1     M         1.023   1.073   1.132   1.174   1.237   1.323   1.098   1.161   1.248
2     S         1.023   1.073   1.132   0.947   1.017   1.122   1.098   1.161   1.248
3     R         1.023   1.073   1.132   0.993   1.059   1.162   1.098   1.161   1.248
4     P         1.023   1.073   1.132   1.143   1.212   1.295   1.098   1.161   1.248
5     E         1.023   1.073   1.132   1.035   1.108   1.199   1.098   1.161   1.248
6     E        -1.201  -1.277  -1.172  -1.144  -1.231  -1.061  -1.249  -1.301  -1.122
7     L        -0.627  -0.783  -0.688  -0.788  -1.011  -0.833  -0.802  -0.995  -0.846
8     A         0.332   0.226   0.085   0.323   0.179  -0.076   0.315   0.145  -0.125
9     P         0.332   0.226   0.085   0.516   0.372   0.107   0.315   0.145  -0.125
10    P         0.332   0.226   0.085   0.516   0.372   0.107   0.315   0.145  -0.125
11    E         0.332   0.226   0.085   0.413   0.276   0.031   0.315   0.145  -0.125
12    I        -0.248  -0.187  -0.040  -0.477  -0.393  -0.143  -0.690  -0.587  -0.357
13    F         0.332   0.226   0.085   0.538   0.422   0.204   0.315   0.145  -0.125
14    Y         1.023   1.073   1.132   1.203   1.266   1.349   1.098   1.161   1.248
15    N         0.332   0.226   0.085   0.530   0.394   0.129   0.315   0.145  -0.125
16    D         1.023   1.073   1.132   1.000   1.069   1.169   1.098   1.161   1.248
17    S        -1.201  -1.309  -1.180  -1.242  -1.393  -1.176  -1.249  -1.334  -1.129
18    E         1.023   1.073   1.132   1.035   1.108   1.199   1.098   1.161   1.248
19    A        -0.248  -0.153  -0.027  -0.652  -0.477  -0.270  -0.690  -0.522  -0.333
20    H        -2.154  -2.118  -1.892  -2.139  -2.128  -1.741  -1.808  -1.714  -1.423
21    K         1.023   1.073   1.132   0.889   0.966   1.070   1.098   1.161   1.248
22    Y         1.023   1.073   1.132   1.203   1.266   1.349   1.098   1.161   1.248
23    T        -0.008  -0.044  -0.017  -0.038  -0.136  -0.138  -0.243  -0.318  -0.313
24    G        -1.399  -1.148  -1.169  -1.602  -1.165  -1.237  -1.473  -1.154  -1.117
25    S         0.332   0.146   0.077   0.348   0.107   0.004   0.315   0.013  -0.139
26    T        -0.008  -0.037  -0.013  -0.038  -0.122  -0.128  -0.243  -0.305  -0.305
27    R         1.023   1.073   1.132   0.993   1.059   1.162   1.098   1.161   1.248
28    V        -0.008  -0.138  -0.031  -0.019  -0.285  -0.120  -0.243  -0.493  -0.338
29    Q         1.023   1.073   1.132   1.118   1.177   1.274   1.098   1.161   1.248
30    H        -0.945  -1.178  -1.162  -0.531  -0.912  -0.939  -0.914  -1.172  -1.108
31    I         1.023   1.073   1.132   1.055   1.110   1.217   1.098   1.161   1.248
32    Q         1.023   1.073   1.132   1.118   1.177   1.274   1.098   1.161   1.248
33    A         0.332   0.146   0.077   0.357   0.107  -0.000   0.315   0.013  -0.139
34    K        -0.326  -0.619  -0.644  -0.350  -0.770  -0.834  -0.355  -0.748  -0.783
35    M         1.023   1.073   1.132   1.174   1.237   1.323   1.098   1.161   1.248
36    T         0.332   0.146   0.077   0.479   0.197   0.059   0.315   0.013  -0.139
37    L        -0.326  -0.619  -0.644  -0.358  -0.765  -0.827  -0.355  -0.748  -0.783
38    R         1.023   1.073   1.132   0.993   1.059   1.162   1.098   1.161   1.248
39    A        -0.326  -0.154  -0.589  -0.264  -0.031  -0.655  -0.355  -0.115  -0.707
40    L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
41    E         1.023   1.073   1.132   1.035   1.108   1.199   1.098   1.161   1.248
42    L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
43    L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
44    N        -0.008  -0.138  -0.031   0.020  -0.247  -0.109  -0.243  -0.493  -0.338
45    L        -0.945  -0.975  -1.132  -0.943  -1.004  -1.207  -0.914  -0.947  -1.076
46    Q        -1.717  -1.602  -1.547  -1.671  -1.520  -1.435  -1.585  -1.427  -1.286
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    P        -2.154  -2.062  -1.882  -2.020  -1.960  -1.622  -1.808  -1.673  -1.417
50    C        -1.519  -1.179  -1.510  -1.185  -0.728  -1.202  -1.361  -0.961  -1.251
51    S        -0.326  -0.126  -0.591  -0.222   0.034  -0.549  -0.355  -0.076  -0.710
52    F        -0.008   0.116   0.016   0.054   0.249   0.062  -0.243  -0.037  -0.251
53    I         0.332   0.490   0.107   0.415   0.612   0.046   0.315   0.544  -0.085
54    L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
55    D         1.023   1.073   1.132   1.000   1.069   1.169   1.098   1.161   1.248
56    I        -0.326  -0.214  -0.597  -0.187  -0.039  -0.627  -0.355  -0.192  -0.718
57    G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
58    C         1.023   1.073   1.132   1.284   1.347   1.421   1.098   1.161   1.248
59    G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
60    S         1.023   1.073   1.132   0.947   1.017   1.122   1.098   1.161   1.248
61    G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
62    L         0.332   0.146   0.077   0.260   0.020  -0.095   0.315   0.013  -0.139
63    S         1.023   1.073   1.132   0.947   1.017   1.122   1.098   1.161   1.248
64    G         0.332   0.146   0.077   0.281   0.025  -0.063   0.315   0.013  -0.139
65    E         0.332   0.146   0.077   0.430   0.183   0.063   0.315   0.013  -0.139
66    I         0.332   0.396   0.099   0.446   0.522   0.107   0.315   0.408  -0.100
67    L        -0.326  -0.390  -0.616  -0.373  -0.487  -0.814  -0.355  -0.458  -0.744
68    T        -0.326  -0.619  -0.644  -0.131  -0.581  -0.667  -0.355  -0.748  -0.783
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    Q        -0.945  -1.092  -1.151  -0.792  -1.056  -1.138  -0.914  -1.086  -1.096
74    E         0.332   0.146   0.077   0.430   0.183   0.063   0.315   0.013  -0.139
75    G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    H        -0.008   0.138   0.037   0.200   0.417   0.216  -0.243   0.001  -0.213
79    V        -1.201  -0.985  -1.143  -1.039  -0.724  -0.931  -1.249  -0.959  -1.088
80    W         0.332   0.146   0.077   0.688   0.426   0.268   0.315   0.013  -0.139
81    C        -0.763  -0.533  -0.650  -0.714  -0.391  -0.537  -1.026  -0.686  -0.794
82    G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
83    L        -0.190  -0.014   0.010  -0.375  -0.029  -0.060  -0.579  -0.264  -0.263
84    D         1.023   1.073   1.132   1.000   1.069   1.169   1.098   1.161   1.248
85    I         1.023   1.073   1.132   1.055   1.110   1.217   1.098   1.161   1.248
86    S         0.332   0.396   0.099   0.320   0.412  -0.030   0.315   0.408  -0.100
87    P         1.023   1.073   1.132   1.143   1.212   1.295   1.098   1.161   1.248
88    S         0.332   0.434   0.104   0.348   0.485   0.047   0.315   0.464  -0.091
89    M         1.023   1.073   1.132   1.174   1.237   1.323   1.098   1.161   1.248
90    L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
91    A        -0.326  -0.619  -0.644  -0.283  -0.720  -0.792  -0.355  -0.748  -0.783
92    T        -0.326  -0.390  -0.616  -0.107  -0.226  -0.560  -0.355  -0.458  -0.744
93    G        -0.248  -0.150  -0.026  -0.697  -0.509  -0.302  -0.690  -0.515  -0.331
94    L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
95    S        -1.717  -1.617  -1.557  -1.704  -1.571  -1.449  -1.585  -1.459  -1.295
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    R        -0.326  -0.476  -0.625  -0.242  -0.455  -0.709  -0.355  -0.562  -0.756
98    E        -0.627  -0.564  -0.664  -0.698  -0.613  -0.800  -0.802  -0.713  -0.815
99    L        -0.763  -0.811  -0.677  -0.962  -0.971  -0.788  -1.026  -1.022  -0.832
100   E         1.023   1.073   1.132   1.035   1.108   1.199   1.098   1.161   1.248
101   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
102   D         1.023   1.073   1.132   1.000   1.069   1.169   1.098   1.161   1.248
103   L         0.332   0.434   0.104   0.266   0.418  -0.036   0.315   0.464  -0.091
104   M        -0.763  -0.796  -0.677  -0.794  -0.822  -0.678  -1.026  -1.000  -0.830
105   L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
106   Q        -2.154  -2.019  -1.882  -2.000  -1.787  -1.594  -1.808  -1.643  -1.417
107   D         1.023   1.073   1.132   1.000   1.069   1.169   1.098   1.161   1.248
108   M        -1.201  -1.052  -1.154  -1.090  -0.896  -1.067  -1.249  -1.064  -1.102
109   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
110   T        -1.399  -1.317  -1.186  -1.370  -1.258  -1.061  -1.473  -1.343  -1.135
111   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
112   I        -0.248  -0.137  -0.022  -0.477  -0.284  -0.103  -0.690  -0.492  -0.322
113   P         1.023   1.073   1.132   1.143   1.212   1.295   1.098   1.161   1.248
114   F         1.023   1.073   1.132   1.121   1.198   1.276   1.098   1.161   1.248
115   R         1.023   1.073   1.132   0.993   1.059   1.162   1.098   1.161   1.248
116   A        -0.008  -0.042  -0.016  -0.116  -0.175  -0.141  -0.243  -0.315  -0.312
117   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
118   S        -0.627  -0.506  -0.657  -0.609  -0.468  -0.685  -0.802  -0.643  -0.804
119   F         1.023   1.073   1.132   1.121   1.198   1.276   1.098   1.161   1.248
120   D         1.023   1.073   1.132   1.000   1.069   1.169   1.098   1.161   1.248
121   A         0.332   0.146   0.077   0.325   0.052  -0.086   0.315   0.013  -0.139
122   A         0.332   0.146   0.077   0.354   0.106  -0.006   0.315   0.013  -0.139
123   I         1.023   1.073   1.132   1.055   1.110   1.217   1.098   1.161   1.248
124   S         1.023   1.073   1.132   0.947   1.017   1.122   1.098   1.161   1.248
125   I         1.023   1.073   1.132   1.055   1.110   1.217   1.098   1.161   1.248
126   S         1.023   1.073   1.132   0.947   1.017   1.122   1.098   1.161   1.248
127   A        -0.008   0.176   0.034  -0.133   0.151  -0.080  -0.243   0.065  -0.218
128   I         1.023   1.073   1.132   1.055   1.110   1.217   1.098   1.161   1.248
129   Q         1.023   1.073   1.132   1.118   1.177   1.274   1.098   1.161   1.248
130   W         1.023   1.073   1.132   1.298   1.362   1.433   1.098   1.161   1.248
131   L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
132   C         0.332   0.146   0.077   0.644   0.364   0.178   0.315   0.013  -0.139
133   N         1.023   1.073   1.132   1.152   1.227   1.304   1.098   1.161   1.248
134   A         1.023   1.073   1.132   0.962   1.034   1.135   1.098   1.161   1.248
135   D         0.332   0.226   0.085   0.383   0.246   0.016   0.315   0.145  -0.125
136   T        -0.945  -0.952  -1.135  -0.725  -0.796  -1.069  -0.914  -0.920  -1.079
137   S        -0.627  -0.731  -0.672  -0.753  -0.886  -0.810  -0.802  -0.904  -0.823
138   Y        -1.717  -1.780  -1.574  -1.546  -1.614  -1.338  -1.585  -1.583  -1.308
139   N        -0.763  -0.785  -0.685  -0.849  -0.834  -0.700  -1.026  -0.998  -0.843
140   D        -0.945  -1.178  -1.162  -0.798  -1.149  -1.123  -0.914  -1.172  -1.108
141   P         1.023   1.073   1.132   1.143   1.212   1.295   1.098   1.161   1.248
142   K        -0.326  -0.619  -0.644  -0.336  -0.747  -0.799  -0.355  -0.748  -0.783
143   Q        -1.717  -1.615  -1.554  -1.750  -1.583  -1.459  -1.585  -1.436  -1.292
144   R         1.023   1.073   1.132   0.993   1.059   1.162   1.098   1.161   1.248
145   L         0.332   0.434   0.104   0.278   0.428  -0.006   0.315   0.464  -0.091
146   M        -1.201  -1.338  -1.181  -1.139  -1.322  -1.149  -1.249  -1.346  -1.129
147   R        -0.326  -0.162  -0.591  -0.236  -0.019  -0.638  -0.355  -0.125  -0.710
148   F         1.023   1.073   1.132   1.121   1.198   1.276   1.098   1.161   1.248
149   F         1.023   1.073   1.132   1.121   1.198   1.276   1.098   1.161   1.248
150   N        -0.326  -0.476  -0.625  -0.074  -0.284  -0.566  -0.355  -0.562  -0.756
151   T        -0.627  -0.561  -0.659  -0.658  -0.591  -0.772  -0.802  -0.708  -0.808
152   L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
153   Y        -0.008   0.182   0.046   0.106   0.396   0.144  -0.243   0.074  -0.195
154   A         0.332   0.146   0.077   0.349   0.093  -0.021   0.315   0.013  -0.139
155   A        -0.008   0.194   0.050  -0.190   0.131  -0.120  -0.243   0.093  -0.188
156   L         0.332   0.146   0.077   0.278   0.054  -0.047   0.315   0.013  -0.139
157   K        -0.008   0.081   0.010  -0.237  -0.090  -0.228  -0.243  -0.096  -0.262
158   K        -0.190  -0.014   0.010  -0.531  -0.198  -0.197  -0.579  -0.264  -0.263
159   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
160   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
161   K        -0.008  -0.138  -0.031  -0.237  -0.482  -0.303  -0.243  -0.493  -0.338
162   F        -0.190  -0.188  -0.039  -0.378  -0.421  -0.186  -0.579  -0.588  -0.355
163   V         1.023   1.073   1.132   1.094   1.158   1.252   1.098   1.161   1.248
164   A        -0.627  -0.810  -0.689  -0.602  -0.830  -0.626  -0.802  -1.021  -0.846
165   Q         1.023   1.073   1.132   1.118   1.177   1.274   1.098   1.161   1.248
166   F         0.332   0.146   0.077   0.528   0.294   0.165   0.315   0.013  -0.139
167   Y         1.023   1.073   1.132   1.203   1.266   1.349   1.098   1.161   1.248
168   P         1.023   1.073   1.132   1.143   1.212   1.295   1.098   1.161   1.248
169   K        -0.945  -1.026  -1.140  -0.915  -1.037  -1.182  -0.914  -1.000  -1.084
170   N         0.332   0.146   0.077   0.546   0.296   0.155   0.315   0.013  -0.139
171   D         0.332   0.146   0.077   0.383   0.127   0.002   0.315   0.013  -0.139
172   D        -1.717  -1.731  -1.568  -1.722  -1.760  -1.501  -1.585  -1.546  -1.304
173   Q         0.332   0.146   0.077   0.489   0.210   0.067   0.315   0.013  -0.139
174   V        -2.154  -2.123  -1.892  -2.034  -2.017  -1.677  -1.808  -1.717  -1.424
175   D        -0.883  -0.858  -0.715  -1.050  -1.009  -0.786  -1.137  -1.091  -0.879
176   D        -1.717  -1.518  -1.556  -1.553  -1.283  -1.335  -1.585  -1.371  -1.294
177   I         1.023   1.073   1.132   1.055   1.110   1.217   1.098   1.161   1.248
178   L        -1.201  -1.278  -1.175  -1.252  -1.325  -1.133  -1.249  -1.302  -1.124
179   Q        -1.399  -1.387  -1.193  -1.566  -1.549  -1.266  -1.473  -1.404  -1.142
180   S        -0.326  -0.373  -0.614  -0.264  -0.342  -0.696  -0.355  -0.439  -0.741
181   A         1.023   1.073   1.132   0.962   1.034   1.135   1.098   1.161   1.248
182   K        -0.326  -0.619  -0.644  -0.333  -0.746  -0.790  -0.355  -0.748  -0.783
183   V        -1.201  -1.179  -1.177  -1.266  -1.314  -1.310  -1.249  -1.217  -1.126
184   A         0.332   0.396   0.099   0.357   0.447   0.036   0.315   0.408  -0.100
185   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
186   F         1.023   1.073   1.132   1.121   1.198   1.276   1.098   1.161   1.248
187   S        -0.763  -0.796  -0.677  -1.112  -1.123  -0.928  -1.026  -1.000  -0.830
188   G         0.332   0.226   0.085   0.259   0.111  -0.107   0.315   0.145  -0.125
189   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
190   L        -0.008  -0.080  -0.022  -0.232  -0.355  -0.263  -0.243  -0.385  -0.321
191   V        -0.326  -0.371  -0.610  -0.154  -0.233  -0.634  -0.355  -0.413  -0.736
192   V        -0.763  -0.813  -0.683  -0.865  -0.926  -0.713  -1.026  -1.042  -0.841
193   D         1.023   1.073   1.132   1.000   1.069   1.169   1.098   1.161   1.248
194   D        -0.326  -0.442  -0.620  -0.184  -0.329  -0.581  -0.355  -0.521  -0.750
195   P         1.023   1.073   1.132   1.143   1.212   1.295   1.098   1.161   1.248
196   E         0.332   0.226   0.085   0.435   0.310   0.088   0.315   0.145  -0.125
197   S         0.332   0.226   0.085   0.342   0.207  -0.000   0.315   0.145  -0.125
198   K         1.023   1.073   1.132   0.889   0.966   1.070   1.098   1.161   1.248
199   K        -0.229  -0.188  -0.040  -0.644  -0.573  -0.317  -0.654  -0.588  -0.357
200   N        -0.627  -0.688  -0.661  -0.443  -0.514  -0.498  -0.802  -0.843  -0.808
201   K        -0.326  -0.405  -0.619  -0.313  -0.409  -0.706  -0.355  -0.457  -0.749
202   K         1.023   1.073   1.132   0.889   0.966   1.070   1.098   1.161   1.248
203   Y         0.332   0.226   0.085   0.564   0.411   0.126   0.315   0.145  -0.125
204   Y         1.023   1.073   1.132   1.203   1.266   1.349   1.098   1.161   1.248
205   L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
206   V         1.023   1.073   1.132   1.094   1.158   1.252   1.098   1.161   1.248
207   L         1.023   1.073   1.132   0.874   0.959   1.056   1.098   1.161   1.248
208   S        -0.763  -0.854  -0.691  -0.925  -1.024  -0.750  -1.026  -1.087  -0.850
209   S        -0.763  -0.740  -0.669  -1.019  -0.917  -0.808  -1.026  -0.929  -0.820
210   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
211   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   Q        -1.819  -1.745  -1.574  -1.625  -1.518  -1.281  -1.676  -1.558  -1.308
215   G        -1.717  -1.422  -1.537  -1.867  -1.447  -1.560  -1.585  -1.257  -1.278
216   E        -1.717  -1.751  -1.567  -1.701  -1.769  -1.470  -1.585  -1.562  -1.303
217   E        -1.399  -1.276  -1.184  -1.596  -1.398  -1.240  -1.473  -1.295  -1.133
218   Q        -1.201  -1.292  -1.181  -1.145  -1.316  -1.151  -1.249  -1.321  -1.130
219   V        -0.763  -0.796  -0.677  -0.897  -0.936  -0.765  -1.026  -1.000  -0.830
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   N         0.332   0.146   0.077   0.530   0.272   0.115   0.315   0.013  -0.139
226   L        -0.326  -0.619  -0.644  -0.323  -0.714  -0.743  -0.355  -0.748  -0.783
227   D        -0.763  -0.636  -0.676  -1.000  -0.840  -0.827  -1.026  -0.866  -0.833
228   G         0.332   0.146   0.077   0.257  -0.014  -0.126   0.315   0.013  -0.139
229   V        -0.627  -0.688  -0.661  -0.602  -0.655  -0.656  -0.802  -0.843  -0.808
230   T        -1.717  -1.595  -1.555  -1.637  -1.472  -1.433  -1.585  -1.426  -1.293
231   M        -0.326  -0.619  -0.644  -0.074  -0.532  -0.638  -0.355  -0.748  -0.783
232   D         0.332   0.226   0.085   0.361   0.215  -0.045   0.315   0.145  -0.125
233   E        -0.945  -1.092  -1.151  -0.846  -1.078  -1.154  -0.914  -1.086  -1.096
234   E        -2.154  -2.024  -1.879  -1.965  -1.785  -1.573  -1.808  -1.645  -1.415
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   V        -2.154  -2.123  -1.892  -2.115  -2.120  -1.781  -1.808  -1.717  -1.424
238   N        -2.790  -2.624  -2.385  -2.552  -2.345  -1.986  -2.032  -1.855  -1.562
239   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   K        -1.836  -1.662  -1.566  -1.913  -1.646  -1.473  -1.696  -1.497  -1.303
241   K        -0.326  -0.619  -0.644  -0.373  -0.814  -0.890  -0.355  -0.748  -0.783
242   Q        -2.034  -1.661  -1.842  -2.029  -1.473  -1.741  -1.696  -1.300  -1.387
243   L        -2.034  -2.004  -1.873  -2.000  -1.972  -1.733  -1.696  -1.629  -1.410
244   R        -0.945  -0.889  -1.126  -0.849  -0.793  -1.157  -0.914  -0.833  -1.069
245   Q        -0.945  -0.586  -1.087  -0.870  -0.400  -1.030  -0.914  -0.457  -1.026
246   R        -1.201  -1.243  -1.177  -1.455  -1.574  -1.429  -1.249  -1.280  -1.126
247   L        -1.717  -1.557  -1.543  -1.899  -1.632  -1.591  -1.585  -1.383  -1.283
248   K        -0.719  -0.551  -0.670  -0.884  -0.613  -0.809  -0.905  -0.651  -0.818
249   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   K         0.106   0.247   0.034  -0.073   0.158  -0.235  -0.047   0.180  -0.218
252   D        -2.154  -2.086  -1.886  -2.311  -2.147  -1.859  -1.808  -1.694  -1.420
253   K        -2.472  -2.310  -2.144  -2.504  -2.261  -2.009  -1.920  -1.742  -1.495
254   E        -0.326  -0.619  -0.644  -0.190  -0.606  -0.689  -0.355  -0.748  -0.783
255   S        -0.326  -0.405  -0.619  -0.289  -0.412  -0.740  -0.355  -0.457  -0.749
256   A        -1.399  -1.425  -1.195  -1.699  -1.693  -1.336  -1.473  -1.440  -1.145
257   K         0.332   0.146   0.077   0.266   0.013  -0.107   0.315   0.013  -0.139
258   S        -2.154  -2.003  -1.876  -2.129  -1.915  -1.713  -1.808  -1.627  -1.413
259   F        -0.883  -0.909  -0.725  -0.803  -0.825  -0.561  -1.137  -1.150  -0.891
260   I         1.023   1.073   1.132   1.055   1.110   1.217   1.098   1.161   1.248
261   L        -1.717  -1.532  -1.558  -1.571  -1.349  -1.360  -1.585  -1.382  -1.296
262   R        -0.326  -0.619  -0.644  -0.215  -0.618  -0.679  -0.355  -0.748  -0.783
263   K         1.023   1.073   1.132   0.889   0.966   1.070   1.098   1.161   1.248
264   K         1.023   1.073   1.132   0.889   0.966   1.070   1.098   1.161   1.248
265   E         1.023   1.073   1.132   1.035   1.108   1.199   1.098   1.161   1.248
266   L        -1.717  -1.617  -1.556  -1.745  -1.592  -1.452  -1.585  -1.439  -1.293
267   M        -0.326  -0.476  -0.625  -0.057  -0.271  -0.558  -0.355  -0.562  -0.756
268   K        -0.627  -0.582  -0.645  -0.752  -0.637  -0.787  -0.802  -0.695  -0.785
269   R        -0.248  -0.186  -0.040  -0.672  -0.571  -0.317  -0.690  -0.585  -0.356
270   R         0.332   0.226   0.085   0.355   0.206  -0.045   0.315   0.145  -0.125
271   G         1.023   1.073   1.132   0.886   0.950   1.068   1.098   1.161   1.248
272   R        -0.008  -0.037  -0.013  -0.170  -0.242  -0.247  -0.243  -0.305  -0.305
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   K        -2.034  -2.051  -1.881  -1.934  -1.912  -1.665  -1.696  -1.664  -1.416
275   V         1.023   1.073   1.132   1.094   1.158   1.252   1.098   1.161   1.248
276   A        -0.326  -0.619  -0.644  -0.268  -0.684  -0.756  -0.355  -0.748  -0.783
277   K        -2.154  -2.027  -1.876  -2.065  -1.907  -1.686  -1.808  -1.647  -1.413
278   D         0.332   0.226   0.085   0.394   0.258   0.043   0.315   0.145  -0.125
279   S         1.023   1.073   1.132   0.947   1.017   1.122   1.098   1.161   1.248
280   K         1.023   1.073   1.132   0.889   0.966   1.070   1.098   1.161   1.248
281   F        -0.008  -0.138  -0.031   0.054  -0.168  -0.018  -0.243  -0.493  -0.338
282   T         0.332   0.146   0.077   0.479   0.197   0.059   0.315   0.013  -0.139
283   G        -0.008   0.081   0.010  -0.250  -0.114  -0.245  -0.243  -0.096  -0.262
284   R         1.023   1.073   1.132   0.993   1.059   1.162   1.098   1.161   1.248
285   K         0.332   0.146   0.077   0.266   0.013  -0.107   0.315   0.013  -0.139
286   R         1.023   1.073   1.132   0.993   1.059   1.162   1.098   1.161   1.248
287   R         0.332   0.146   0.077   0.355   0.081  -0.060   0.315   0.013  -0.139
288   H        -1.519  -1.545  -1.548  -1.192  -1.313  -1.273  -1.361  -1.374  -1.286
289   R        -1.201  -1.348  -1.178  -1.304  -1.513  -1.270  -1.249  -1.357  -1.127
290   F         1.023   1.073   1.132   1.121   1.198   1.276   1.098   1.161   1.248
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25627
Output conservation file - output/P25627
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
