1     M         0.917   0.936   0.963   1.153   1.174   1.203   0.961   0.981   1.018
2     F        -0.108  -0.004  -0.278  -0.128   0.025  -0.386  -0.193  -0.034  -0.468
3     K        -1.243  -1.138  -1.121  -1.448  -1.256  -1.206  -1.347  -1.198  -1.136
4     R        -1.811  -1.800  -1.691  -1.640  -1.628  -1.482  -1.636  -1.589  -1.429
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.332  -1.274  -1.144  -1.517  -1.409  -1.196  -1.443  -1.342  -1.160
13    S        -1.212  -1.187  -1.128  -1.217  -1.183  -1.101  -1.293  -1.243  -1.142
14    I        -1.243  -1.116  -1.122  -1.425  -1.220  -1.199  -1.347  -1.166  -1.136
15    I        -2.378  -2.261  -2.123  -2.307  -2.116  -1.906  -1.924  -1.779  -1.596
16    Q        -2.378  -2.261  -2.123  -2.161  -2.073  -1.774  -1.924  -1.779  -1.596
17    Q        -1.029  -1.071  -1.110  -0.806  -0.890  -0.984  -1.059  -1.103  -1.120
18    S        -2.378  -2.261  -2.123  -2.208  -1.982  -1.817  -1.924  -1.779  -1.596
19    R        -0.108  -0.275  -0.313   0.106  -0.156  -0.260  -0.193  -0.452  -0.527
20    L        -0.108  -0.004  -0.278  -0.050   0.099  -0.346  -0.193  -0.034  -0.468
21    F        -0.108  -0.004  -0.278  -0.128   0.025  -0.386  -0.193  -0.034  -0.468
22    S        -0.108  -0.275  -0.313  -0.036  -0.288  -0.366  -0.193  -0.452  -0.527
23    N        -1.029  -1.027  -1.105  -0.901  -0.891  -0.991  -1.059  -1.055  -1.114
24    S        -0.108  -0.004  -0.278  -0.058   0.103  -0.342  -0.193  -0.034  -0.468
25    A        -0.108  -0.004  -0.278  -0.008   0.147  -0.294  -0.193  -0.034  -0.468
26    S        -2.378  -2.261  -2.123  -2.128  -1.945  -1.745  -1.924  -1.779  -1.596
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    R        -1.811  -1.639  -1.667  -1.802  -1.541  -1.540  -1.636  -1.425  -1.407
33    L        -1.029  -1.147  -1.123  -0.880  -1.071  -0.998  -1.059  -1.191  -1.136
34    G        -1.029  -1.071  -1.110  -1.282  -1.354  -1.310  -1.059  -1.103  -1.120
35    K        -1.243  -1.269  -1.132  -1.405  -1.367  -1.149  -1.347  -1.336  -1.148
36    K         0.917   0.936   0.963   0.810   0.844   0.894   0.961   0.981   1.018
37    V         0.917   0.936   0.963   0.941   0.973   1.012   0.961   0.981   1.018
38    F        -0.461  -0.458  -0.366  -0.604  -0.576  -0.413  -0.770  -0.759  -0.616
39    F        -0.108  -0.102  -0.293  -0.136  -0.119  -0.426  -0.193  -0.179  -0.493
40    D        -1.029  -0.948  -1.084  -0.933  -0.787  -1.053  -1.059  -0.936  -1.090
41    P        -1.029  -1.071  -1.110  -0.910  -0.986  -1.080  -1.059  -1.103  -1.120
42    A        -1.029  -1.027  -1.105  -0.981  -0.993  -1.108  -1.059  -1.055  -1.114
43    V        -1.243  -1.269  -1.132  -1.314  -1.297  -1.089  -1.347  -1.336  -1.148
44    N        -0.461  -0.464  -0.365  -0.768  -0.833  -0.664  -0.770  -0.768  -0.614
45    G        -0.108  -0.275  -0.313  -0.373  -0.606  -0.622  -0.193  -0.452  -0.527
46    T        -2.378  -2.261  -2.123  -2.368  -2.189  -1.961  -1.924  -1.779  -1.596
47    K        -1.029  -1.080  -1.109  -1.040  -1.097  -1.100  -1.059  -1.113  -1.119
48    I        -1.811  -1.800  -1.691  -1.640  -1.625  -1.420  -1.636  -1.589  -1.429
49    G        -1.029  -0.938  -1.096  -1.293  -1.149  -1.312  -1.059  -0.924  -1.104
50    R        -0.108  -0.102  -0.293   0.125   0.148  -0.185  -0.193  -0.179  -0.493
51    I         0.917   0.936   0.963   0.941   0.970   1.012   0.961   0.981   1.018
52    E        -1.029  -1.147  -1.123  -1.063  -1.242  -1.242  -1.059  -1.191  -1.136
53    F        -0.108  -0.275  -0.313  -0.082  -0.312  -0.356  -0.193  -0.452  -0.527
54    E        -0.108  -0.275  -0.313  -0.162  -0.454  -0.582  -0.193  -0.452  -0.527
55    L         0.917   0.936   0.963   0.972   0.988   1.040   0.961   0.981   1.018
56    Y         0.917   0.936   0.963   1.153   1.174   1.203   0.961   0.981   1.018
57    D        -0.108  -0.275  -0.313  -0.052  -0.353  -0.491  -0.193  -0.452  -0.527
58    N        -1.811  -1.773  -1.686  -1.762  -1.727  -1.585  -1.636  -1.567  -1.424
59    V        -1.029  -1.071  -1.110  -1.014  -1.092  -1.157  -1.059  -1.103  -1.120
60    V         0.917   0.936   0.963   0.941   0.973   1.012   0.961   0.981   1.018
61    P         0.917   0.936   0.963   1.051   1.085   1.111   0.961   0.981   1.018
62    K         0.917   0.936   0.963   0.810   0.844   0.894   0.961   0.981   1.018
63    T         0.917   0.936   0.963   0.910   0.933   0.985   0.961   0.981   1.018
64    A        -0.108  -0.102  -0.293  -0.015  -0.004  -0.335  -0.193  -0.179  -0.493
65    E         0.917   0.936   0.963   0.922   0.965   0.996   0.961   0.981   1.018
66    N         0.917   0.936   0.963   1.039   1.075   1.100   0.961   0.981   1.018
67    F         0.917   0.936   0.963   0.866   0.894   0.945   0.961   0.981   1.018
68    R         0.917   0.936   0.963   1.105   1.137   1.160   0.961   0.981   1.018
69    A         0.917   0.936   0.963   0.996   1.020   1.062   0.961   0.981   1.018
70    L         0.917   0.936   0.963   0.972   0.988   1.040   0.961   0.981   1.018
71    C        -0.108  -0.275  -0.313   0.233  -0.033  -0.152  -0.193  -0.452  -0.527
72    T         0.917   0.936   0.963   0.910   0.933   0.985   0.961   0.981   1.018
73    G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
74    E         0.917   0.936   0.963   0.922   0.965   0.996   0.961   0.981   1.018
75    K         0.917   0.936   0.963   0.810   0.844   0.894   0.961   0.981   1.018
76    G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
77    W        -0.461  -0.345  -0.333  -0.552  -0.376  -0.336  -0.770  -0.567  -0.559
78    G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
79    Y         0.917   0.936   0.963   1.153   1.174   1.203   0.961   0.981   1.018
80    K        -1.029  -1.147  -1.123  -1.117  -1.287  -1.233  -1.059  -1.191  -1.136
81    G        -0.108  -0.102  -0.293  -0.371  -0.352  -0.591  -0.193  -0.179  -0.493
82    V        -0.461  -0.464  -0.365  -0.657  -0.655  -0.493  -0.770  -0.768  -0.614
83    P        -1.029  -1.147  -1.123  -0.910  -1.113  -1.106  -1.059  -1.191  -1.136
84    F         0.917   0.936   0.963   0.866   0.894   0.945   0.961   0.981   1.018
85    H         0.917   0.936   0.963   1.194   1.213   1.240   0.961   0.981   1.018
86    R         0.917   0.936   0.963   1.105   1.137   1.160   0.961   0.981   1.018
87    I        -0.461  -0.464  -0.365  -0.664  -0.665  -0.502  -0.770  -0.768  -0.614
88    I         0.917   0.936   0.963   0.941   0.970   1.012   0.961   0.981   1.018
89    P        -0.108  -0.275  -0.313   0.015  -0.259  -0.379  -0.193  -0.452  -0.527
90    D        -1.243  -1.108  -1.121  -1.149  -0.934  -0.950  -1.347  -1.172  -1.136
91    F         0.917   0.936   0.963   0.866   0.894   0.945   0.961   0.981   1.018
92    M         0.917   0.936   0.963   1.153   1.174   1.203   0.961   0.981   1.018
93    I        -0.461  -0.407  -0.358  -0.646  -0.547  -0.469  -0.770  -0.671  -0.602
94    Q         0.917   0.936   0.963   1.135   1.155   1.187   0.961   0.981   1.018
95    G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
96    G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
97    D         0.917   0.936   0.963   1.033   1.067   1.095   0.961   0.981   1.018
98    T        -0.461  -0.464  -0.365  -0.733  -0.751  -0.572  -0.770  -0.768  -0.614
99    D        -1.029  -1.147  -1.123  -0.933  -1.129  -1.127  -1.059  -1.191  -1.136
100   L        -1.029  -1.147  -1.123  -1.026  -1.253  -1.223  -1.059  -1.191  -1.136
101   T        -0.461  -0.464  -0.365  -0.884  -0.946  -0.752  -0.770  -0.768  -0.614
102   N        -1.029  -1.147  -1.123  -0.924  -1.100  -1.117  -1.059  -1.191  -1.136
103   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
104   F        -1.243  -1.269  -1.132  -1.295  -1.317  -1.104  -1.347  -1.336  -1.148
105   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
106   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
107   K        -0.108  -0.102  -0.293  -0.150  -0.123  -0.394  -0.193  -0.179  -0.493
108   S         0.917   0.936   0.963   0.953   0.984   1.023   0.961   0.981   1.018
109   I         0.917   0.936   0.963   0.941   0.970   1.012   0.961   0.981   1.018
110   Y         0.917   0.936   0.963   1.153   1.174   1.203   0.961   0.981   1.018
111   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
112   S        -1.811  -1.773  -1.686  -1.618  -1.539  -1.425  -1.636  -1.567  -1.424
113   K         0.917   0.936   0.963   0.810   0.844   0.894   0.961   0.981   1.018
114   F         0.917   0.936   0.963   0.866   0.894   0.945   0.961   0.981   1.018
115   A        -1.029  -1.147  -1.123  -0.914  -1.089  -1.069  -1.059  -1.191  -1.136
116   D         0.917   0.936   0.963   1.033   1.067   1.095   0.961   0.981   1.018
117   E         0.917   0.936   0.963   0.922   0.965   0.996   0.961   0.981   1.018
118   N         0.917   0.936   0.963   1.039   1.075   1.100   0.961   0.981   1.018
119   F         0.917   0.936   0.963   0.866   0.894   0.945   0.961   0.981   1.018
120   V        -1.811  -1.730  -1.681  -1.722  -1.627  -1.565  -1.636  -1.526  -1.420
121   K        -1.029  -1.071  -1.110  -1.125  -1.184  -1.227  -1.059  -1.103  -1.120
122   K        -0.108  -0.004  -0.278  -0.200  -0.037  -0.460  -0.193  -0.034  -0.468
123   H         0.917   0.936   0.963   1.194   1.213   1.240   0.961   0.981   1.018
124   D        -1.811  -1.800  -1.691  -1.757  -1.730  -1.590  -1.636  -1.589  -1.429
125   K         0.917   0.936   0.963   0.810   0.844   0.894   0.961   0.981   1.018
126   A        -1.243  -1.272  -1.131  -1.312  -1.361  -1.141  -1.347  -1.340  -1.146
127   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
128   L         0.917   0.936   0.963   0.972   0.988   1.040   0.961   0.981   1.018
129   L         0.917   0.936   0.963   0.972   0.988   1.040   0.961   0.981   1.018
130   S         0.917   0.936   0.963   0.953   0.984   1.023   0.961   0.981   1.018
131   M         0.917   0.936   0.963   1.153   1.174   1.203   0.961   0.981   1.018
132   A         0.917   0.936   0.963   0.996   1.020   1.062   0.961   0.981   1.018
133   N         0.917   0.936   0.963   1.039   1.075   1.100   0.961   0.981   1.018
134   A         0.917   0.936   0.963   0.996   1.020   1.062   0.961   0.981   1.018
135   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
136   P        -0.108  -0.275  -0.313   0.015  -0.259  -0.379  -0.193  -0.452  -0.527
137   N        -0.108  -0.275  -0.313   0.056  -0.184  -0.282  -0.193  -0.452  -0.527
138   T         0.917   0.936   0.963   0.910   0.933   0.985   0.961   0.981   1.018
139   N         0.917   0.936   0.963   1.039   1.075   1.100   0.961   0.981   1.018
140   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
141   S         0.917   0.936   0.963   0.953   0.984   1.023   0.961   0.981   1.018
142   Q         0.917   0.936   0.963   1.135   1.155   1.187   0.961   0.981   1.018
143   F         0.917   0.936   0.963   0.866   0.894   0.945   0.961   0.981   1.018
144   F         0.917   0.936   0.963   0.866   0.894   0.945   0.961   0.981   1.018
145   I         0.917   0.936   0.963   0.941   0.970   1.012   0.961   0.981   1.018
146   T         0.917   0.936   0.963   0.910   0.933   0.985   0.961   0.981   1.018
147   T         0.917   0.936   0.963   0.910   0.933   0.985   0.961   0.981   1.018
148   V         0.917   0.936   0.963   0.941   0.973   1.012   0.961   0.981   1.018
149   P        -0.108  -0.275  -0.313   0.046  -0.212  -0.316  -0.193  -0.452  -0.527
150   C        -0.108  -0.275  -0.313   0.213  -0.064  -0.191  -0.193  -0.452  -0.527
151   P        -0.108  -0.275  -0.313   0.049  -0.207  -0.311  -0.193  -0.452  -0.527
152   W         0.917   0.936   0.963   1.241   1.263   1.282   0.961   0.981   1.018
153   L         0.917   0.936   0.963   0.972   0.988   1.040   0.961   0.981   1.018
154   D         0.917   0.936   0.963   1.033   1.067   1.095   0.961   0.981   1.018
155   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
156   K        -0.108  -0.102  -0.293  -0.178  -0.155  -0.445  -0.193  -0.179  -0.493
157   H         0.917   0.936   0.963   1.194   1.213   1.240   0.961   0.981   1.018
158   V         0.917   0.936   0.963   0.941   0.973   1.012   0.961   0.981   1.018
159   V         0.917   0.936   0.963   0.941   0.973   1.012   0.961   0.981   1.018
160   F         0.917   0.936   0.963   0.866   0.894   0.945   0.961   0.981   1.018
161   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
162   E         0.917   0.936   0.963   0.922   0.965   0.996   0.961   0.981   1.018
163   V         0.917   0.936   0.963   0.941   0.973   1.012   0.961   0.981   1.018
164   T        -1.029  -1.147  -1.123  -1.024  -1.216  -1.170  -1.059  -1.191  -1.136
165   K        -1.243  -1.116  -1.122  -1.457  -1.207  -1.204  -1.347  -1.166  -1.136
166   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
167   M        -1.029  -1.071  -1.110  -0.733  -0.799  -0.889  -1.059  -1.103  -1.120
168   D        -0.108   0.008  -0.284   0.031   0.213  -0.271  -0.193  -0.016  -0.479
169   I        -1.029  -1.071  -1.110  -1.014  -1.086  -1.157  -1.059  -1.103  -1.120
170   V         0.917   0.936   0.963   0.941   0.973   1.012   0.961   0.981   1.018
171   K        -0.108  -0.275  -0.313  -0.197  -0.443  -0.516  -0.193  -0.452  -0.527
172   A        -1.243  -1.090  -1.123  -1.479  -1.247  -1.243  -1.347  -1.145  -1.137
173   I         0.917   0.936   0.963   0.941   0.970   1.012   0.961   0.981   1.018
174   E         0.917   0.936   0.963   0.922   0.965   0.996   0.961   0.981   1.018
175   S        -1.029  -1.147  -1.123  -0.945  -1.112  -1.082  -1.059  -1.191  -1.136
176   Y        -1.811  -1.800  -1.691  -1.609  -1.617  -1.464  -1.636  -1.589  -1.429
177   G        -0.108  -0.275  -0.313  -0.432  -0.700  -0.740  -0.193  -0.452  -0.527
178   T        -0.108  -0.102  -0.293  -0.090  -0.077  -0.385  -0.193  -0.179  -0.493
179   A        -1.811  -1.577  -1.669  -1.982  -1.659  -1.680  -1.636  -1.357  -1.409
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   S        -0.108  -0.275  -0.313  -0.009  -0.243  -0.313  -0.193  -0.452  -0.527
182   G        -0.108  -0.275  -0.313  -0.373  -0.606  -0.622  -0.193  -0.452  -0.527
183   K        -1.811  -1.577  -1.669  -1.678  -1.303  -1.454  -1.636  -1.357  -1.409
184   P         0.917   0.936   0.963   1.051   1.085   1.111   0.961   0.981   1.018
185   R        -1.029  -1.147  -1.123  -0.775  -0.963  -0.939  -1.059  -1.191  -1.136
186   A        -1.029  -1.147  -1.123  -0.954  -1.148  -1.131  -1.059  -1.191  -1.136
187   E        -1.811  -1.773  -1.686  -1.883  -1.772  -1.643  -1.636  -1.567  -1.424
188   I         0.917   0.936   0.963   0.941   0.970   1.012   0.961   0.981   1.018
189   V        -0.108  -0.275  -0.313  -0.094  -0.366  -0.467  -0.193  -0.452  -0.527
190   I        -0.108  -0.004  -0.278  -0.062   0.097  -0.339  -0.193  -0.034  -0.468
191   E        -0.108  -0.275  -0.313  -0.067  -0.306  -0.390  -0.193  -0.452  -0.527
192   E        -0.108  -0.275  -0.313  -0.113  -0.374  -0.482  -0.193  -0.452  -0.527
193   A        -1.243  -1.108  -1.121  -1.154  -0.960  -0.969  -1.347  -1.172  -1.136
194   G         0.917   0.936   0.963   0.603   0.629   0.709   0.961   0.981   1.018
195   E         0.917   0.936   0.963   0.922   0.965   0.996   0.961   0.981   1.018
196   L        -0.108  -0.004  -0.278  -0.032   0.115  -0.314  -0.193  -0.034  -0.468
197   -        -0.234  -0.320  -0.326  -0.390  -0.532  -0.537  -0.392  -0.525  -0.548
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
270   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
280   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -0.502  -0.456  -0.363  -0.688  -0.608  -0.450  -0.842  -0.755  -0.611
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25719
Output conservation file - output/P25719
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
