1     M         1.113   1.170   1.241   1.331   1.415   1.513   1.198   1.275   1.385
2     L        -0.990  -1.084  -1.016  -1.149  -1.233  -1.130  -1.043  -1.105  -0.995
3     R        -1.478  -1.459  -1.398  -1.460  -1.476  -1.347  -1.364  -1.307  -1.175
4     S        -1.177  -1.038  -1.021  -1.277  -1.032  -1.025  -1.257  -1.057  -0.999
5     L        -1.994  -1.893  -1.738  -2.127  -1.921  -1.751  -1.648  -1.518  -1.311
6     L        -1.041  -1.025  -1.029  -1.181  -1.105  -1.132  -1.079  -1.050  -1.006
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    Q        -1.678  -1.594  -1.435  -1.853  -1.689  -1.492  -1.534  -1.414  -1.204
24    S        -1.593  -1.557  -1.430  -1.394  -1.376  -1.227  -1.458  -1.387  -1.200
25    G        -1.193  -1.181  -1.042  -1.410  -1.448  -1.224  -1.269  -1.220  -1.020
26    H        -1.193  -1.036  -1.036  -1.321  -1.117  -1.083  -1.269  -1.064  -1.013
27    R        -1.041  -1.027  -1.015  -0.907  -0.906  -0.863  -1.079  -1.052  -0.991
28    R         0.138   0.204   0.132   0.124   0.215   0.093  -0.083   0.023  -0.150
29    V        -1.041  -1.040  -1.030  -1.068  -1.078  -1.062  -1.079  -1.050  -1.006
30    V        -1.041  -0.964  -1.029  -1.104  -1.017  -1.113  -1.079  -0.964  -1.006
31    A        -1.593  -1.485  -1.415  -1.499  -1.338  -1.247  -1.458  -1.312  -1.187
32    S        -1.593  -1.525  -1.417  -1.820  -1.718  -1.572  -1.458  -1.350  -1.189
33    S        -1.193  -1.125  -1.040  -1.496  -1.392  -1.250  -1.269  -1.160  -1.019
34    C        -1.193  -1.110  -1.041  -1.294  -1.187  -1.014  -1.269  -1.148  -1.020
35    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    T        -1.591  -1.513  -1.410  -1.575  -1.420  -1.299  -1.470  -1.353  -1.184
37    M        -2.493  -2.386  -2.216  -2.244  -2.121  -1.861  -1.790  -1.665  -1.446
38    V        -1.892  -1.798  -1.713  -1.829  -1.650  -1.546  -1.577  -1.447  -1.294
39    R        -1.478  -1.497  -1.412  -1.529  -1.629  -1.455  -1.364  -1.344  -1.185
40    C        -1.591  -1.459  -1.408  -1.561  -1.375  -1.240  -1.470  -1.318  -1.183
41    S        -1.779  -1.644  -1.695  -1.603  -1.403  -1.441  -1.470  -1.303  -1.280
42    S        -0.162  -0.338  -0.482  -0.141  -0.370  -0.558  -0.190  -0.439  -0.630
43    S         0.460   0.589   0.236   0.402   0.583   0.111   0.451   0.642   0.045
44    S         0.460   0.252   0.202   0.372   0.086  -0.028   0.451   0.108  -0.019
45    T         0.460   0.523   0.239   0.587   0.676   0.264   0.451   0.545   0.050
46    S         1.113   1.170   1.241   0.958   1.055   1.161   1.198   1.275   1.385
47    A         0.460   0.252   0.202   0.436   0.143   0.065   0.451   0.108  -0.019
48    L        -0.448  -0.457  -0.532  -0.627  -0.675  -0.676  -0.617  -0.665  -0.706
49    A         0.138   0.075   0.107  -0.011  -0.139  -0.085  -0.083  -0.210  -0.198
50    Y         1.113   1.170   1.241   1.331   1.418   1.513   1.198   1.275   1.385
51    K         1.113   1.170   1.241   1.225   1.314   1.413   1.198   1.275   1.385
52    Q        -0.763  -0.673  -0.566  -0.918  -0.813  -0.639  -1.043  -0.900  -0.746
53    M        -0.162  -0.058  -0.448  -0.215  -0.079  -0.558  -0.190  -0.041  -0.582
54    H         0.460   0.467   0.224   0.683   0.709   0.319   0.451   0.461   0.023
55    R        -0.162  -0.274  -0.470  -0.018  -0.224  -0.485  -0.190  -0.362  -0.613
56    H        -0.448  -0.342  -0.489  -0.292  -0.121  -0.368  -0.617  -0.433  -0.640
57    A        -1.918  -1.850  -1.733  -1.750  -1.710  -1.533  -1.590  -1.491  -1.308
58    T        -1.574  -1.552  -1.425  -1.574  -1.545  -1.373  -1.451  -1.388  -1.196
59    R        -0.748  -0.930  -1.003  -0.559  -0.878  -0.958  -0.723  -0.931  -0.978
60    P         0.460   0.467   0.224   0.546   0.566   0.169   0.451   0.461   0.023
61    P        -0.162  -0.338  -0.482   0.018  -0.236  -0.448  -0.190  -0.439  -0.630
62    L         0.460   0.252   0.202   0.342   0.100   0.051   0.451   0.108  -0.019
63    P         0.460   0.252   0.202   0.561   0.277   0.170   0.451   0.108  -0.019
64    T        -0.990  -1.109  -1.020  -0.983  -1.167  -1.073  -1.043  -1.135  -0.998
65    L        -1.478  -1.303  -1.378  -1.541  -1.233  -1.389  -1.364  -1.144  -1.156
66    D        -0.034   0.056   0.110  -0.214  -0.074   0.003  -0.403  -0.246  -0.191
67    T        -0.162  -0.385  -0.498   0.009  -0.320  -0.538  -0.190  -0.499  -0.652
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    P         1.113   1.170   1.241   1.130   1.216   1.323   1.198   1.275   1.385
70    S        -1.177  -1.193  -1.036  -1.356  -1.370  -1.130  -1.257  -1.221  -1.014
71    W         0.460   0.252   0.202   0.805   0.499   0.355   0.451   0.108  -0.019
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    N        -0.990  -1.017  -1.008  -1.013  -1.042  -0.988  -1.043  -1.046  -0.986
74    A        -0.162  -0.321  -0.485  -0.138  -0.402  -0.627  -0.190  -0.419  -0.634
75    N        -0.990  -1.087  -1.028  -0.784  -0.914  -0.842  -1.043  -1.109  -1.005
76    S        -1.177  -1.229  -1.049  -1.416  -1.482  -1.199  -1.257  -1.260  -1.029
77    A         1.113   1.170   1.241   1.002   1.070   1.203   1.198   1.275   1.385
78    V         0.460   0.543   0.230   0.443   0.554   0.119   0.451   0.574   0.033
79    S         1.113   1.170   1.241   0.958   1.055   1.161   1.198   1.275   1.385
80    S         0.138   0.032   0.099  -0.030  -0.190  -0.086  -0.083  -0.291  -0.213
81    I         1.113   1.170   1.241   1.126   1.215   1.320   1.198   1.275   1.385
82    I         0.138   0.082   0.106  -0.145  -0.238  -0.204  -0.083  -0.197  -0.200
83    Y         0.460   0.252   0.202   0.792   0.535   0.431   0.451   0.108  -0.019
84    E         0.460   0.252   0.202   0.486   0.178   0.060   0.451   0.108  -0.019
85    T         0.460   0.543   0.230   0.601   0.711   0.284   0.451   0.574   0.033
86    P         1.113   1.170   1.241   1.130   1.216   1.323   1.198   1.275   1.385
87    A        -1.478  -1.532  -1.409  -1.487  -1.511  -1.325  -1.364  -1.364  -1.183
88    P        -0.162  -0.321  -0.485   0.021  -0.193  -0.446  -0.190  -0.419  -0.634
89    S         0.460   0.252   0.202   0.389   0.118   0.019   0.451   0.108  -0.019
90    R        -0.990  -1.076  -1.015  -0.926  -1.077  -1.052  -1.043  -1.097  -0.991
91    Q        -0.576  -0.523  -0.535  -0.704  -0.629  -0.608  -0.830  -0.751  -0.712
92    P         0.460   0.252   0.202   0.561   0.277   0.170   0.451   0.108  -0.019
93    R        -1.064  -0.966  -1.002  -1.054  -0.895  -0.923  -1.150  -1.001  -0.981
94    K         1.113   1.170   1.241   1.225   1.314   1.413   1.198   1.275   1.385
95    Q        -0.448  -0.512  -0.541  -0.345  -0.503  -0.566  -0.617  -0.723  -0.717
96    H         1.113   1.170   1.241   1.252   1.341   1.439   1.198   1.275   1.385
97    V         0.460   0.467   0.224   0.443   0.461   0.110   0.451   0.461   0.023
98    L         0.138   0.050   0.106  -0.087  -0.213  -0.100  -0.083  -0.257  -0.200
99    N         1.113   1.170   1.241   1.225   1.305   1.413   1.198   1.275   1.385
100   C         1.113   1.170   1.241   1.352   1.435   1.534   1.198   1.275   1.385
101   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
102   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
103   Q         1.113   1.170   1.241   1.244   1.333   1.432   1.198   1.275   1.385
104   N         1.113   1.170   1.241   1.225   1.305   1.413   1.198   1.275   1.385
105   E         1.113   1.170   1.241   1.077   1.151   1.273   1.198   1.275   1.385
106   P         1.113   1.170   1.241   1.130   1.216   1.323   1.198   1.275   1.385
107   G         1.113   1.170   1.241   1.199   1.281   1.388   1.198   1.275   1.385
108   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
109   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
110   S         1.113   1.170   1.241   0.958   1.055   1.161   1.198   1.275   1.385
111   R        -0.748  -0.541  -0.956  -0.627  -0.339  -1.013  -0.723  -0.446  -0.925
112   V        -0.162  -0.274  -0.470  -0.157  -0.370  -0.661  -0.190  -0.362  -0.613
113   S         0.460   0.523   0.239   0.372   0.477   0.041   0.451   0.545   0.050
114   G         0.460   0.597   0.236   0.608   0.794   0.238   0.451   0.654   0.045
115   T         0.138   0.032   0.099   0.127  -0.077   0.000  -0.083  -0.291  -0.213
116   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
117   A         1.113   1.170   1.241   1.002   1.070   1.203   1.198   1.275   1.385
118   A         0.460   0.523   0.239   0.411   0.491   0.064   0.451   0.545   0.050
119   R         1.113   1.170   1.241   1.111   1.184   1.306   1.198   1.275   1.385
120   G         1.113   1.170   1.241   1.199   1.281   1.388   1.198   1.275   1.385
121   F         1.113   1.170   1.241   1.292   1.371   1.476   1.198   1.275   1.385
122   N         1.113   1.170   1.241   1.225   1.305   1.413   1.198   1.275   1.385
123   I         1.113   1.170   1.241   1.126   1.215   1.320   1.198   1.275   1.385
124   D         1.113   1.170   1.241   1.195   1.282   1.385   1.198   1.275   1.385
125   S         1.113   1.170   1.241   0.958   1.055   1.161   1.198   1.275   1.385
126   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
127   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
128   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
129   C         0.460   0.589   0.236   0.821   0.985   0.527   0.451   0.642   0.045
130   N        -0.162  -0.274  -0.482   0.051  -0.144  -0.519  -0.190  -0.362  -0.630
131   T         1.113   1.170   1.241   1.154   1.233   1.347   1.198   1.275   1.385
132   E         1.113   1.170   1.241   1.077   1.151   1.273   1.198   1.275   1.385
133   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
134   K        -0.748  -0.930  -1.003  -0.469  -0.757  -0.918  -0.723  -0.931  -0.978
135   D         0.460   0.252   0.202   0.642   0.375   0.272   0.451   0.108  -0.019
136   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
137   S         1.113   1.170   1.241   0.958   1.055   1.161   1.198   1.275   1.385
138   R         1.113   1.170   1.241   1.111   1.184   1.306   1.198   1.275   1.385
139   M         1.113   1.170   1.241   1.331   1.415   1.513   1.198   1.275   1.385
140   T         1.113   1.170   1.241   1.154   1.233   1.347   1.198   1.275   1.385
141   I         1.113   1.170   1.241   1.126   1.215   1.320   1.198   1.275   1.385
142   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
143   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
144   Q        -1.591  -1.494  -1.411  -1.463  -1.336  -1.220  -1.470  -1.335  -1.185
145   G         1.113   1.170   1.241   1.199   1.281   1.388   1.198   1.275   1.385
146   Q         0.460   0.252   0.202   0.660   0.361   0.227   0.451   0.108  -0.019
147   D         1.113   1.170   1.241   1.195   1.282   1.385   1.198   1.275   1.385
148   G        -0.448  -0.563  -0.527  -0.415  -0.591  -0.595  -0.617  -0.740  -0.696
149   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
150   V        -0.034   0.052   0.116  -0.309  -0.172  -0.081  -0.403  -0.253  -0.181
151   E         1.113   1.170   1.241   1.077   1.151   1.273   1.198   1.275   1.385
152   Q         1.113   1.170   1.241   1.244   1.333   1.432   1.198   1.275   1.385
153   A         1.113   1.170   1.241   1.002   1.070   1.203   1.198   1.275   1.385
154   R         0.460   0.252   0.202   0.559   0.282   0.201   0.451   0.108  -0.019
155   R         1.113   1.170   1.241   1.111   1.184   1.306   1.198   1.275   1.385
156   Q         1.113   1.170   1.241   1.244   1.333   1.432   1.198   1.275   1.385
157   I         0.460   0.467   0.224   0.524   0.549   0.118   0.451   0.461   0.023
158   E         1.113   1.170   1.241   1.077   1.151   1.273   1.198   1.275   1.385
159   D         1.113   1.170   1.241   1.195   1.282   1.385   1.198   1.275   1.385
160   L         0.460   0.252   0.202   0.307   0.034  -0.049   0.451   0.108  -0.019
161   V         0.460   0.597   0.239   0.443   0.618   0.135   0.451   0.654   0.050
162   P         0.460   0.252   0.202   0.539   0.242   0.108   0.451   0.108  -0.019
163   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
164   Y        -0.576  -0.520  -0.536  -0.316  -0.229  -0.233  -0.830  -0.745  -0.712
165   A         0.460   0.543   0.230   0.418   0.520   0.067   0.451   0.574   0.033
166   V         1.113   1.170   1.241   1.010   1.088   1.211   1.198   1.275   1.385
167   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
168   D         1.113   1.170   1.241   1.195   1.282   1.385   1.198   1.275   1.385
169   Y         1.113   1.170   1.241   1.331   1.418   1.513   1.198   1.275   1.385
170   T        -0.089  -0.037   0.090  -0.417  -0.327  -0.128  -0.510  -0.425  -0.230
171   N        -0.748  -0.915  -1.001  -0.393  -0.634  -0.757  -0.723  -0.916  -0.975
172   S        -0.576  -0.665  -0.541  -0.871  -0.961  -0.766  -0.830  -0.890  -0.716
173   E        -0.990  -1.023  -1.020  -1.073  -1.184  -1.155  -1.043  -1.068  -0.999
174   I        -0.162  -0.385  -0.498  -0.006  -0.292  -0.526  -0.190  -0.499  -0.652
175   I         0.138   0.032   0.099   0.063  -0.156  -0.091  -0.083  -0.291  -0.213
176   K        -0.448  -0.537  -0.539  -0.332  -0.501  -0.506  -0.617  -0.741  -0.715
177   R         1.113   1.170   1.241   1.111   1.184   1.306   1.198   1.275   1.385
178   E         1.113   1.170   1.241   1.077   1.151   1.273   1.198   1.275   1.385
179   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
180   V         0.138   0.303   0.180  -0.185   0.077  -0.138  -0.083   0.195  -0.058
181   M        -0.034   0.085   0.126  -0.313  -0.142  -0.057  -0.403  -0.192  -0.162
182   A         0.460   0.543   0.230   0.439   0.539   0.123   0.451   0.574   0.033
183   R         0.138   0.032   0.099   0.118  -0.070   0.028  -0.083  -0.291  -0.213
184   I        -0.034   0.039   0.102  -0.309  -0.194  -0.104  -0.403  -0.277  -0.208
185   S         0.460   0.467   0.224   0.406   0.443   0.103   0.451   0.461   0.023
186   L         0.138   0.169   0.133  -0.145  -0.095  -0.163  -0.083  -0.038  -0.148
187   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
188   G         1.113   1.170   1.241   1.199   1.281   1.388   1.198   1.275   1.385
189   T        -0.748  -0.515  -0.957  -0.593  -0.264  -0.969  -0.723  -0.416  -0.925
190   E         0.460   0.252   0.202   0.520   0.241   0.158   0.451   0.108  -0.019
191   Y         0.460   0.252   0.202   0.781   0.515   0.401   0.451   0.108  -0.019
192   F         1.113   1.170   1.241   1.292   1.371   1.476   1.198   1.275   1.385
193   E        -0.576  -0.489  -0.535  -0.608  -0.495  -0.491  -0.830  -0.721  -0.711
194   D        -0.089  -0.025   0.097  -0.301  -0.212  -0.019  -0.510  -0.400  -0.217
195   L         0.460   0.252   0.202   0.326   0.072   0.007   0.451   0.108  -0.019
196   L        -0.576  -0.670  -0.543  -0.839  -0.909  -0.701  -0.830  -0.897  -0.719
197   L        -1.779  -1.733  -1.710  -1.752  -1.708  -1.678  -1.470  -1.399  -1.291
198   H        -0.448  -0.532  -0.522  -0.302  -0.415  -0.450  -0.617  -0.696  -0.687
199   H         0.460   0.252   0.202   0.662   0.365   0.217   0.451   0.108  -0.019
200   H        -1.892  -1.769  -1.709  -1.608  -1.468  -1.352  -1.577  -1.425  -1.291
201   T        -1.892  -1.788  -1.710  -1.769  -1.563  -1.452  -1.577  -1.442  -1.292
202   S        -1.193  -1.210  -1.057  -1.294  -1.316  -1.089  -1.269  -1.243  -1.035
203   T        -0.391  -0.340  -0.515  -0.239  -0.152  -0.437  -0.510  -0.427  -0.676
204   N        -1.678  -1.621  -1.435  -1.753  -1.670  -1.398  -1.534  -1.437  -1.204
205   A        -0.641  -0.648  -0.563  -0.765  -0.771  -0.669  -0.889  -0.866  -0.742
206   G        -0.641  -0.606  -0.560  -0.719  -0.711  -0.604  -0.889  -0.834  -0.740
207   A        -1.197  -1.096  -1.044  -1.447  -1.256  -1.278  -1.261  -1.112  -1.021
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   Q        -1.918  -1.864  -1.733  -1.820  -1.766  -1.510  -1.590  -1.502  -1.308
219   E        -1.445  -1.428  -1.404  -1.438  -1.463  -1.435  -1.311  -1.271  -1.178
220   L        -1.918  -1.864  -1.733  -1.820  -1.734  -1.577  -1.590  -1.502  -1.308
221   V        -0.758  -0.707  -0.577  -1.062  -1.010  -0.800  -1.032  -0.947  -0.761
222   A        -1.918  -1.825  -1.723  -2.121  -1.936  -1.817  -1.590  -1.473  -1.301
223   E        -1.445  -1.428  -1.404  -1.354  -1.327  -1.315  -1.311  -1.271  -1.178
224   I        -1.064  -1.024  -1.019  -1.201  -1.151  -1.132  -1.150  -1.063  -0.998
225   R        -1.478  -1.500  -1.412  -1.354  -1.385  -1.243  -1.364  -1.346  -1.186
226   E        -0.763  -0.679  -0.572  -0.992  -0.879  -0.690  -1.043  -0.906  -0.754
227   K        -0.990  -0.850  -0.986  -0.865  -0.611  -0.841  -1.043  -0.836  -0.960
228   Q        -1.591  -1.568  -1.420  -1.536  -1.528  -1.283  -1.470  -1.402  -1.192
229   F        -0.162  -0.282  -0.478   0.208   0.026  -0.240  -0.190  -0.371  -0.625
230   H         0.460   0.252   0.202   0.695   0.425   0.312   0.451   0.108  -0.019
231   P         0.460   0.252   0.202   0.556   0.268   0.156   0.451   0.108  -0.019
232   A        -0.990  -1.013  -1.008  -1.047  -1.058  -1.047  -1.043  -1.045  -0.985
233   N        -0.162  -0.385  -0.498   0.077  -0.268  -0.485  -0.190  -0.499  -0.652
234   L        -0.162  -0.338  -0.482  -0.215  -0.422  -0.603  -0.190  -0.439  -0.630
235   P        -1.478  -1.505  -1.410  -1.453  -1.483  -1.313  -1.364  -1.346  -1.184
236   A        -0.448  -0.293  -0.494  -0.593  -0.361  -0.702  -0.617  -0.374  -0.648
237   S         0.460   0.252   0.202   0.406   0.153   0.067   0.451   0.108  -0.019
238   E        -0.162  -0.321  -0.485  -0.049  -0.310  -0.530  -0.190  -0.419  -0.634
239   V        -0.034   0.085   0.126  -0.380  -0.187  -0.133  -0.403  -0.192  -0.162
240   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
241   R         0.460   0.252   0.202   0.562   0.287   0.209   0.451   0.108  -0.019
242   L        -0.576  -0.466  -0.531  -0.766  -0.622  -0.627  -0.830  -0.676  -0.705
243   K         0.460   0.252   0.202   0.655   0.373   0.253   0.451   0.108  -0.019
244   H         0.460   0.252   0.202   0.668   0.369   0.234   0.451   0.108  -0.019
245   E        -0.990  -0.949  -1.013  -1.023  -1.012  -1.057  -1.043  -0.993  -0.993
246   H        -0.162  -0.338  -0.482   0.178  -0.052  -0.258  -0.190  -0.439  -0.630
247   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
248   N        -1.177  -1.165  -1.044  -1.147  -1.160  -0.964  -1.257  -1.204  -1.023
249   D        -1.177  -1.149  -1.044  -1.207  -1.208  -1.058  -1.257  -1.188  -1.023
250   I         0.460   0.523   0.239   0.543   0.641   0.196   0.451   0.545   0.050
251   T        -0.576  -0.670  -0.543  -0.726  -0.807  -0.636  -0.830  -0.897  -0.719
252   N        -1.478  -1.538  -1.419  -1.176  -1.226  -1.056  -1.364  -1.370  -1.191
253   L        -0.162  -0.077  -0.454  -0.222  -0.098  -0.582  -0.190  -0.065  -0.590
254   T         0.138   0.243   0.149   0.088   0.248   0.041  -0.083   0.093  -0.117
255   N        -1.892  -1.823  -1.717  -1.556  -1.470  -1.321  -1.577  -1.478  -1.297
256   N        -1.064  -1.092  -1.025  -0.950  -1.040  -0.914  -1.150  -1.142  -1.004
257   F         1.113   1.170   1.241   1.292   1.371   1.476   1.198   1.275   1.385
258   G         0.460   0.252   0.202   0.649   0.383   0.287   0.451   0.108  -0.019
259   G         1.113   1.170   1.241   1.199   1.281   1.388   1.198   1.275   1.385
260   R         0.138   0.082   0.106   0.190   0.079   0.062  -0.083  -0.197  -0.200
261   V        -0.034  -0.032   0.089  -0.268  -0.302  -0.121  -0.403  -0.414  -0.233
262   V        -0.448  -0.615  -0.541  -0.661  -0.953  -0.878  -0.617  -0.815  -0.716
263   D         1.113   1.170   1.241   1.195   1.282   1.385   1.198   1.275   1.385
264   I         1.113   1.170   1.241   1.126   1.215   1.320   1.198   1.275   1.385
265   S        -0.448  -0.271  -0.497  -0.623  -0.352  -0.683  -0.617  -0.357  -0.654
266   E        -0.690  -0.669  -0.572  -0.795  -0.785  -0.623  -0.937  -0.901  -0.755
267   T        -1.478  -1.522  -1.412  -1.331  -1.410  -1.210  -1.364  -1.356  -1.185
268   S        -0.576  -0.674  -0.545  -0.737  -0.841  -0.642  -0.830  -0.902  -0.722
269   C        -0.576  -0.674  -0.545  -0.550  -0.669  -0.508  -0.830  -0.902  -0.722
270   I         0.460   0.589   0.236   0.543   0.721   0.191   0.451   0.642   0.045
271   V         0.460   0.252   0.202   0.407   0.088  -0.034   0.451   0.108  -0.019
272   E         1.113   1.170   1.241   1.077   1.151   1.273   1.198   1.275   1.385
273   L         0.460   0.467   0.224   0.290   0.312  -0.059   0.451   0.461   0.023
274   S        -0.162  -0.321  -0.485  -0.123  -0.333  -0.518  -0.190  -0.419  -0.634
275   A         1.113   1.170   1.241   1.002   1.070   1.203   1.198   1.275   1.385
276   K         0.460   0.252   0.202   0.661   0.386   0.270   0.451   0.108  -0.019
277   P         1.113   1.170   1.241   1.130   1.216   1.323   1.198   1.275   1.385
278   T        -1.291  -1.364  -1.391  -1.251  -1.354  -1.398  -1.150  -1.208  -1.166
279   R         1.113   1.170   1.241   1.111   1.184   1.306   1.198   1.275   1.385
280   I        -0.089  -0.031   0.091  -0.400  -0.318  -0.121  -0.510  -0.413  -0.230
281   S         0.138   0.032   0.099  -0.040  -0.202  -0.105  -0.083  -0.291  -0.213
282   A        -0.576  -0.665  -0.541  -0.865  -0.935  -0.743  -0.830  -0.890  -0.716
283   F         1.113   1.170   1.241   1.292   1.371   1.476   1.198   1.275   1.385
284   L         0.138   0.285   0.169  -0.145   0.083  -0.103  -0.083   0.164  -0.079
285   K        -1.291  -1.299  -1.386  -0.951  -1.019  -1.133  -1.150  -1.145  -1.162
286   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
287   V        -0.576  -0.518  -0.530  -0.953  -0.839  -0.829  -0.830  -0.710  -0.701
288   E        -1.478  -1.538  -1.419  -1.362  -1.466  -1.275  -1.364  -1.370  -1.191
289   P         1.113   1.170   1.241   1.130   1.216   1.323   1.198   1.275   1.385
290   F         0.460   0.252   0.202   0.753   0.490   0.398   0.451   0.108  -0.019
291   G         1.113   1.170   1.241   1.199   1.281   1.388   1.198   1.275   1.385
292   V        -0.034  -0.015   0.093  -0.268  -0.260  -0.106  -0.403  -0.381  -0.224
293   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
294   E         1.113   1.170   1.241   1.077   1.151   1.273   1.198   1.275   1.385
295   C        -1.892  -1.859  -1.724  -1.850  -1.866  -1.689  -1.577  -1.502  -1.302
296   A         0.460   0.252   0.202   0.469   0.206   0.160   0.451   0.108  -0.019
297   R         1.113   1.170   1.241   1.111   1.184   1.306   1.198   1.275   1.385
298   S         0.138   0.032   0.099  -0.054  -0.228  -0.131  -0.083  -0.291  -0.213
299   G         1.113   1.170   1.241   1.199   1.281   1.388   1.198   1.275   1.385
300   M        -0.162  -0.385  -0.498   0.169  -0.162  -0.435  -0.190  -0.499  -0.652
301   M         0.460   0.252   0.202   0.741   0.437   0.287   0.451   0.108  -0.019
302   A         1.113   1.170   1.241   1.002   1.070   1.203   1.198   1.275   1.385
303   L         0.460   0.252   0.202   0.339   0.094   0.042   0.451   0.108  -0.019
304   P         0.460   0.252   0.202   0.567   0.290   0.188   0.451   0.108  -0.019
305   R         1.113   1.170   1.241   1.111   1.184   1.306   1.198   1.275   1.385
306   T        -0.162  -0.385  -0.498  -0.019  -0.371  -0.611  -0.190  -0.499  -0.652
307   P         0.460   0.543   0.230   0.581   0.699   0.273   0.451   0.574   0.033
308   L         0.460   0.252   0.202   0.326   0.072   0.007   0.451   0.108  -0.019
309   K        -2.192  -2.008  -1.967  -1.883  -1.648  -1.547  -1.684  -1.491  -1.371
310   T        -1.779  -1.776  -1.717  -1.577  -1.578  -1.544  -1.470  -1.434  -1.297
311   S        -2.192  -2.036  -1.968  -1.969  -1.728  -1.654  -1.684  -1.513  -1.372
312   T        -1.591  -1.507  -1.408  -1.483  -1.390  -1.195  -1.470  -1.349  -1.183
313   E        -0.268  -0.360  -0.491  -0.171  -0.333  -0.502  -0.336  -0.481  -0.642
314   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   A        -0.448  -0.462  -0.528  -0.509  -0.587  -0.653  -0.617  -0.647  -0.700
317   D        -0.576  -0.518  -0.530  -0.659  -0.559  -0.560  -0.830  -0.710  -0.701
318   E        -1.478  -1.420  -1.397  -1.382  -1.284  -1.251  -1.364  -1.276  -1.174
319   D        -1.779  -1.644  -1.695  -1.579  -1.351  -1.528  -1.470  -1.303  -1.280
320   E        -1.892  -1.722  -1.707  -1.806  -1.574  -1.554  -1.577  -1.398  -1.291
321   K        -0.990  -0.918  -1.020  -0.825  -0.797  -0.885  -1.043  -0.973  -1.000
322   I        -0.990  -1.027  -1.012  -1.020  -1.098  -1.015  -1.043  -1.047  -0.988
323   S        -1.591  -1.510  -1.413  -1.714  -1.553  -1.390  -1.470  -1.344  -1.186
324   E        -0.034  -0.025   0.090  -0.172  -0.190  -0.022  -0.403  -0.401  -0.231
325   I        -0.034  -0.037   0.089  -0.268  -0.319  -0.121  -0.403  -0.425  -0.233
326   V         0.460   0.252   0.202   0.468   0.204   0.142   0.451   0.108  -0.019
327   D         1.113   1.170   1.241   1.189   1.274   1.379   1.198   1.275   1.385
328   I        -0.628  -0.610  -0.558  -0.803  -0.772  -0.650  -0.893  -0.838  -0.738
329   S         0.402   0.403   0.187   0.309   0.326   0.004   0.361   0.359  -0.045
330   Q         0.402   0.403   0.187   0.569   0.578   0.170   0.361   0.359  -0.045
331   L         1.113   1.170   1.241   0.874   0.960   1.082   1.198   1.275   1.385
332   P         1.113   1.170   1.241   1.130   1.216   1.323   1.198   1.275   1.385
333   P         1.113   1.170   1.241   1.130   1.216   1.323   1.198   1.275   1.385
334   G         1.113   1.170   1.241   1.199   1.281   1.388   1.198   1.275   1.385
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25605
Output conservation file - output/P25605
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
