1     M         2.436   2.444   2.535   2.726   2.737   2.883   2.756   2.766   2.907
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     K         1.565   1.590   1.494   1.523   1.559   1.427   1.557   1.599   1.368
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    T        -0.176  -0.173  -0.115  -0.293  -0.274  -0.197  -0.416  -0.410  -0.337
22    I        -0.452  -0.457  -0.464  -0.713  -0.722  -0.733  -0.482  -0.486  -0.476
23    I        -0.578  -0.593  -0.536  -0.696  -0.713  -0.627  -0.617  -0.627  -0.552
24    I         0.553   0.546   0.558   0.333   0.322   0.365   0.192   0.178   0.196
25    S        -0.786  -0.832  -0.826  -0.773  -0.852  -0.865  -0.617  -0.662  -0.639
26    D         2.436   2.444   2.535   2.405   2.416   2.557   2.756   2.766   2.907
27    F         1.349   1.377   1.361   1.456   1.499   1.467   1.137   1.188   1.094
28    D         2.436   2.444   2.535   2.405   2.416   2.557   2.756   2.766   2.907
29    E         0.696   0.661   0.623   0.580   0.513   0.452   0.462   0.396   0.323
30    T         2.436   2.444   2.535   2.494   2.504   2.647   2.756   2.766   2.907
31    I         1.014   0.974   0.816   1.090   1.041   0.827   1.002   0.937   0.661
32    T         2.436   2.444   2.535   2.494   2.504   2.647   2.756   2.766   2.907
33    R        -0.913  -0.910  -0.886  -0.716  -0.717  -0.675  -0.752  -0.747  -0.699
34    V        -1.248  -1.253  -1.215  -1.171  -1.174  -1.120  -0.887  -0.890  -0.830
35    D         2.436   2.444   2.535   2.405   2.416   2.557   2.756   2.766   2.907
36    T         2.436   2.444   2.535   2.494   2.504   2.647   2.756   2.766   2.907
37    I         1.014   0.981   0.838   1.019   0.979   0.752   1.002   0.948   0.697
38    C        -1.248  -1.253  -1.215  -0.990  -0.997  -0.920  -0.887  -0.890  -0.830
39    T        -0.452  -0.431  -0.451  -0.616  -0.598  -0.609  -0.482  -0.462  -0.465
40    I         0.427   0.450   0.489   0.008   0.046   0.089   0.058   0.094   0.127
41    A         0.696   0.692   0.648   0.785   0.771   0.699   0.462   0.453   0.367
42    K         0.427   0.450   0.470   0.253   0.297   0.287   0.058   0.092   0.094
43    L        -1.248  -1.238  -1.199  -1.060  -1.036  -0.999  -0.887  -0.878  -0.817
44    P         0.345   0.340   0.413   0.289   0.268   0.380  -0.077  -0.085   0.003
45    Y         1.014   0.958   0.813   1.291   1.214   0.995   1.002   0.912   0.657
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    L        -0.942  -0.927  -0.896  -0.765  -0.731  -0.699  -0.769  -0.754  -0.704
53    L        -0.559  -0.559  -0.524  -0.838  -0.834  -0.782  -0.592  -0.591  -0.538
54    N         0.589   0.618   0.573   0.431   0.469   0.408   0.289   0.320   0.241
55    P         0.481   0.495   0.498   0.490   0.505   0.492   0.117   0.129   0.125
56    R        -0.176  -0.158  -0.116  -0.303  -0.290  -0.218  -0.416  -0.397  -0.338
57    L        -0.913  -0.927  -0.888  -0.942  -0.956  -0.881  -0.752  -0.761  -0.701
58    K        -0.913  -0.899  -0.872  -0.931  -0.896  -0.885  -0.752  -0.739  -0.688
59    P         0.696   0.642   0.613   0.819   0.720   0.652   0.462   0.372   0.306
60    E        -1.248  -1.250  -1.201  -1.039  -1.036  -0.962  -0.887  -0.887  -0.819
61    W         1.349   1.377   1.361   1.549   1.594   1.549   1.137   1.188   1.094
62    G        -0.913  -0.906  -0.871  -1.007  -0.999  -0.951  -0.752  -0.744  -0.687
63    H        -0.243  -0.277  -0.368   0.158   0.108  -0.050  -0.212  -0.254  -0.357
64    F         0.696   0.642   0.613   0.739   0.649   0.586   0.462   0.372   0.306
65    T        -0.117  -0.120  -0.082  -0.277  -0.289  -0.231  -0.347  -0.352  -0.300
66    K        -0.117  -0.094  -0.070  -0.433  -0.394  -0.367  -0.347  -0.320  -0.284
67    T        -1.248  -1.234  -1.201  -1.303  -1.288  -1.240  -0.887  -0.874  -0.819
68    Y         2.436   2.444   2.535   2.614   2.625   2.769   2.756   2.766   2.907
69    M        -0.913  -0.912  -0.871  -0.730  -0.741  -0.658  -0.752  -0.749  -0.688
70    D        -0.578  -0.580  -0.533  -0.685  -0.682  -0.611  -0.617  -0.616  -0.550
71    G        -0.913  -0.884  -0.879  -0.727  -0.696  -0.678  -0.752  -0.727  -0.694
72    Y         1.014   1.062   0.855   1.355   1.417   1.154   1.002   1.074   0.725
73    H        -1.248  -1.245  -1.206  -1.136  -1.141  -1.081  -0.887  -0.883  -0.822
74    K        -0.452  -0.452  -0.461  -0.424  -0.419  -0.422  -0.482  -0.484  -0.475
75    Y        -0.786  -0.832  -0.828  -0.461  -0.526  -0.535  -0.617  -0.661  -0.640
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    K         0.092   0.071   0.059   0.092   0.078   0.064  -0.077  -0.097  -0.119
80    Y        -0.452  -0.399  -0.445  -0.369  -0.302  -0.340  -0.482  -0.423  -0.459
81    N        -0.452  -0.471  -0.456  -0.513  -0.543  -0.524  -0.482  -0.500  -0.468
82    G         0.010   0.020   0.001  -0.112  -0.103  -0.107  -0.212  -0.202  -0.206
83    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    I         0.397   0.372   0.441   0.098   0.066   0.161  -0.007  -0.041   0.043
99    S        -0.139  -0.155  -0.095  -0.108  -0.125  -0.037  -0.353  -0.375  -0.303
100   Q        -0.139  -0.104  -0.090  -0.350  -0.299  -0.281  -0.353  -0.308  -0.296
101   S        -0.674  -0.666  -0.598  -0.707  -0.686  -0.595  -0.698  -0.689  -0.606
102   N        -0.176  -0.184  -0.119  -0.304  -0.313  -0.211  -0.416  -0.421  -0.340
103   F        -1.248  -1.235  -1.196  -0.765  -0.746  -0.682  -0.887  -0.875  -0.815
104   N        -0.452  -0.447  -0.446  -0.375  -0.368  -0.358  -0.482  -0.479  -0.460
105   K         0.092   0.100   0.040  -0.050  -0.035  -0.147  -0.077  -0.067  -0.145
106   L        -0.452  -0.461  -0.460  -0.549  -0.565  -0.544  -0.482  -0.491  -0.474
107   F         0.092   0.113   0.061  -0.020   0.021  -0.051  -0.077  -0.040  -0.111
108   A        -0.578  -0.575  -0.531  -0.717  -0.715  -0.642  -0.617  -0.613  -0.549
109   D        -0.578  -0.593  -0.536  -0.720  -0.733  -0.650  -0.617  -0.627  -0.552
110   E        -0.243  -0.272  -0.346  -0.081  -0.128  -0.221  -0.212  -0.247  -0.330
111   L         0.553   0.543   0.572   0.204   0.206   0.259   0.192   0.188   0.221
112   K        -0.452  -0.500  -0.464  -0.524  -0.586  -0.530  -0.482  -0.528  -0.479
113   Y         0.553   0.546   0.552   0.516   0.508   0.510   0.192   0.187   0.192
114   Q         0.696   0.642   0.613   0.689   0.586   0.507   0.462   0.372   0.306
115   N        -1.248  -1.238  -1.208  -1.096  -1.088  -1.056  -0.887  -0.877  -0.824
116   H        -1.248  -1.238  -1.199  -0.972  -0.967  -0.899  -0.887  -0.878  -0.817
117   N        -0.117  -0.096  -0.074  -0.338  -0.316  -0.260  -0.347  -0.324  -0.288
118   R         0.092   0.096   0.030   0.223   0.223   0.110  -0.077  -0.076  -0.158
119   V        -0.913  -0.924  -0.885  -0.710  -0.720  -0.645  -0.752  -0.758  -0.699
120   V        -0.243  -0.266  -0.340  -0.088  -0.124  -0.247  -0.212  -0.241  -0.324
121   E         2.436   2.444   2.535   2.391   2.399   2.543   2.756   2.766   2.907
122   L         0.092   0.097   0.034   0.015   0.019  -0.056  -0.077  -0.069  -0.151
123   N        -0.452  -0.403  -0.449  -0.406  -0.341  -0.396  -0.482  -0.434  -0.462
124   S         2.436   2.444   2.535   2.430   2.442   2.583   2.756   2.766   2.907
125   V         0.092   0.101   0.042  -0.004   0.019  -0.074  -0.077  -0.061  -0.142
126   N        -0.452  -0.454  -0.458  -0.418  -0.424  -0.432  -0.482  -0.486  -0.472
127   E         0.553   0.563   0.551   0.361   0.369   0.362   0.192   0.196   0.186
128   I         0.092   0.074   0.045  -0.021  -0.060  -0.092  -0.077  -0.107  -0.138
129   T        -0.243  -0.200  -0.331  -0.171  -0.114  -0.314  -0.212  -0.162  -0.313
130   K        -0.243  -0.268  -0.347  -0.157  -0.197  -0.316  -0.212  -0.243  -0.332
131   Q         0.010   0.001  -0.007  -0.081  -0.094  -0.112  -0.212  -0.221  -0.214
132   Q        -0.578  -0.581  -0.527  -0.645  -0.650  -0.561  -0.617  -0.617  -0.545
133   I        -0.452  -0.501  -0.470  -0.531  -0.585  -0.533  -0.482  -0.530  -0.484
134   F         1.708   1.708   1.593   1.936   1.939   1.797   1.812   1.809   1.563
135   K        -0.578  -0.591  -0.536  -0.838  -0.852  -0.774  -0.617  -0.625  -0.553
136   S         0.361   0.343   0.204   0.569   0.539   0.328   0.327   0.299   0.099
137   I         0.345   0.366   0.419  -0.119  -0.088  -0.018  -0.077  -0.050   0.012
138   S         0.092   0.093   0.059   0.093   0.095   0.040  -0.077  -0.073  -0.120
139   L        -0.786  -0.771  -0.806  -0.821  -0.799  -0.876  -0.617  -0.602  -0.619
140   D        -0.913  -0.924  -0.877  -0.989  -1.008  -0.930  -0.752  -0.758  -0.692
141   Q        -0.913  -0.903  -0.873  -0.763  -0.755  -0.694  -0.752  -0.742  -0.689
142   M        -0.913  -0.896  -0.883  -0.825  -0.815  -0.771  -0.752  -0.737  -0.697
143   K        -1.248  -1.253  -1.215  -1.092  -1.119  -1.064  -0.887  -0.890  -0.830
144   T        -0.786  -0.801  -0.804  -0.659  -0.685  -0.686  -0.617  -0.632  -0.617
145   F        -0.134  -0.138  -0.083  -0.218  -0.226  -0.158  -0.362  -0.366  -0.297
146   A         0.759   0.773   0.683   0.818   0.829   0.699   0.597   0.615   0.445
147   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   N        -0.134  -0.149  -0.092  -0.255  -0.281  -0.209  -0.362  -0.378  -0.306
165   H        -0.134  -0.149  -0.092  -0.090  -0.120  -0.039  -0.362  -0.378  -0.306
166   E        -0.913  -0.925  -0.890  -0.849  -0.861  -0.809  -0.752  -0.759  -0.703
167   D        -0.786  -0.766  -0.801  -0.762  -0.729  -0.794  -0.617  -0.596  -0.614
168   C         0.427   0.459   0.480   0.284   0.329   0.347   0.058   0.108   0.112
169   L        -1.248  -1.238  -1.199  -1.272  -1.250  -1.216  -0.887  -0.878  -0.817
170   L         0.361   0.296   0.185   0.330   0.232   0.061   0.327   0.236   0.073
171   R         1.349   1.362   1.335   1.386   1.404   1.321   1.137   1.158   1.040
172   D        -0.786  -0.780  -0.820  -0.513  -0.505  -0.602  -0.617  -0.610  -0.633
173   G         1.708   1.733   1.605   1.889   1.919   1.776   1.812   1.851   1.586
174   F         0.361   0.354   0.214   0.634   0.620   0.412   0.327   0.316   0.114
175   K        -1.248  -1.232  -1.200  -1.159  -1.124  -1.090  -0.887  -0.873  -0.818
176   T         0.092   0.165   0.064  -0.009   0.100  -0.050  -0.077   0.019  -0.113
177   F         1.014   1.012   0.852   1.275   1.268   1.049   1.002   0.996   0.721
178   C        -0.913  -0.898  -0.872  -0.829  -0.810  -0.754  -0.752  -0.738  -0.688
179   S        -1.248  -1.211  -1.202  -1.052  -0.980  -0.995  -0.887  -0.855  -0.819
180   S        -0.913  -0.880  -0.878  -0.787  -0.733  -0.725  -0.752  -0.723  -0.693
181   V        -0.578  -0.567  -0.531  -0.514  -0.509  -0.443  -0.617  -0.606  -0.548
182   V        -0.032  -0.069  -0.039  -0.098  -0.157  -0.115  -0.240  -0.280  -0.242
183   K        -0.942  -0.944  -0.906  -0.842  -0.837  -0.777  -0.769  -0.769  -0.713
184   N        -0.559  -0.562  -0.526  -0.720  -0.718  -0.652  -0.592  -0.594  -0.539
185   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   E        -0.559  -0.558  -0.514  -0.661  -0.660  -0.584  -0.592  -0.590  -0.529
190   S        -0.559  -0.551  -0.527  -0.679  -0.664  -0.627  -0.592  -0.583  -0.541
191   D        -0.032  -0.067  -0.041  -0.043  -0.094  -0.080  -0.240  -0.276  -0.243
192   F        -0.032  -0.041  -0.037  -0.170  -0.188  -0.205  -0.240  -0.250  -0.242
193   Y        -0.117  -0.134  -0.093  -0.100  -0.115  -0.061  -0.347  -0.364  -0.311
194   V         0.553   0.538   0.566   0.262   0.246   0.276   0.192   0.181   0.211
195   L         0.696   0.684   0.621   0.453   0.429   0.317   0.462   0.440   0.320
196   S         2.436   2.444   2.535   2.430   2.442   2.583   2.756   2.766   2.907
197   I         0.361   0.395   0.228   0.480   0.521   0.266   0.327   0.372   0.133
198   N         2.436   2.444   2.535   2.549   2.566   2.703   2.756   2.766   2.907
199   W         2.436   2.444   2.535   2.726   2.737   2.883   2.756   2.766   2.907
200   S         1.349   1.377   1.361   1.238   1.284   1.235   1.137   1.188   1.094
201   K        -0.786  -0.798  -0.813  -0.653  -0.668  -0.686  -0.617  -0.628  -0.626
202   E        -0.786  -0.818  -0.824  -0.838  -0.893  -0.930  -0.617  -0.648  -0.637
203   F         0.361   0.332   0.202   0.563   0.517   0.292   0.327   0.285   0.097
204   I         1.014   0.997   0.835   1.090   1.069   0.855   1.002   0.972   0.693
205   H        -0.452  -0.421  -0.444  -0.415  -0.372  -0.403  -0.482  -0.449  -0.455
206   E        -0.578  -0.600  -0.528  -0.581  -0.615  -0.507  -0.617  -0.633  -0.546
207   V        -0.117  -0.128  -0.073  -0.186  -0.214  -0.124  -0.347  -0.357  -0.289
208   I         0.010  -0.009  -0.001  -0.290  -0.310  -0.286  -0.212  -0.230  -0.209
209   G        -0.942  -0.956  -0.916  -0.853  -0.900  -0.824  -0.769  -0.780  -0.722
210   D        -1.325  -1.317  -1.252  -1.124  -1.091  -1.017  -0.945  -0.937  -0.857
211   R        -0.415  -0.392  -0.440  -0.170  -0.140  -0.239  -0.416  -0.391  -0.439
212   R        -0.786  -0.780  -0.820  -0.614  -0.611  -0.684  -0.617  -0.610  -0.633
213   L        -0.913  -0.927  -0.881  -1.030  -1.038  -0.968  -0.752  -0.761  -0.696
214   K        -1.248  -1.264  -1.204  -1.223  -1.264  -1.159  -0.887  -0.898  -0.821
215   N        -1.248  -1.238  -1.208  -1.104  -1.085  -1.036  -0.887  -0.877  -0.824
216   S        -0.786  -0.763  -0.810  -0.688  -0.649  -0.735  -0.617  -0.592  -0.623
217   H        -0.452  -0.412  -0.449  -0.475  -0.431  -0.458  -0.482  -0.443  -0.463
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   I         1.014   0.958   0.813   1.029   0.955   0.728   1.002   0.912   0.657
222   F        -0.913  -0.925  -0.877  -0.613  -0.617  -0.546  -0.752  -0.760  -0.692
223   C        -0.117  -0.112  -0.094  -0.019  -0.026  -0.000  -0.347  -0.346  -0.313
224   N         2.436   2.444   2.535   2.549   2.566   2.703   2.756   2.766   2.907
225   D         0.092   0.121   0.040  -0.031   0.010  -0.118  -0.077  -0.039  -0.144
226   L         0.361   0.305   0.162   0.330   0.246   0.025   0.327   0.249   0.042
227   K        -0.786  -0.763  -0.810  -0.849  -0.804  -0.913  -0.617  -0.592  -0.623
228   K        -0.452  -0.448  -0.463  -0.295  -0.282  -0.298  -0.482  -0.479  -0.476
229   V        -0.452  -0.465  -0.446  -0.366  -0.378  -0.332  -0.482  -0.491  -0.459
230   S        -0.913  -0.937  -0.877  -0.972  -1.007  -0.916  -0.752  -0.769  -0.692
231   D         0.010  -0.000   0.002  -0.174  -0.185  -0.186  -0.212  -0.220  -0.204
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   Q        -0.942  -0.911  -0.897  -0.739  -0.705  -0.661  -0.769  -0.739  -0.705
240   S        -0.786  -0.791  -0.799  -0.688  -0.701  -0.729  -0.617  -0.622  -0.612
241   Y        -0.452  -0.466  -0.477  -0.275  -0.293  -0.312  -0.482  -0.496  -0.492
242   N         0.092   0.050   0.039   0.118   0.061   0.033  -0.077  -0.125  -0.145
243   G         2.436   2.444   2.535   2.518   2.527   2.672   2.756   2.766   2.907
244   E        -0.913  -0.914  -0.887  -0.977  -0.968  -0.927  -0.752  -0.750  -0.700
245   F        -0.243  -0.277  -0.368  -0.010  -0.069  -0.229  -0.212  -0.254  -0.357
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   D        -0.032  -0.041  -0.023  -0.187  -0.200  -0.177  -0.240  -0.253  -0.225
250   C        -0.559  -0.536  -0.522  -0.586  -0.559  -0.512  -0.592  -0.570  -0.535
251   R         0.206   0.242   0.099   0.298   0.347   0.136   0.113   0.159  -0.044
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   L         0.092   0.094   0.040  -0.063  -0.046  -0.142  -0.077  -0.072  -0.144
256   L         0.345   0.337   0.407   0.160   0.152   0.270  -0.077  -0.089  -0.005
257   T         1.014   1.023   0.839   1.233   1.244   1.010   1.002   1.013   0.700
258   G         0.553   0.526   0.549   0.411   0.372   0.416   0.192   0.158   0.185
259   S        -1.248  -1.267  -1.220  -1.184  -1.210  -1.147  -0.887  -0.900  -0.833
260   D         2.436   2.444   2.535   2.405   2.416   2.557   2.756   2.766   2.907
261   K         2.436   2.444   2.535   2.374   2.389   2.526   2.756   2.766   2.907
262   V         0.092   0.100   0.040  -0.101  -0.086  -0.178  -0.077  -0.065  -0.144
263   K        -1.248  -1.211  -1.202  -1.165  -1.105  -1.097  -0.887  -0.855  -0.819
264   I        -0.786  -0.827  -0.821  -0.662  -0.711  -0.705  -0.617  -0.657  -0.634
265   L         0.427   0.422   0.460   0.107   0.098   0.152   0.058   0.047   0.079
266   G        -0.786  -0.766  -0.801  -0.673  -0.646  -0.692  -0.617  -0.596  -0.614
267   E        -0.452  -0.456  -0.477  -0.427  -0.439  -0.451  -0.482  -0.488  -0.491
268   I         0.361   0.340   0.183   0.421   0.400   0.154   0.327   0.296   0.071
269   L        -0.913  -0.925  -0.871  -0.890  -0.896  -0.806  -0.752  -0.759  -0.688
270   D        -1.248  -1.247  -1.211  -1.313  -1.315  -1.271  -0.887  -0.884  -0.826
271   K        -0.913  -0.924  -0.885  -1.004  -1.025  -0.954  -0.752  -0.758  -0.699
272   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
276   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   E         0.481   0.478   0.503   0.265   0.252   0.298   0.117   0.109   0.132
280   G        -0.134  -0.114  -0.088  -0.225  -0.201  -0.161  -0.362  -0.340  -0.302
281   N        -0.942  -0.917  -0.894  -0.919  -0.877  -0.847  -0.769  -0.744  -0.702
282   S        -1.248  -1.235  -1.203  -1.007  -0.992  -0.930  -0.887  -0.875  -0.820
283   C        -0.913  -0.919  -0.883  -0.814  -0.831  -0.751  -0.752  -0.756  -0.697
284   S         0.010   0.012  -0.005  -0.234  -0.224  -0.253  -0.212  -0.208  -0.212
285   Y        -0.913  -0.881  -0.875  -1.027  -0.983  -0.972  -0.752  -0.725  -0.691
286   W        -0.452  -0.427  -0.450  -0.195  -0.174  -0.168  -0.482  -0.450  -0.460
287   Y         2.436   2.444   2.535   2.614   2.625   2.769   2.756   2.766   2.907
288   I         1.014   0.974   0.816   1.109   1.064   0.857   1.002   0.937   0.661
289   G         2.436   2.444   2.535   2.518   2.527   2.672   2.756   2.766   2.907
290   D         2.436   2.444   2.535   2.405   2.416   2.557   2.756   2.766   2.907
291   S         2.436   2.444   2.535   2.430   2.442   2.583   2.756   2.766   2.907
292   E        -0.913  -0.924  -0.885  -0.790  -0.802  -0.722  -0.752  -0.758  -0.699
293   T         1.708   1.679   1.602   1.838   1.801   1.706   1.812   1.758   1.582
294   D         2.436   2.444   2.535   2.405   2.416   2.557   2.756   2.766   2.907
295   L         1.014   1.023   0.839   0.971   0.984   0.722   1.002   1.013   0.700
296   L        -0.243  -0.315  -0.372  -0.206  -0.315  -0.387  -0.212  -0.299  -0.361
297   S        -0.117  -0.079  -0.074   0.008   0.075   0.077  -0.347  -0.300  -0.289
298   I         1.157   1.174   1.236   0.688   0.720   0.795   0.732   0.763   0.824
299   L         1.014   1.015   0.835   0.975   0.976   0.721   1.002   1.000   0.694
300   H        -1.248  -1.267  -1.220  -0.960  -0.996  -0.944  -0.887  -0.900  -0.833
301   P        -0.913  -0.885  -0.873  -0.739  -0.714  -0.673  -0.752  -0.728  -0.689
302   S         0.092   0.083   0.045   0.012   0.012  -0.050  -0.077  -0.078  -0.131
303   T         0.092   0.087   0.056  -0.004  -0.008  -0.056  -0.077  -0.083  -0.125
304   N        -0.452  -0.452  -0.457  -0.365  -0.364  -0.368  -0.482  -0.476  -0.467
305   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   L         0.553   0.585   0.570   0.220   0.276   0.273   0.192   0.239   0.218
308   L        -0.032  -0.053  -0.039  -0.251  -0.287  -0.266  -0.240  -0.260  -0.242
309   I         0.589   0.554   0.562   0.439   0.393   0.401   0.289   0.234   0.223
310   N        -1.325  -1.317  -1.252  -1.289  -1.273  -1.185  -0.945  -0.937  -0.857
311   P        -0.559  -0.550  -0.530  -0.489  -0.480  -0.464  -0.592  -0.581  -0.543
312   Q        -0.415  -0.383  -0.425  -0.403  -0.358  -0.424  -0.416  -0.379  -0.422
313   E        -0.942  -0.956  -0.916  -0.855  -0.879  -0.804  -0.769  -0.780  -0.722
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   N        -0.452  -0.447  -0.454  -0.570  -0.560  -0.582  -0.482  -0.471  -0.464
321   P        -0.913  -0.888  -0.872  -0.896  -0.881  -0.834  -0.752  -0.729  -0.689
322   S         0.010  -0.029  -0.009  -0.201  -0.254  -0.218  -0.212  -0.251  -0.216
323   K        -0.913  -0.910  -0.886  -0.984  -0.964  -0.954  -0.752  -0.747  -0.699
324   F         0.553   0.560   0.558   0.347   0.336   0.346   0.192   0.193   0.197
325   I         0.092   0.121   0.056  -0.105  -0.056  -0.179  -0.077  -0.042  -0.122
326   K         0.361   0.282   0.174   0.481   0.377   0.223   0.327   0.217   0.059
327   I        -0.243  -0.210  -0.331  -0.288  -0.239  -0.432  -0.212  -0.173  -0.312
328   T        -0.786  -0.761  -0.804  -0.554  -0.521  -0.585  -0.617  -0.591  -0.617
329   E        -0.578  -0.587  -0.534  -0.773  -0.782  -0.700  -0.617  -0.622  -0.550
330   K        -0.134  -0.107  -0.090  -0.402  -0.364  -0.335  -0.362  -0.333  -0.305
331   I         1.206   1.233   1.258   0.971   1.019   1.024   0.837   0.888   0.872
332   I        -0.134  -0.090  -0.090  -0.326  -0.243  -0.274  -0.362  -0.315  -0.304
333   G        -0.139  -0.176  -0.117  -0.122  -0.174  -0.090  -0.353  -0.401  -0.330
334   I         0.397   0.391   0.457  -0.007  -0.020   0.071  -0.007  -0.016   0.064
335   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   F        -0.559  -0.513  -0.516  -0.400  -0.347  -0.323  -0.592  -0.549  -0.530
354   C        -0.942  -0.916  -0.894  -1.000  -0.967  -0.932  -0.769  -0.743  -0.702
355   E        -0.415  -0.387  -0.437  -0.234  -0.193  -0.285  -0.416  -0.385  -0.435
356   K        -0.415  -0.467  -0.456  -0.482  -0.567  -0.565  -0.416  -0.475  -0.457
357   E         0.206   0.227   0.116   0.234   0.265   0.095   0.113   0.140  -0.021
358   G         0.481   0.507   0.520   0.271   0.309   0.333   0.117   0.153   0.160
359   G        -1.027  -1.020  -0.952  -1.022  -1.014  -0.914  -0.842  -0.835  -0.752
360   K         0.589   0.615   0.591   0.472   0.512   0.477   0.289   0.326   0.272
361   G        -0.580  -0.579  -0.532  -0.725  -0.730  -0.675  -0.602  -0.600  -0.539
362   A        -0.415  -0.383  -0.425  -0.550  -0.506  -0.578  -0.416  -0.379  -0.422
363   Y         0.206   0.205   0.105   0.413   0.411   0.231   0.113   0.109  -0.036
364   L        -0.559  -0.579  -0.534  -0.544  -0.559  -0.483  -0.592  -0.609  -0.547
365   V        -0.032  -0.060  -0.033   0.040  -0.002   0.059  -0.240  -0.275  -0.239
366   K        -0.559  -0.589  -0.541  -0.657  -0.697  -0.627  -0.592  -0.619  -0.553
367   S        -0.032   0.015  -0.018  -0.186  -0.107  -0.157  -0.240  -0.179  -0.214
368   W         1.643   1.598   1.548   1.991   1.928   1.862   1.699   1.613   1.476
369   D        -0.942  -0.923  -0.890  -0.852  -0.813  -0.770  -0.769  -0.749  -0.699
370   S        -0.942  -0.911  -0.897  -0.936  -0.894  -0.868  -0.769  -0.739  -0.705
371   L         0.206   0.227   0.125   0.238   0.265   0.085   0.113   0.140  -0.009
372   K        -0.559  -0.562  -0.526  -0.641  -0.639  -0.591  -0.592  -0.594  -0.539
373   D        -0.580  -0.594  -0.551  -0.607  -0.628  -0.577  -0.602  -0.616  -0.560
374   L        -0.134  -0.164  -0.087  -0.463  -0.495  -0.387  -0.362  -0.394  -0.301
375   I        -0.134  -0.164  -0.088  -0.518  -0.556  -0.451  -0.362  -0.394  -0.302
376   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
377   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
379   T        -0.580  -0.587  -0.533  -0.666  -0.684  -0.615  -0.602  -0.609  -0.541
380   K         0.092   0.075   0.030  -0.022  -0.049  -0.107  -0.077  -0.103  -0.157
381   M        -1.248  -1.245  -1.206  -0.865  -0.866  -0.781  -0.887  -0.883  -0.822
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25616
Output conservation file - output/P25616
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
