1     M         2.058   2.121   2.156   2.355   2.426   2.502   2.210   2.318   2.367
2     F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     A         0.029   0.321   0.332  -0.311   0.196   0.196  -0.283   0.181   0.196
10    S        -0.986  -0.964  -0.950  -0.924  -0.994  -0.958  -0.907  -0.858  -0.829
11    S        -0.986  -0.964  -0.950  -1.152  -1.107  -1.109  -0.907  -0.858  -0.829
12    L         0.412   0.321   0.297   0.319   0.225   0.137   0.340   0.180   0.139
13    F         0.412   0.359   0.302   0.673   0.601   0.514   0.340   0.242   0.147
14    V        -0.986  -0.964  -0.950  -1.234  -1.174  -1.153  -0.907  -0.858  -0.829
15    A        -0.986  -0.964  -0.950  -0.954  -0.900  -0.903  -0.907  -0.858  -0.829
16    L         0.412   0.359   0.302   0.354   0.265   0.172   0.340   0.242   0.147
17    T         0.412   0.359   0.302   0.503   0.436   0.357   0.340   0.242   0.147
18    S        -0.986  -0.964  -0.950  -0.976  -1.038  -0.979  -0.907  -0.858  -0.829
19    A         0.412   0.359   0.302   0.366   0.354   0.234   0.340   0.242   0.147
20    A         2.058   2.121   2.156   1.899   2.053   2.070   2.210   2.318   2.367
21    S        -0.986  -0.964  -0.950  -1.188  -1.148  -1.140  -0.907  -0.858  -0.829
22    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    A         0.412   0.359   0.302   0.308   0.258   0.146   0.340   0.242   0.147
28    L         2.058   2.121   2.156   1.971   2.076   2.138   2.210   2.318   2.367
29    L        -0.986  -0.964  -0.950  -1.130  -1.063  -1.061  -0.907  -0.858  -0.829
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    L         0.412   0.359   0.302   0.467   0.415   0.341   0.340   0.242   0.147
35    L         0.412   0.321   0.297   0.580   0.411   0.365   0.340   0.180   0.139
36    P        -0.986  -0.964  -0.950  -0.842  -0.760  -0.728  -0.907  -0.858  -0.829
37    G        -0.986  -0.964  -0.950  -1.139  -1.034  -1.074  -0.907  -0.858  -0.829
38    V         2.058   2.121   2.156   1.950   2.037   2.118   2.210   2.318   2.367
39    E        -0.986  -0.964  -0.950  -1.101  -1.064  -1.017  -0.907  -0.858  -0.829
40    S        -0.986  -0.964  -0.950  -1.130  -1.076  -1.061  -0.907  -0.858  -0.829
41    H        -0.986  -0.964  -0.950  -0.710  -0.695  -0.665  -0.907  -0.858  -0.829
42    D         0.412   0.359   0.302   0.234   0.129   0.040   0.340   0.242   0.147
43    G         0.412   0.321   0.297   0.277   0.201   0.091   0.340   0.180   0.139
44    -         0.195   0.174   0.197   0.140   0.190   0.229  -0.006  -0.065  -0.030
45    -         0.195   0.174   0.197  -0.110  -0.153  -0.146  -0.006  -0.065  -0.030
46    -         0.195   0.174   0.197   0.182   0.050   0.077  -0.006  -0.065  -0.030
47    -         0.195   0.174   0.197  -0.066  -0.055  -0.026  -0.006  -0.065  -0.030
48    -         0.195   0.174   0.197   0.394   0.335   0.369  -0.006  -0.065  -0.030
49    -         2.058   2.121   2.156   2.024   2.120   2.188   2.210   2.318   2.367
50    -         0.195   0.174   0.197  -0.119  -0.173  -0.152  -0.006  -0.065  -0.030
51    -         2.058   2.121   2.156   1.940   2.029   2.109   2.210   2.318   2.367
52    -         0.195   0.174   0.197   0.131   0.135   0.172  -0.006  -0.065  -0.030
53    -         0.195   0.174   0.197   0.161   0.135   0.185  -0.006  -0.065  -0.030
54    -         0.195   0.174   0.197   0.173   0.153   0.204  -0.006  -0.065  -0.030
55    -         0.195   0.174   0.197   0.272   0.199   0.235  -0.006  -0.065  -0.030
56    V        -0.986  -0.964  -0.950  -0.954  -0.975  -0.941  -0.907  -0.858  -0.829
57    D         0.412   0.359   0.302   0.331   0.271   0.186   0.340   0.242   0.147
58    T         0.412   0.359   0.302   0.431   0.354   0.248   0.340   0.242   0.147
59    -         0.195   0.174   0.197  -0.115  -0.104  -0.099  -0.006  -0.065  -0.030
60    -         0.195   0.174   0.197  -0.097  -0.104  -0.099  -0.006  -0.065  -0.030
61    V        -0.986  -0.964  -0.950  -0.902  -0.963  -0.928  -0.907  -0.858  -0.829
62    F        -0.986  -0.964  -0.950  -0.967  -0.913  -0.882  -0.907  -0.858  -0.829
63    S        -0.986  -0.964  -0.950  -1.198  -1.180  -1.171  -0.907  -0.858  -0.829
64    T         0.412   0.321   0.297   0.305   0.171   0.139   0.340   0.180   0.139
65    K        -0.986  -0.964  -0.950  -1.101  -1.130  -1.065  -0.907  -0.858  -0.829
66    D         2.058   2.121   2.156   1.892   1.993   2.063   2.210   2.318   2.367
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    F        -0.986  -0.964  -0.950  -0.976  -0.914  -0.882  -0.907  -0.858  -0.829
69    Y         0.412   0.321   0.297   0.398   0.261   0.244   0.340   0.180   0.139
70    Q        -0.986  -0.964  -0.950  -0.924  -0.896  -0.854  -0.907  -0.858  -0.829
71    V         0.412   0.359   0.302   0.382   0.297   0.227   0.340   0.242   0.147
72    S         0.412   0.321   0.297   0.553   0.344   0.311   0.340   0.180   0.139
73    F        -0.986  -0.964  -0.950  -0.815  -0.828  -0.796  -0.907  -0.858  -0.829
74    V        -0.986  -0.964  -0.950  -1.107  -1.048  -0.983  -0.907  -0.858  -0.829
75    K        -0.986  -0.964  -0.950  -1.117  -1.038  -1.043  -0.907  -0.858  -0.829
76    S         0.412   0.321   0.297   0.333   0.170   0.118   0.340   0.180   0.139
77    I        -0.986  -0.964  -0.950  -0.902  -0.825  -0.796  -0.907  -0.858  -0.829
78    A        -0.986  -0.964  -0.950  -1.050  -0.929  -0.907  -0.907  -0.858  -0.829
79    P        -0.986  -0.964  -0.950  -0.807  -0.822  -0.784  -0.907  -0.858  -0.829
80    A         0.412   0.321   0.297   0.510   0.359   0.289   0.340   0.180   0.139
81    I         2.058   2.121   2.156   2.099   2.192   2.259   2.210   2.318   2.367
82    V        -0.986  -0.964  -0.950  -0.976  -0.942  -0.895  -0.907  -0.858  -0.829
83    N        -0.986  -0.964  -0.950  -0.970  -0.967  -0.924  -0.907  -0.858  -0.829
84    -         2.058   2.121   2.156   2.180   2.288   2.336   2.210   2.318   2.367
85    -         2.058   2.121   2.156   1.874   2.042   2.046   2.210   2.318   2.367
86    -         2.058   2.121   2.156   1.836   1.976   2.010   2.210   2.318   2.367
87    S         0.412   0.359   0.302   0.230   0.122   0.078   0.340   0.242   0.147
88    S        -0.986  -0.964  -0.950  -1.185  -1.167  -1.131  -0.907  -0.858  -0.829
89    V        -0.986  -0.964  -0.950  -0.994  -1.015  -0.949  -0.907  -0.858  -0.829
90    I        -0.986  -0.964  -0.950  -0.954  -0.833  -0.825  -0.907  -0.858  -0.829
91    F         0.412   0.321   0.297   0.435   0.318   0.286   0.340   0.180   0.139
92    H         0.412   0.321   0.297   0.485   0.385   0.361   0.340   0.180   0.139
93    D         2.058   2.121   2.156   1.892   1.993   2.063   2.210   2.318   2.367
94    V        -0.986  -0.964  -0.950  -0.866  -0.939  -0.866  -0.907  -0.858  -0.829
95    S        -0.986  -0.964  -0.950  -0.948  -0.957  -0.887  -0.907  -0.858  -0.829
96    R        -0.986  -0.964  -0.950  -0.936  -0.899  -0.878  -0.907  -0.858  -0.829
97    G         2.058   2.121   2.156   1.928   2.084   2.097   2.210   2.318   2.367
98    V        -0.986  -0.964  -0.950  -0.902  -0.923  -0.899  -0.907  -0.858  -0.829
99    A        -0.986  -0.964  -0.950  -1.107  -1.065  -1.061  -0.907  -0.858  -0.829
100   M        -0.986  -0.964  -0.950  -0.833  -0.735  -0.705  -0.907  -0.858  -0.829
101   G        -0.986  -0.964  -0.950  -1.085  -1.043  -1.043  -0.907  -0.858  -0.829
102   N         0.412   0.359   0.302   0.357   0.277   0.163   0.340   0.242   0.147
103   V         0.412   0.321   0.297   0.479   0.306   0.272   0.340   0.180   0.139
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -         0.195   0.174   0.197   0.072   0.012   0.052  -0.006  -0.065  -0.030
107   -         0.195   0.174   0.197   0.144   0.022   0.109  -0.006  -0.065  -0.030
108   -         0.195   0.174   0.197  -0.018  -0.084  -0.052  -0.006  -0.065  -0.030
109   -         0.195   0.174   0.197   0.156   0.088   0.071  -0.006  -0.065  -0.030
110   -         0.195   0.174   0.197  -0.110  -0.104  -0.119  -0.006  -0.065  -0.030
111   -         0.195   0.174   0.197  -0.150  -0.173  -0.152  -0.006  -0.065  -0.030
112   -         0.195   0.174   0.197  -0.014  -0.065  -0.046  -0.006  -0.065  -0.030
113   -         0.195   0.174   0.197  -0.084  -0.133  -0.099  -0.006  -0.065  -0.030
114   -         0.195   0.174   0.197   0.029  -0.045  -0.013  -0.006  -0.065  -0.030
115   -         0.195   0.174   0.197   0.418   0.281   0.339  -0.006  -0.065  -0.030
116   -         0.195   0.174   0.197  -0.023   0.031   0.013  -0.006  -0.065  -0.030
117   K         0.412   0.359   0.302   0.490   0.375   0.345   0.340   0.242   0.147
118   S        -0.986  -0.964  -0.950  -0.704  -0.736  -0.697  -0.907  -0.858  -0.829
119   R        -0.986  -0.964  -0.950  -0.967  -0.855  -0.837  -0.907  -0.858  -0.829
120   A        -0.986  -0.964  -0.950  -1.079  -1.027  -1.022  -0.907  -0.858  -0.829
121   S         0.412   0.321   0.297   0.361   0.134   0.142   0.340   0.180   0.139
122   I         0.412   0.321   0.297   0.382   0.237   0.219   0.340   0.180   0.139
123   F         0.412   0.321   0.297   0.604   0.467   0.432   0.340   0.180   0.139
124   N        -0.986  -0.964  -0.950  -1.152  -1.100  -1.109  -0.907  -0.858  -0.829
125   P        -0.986  -0.964  -0.950  -0.777  -0.784  -0.728  -0.907  -0.858  -0.829
126   E        -0.986  -0.964  -0.950  -1.025  -0.943  -0.916  -0.907  -0.858  -0.829
127   E        -0.986  -0.964  -0.950  -0.982  -0.910  -0.878  -0.907  -0.858  -0.829
128   T        -0.986  -0.964  -0.950  -0.795  -0.833  -0.792  -0.907  -0.858  -0.829
129   Y         0.412   0.359   0.302   0.553   0.462   0.364   0.340   0.242   0.147
130   Y        -0.986  -0.964  -0.950  -0.698  -0.625  -0.603  -0.907  -0.858  -0.829
131   D         0.412   0.321   0.297   0.398   0.236   0.190   0.340   0.180   0.139
132   W         0.412   0.359   0.302   0.671   0.598   0.498   0.340   0.242   0.147
133   E        -0.986  -0.964  -0.950  -0.627  -0.697  -0.638  -0.907  -0.858  -0.829
134   Q         0.412   0.359   0.302   0.492   0.404   0.293   0.340   0.242   0.147
135   Y         0.412   0.321   0.297   0.786   0.611   0.580   0.340   0.180   0.139
136   Q         0.412   0.359   0.302   0.451   0.349   0.231   0.340   0.242   0.147
137   V        -0.986  -0.964  -0.950  -1.010  -1.010  -0.979  -0.907  -0.858  -0.829
138   V         0.412   0.359   0.302   0.347   0.260   0.175   0.340   0.242   0.147
139   N         0.412   0.359   0.302   0.333   0.240   0.128   0.340   0.242   0.147
140   N        -0.986  -0.964  -0.950  -0.976  -0.969  -0.924  -0.907  -0.858  -0.829
141   G         0.412   0.359   0.302   0.387   0.367   0.247   0.340   0.242   0.147
142   D         0.412   0.321   0.297   0.535   0.342   0.310   0.340   0.180   0.139
143   W         0.412   0.359   0.302   0.593   0.492   0.382   0.340   0.242   0.147
144   R         0.412   0.321   0.297   0.693   0.573   0.523   0.340   0.180   0.139
145   T         0.412   0.321   0.297   0.234   0.093   0.077   0.340   0.180   0.139
146   E        -0.986  -0.964  -0.950  -0.789  -0.822  -0.784  -0.907  -0.858  -0.829
147   W         2.058   2.121   2.156   2.218   2.320   2.372   2.210   2.318   2.367
148   A        -0.986  -0.964  -0.950  -0.836  -0.809  -0.809  -0.907  -0.858  -0.829
149   P         2.058   2.121   2.156   2.218   2.296   2.372   2.210   2.318   2.367
150   A        -0.986  -0.964  -0.950  -0.985  -0.988  -0.983  -0.907  -0.858  -0.829
151   S         2.058   2.121   2.156   1.819   1.907   1.994   2.210   2.318   2.367
152   D        -0.986  -0.964  -0.950  -0.945  -0.984  -0.937  -0.907  -0.858  -0.829
153   C         2.058   2.121   2.156   2.294   2.375   2.444   2.210   2.318   2.367
154   I         0.195   0.174   0.197   0.049   0.023   0.079  -0.006  -0.065  -0.030
155   W        -0.986  -0.964  -0.950  -1.114  -1.022  -0.992  -0.907  -0.858  -0.829
156   R        -0.986  -0.964  -0.950  -0.854  -0.753  -0.744  -0.907  -0.858  -0.829
157   E         0.412   0.321   0.297   0.387   0.309   0.240   0.340   0.180   0.139
158   E         0.412   0.321   0.297   0.428   0.302   0.276   0.340   0.180   0.139
159   K        -0.986  -0.964  -0.950  -1.035  -1.001  -0.987  -0.907  -0.858  -0.829
160   D         2.058   2.121   2.156   1.892   1.993   2.063   2.210   2.318   2.367
161   N         0.029   0.321   0.332  -0.332   0.239   0.221  -0.283   0.181   0.196
162   S        -0.986  -0.964  -0.950  -0.976  -1.067  -1.017  -0.907  -0.858  -0.829
163   D        -0.986  -0.964  -0.950  -1.146  -1.072  -1.082  -0.907  -0.858  -0.829
164   E        -0.986  -0.964  -0.950  -1.035  -0.926  -0.887  -0.907  -0.858  -0.829
165   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   I         2.058   2.121   2.156   2.099   2.192   2.259   2.210   2.318   2.367
172   S         0.412   0.359   0.302   0.230   0.122   0.078   0.340   0.242   0.147
173   V         0.412   0.359   0.302   0.340   0.245   0.165   0.340   0.242   0.147
174   P        -0.986  -0.964  -0.950  -0.908  -0.865  -0.817  -0.907  -0.858  -0.829
175   Y         0.029   0.321   0.332  -0.002   0.468   0.489  -0.283   0.181   0.196
176   N         0.412   0.321   0.297   0.298   0.213   0.123   0.340   0.180   0.139
177   W         0.412   0.321   0.297   0.611   0.483   0.442   0.340   0.180   0.139
178   T         0.412   0.359   0.302   0.546   0.494   0.421   0.340   0.242   0.147
179   S         0.412   0.321   0.297   0.485   0.293   0.251   0.340   0.180   0.139
180   Q        -0.986  -0.964  -0.950  -0.930  -0.871  -0.870  -0.907  -0.858  -0.829
181   Y         0.412   0.321   0.297   0.655   0.517   0.467   0.340   0.180   0.139
182   S         0.412   0.359   0.302   0.234   0.152   0.085   0.340   0.242   0.147
183   I        -0.986  -0.964  -0.950  -0.979  -0.953  -0.899  -0.907  -0.858  -0.829
184   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   D         0.412   0.321   0.297   0.535   0.342   0.310   0.340   0.180   0.139
186   Y        -0.986  -0.964  -0.950  -0.801  -0.814  -0.801  -0.907  -0.858  -0.829
187   D        -0.986  -0.964  -0.950  -1.101  -1.035  -1.039  -0.907  -0.858  -0.829
188   T         0.412   0.321   0.297   0.382   0.247   0.206   0.340   0.180   0.139
189   D         0.029   0.321   0.332  -0.337   0.159   0.176  -0.283   0.181   0.196
190   A         2.058   2.121   2.156   1.899   2.053   2.070   2.210   2.318   2.367
191   N        -0.986  -0.964  -0.950  -1.120  -1.048  -1.065  -0.907  -0.858  -0.829
192   E        -0.986  -0.964  -0.950  -0.664  -0.655  -0.615  -0.907  -0.858  -0.829
193   D         0.412   0.359   0.302   0.301   0.202   0.140   0.340   0.242   0.147
194   N        -0.986  -0.964  -0.950  -0.899  -0.816  -0.780  -0.907  -0.858  -0.829
195   L        -0.986  -0.964  -0.950  -1.019  -0.979  -0.941  -0.907  -0.858  -0.829
196   D        -0.986  -0.964  -0.950  -1.107  -1.076  -1.048  -0.907  -0.858  -0.829
197   F        -0.986  -0.964  -0.950  -1.085  -1.003  -1.000  -0.907  -0.858  -0.829
198   R        -0.986  -0.964  -0.950  -1.057  -0.943  -0.916  -0.907  -0.858  -0.829
199   F        -0.986  -0.964  -0.950  -0.848  -0.818  -0.796  -0.907  -0.858  -0.829
200   I        -0.986  -0.964  -0.950  -1.016  -0.948  -0.924  -0.907  -0.858  -0.829
201   K        -0.986  -0.964  -0.950  -0.881  -0.922  -0.870  -0.907  -0.858  -0.829
202   S         0.412   0.359   0.302   0.296   0.225   0.177   0.340   0.242   0.147
203   L         0.412   0.321   0.297   0.485   0.325   0.282   0.340   0.180   0.139
204   L         0.412   0.321   0.297   0.213   0.062   0.044   0.340   0.180   0.139
205   D         0.412   0.359   0.302   0.301   0.202   0.140   0.340   0.242   0.147
206   K        -0.986  -0.964  -0.950  -1.076  -1.026  -0.941  -0.907  -0.858  -0.829
207   K         0.412   0.321   0.297   0.357   0.179   0.180   0.340   0.180   0.139
208   N         0.412   0.321   0.297   0.326   0.241   0.148   0.340   0.180   0.139
209   W         0.412   0.359   0.302   0.640   0.558   0.452   0.340   0.242   0.147
210   L         0.412   0.321   0.297   0.319   0.225   0.137   0.340   0.180   0.139
211   K        -0.986  -0.964  -0.950  -1.063  -1.002  -0.987  -0.907  -0.858  -0.829
212   K        -0.986  -0.964  -0.950  -0.884  -0.896  -0.854  -0.907  -0.858  -0.829
213   I         0.412   0.321   0.297   0.620   0.464   0.426   0.340   0.180   0.139
214   N        -0.986  -0.964  -0.950  -0.902  -0.911  -0.878  -0.907  -0.858  -0.829
215   Q         0.412   0.321   0.297   0.717   0.558   0.513   0.340   0.180   0.139
216   T        -0.986  -0.964  -0.950  -1.029  -0.959  -0.979  -0.907  -0.858  -0.829
217   V        -0.986  -0.964  -0.950  -0.985  -0.989  -0.983  -0.907  -0.858  -0.829
218   S        -0.986  -0.964  -0.950  -1.095  -1.038  -1.013  -0.907  -0.858  -0.829
219   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   P         0.412   0.359   0.302   0.578   0.477   0.359   0.340   0.242   0.147
231   Y        -0.986  -0.964  -0.950  -0.675  -0.697  -0.705  -0.907  -0.858  -0.829
232   N        -0.986  -0.964  -0.950  -0.930  -0.875  -0.870  -0.907  -0.858  -0.829
233   V        -0.986  -0.964  -0.950  -0.783  -0.829  -0.805  -0.907  -0.858  -0.829
234   V         0.029   0.321   0.332  -0.343   0.187   0.196  -0.283   0.181   0.196
235   Q         2.058   2.121   2.156   2.113   2.225   2.273   2.210   2.318   2.367
236   L        -0.986  -0.964  -0.950  -0.954  -0.974  -0.941  -0.907  -0.858  -0.829
237   W         2.058   2.121   2.156   2.218   2.320   2.372   2.210   2.318   2.367
238   Y         0.412   0.359   0.302   0.533   0.436   0.333   0.340   0.242   0.147
239   S         0.412   0.321   0.297   0.451   0.278   0.221   0.340   0.180   0.139
240   K         0.412   0.321   0.297   0.515   0.352   0.318   0.340   0.180   0.139
241   D         0.412   0.321   0.297   0.622   0.444   0.386   0.340   0.180   0.139
242   M        -0.986  -0.964  -0.950  -0.768  -0.654  -0.607  -0.907  -0.858  -0.829
243   V        -0.986  -0.964  -0.950  -1.072  -0.994  -0.983  -0.907  -0.858  -0.829
244   W         0.412   0.359   0.302   0.616   0.507   0.416   0.340   0.242   0.147
245   A         2.058   2.121   2.156   1.899   2.053   2.070   2.210   2.318   2.367
246   N        -0.986  -0.964  -0.950  -1.117  -1.056  -1.039  -0.907  -0.858  -0.829
247   V         0.412   0.321   0.297   0.479   0.306   0.272   0.340   0.180   0.139
248   Q         2.058   2.121   2.156   2.113   2.225   2.273   2.210   2.318   2.367
249   R        -0.986  -0.964  -0.950  -0.857  -0.808  -0.764  -0.907  -0.858  -0.829
250   Q         2.058   2.121   2.156   2.113   2.225   2.273   2.210   2.318   2.367
251   Y        -0.986  -0.964  -0.950  -0.957  -0.865  -0.825  -0.907  -0.858  -0.829
252   C         2.058   2.121   2.156   2.294   2.375   2.444   2.210   2.318   2.367
253   S        -0.986  -0.964  -0.950  -0.836  -0.907  -0.878  -0.907  -0.858  -0.829
254   G        -0.986  -0.964  -0.950  -0.798  -0.839  -0.825  -0.907  -0.858  -0.829
255   V         0.412   0.321   0.297   0.553   0.362   0.337   0.340   0.180   0.139
256   Y        -0.986  -0.964  -0.950  -1.025  -0.996  -0.975  -0.907  -0.858  -0.829
257   P        -0.986  -0.964  -0.950  -0.994  -0.960  -0.932  -0.907  -0.858  -0.829
258   G         0.412   0.359   0.302   0.417   0.417   0.292   0.340   0.242   0.147
259   G        -0.986  -0.964  -0.950  -1.041  -1.047  -1.013  -0.907  -0.858  -0.829
260   T        -0.986  -0.964  -0.950  -0.991  -0.940  -0.903  -0.907  -0.858  -0.829
261   Q        -0.986  -0.964  -0.950  -0.918  -0.893  -0.854  -0.907  -0.858  -0.829
262   C         2.058   2.121   2.156   2.294   2.375   2.444   2.210   2.318   2.367
263   S         0.412   0.359   0.302   0.220   0.139   0.064   0.340   0.242   0.147
264   A        -0.986  -0.964  -0.950  -0.905  -0.946  -0.945  -0.907  -0.858  -0.829
265   W         2.058   2.121   2.156   2.218   2.320   2.372   2.210   2.318   2.367
266   S         0.412   0.359   0.302   0.187   0.086   0.013   0.340   0.242   0.147
267   R        -0.986  -0.964  -0.950  -0.979  -0.835  -0.858  -0.907  -0.858  -0.829
268   Y        -0.986  -0.964  -0.950  -0.804  -0.783  -0.792  -0.907  -0.858  -0.829
269   Y        -0.986  -0.964  -0.950  -0.933  -0.861  -0.849  -0.907  -0.858  -0.829
270   H        -0.986  -0.964  -0.950  -0.573  -0.537  -0.520  -0.907  -0.858  -0.829
271   V         0.412   0.359   0.302   0.382   0.297   0.227   0.340   0.242   0.147
272   D        -0.986  -0.964  -0.950  -0.902  -0.843  -0.809  -0.907  -0.858  -0.829
273   A         2.058   2.121   2.156   1.899   2.053   2.070   2.210   2.318   2.367
274   P         2.058   2.121   2.156   2.218   2.296   2.372   2.210   2.318   2.367
275   T         0.412   0.321   0.297   0.382   0.247   0.206   0.340   0.180   0.139
276   C         0.412   0.321   0.297   0.515   0.356   0.375   0.340   0.180   0.139
277   D         0.412   0.321   0.297   0.293   0.186   0.098   0.340   0.180   0.139
278   E        -0.986  -0.964  -0.950  -0.973  -0.857  -0.849  -0.907  -0.858  -0.829
279   P        -0.986  -0.964  -0.950  -1.035  -0.930  -0.928  -0.907  -0.858  -0.829
280   V         0.412   0.321   0.297   0.375   0.231   0.182   0.340   0.180   0.139
281   A         0.412   0.321   0.297   0.317   0.171   0.120   0.340   0.180   0.139
282   S        -0.986  -0.964  -0.950  -0.733  -0.816  -0.784  -0.907  -0.858  -0.829
283   Y        -0.986  -0.964  -0.950  -0.881  -0.795  -0.768  -0.907  -0.858  -0.829
284   M         0.412   0.321   0.297   0.447   0.392   0.329   0.340   0.180   0.139
285   T         0.412   0.321   0.297   0.693   0.519   0.476   0.340   0.180   0.139
286   K         0.412   0.321   0.297   0.230   0.060   0.070   0.340   0.180   0.139
287   M        -0.986  -0.964  -0.950  -1.035  -0.898  -0.887  -0.907  -0.858  -0.829
288   L        -0.986  -0.964  -0.950  -1.066  -0.982  -0.992  -0.907  -0.858  -0.829
289   E         0.412   0.359   0.302   0.535   0.411   0.320   0.340   0.242   0.147
290   N         0.029   0.321   0.332  -0.337   0.211   0.217  -0.283   0.181   0.196
291   E        -0.986  -0.964  -0.950  -0.786  -0.686  -0.654  -0.907  -0.858  -0.829
292   V        -0.986  -0.964  -0.950  -0.927  -0.938  -0.903  -0.907  -0.858  -0.829
293   Q         0.412   0.359   0.302   0.564   0.497   0.402   0.340   0.242   0.147
294   C         2.058   2.121   2.156   2.294   2.375   2.444   2.210   2.318   2.367
295   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   D         2.058   2.121   2.156   1.892   1.993   2.063   2.210   2.318   2.367
314   S         0.412   0.321   0.297   0.241   0.117   0.037   0.340   0.180   0.139
315   D        -0.986  -0.964  -0.950  -0.742  -0.854  -0.796  -0.907  -0.858  -0.829
316   F         0.412   0.359   0.302   0.701   0.628   0.556   0.340   0.242   0.147
317   S         0.412   0.321   0.297   0.234   0.061   0.031   0.340   0.180   0.139
318   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
327   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   S         0.412   0.359   0.302   0.296   0.225   0.177   0.340   0.242   0.147
336   T        -0.986  -0.964  -0.950  -0.754  -0.806  -0.764  -0.907  -0.858  -0.829
337   L         2.058   2.121   2.156   1.971   2.076   2.138   2.210   2.318   2.367
338   K         0.412   0.321   0.297   0.336   0.223   0.162   0.340   0.180   0.139
339   K         0.029   0.321   0.332  -0.154   0.285   0.343  -0.283   0.181   0.196
340   I         0.412   0.359   0.302   0.501   0.388   0.316   0.340   0.242   0.147
341   F         2.058   2.121   2.156   2.197   2.287   2.352   2.210   2.318   2.367
342   S        -0.986  -0.964  -0.950  -0.842  -0.947  -0.887  -0.907  -0.858  -0.829
343   K         0.029   0.321   0.332  -0.242   0.230   0.288  -0.283   0.181   0.196
344   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   S         0.029   0.321   0.332  -0.311   0.120   0.163  -0.283   0.181   0.196
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25577
Output conservation file - output/P25577
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
