1     M         2.087   2.162   2.279   2.343   2.463   2.659   2.409   2.538   2.775
2     N        -1.121  -0.989  -1.049  -1.072  -0.869  -0.954  -0.987  -0.850  -0.871
3     D        -1.121  -1.096  -1.069  -1.218  -1.190  -1.203  -0.987  -0.944  -0.888
4     T        -1.121  -1.162  -1.084  -1.241  -1.291  -1.171  -0.987  -1.005  -0.903
5     L        -0.670  -0.554  -0.583  -1.085  -0.934  -0.975  -0.744  -0.590  -0.622
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     S        -0.065  -0.038   0.012  -0.077  -0.037   0.039  -0.328  -0.291  -0.232
10    S         0.120   0.124   0.072   0.304   0.328   0.212  -0.043  -0.039  -0.137
11    F        -0.065   0.045   0.005  -0.194   0.000  -0.137  -0.328  -0.162  -0.243
12    L         0.923   1.042   0.954   0.573   0.725   0.586   0.767   0.973   0.758
13    N        -0.065  -0.044   0.005   0.076   0.133   0.171  -0.328  -0.302  -0.243
14    -        -0.782  -0.741  -0.659  -0.879  -0.780  -0.696  -0.875  -0.817  -0.714
15    -        -1.622  -1.577  -1.519  -1.360  -1.357  -1.197  -1.240  -1.184  -1.101
16    -        -1.143  -1.125  -1.089  -0.888  -0.869  -0.785  -0.997  -0.968  -0.905
17    R         0.109   0.077   0.104   0.232   0.204   0.215  -0.093  -0.117  -0.101
18    N         1.238   1.128   1.097   1.465   1.338   1.283   1.337   1.133   1.050
19    E        -1.121  -1.106  -1.060  -0.716  -0.633  -0.590  -0.987  -0.956  -0.881
20    A         0.849   0.773   0.844   0.540   0.378   0.453   0.622   0.436   0.522
21    L        -0.556  -0.400  -0.507  -0.879  -0.653  -0.797  -0.629  -0.419  -0.535
22    G        -0.711  -0.642  -0.610  -0.615  -0.497  -0.443  -0.808  -0.724  -0.664
23    L         0.439   0.394   0.239   0.422   0.383   0.114   0.443   0.365   0.129
24    N         0.439   0.229   0.189   0.715   0.410   0.334   0.443   0.123   0.048
25    P         1.238   1.362   1.140   1.515   1.706   1.427   1.337   1.541   1.135
26    P         0.291   0.189   0.121   0.489   0.331   0.179   0.220   0.053  -0.060
27    H        -0.665  -0.684  -0.627  -0.449  -0.455  -0.383  -0.753  -0.761  -0.678
28    G        -1.622  -1.576  -1.519  -1.365  -1.253  -1.202  -1.240  -1.181  -1.101
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    L        -0.670  -0.644  -0.638  -1.024  -1.014  -0.986  -0.744  -0.702  -0.689
31    D        -0.301  -0.456  -0.500   0.097  -0.098  -0.190  -0.272  -0.470  -0.518
32    M        -1.531  -1.511  -1.468  -1.304  -1.269  -1.238  -1.165  -1.134  -1.059
33    H         1.238   1.128   1.097   1.523   1.381   1.315   1.337   1.133   1.050
34    I         0.674   0.705   0.811   0.185   0.166   0.341   0.265   0.293   0.451
35    T         0.439   0.229   0.189   0.661   0.397   0.321   0.443   0.123   0.048
36    K        -0.966  -0.887  -1.019  -0.538  -0.422  -0.612  -0.808  -0.711  -0.832
37    R         0.109   0.079   0.104   0.330   0.302   0.325  -0.093  -0.114  -0.094
38    G         1.238   1.128   1.097   1.331   1.190   1.139   1.337   1.133   1.050
39    S         2.087   2.162   2.279   2.047   2.143   2.351   2.409   2.538   2.775
40    D         0.439   0.389   0.227   0.774   0.735   0.477   0.443   0.358   0.109
41    W         1.238   1.128   1.097   1.520   1.380   1.356   1.337   1.133   1.050
42    L         1.238   1.128   1.097   1.082   0.921   0.914   1.337   1.133   1.050
43    W         2.087   2.162   2.279   2.257   2.369   2.569   2.409   2.538   2.775
44    A         2.087   2.162   2.279   1.923   2.043   2.222   2.409   2.538   2.775
45    V         0.849   0.854   0.874   0.554   0.549   0.524   0.622   0.604   0.587
46    F         1.238   1.172   1.116   1.196   1.115   1.044   1.337   1.215   1.087
47    A         0.674   0.769   0.842   0.265   0.412   0.513   0.265   0.429   0.518
48    V        -0.301  -0.255  -0.409  -0.272  -0.236  -0.437  -0.272  -0.209  -0.399
49    F         2.087   2.162   2.279   1.945   2.049   2.244   2.409   2.538   2.775
50    G        -0.146  -0.101  -0.015  -0.598  -0.565  -0.444  -0.450  -0.389  -0.277
51    F         0.109   0.173   0.108  -0.241  -0.193  -0.254  -0.093  -0.015  -0.100
52    I        -0.966  -1.001  -1.013  -0.974  -0.986  -1.012  -0.808  -0.842  -0.826
53    L        -0.556  -0.455  -0.537  -0.666  -0.523  -0.622  -0.629  -0.514  -0.578
54    L        -0.146  -0.087  -0.030  -0.614  -0.545  -0.475  -0.450  -0.367  -0.296
55    C         0.439   0.578   0.291   0.496   0.694   0.318   0.443   0.658   0.211
56    Y        -0.556  -0.657  -0.581  -0.407  -0.614  -0.497  -0.629  -0.721  -0.624
57    V        -1.941  -1.890  -1.845  -2.045  -1.911  -1.910  -1.344  -1.286  -1.212
58    V        -0.556  -0.577  -0.554  -0.921  -1.021  -0.974  -0.629  -0.650  -0.600
59    M        -0.556  -0.438  -0.523  -0.808  -0.690  -0.741  -0.629  -0.499  -0.563
60    F        -0.301  -0.401  -0.477  -0.191  -0.360  -0.417  -0.272  -0.407  -0.488
61    F        -0.556  -0.560  -0.561  -0.795  -0.825  -0.835  -0.629  -0.612  -0.603
62    I        -0.556  -0.542  -0.539  -0.625  -0.590  -0.547  -0.629  -0.591  -0.573
63    A        -0.556  -0.560  -0.561  -0.675  -0.669  -0.671  -0.629  -0.612  -0.603
64    E        -1.121  -1.089  -1.073  -0.987  -0.995  -0.915  -0.987  -0.941  -0.891
65    N        -1.622  -1.565  -1.519  -1.654  -1.504  -1.503  -1.240  -1.173  -1.101
66    K         0.109   0.079   0.104   0.367   0.367   0.401  -0.093  -0.114  -0.094
67    G         0.008   0.089   0.057   0.026   0.149   0.127  -0.272  -0.169  -0.185
68    S        -0.966  -1.047  -1.045  -0.610  -0.692  -0.657  -0.808  -0.887  -0.860
69    R         0.109   0.078   0.095   0.248   0.241   0.229  -0.093  -0.114  -0.111
70    L        -0.301  -0.310  -0.436  -0.415  -0.449  -0.625  -0.272  -0.285  -0.434
71    T        -0.556  -0.657  -0.581  -0.271  -0.363  -0.256  -0.629  -0.721  -0.624
72    R        -0.301  -0.288  -0.442   0.179   0.218   0.017  -0.272  -0.251  -0.442
73    Y        -0.966  -0.913  -1.023  -0.802  -0.757  -0.955  -0.808  -0.743  -0.837
74    A        -0.556  -0.657  -0.581  -0.951  -1.133  -1.007  -0.629  -0.721  -0.624
75    L        -0.966  -1.023  -1.021  -1.074  -1.183  -1.157  -0.808  -0.864  -0.835
76    A        -0.556  -0.386  -0.500  -0.744  -0.465  -0.638  -0.629  -0.407  -0.523
77    P        -0.711  -0.726  -0.619  -0.911  -0.972  -0.814  -0.808  -0.802  -0.671
78    A         0.694   0.752   0.838   0.529   0.649   0.734   0.307   0.392   0.510
79    F         0.694   0.752   0.838   0.141   0.186   0.337   0.307   0.392   0.510
80    L         0.694   0.752   0.838   0.173   0.223   0.364   0.307   0.392   0.510
81    I        -0.006   0.125   0.067  -0.128   0.076   0.010  -0.267  -0.076  -0.152
82    T        -0.556  -0.452  -0.530  -0.492  -0.345  -0.467  -0.629  -0.510  -0.572
83    F        -0.556  -0.477  -0.563  -0.808  -0.773  -0.823  -0.629  -0.548  -0.609
84    F         0.109   0.263   0.150  -0.145   0.106  -0.080  -0.093   0.144  -0.020
85    E        -1.121  -1.163  -1.100  -1.048  -1.127  -1.004  -0.987  -1.006  -0.917
86    F        -1.121  -1.173  -1.098  -1.161  -1.163  -1.072  -0.987  -1.014  -0.915
87    F        -0.301  -0.321  -0.455  -0.331  -0.418  -0.602  -0.272  -0.298  -0.459
88    A        -0.301  -0.128  -0.380  -0.242   0.008  -0.340  -0.272  -0.032  -0.361
89    F         1.238   1.367   1.149   1.431   1.602   1.314   1.337   1.550   1.152
90    F         1.238   1.409   1.150   1.211   1.426   1.124   1.337   1.620   1.153
91    T         1.238   1.172   1.116   1.339   1.275   1.161   1.337   1.215   1.087
92    Y         0.849   0.773   0.844   0.963   0.825   0.949   0.622   0.436   0.522
93    A         2.087   2.162   2.279   1.923   2.043   2.222   2.409   2.538   2.775
94    S         0.109   0.002   0.060   0.028  -0.126  -0.046  -0.093  -0.242  -0.173
95    D         1.238   1.367   1.149   1.492   1.686   1.413   1.337   1.550   1.152
96    L         1.238   1.128   1.097   1.082   0.921   0.914   1.337   1.133   1.050
97    G         1.238   1.172   1.116   1.310   1.235   1.131   1.337   1.215   1.087
98    W         0.109   0.078   0.095   0.221   0.151   0.173  -0.093  -0.114  -0.111
99    T        -0.301  -0.456  -0.500  -0.041  -0.218  -0.325  -0.272  -0.470  -0.518
100   G        -1.121  -1.163  -1.100  -0.946  -1.007  -0.913  -0.987  -1.006  -0.917
101   V        -0.301  -0.100  -0.417  -0.214   0.084  -0.366  -0.272   0.004  -0.409
102   Q        -0.670  -0.644  -0.638  -0.588  -0.527  -0.600  -0.744  -0.702  -0.689
103   A        -0.665  -0.663  -0.616  -0.921  -0.905  -0.836  -0.753  -0.741  -0.666
104   E         1.155   1.027   1.027   1.365   1.250   1.212   1.193   0.945   0.908
105   F         1.238   1.172   1.116   1.222   1.147   1.094   1.337   1.215   1.087
106   N         0.439   0.364   0.223   0.758   0.658   0.469   0.443   0.324   0.103
107   H         0.439   0.229   0.189   0.840   0.556   0.492   0.443   0.123   0.048
108   V         0.674   0.718   0.814   0.206   0.270   0.394   0.265   0.321   0.458
109   K        -1.531  -1.527  -1.493  -1.304  -1.295  -1.241  -1.165  -1.146  -1.081
110   V        -0.556  -0.657  -0.581  -0.572  -0.684  -0.591  -0.629  -0.721  -0.624
111   S        -1.244  -1.196  -1.132  -1.034  -0.962  -0.857  -1.094  -1.032  -0.946
112   K        -0.670  -0.560  -0.580  -0.483  -0.309  -0.343  -0.744  -0.604  -0.619
113   S        -0.782  -0.723  -0.659  -0.961  -0.837  -0.782  -0.875  -0.797  -0.714
114   I        -0.065   0.021   0.035  -0.447  -0.334  -0.330  -0.328  -0.201  -0.196
115   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   G         0.439   0.229   0.189   0.620   0.335   0.270   0.443   0.123   0.048
121   I        -0.966  -0.884  -0.980  -1.067  -0.924  -1.129  -0.808  -0.707  -0.790
122   R         2.087   2.162   2.279   2.272   2.395   2.585   2.409   2.538   2.775
123   Q         1.238   1.128   1.097   1.590   1.482   1.447   1.337   1.133   1.050
124   I         0.849   0.842   0.862   0.616   0.577   0.563   0.622   0.580   0.561
125   F         1.238   1.128   1.097   1.211   1.066   1.045   1.337   1.133   1.050
126   Y         1.238   1.172   1.116   1.482   1.401   1.354   1.337   1.215   1.087
127   S        -0.146  -0.097  -0.017  -0.552  -0.489  -0.380  -0.450  -0.382  -0.279
128   K         1.238   1.128   1.097   1.548   1.425   1.394   1.337   1.133   1.050
129   Y         0.674   0.773   0.842   0.442   0.612   0.707   0.265   0.436   0.519
130   I         0.008   0.098   0.071  -0.213  -0.105  -0.076  -0.272  -0.159  -0.166
131   A        -0.301  -0.436  -0.492  -0.291  -0.489  -0.585  -0.272  -0.447  -0.508
132   W         2.087   2.162   2.279   2.257   2.369   2.569   2.409   2.538   2.775
133   F         0.439   0.229   0.189   0.367   0.013  -0.074   0.443   0.123   0.048
134   L         0.109  -0.005   0.056  -0.270  -0.478  -0.382  -0.093  -0.254  -0.180
135   S        -0.556  -0.550  -0.561  -0.585  -0.555  -0.584  -0.629  -0.604  -0.602
136   W         0.849   0.773   0.844   0.859   0.661   0.752   0.622   0.436   0.522
137   P         2.087   2.162   2.279   2.241   2.375   2.553   2.409   2.538   2.775
138   C        -0.711  -0.645  -0.608  -0.913  -0.876  -0.819  -0.808  -0.728  -0.660
139   L        -0.556  -0.657  -0.581  -0.901  -1.068  -0.968  -0.629  -0.721  -0.624
140   L         0.849   0.773   0.844   0.457   0.273   0.391   0.622   0.436   0.522
141   F        -0.556  -0.657  -0.579  -0.888  -1.082  -0.977  -0.629  -0.722  -0.624
142   L        -0.556  -0.566  -0.559  -0.823  -0.827  -0.799  -0.629  -0.640  -0.604
143   I        -0.556  -0.657  -0.579  -0.701  -0.862  -0.730  -0.629  -0.722  -0.624
144   E        -0.301  -0.401  -0.477   0.091  -0.019  -0.130  -0.272  -0.407  -0.488
145   L        -0.556  -0.550  -0.551  -0.764  -0.727  -0.732  -0.629  -0.604  -0.587
146   A        -0.966  -1.020  -1.046  -1.091  -1.199  -1.272  -0.808  -0.861  -0.860
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   A        -0.966  -1.021  -1.046  -0.857  -0.964  -1.039  -0.808  -0.861  -0.861
150   S        -1.121  -0.967  -1.048  -0.943  -0.732  -0.806  -0.987  -0.821  -0.870
151   T         0.849   0.773   0.844   0.731   0.570   0.632   0.622   0.436   0.522
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -0.065   0.025   0.028  -0.219  -0.064  -0.096  -0.328  -0.193  -0.208
154   -        -0.782  -0.729  -0.659  -1.001  -0.875  -0.823  -0.875  -0.804  -0.714
155   -        -0.065  -0.068  -0.009  -0.192  -0.246  -0.131  -0.328  -0.341  -0.265
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   T        -0.096  -0.079  -0.002  -0.484  -0.494  -0.353  -0.393  -0.365  -0.261
158   G        -0.670  -0.636  -0.627  -0.645  -0.553  -0.600  -0.744  -0.692  -0.676
159   E        -0.096  -0.045  -0.001  -0.052   0.071   0.103  -0.393  -0.322  -0.258
160   N        -0.096  -0.032   0.002  -0.162  -0.055  -0.004  -0.393  -0.306  -0.255
161   D        -1.244  -1.219  -1.132  -1.050  -0.968  -0.874  -1.094  -1.052  -0.946
162   D        -0.096  -0.079  -0.002  -0.060   0.011   0.094  -0.393  -0.365  -0.261
163   I         0.120   0.193   0.072  -0.057   0.040  -0.192  -0.043   0.067  -0.138
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   S        -0.006   0.093   0.039  -0.052   0.079   0.025  -0.267  -0.119  -0.197
167   A        -0.187  -0.130  -0.035  -0.635  -0.553  -0.409  -0.510  -0.430  -0.304
168   L         0.291   0.417   0.180   0.046   0.197  -0.161   0.220   0.411   0.035
169   D        -0.665  -0.702  -0.625  -0.693  -0.731  -0.660  -0.753  -0.779  -0.676
170   M        -0.006   0.036   0.033  -0.330  -0.316  -0.240  -0.267  -0.227  -0.214
171   V        -1.143  -1.118  -1.104  -1.474  -1.467  -1.467  -0.997  -0.961  -0.919
172   H        -1.143  -1.132  -1.114  -0.753  -0.731  -0.707  -0.997  -0.975  -0.929
173   S        -1.121  -1.076  -1.074  -1.157  -1.086  -1.094  -0.987  -0.929  -0.892
174   L         0.291   0.189   0.121   0.150  -0.049  -0.100   0.220   0.053  -0.060
175   L        -0.485  -0.492  -0.548  -0.768  -0.832  -0.917  -0.510  -0.523  -0.579
176   I        -0.485  -0.486  -0.527  -0.600  -0.629  -0.700  -0.510  -0.515  -0.552
177   Q        -0.665  -0.663  -0.616  -0.342  -0.333  -0.243  -0.753  -0.741  -0.666
178   I        -1.121  -1.025  -1.049  -1.152  -1.032  -1.030  -0.987  -0.881  -0.871
179   V        -1.531  -1.452  -1.462  -1.533  -1.356  -1.431  -1.165  -1.081  -1.054
180   G        -1.121  -1.173  -1.098  -1.263  -1.351  -1.252  -0.987  -1.014  -0.915
181   T        -0.556  -0.553  -0.562  -0.631  -0.650  -0.675  -0.629  -0.627  -0.609
182   L         0.008  -0.018   0.042  -0.190  -0.220  -0.111  -0.272  -0.287  -0.203
183   F        -0.556  -0.432  -0.531  -0.704  -0.563  -0.670  -0.629  -0.492  -0.572
184   W        -0.556  -0.532  -0.559  -0.420  -0.408  -0.451  -0.629  -0.590  -0.602
185   V         1.238   1.128   1.097   1.178   1.035   0.977   1.337   1.133   1.050
186   V         0.008  -0.018   0.042  -0.451  -0.485  -0.394  -0.272  -0.287  -0.203
187   S        -0.301  -0.285  -0.458  -0.094  -0.040  -0.324  -0.272  -0.254  -0.463
188   L         1.238   1.172   1.116   1.082   0.983   0.942   1.337   1.215   1.087
189   L         2.087   2.162   2.279   1.816   1.902   2.110   2.409   2.538   2.775
190   V         0.008  -0.044   0.040  -0.329  -0.404  -0.289  -0.272  -0.319  -0.206
191   G         0.849   0.773   0.844   0.694   0.521   0.591   0.622   0.436   0.522
192   S         0.109   0.244   0.132  -0.119   0.085  -0.094  -0.093   0.110  -0.061
193   L         0.439   0.404   0.238   0.329   0.262   0.050   0.443   0.388   0.127
194   I         0.439   0.229   0.189   0.486   0.182   0.101   0.443   0.123   0.048
195   K        -1.531  -1.452  -1.462  -1.106  -1.003  -0.990  -1.165  -1.081  -1.054
196   S         2.087   2.162   2.279   2.047   2.143   2.351   2.409   2.538   2.775
197   T        -0.301  -0.436  -0.492  -0.029  -0.188  -0.292  -0.272  -0.447  -0.508
198   Y         2.087   2.162   2.279   2.210   2.313   2.520   2.409   2.538   2.775
199   K         1.238   1.362   1.140   1.548   1.726   1.460   1.337   1.541   1.135
200   W         1.238   1.333   1.137   1.478   1.614   1.341   1.337   1.494   1.128
201   G         1.238   1.128   1.097   1.310   1.167   1.099   1.337   1.133   1.050
202   Y         1.238   1.172   1.116   1.411   1.303   1.219   1.337   1.215   1.087
203   Y         0.849   0.844   0.869   0.664   0.634   0.680   0.622   0.584   0.578
204   T         0.439   0.229   0.189   0.595   0.305   0.197   0.443   0.123   0.048
205   I         1.238   1.367   1.149   1.175   1.346   1.059   1.337   1.550   1.152
206   G         0.109   0.079   0.104  -0.087  -0.114  -0.092  -0.093  -0.114  -0.094
207   A         0.008  -0.044   0.040  -0.383  -0.452  -0.341  -0.272  -0.319  -0.206
208   V        -0.966  -0.909  -0.974  -1.120  -1.061  -1.186  -0.808  -0.734  -0.784
209   A         0.109   0.078   0.095  -0.146  -0.162  -0.173  -0.093  -0.114  -0.111
210   M        -0.556  -0.657  -0.581  -0.146  -0.257  -0.137  -0.629  -0.721  -0.624
211   L         0.439   0.229   0.189   0.273  -0.077  -0.133   0.443   0.123   0.048
212   V        -0.556  -0.568  -0.547  -0.856  -0.881  -0.870  -0.629  -0.623  -0.582
213   T        -0.556  -0.455  -0.537  -0.879  -0.759  -0.870  -0.629  -0.514  -0.578
214   Q        -1.121  -1.145  -1.089  -0.899  -1.005  -0.903  -0.987  -0.993  -0.907
215   G        -1.531  -1.526  -1.502  -1.492  -1.550  -1.484  -1.165  -1.146  -1.088
216   V        -1.531  -1.537  -1.491  -1.449  -1.378  -1.342  -1.165  -1.154  -1.079
217   I        -1.121  -1.159  -1.079  -1.130  -1.177  -1.032  -0.987  -1.003  -0.898
218   C        -1.121  -1.006  -1.048  -1.262  -1.136  -1.136  -0.987  -0.865  -0.871
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   Q        -1.121  -1.161  -1.074  -0.927  -0.965  -0.815  -0.987  -1.005  -0.894
224   R         0.008  -0.044   0.040   0.029  -0.011   0.126  -0.272  -0.319  -0.206
225   Q        -1.121  -1.163  -1.100  -0.921  -0.991  -0.867  -0.987  -1.006  -0.917
226   F        -0.966  -1.020  -1.046  -0.847  -0.941  -0.937  -0.808  -0.861  -0.860
227   F         0.849   0.981   0.972   0.659   0.855   0.831   0.622   0.856   0.796
228   N        -1.531  -1.474  -1.464  -1.312  -1.199  -1.200  -1.165  -1.099  -1.056
229   L        -0.146  -0.087  -0.029  -0.654  -0.604  -0.499  -0.450  -0.367  -0.296
230   K        -0.556  -0.657  -0.579  -0.213  -0.317  -0.213  -0.629  -0.722  -0.624
231   T         0.008  -0.018   0.042  -0.080  -0.081   0.016  -0.272  -0.287  -0.203
232   R        -0.556  -0.568  -0.547  -0.530  -0.551  -0.495  -0.629  -0.623  -0.582
233   G        -0.966  -0.913  -1.023  -0.832  -0.769  -0.946  -0.808  -0.743  -0.837
234   F        -1.531  -1.526  -1.502  -1.473  -1.436  -1.412  -1.165  -1.146  -1.088
235   N         0.439   0.401   0.244   0.679   0.609   0.367   0.443   0.375   0.137
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   A         0.120   0.021   0.057  -0.038  -0.207  -0.156  -0.043  -0.199  -0.162
239   L        -0.670  -0.616  -0.583  -0.840  -0.787  -0.699  -0.744  -0.672  -0.622
240   M        -1.531  -1.455  -1.464  -1.333  -1.167  -1.260  -1.165  -1.083  -1.056
241   L         0.109   0.060   0.089  -0.260  -0.356  -0.308  -0.093  -0.145  -0.125
242   C        -0.301  -0.284  -0.429  -0.207  -0.208  -0.400  -0.272  -0.246  -0.425
243   T        -1.531  -1.541  -1.478  -1.733  -1.747  -1.658  -1.165  -1.157  -1.068
244   C        -1.531  -1.509  -1.481  -1.309  -1.260  -1.200  -1.165  -1.132  -1.070
245   M        -1.121  -1.163  -1.100  -0.972  -1.081  -0.945  -0.987  -1.006  -0.917
246   V        -1.121  -1.173  -1.072  -1.164  -1.170  -1.038  -0.987  -1.014  -0.892
247   I         0.008  -0.040   0.056  -0.423  -0.523  -0.365  -0.272  -0.312  -0.184
248   V         0.439   0.229   0.189   0.381   0.049  -0.050   0.443   0.123   0.048
249   W         2.087   2.162   2.279   2.257   2.369   2.569   2.409   2.538   2.775
250   -         0.120   0.009   0.056  -0.086  -0.305  -0.276  -0.043  -0.217  -0.164
251   L         1.238   1.375   1.153   1.032   1.199   0.908   1.337   1.564   1.160
252   Y         2.087   2.162   2.279   2.210   2.313   2.520   2.409   2.538   2.775
253   F         0.109   0.079   0.104   0.176   0.178   0.185  -0.093  -0.114  -0.094
254   I         0.109   0.078   0.095  -0.111  -0.148  -0.163  -0.093  -0.114  -0.111
255   C         0.674   0.726   0.820   0.566   0.650   0.770   0.265   0.337   0.471
256   W         2.087   2.162   2.279   2.257   2.369   2.569   2.409   2.538   2.775
257   G         1.238   1.128   1.097   1.323   1.183   1.124   1.337   1.133   1.050
258   L         0.849   0.872   0.887   0.435   0.434   0.438   0.622   0.640   0.615
259   S         2.087   2.162   2.279   2.047   2.143   2.351   2.409   2.538   2.775
260   D         0.849   0.868   0.885   0.920   0.986   0.961   0.622   0.633   0.612
261   G         2.087   2.162   2.279   2.093   2.216   2.398   2.409   2.538   2.775
262   G         1.238   1.128   1.097   1.293   1.135   1.064   1.337   1.133   1.050
263   N         2.087   2.162   2.279   2.221   2.349   2.531   2.409   2.538   2.775
264   R         0.109   0.268   0.123   0.075   0.303   0.131  -0.093   0.148  -0.073
265   I         2.087   2.162   2.279   2.002   2.110   2.304   2.409   2.538   2.775
266   Q         0.439   0.229   0.189   0.799   0.502   0.417   0.443   0.123   0.048
267   P         1.238   1.172   1.116   1.463   1.398   1.290   1.337   1.215   1.087
268   D         0.439   0.229   0.189   0.746   0.462   0.363   0.443   0.123   0.048
269   G         0.109   0.019   0.068   0.081  -0.056   0.032  -0.093  -0.223  -0.162
270   E         1.238   1.172   1.116   1.437   1.390   1.279   1.337   1.215   1.087
271   A         1.238   1.172   1.116   1.213   1.157   1.096   1.337   1.215   1.087
272   I         0.674   0.769   0.842   0.268   0.431   0.520   0.265   0.429   0.518
273   F         2.087   2.162   2.279   1.945   2.049   2.244   2.409   2.538   2.775
274   Y         1.238   1.172   1.116   1.431   1.333   1.258   1.337   1.215   1.087
275   G         1.238   1.128   1.097   1.331   1.190   1.139   1.337   1.133   1.050
276   V         1.238   1.367   1.149   1.223   1.401   1.101   1.337   1.550   1.152
277   L         2.087   2.162   2.279   1.816   1.902   2.110   2.409   2.538   2.775
278   D         2.087   2.162   2.279   2.254   2.394   2.566   2.409   2.538   2.775
279   L         1.238   1.172   1.116   1.036   0.926   0.854   1.337   1.215   1.087
280   C        -0.556  -0.657  -0.581  -0.567  -0.773  -0.644  -0.629  -0.721  -0.624
281   V        -0.966  -1.021  -1.046  -0.831  -0.899  -1.000  -0.808  -0.861  -0.861
282   F         1.238   1.172   1.116   1.175   1.082   1.005   1.337   1.215   1.087
283   A        -0.301  -0.262  -0.416  -0.157  -0.084  -0.349  -0.272  -0.218  -0.408
284   I        -1.121  -1.073  -1.068  -1.350  -1.274  -1.292  -0.987  -0.924  -0.886
285   Y        -1.531  -1.459  -1.461  -1.562  -1.519  -1.446  -1.165  -1.086  -1.053
286   P         0.439   0.229   0.189   0.737   0.445   0.357   0.443   0.123   0.048
287   C        -1.121  -1.090  -1.065  -1.064  -1.018  -0.940  -0.987  -0.938  -0.885
288   Y        -0.146  -0.113  -0.028  -0.413  -0.408  -0.269  -0.450  -0.409  -0.297
289   L         0.849   0.773   0.844   0.434   0.238   0.354   0.622   0.436   0.522
290   L        -1.121  -1.105  -1.067  -1.264  -1.250  -1.215  -0.987  -0.954  -0.887
291   I        -0.556  -0.530  -0.539  -0.543  -0.502  -0.545  -0.629  -0.582  -0.579
292   A        -0.966  -1.044  -1.032  -0.963  -1.097  -1.103  -0.808  -0.884  -0.846
293   V        -1.531  -1.527  -1.493  -1.602  -1.651  -1.551  -1.165  -1.146  -1.081
294   S        -1.531  -1.527  -1.493  -1.303  -1.242  -1.218  -1.165  -1.146  -1.081
295   R        -1.531  -1.455  -1.464  -1.120  -1.066  -1.012  -1.165  -1.083  -1.056
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -         0.120   0.155   0.109   0.118   0.164   0.138  -0.043   0.005  -0.079
298   -         1.051   0.982   1.006   1.256   1.158   1.179   1.008   0.859   0.865
299   -         0.120   0.009   0.056   0.250   0.069   0.119  -0.043  -0.217  -0.164
300   -         0.120   0.144   0.109   0.276   0.312   0.249  -0.043  -0.012  -0.079
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -         0.120   0.009   0.056  -0.035  -0.214  -0.166  -0.043  -0.217  -0.164
306   D         0.439   0.617   0.280   0.511   0.742   0.326   0.443   0.716   0.193
307   G        -1.121  -1.111  -1.075  -0.901  -0.851  -0.790  -0.987  -0.959  -0.893
308   K        -0.301  -0.426  -0.471   0.039  -0.150  -0.244  -0.272  -0.435  -0.479
309   L        -1.531  -1.511  -1.468  -1.473  -1.412  -1.354  -1.165  -1.134  -1.059
310   P        -1.121  -1.163  -1.100  -0.688  -0.723  -0.612  -0.987  -1.006  -0.917
311   R        -0.711  -0.655  -0.612  -0.507  -0.443  -0.342  -0.808  -0.735  -0.665
312   L        -1.121  -1.173  -1.070  -1.386  -1.500  -1.305  -0.987  -1.014  -0.890
313   S        -1.121  -0.983  -1.061  -0.719  -0.510  -0.610  -0.987  -0.833  -0.881
314   L         0.439   0.404   0.238   0.273   0.196  -0.048   0.443   0.388   0.127
315   T        -1.121  -1.163  -1.100  -0.892  -0.962  -0.852  -0.987  -1.006  -0.917
316   G        -1.531  -1.455  -1.464  -1.220  -1.149  -1.102  -1.165  -1.083  -1.056
317   G        -1.531  -1.527  -1.493  -1.107  -1.043  -1.033  -1.165  -1.146  -1.081
318   F        -1.531  -1.437  -1.455  -1.397  -1.262  -1.283  -1.165  -1.064  -1.049
319   S        -0.556  -0.484  -0.550  -0.331  -0.210  -0.299  -0.629  -0.556  -0.595
320   H        -0.966  -1.039  -1.024  -0.552  -0.683  -0.652  -0.808  -0.879  -0.838
321   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   A         0.923   1.068   0.969   0.731   0.958   0.797   0.767   1.022   0.790
324   T         0.652   0.707   0.811   0.481   0.577   0.719   0.220   0.297   0.452
325   D        -0.096   0.002   0.014  -0.066   0.090   0.112  -0.393  -0.267  -0.240
326   D         0.120   0.255   0.154   0.272   0.491   0.312  -0.043   0.162  -0.007
327   V        -1.143  -1.157  -1.114  -1.055  -1.023  -0.971  -0.997  -0.997  -0.929
328   E        -0.006  -0.065   0.024   0.062  -0.018   0.101  -0.267  -0.344  -0.227
329   D        -0.006   0.018   0.027   0.036   0.040   0.070  -0.267  -0.248  -0.223
330   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   T        -0.782  -0.738  -0.659  -0.765  -0.663  -0.577  -0.875  -0.813  -0.714
335   K         0.120   0.029   0.056   0.330   0.214   0.258  -0.043  -0.190  -0.164
336   E         0.694   0.708   0.811   0.659   0.660   0.813   0.307   0.301   0.452
337   A         1.051   1.165   1.045   0.992   1.156   0.995   1.008   1.201   0.945
338   V         1.051   0.955   0.995   0.989   0.860   0.926   1.008   0.805   0.843
339   P        -1.143  -1.132  -1.114  -0.910  -0.846  -0.882  -0.997  -0.975  -0.929
340   E         1.155   1.000   1.027   1.346   1.184   1.193   1.193   0.892   0.908
341   S        -0.006  -0.068   0.021  -0.142  -0.238  -0.123  -0.267  -0.338  -0.223
342   P         0.291   0.217   0.151   0.536   0.461   0.308   0.220   0.087  -0.013
343   R         0.291   0.162   0.121   0.599   0.420   0.331   0.220   0.009  -0.060
344   A        -0.665  -0.702  -0.625  -0.723  -0.828  -0.679  -0.753  -0.779  -0.676
345   S         0.291   0.162   0.121   0.332   0.104   0.050   0.220   0.009  -0.060
346   G         0.291   0.162   0.121   0.326   0.109   0.003   0.220   0.009  -0.060
347   E         0.694   0.770   0.838   0.635   0.791   0.853   0.307   0.431   0.510
348   T         2.087   2.162   2.279   2.129   2.268   2.436   2.409   2.538   2.775
349   A         1.051   0.923   0.970   0.977   0.809   0.866   1.008   0.742   0.791
350   I         0.694   0.770   0.838   0.309   0.418   0.509   0.307   0.431   0.510
351   H        -0.782  -0.740  -0.659  -0.642  -0.550  -0.450  -0.875  -0.816  -0.714
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -         0.923   1.007   0.947   0.836   0.968   0.824   0.767   0.906   0.744
361   -         0.923   1.007   0.947   0.744   0.873   0.771   0.767   0.906   0.744
362   -        -0.782  -0.729  -0.659  -0.807  -0.733  -0.621  -0.875  -0.804  -0.714
363   -         0.923   1.007   0.947   1.068   1.205   1.091   0.767   0.906   0.744
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -0.065  -0.082  -0.012  -0.223  -0.236  -0.143  -0.328  -0.363  -0.270
368   -        -0.782  -0.721  -0.659  -0.937  -0.907  -0.757  -0.875  -0.794  -0.714
369   A        -0.670  -0.658  -0.604  -0.727  -0.690  -0.621  -0.744  -0.724  -0.649
370   E        -1.244  -1.193  -1.132  -0.931  -0.896  -0.751  -1.094  -1.029  -0.946
371   Q        -1.622  -1.583  -1.519  -1.259  -1.190  -1.091  -1.240  -1.188  -1.101
372   A        -1.143  -1.169  -1.104  -0.870  -0.903  -0.804  -0.997  -1.007  -0.919
373   V        -1.143  -1.118  -1.070  -1.142  -1.107  -1.023  -0.997  -0.956  -0.886
374   E        -0.485  -0.537  -0.539  -0.220  -0.300  -0.299  -0.510  -0.572  -0.568
375   D        -1.143  -1.167  -1.101  -0.877  -0.885  -0.808  -0.997  -1.005  -0.917
376   T        -1.143  -1.167  -1.101  -0.839  -0.894  -0.780  -0.997  -1.005  -0.917
377   A        -0.485  -0.456  -0.504  -0.520  -0.459  -0.550  -0.510  -0.471  -0.523
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25619
Output conservation file - output/P25619
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
