1     M         1.837   1.887   2.007   2.115   2.199   2.378   2.074   2.152   2.375
2     N        -0.165  -0.143  -0.047  -0.248  -0.204  -0.070  -0.469  -0.433  -0.307
3     A        -0.691  -0.739  -0.621  -0.721  -0.812  -0.645  -0.787  -0.838  -0.690
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     N         1.837   1.887   2.007   1.883   1.960   2.143   2.074   2.152   2.375
8     I         1.122   1.011   0.943   1.292   1.164   1.064   1.205   1.011   0.850
9     W         1.122   1.011   0.943   1.570   1.445   1.340   1.205   1.011   0.850
10    V        -0.012  -0.071   0.023  -0.091  -0.173  -0.037  -0.285  -0.341  -0.218
11    A         1.122   1.011   0.943   1.114   0.945   0.839   1.205   1.011   0.850
12    A         1.837   1.887   2.007   1.768   1.827   2.027   2.074   2.152   2.375
13    S         0.582   0.606   0.702   0.398   0.424   0.541   0.211   0.237   0.356
14    D         1.122   1.168   0.962   1.109   1.184   0.892   1.205   1.276   0.886
15    G         0.582   0.606   0.702   0.411   0.442   0.568   0.211   0.237   0.356
16    N        -1.327  -1.373  -1.352  -1.050  -1.117  -1.127  -1.031  -1.067  -1.004
17    L        -1.451  -1.397  -1.360  -1.411  -1.391  -1.271  -1.155  -1.102  -1.014
18    D        -0.793  -0.782  -0.921  -0.791  -0.794  -1.032  -0.658  -0.645  -0.772
19    R        -0.998  -1.057  -0.992  -0.792  -0.845  -0.751  -0.906  -0.955  -0.851
20    V         1.122   1.011   0.943   1.317   1.177   1.071   1.205   1.011   0.850
21    E        -0.200  -0.341  -0.440  -0.367  -0.602  -0.757  -0.161  -0.345  -0.466
22    H        -1.327  -1.298  -1.331  -1.045  -1.017  -1.048  -1.031  -0.996  -0.985
23    I        -0.998  -1.069  -0.986  -0.637  -0.747  -0.622  -0.906  -0.958  -0.843
24    L        -0.012  -0.075   0.020  -0.207  -0.277  -0.121  -0.285  -0.348  -0.224
25    R        -1.451  -1.371  -1.358  -1.667  -1.566  -1.504  -1.155  -1.078  -1.013
26    E        -1.451  -1.363  -1.357  -1.399  -1.249  -1.275  -1.155  -1.072  -1.012
27    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    A        -0.793  -0.778  -0.912  -0.662  -0.625  -0.916  -0.658  -0.640  -0.762
31    M        -1.779  -1.787  -1.680  -1.383  -1.383  -1.191  -1.279  -1.271  -1.133
32    T        -0.012  -0.083   0.017  -0.028  -0.136   0.012  -0.285  -0.362  -0.227
33    P         0.582   0.599   0.694   0.445   0.443   0.565   0.211   0.221   0.340
34    Q         0.441   0.345   0.168   0.655   0.536   0.282   0.460   0.313   0.031
35    S        -0.464  -0.559  -0.528  -0.427  -0.584  -0.564  -0.534  -0.642  -0.587
36    K         0.441   0.261   0.166   0.635   0.402   0.229   0.460   0.191   0.029
37    D         1.837   1.887   2.007   1.741   1.822   2.000   2.074   2.152   2.375
38    I        -0.012   0.072   0.038  -0.304  -0.200  -0.206  -0.285  -0.151  -0.193
39    N         1.122   1.011   0.943   1.277   1.150   1.060   1.205   1.011   0.850
40    G         1.837   1.887   2.007   1.900   1.978   2.160   2.074   2.152   2.375
41    Y         1.837   1.887   2.007   2.044   2.127   2.306   2.074   2.152   2.375
42    T         1.122   1.011   0.943   1.356   1.215   1.117   1.205   1.011   0.850
43    P         0.441   0.386   0.173   0.706   0.614   0.266   0.460   0.369   0.039
44    M         0.129   0.228   0.084   0.238   0.401   0.194  -0.037   0.121  -0.113
45    H         1.837   1.887   2.007   2.063   2.147   2.326   2.074   2.152   2.375
46    A         1.837   1.887   2.007   1.768   1.827   2.027   2.074   2.152   2.375
47    A         1.837   1.887   2.007   1.768   1.827   2.027   2.074   2.152   2.375
48    A         1.122   1.079   0.963   1.145   1.085   0.941   1.205   1.128   0.889
49    A         0.582   0.648   0.720   0.398   0.517   0.586   0.211   0.322   0.394
50    Y         1.837   1.887   2.007   2.044   2.127   2.306   2.074   2.152   2.375
51    G         1.122   1.011   0.943   1.268   1.129   1.018   1.205   1.011   0.850
52    H         1.837   1.887   2.007   2.063   2.147   2.326   2.074   2.152   2.375
53    L        -0.464  -0.453  -0.492  -0.467  -0.443  -0.464  -0.534  -0.504  -0.544
54    D         0.441   0.598   0.202   0.489   0.705   0.152   0.460   0.689   0.085
55    L         1.837   1.887   2.007   1.731   1.795   1.989   2.074   2.152   2.375
56    L         1.837   1.887   2.007   1.731   1.795   1.989   2.074   2.152   2.375
57    K        -0.012   0.049   0.029  -0.026   0.064   0.065  -0.285  -0.215  -0.213
58    K        -0.998  -1.044  -0.998  -0.829  -0.874  -0.821  -0.906  -0.939  -0.857
59    M         1.122   1.175   0.966   1.133   1.201   0.964   1.205   1.286   0.896
60    C        -0.216  -0.151  -0.058  -0.216  -0.121   0.032  -0.534  -0.443  -0.322
61    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    E         0.441   0.570   0.213   0.275   0.450  -0.062   0.460   0.649   0.102
63    Y        -1.122  -1.145  -1.025  -0.831  -0.824  -0.654  -1.031  -1.034  -0.883
64    N         0.129   0.043   0.046   0.166   0.054   0.023  -0.037  -0.149  -0.171
65    G         1.122   1.011   0.943   1.277   1.142   1.038   1.205   1.011   0.850
66    D         1.122   1.011   0.943   1.127   1.000   0.903   1.205   1.011   0.850
67    I         0.770   0.724   0.735   0.781   0.700   0.678   0.584   0.475   0.427
68    N         1.122   1.011   0.943   1.231   1.084   0.957   1.205   1.011   0.850
69    V        -0.012  -0.089   0.016  -0.083  -0.203  -0.048  -0.285  -0.372  -0.231
70    L        -1.122  -1.082  -1.015  -1.003  -0.940  -0.843  -1.031  -0.981  -0.874
71    D         1.837   1.887   2.007   1.741   1.822   2.000   2.074   2.152   2.375
72    N        -0.669  -0.699  -0.589  -0.823  -0.889  -0.716  -0.782  -0.803  -0.661
73    D         0.770   0.885   0.825   0.493   0.695   0.519   0.584   0.784   0.615
74    G         1.122   1.168   0.962   1.268   1.341   1.049   1.205   1.276   0.886
75    D         0.770   0.685   0.743   0.493   0.300   0.331   0.584   0.396   0.444
76    T         1.122   1.240   0.970   1.331   1.483   1.108   1.205   1.389   0.903
77    P         0.770   0.734   0.757   0.820   0.733   0.718   0.584   0.495   0.472
78    L         1.837   1.887   2.007   1.731   1.795   1.989   2.074   2.152   2.375
79    H         0.770   0.685   0.743   0.983   0.846   0.915   0.584   0.396   0.444
80    H         0.129   0.082   0.039   0.358   0.252   0.204  -0.037  -0.140  -0.186
81    V         0.582   0.618   0.707   0.612   0.665   0.803   0.211   0.261   0.367
82    E         1.837   1.887   2.007   1.555   1.625   1.812   2.074   2.152   2.375
83    D        -0.200  -0.341  -0.440  -0.167  -0.358  -0.559  -0.161  -0.345  -0.466
84    V        -0.545  -0.476  -0.522  -0.655  -0.574  -0.602  -0.658  -0.581  -0.587
85    A        -1.122  -1.056  -1.016  -1.316  -1.264  -1.134  -1.031  -0.963  -0.875
86    T        -0.464  -0.559  -0.513  -0.316  -0.466  -0.404  -0.534  -0.625  -0.568
87    A         1.837   1.887   2.007   1.768   1.827   2.027   2.074   2.152   2.375
88    R        -0.464  -0.427  -0.515  -0.292  -0.220  -0.328  -0.534  -0.486  -0.570
89    L        -1.327  -1.386  -1.339  -1.201  -1.297  -1.197  -1.031  -1.077  -0.992
90    I        -0.012   0.106   0.037  -0.179  -0.029  -0.058  -0.285  -0.122  -0.197
91    V         0.129   0.002   0.035   0.196  -0.012   0.012  -0.037  -0.217  -0.191
92    E         1.122   1.079   0.963   0.922   0.872   0.710   1.205   1.128   0.889
93    E         0.129   0.167   0.061  -0.124  -0.077  -0.203  -0.037  -0.001  -0.152
94    L         0.441   0.422   0.195   0.543   0.518   0.254   0.460   0.430   0.074
95    G        -0.012  -0.049   0.017  -0.099  -0.139  -0.040  -0.285  -0.327  -0.228
96    G         0.129   0.084   0.066   0.017  -0.062  -0.101  -0.037  -0.083  -0.136
97    D         1.122   1.220   0.969   1.119   1.258   0.926   1.205   1.358   0.900
98    F        -1.122  -1.053  -1.015  -0.727  -0.649  -0.542  -1.031  -0.956  -0.876
99    T        -0.012   0.050   0.032  -0.098   0.015  -0.045  -0.285  -0.187  -0.200
100   I        -0.464  -0.446  -0.494  -0.470  -0.419  -0.523  -0.534  -0.494  -0.542
101   R        -0.793  -0.800  -0.934  -0.531  -0.542  -0.747  -0.658  -0.665  -0.785
102   N         1.837   1.887   2.007   1.883   1.960   2.143   2.074   2.152   2.375
103   V        -0.464  -0.441  -0.507  -0.444  -0.423  -0.518  -0.534  -0.509  -0.565
104   E         0.582   0.615   0.706   0.023   0.066   0.191   0.211   0.254   0.365
105   G         1.837   1.887   2.007   1.900   1.978   2.160   2.074   2.152   2.375
106   Q        -0.136  -0.085  -0.036  -0.238  -0.148  -0.127  -0.410  -0.337  -0.288
107   T         0.770   0.798   0.768   0.838   0.874   0.786   0.584   0.619   0.497
108   P        -0.012   0.040   0.038  -0.071  -0.011   0.058  -0.285  -0.206  -0.197
109   Y        -1.451  -1.424  -1.358  -1.183  -1.144  -1.032  -1.155  -1.122  -1.013
110   D        -0.012   0.015   0.024  -0.267  -0.240  -0.233  -0.285  -0.254  -0.218
111   S        -0.669  -0.636  -0.582  -0.586  -0.539  -0.448  -0.782  -0.739  -0.651
112   F        -0.464  -0.378  -0.494  -0.254  -0.119  -0.269  -0.534  -0.411  -0.542
113   V         0.129   0.183   0.069  -0.113  -0.034  -0.173  -0.037   0.044  -0.138
114   E         0.770   0.685   0.743   0.379   0.202   0.277   0.584   0.396   0.444
115   N        -0.669  -0.618  -0.581  -1.048  -0.967  -0.883  -0.782  -0.715  -0.652
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   G        -0.464  -0.502  -0.517  -0.637  -0.733  -0.760  -0.534  -0.586  -0.577
118   E         0.770   0.724   0.735   0.370   0.272   0.246   0.584   0.475   0.427
119   D        -0.200  -0.284  -0.443   0.242   0.133  -0.148  -0.161  -0.271  -0.470
120   G         0.441   0.489   0.190   0.727   0.799   0.339   0.460   0.532   0.066
121   E         1.122   1.168   0.962   0.901   0.966   0.661   1.205   1.276   0.886
122   L         0.770   0.747   0.751   0.612   0.557   0.551   0.584   0.521   0.460
123   I        -0.012   0.044   0.025  -0.230  -0.156  -0.171  -0.285  -0.199  -0.213
124   E        -1.122  -1.118  -1.014  -1.100  -1.126  -0.943  -1.031  -1.009  -0.875
125   Y         1.837   1.887   2.007   2.044   2.127   2.306   2.074   2.152   2.375
126   M         0.129   0.214   0.075   0.074   0.189   0.000  -0.037   0.099  -0.122
127   R        -1.327  -1.386  -1.339  -1.073  -1.158  -1.138  -1.031  -1.077  -0.992
128   I        -1.451  -1.371  -1.358  -1.316  -1.202  -1.181  -1.155  -1.078  -1.013
129   K        -0.464  -0.459  -0.513  -0.477  -0.449  -0.496  -0.534  -0.508  -0.565
130   S        -1.327  -1.386  -1.339  -1.168  -1.312  -1.250  -1.031  -1.077  -0.992
131   G         0.129   0.153   0.086   0.207   0.258   0.133  -0.037   0.020  -0.103
132   V        -1.103  -1.032  -1.012  -1.444  -1.361  -1.299  -1.008  -0.928  -0.869
133   A        -1.479  -1.377  -1.362  -1.334  -1.200  -1.148  -1.170  -1.065  -1.012
134   D        -1.479  -1.482  -1.400  -1.352  -1.365  -1.273  -1.170  -1.162  -1.044
135   V        -1.103  -1.050  -1.010  -0.936  -0.845  -0.759  -1.008  -0.945  -0.868
136   H        -0.962  -0.841  -0.963  -0.809  -0.603  -0.863  -0.846  -0.702  -0.816
137   G        -0.962  -0.848  -0.943  -0.709  -0.524  -0.697  -0.846  -0.710  -0.795
138   V        -0.586  -0.558  -0.557  -0.561  -0.521  -0.544  -0.683  -0.658  -0.622
139   D        -1.103  -1.026  -1.019  -1.411  -1.304  -1.303  -1.008  -0.923  -0.876
140   G        -0.520  -0.583  -0.563  -0.476  -0.567  -0.586  -0.575  -0.653  -0.622
141   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   I        -0.998  -1.051  -0.999  -0.881  -0.955  -0.885  -0.906  -0.944  -0.857
148   D        -0.793  -0.843  -0.931  -0.789  -0.883  -1.046  -0.658  -0.714  -0.782
149   S        -1.451  -1.357  -1.360  -1.282  -1.106  -1.120  -1.155  -1.062  -1.014
150   K        -0.669  -0.675  -0.578  -1.008  -0.982  -0.900  -0.782  -0.766  -0.648
151   L        -1.451  -1.357  -1.364  -1.417  -1.298  -1.301  -1.155  -1.061  -1.017
152   L        -0.200  -0.175  -0.405  -0.067  -0.040  -0.324  -0.161  -0.126  -0.421
153   E        -0.728  -0.748  -0.604  -1.058  -1.055  -0.858  -0.846  -0.850  -0.677
154   E        -1.103  -1.153  -1.038  -1.003  -1.050  -0.917  -1.008  -1.038  -0.893
155   F        -0.068  -0.127  -0.020  -0.172  -0.283  -0.108  -0.359  -0.419  -0.274
156   K         0.541   0.603   0.705   0.432   0.546   0.679   0.128   0.231   0.362
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   D        -0.998  -1.061  -1.004  -1.030  -1.164  -1.064  -0.906  -0.950  -0.861
165   N        -0.998  -0.953  -0.982  -0.814  -0.728  -0.783  -0.906  -0.854  -0.841
166   V        -0.012  -0.020   0.023  -0.075  -0.074  -0.019  -0.285  -0.276  -0.217
167   R         0.129   0.010   0.045   0.270   0.109   0.129  -0.037  -0.203  -0.174
168   Y         0.441   0.261   0.166   0.767   0.518   0.335   0.460   0.191   0.029
169   T        -0.464  -0.572  -0.519  -0.239  -0.374  -0.296  -0.534  -0.643  -0.575
170   L        -0.464  -0.439  -0.513  -0.397  -0.398  -0.396  -0.534  -0.530  -0.572
171   E         1.122   1.011   0.943   0.959   0.831   0.759   1.205   1.011   0.850
172   N         0.770   0.808   0.773   0.769   0.831   0.744   0.584   0.638   0.506
173   D         0.770   0.816   0.783   0.370   0.436   0.338   0.584   0.654   0.528
174   P        -0.012  -0.025   0.013  -0.087  -0.098   0.006  -0.285  -0.285  -0.229
175   E        -0.998  -0.929  -0.965  -1.207  -1.154  -1.159  -0.906  -0.840  -0.827
176   E        -1.327  -1.301  -1.331  -1.381  -1.354  -1.348  -1.031  -0.999  -0.985
177   G        -0.793  -0.764  -0.906  -1.002  -0.979  -1.215  -0.658  -0.625  -0.756
178   A        -0.669  -0.603  -0.576  -0.850  -0.770  -0.728  -0.782  -0.709  -0.644
179   D         0.129   0.043   0.046  -0.111  -0.264  -0.302  -0.037  -0.166  -0.175
180   E        -0.464  -0.422  -0.495  -0.405  -0.319  -0.475  -0.534  -0.472  -0.548
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   A        -0.520  -0.554  -0.537  -0.864  -0.934  -0.933  -0.575  -0.618  -0.589
187   T        -0.586  -0.481  -0.532  -0.699  -0.533  -0.614  -0.683  -0.545  -0.588
188   L        -1.103  -1.124  -1.032  -1.332  -1.320  -1.162  -1.008  -1.016  -0.887
189   Q         0.441   0.407   0.190   0.318   0.279  -0.017   0.460   0.409   0.065
190   R        -0.200  -0.341  -0.440   0.146  -0.047  -0.213  -0.161  -0.345  -0.466
191   R         0.770   0.773   0.776   0.843   0.849   0.805   0.584   0.572   0.513
192   R         0.129   0.028   0.036   0.177   0.025   0.014  -0.037  -0.192  -0.192
193   Q        -0.669  -0.698  -0.589  -0.706  -0.745  -0.600  -0.782  -0.802  -0.661
194   L         0.582   0.648   0.720   0.337   0.454   0.524   0.211   0.322   0.394
195   E         0.441   0.448   0.197   0.290   0.295  -0.058   0.460   0.467   0.076
196   Q        -1.779  -1.702  -1.673  -1.831  -1.712  -1.646  -1.279  -1.205  -1.128
197   I         1.122   1.011   0.943   1.253   1.106   0.977   1.205   1.011   0.850
198   I        -0.998  -0.989  -0.988  -0.978  -0.999  -0.922  -0.906  -0.891  -0.847
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   T        -1.779  -1.719  -1.667  -1.465  -1.359  -1.300  -1.279  -1.220  -1.124
204   G        -0.012  -0.063   0.010  -0.040  -0.078   0.028  -0.285  -0.327  -0.233
205   D        -0.012  -0.028   0.027  -0.473  -0.480  -0.383  -0.285  -0.289  -0.214
206   N         1.122   1.011   0.943   1.231   1.084   0.957   1.205   1.011   0.850
207   A        -0.464  -0.594  -0.531  -0.286  -0.463  -0.375  -0.534  -0.673  -0.589
208   E         1.122   1.079   0.963   0.901   0.846   0.663   1.205   1.128   0.889
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   E        -0.464  -0.475  -0.513  -0.785  -0.844  -0.849  -0.534  -0.559  -0.570
215   E        -0.012   0.030   0.012  -0.465  -0.427  -0.398  -0.285  -0.236  -0.233
216   L         1.837   1.887   2.007   1.731   1.795   1.989   2.074   2.152   2.375
217   E        -0.012   0.056   0.025  -0.207  -0.078  -0.113  -0.285  -0.188  -0.211
218   R        -1.451  -1.429  -1.372  -1.502  -1.415  -1.375  -1.155  -1.124  -1.022
219   Y        -0.545  -0.552  -0.545  -0.499  -0.517  -0.453  -0.658  -0.653  -0.611
220   I        -0.216  -0.200  -0.083  -0.420  -0.407  -0.240  -0.534  -0.511  -0.358
221   R        -0.464  -0.555  -0.520  -0.360  -0.501  -0.477  -0.534  -0.620  -0.572
222   A        -1.451  -1.389  -1.355  -1.553  -1.451  -1.426  -1.155  -1.092  -1.010
223   M         0.129   0.214   0.075   0.102   0.214   0.021  -0.037   0.099  -0.122
224   V        -0.012  -0.053   0.015  -0.083  -0.152  -0.050  -0.285  -0.334  -0.232
225   R        -1.451  -1.471  -1.370  -1.138  -1.187  -1.019  -1.155  -1.157  -1.021
226   E        -0.352  -0.371  -0.490  -0.496  -0.530  -0.689  -0.359  -0.388  -0.529
227   Q         0.024  -0.013   0.020   0.105   0.083   0.112  -0.197  -0.233  -0.205
228   M         0.024  -0.011   0.003   0.297   0.241   0.264  -0.197  -0.262  -0.239
229   L        -1.479  -1.486  -1.400  -1.335  -1.400  -1.234  -1.170  -1.164  -1.044
230   G        -1.562  -1.546  -1.415  -1.599  -1.590  -1.378  -1.237  -1.210  -1.056
231   Q        -0.686  -0.699  -0.614  -0.547  -0.557  -0.432  -0.796  -0.800  -0.684
232   G        -1.124  -1.071  -1.027  -1.124  -1.032  -0.992  -1.017  -0.952  -0.880
233   S        -0.686  -0.694  -0.587  -0.805  -0.835  -0.677  -0.796  -0.795  -0.656
234   M        -0.082  -0.057  -0.035  -0.517  -0.479  -0.402  -0.354  -0.315  -0.291
235   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   E        -1.124  -1.114  -1.050  -1.011  -0.990  -0.932  -1.017  -0.999  -0.903
245   P        -0.686  -0.714  -0.612  -0.888  -0.916  -0.759  -0.796  -0.816  -0.682
246   D        -1.124  -1.114  -1.050  -1.039  -1.029  -0.940  -1.017  -0.999  -0.903
247   S        -0.998  -1.078  -1.002  -0.838  -0.926  -0.823  -0.906  -0.968  -0.859
248   K        -0.136  -0.149  -0.062  -0.155  -0.171  -0.048  -0.410  -0.439  -0.327
249   R         1.837   1.887   2.007   1.989   2.068   2.250   2.074   2.152   2.375
250   R        -0.998  -1.078  -1.002  -0.790  -0.871  -0.763  -0.906  -0.968  -0.859
251   K        -0.545  -0.522  -0.537  -0.838  -0.809  -0.826  -0.658  -0.625  -0.602
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25631
Output conservation file - output/P25631
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
