -0.284
102   S        -0.947  -0.953  -0.944  -1.093  -1.098  -1.077  -0.853  -0.859  -0.826
103   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   S        -0.947  -0.948  -0.949  -1.036  -1.037  -1.061  -0.853  -0.854  -0.831
105   F        -0.343  -0.324  -0.308  -0.576  -0.556  -0.535  -0.513  -0.490  -0.451
106   Q        -0.947  -0.948  -0.949  -0.879  -0.891  -0.897  -0.853  -0.854  -0.831
107   A        -1.551  -1.548  -1.481  -1.356  -1.349  -1.244  -1.192  -1.189  -1.092
108   L        -0.947  -0.919  -0.919  -0.936  -0.883  -0.898  -0.853  -0.820  -0.799
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   T        -0.115  -0.058  -0.178  -0.079   0.003  -0.168  -0.173  -0.091  -0.259
116   N        -0.947  -0.951  -0.920  -0.864  -0.860  -0.821  -0.853  -0.856  -0.800
117   N        -0.947  -0.951  -0.920  -0.835  -0.830  -0.790  -0.853  -0.856  -0.800
118   E         0.865   0.843   0.745   0.987   0.951   0.773   0.847   0.809   0.619
119   A        -1.551  -1.548  -1.481  -1.497  -1.500  -1.386  -1.192  -1.189  -1.092
120   N        -0.343  -0.322  -0.317  -0.661  -0.632  -0.612  -0.513  -0.488  -0.461
121   L        -0.115  -0.143  -0.200  -0.255  -0.302  -0.394  -0.173  -0.212  -0.291
122   G         0.865   0.900   0.757   0.951   1.005   0.759   0.847   0.906   0.640
123   I         0.865   0.843   0.745   0.789   0.757   0.608   0.847   0.809   0.619
124   C        -0.343  -0.322  -0.317  -0.519  -0.491  -0.456  -0.513  -0.488  -0.461
125   R        -0.947  -0.948  -0.949  -0.742  -0.737  -0.725  -0.853  -0.854  -0.831
126   I         0.489   0.495   0.547   0.058   0.067   0.137   0.167   0.177   0.244
127   C        -0.947  -0.948  -0.949  -0.751  -0.755  -0.732  -0.853  -0.854  -0.831
128   K        -1.551  -1.548  -1.481  -1.402  -1.393  -1.291  -1.192  -1.189  -1.092
129   Y        -0.947  -0.946  -0.923  -0.848  -0.850  -0.790  -0.853  -0.851  -0.803
130   G        -0.947  -0.953  -0.944  -0.845  -0.858  -0.849  -0.853  -0.859  -0.826
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   D        -0.438  -0.431  -0.365  -0.664  -0.663  -0.549  -0.626  -0.616  -0.521
137   D        -0.343  -0.351  -0.310  -0.393  -0.409  -0.342  -0.513  -0.521  -0.453
138   K        -1.551  -1.548  -1.481  -1.544  -1.537  -1.434  -1.192  -1.189  -1.092
139   L        -0.343  -0.347  -0.306  -0.695  -0.702  -0.626  -0.513  -0.516  -0.448
140   I        -0.115  -0.105  -0.215  -0.148  -0.134  -0.288  -0.173  -0.158  -0.312
141   A         1.955   1.960   2.034   2.132   2.147   2.257   2.206   2.215   2.335
142   A        -0.115  -0.098  -0.203  -0.184  -0.159  -0.300  -0.173  -0.148  -0.295
143   S         0.865   0.900   0.757   0.709   0.762   0.537   0.847   0.906   0.640
144   W         0.489   0.495   0.547   0.600   0.609   0.680   0.167   0.177   0.244
145   D         0.489   0.495   0.547   0.235   0.250   0.320   0.167   0.177   0.244
146   G         1.955   1.960   2.034   2.056   2.064   2.181   2.206   2.215   2.335
147   L        -0.343  -0.322  -0.317  -0.684  -0.655  -0.653  -0.513  -0.488  -0.461
148   I         0.489   0.497   0.547   0.048   0.061   0.131   0.167   0.182   0.246
149   E        -0.947  -0.948  -0.949  -0.802  -0.811  -0.810  -0.853  -0.854  -0.831
150   V        -0.115  -0.105  -0.215  -0.063  -0.058  -0.242  -0.173  -0.158  -0.312
151   I        -0.115  -0.146  -0.210  -0.256  -0.311  -0.424  -0.173  -0.217  -0.305
152   D         0.865   0.851   0.746   0.858   0.840   0.673   0.847   0.823   0.620
153   P        -0.343  -0.353  -0.322  -0.249  -0.260  -0.199  -0.513  -0.524  -0.467
154   R        -0.115  -0.146  -0.210   0.000  -0.057  -0.186  -0.173  -0.217  -0.305
155   N        -1.551  -1.548  -1.481  -1.473  -1.465  -1.362  -1.192  -1.189  -1.092
156   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   D        -0.310  -0.302  -0.298  -0.314  -0.284  -0.303  -0.449  -0.439  -0.429
159   G        -0.947  -0.923  -0.915  -1.000  -0.970  -0.938  -0.853  -0.825  -0.794
160   V        -1.551  -1.548  -1.481  -1.506  -1.520  -1.396  -1.192  -1.189  -1.092
161   I        -0.947  -0.976  -0.935  -0.933  -0.975  -0.895  -0.853  -0.884  -0.816
162   A        -1.551  -1.548  -1.481  -1.406  -1.402  -1.295  -1.192  -1.189  -1.092
163   V        -0.947  -0.919  -0.919  -0.902  -0.854  -0.869  -0.853  -0.820  -0.799
164   K        -1.551  -1.548  -1.481  -1.314  -1.313  -1.202  -1.192  -1.189  -1.092
165   N        -0.115  -0.098  -0.203  -0.037  -0.007  -0.174  -0.173  -0.148  -0.295
166   L         0.865   0.843   0.745   0.772   0.738   0.602   0.847   0.809   0.619
167   N        -0.947  -0.948  -0.949  -0.972  -0.967  -0.945  -0.853  -0.854  -0.831
168   S         0.569   0.530   0.577   0.386   0.325   0.401   0.318   0.244   0.303
169   N        -0.438  -0.431  -0.365  -0.534  -0.523  -0.419  -0.626  -0.616  -0.521
170   N        -0.438  -0.431  -0.365  -0.505  -0.494  -0.390  -0.626  -0.616  -0.521
171   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   N        -0.947  -0.976  -0.935  -0.823  -0.860  -0.797  -0.853  -0.884  -0.816
176   K         1.955   1.960   2.034   1.975   1.983   2.099   2.206   2.215   2.335
177   I         0.865   0.851   0.746   0.840   0.824   0.685   0.847   0.823   0.620
178   F         1.955   1.960   2.034   2.082   2.089   2.206   2.206   2.215   2.335
179   T        -0.947  -0.951  -0.920  -0.751  -0.762  -0.705  -0.853  -0.856  -0.800
180   M         0.489   0.480   0.538   0.437   0.407   0.481   0.167   0.149   0.228
181   D        -0.115  -0.146  -0.210  -0.123  -0.173  -0.275  -0.173  -0.217  -0.305
182   T        -0.115  -0.146  -0.210   0.048   0.003  -0.098  -0.173  -0.217  -0.305
183   N        -0.947  -0.919  -0.919  -1.029  -0.985  -0.975  -0.853  -0.820  -0.799
184   S        -0.947  -0.976  -0.935  -1.011  -1.050  -0.974  -0.853  -0.884  -0.816
185   S        -1.551  -1.548  -1.481  -1.330  -1.324  -1.218  -1.192  -1.189  -1.092
186   R        -0.343  -0.349  -0.318  -0.257  -0.266  -0.220  -0.513  -0.519  -0.463
187   L         0.865   0.843   0.745   0.754   0.718   0.575   0.847   0.809   0.619
188   I        -0.947  -0.951  -0.920  -0.975  -0.980  -0.924  -0.853  -0.856  -0.800
189   V        -0.947  -0.976  -0.935  -0.939  -0.996  -0.931  -0.853  -0.884  -0.816
190   G         0.489   0.480   0.538   0.243   0.218   0.294   0.167   0.149   0.228
191   M        -0.343  -0.347  -0.306  -0.367  -0.390  -0.311  -0.513  -0.516  -0.448
192   N        -0.947  -0.946  -0.923  -1.121  -1.117  -1.080  -0.853  -0.851  -0.803
193   N        -0.947  -0.951  -0.920  -0.975  -0.979  -0.942  -0.853  -0.856  -0.800
194   S        -1.551  -1.548  -1.481  -1.354  -1.339  -1.242  -1.192  -1.189  -1.092
195   Q        -0.947  -0.921  -0.933  -1.044  -1.002  -1.039  -0.853  -0.823  -0.814
196   V         0.489   0.495   0.546   0.183   0.190   0.269   0.167   0.177   0.242
197   Q        -0.947  -0.948  -0.949  -0.745  -0.750  -0.750  -0.853  -0.854  -0.831
198   W        -0.115  -0.104  -0.195  -0.166  -0.158  -0.282  -0.173  -0.158  -0.284
199   F        -0.343  -0.353  -0.322  -0.326  -0.342  -0.305  -0.513  -0.524  -0.467
200   R        -0.947  -0.948  -0.949  -0.899  -0.908  -0.888  -0.853  -0.854  -0.831
201   L        -0.343  -0.324  -0.308  -0.425  -0.403  -0.338  -0.513  -0.490  -0.451
202   P        -0.115  -0.105  -0.215   0.126   0.137  -0.041  -0.173  -0.158  -0.312
203   L        -0.343  -0.353  -0.322  -0.665  -0.677  -0.643  -0.513  -0.524  -0.467
204   C        -0.947  -0.946  -0.923  -0.638  -0.647  -0.614  -0.853  -0.851  -0.803
205   E        -1.551  -1.548  -1.481  -1.239  -1.231  -1.127  -1.192  -1.189  -1.092
206   D        -1.551  -1.548  -1.481  -1.378  -1.373  -1.266  -1.192  -1.189  -1.092
207   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   N        -0.310  -0.309  -0.315  -0.275  -0.276  -0.315  -0.449  -0.448  -0.453
209   G        -1.065  -1.062  -0.993  -0.988  -0.990  -0.875  -0.980  -0.976  -0.878
210   T        -0.947  -0.949  -0.937  -0.689  -0.691  -0.660  -0.853  -0.854  -0.818
211   I        -0.947  -0.953  -0.944  -0.962  -0.971  -0.939  -0.853  -0.859  -0.826
212   E        -0.947  -0.948  -0.949  -0.819  -0.829  -0.839  -0.853  -0.854  -0.831
213   E        -0.115  -0.143  -0.200   0.041  -0.009  -0.109  -0.173  -0.212  -0.291
214   S         0.865   0.847   0.749   0.735   0.709   0.562   0.847   0.816   0.625
215   G         1.955   1.960   2.034   2.056   2.064   2.181   2.206   2.215   2.335
216   L         0.865   0.851   0.746   0.768   0.744   0.595   0.847   0.823   0.620
217   K         0.865   0.851   0.746   0.883   0.862   0.678   0.847   0.823   0.620
218   Y         0.865   0.851   0.746   1.119   1.103   0.939   0.847   0.823   0.620
219   Q         1.955   1.960   2.034   2.063   2.070   2.188   2.206   2.215   2.335
220   I         0.865   0.843   0.745   0.840   0.813   0.685   0.847   0.809   0.619
221   R         0.489   0.495   0.547   0.402   0.410   0.482   0.167   0.177   0.244
222   D         0.865   0.843   0.745   0.806   0.770   0.596   0.847   0.809   0.619
223   V        -0.947  -0.948  -0.949  -1.050  -1.058  -1.039  -0.853  -0.854  -0.831
224   A        -0.947  -0.948  -0.949  -0.811  -0.815  -0.801  -0.853  -0.854  -0.831
225   L        -0.115  -0.105  -0.215  -0.217  -0.200  -0.367  -0.173  -0.158  -0.312
226   L        -0.947  -0.948  -0.949  -0.951  -0.955  -0.987  -0.853  -0.854  -0.831
227   P         1.955   1.960   2.034   2.147   2.154   2.272   2.206   2.215   2.335
228   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   E        -0.947  -0.953  -0.944  -0.835  -0.846  -0.844  -0.853  -0.859  -0.826
230   Q        -0.343  -0.322  -0.301  -0.381  -0.347  -0.308  -0.513  -0.488  -0.443
231   E        -0.947  -0.976  -0.935  -0.777  -0.830  -0.763  -0.853  -0.884  -0.816
232   G         1.955   1.960   2.034   2.056   2.064   2.181   2.206   2.215   2.335
233   Y         0.865   0.905   0.758   1.066   1.122   0.916   0.847   0.914   0.643
234   A         0.489   0.480   0.538   0.438   0.418   0.500   0.167   0.149   0.228
235   C        -0.947  -0.953  -0.944  -0.833  -0.848  -0.866  -0.853  -0.859  -0.826
236   S        -0.115  -0.146  -0.210  -0.213  -0.259  -0.347  -0.173  -0.217  -0.305
237   S        -0.115  -0.143  -0.200  -0.213  -0.254  -0.333  -0.173  -0.212  -0.291
238   I         0.865   0.843   0.745   0.789   0.757   0.608   0.847   0.809   0.619
239   D         1.955   1.960   2.034   1.911   1.918   2.035   2.206   2.215   2.335
240   G         1.955   1.960   2.034   2.056   2.064   2.181   2.206   2.215   2.335
241   R         1.955   1.960   2.034   2.114   2.122   2.239   2.206   2.215   2.335
242   V         1.955   1.960   2.034   2.012   2.015   2.136   2.206   2.215   2.335
243   A         0.489   0.514   0.551   0.209   0.248   0.308   0.167   0.213   0.252
244   V        -0.115  -0.105  -0.215   0.006   0.022  -0.150  -0.173  -0.158  -0.312
245   E         1.955   1.960   2.034   2.093   2.100   2.217   2.206   2.215   2.335
246   F         0.489   0.495   0.546   0.495   0.507   0.576   0.167   0.177   0.242
247   F         1.955   1.960   2.034   2.082   2.089   2.206   2.206   2.215   2.335
248   D         0.865   0.847   0.749   0.858   0.834   0.678   0.847   0.816   0.625
249   D         0.489   0.495   0.547   0.327   0.333   0.419   0.167   0.177   0.244
250   Q        -0.438  -0.431  -0.365  -0.587  -0.574  -0.472  -0.626  -0.616  -0.521
251   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   D        -0.438  -0.431  -0.365  -0.491  -0.493  -0.376  -0.626  -0.616  -0.521
253   D        -0.438  -0.431  -0.365  -0.547  -0.549  -0.433  -0.626  -0.616  -0.521
254   Y        -0.438  -0.431  -0.365  -0.530  -0.502  -0.415  -0.626  -0.616  -0.521
255   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   S        -0.947  -0.946  -0.923  -0.989  -0.990  -0.972  -0.853  -0.851  -0.803
257   S         0.865   0.847   0.749   0.749   0.724   0.581   0.847   0.816   0.625
258   K        -0.115  -0.150  -0.206  -0.019  -0.068  -0.155  -0.173  -0.221  -0.299
259   R         0.489   0.494   0.539   0.402   0.407   0.465   0.167   0.174   0.230
260   F         1.955   1.960   2.034   2.082   2.089   2.206   2.206   2.215   2.335
261   A         0.865   0.847   0.749   1.089   1.069   0.910   0.847   0.816   0.625
262   F         1.955   1.960   2.034   2.082   2.089   2.206   2.206   2.215   2.335
263   R         0.489   0.495   0.547   0.402   0.410   0.482   0.167   0.177   0.244
264   C         1.955   1.960   2.034   2.211   2.220   2.337   2.206   2.215   2.335
265   H         1.955   1.960   2.034   2.251   2.259   2.376   2.206   2.215   2.335
266   R         0.865   0.851   0.746   1.054   1.033   0.863   0.847   0.823   0.620
267   L        -1.551  -1.548  -1.481  -1.159  -1.142  -1.047  -1.192  -1.189  -1.092
268   N        -0.947  -0.949  -0.937  -0.962  -0.953  -0.958  -0.853  -0.854  -0.818
269   L         0.489   0.495   0.547   0.093   0.098   0.178   0.167   0.177   0.244
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   K        -0.947  -0.948  -0.949  -1.081  -1.085  -1.070  -0.853  -0.854  -0.831
275   D        -0.115  -0.105  -0.215  -0.060  -0.045  -0.200  -0.173  -0.158  -0.312
276   T        -0.115  -0.150  -0.206   0.025  -0.030  -0.122  -0.173  -0.221  -0.299
277   N        -0.947  -0.948  -0.949  -0.936  -0.938  -0.931  -0.853  -0.854  -0.831
278   L         0.489   0.480   0.538   0.305   0.293   0.396   0.167   0.149   0.228
279   A        -0.115  -0.098  -0.203   0.028   0.049  -0.103  -0.173  -0.148  -0.295
280   Y         0.865   0.843   0.745   1.119   1.092   0.938   0.847   0.809   0.619
281   P         1.955   1.960   2.034   2.147   2.154   2.272   2.206   2.215   2.335
282   V         0.489   0.496   0.538   0.234   0.243   0.291   0.167   0.179   0.228
283   N         0.865   0.843   0.745   0.949   0.930   0.769   0.847   0.809   0.619
284   S         0.489   0.480   0.538   0.209   0.201   0.293   0.167   0.149   0.228
285   I         0.489   0.479   0.533   0.058   0.034   0.107   0.167   0.147   0.218
286   E        -0.947  -0.946  -0.923  -0.733  -0.735  -0.700  -0.853  -0.851  -0.803
287   F         1.955   1.960   2.034   2.082   2.089   2.206   2.206   2.215   2.335
288   S        -0.947  -0.948  -0.949  -1.031  -1.021  -1.058  -0.853  -0.854  -0.831
289   P        -0.115  -0.105  -0.215   0.168   0.185   0.015  -0.173  -0.158  -0.312
290   R        -0.947  -0.921  -0.933  -0.838  -0.794  -0.812  -0.853  -0.823  -0.814
291   H        -1.551  -1.548  -1.481  -1.319  -1.316  -1.207  -1.192  -1.189  -1.092
292   K        -1.551  -1.548  -1.481  -1.648  -1.647  -1.537  -1.192  -1.189  -1.092
293   F        -0.947  -0.948  -0.949  -0.786  -0.786  -0.787  -0.853  -0.854  -0.831
294   L         0.865   0.851   0.746   0.772   0.750   0.602   0.847   0.823   0.620
295   Y         0.489   0.497   0.547   0.474   0.489   0.563   0.167   0.182   0.246
296   T         1.955   1.960   2.034   2.045   2.057   2.170   2.206   2.215   2.335
297   A         0.489   0.480   0.538   0.462   0.446   0.527   0.167   0.149   0.228
298   G         1.955   1.960   2.034   2.056   2.064   2.181   2.206   2.215   2.335
299   S         0.865   0.843   0.745   0.767   0.739   0.603   0.847   0.809   0.619
300   D         1.955   1.960   2.034   1.911   1.918   2.035   2.206   2.215   2.335
301   G         1.955   1.960   2.034   2.056   2.064   2.181   2.206   2.215   2.335
302   I        -0.947  -0.948  -0.949  -0.752  -0.748  -0.771  -0.853  -0.854  -0.831
303   I        -0.343  -0.324  -0.304  -0.616  -0.589  -0.555  -0.513  -0.491  -0.446
304   S        -0.343  -0.353  -0.322  -0.430  -0.446  -0.393  -0.513  -0.524  -0.467
305   C        -1.551  -1.548  -1.481  -1.330  -1.346  -1.218  -1.192  -1.189  -1.092
306   W         1.955   1.960   2.034   2.279   2.288   2.404   2.206   2.215   2.335
307   N        -0.115  -0.143  -0.200   0.004  -0.029  -0.122  -0.173  -0.212  -0.291
308   L        -0.115  -0.105  -0.215  -0.066  -0.057  -0.169  -0.173  -0.158  -0.312
309   Q        -0.947  -0.976  -0.935  -0.741  -0.792  -0.717  -0.853  -0.884  -0.816
310   T         0.489   0.495   0.546   0.322   0.333   0.406   0.167   0.177   0.242
311   R         0.865   0.851   0.746   1.054   1.033   0.863   0.847   0.823   0.620
312   K         0.865   0.851   0.746   0.934   0.915   0.755   0.847   0.823   0.620
313   K         0.489   0.495   0.547   0.362   0.370   0.451   0.167   0.177   0.244
314   I        -0.115  -0.150  -0.206  -0.087  -0.134  -0.196  -0.173  -0.221  -0.299
315   K        -0.115  -0.150  -0.206   0.003  -0.050  -0.127  -0.173  -0.221  -0.299
316   N        -0.115  -0.104  -0.195   0.046   0.064  -0.084  -0.173  -0.158  -0.284
317   F        -0.115  -0.143  -0.200   0.026  -0.021  -0.124  -0.173  -0.212  -0.291
318   A        -0.115  -0.104  -0.195   0.215   0.232   0.106  -0.173  -0.158  -0.284
319   K         0.489   0.495   0.547   0.362   0.370   0.451   0.167   0.177   0.244
320   F        -0.115  -0.146  -0.210   0.026  -0.028  -0.141  -0.173  -0.217  -0.305
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   N         0.730   0.711   0.671   0.706   0.677   0.609   0.613   0.578   0.482
327   E        -0.947  -0.953  -0.944  -0.771  -0.785  -0.771  -0.853  -0.859  -0.826
328   D        -0.947  -0.949  -0.937  -0.902  -0.904  -0.876  -0.853  -0.854  -0.818
329   S         0.865   0.843   0.745   0.744   0.714   0.569   0.847   0.809   0.619
330   V         0.489   0.497   0.547   0.183   0.195   0.272   0.167   0.182   0.246
331   V         0.865   0.843   0.745   1.026   0.992   0.871   0.847   0.809   0.619
332   K         0.865   0.851   0.746   0.939   0.919   0.762   0.847   0.823   0.620
333   I        -0.115  -0.058  -0.178  -0.267  -0.181  -0.372  -0.173  -0.091  -0.259
334   A        -0.947  -0.953  -0.944  -0.741  -0.745  -0.744  -0.853  -0.859  -0.826
335   C         0.489   0.495   0.547   0.409   0.420   0.481   0.167   0.177   0.244
336   S        -0.343  -0.352  -0.304  -0.582  -0.575  -0.505  -0.513  -0.521  -0.446
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   D        -0.343  -0.324  -0.306  -0.436  -0.405  -0.376  -0.513  -0.491  -0.448
340   N        -0.115  -0.108  -0.190  -0.085  -0.065  -0.218  -0.173  -0.163  -0.276
341   I        -0.343  -0.353  -0.322  -0.640  -0.651  -0.579  -0.513  -0.524  -0.467
342   L        -0.115  -0.105  -0.215  -0.192  -0.175  -0.334  -0.173  -0.158  -0.312
343   C        -0.343  -0.324  -0.308  -0.260  -0.242  -0.205  -0.513  -0.490  -0.451
344   L        -0.343  -0.322  -0.300  -0.616  -0.585  -0.551  -0.513  -0.488  -0.442
345   A         1.955   1.960   2.034   2.132   2.147   2.257   2.206   2.215   2.335
346   T         0.865   0.843   0.745   0.995   0.965   0.809   0.847   0.809   0.619
347   S         1.955   1.960   2.034   1.782   1.791   1.905   2.206   2.215   2.335
348   D         1.955   1.960   2.034   1.911   1.918   2.035   2.206   2.215   2.335
349   D         1.955   1.960   2.034   1.911   1.918   2.035   2.206   2.215   2.335
350   T        -0.115  -0.101  -0.184  -0.235  -0.210  -0.337  -0.173  -0.153  -0.268
351   F         0.489   0.495   0.547   0.474   0.485   0.562   0.167   0.177   0.244
352   K         1.955   1.960   2.034   1.975   1.983   2.099   2.206   2.215   2.335
353   T        -0.115  -0.105  -0.215   0.036   0.058  -0.123  -0.173  -0.158  -0.312
354   N        -0.947  -0.953  -0.944  -0.829  -0.822  -0.817  -0.853  -0.859  -0.826
355   A        -0.115  -0.105  -0.215   0.113   0.134  -0.053  -0.173  -0.158  -0.312
356   A        -1.065  -1.062  -0.993  -1.016  -1.009  -0.903  -0.980  -0.976  -0.878
357   I        -0.343  -0.353  -0.322  -0.695  -0.713  -0.647  -0.513  -0.524  -0.467
358   D        -0.343  -0.353  -0.322  -0.601  -0.614  -0.541  -0.513  -0.524  -0.467
359   Q        -0.947  -0.949  -0.937  -0.969  -0.976  -0.978  -0.853  -0.854  -0.818
360   T        -0.947  -0.948  -0.949  -1.096  -1.096  -1.087  -0.853  -0.854  -0.831
361   I        -0.947  -0.949  -0.937  -1.007  -1.017  -0.980  -0.853  -0.854  -0.818
362   E         0.489   0.495   0.547   0.391   0.406   0.472   0.167   0.177   0.244
363   L        -0.115  -0.105  -0.215  -0.228  -0.223  -0.381  -0.173  -0.158  -0.312
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   N        -1.551  -1.548  -1.481  -1.258  -1.242  -1.146  -1.192  -1.189  -1.092
366   A         0.865   0.905   0.758   1.124   1.181   0.970   0.847   0.914   0.643
367   S         1.955   1.960   2.034   1.782   1.791   1.905   2.206   2.215   2.335
368   S        -0.947  -0.923  -0.915  -0.838  -0.790  -0.797  -0.853  -0.825  -0.794
369   I         0.865   0.847   0.749   0.789   0.763   0.613   0.847   0.816   0.625
370   Y         1.955   1.960   2.034   2.154   2.167   2.279   2.206   2.215   2.335
371   I         0.489   0.481   0.532   0.183   0.167   0.249   0.167   0.151   0.217
372   I        -0.115  -0.098  -0.203  -0.085  -0.055  -0.236  -0.173  -0.148  -0.295
373   F        -1.551  -1.548  -1.481  -1.423  -1.414  -1.312  -1.192  -1.189  -1.092
374   D         0.865   0.905   0.758   0.729   0.784   0.558   0.847   0.914   0.643
375   Y        -0.438  -0.431  -0.365  -0.391  -0.376  -0.276  -0.626  -0.616  -0.521
376   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   N         0.730   0.711   0.671   0.617   0.584   0.490   0.613   0.578   0.482
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P26449
Output conservation file - output/P26449
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
