1     M         1.543   1.543   1.543   1.786   1.786   1.786   1.543   1.543   1.543
2     F         1.543   1.543   1.543   1.578   1.578   1.578   1.543   1.543   1.543
3     V        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
4     V        -0.645  -0.645  -0.645  -0.716  -0.716  -0.716  -0.645  -0.645  -0.645
5     D        -0.645  -0.645  -0.645  -0.795  -0.795  -0.795  -0.645  -0.645  -0.645
6     W         1.543   1.543   1.543   1.786   1.786   1.786   1.543   1.543   1.543
7     S        -0.645  -0.645  -0.645  -0.551  -0.551  -0.551  -0.645  -0.645  -0.645
8     V         1.543   1.543   1.543   1.364   1.364   1.364   1.543   1.543   1.543
9     Q        -0.645  -0.645  -0.645  -0.392  -0.392  -0.392  -0.645  -0.645  -0.645
10    L        -0.645  -0.645  -0.645  -0.795  -0.795  -0.795  -0.645  -0.645  -0.645
11    C        -0.645  -0.645  -0.645  -0.328  -0.328  -0.328  -0.645  -0.645  -0.645
12    M        -0.645  -0.645  -0.645  -0.599  -0.599  -0.599  -0.645  -0.645  -0.645
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    G        -0.645  -0.645  -0.645  -0.716  -0.716  -0.716  -0.645  -0.645  -0.645
15    V         1.543   1.543   1.543   1.364   1.364   1.364   1.543   1.543   1.543
16    I        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
17    S         1.543   1.543   1.543   1.431   1.431   1.431   1.543   1.543   1.543
18    P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
19    L        -0.645  -0.645  -0.645  -0.979  -0.979  -0.979  -0.645  -0.645  -0.645
20    F        -0.645  -0.645  -0.645  -0.815  -0.815  -0.815  -0.645  -0.645  -0.645
21    R        -0.645  -0.645  -0.645  -0.429  -0.429  -0.429  -0.645  -0.645  -0.645
22    A        -0.645  -0.645  -0.645  -0.411  -0.411  -0.411  -0.645  -0.645  -0.645
23    L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    V         1.543   1.543   1.543   1.364   1.364   1.364   1.543   1.543   1.543
50    Q        -0.645  -0.645  -0.645  -0.618  -0.618  -0.618  -0.645  -0.645  -0.645
51    L        -0.645  -0.645  -0.645  -0.958  -0.958  -0.958  -0.645  -0.645  -0.645
52    P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
53    L        -0.645  -0.645  -0.645  -0.979  -0.979  -0.979  -0.645  -0.645  -0.645
54    S        -0.645  -0.645  -0.645  -0.686  -0.686  -0.686  -0.645  -0.645  -0.645
55    I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
56    F        -0.645  -0.645  -0.645  -0.561  -0.561  -0.561  -0.645  -0.645  -0.645
57    V         1.543   1.543   1.543   1.364   1.364   1.364   1.543   1.543   1.543
58    W         1.543   1.543   1.543   1.786   1.786   1.786   1.543   1.543   1.543
59    N         1.543   1.543   1.543   1.683   1.683   1.683   1.543   1.543   1.543
60    G        -0.645  -0.645  -0.645  -0.356  -0.356  -0.356  -0.645  -0.645  -0.645
61    F        -0.645  -0.645  -0.645  -0.815  -0.815  -0.815  -0.645  -0.645  -0.645
62    Q         1.543   1.543   1.543   1.760   1.760   1.760   1.543   1.543   1.543
63    L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
64    V         1.543   1.543   1.543   1.364   1.364   1.364   1.543   1.543   1.543
65    A        -0.645  -0.645  -0.645  -0.696  -0.696  -0.696  -0.645  -0.645  -0.645
66    L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
67    P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
68    I        -0.645  -0.645  -0.645  -0.958  -0.958  -0.958  -0.645  -0.645  -0.645
69    N         1.543   1.543   1.543   1.683   1.683   1.683   1.543   1.543   1.543
70    I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
71    P        -0.645  -0.645  -0.645  -0.618  -0.618  -0.618  -0.645  -0.645  -0.645
72    L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
73    R         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
74    L        -0.645  -0.645  -0.645  -0.979  -0.979  -0.979  -0.645  -0.645  -0.645
75    F        -0.645  -0.645  -0.645  -0.735  -0.735  -0.735  -0.645  -0.645  -0.645
76    L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
77    G         1.543   1.543   1.543   1.709   1.709   1.709   1.543   1.543   1.543
78    T         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
79    S        -0.645  -0.645  -0.645  -0.845  -0.845  -0.845  -0.645  -0.645  -0.645
80    L        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
81    S        -0.645  -0.645  -0.645  -0.706  -0.706  -0.706  -0.645  -0.645  -0.645
82    R        -0.645  -0.645  -0.645  -0.392  -0.392  -0.392  -0.645  -0.645  -0.645
83    L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
84    V        -0.645  -0.645  -0.645  -0.979  -0.979  -0.979  -0.645  -0.645  -0.645
85    A        -0.645  -0.645  -0.645  -0.542  -0.542  -0.542  -0.645  -0.645  -0.645
86    Q        -0.645  -0.645  -0.645  -0.392  -0.392  -0.392  -0.645  -0.645  -0.645
87    T        -0.645  -0.645  -0.645  -0.580  -0.580  -0.580  -0.645  -0.645  -0.645
88    S        -0.645  -0.645  -0.645  -0.686  -0.686  -0.686  -0.645  -0.645  -0.645
89    T         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
92    D        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
93    F        -0.645  -0.645  -0.645  -0.523  -0.523  -0.523  -0.645  -0.645  -0.645
94    Y        -0.645  -0.645  -0.645  -0.448  -0.448  -0.448  -0.645  -0.645  -0.645
95    V         1.543   1.543   1.543   1.364   1.364   1.364   1.543   1.543   1.543
96    V        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
97    L        -0.645  -0.645  -0.645  -0.979  -0.979  -0.979  -0.645  -0.645  -0.645
98    T         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
99    L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
100   F        -0.645  -0.645  -0.645  -0.815  -0.815  -0.815  -0.645  -0.645  -0.645
101   Q         1.543   1.543   1.543   1.760   1.760   1.760   1.543   1.543   1.543
102   Y         1.543   1.543   1.543   1.786   1.786   1.786   1.543   1.543   1.543
103   F        -0.645  -0.645  -0.645  -0.735  -0.735  -0.735  -0.645  -0.645  -0.645
104   A        -0.645  -0.645  -0.645  -0.716  -0.716  -0.716  -0.645  -0.645  -0.645
105   V        -0.645  -0.645  -0.645  -0.866  -0.866  -0.866  -0.645  -0.645  -0.645
106   L        -0.645  -0.645  -0.645  -0.979  -0.979  -0.979  -0.645  -0.645  -0.645
107   C        -0.645  -0.645  -0.645  -0.570  -0.570  -0.570  -0.645  -0.645  -0.645
108   A        -0.645  -0.645  -0.645  -0.696  -0.696  -0.696  -0.645  -0.645  -0.645
109   F        -0.645  -0.645  -0.645  -0.815  -0.815  -0.815  -0.645  -0.645  -0.645
110   G         1.543   1.543   1.543   1.709   1.709   1.709   1.543   1.543   1.543
111   S        -0.645  -0.645  -0.645  -0.667  -0.667  -0.667  -0.645  -0.645  -0.645
112   I        -0.645  -0.645  -0.645  -0.876  -0.876  -0.876  -0.645  -0.645  -0.645
113   I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
114   G         1.543   1.543   1.543   1.709   1.709   1.709   1.543   1.543   1.543
115   L        -0.645  -0.645  -0.645  -0.979  -0.979  -0.979  -0.645  -0.645  -0.645
116   I        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
117   F        -0.645  -0.645  -0.645  -0.448  -0.448  -0.448  -0.645  -0.645  -0.645
118   G         1.543   1.543   1.543   1.709   1.709   1.709   1.543   1.543   1.543
119   F        -0.645  -0.645  -0.645  -0.815  -0.815  -0.815  -0.645  -0.645  -0.645
120   I        -0.645  -0.645  -0.645  -0.580  -0.580  -0.580  -0.645  -0.645  -0.645
121   L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
122   G        -0.645  -0.645  -0.645  -0.467  -0.467  -0.467  -0.645  -0.645  -0.645
123   V        -0.645  -0.645  -0.645  -0.599  -0.599  -0.599  -0.645  -0.645  -0.645
124   F        -0.645  -0.645  -0.645  -0.735  -0.735  -0.735  -0.645  -0.645  -0.645
125   H         1.543   1.543   1.543   1.850   1.850   1.850   1.543   1.543   1.543
126   S        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
127   I        -0.645  -0.645  -0.645  -0.735  -0.735  -0.735  -0.645  -0.645  -0.645
128   C        -0.645  -0.645  -0.645  -0.365  -0.365  -0.365  -0.645  -0.645  -0.645
129   G        -0.645  -0.645  -0.645  -0.429  -0.429  -0.429  -0.645  -0.645  -0.645
130   V        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
131   P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
132   S         1.543   1.543   1.543   1.431   1.431   1.431   1.543   1.543   1.543
133   V         1.543   1.543   1.543   1.364   1.364   1.364   1.543   1.543   1.543
134   Y         1.543   1.543   1.543   1.786   1.786   1.786   1.543   1.543   1.543
135   I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
136   S        -0.645  -0.645  -0.645  -0.513  -0.513  -0.513  -0.645  -0.645  -0.645
137   L        -0.645  -0.645  -0.645  -0.958  -0.958  -0.958  -0.645  -0.645  -0.645
138   E        -0.645  -0.645  -0.645  -0.429  -0.429  -0.429  -0.645  -0.645  -0.645
139   W        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
140   K         1.543   1.543   1.543   1.683   1.683   1.683   1.543   1.543   1.543
141   R        -0.645  -0.645  -0.645  -0.580  -0.580  -0.580  -0.645  -0.645  -0.645
142   W         1.543   1.543   1.543   1.786   1.786   1.786   1.543   1.543   1.543
143   F        -0.645  -0.645  -0.645  -0.580  -0.580  -0.580  -0.645  -0.645  -0.645
144   A        -0.645  -0.645  -0.645  -0.696  -0.696  -0.696  -0.645  -0.645  -0.645
145   P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
146   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
150   R         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
151   T         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
152   V        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
153   L        -0.645  -0.645  -0.645  -0.795  -0.795  -0.795  -0.645  -0.645  -0.645
154   E        -0.645  -0.645  -0.645  -0.265  -0.265  -0.265  -0.645  -0.645  -0.645
155   R        -0.645  -0.645  -0.645  -0.429  -0.429  -0.429  -0.645  -0.645  -0.645
156   A        -0.645  -0.645  -0.645  -0.775  -0.775  -0.775  -0.645  -0.645  -0.645
157   S        -0.645  -0.645  -0.645  -0.628  -0.628  -0.628  -0.645  -0.645  -0.645
158   T        -0.645  -0.645  -0.645  -0.876  -0.876  -0.876  -0.645  -0.645  -0.645
159   S        -0.645  -0.645  -0.645  -0.667  -0.667  -0.667  -0.645  -0.645  -0.645
160   I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
161   V        -0.645  -0.645  -0.645  -0.618  -0.618  -0.618  -0.645  -0.645  -0.645
162   N        -0.645  -0.645  -0.645  -0.448  -0.448  -0.448  -0.645  -0.645  -0.645
163   I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   M         1.543   1.543   1.543   1.786   1.786   1.786   1.543   1.543   1.543
168   R         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
169   G        -0.645  -0.645  -0.645  -0.467  -0.467  -0.467  -0.645  -0.645  -0.645
170   Q        -0.645  -0.645  -0.645  -0.599  -0.599  -0.599  -0.645  -0.645  -0.645
171   T        -0.645  -0.645  -0.645  -0.532  -0.532  -0.532  -0.645  -0.645  -0.645
172   I        -0.645  -0.645  -0.645  -0.599  -0.599  -0.599  -0.645  -0.645  -0.645
173   A        -0.645  -0.645  -0.645  -0.542  -0.542  -0.542  -0.645  -0.645  -0.645
174   P        -0.645  -0.645  -0.645  -0.726  -0.726  -0.726  -0.645  -0.645  -0.645
175   I        -0.645  -0.645  -0.645  -0.735  -0.735  -0.735  -0.645  -0.645  -0.645
176   P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
177   M        -0.645  -0.645  -0.645  -0.580  -0.580  -0.580  -0.645  -0.645  -0.645
178   P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
179   K        -0.645  -0.645  -0.645  -0.542  -0.542  -0.542  -0.645  -0.645  -0.645
180   P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
181   N        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
182   P         1.543   1.543   1.543   1.552   1.552   1.552   1.543   1.543   1.543
183   T        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
184   H        -0.645  -0.645  -0.645  -0.402  -0.402  -0.402  -0.645  -0.645  -0.645
185   I        -0.645  -0.645  -0.645  -0.845  -0.845  -0.845  -0.645  -0.645  -0.645
186   S        -0.645  -0.645  -0.645  -0.726  -0.726  -0.726  -0.645  -0.645  -0.645
187   K        -0.645  -0.645  -0.645  -0.374  -0.374  -0.374  -0.645  -0.645  -0.645
188   P        -0.645  -0.645  -0.645  -0.599  -0.599  -0.599  -0.645  -0.645  -0.645
189   N        -0.645  -0.645  -0.645  -0.448  -0.448  -0.448  -0.645  -0.645  -0.645
190   M        -0.645  -0.645  -0.645  -0.411  -0.411  -0.411  -0.645  -0.645  -0.645
191   K        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
192   K        -0.645  -0.645  -0.645  -0.523  -0.523  -0.523  -0.645  -0.645  -0.645
193   F        -0.645  -0.645  -0.645  -0.815  -0.815  -0.815  -0.645  -0.645  -0.645
194   H        -0.645  -0.645  -0.645  -0.383  -0.383  -0.383  -0.645  -0.645  -0.645
195   D         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   E        -0.645  -0.645  -0.645  -0.392  -0.392  -0.392  -0.645  -0.645  -0.645
201   P        -0.645  -0.645  -0.645  -0.755  -0.755  -0.755  -0.645  -0.645  -0.645
202   G         1.543   1.543   1.543   1.709   1.709   1.709   1.543   1.543   1.543
203   A        -0.645  -0.645  -0.645  -0.667  -0.667  -0.667  -0.645  -0.645  -0.645
204   D        -0.645  -0.645  -0.645  -0.561  -0.561  -0.561  -0.645  -0.645  -0.645
205   D        -0.645  -0.645  -0.645  -0.599  -0.599  -0.599  -0.645  -0.645  -0.645
206   M        -0.645  -0.645  -0.645  -0.411  -0.411  -0.411  -0.645  -0.645  -0.645
207   T        -0.645  -0.645  -0.645  -0.845  -0.845  -0.845  -0.645  -0.645  -0.645
208   I        -0.645  -0.645  -0.645  -0.580  -0.580  -0.580  -0.645  -0.645  -0.645
209   T         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
210   H        -0.645  -0.645  -0.645  -0.402  -0.402  -0.402  -0.645  -0.645  -0.645
211   D        -0.645  -0.645  -0.645  -0.485  -0.485  -0.485  -0.645  -0.645  -0.645
212   V        -0.645  -0.645  -0.645  -0.676  -0.676  -0.676  -0.645  -0.645  -0.645
213   N        -0.645  -0.645  -0.645  -0.628  -0.628  -0.628  -0.645  -0.645  -0.645
214   C        -0.645  -0.645  -0.645  -0.467  -0.467  -0.467  -0.645  -0.645  -0.645
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   Y        -0.645  -0.645  -0.645  -0.448  -0.448  -0.448  -0.645  -0.645  -0.645
226   I        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
227   T        -0.645  -0.645  -0.645  -0.845  -0.845  -0.845  -0.645  -0.645  -0.645
228   P        -0.645  -0.645  -0.645  -0.580  -0.580  -0.580  -0.645  -0.645  -0.645
229   C        -0.645  -0.645  -0.645  -0.467  -0.467  -0.467  -0.645  -0.645  -0.645
230   Q        -0.645  -0.645  -0.645  -0.283  -0.283  -0.283  -0.645  -0.645  -0.645
231   T        -0.645  -0.645  -0.645  -0.876  -0.876  -0.876  -0.645  -0.645  -0.645
232   P        -0.645  -0.645  -0.645  -0.523  -0.523  -0.523  -0.645  -0.645  -0.645
233   T        -0.645  -0.645  -0.645  -0.958  -0.958  -0.958  -0.645  -0.645  -0.645
234   N        -0.645  -0.645  -0.645  -0.542  -0.542  -0.542  -0.645  -0.645  -0.645
235   E        -0.645  -0.645  -0.645  -0.392  -0.392  -0.392  -0.645  -0.645  -0.645
236   K        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
237   I        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
238   Q        -0.645  -0.645  -0.645  -0.618  -0.618  -0.618  -0.645  -0.645  -0.645
239   H         1.543   1.543   1.543   1.850   1.850   1.850   1.543   1.543   1.543
240   Y        -0.645  -0.645  -0.645  -0.374  -0.374  -0.374  -0.645  -0.645  -0.645
241   N        -0.645  -0.645  -0.645  -0.628  -0.628  -0.628  -0.645  -0.645  -0.645
242   N        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
243   D        -0.645  -0.645  -0.645  -0.716  -0.716  -0.716  -0.645  -0.645  -0.645
244   S         1.543   1.543   1.543   1.431   1.431   1.431   1.543   1.543   1.543
245   F        -0.645  -0.645  -0.645  -0.467  -0.467  -0.467  -0.645  -0.645  -0.645
246   N        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
247   T         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
248   T        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
249   T        -0.645  -0.645  -0.645  -0.696  -0.696  -0.696  -0.645  -0.645  -0.645
250   T        -0.645  -0.645  -0.645  -0.532  -0.532  -0.532  -0.645  -0.645  -0.645
251   D        -0.645  -0.645  -0.645  -0.392  -0.392  -0.392  -0.645  -0.645  -0.645
252   D        -0.645  -0.645  -0.645  -0.686  -0.686  -0.686  -0.645  -0.645  -0.645
253   E        -0.645  -0.645  -0.645  -0.542  -0.542  -0.542  -0.645  -0.645  -0.645
254   P        -0.645  -0.645  -0.645  -0.726  -0.726  -0.726  -0.645  -0.645  -0.645
255   T        -0.645  -0.645  -0.645  -0.599  -0.599  -0.599  -0.645  -0.645  -0.645
256   D        -0.645  -0.645  -0.645  -0.686  -0.686  -0.686  -0.645  -0.645  -0.645
257   I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
258   W        -0.645  -0.645  -0.645  -0.429  -0.429  -0.429  -0.645  -0.645  -0.645
259   D         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
260   R        -0.645  -0.645  -0.645  -0.686  -0.686  -0.686  -0.645  -0.645  -0.645
261   S        -0.645  -0.645  -0.645  -0.845  -0.845  -0.845  -0.645  -0.645  -0.645
262   D         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
263   T        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
264   Y        -0.645  -0.645  -0.645  -0.599  -0.599  -0.599  -0.645  -0.645  -0.645
265   Q        -0.645  -0.645  -0.645  -0.319  -0.319  -0.319  -0.645  -0.645  -0.645
266   N        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
267   S        -0.645  -0.645  -0.645  -0.513  -0.513  -0.513  -0.645  -0.645  -0.645
268   F         1.543   1.543   1.543   1.578   1.578   1.578   1.543   1.543   1.543
269   V        -0.645  -0.645  -0.645  -0.735  -0.735  -0.735  -0.645  -0.645  -0.645
270   T        -0.645  -0.645  -0.645  -0.845  -0.845  -0.845  -0.645  -0.645  -0.645
271   N        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
272   E        -0.645  -0.645  -0.645  -0.429  -0.429  -0.429  -0.645  -0.645  -0.645
273   T        -0.645  -0.645  -0.645  -0.845  -0.845  -0.845  -0.645  -0.645  -0.645
274   L         1.543   1.543   1.543   1.282   1.282   1.282   1.543   1.543   1.543
275   M        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
276   S        -0.645  -0.645  -0.645  -0.686  -0.686  -0.686  -0.645  -0.645  -0.645
277   L        -0.645  -0.645  -0.645  -0.795  -0.795  -0.795  -0.645  -0.645  -0.645
278   S        -0.645  -0.645  -0.645  -0.845  -0.845  -0.845  -0.645  -0.645  -0.645
279   N        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
280   R         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
281   A        -0.645  -0.645  -0.645  -0.775  -0.775  -0.775  -0.645  -0.645  -0.645
282   K        -0.645  -0.645  -0.645  -0.657  -0.657  -0.657  -0.645  -0.645  -0.645
283   L        -0.645  -0.645  -0.645  -0.958  -0.958  -0.958  -0.645  -0.645  -0.645
284   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
285   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
286   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
287   R         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
288   R        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
289   N        -0.645  -0.645  -0.645  -0.392  -0.392  -0.392  -0.645  -0.645  -0.645
290   A        -0.645  -0.645  -0.645  -0.485  -0.485  -0.485  -0.645  -0.645  -0.645
291   S        -0.645  -0.645  -0.645  -0.570  -0.570  -0.570  -0.645  -0.645  -0.645
292   D        -0.645  -0.645  -0.645  -0.504  -0.504  -0.504  -0.645  -0.645  -0.645
293   A        -0.645  -0.645  -0.645  -0.374  -0.374  -0.374  -0.645  -0.645  -0.645
294   D         1.543   1.543   1.543   1.604   1.604   1.604   1.543   1.543   1.543
295   I        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
296   V        -0.645  -0.645  -0.645  -0.896  -0.896  -0.896  -0.645  -0.645  -0.645
297   N        -0.645  -0.645  -0.645  -0.392  -0.392  -0.392  -0.645  -0.645  -0.645
298   I         1.543   1.543   1.543   1.391   1.391   1.391   1.543   1.543   1.543
299   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   N        -0.645  -0.645  -0.645  -0.328  -0.328  -0.328  -0.645  -0.645  -0.645
305   S        -0.645  -0.645  -0.645  -0.686  -0.686  -0.686  -0.645  -0.645  -0.645
306   R        -0.645  -0.645  -0.645  -0.429  -0.429  -0.429  -0.645  -0.645  -0.645
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25587
Output conservation file - output/P25587
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
