1     M         2.080   2.093   2.193   2.288   2.307   2.467   2.346   2.366   2.536
2     S        -0.480  -0.522  -0.549  -0.447  -0.522  -0.554  -0.467  -0.517  -0.538
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     I        -1.612  -1.601  -1.541  -1.551  -1.558  -1.443  -1.170  -1.156  -1.071
5     N        -0.004   0.018   0.011  -0.133  -0.097  -0.123  -0.232  -0.203  -0.203
6     L        -0.480  -0.527  -0.572  -0.634  -0.694  -0.760  -0.467  -0.524  -0.567
7     H         1.152   1.212   1.053   1.420   1.501   1.304   1.174   1.274   0.974
8     S        -0.480  -0.509  -0.545  -0.427  -0.479  -0.523  -0.467  -0.503  -0.534
9     A        -1.136  -1.141  -1.113  -1.079  -1.095  -1.025  -0.935  -0.937  -0.883
10    P        -0.004   0.017   0.007  -0.238  -0.204  -0.195  -0.232  -0.215  -0.213
11    E        -0.660  -0.683  -0.631  -0.645  -0.677  -0.587  -0.701  -0.721  -0.643
12    Y        -1.136  -1.126  -1.118  -0.988  -0.992  -0.943  -0.935  -0.923  -0.888
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    D        -0.480  -0.509  -0.545  -0.431  -0.471  -0.549  -0.467  -0.503  -0.534
19    P        -0.660  -0.624  -0.626  -0.431  -0.371  -0.361  -0.701  -0.661  -0.638
20    S        -0.660  -0.677  -0.641  -0.710  -0.739  -0.673  -0.701  -0.715  -0.654
21    Y         2.080   2.093   2.193   2.243   2.263   2.421   2.346   2.366   2.536
22    K         1.152   1.074   1.021   1.106   1.004   0.935   1.174   1.037   0.914
23    L         1.152   1.180   1.045   0.960   1.000   0.815   1.174   1.220   0.958
24    I        -0.004   0.005   0.002  -0.392  -0.384  -0.374  -0.232  -0.224  -0.220
25    Q         1.152   1.074   1.021   1.342   1.228   1.140   1.174   1.037   0.914
26    L         2.080   2.093   2.193   1.812   1.832   1.983   2.346   2.366   2.536
27    T        -0.660  -0.633  -0.622  -0.635  -0.589  -0.579  -0.701  -0.669  -0.634
28    P        -0.660  -0.684  -0.630  -0.703  -0.743  -0.662  -0.701  -0.722  -0.642
29    E        -1.136  -1.133  -1.099  -1.093  -1.078  -1.041  -0.935  -0.929  -0.869
30    L         0.652   0.663   0.750   0.107   0.130   0.254   0.237   0.254   0.375
31    L         1.152   1.074   1.021   0.924   0.812   0.720   1.174   1.037   0.914
32    D        -0.480  -0.514  -0.548  -0.295  -0.343  -0.380  -0.467  -0.508  -0.537
33    I        -1.136  -1.141  -1.113  -0.901  -0.917  -0.875  -0.935  -0.937  -0.883
34    I        -0.660  -0.633  -0.622  -0.916  -0.887  -0.844  -0.701  -0.669  -0.634
35    Q        -0.660  -0.683  -0.631  -0.696  -0.724  -0.652  -0.701  -0.721  -0.643
36    D        -1.136  -1.126  -1.118  -1.111  -1.103  -1.080  -0.935  -0.923  -0.888
37    P        -1.136  -1.141  -1.113  -0.973  -0.992  -0.954  -0.935  -0.937  -0.883
38    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    H        -0.776  -0.770  -0.696  -0.676  -0.665  -0.551  -0.818  -0.808  -0.710
42    Q        -0.660  -0.624  -0.626  -0.616  -0.576  -0.553  -0.701  -0.661  -0.638
43    L         0.292   0.246   0.144   0.109   0.037  -0.115   0.237   0.165   0.009
44    R        -1.612  -1.601  -1.541  -1.530  -1.523  -1.421  -1.170  -1.156  -1.071
45    F        -0.480  -0.527  -0.572  -0.370  -0.438  -0.559  -0.467  -0.524  -0.567
46    K         2.080   2.093   2.193   1.943   1.962   2.116   2.346   2.366   2.536
47    S         0.292   0.246   0.144   0.311   0.232   0.080   0.237   0.165   0.009
48    L        -0.665  -0.701  -0.651  -0.785  -0.823  -0.732  -0.692  -0.732  -0.660
49    D        -0.665  -0.698  -0.648  -0.767  -0.829  -0.758  -0.692  -0.729  -0.656
50    K        -0.665  -0.619  -0.622  -0.869  -0.790  -0.818  -0.692  -0.635  -0.626
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    D        -0.480  -0.522  -0.549  -0.435  -0.497  -0.559  -0.467  -0.517  -0.538
61    K        -0.480  -0.438  -0.521  -0.479  -0.418  -0.532  -0.467  -0.412  -0.505
62    S        -0.660  -0.677  -0.641  -0.667  -0.691  -0.626  -0.701  -0.715  -0.654
63    E        -1.136  -1.152  -1.119  -0.966  -0.978  -0.920  -0.935  -0.948  -0.888
64    V        -0.004  -0.016  -0.011  -0.237  -0.281  -0.295  -0.232  -0.253  -0.238
65    V         1.152   1.172   1.048   1.330   1.358   1.199   1.174   1.206   0.965
66    L         2.080   2.093   2.193   1.812   1.832   1.983   2.346   2.366   2.536
67    C         1.152   1.160   1.050   1.493   1.506   1.354   1.174   1.186   0.967
68    S        -0.004  -0.052  -0.012  -0.125  -0.188  -0.124  -0.232  -0.291  -0.236
69    H        -1.136  -1.126  -1.118  -1.104  -1.107  -1.085  -0.935  -0.923  -0.888
70    D        -0.004   0.031   0.029  -0.076  -0.011  -0.025  -0.232  -0.177  -0.177
71    K        -0.480  -0.514  -0.548  -0.493  -0.542  -0.588  -0.467  -0.508  -0.537
72    T         2.080   2.093   2.193   2.155   2.173   2.332   2.346   2.366   2.536
73    W         1.152   1.172   1.048   1.507   1.537   1.368   1.174   1.206   0.965
74    V        -0.660  -0.680  -0.643  -0.685  -0.711  -0.637  -0.701  -0.718  -0.655
75    L        -0.480  -0.517  -0.545  -0.608  -0.656  -0.688  -0.467  -0.512  -0.534
76    K         0.768   0.781   0.818   0.545   0.565   0.616   0.471   0.491   0.515
77    Q         2.080   2.093   2.193   2.224   2.243   2.403   2.346   2.366   2.536
78    R        -0.004   0.018   0.011   0.077   0.112   0.092  -0.232  -0.203  -0.203
79    K         0.292   0.268   0.150   0.411   0.370   0.158   0.237   0.196   0.018
80    H         1.152   1.074   1.021   1.486   1.381   1.308   1.174   1.037   0.914
81    S         2.080   2.093   2.193   2.015   2.034   2.190   2.346   2.366   2.536
82    N         2.080   2.093   2.193   2.176   2.195   2.353   2.346   2.366   2.536
83    T         0.292   0.314   0.175   0.488   0.519   0.321   0.237   0.268   0.056
84    V         1.152   1.074   1.021   1.245   1.123   1.016   1.174   1.037   0.914
85    L        -0.480  -0.504  -0.553  -0.552  -0.572  -0.628  -0.467  -0.496  -0.544
86    L         1.152   1.180   1.045   0.960   1.000   0.815   1.174   1.220   0.958
87    M        -0.004  -0.052  -0.012  -0.084  -0.157  -0.114  -0.232  -0.291  -0.236
88    R        -0.480  -0.487  -0.548  -0.343  -0.363  -0.470  -0.467  -0.475  -0.538
89    E        -0.062  -0.093  -0.046  -0.148  -0.199  -0.122  -0.291  -0.338  -0.277
90    F        -0.062  -0.093  -0.046  -0.040  -0.082  -0.026  -0.291  -0.338  -0.277
91    V        -0.776  -0.763  -0.696  -0.823  -0.816  -0.701  -0.818  -0.800  -0.710
92    P        -0.062  -0.093  -0.046  -0.152  -0.220  -0.161  -0.291  -0.338  -0.277
93    E        -0.776  -0.763  -0.696  -0.871  -0.843  -0.750  -0.818  -0.800  -0.710
94    Q        -0.776  -0.763  -0.696  -0.782  -0.785  -0.660  -0.818  -0.800  -0.710
95    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    T        -0.062  -0.017  -0.017  -0.203  -0.119  -0.154  -0.291  -0.223  -0.234
98    F        -0.665  -0.682  -0.642  -0.775  -0.807  -0.749  -0.692  -0.711  -0.650
99    D         1.049   1.020   0.976   1.079   1.037   0.969   0.996   0.940   0.828
100   E        -0.094  -0.125  -0.043  -0.433  -0.479  -0.359  -0.354  -0.390  -0.279
101   T        -0.062  -0.071  -0.025  -0.118  -0.130  -0.075  -0.291  -0.305  -0.245
102   L         0.921   0.962   0.921   0.646   0.707   0.639   0.764   0.834   0.721
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   S        -0.776  -0.769  -0.696  -0.999  -0.988  -0.880  -0.818  -0.807  -0.710
110   K        -0.062  -0.040  -0.042  -0.224  -0.186  -0.207  -0.291  -0.259  -0.271
111   P         2.080   2.093   2.193   2.173   2.193   2.351   2.346   2.366   2.536
112   Y        -0.776  -0.769  -0.696  -0.693  -0.682  -0.569  -0.818  -0.807  -0.710
113   M        -0.665  -0.628  -0.648  -0.525  -0.473  -0.497  -0.692  -0.646  -0.656
114   D        -1.136  -1.155  -1.122  -1.053  -1.071  -1.032  -0.935  -0.950  -0.891
115   V        -1.136  -1.126  -1.118  -1.147  -1.143  -1.084  -0.935  -0.923  -0.888
116   V        -1.136  -1.089  -1.099  -1.059  -1.000  -0.994  -0.935  -0.885  -0.869
117   G         0.292   0.240   0.141   0.565   0.497   0.341   0.237   0.157   0.004
118   F        -0.004  -0.005   0.002  -0.158  -0.174  -0.188  -0.232  -0.241  -0.220
119   A        -1.136  -1.144  -1.104  -0.875  -0.888  -0.829  -0.935  -0.940  -0.874
120   K        -1.136  -1.149  -1.103  -1.089  -1.095  -1.025  -0.935  -0.945  -0.873
121   T        -0.004  -0.049   0.004  -0.193  -0.252  -0.197  -0.232  -0.286  -0.217
122   E        -1.612  -1.601  -1.541  -1.518  -1.506  -1.409  -1.170  -1.156  -1.071
123   S        -0.004  -0.036   0.006  -0.111  -0.160  -0.124  -0.232  -0.264  -0.210
124   E         2.080   2.093   2.193   2.029   2.046   2.204   2.346   2.366   2.536
125   F        -0.480  -0.482  -0.545  -0.236  -0.227  -0.350  -0.467  -0.470  -0.534
126   E         1.152   1.074   1.021   1.173   1.064   0.989   1.174   1.037   0.914
127   T         0.292   0.365   0.175   0.150   0.253  -0.011   0.237   0.344   0.056
128   R        -0.184  -0.172  -0.094  -0.317  -0.308  -0.189  -0.467  -0.449  -0.346
129   E        -0.004   0.024   0.018  -0.341  -0.293  -0.336  -0.232  -0.193  -0.198
130   T        -0.660  -0.666  -0.638  -0.733  -0.754  -0.696  -0.701  -0.705  -0.651
131   H        -0.480  -0.415  -0.512  -0.283  -0.184  -0.338  -0.467  -0.383  -0.493
132   G         2.080   2.093   2.193   2.240   2.260   2.418   2.346   2.366   2.536
133   E        -0.480  -0.500  -0.540  -0.406  -0.429  -0.488  -0.467  -0.492  -0.527
134   L         0.652   0.662   0.748   0.107   0.118   0.244   0.237   0.251   0.372
135   N        -0.004   0.021   0.024  -0.099  -0.058  -0.056  -0.232  -0.192  -0.184
136   L        -1.136  -1.089  -1.099  -1.082  -0.996  -1.037  -0.935  -0.885  -0.869
137   N        -1.136  -1.089  -1.099  -0.928  -0.865  -0.853  -0.935  -0.885  -0.869
138   S        -1.136  -1.089  -1.099  -1.141  -1.060  -1.093  -0.935  -0.885  -0.869
139   V        -0.004   0.046   0.024  -0.392  -0.323  -0.343  -0.232  -0.165  -0.188
140   P         1.152   1.186   1.046   1.323   1.373   1.168   1.174   1.231   0.959
141   I        -0.480  -0.522  -0.549  -0.472  -0.522  -0.581  -0.467  -0.517  -0.538
142   Y         1.152   1.172   1.048   1.393   1.424   1.255   1.174   1.206   0.965
143   N        -0.004   0.037   0.024  -0.014   0.047   0.047  -0.232  -0.172  -0.188
144   G         2.080   2.093   2.193   2.235   2.254   2.413   2.346   2.366   2.536
145   E        -1.136  -1.152  -1.119  -1.105  -1.130  -1.077  -0.935  -0.948  -0.888
146   L        -0.776  -0.764  -0.696  -1.017  -0.980  -0.899  -0.818  -0.802  -0.710
147   D        -0.776  -0.764  -0.696  -0.970  -0.959  -0.851  -0.818  -0.802  -0.710
148   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   K        -0.660  -0.625  -0.617  -0.720  -0.661  -0.655  -0.701  -0.663  -0.629
152   I        -0.660  -0.684  -0.630  -0.866  -0.884  -0.789  -0.701  -0.722  -0.642
153   M        -1.612  -1.601  -1.541  -1.403  -1.403  -1.292  -1.170  -1.156  -1.071
154   K        -1.612  -1.601  -1.541  -1.349  -1.316  -1.237  -1.170  -1.156  -1.071
155   R        -0.480  -0.434  -0.526  -0.486  -0.419  -0.547  -0.467  -0.407  -0.511
156   S        -1.612  -1.601  -1.541  -1.497  -1.447  -1.388  -1.170  -1.156  -1.071
157   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   T        -0.004  -0.016  -0.011  -0.050  -0.078  -0.064  -0.232  -0.253  -0.238
164   L         0.292   0.314   0.175   0.154   0.187  -0.005   0.237   0.268   0.056
165   E        -1.136  -1.144  -1.104  -1.178  -1.194  -1.136  -0.935  -0.940  -0.874
166   E        -0.004  -0.052  -0.012  -0.104  -0.177  -0.115  -0.232  -0.291  -0.236
167   L         1.152   1.186   1.046   0.966   1.016   0.826   1.174   1.231   0.959
168   L        -1.136  -1.152  -1.119  -1.248  -1.246  -1.197  -0.935  -0.948  -0.888
169   E        -0.660  -0.621  -0.620  -0.635  -0.574  -0.566  -0.701  -0.657  -0.632
170   N        -0.480  -0.517  -0.545  -0.224  -0.278  -0.314  -0.467  -0.512  -0.534
171   S         1.152   1.186   1.046   1.200   1.246   1.077   1.174   1.231   0.959
172   P        -0.480  -0.514  -0.548  -0.319  -0.381  -0.445  -0.467  -0.508  -0.537
173   C         0.292   0.223   0.144   0.658   0.558   0.424   0.237   0.133   0.008
174   S         2.080   2.093   2.193   2.015   2.034   2.190   2.346   2.366   2.536
175   A        -1.612  -1.601  -1.541  -1.174  -1.153  -1.059  -1.170  -1.156  -1.071
176   L        -1.136  -1.130  -1.100  -1.219  -1.193  -1.174  -0.935  -0.927  -0.870
177   E         1.152   1.074   1.021   1.187   1.081   1.012   1.174   1.037   0.914
178   G         0.292   0.360   0.174   0.557   0.655   0.397   0.237   0.336   0.054
179   I        -1.612  -1.601  -1.541  -1.482  -1.463  -1.373  -1.170  -1.156  -1.071
180   S        -0.480  -0.522  -0.549  -0.397  -0.457  -0.490  -0.467  -0.517  -0.538
181   K        -0.660  -0.683  -0.631  -0.811  -0.834  -0.746  -0.701  -0.721  -0.643
182   W         2.080   2.093   2.193   2.358   2.378   2.539   2.346   2.366   2.536
183   H        -0.660  -0.677  -0.641  -0.371  -0.390  -0.329  -0.701  -0.715  -0.654
184   K        -1.136  -1.138  -1.102  -1.114  -1.104  -1.063  -0.935  -0.934  -0.872
185   I        -0.004   0.022   0.012  -0.336  -0.298  -0.309  -0.232  -0.197  -0.202
186   G         1.152   1.160   1.050   1.415   1.428   1.296   1.174   1.186   0.967
187   G         2.080   2.093   2.193   2.235   2.254   2.413   2.346   2.366   2.536
188   S        -0.004  -0.036   0.006   0.077   0.044   0.094  -0.232  -0.264  -0.210
189   V        -0.004   0.037   0.008  -0.156  -0.092  -0.141  -0.232  -0.170  -0.207
190   K        -0.660  -0.622  -0.626  -0.880  -0.813  -0.845  -0.701  -0.660  -0.638
191   D        -0.004   0.024   0.018  -0.127  -0.086  -0.089  -0.232  -0.193  -0.198
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   G         1.152   1.172   1.048   1.381   1.410   1.241   1.174   1.206   0.965
194   V        -1.136  -1.109  -1.097  -0.944  -0.901  -0.885  -0.935  -0.904  -0.868
195   L         0.292   0.360   0.174   0.451   0.558   0.226   0.237   0.336   0.054
196   C         0.292   0.307   0.156   0.685   0.707   0.485   0.237   0.258   0.028
197   I        -0.480  -0.504  -0.553  -0.601  -0.635  -0.757  -0.467  -0.496  -0.544
198   L         1.152   1.172   1.048   0.985   1.015   0.861   1.174   1.206   0.965
199   S         1.152   1.074   1.021   1.179   1.076   1.008   1.174   1.037   0.914
200   Q        -1.136  -1.093  -1.095  -1.053  -0.991  -0.991  -0.935  -0.889  -0.865
201   D        -1.136  -1.149  -1.103  -1.141  -1.171  -1.102  -0.935  -0.945  -0.873
202   F         0.292   0.234   0.143   0.398   0.297   0.115   0.237   0.148   0.007
203   L         0.292   0.365   0.175   0.275   0.384   0.086   0.237   0.344   0.056
204   F        -0.480  -0.482  -0.545  -0.443  -0.456  -0.588  -0.467  -0.470  -0.534
205   K        -0.660  -0.643  -0.630  -0.817  -0.789  -0.752  -0.701  -0.679  -0.642
206   A        -0.480  -0.527  -0.572  -0.277  -0.353  -0.454  -0.467  -0.524  -0.567
207   L         1.152   1.074   1.021   0.924   0.812   0.720   1.174   1.037   0.914
208   H        -0.660  -0.647  -0.628  -0.468  -0.457  -0.411  -0.701  -0.683  -0.639
209   V        -0.660  -0.666  -0.638  -0.961  -0.974  -0.911  -0.701  -0.705  -0.651
210   L        -0.004   0.000  -0.000  -0.397  -0.396  -0.383  -0.232  -0.233  -0.224
211   L         0.768   0.781   0.818   0.306   0.326   0.360   0.471   0.491   0.515
212   M        -1.136  -1.089  -1.099  -0.916  -0.847  -0.855  -0.935  -0.885  -0.869
213   S         0.292   0.307   0.156   0.248   0.270   0.009   0.237   0.258   0.028
214   A        -0.480  -0.409  -0.542  -0.558  -0.462  -0.622  -0.467  -0.376  -0.530
215   M         0.292   0.223   0.144   0.589   0.488   0.354   0.237   0.133   0.008
216   A        -0.004  -0.016  -0.011  -0.011  -0.045  -0.040  -0.232  -0.253  -0.238
217   E        -0.665  -0.701  -0.651  -0.777  -0.830  -0.765  -0.692  -0.732  -0.660
218   S        -0.665  -0.698  -0.648  -0.781  -0.851  -0.768  -0.692  -0.729  -0.656
219   L         0.292   0.223   0.144   0.117   0.023  -0.104   0.237   0.133   0.008
220   D         0.768   0.745   0.791   0.661   0.617   0.681   0.471   0.418   0.461
221   L        -0.660  -0.646  -0.620  -0.733  -0.721  -0.654  -0.701  -0.683  -0.632
222   Q        -1.612  -1.601  -1.541  -1.397  -1.377  -1.286  -1.170  -1.156  -1.071
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   H        -1.136  -1.152  -1.119  -1.013  -1.065  -1.029  -0.935  -0.948  -0.888
228   L        -0.480  -0.527  -0.572  -0.639  -0.703  -0.766  -0.467  -0.524  -0.567
229   N        -0.004   0.029   0.021  -0.140  -0.089  -0.099  -0.232  -0.184  -0.192
230   V        -1.136  -1.133  -1.099  -1.124  -1.110  -1.066  -0.935  -0.929  -0.869
231   E        -0.184  -0.172  -0.096  -0.499  -0.482  -0.371  -0.467  -0.450  -0.348
232   D         0.292   0.337   0.164   0.320   0.388   0.096   0.237   0.303   0.039
233   T         0.292   0.342   0.185   0.450   0.521   0.279   0.237   0.309   0.071
234   H        -1.136  -1.126  -1.118  -1.056  -1.043  -1.017  -0.935  -0.923  -0.888
235   H        -0.660  -0.618  -0.620  -0.794  -0.742  -0.717  -0.701  -0.656  -0.632
236   A        -1.612  -1.601  -1.541  -1.511  -1.503  -1.402  -1.170  -1.156  -1.071
237   V        -1.136  -1.152  -1.119  -1.058  -1.078  -1.049  -0.935  -0.948  -0.888
238   G        -1.136  -1.130  -1.100  -0.846  -0.851  -0.790  -0.935  -0.927  -0.870
239   K        -0.004  -0.016  -0.011  -0.149  -0.162  -0.133  -0.232  -0.253  -0.238
240   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   E        -0.062  -0.093  -0.046  -0.250  -0.296  -0.242  -0.291  -0.338  -0.277
246   F        -0.776  -0.763  -0.696  -0.755  -0.732  -0.632  -0.818  -0.800  -0.710
247   N         0.921   0.859   0.876   0.997   0.890   0.913   0.764   0.641   0.633
248   P         0.693   0.700   0.764   0.388   0.395   0.455   0.321   0.329   0.404
249   Y         1.049   1.060   0.964   1.233   1.248   1.100   0.996   1.012   0.804
250   T         1.049   1.028   0.965   1.158   1.127   1.026   0.996   0.956   0.807
251   R        -1.236  -1.229  -1.161  -1.044  -1.033  -0.927  -1.029  -1.017  -0.927
252   E        -0.480  -0.514  -0.548  -0.404  -0.450  -0.502  -0.467  -0.508  -0.537
253   I        -0.004   0.031   0.029  -0.050   0.014   0.021  -0.232  -0.177  -0.177
254   I        -0.660  -0.648  -0.626  -0.803  -0.775  -0.755  -0.701  -0.684  -0.638
255   E        -0.004   0.021   0.024  -0.128  -0.080  -0.087  -0.232  -0.192  -0.184
256   T         0.292   0.234   0.143   0.464   0.381   0.234   0.237   0.148   0.007
257   V         0.652   0.662   0.748   0.373   0.387   0.518   0.237   0.251   0.372
258   L         0.768   0.793   0.810   0.306   0.347   0.344   0.471   0.514   0.498
259   N        -0.004  -0.052  -0.012   0.045  -0.031   0.024  -0.232  -0.291  -0.236
260   K         1.152   1.074   1.021   1.115   1.015   0.950   1.174   1.037   0.914
261   F         2.080   2.093   2.193   2.198   2.221   2.375   2.346   2.366   2.536
262   A        -0.184  -0.175  -0.095  -0.069  -0.055   0.067  -0.467  -0.454  -0.347
263   V        -0.480  -0.424  -0.517  -0.318  -0.232  -0.380  -0.467  -0.394  -0.499
264   Q        -0.660  -0.684  -0.629  -0.738  -0.772  -0.698  -0.701  -0.721  -0.641
265   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
269   E         0.292   0.223   0.144   0.407   0.310   0.212   0.237   0.133   0.008
270   Q        -1.612  -1.601  -1.541  -1.446  -1.438  -1.336  -1.170  -1.156  -1.071
271   E         1.152   1.180   1.045   1.158   1.197   1.002   1.174   1.220   0.958
272   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   N        -0.776  -0.763  -0.696  -0.716  -0.703  -0.592  -0.818  -0.800  -0.710
276   T        -1.136  -1.135  -1.100  -0.989  -0.981  -0.913  -0.935  -0.932  -0.870
277   W        -0.184  -0.172  -0.095  -0.090  -0.072   0.043  -0.467  -0.450  -0.347
278   R        -1.136  -1.155  -1.122  -0.837  -0.868  -0.816  -0.935  -0.950  -0.891
279   L         0.768   0.797   0.816   0.306   0.353   0.355   0.471   0.521   0.510
280   R        -0.004   0.021   0.002  -0.012   0.008  -0.001  -0.232  -0.209  -0.220
281   I        -1.612  -1.601  -1.541  -1.633  -1.636  -1.526  -1.170  -1.156  -1.071
282   P        -1.136  -1.126  -1.118  -1.294  -1.265  -1.249  -0.935  -0.923  -0.888
283   F        -1.612  -1.601  -1.541  -1.388  -1.346  -1.277  -1.170  -1.156  -1.071
284   I         1.152   1.160   1.050   1.148   1.158   1.010   1.174   1.186   0.967
285   A        -0.004  -0.048   0.002   0.023  -0.047   0.019  -0.232  -0.284  -0.219
286   Q        -1.136  -1.149  -1.103  -0.940  -0.974  -0.897  -0.935  -0.945  -0.873
287   W         2.080   2.093   2.193   2.358   2.378   2.539   2.346   2.366   2.536
288   Y        -0.004  -0.052  -0.012   0.040  -0.035   0.015  -0.232  -0.291  -0.236
289   G         2.080   2.093   2.193   2.235   2.254   2.413   2.346   2.366   2.536
290   I        -0.480  -0.504  -0.553  -0.601  -0.652  -0.757  -0.467  -0.496  -0.544
291   Q        -1.136  -1.144  -1.104  -0.964  -0.974  -0.925  -0.935  -0.940  -0.874
292   A        -0.004   0.014   0.009   0.031   0.060   0.041  -0.232  -0.206  -0.210
293   L         1.152   1.172   1.048   0.985   1.015   0.861   1.174   1.206   0.965
294   R        -1.136  -1.141  -1.113  -1.064  -1.062  -1.009  -0.935  -0.937  -0.883
295   K         0.292   0.223   0.144   0.200   0.094  -0.048   0.237   0.133   0.008
296   Y        -0.665  -0.662  -0.642  -0.583  -0.584  -0.556  -0.692  -0.686  -0.650
297   V        -0.094  -0.062  -0.050  -0.061  -0.016   0.012  -0.354  -0.314  -0.289
298   S        -0.665  -0.651  -0.627  -0.423  -0.390  -0.363  -0.692  -0.673  -0.631
299   G        -0.094  -0.096  -0.045  -0.242  -0.249  -0.170  -0.354  -0.354  -0.281
300   I        -0.665  -0.678  -0.648  -0.837  -0.860  -0.826  -0.692  -0.704  -0.656
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   S         0.921   0.987   0.917   0.968   1.075   0.936   0.764   0.880   0.713
308   M        -1.136  -1.133  -1.099  -1.126  -1.121  -1.067  -0.935  -0.929  -0.869
309   P        -1.136  -1.133  -1.099  -1.015  -1.005  -0.949  -0.935  -0.929  -0.869
310   I        -0.480  -0.447  -0.521  -0.434  -0.385  -0.492  -0.467  -0.422  -0.505
311   D        -0.660  -0.647  -0.628  -0.852  -0.834  -0.815  -0.701  -0.683  -0.639
312   E         0.292   0.223   0.144   0.351   0.253   0.132   0.237   0.133   0.008
313   F         2.080   2.093   2.193   2.198   2.221   2.375   2.346   2.366   2.536
314   L         0.768   0.750   0.788   0.447   0.422   0.485   0.471   0.429   0.455
315   I         0.768   0.781   0.818   0.396   0.414   0.432   0.471   0.491   0.515
316   K        -0.480  -0.509  -0.545  -0.412  -0.446  -0.481  -0.467  -0.503  -0.534
317   W         2.080   2.093   2.193   2.358   2.378   2.539   2.346   2.366   2.536
318   K         2.080   2.093   2.193   1.943   1.962   2.116   2.346   2.366   2.536
319   S        -0.480  -0.509  -0.545  -0.384  -0.427  -0.469  -0.467  -0.503  -0.534
320   L        -0.004   0.051   0.006  -0.187  -0.100  -0.188  -0.232  -0.157  -0.211
321   F        -0.480  -0.514  -0.548  -0.356  -0.416  -0.494  -0.467  -0.508  -0.537
322   P         2.080   2.093   2.193   2.195   2.214   2.373   2.346   2.366   2.536
323   P         0.292   0.234   0.143   0.512   0.431   0.284   0.237   0.148   0.007
324   F        -0.004  -0.044  -0.000   0.028  -0.031   0.027  -0.232  -0.278  -0.220
325   F         0.768   0.781   0.818   0.775   0.799   0.840   0.471   0.491   0.515
326   P        -0.660  -0.677  -0.641  -0.514  -0.543  -0.469  -0.701  -0.715  -0.654
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   C        -1.136  -1.155  -1.122  -0.839  -0.879  -0.838  -0.935  -0.950  -0.891
329   D        -0.004  -0.052  -0.012  -0.016  -0.074  -0.004  -0.232  -0.291  -0.236
330   I        -0.004  -0.043   0.007  -0.392  -0.438  -0.367  -0.232  -0.276  -0.212
331   D         1.152   1.074   1.021   1.197   1.083   0.995   1.174   1.037   0.914
332   I         0.768   0.741   0.790   0.396   0.325   0.366   0.471   0.410   0.459
333   D        -0.660  -0.634  -0.628  -0.635  -0.604  -0.555  -0.701  -0.672  -0.640
334   M        -0.660  -0.680  -0.643  -0.606  -0.657  -0.610  -0.701  -0.718  -0.655
335   L         0.292   0.223   0.144   0.135   0.031  -0.079   0.237   0.133   0.008
336   R         0.292   0.234   0.143   0.535   0.437   0.294   0.237   0.148   0.007
337   G         2.080   2.093   2.193   2.235   2.254   2.413   2.346   2.366   2.536
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   Y         2.080   2.093   2.193   2.243   2.263   2.421   2.346   2.366   2.536
340   H        -0.480  -0.482  -0.545  -0.116  -0.120  -0.199  -0.467  -0.470  -0.534
341   F        -0.660  -0.619  -0.626  -0.662  -0.619  -0.615  -0.701  -0.656  -0.638
342   K        -0.665  -0.651  -0.627  -0.665  -0.635  -0.629  -0.692  -0.673  -0.631
343   P         1.049   1.060   0.964   1.213   1.231   1.089   0.996   1.012   0.804
344   T        -1.136  -1.133  -1.099  -1.104  -1.082  -1.023  -0.935  -0.929  -0.869
345   D        -0.660  -0.630  -0.627  -0.693  -0.655  -0.638  -0.701  -0.667  -0.639
346   K        -1.136  -1.138  -1.102  -1.074  -1.071  -1.038  -0.935  -0.934  -0.872
347   T        -1.136  -1.138  -1.102  -1.063  -1.051  -0.996  -0.935  -0.934  -0.872
348   V         1.152   1.212   1.053   1.148   1.227   1.016   1.174   1.274   0.974
349   Q        -0.660  -0.636  -0.619  -0.504  -0.461  -0.446  -0.701  -0.673  -0.631
350   Y         0.292   0.223   0.144   0.519   0.409   0.274   0.237   0.133   0.008
351   I        -0.660  -0.635  -0.628  -0.881  -0.859  -0.813  -0.701  -0.671  -0.640
352   A        -0.660  -0.631  -0.618  -0.694  -0.660  -0.616  -0.701  -0.668  -0.629
353   K        -0.660  -0.677  -0.641  -0.717  -0.741  -0.677  -0.701  -0.715  -0.654
354   S        -0.480  -0.438  -0.521  -0.523  -0.455  -0.605  -0.467  -0.412  -0.505
355   T        -0.004  -0.048   0.002  -0.113  -0.176  -0.116  -0.232  -0.284  -0.219
356   L         2.080   2.093   2.193   1.812   1.832   1.983   2.346   2.366   2.536
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   P         0.768   0.793   0.810   0.670   0.714   0.701   0.471   0.514   0.498
359   M        -1.136  -1.130  -1.100  -0.957  -0.941  -0.910  -0.935  -0.927  -0.870
360   D         1.152   1.172   1.048   1.229   1.257   1.090   1.174   1.206   0.965
361   P        -1.136  -1.109  -1.097  -0.997  -0.949  -0.946  -0.935  -0.904  -0.868
362   K         0.768   0.781   0.818   0.435   0.456   0.488   0.471   0.491   0.515
363   E        -0.004   0.009   0.009  -0.123  -0.104  -0.103  -0.232  -0.211  -0.210
364   R         2.080   2.093   2.193   2.246   2.265   2.424   2.346   2.366   2.536
365   F         0.292   0.314   0.175   0.438   0.478   0.233   0.237   0.268   0.056
366   K         0.292   0.240   0.141   0.296   0.226   0.089   0.237   0.157   0.004
367   V        -1.136  -1.126  -1.118  -0.925  -0.907  -0.872  -0.935  -0.923  -0.888
368   L         2.080   2.093   2.193   1.812   1.832   1.983   2.346   2.366   2.536
369   F         2.080   2.093   2.193   2.198   2.221   2.375   2.346   2.366   2.536
370   R        -1.136  -1.084  -1.097  -0.900  -0.817  -0.842  -0.935  -0.879  -0.867
371   L        -0.004  -0.000   0.004  -0.332  -0.336  -0.295  -0.232  -0.236  -0.217
372   Q        -0.480  -0.527  -0.572  -0.306  -0.394  -0.484  -0.467  -0.524  -0.567
373   S        -0.004  -0.052  -0.012  -0.275  -0.346  -0.296  -0.232  -0.291  -0.236
374   Q        -1.136  -1.152  -1.119  -1.061  -1.105  -1.064  -0.935  -0.948  -0.888
375   W         2.080   2.093   2.193   2.358   2.378   2.539   2.346   2.366   2.536
376   D        -0.004   0.046   0.024  -0.128  -0.056  -0.083  -0.232  -0.165  -0.188
377   L        -0.660  -0.634  -0.628  -0.720  -0.692  -0.666  -0.701  -0.672  -0.640
378   E        -0.004   0.033   0.021  -0.119  -0.061  -0.072  -0.232  -0.178  -0.192
379   D         0.768   0.812   0.832   0.547   0.620   0.630   0.471   0.550   0.544
380   I        -0.184  -0.175  -0.095  -0.273  -0.265  -0.146  -0.467  -0.454  -0.347
381   K        -1.612  -1.601  -1.541  -1.618  -1.592  -1.511  -1.170  -1.156  -1.071
382   P         2.080   2.093   2.193   2.195   2.214   2.373   2.346   2.366   2.536
383   L        -0.004   0.040   0.007  -0.141  -0.051  -0.118  -0.232  -0.168  -0.208
384   I         1.152   1.180   1.045   1.173   1.209   1.041   1.174   1.220   0.958
385   E        -0.480  -0.438  -0.521  -0.492  -0.426  -0.570  -0.467  -0.412  -0.505
386   E        -0.660  -0.684  -0.630  -0.787  -0.813  -0.740  -0.701  -0.722  -0.642
387   L        -0.004  -0.052  -0.012  -0.323  -0.388  -0.329  -0.232  -0.291  -0.236
388   N        -0.480  -0.527  -0.572  -0.375  -0.464  -0.557  -0.467  -0.524  -0.567
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   S        -1.136  -1.126  -1.118  -0.917  -0.898  -0.893  -0.935  -0.923  -0.888
391   R         0.292   0.353   0.189   0.316   0.398   0.186   0.237   0.325   0.077
392   G        -0.004  -0.044  -0.000   0.026  -0.035   0.022  -0.232  -0.278  -0.220
393   M        -0.660  -0.619  -0.626  -0.805  -0.742  -0.746  -0.701  -0.656  -0.638
394   K         2.080   2.093   2.193   1.943   1.962   2.116   2.346   2.366   2.536
395   I        -1.136  -1.155  -1.122  -1.011  -1.034  -0.968  -0.935  -0.950  -0.891
396   D         0.652   0.664   0.750   0.328   0.344   0.474   0.237   0.255   0.376
397   S         0.292   0.246   0.144   0.344   0.277   0.128   0.237   0.165   0.009
398   F         0.768   0.781   0.818   0.666   0.689   0.714   0.471   0.491   0.515
399   I         0.768   0.741   0.790   0.562   0.508   0.578   0.471   0.410   0.459
400   M        -0.004   0.051   0.006  -0.355  -0.281  -0.317  -0.232  -0.157  -0.211
401   K         2.080   2.093   2.193   1.943   1.962   2.116   2.346   2.366   2.536
402   Y         2.080   2.093   2.193   2.243   2.263   2.421   2.346   2.366   2.536
403   A         1.152   1.172   1.048   1.408   1.436   1.275   1.174   1.206   0.965
404   R         0.652   0.665   0.750   0.389   0.398   0.527   0.237   0.256   0.375
405   R        -0.004   0.037   0.008  -0.183  -0.123  -0.165  -0.232  -0.170  -0.207
406   K         1.152   1.074   1.021   1.106   1.004   0.935   1.174   1.037   0.914
407   R         0.768   0.745   0.791   0.684   0.627   0.664   0.471   0.418   0.461
408   L        -0.004  -0.038   0.003  -0.237  -0.278  -0.245  -0.232  -0.267  -0.214
409   G         1.152   1.180   1.045   1.350   1.391   1.186   1.174   1.220   0.958
410   K        -1.136  -1.144  -1.104  -1.073  -1.072  -1.009  -0.935  -0.940  -0.874
411   K         0.292   0.307   0.156   0.255   0.277   0.052   0.237   0.258   0.028
412   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
413   T        -0.660  -0.622  -0.626  -0.623  -0.564  -0.576  -0.701  -0.660  -0.638
414   V        -0.184  -0.172  -0.095  -0.291  -0.264  -0.155  -0.467  -0.449  -0.347
415   V         0.768   0.788   0.807   0.639   0.670   0.663   0.471   0.503   0.493
416   T        -0.480  -0.409  -0.542  -0.197  -0.081  -0.326  -0.467  -0.376  -0.530
417   S        -1.136  -1.126  -1.118  -0.854  -0.832  -0.822  -0.935  -0.923  -0.888
418   R         1.152   1.074   1.021   1.363   1.249   1.161   1.174   1.037   0.914
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25559
Output conservation file - output/P25559
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
