1     M         2.262   2.361   2.590   2.601   2.756   3.132   2.605   2.773   3.215
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.592  -1.460  -1.310  -1.430  -1.256  -1.067  -1.171  -1.058  -0.897
11    -        -0.405  -0.269  -0.421  -0.256  -0.090  -0.357  -0.399  -0.257  -0.448
12    -        -0.758  -0.742  -0.579  -0.699  -0.723  -0.480  -0.828  -0.800  -0.626
13    K         0.065  -0.127  -0.492   0.425   0.212  -0.280   0.300   0.064  -0.358
14    A         2.262   2.361   2.590   2.182   2.325   2.699   2.605   2.773   3.215
15    V         0.005  -0.021  -0.056  -0.168  -0.248  -0.195  -0.203  -0.267  -0.265
16    V         0.751   0.899   0.832   0.474   0.665   0.498   0.486   0.681   0.469
17    I        -0.467  -0.394  -0.432  -0.750  -0.672  -0.703  -0.574  -0.490  -0.492
18    -        -0.717  -0.807  -0.579  -0.826  -0.983  -0.682  -0.800  -0.854  -0.627
19    -         0.182   0.455   0.267  -0.000   0.372   0.103  -0.141   0.204  -0.061
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    E        -1.084  -1.040  -0.978  -0.841  -0.766  -0.687  -0.892  -0.836  -0.741
24    D        -0.526  -0.421  -0.437  -0.610  -0.466  -0.447  -0.627  -0.518  -0.500
25    G        -1.084  -1.055  -0.842  -1.079  -1.025  -0.731  -0.998  -0.942  -0.733
26    K        -0.467  -0.522  -0.441  -0.622  -0.678  -0.557  -0.574  -0.599  -0.500
27    A        -0.229  -0.301  -0.121  -0.601  -0.672  -0.429  -0.521  -0.543  -0.345
28    V        -1.032  -1.135  -1.021  -0.919  -1.093  -0.918  -0.865  -0.926  -0.782
29    V         0.373   0.413   0.631  -0.206  -0.178   0.128  -0.150  -0.125   0.128
30    K        -0.001  -0.204  -0.332   0.122  -0.162  -0.416   0.062  -0.194  -0.359
31    E         0.189   0.208   0.060   0.242   0.220   0.090   0.009  -0.014  -0.129
32    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    V        -0.337  -0.443  -0.405  -0.550  -0.694  -0.614  -0.468  -0.543  -0.464
34    P        -0.001  -0.012  -0.296   0.308   0.264  -0.203   0.062   0.027  -0.315
35    I        -0.810  -0.814  -0.754  -0.979  -1.010  -0.908  -0.786  -0.767  -0.665
36    P         0.907   0.870   0.563   1.212   1.148   0.741   0.989   0.911   0.417
37    E        -0.504  -0.480  -0.274  -0.833  -0.807  -0.542  -0.733  -0.701  -0.488
38    L        -0.639  -0.820  -0.773  -0.671  -0.962  -0.979  -0.574  -0.748  -0.677
39    E        -1.462  -1.294  -1.268  -1.379  -1.202  -1.145  -1.104  -0.986  -0.876
40    E         0.377   0.298   0.312   0.384   0.265   0.238   0.168   0.046   0.001
41    G        -0.477  -0.507  -0.434  -0.639  -0.650  -0.540  -0.627  -0.615  -0.507
42    F        -0.748  -0.714  -0.745  -0.480  -0.479  -0.481  -0.706  -0.679  -0.657
43    V         0.521   0.464   0.412   0.328   0.237   0.168   0.274   0.179   0.113
44    L         1.880   1.926   1.835   1.898   1.984   1.909   2.154   2.232   2.033
45    I         0.788   0.752   0.859   0.441   0.384   0.516   0.406   0.349   0.462
46    K         1.641   1.528   1.584   1.651   1.517   1.587   1.757   1.500   1.472
47    T         0.150   0.249   0.270  -0.280  -0.171  -0.088  -0.229  -0.119  -0.078
48    L        -1.051  -0.943  -0.799  -1.269  -1.149  -0.941  -0.971  -0.874  -0.702
49    A         0.414   0.049  -0.206   0.712   0.282  -0.027   0.618   0.157  -0.186
50    V        -1.077  -0.952  -1.003  -1.129  -1.052  -1.010  -0.918  -0.816  -0.769
51    A         1.880   1.805   1.828   1.873   1.810   1.881   2.154   2.028   2.018
52    G        -0.999  -1.015  -0.837  -1.187  -1.093  -0.889  -0.945  -0.915  -0.733
53    N         2.262   2.361   2.590   2.395   2.564   2.920   2.605   2.773   3.215
54    P         1.880   1.927   1.834   2.119   2.201   2.173   2.154   2.234   2.030
55    T         0.521   0.331   0.406   0.417   0.147   0.206   0.274   0.022   0.096
56    D         2.262   2.361   2.590   2.303   2.459   2.825   2.605   2.773   3.215
57    W         1.096   1.029   0.952   1.417   1.291   1.172   1.042   0.884   0.696
58    A         0.770   0.729   0.256   0.990   0.982   0.339   0.963   0.913   0.229
59    H         0.751   0.613   0.712   0.844   0.541   0.616   0.486   0.196   0.264
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    I        -0.333  -0.529  -0.665  -0.103  -0.395  -0.615  -0.203  -0.448  -0.570
62    D        -0.554  -0.628  -0.669  -0.649  -0.784  -0.845  -0.521  -0.602  -0.590
63    Y        -1.547  -1.459  -1.400  -1.209  -1.077  -1.028  -1.104  -1.021  -0.898
64    K        -0.639  -0.671  -0.678  -0.500  -0.520  -0.540  -0.574  -0.575  -0.583
65    V        -1.410  -1.447  -1.273  -1.136  -1.228  -1.015  -1.077  -1.065  -0.879
66    G        -0.416  -0.545  -0.456  -0.542  -0.730  -0.637  -0.494  -0.597  -0.505
67    P        -0.432  -0.283  -0.381  -0.537  -0.343  -0.393  -0.574  -0.422  -0.447
68    Q        -0.706  -0.696  -0.554  -0.739  -0.758  -0.589  -0.786  -0.759  -0.609
69    G         1.880   1.805   1.828   1.924   1.864   1.956   2.154   2.028   2.018
70    S        -0.947  -1.116  -1.003  -0.976  -1.215  -1.093  -0.812  -0.910  -0.767
71    I         0.521   0.426   0.451   0.350   0.317   0.324   0.274   0.207   0.192
72    L        -0.989  -1.094  -0.977  -1.072  -1.224  -1.157  -0.786  -0.850  -0.737
73    G         2.262   2.361   2.590   2.220   2.360   2.739   2.605   2.773   3.215
74    C        -0.474  -0.691  -0.649  -0.159  -0.353  -0.289  -0.494  -0.636  -0.562
75    D         1.880   1.927   1.834   2.004   2.102   2.041   2.154   2.234   2.030
76    A        -0.313  -0.347  -0.247  -0.598  -0.696  -0.595  -0.494  -0.568  -0.458
77    A         0.326   0.195   0.291   0.113  -0.126  -0.026   0.035  -0.150  -0.050
78    G         1.880   1.851   1.828   1.910   1.899   1.914   2.154   2.109   2.018
79    Q        -0.106   0.008  -0.059  -0.219  -0.048  -0.192  -0.282  -0.138  -0.250
80    I         1.319   1.469   1.497   1.052   1.276   1.254   1.121   1.377   1.264
81    V        -0.133  -0.083  -0.301  -0.110  -0.045  -0.302  -0.229  -0.170  -0.351
82    K        -0.133  -0.178  -0.330  -0.098  -0.193  -0.360  -0.229  -0.283  -0.384
83    L         0.599   0.640   0.722   0.232   0.246   0.302   0.247   0.263   0.288
84    G         1.880   1.926   1.835   1.910   1.988   1.925   2.154   2.232   2.033
85    P        -0.306  -0.291  -0.359  -0.280  -0.233  -0.326  -0.415  -0.374  -0.424
86    A        -1.214  -1.184  -1.052  -1.128  -1.081  -0.927  -0.998  -0.957  -0.801
87    V         1.641   1.769   1.623   1.547   1.718   1.485   1.757   1.965   1.565
88    D        -1.129  -1.151  -1.049  -1.065  -1.043  -0.928  -0.945  -0.938  -0.799
89    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    D        -1.032  -1.049  -0.821  -1.108  -1.075  -0.797  -0.971  -0.940  -0.722
92    F        -0.138  -0.305  -0.573   0.360   0.110  -0.311   0.035  -0.176  -0.460
93    S        -0.466  -0.477  -0.645  -0.383  -0.422  -0.650  -0.388  -0.420  -0.548
94    I        -0.148  -0.203  -0.086  -0.526  -0.559  -0.393  -0.415  -0.432  -0.295
95    G         2.262   2.361   2.590   2.220   2.360   2.739   2.605   2.773   3.215
96    D         0.339   0.210   0.047   0.541   0.364   0.081   0.353   0.175  -0.080
97    Y        -1.377  -1.084  -1.197  -1.258  -0.823  -1.024  -1.051  -0.825  -0.827
98    I         0.614   0.659   0.461   0.446   0.448   0.188   0.459   0.460   0.198
99    Y         0.268   0.281   0.292   0.153   0.094   0.148  -0.018  -0.057  -0.041
100   G         0.322   0.398   0.624  -0.218  -0.142   0.178  -0.229  -0.146   0.117
101   F         0.551   0.577   0.178   0.977   1.042   0.480   0.645   0.689   0.098
102   I        -0.607  -0.594  -0.467  -0.860  -0.861  -0.628  -0.721  -0.695  -0.533
103   H        -1.066  -1.145  -1.189  -0.563  -0.663  -0.790  -0.751  -0.797  -0.806
104   G         2.262   2.361   2.590   2.241   2.390   2.761   2.605   2.773   3.215
105   S        -0.303  -0.517  -0.464  -0.152  -0.444  -0.426  -0.345  -0.570  -0.519
106   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   R        -1.925  -1.864  -1.658  -1.617  -1.516  -1.226  -1.262  -1.190  -0.993
109   F        -1.084  -1.181  -1.029  -0.957  -1.114  -0.906  -0.892  -0.945  -0.785
110   P        -0.639  -0.752  -0.739  -0.470  -0.688  -0.716  -0.574  -0.686  -0.650
111   S        -1.403  -1.368  -1.262  -1.303  -1.318  -1.127  -1.051  -1.019  -0.871
112   N        -0.526  -0.487  -0.450  -0.405  -0.332  -0.269  -0.627  -0.584  -0.510
113   G         1.880   1.851   1.828   1.910   1.899   1.914   2.154   2.109   2.018
114   A         1.096   1.034   0.935   1.028   0.881   0.743   1.042   0.847   0.648
115   F         1.641   1.528   1.584   1.908   1.769   1.853   1.757   1.500   1.472
116   A         0.457   0.542   0.437   0.218   0.342   0.269   0.141   0.244   0.143
117   E         0.614   0.649   0.470   0.712   0.757   0.527   0.459   0.489   0.216
118   Y         1.641   1.617   1.627   1.908   1.894   1.925   1.757   1.678   1.574
119   S        -0.365  -0.403  -0.410  -0.592  -0.707  -0.655  -0.468  -0.518  -0.474
120   A        -0.432  -0.411  -0.389  -0.726  -0.695  -0.634  -0.574  -0.536  -0.464
121   I         0.268   0.355   0.293  -0.055   0.045  -0.114  -0.018   0.081  -0.041
122   S        -0.885  -0.909  -0.918  -0.731  -0.754  -0.779  -0.733  -0.728  -0.696
123   T        -0.587  -0.699  -0.698  -0.430  -0.643  -0.629  -0.547  -0.666  -0.613
124   V        -1.736  -1.730  -1.637  -1.465  -1.480  -1.424  -1.157  -1.124  -0.980
125   V        -0.607  -0.611  -0.499  -0.921  -0.900  -0.762  -0.733  -0.710  -0.564
126   A        -0.450  -0.448  -0.484  -0.464  -0.514  -0.568  -0.521  -0.548  -0.541
127   Y         0.005  -0.128  -0.109  -0.028  -0.192  -0.151  -0.203  -0.364  -0.319
128   K        -0.001  -0.243  -0.344   0.162  -0.157  -0.338   0.062  -0.240  -0.375
129   S        -0.550  -0.664  -0.729  -0.303  -0.588  -0.687  -0.484  -0.634  -0.642
130   P         0.216   0.428   0.332   0.091   0.393   0.316  -0.157   0.103   0.007
131   N        -0.748  -0.605  -0.688  -0.711  -0.513  -0.630  -0.706  -0.536  -0.599
132   E        -0.830  -0.698  -0.696  -0.835  -0.633  -0.623  -0.812  -0.682  -0.621
133   L        -0.862  -0.859  -0.768  -1.017  -1.063  -0.899  -0.812  -0.807  -0.678
134   K        -1.474  -1.297  -1.284  -1.446  -1.195  -1.288  -1.102  -0.962  -0.883
135   F        -1.095  -1.083  -1.030  -0.769  -0.733  -0.689  -0.899  -0.869  -0.779
136   L         0.593   0.715   0.382   0.679   0.845   0.320   0.523   0.675   0.122
137   G        -0.951  -0.815  -0.807  -1.059  -0.884  -0.827  -0.899  -0.774  -0.705
138   E        -0.372  -0.250  -0.192  -0.644  -0.483  -0.399  -0.594  -0.458  -0.401
139   D        -0.786  -0.520  -0.772  -0.953  -0.600  -1.016  -0.747  -0.508  -0.672
140   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
142   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   P        -1.213  -1.107  -1.072  -1.146  -0.989  -0.938  -1.001  -0.903  -0.814
146   A         0.008   0.077   0.204  -0.370  -0.295  -0.115  -0.391  -0.325  -0.156
147   G        -0.073   0.153  -0.092  -0.225   0.127  -0.220  -0.290   0.009  -0.275
148   P        -1.403  -1.239  -1.251  -1.215  -0.969  -1.031  -1.051  -0.902  -0.859
149   V         1.163   1.173   1.370   0.786   0.726   0.992   0.777   0.707   0.945
150   R        -0.254  -0.173  -0.153  -0.432  -0.309  -0.218  -0.493  -0.396  -0.359
151   S        -0.306  -0.299  -0.330  -0.274  -0.215  -0.239  -0.415  -0.375  -0.384
152   L         0.045   0.061  -0.044   0.273   0.265   0.112  -0.097  -0.102  -0.237
153   E         1.134   0.947   0.666   1.443   1.244   0.859   1.333   1.066   0.597
154   G        -0.328  -0.471  -0.444  -0.316  -0.556  -0.531  -0.362  -0.540  -0.500
155   A         1.504   1.655   1.238   1.560   1.755   1.263   1.731   1.961   1.262
156   A         1.880   1.862   1.828   1.878   1.888   1.895   2.154   2.126   2.019
157   T         0.457   0.430   0.417   0.335   0.274   0.351   0.141   0.076   0.105
158   I        -0.477  -0.266  -0.359  -0.731  -0.402  -0.442  -0.627  -0.381  -0.430
159   P         0.105   0.231   0.293  -0.035   0.222   0.266  -0.282  -0.061  -0.035
160   V         0.135   0.258   0.069  -0.074   0.060  -0.070  -0.097   0.035  -0.121
161   S         0.326   0.202   0.286   0.103  -0.090   0.002   0.035  -0.122  -0.047
162   L         0.551   0.232   0.072   0.771   0.379   0.176   0.645   0.204  -0.053
163   T        -0.947  -0.930  -0.928  -1.000  -0.921  -0.955  -0.812  -0.770  -0.710
164   T         2.262   2.361   2.590   2.316   2.477   2.837   2.605   2.773   3.215
165   A         0.594   0.880   0.814   0.142   0.615   0.476   0.168   0.625   0.454
166   G         0.268   0.169   0.268  -0.026  -0.248  -0.135  -0.018  -0.171  -0.077
167   L        -0.992  -0.836  -0.760  -1.153  -0.968  -0.794  -0.918  -0.786  -0.668
168   V         0.515   0.549   0.706   0.174   0.141   0.347   0.088   0.070   0.248
169   L         1.028   1.153   1.371   0.687   0.855   1.180   0.459   0.659   0.947
170   T        -1.325  -1.259  -1.104  -1.081  -0.961  -0.747  -1.077  -1.017  -0.838
171   Y        -0.380  -0.525  -0.493  -0.052  -0.299  -0.330  -0.388  -0.557  -0.541
172   N        -1.221  -1.248  -1.039  -1.033  -1.022  -0.758  -1.024  -1.001  -0.798
173   L         1.134   1.143   0.706   1.318   1.360   0.850   1.333   1.351   0.661
174   G        -0.039   0.074  -0.029  -0.134   0.031  -0.057  -0.282  -0.128  -0.228
175   L         0.717   0.829   0.872   0.310   0.491   0.598   0.247   0.412   0.490
176   N        -1.188  -1.064  -0.999  -1.310  -1.142  -1.065  -0.998  -0.893  -0.768
177   L        -0.947  -0.890  -0.933  -1.036  -0.882  -0.929  -0.812  -0.715  -0.701
178   K        -1.084  -1.025  -0.837  -1.052  -0.945  -0.698  -0.998  -0.919  -0.730
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   W         0.226   0.096   0.225   0.166   0.049   0.244  -0.111  -0.270  -0.133
182   E        -1.046  -1.190  -0.986  -0.910  -1.131  -0.849  -0.882  -0.950  -0.751
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   P        -0.457  -0.180  -0.585  -0.196   0.134  -0.415  -0.379  -0.104  -0.490
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   S        -0.229  -0.272  -0.122  -0.492  -0.508  -0.299  -0.521  -0.525  -0.345
201   T        -0.940  -0.958  -0.802  -1.082  -1.085  -0.885  -0.892  -0.871  -0.701
202   P         0.193   0.139   0.296  -0.033  -0.125   0.082  -0.150  -0.215  -0.047
203   Q         0.064   0.041   0.012   0.346   0.342   0.261  -0.018  -0.039  -0.121
204   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   P        -0.480  -0.486  -0.470  -0.335  -0.328  -0.329  -0.554  -0.536  -0.514
208   I         0.751   0.645   0.729   0.532   0.302   0.337   0.486   0.262   0.296
209   L         1.880   1.805   1.828   1.898   1.836   1.897   2.154   2.028   2.018
210   L         0.325   0.360   0.300   0.224   0.208   0.053   0.141   0.133  -0.003
211   W         1.880   1.805   1.828   2.292   2.248   2.338   2.154   2.028   2.018
212   G         1.641   1.695   1.596   1.633   1.709   1.542   1.757   1.828   1.502
213   G         1.880   1.805   1.828   1.910   1.841   1.914   2.154   2.028   2.018
214   A         0.528   0.389   0.333   0.481   0.220   0.138   0.406   0.125   0.039
215   T         1.319   1.254   1.407   1.233   1.080   1.247   1.121   0.898   1.039
216   A         0.216   0.254   0.227  -0.016  -0.018  -0.092  -0.044  -0.054  -0.112
217   V         1.039   1.216   1.412   0.546   0.835   1.118   0.486   0.809   1.053
218   G         2.262   2.361   2.590   2.220   2.360   2.739   2.605   2.773   3.215
219   Q        -0.415  -0.485  -0.458  -0.372  -0.414  -0.346  -0.547  -0.609  -0.524
220   S        -0.133  -0.072  -0.313  -0.104  -0.034  -0.281  -0.229  -0.212  -0.375
221   L         0.614   0.523   0.464   0.476   0.385   0.265   0.459   0.368   0.237
222   I         1.271   1.090   1.004   1.324   1.087   0.898   1.360   1.042   0.804
223   Q         2.262   2.361   2.590   2.486   2.637   3.013   2.605   2.773   3.215
224   L         0.741   0.843   0.859   0.287   0.390   0.495   0.300   0.394   0.460
225   A         2.262   2.361   2.590   2.182   2.325   2.699   2.605   2.773   3.215
226   N         1.134   1.012   0.682   1.320   1.227   0.824   1.333   1.156   0.622
227   K         0.410   0.290   0.312   0.311   0.184   0.187   0.194   0.041  -0.002
228   L        -0.810  -0.899  -0.746  -1.128  -1.272  -1.064  -0.786  -0.835  -0.663
229   N         0.673   0.627   0.730   0.777   0.650   0.774   0.372   0.218   0.296
230   G         0.521   0.595   0.511   0.402   0.579   0.456   0.274   0.463   0.312
231   F         0.083   0.054   0.179  -0.017  -0.073   0.138  -0.229  -0.317  -0.187
232   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   K        -0.333  -0.348  -0.578  -0.060  -0.047  -0.354  -0.203  -0.206  -0.470
234   I         0.962   0.929   0.957   0.750   0.729   0.737   0.777   0.750   0.706
235   I         1.271   1.337   1.102   1.320   1.442   1.078   1.360   1.467   1.000
236   V         0.688   0.625   0.429   0.831   0.788   0.394   0.671   0.577   0.196
237   V         0.861   0.809   0.890   0.684   0.642   0.703   0.565   0.505   0.552
238   A         1.504   1.365   1.195   1.595   1.474   1.304   1.731   1.520   1.184
239   S         1.504   1.377   1.203   1.687   1.579   1.370   1.731   1.535   1.199
240   R        -0.328  -0.374  -0.399  -0.116  -0.158  -0.213  -0.362  -0.400  -0.439
241   K        -0.333  -0.540  -0.657  -0.125  -0.437  -0.622  -0.203  -0.447  -0.559
242   H         0.108  -0.030   0.006   0.217   0.099   0.168  -0.150  -0.252  -0.187
243   E        -0.554  -0.794  -0.745  -0.264  -0.628  -0.594  -0.521  -0.729  -0.650
244   K        -0.641  -0.483  -0.469  -0.860  -0.655  -0.615  -0.759  -0.615  -0.540
245   L        -1.111  -1.114  -1.017  -0.837  -0.819  -0.631  -0.945  -0.916  -0.778
246   L         1.641   1.528   1.584   1.615   1.448   1.489   1.757   1.500   1.472
247   K         0.528   0.392   0.352   0.529   0.350   0.227   0.406   0.213   0.064
248   E        -1.084  -0.999  -0.969  -1.005  -0.894  -0.884  -0.892  -0.797  -0.735
249   Y         1.319   1.444   1.533   1.177   1.363   1.475   1.121   1.323   1.352
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   G         1.880   1.805   1.828   1.912   1.845   1.918   2.154   2.028   2.018
255   A         1.880   1.805   1.828   1.873   1.810   1.881   2.154   2.028   2.018
256   D         1.504   1.437   1.203   1.695   1.658   1.372   1.731   1.631   1.199
257   Q        -1.736  -1.645  -1.486  -1.524  -1.475  -1.198  -1.209  -1.124  -0.948
258   L         0.658   0.653   0.742   0.326   0.298   0.385   0.300   0.275   0.320
259   F         0.079  -0.036  -0.006   0.213   0.121   0.101  -0.071  -0.156  -0.160
260   D         1.134   1.016   0.668   1.410   1.320   0.883   1.333   1.168   0.600
261   Y         2.262   2.361   2.590   2.459   2.610   2.985   2.605   2.773   3.215
262   H        -0.328  -0.277  -0.401   0.012   0.115  -0.125  -0.362  -0.296  -0.443
263   D         1.641   1.535   1.569   1.724   1.582   1.597   1.757   1.513   1.437
264   I        -0.810  -0.861  -0.739  -0.964  -1.040  -0.876  -0.786  -0.798  -0.650
265   D         0.050   0.136  -0.213   0.299   0.413  -0.049   0.088   0.181  -0.232
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   V         1.641   1.851   1.717   1.554   1.830   1.668   1.757   2.108   1.778
269   V         1.072   1.171   1.362   0.564   0.701   0.963   0.565   0.703   0.925
270   E         0.410   0.581   0.376   0.447   0.682   0.374   0.194   0.412   0.090
271   Q         0.005  -0.012  -0.007   0.058   0.078   0.035  -0.203  -0.181  -0.192
272   I         1.096   1.308   1.102   1.059   1.404   1.085   1.042   1.415   1.001
273   K         1.096   1.222   0.966   1.126   1.272   0.979   1.042   1.174   0.706
274   H        -0.328  -0.186  -0.355  -0.339  -0.084  -0.403  -0.362  -0.162  -0.394
275   K        -1.462  -1.383  -1.298  -1.711  -1.589  -1.507  -1.104  -1.025  -0.893
276   Y        -0.365  -0.471  -0.415  -0.305  -0.419  -0.365  -0.460  -0.533  -0.463
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
279   N        -0.639  -0.673  -0.713  -0.566  -0.590  -0.672  -0.574  -0.586  -0.615
280   N        -0.748  -0.742  -0.699  -0.534  -0.538  -0.455  -0.706  -0.691  -0.616
281   I         0.962   0.844   0.886   0.824   0.624   0.621   0.777   0.548   0.532
282   S        -1.221  -1.274  -1.210  -0.988  -1.059  -0.938  -0.918  -0.933  -0.831
283   Y        -0.467  -0.457  -0.427  -0.273  -0.223  -0.189  -0.574  -0.529  -0.478
284   L        -0.425  -0.391  -0.233  -0.914  -0.907  -0.713  -0.653  -0.613  -0.446
285   V         0.268   0.310   0.316   0.072   0.110   0.122  -0.018  -0.002  -0.011
286   D         2.262   2.361   2.590   2.303   2.459   2.825   2.605   2.773   3.215
287   C        -0.193  -0.126  -0.109  -0.277  -0.216  -0.085  -0.468  -0.399  -0.327
288   V         0.741   0.742   0.853   0.298   0.321   0.491   0.300   0.326   0.460
289   A         0.416   0.534   0.668  -0.007   0.151   0.289  -0.071   0.066   0.191
290   N        -0.663  -0.741  -0.686  -0.559  -0.661  -0.599  -0.653  -0.720  -0.614
291   Q        -1.410  -1.271  -1.211  -1.379  -1.218  -1.133  -1.077  -0.955  -0.842
292   N        -1.221  -1.208  -1.012  -1.145  -1.117  -0.848  -1.024  -0.971  -0.775
293   T         1.319   1.384   1.434   1.233   1.331   1.308   1.121   1.192   1.108
294   L        -0.466  -0.700  -0.708  -0.180  -0.522  -0.616  -0.388  -0.614  -0.608
295   Q        -0.001  -0.167  -0.313   0.417   0.188  -0.074   0.062  -0.147  -0.335
296   Q        -1.599  -1.555  -1.447  -1.464  -1.355  -1.274  -1.130  -1.063  -0.924
297   V        -0.467  -0.490  -0.456  -0.694  -0.728  -0.655  -0.574  -0.592  -0.515
298   Y         0.551   0.245   0.071   0.932   0.494   0.168   0.645   0.212  -0.055
299   K         0.135   0.012   0.006   0.016  -0.118  -0.102  -0.097  -0.221  -0.189
300   C        -0.007  -0.002  -0.089  -0.072  -0.110  -0.256  -0.123  -0.136  -0.276
301   A         0.521   0.343   0.410   0.422   0.191   0.266   0.274   0.051   0.112
302   A        -0.810  -0.639  -0.692  -0.992  -0.830  -0.824  -0.786  -0.659  -0.619
303   D        -0.433  -0.408  -0.185  -0.710  -0.616  -0.319  -0.691  -0.629  -0.402
304   K        -0.052  -0.264  -0.110  -0.128  -0.428  -0.270  -0.245  -0.471  -0.320
305   Q        -0.830  -0.764  -0.746  -0.871  -0.858  -0.753  -0.812  -0.762  -0.665
306   D        -1.084  -1.166  -1.026  -1.001  -1.170  -1.008  -0.892  -0.939  -0.785
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   A         1.101   1.162   1.361   0.614   0.652   0.939   0.634   0.680   0.920
313   T        -0.819  -0.784  -0.777  -0.669  -0.581  -0.612  -0.767  -0.708  -0.673
314   V         0.297   0.194   0.324  -0.072  -0.204  -0.023  -0.066  -0.164  -0.002
315   V         0.497   0.309   0.328   0.440   0.140   0.097   0.328   0.057   0.038
316   E        -1.077  -1.191  -1.035  -0.950  -1.066  -0.858  -0.918  -0.962  -0.791
317   L         0.188  -0.079  -0.066   0.209  -0.182  -0.226   0.115  -0.234  -0.250
318   T        -0.758  -0.797  -0.907  -0.741  -0.724  -0.912  -0.653  -0.650  -0.681
319   N        -1.358  -1.239  -1.206  -1.338  -1.190  -1.121  -1.051  -0.933  -0.834
320   L         0.410   0.358   0.316   0.279   0.142   0.109   0.194   0.087  -0.004
321   T        -0.974  -0.979  -0.828  -0.957  -0.909  -0.732  -0.918  -0.901  -0.727
322   E        -1.266  -1.202  -1.223  -1.263  -1.207  -1.186  -0.971  -0.906  -0.847
323   E        -0.999  -0.948  -0.783  -1.116  -1.049  -0.802  -0.945  -0.881  -0.694
324   N        -1.263  -1.284  -1.359  -0.925  -0.946  -1.093  -0.839  -0.857  -0.853
325   V        -0.470  -0.773  -0.886  -0.219  -0.657  -0.972  -0.229  -0.542  -0.650
326   K         0.014  -0.116  -0.080  -0.045  -0.248  -0.184  -0.157  -0.333  -0.275
327   K        -0.776  -0.832  -0.944  -0.533  -0.661  -0.812  -0.600  -0.672  -0.709
328   E        -0.039  -0.012  -0.061  -0.125  -0.098  -0.126  -0.282  -0.258  -0.270
329   N        -0.822  -0.867  -0.757  -0.727  -0.792  -0.690  -0.781  -0.792  -0.672
330   R        -0.669  -0.542  -0.517  -0.684  -0.457  -0.448  -0.781  -0.647  -0.576
331   R         0.470   0.306   0.332   0.743   0.468   0.462   0.318   0.053   0.040
332   Q        -0.662  -0.614  -0.522  -0.778  -0.750  -0.623  -0.729  -0.680  -0.570
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   N        -1.358  -1.350  -1.364  -0.989  -0.902  -0.946  -0.945  -0.903  -0.859
335   V         0.528   0.523   0.419   0.426   0.432   0.236   0.406   0.396   0.164
336   T        -0.614  -0.604  -0.516  -0.575  -0.599  -0.474  -0.706  -0.687  -0.568
337   I        -0.641  -0.621  -0.518  -0.653  -0.675  -0.491  -0.759  -0.718  -0.579
338   D        -1.266  -1.123  -1.220  -1.245  -1.046  -1.156  -0.971  -0.845  -0.842
339   R        -1.410  -1.316  -1.233  -1.266  -1.165  -1.027  -1.077  -0.975  -0.851
340   T         0.079   0.107  -0.044   0.090   0.071  -0.117  -0.071  -0.088  -0.239
341   R        -0.639  -0.640  -0.690  -0.485  -0.499  -0.507  -0.574  -0.569  -0.606
342   L        -0.340  -0.241  -0.118  -0.851  -0.711  -0.526  -0.600  -0.478  -0.329
343   Y        -0.138  -0.139  -0.523   0.440   0.416  -0.048   0.035   0.011  -0.411
344   S        -0.862  -0.841  -0.756  -0.756  -0.725  -0.531  -0.812  -0.774  -0.667
345   I        -0.604  -0.460  -0.646  -0.765  -0.651  -0.774  -0.600  -0.477  -0.571
346   G        -1.496  -1.443  -1.273  -1.513  -1.312  -1.161  -1.130  -1.053  -0.878
347   G        -1.126  -1.204  -1.198  -0.969  -1.046  -1.109  -0.812  -0.849  -0.818
348   H        -1.352  -1.397  -1.270  -1.181  -1.215  -0.988  -1.024  -1.037  -0.878
349   E        -0.059   0.050  -0.225   0.095   0.248  -0.147  -0.097   0.040  -0.262
350   V        -0.638  -0.658  -0.718  -0.648  -0.633  -0.741  -0.580  -0.582  -0.625
351   P        -1.182  -1.023  -1.046  -1.174  -0.970  -1.071  -0.981  -0.855  -0.796
352   F        -0.008   0.123  -0.018  -0.061   0.173   0.029  -0.256  -0.086  -0.209
353   G         0.281   0.319   0.245   0.247   0.288   0.128   0.087   0.112  -0.075
354   G        -0.790  -0.610  -0.728  -0.767  -0.522  -0.703  -0.714  -0.531  -0.628
355   I        -1.613  -1.542  -1.461  -1.617  -1.561  -1.430  -1.133  -1.067  -0.931
356   T        -1.137  -1.002  -1.009  -1.185  -1.009  -0.987  -0.942  -0.817  -0.768
357   F        -0.475  -0.336  -0.218  -0.696  -0.546  -0.369  -0.723  -0.585  -0.436
358   P        -0.365  -0.393  -0.448  -0.345  -0.357  -0.437  -0.460  -0.463  -0.493
359   A        -0.356  -0.368  -0.241  -0.460  -0.508  -0.329  -0.592  -0.598  -0.457
360   D        -0.642  -0.650  -0.535  -0.746  -0.784  -0.631  -0.723  -0.722  -0.592
361   P         0.125  -0.066  -0.294   0.568   0.323  -0.020   0.229  -0.008  -0.313
362   E         0.631   0.499   0.391   0.815   0.630   0.389   0.585   0.377   0.139
363   A        -0.421  -0.621  -0.702  -0.226  -0.518  -0.660  -0.305  -0.523  -0.597
364   R        -0.731  -0.759  -0.712  -0.782  -0.827  -0.681  -0.721  -0.727  -0.628
365   R        -1.105  -1.072  -1.004  -1.011  -0.978  -0.884  -0.929  -0.883  -0.771
366   A        -0.721  -0.762  -0.748  -0.727  -0.865  -0.854  -0.662  -0.727  -0.658
367   A        -0.869  -0.899  -0.760  -0.807  -0.863  -0.672  -0.840  -0.831  -0.671
368   T        -1.767  -1.700  -1.628  -1.573  -1.562  -1.460  -1.167  -1.111  -0.977
369   E        -0.386  -0.189  -0.327  -0.478  -0.199  -0.336  -0.513  -0.310  -0.388
370   F         0.150   0.103   0.252   0.227   0.164   0.382  -0.229  -0.271  -0.099
371   V        -0.328  -0.465  -0.472  -0.043  -0.318  -0.400  -0.362  -0.538  -0.523
372   K        -1.599  -1.506  -1.420  -1.330  -1.197  -1.063  -1.130  -1.030  -0.906
373   F        -0.999  -0.972  -0.796  -1.009  -0.968  -0.760  -0.945  -0.891  -0.702
374   I        -0.039  -0.171  -0.078  -0.335  -0.480  -0.352  -0.282  -0.395  -0.286
375   N        -1.736  -1.702  -1.619  -1.524  -1.533  -1.411  -1.157  -1.110  -0.971
376   P         0.551   0.232   0.072   0.930   0.508   0.257   0.645   0.204  -0.053
377   K        -1.136  -1.030  -1.006  -0.901  -0.713  -0.643  -0.971  -0.852  -0.770
378   I        -0.432  -0.210  -0.358  -0.576  -0.268  -0.392  -0.574  -0.323  -0.419
379   S        -1.126  -1.210  -1.234  -0.895  -1.010  -1.063  -0.812  -0.899  -0.848
380   D        -0.862  -0.561  -0.697  -0.839  -0.382  -0.634  -0.812  -0.499  -0.605
381   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   Q        -0.333  -0.418  -0.634  -0.092  -0.190  -0.497  -0.203  -0.301  -0.532
383   I         0.614   0.582   0.455   0.542   0.480   0.285   0.459   0.365   0.184
384   H        -0.054  -0.067  -0.092  -0.155  -0.220  -0.202  -0.256  -0.289  -0.289
385   H         0.391   0.123   0.023   0.817   0.427   0.299   0.380  -0.006  -0.143
386   I        -0.728  -0.886  -0.794  -0.728  -0.917  -0.748  -0.675  -0.813  -0.693
387   P         0.528   0.517   0.403   0.740   0.724   0.570   0.406   0.343   0.156
388   A        -0.243  -0.352  -0.385  -0.388  -0.607  -0.697  -0.309  -0.443  -0.448
389   R        -0.001  -0.191  -0.334   0.202  -0.040  -0.254   0.062  -0.177  -0.362
390   V        -0.169  -0.177  -0.120  -0.507  -0.481  -0.466  -0.388  -0.350  -0.317
391   Y         0.188   0.095  -0.018   0.252   0.139  -0.054   0.115   0.007  -0.178
392   K        -1.352  -1.280  -1.237  -1.396  -1.345  -1.276  -1.024  -0.967  -0.856
393   N        -0.562  -0.316  -0.448  -0.647  -0.366  -0.492  -0.680  -0.444  -0.513
394   G         2.262   2.361   2.590   2.220   2.360   2.739   2.605   2.773   3.215
395   L         2.262   2.361   2.590   2.211   2.359   2.729   2.605   2.773   3.215
396   Y        -0.830  -0.736  -0.716  -0.848  -0.731  -0.648  -0.812  -0.727  -0.637
397   D        -0.554  -0.733  -0.717  -0.504  -0.764  -0.770  -0.521  -0.678  -0.623
398   V         0.410   0.581   0.415   0.169   0.423   0.160   0.194   0.442   0.168
399   P        -0.450  -0.528  -0.484  -0.288  -0.431  -0.372  -0.521  -0.620  -0.544
400   R         0.202   0.185  -0.211   0.602   0.594   0.053   0.327   0.318  -0.196
401   I         0.136   0.249   0.302  -0.311  -0.155  -0.061  -0.256  -0.118  -0.037
402   L         0.551   0.424   0.131   0.780   0.647   0.294   0.645   0.465   0.039
403   E        -0.148  -0.148  -0.082  -0.136  -0.098  -0.004  -0.415  -0.382  -0.296
404   D        -0.281  -0.297  -0.572  -0.080  -0.090  -0.429  -0.176  -0.190  -0.461
405   I        -0.718  -0.757  -0.568  -0.882  -0.881  -0.603  -0.812  -0.818  -0.621
406   K         0.326   0.319   0.302   0.367   0.297   0.263   0.035  -0.004  -0.033
407   I        -0.776  -0.719  -0.878  -0.521  -0.418  -0.674  -0.600  -0.515  -0.654
408   G        -0.117   0.146   0.011  -0.267   0.142  -0.022  -0.362  -0.002  -0.168
409   K         0.770   0.675   0.253   1.024   0.949   0.430   0.963   0.836   0.225
410   N        -0.587  -0.692  -0.504  -0.864  -0.975  -0.735  -0.706  -0.764  -0.567
411   S         0.188   0.150  -0.016   0.275   0.246  -0.072   0.115   0.069  -0.195
412   G         0.741   0.817   0.862   0.346   0.427   0.562   0.300   0.384   0.463
413   E         0.490   0.524   0.669   0.302   0.265   0.458   0.062   0.062   0.196
414   K         2.262   2.361   2.590   2.208   2.369   2.726   2.605   2.773   3.215
415   L        -0.200  -0.211  -0.149  -0.461  -0.438  -0.361  -0.441  -0.436  -0.361
416   V         2.262   2.361   2.590   2.149   2.284   2.666   2.605   2.773   3.215
417   A         0.168   0.102   0.240   0.107  -0.019   0.165  -0.176  -0.274  -0.116
418   V        -0.333  -0.158  -0.519   0.124   0.370  -0.191  -0.203   0.014  -0.397
419   L        -0.373  -0.285  -0.167  -0.834  -0.665  -0.550  -0.627  -0.511  -0.385
420   N        -0.786  -0.861  -0.748  -0.723  -0.811  -0.690  -0.747  -0.786  -0.652
421   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
422   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
423   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
424   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
425   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
426   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
427   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
428   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
429   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
430   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
431   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
432   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
433   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
434   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
435   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
436   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
437   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
438   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25608
Output conservation file - output/P25608
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
