1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     M         0.825   0.827   0.863   1.002   1.006   1.040   0.866   0.869   0.920
3     S        -1.315  -1.310  -1.096  -1.582  -1.591  -1.245  -1.479  -1.474  -1.184
4     Q        -1.787  -1.810  -1.599  -1.761  -1.788  -1.476  -1.703  -1.718  -1.440
5     V        -1.658  -1.718  -1.595  -1.644  -1.719  -1.513  -1.591  -1.637  -1.436
6     Q        -0.630  -0.502  -1.029  -0.473  -0.319  -0.980  -0.586  -0.429  -1.102
7     E        -1.574  -1.563  -1.589  -1.603  -1.595  -1.631  -1.479  -1.473  -1.430
8     Q        -2.473  -2.378  -2.321  -2.240  -2.106  -2.028  -1.926  -1.852  -1.705
9     H        -2.130  -2.188  -1.994  -1.768  -1.855  -1.601  -1.815  -1.855  -1.597
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    T        -1.632  -1.675  -1.595  -1.502  -1.574  -1.470  -1.517  -1.572  -1.435
27    V        -2.261  -2.135  -2.002  -2.103  -1.900  -1.791  -1.914  -1.802  -1.603
28    P        -2.261  -2.271  -2.008  -2.127  -2.165  -1.827  -1.914  -1.923  -1.608
29    A        -1.804  -1.806  -1.608  -1.782  -1.755  -1.498  -1.715  -1.714  -1.448
30    D        -0.164  -0.035  -0.324  -0.239  -0.063  -0.500  -0.278  -0.084  -0.573
31    L        -2.358  -2.283  -2.011  -2.359  -2.250  -1.862  -1.993  -1.933  -1.609
32    S        -1.809  -1.603  -1.601  -1.875  -1.586  -1.548  -1.707  -1.489  -1.441
33    Q        -1.054  -1.062  -1.073  -1.008  -1.035  -1.115  -1.135  -1.157  -1.156
34    S        -1.809  -1.842  -1.609  -1.811  -1.877  -1.531  -1.707  -1.746  -1.449
35    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    Q        -1.054  -1.038  -1.067  -0.973  -0.950  -1.054  -1.135  -1.128  -1.149
61    E        -1.261  -1.285  -1.088  -1.432  -1.456  -1.152  -1.421  -1.444  -1.175
62    Q        -1.261  -1.163  -1.090  -1.240  -1.086  -0.997  -1.421  -1.302  -1.177
63    A        -1.809  -1.726  -1.599  -1.861  -1.714  -1.580  -1.707  -1.631  -1.439
64    E        -1.809  -1.740  -1.597  -1.766  -1.687  -1.438  -1.707  -1.642  -1.437
65    A        -1.809  -1.750  -1.599  -1.828  -1.745  -1.487  -1.707  -1.655  -1.439
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    Q        -2.240  -2.256  -2.007  -2.184  -2.226  -1.854  -1.906  -1.914  -1.607
69    G        -2.240  -2.127  -1.997  -2.352  -2.193  -1.997  -1.906  -1.817  -1.599
70    E        -2.240  -2.138  -1.997  -2.064  -1.916  -1.719  -1.906  -1.820  -1.599
71    M        -1.457  -1.423  -1.573  -1.111  -1.078  -1.372  -1.322  -1.291  -1.414
72    E        -1.632  -1.681  -1.591  -1.711  -1.796  -1.684  -1.517  -1.578  -1.432
73    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    Y        -0.750  -0.641  -1.038  -0.652  -0.517  -1.040  -0.739  -0.605  -1.112
77    D        -0.525  -0.509  -0.374  -0.813  -0.786  -0.568  -0.884  -0.863  -0.659
78    E        -0.525  -0.487  -0.371  -0.813  -0.738  -0.561  -0.884  -0.823  -0.655
79    A        -2.240  -2.256  -2.007  -2.310  -2.336  -1.955  -1.906  -1.914  -1.607
80    A        -1.065  -1.070  -1.072  -1.301  -1.334  -1.287  -1.176  -1.200  -1.157
81    L        -0.750  -0.914  -1.062  -0.800  -1.045  -1.282  -0.739  -0.957  -1.142
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    G        -1.574  -1.506  -1.582  -1.667  -1.594  -1.626  -1.479  -1.420  -1.425
86    S        -1.231  -1.189  -1.090  -1.542  -1.489  -1.323  -1.368  -1.320  -1.178
87    F        -1.102  -1.099  -1.073  -1.030  -1.018  -1.020  -1.256  -1.237  -1.157
88    V        -2.130  -2.195  -2.003  -2.052  -2.144  -1.846  -1.815  -1.862  -1.604
89    P        -0.287  -0.227  -0.340  -0.248  -0.151  -0.429  -0.474  -0.382  -0.599
90    I        -0.483  -0.493  -0.374  -0.763  -0.803  -0.620  -0.809  -0.835  -0.660
91    E        -0.630  -0.752  -1.053  -0.511  -0.672  -1.108  -0.586  -0.747  -1.132
92    K        -2.130  -2.195  -2.003  -1.884  -1.989  -1.731  -1.815  -1.862  -1.604
93    L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
94    Q        -1.102  -1.099  -1.073  -1.243  -1.233  -1.189  -1.256  -1.237  -1.157
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    V        -0.483  -0.461  -0.369  -0.740  -0.703  -0.579  -0.809  -0.778  -0.650
97    N         0.080  -0.013  -0.315   0.325   0.196  -0.351   0.084  -0.051  -0.557
98    G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
99    I         0.080  -0.013  -0.315   0.172   0.042  -0.478   0.084  -0.051  -0.557
100   T         0.080   0.126  -0.302   0.195   0.243  -0.327   0.084   0.145  -0.533
101   M        -2.130  -2.153  -1.992  -2.006  -2.052  -1.768  -1.815  -1.834  -1.596
102   A        -2.259  -2.234  -1.998  -2.354  -2.316  -1.959  -1.926  -1.903  -1.600
103   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
104   V         0.080   0.153  -0.300   0.198   0.280  -0.366   0.084   0.182  -0.530
105   K        -1.298  -1.373  -1.562  -0.930  -1.040  -1.326  -1.144  -1.237  -1.403
106   K        -0.630  -0.764  -1.042  -0.385  -0.577  -1.065  -0.586  -0.762  -1.117
107   L        -0.287  -0.356  -0.362  -0.494  -0.613  -0.610  -0.474  -0.596  -0.639
108   R        -2.130  -2.195  -2.003  -1.912  -2.012  -1.744  -1.815  -1.862  -1.604
109   E        -0.955  -0.981  -1.068  -1.064  -1.080  -1.239  -1.033  -1.053  -1.151
110   S        -2.130  -2.195  -2.003  -2.108  -2.216  -1.945  -1.815  -1.862  -1.604
111   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
112   L        -1.231  -1.236  -1.097  -1.342  -1.350  -1.079  -1.368  -1.379  -1.186
113   H        -0.955  -1.067  -1.073  -0.626  -0.792  -0.829  -1.033  -1.177  -1.158
114   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
115   A        -1.231  -1.139  -1.073  -1.393  -1.237  -1.176  -1.368  -1.253  -1.156
116   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
117   A        -0.483  -0.423  -0.360  -0.759  -0.643  -0.573  -0.809  -0.711  -0.636
118   V        -0.483  -0.461  -0.369  -0.660  -0.627  -0.491  -0.809  -0.778  -0.650
119   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
120   Y         0.825   0.827   0.863   1.030   1.031   1.065   0.866   0.869   0.920
121   A        -0.483  -0.423  -0.360  -0.772  -0.660  -0.583  -0.809  -0.711  -0.636
122   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
123   R        -0.483  -0.473  -0.371  -0.586  -0.574  -0.431  -0.809  -0.798  -0.654
124   K        -0.483  -0.497  -0.374  -0.586  -0.622  -0.439  -0.809  -0.841  -0.660
125   D        -2.130  -2.159  -2.000  -1.900  -1.940  -1.740  -1.815  -1.839  -1.602
126   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
127   L        -0.955  -0.986  -1.066  -1.041  -1.082  -1.165  -1.033  -1.061  -1.150
128   E        -1.787  -1.819  -1.604  -1.972  -2.016  -1.658  -1.703  -1.727  -1.445
129   I        -0.287  -0.227  -0.340  -0.320  -0.232  -0.438  -0.474  -0.382  -0.599
130   K         0.825   0.827   0.863   0.911   0.915   0.962   0.866   0.869   0.920
131   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
132   I         0.825   0.827   0.863   0.837   0.837   0.899   0.866   0.869   0.920
133   S         0.825   0.827   0.863   0.828   0.832   0.890   0.866   0.869   0.920
134   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
135   A        -1.298  -1.282  -1.567  -1.161  -1.149  -1.497  -1.144  -1.136  -1.408
136   K         0.825   0.827   0.863   0.911   0.915   0.962   0.866   0.869   0.920
137   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
138   D        -0.630  -0.674  -1.045  -0.473  -0.543  -1.168  -0.586  -0.650  -1.122
139   K         0.080   0.146  -0.299   0.275   0.353  -0.296   0.084   0.172  -0.529
140   L        -0.483  -0.476  -0.372  -0.826  -0.821  -0.622  -0.809  -0.804  -0.656
141   L        -0.287  -0.227  -0.340  -0.497  -0.405  -0.579  -0.474  -0.382  -0.599
142   N        -2.130  -2.108  -1.985  -2.142  -2.126  -1.960  -1.815  -1.789  -1.590
143   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
144   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
145   A        -0.546  -0.520  -0.372  -0.912  -0.857  -0.602  -0.921  -0.883  -0.656
146   R        -0.483  -0.423  -0.360  -0.586  -0.481  -0.411  -0.809  -0.711  -0.636
147   L         0.080   0.134  -0.303   0.022   0.088  -0.507   0.084   0.156  -0.535
148   V         0.825   0.827   0.863   0.849   0.855   0.909   0.866   0.869   0.920
149   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
150   M        -0.483  -0.465  -0.365  -0.615  -0.587  -0.473  -0.809  -0.785  -0.644
151   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
152   F         0.825   0.827   0.863   0.975   0.979   1.018   0.866   0.869   0.920
153   V        -0.483  -0.423  -0.360  -0.685  -0.585  -0.493  -0.809  -0.711  -0.636
154   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
155   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
156   A        -1.315  -1.315  -1.098  -1.612  -1.612  -1.254  -1.479  -1.480  -1.187
157   D        -0.546  -0.529  -0.373  -0.857  -0.831  -0.564  -0.921  -0.898  -0.657
158   F        -1.298  -1.448  -1.579  -0.849  -1.056  -1.275  -1.144  -1.317  -1.420
159   H         0.825   0.827   0.863   1.050   1.053   1.083   0.866   0.869   0.920
160   M        -2.259  -2.219  -2.003  -2.112  -2.061  -1.784  -1.926  -1.889  -1.604
161   R         0.080   0.025  -0.303   0.232   0.159  -0.356   0.084   0.003  -0.535
162   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
163   S         0.080   0.122  -0.301   0.208   0.257  -0.315   0.084   0.140  -0.532
164   E         0.080   0.025  -0.303   0.087   0.017  -0.511   0.084   0.003  -0.535
165   L        -0.287  -0.222  -0.337  -0.438  -0.345  -0.485  -0.474  -0.374  -0.594
166   I         0.825   0.827   0.863   0.837   0.837   0.899   0.866   0.869   0.920
167   C        -0.955  -1.067  -1.073  -0.730  -0.919  -0.995  -1.033  -1.177  -1.158
168   L        -0.483  -0.496  -0.374  -0.826  -0.855  -0.623  -0.809  -0.839  -0.660
169   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
170   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
171   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
172   S         0.825   0.827   0.863   0.828   0.832   0.890   0.866   0.869   0.920
173   K         0.080   0.025  -0.303   0.268   0.198  -0.323   0.084   0.003  -0.535
174   N        -0.546  -0.530  -0.375  -0.625  -0.607  -0.364  -0.921  -0.901  -0.661
175   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
176   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
177   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
178   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
179   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
180   G        -0.630  -0.752  -1.053  -0.598  -0.770  -1.214  -0.586  -0.747  -1.132
181   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
182   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
183   V        -0.483  -0.456  -0.372  -0.664  -0.624  -0.499  -0.809  -0.769  -0.657
184   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
185   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
186   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
187   S         0.080   0.025  -0.303   0.165   0.092  -0.449   0.084   0.003  -0.535
188   I         0.080  -0.013  -0.315   0.198   0.075  -0.393   0.084  -0.051  -0.557
189   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
190   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
191   L        -1.574  -1.634  -1.583  -1.606  -1.679  -1.545  -1.479  -1.533  -1.424
192   F         0.825   0.827   0.863   0.975   0.979   1.018   0.866   0.869   0.920
193   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
194   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
195   F         0.825   0.827   0.863   0.975   0.979   1.018   0.866   0.869   0.920
196   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
197   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
198   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
199   K         0.825   0.827   0.863   0.911   0.915   0.962   0.866   0.869   0.920
200   S         0.825   0.827   0.863   0.828   0.832   0.890   0.866   0.869   0.920
201   Q         0.825   0.827   0.863   0.922   0.925   0.972   0.866   0.869   0.920
202   L        -0.287  -0.356  -0.362  -0.494  -0.613  -0.610  -0.474  -0.596  -0.639
203   C         0.825   0.827   0.863   1.052   1.055   1.084   0.866   0.869   0.920
204   H         0.825   0.827   0.863   1.050   1.053   1.083   0.866   0.869   0.920
205   T         0.080   0.146  -0.299   0.172   0.246  -0.392   0.084   0.172  -0.529
206   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
207   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
208   V         0.825   0.827   0.863   0.849   0.855   0.909   0.866   0.869   0.920
209   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
210   C         0.825   0.827   0.863   1.052   1.055   1.084   0.866   0.869   0.920
211   Q         0.825   0.827   0.863   0.922   0.925   0.972   0.866   0.869   0.920
212   I        -0.483  -0.423  -0.360  -0.826  -0.728  -0.607  -0.809  -0.711  -0.636
213   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
214   L        -1.102  -1.126  -1.079  -1.272  -1.274  -1.157  -1.256  -1.266  -1.164
215   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
216   I        -1.298  -1.228  -1.559  -0.910  -0.822  -1.398  -1.144  -1.074  -1.400
217   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
218   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
219   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
220   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
221   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
222   K         0.825   0.827   0.863   0.911   0.915   0.962   0.866   0.869   0.920
223   C         0.825   0.827   0.863   1.052   1.055   1.084   0.866   0.869   0.920
224   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
225   Y         0.825   0.827   0.863   1.030   1.031   1.065   0.866   0.869   0.920
226   I         0.825   0.827   0.863   0.837   0.837   0.899   0.866   0.869   0.920
227   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
228   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
229   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
230   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
231   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
232   F         0.825   0.827   0.863   0.975   0.979   1.018   0.866   0.869   0.920
233   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
234   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
235   V        -1.298  -1.271  -1.560  -1.031  -1.007  -1.442  -1.144  -1.120  -1.401
236   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
237   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
238   V        -0.955  -1.052  -1.073  -0.935  -1.103  -1.108  -1.033  -1.166  -1.158
239   S        -0.955  -1.052  -1.073  -0.972  -1.143  -1.165  -1.033  -1.166  -1.158
240   I        -0.287  -0.356  -0.362  -0.320  -0.444  -0.480  -0.474  -0.596  -0.639
241   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
242   Q        -1.298  -1.448  -1.579  -0.935  -1.148  -1.376  -1.144  -1.317  -1.420
243   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
244   F        -0.483  -0.423  -0.360  -0.432  -0.332  -0.276  -0.809  -0.711  -0.636
245   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
246   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
247   D        -1.102  -1.126  -1.079  -1.071  -1.087  -1.036  -1.256  -1.266  -1.164
248   P        -0.483  -0.514  -0.374  -0.630  -0.724  -0.512  -0.809  -0.871  -0.659
249   D        -1.102  -1.069  -1.076  -1.214  -1.189  -1.110  -1.256  -1.230  -1.162
250   D        -0.483  -0.514  -0.374  -0.715  -0.790  -0.561  -0.809  -0.871  -0.659
251   A        -1.315  -1.261  -1.091  -1.484  -1.397  -1.111  -1.479  -1.417  -1.179
252   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
253   N        -0.483  -0.423  -0.360  -0.590  -0.495  -0.400  -0.809  -0.711  -0.636
254   N         0.825   0.827   0.863   0.987   0.987   1.027   0.866   0.869   0.920
255   V         0.825   0.827   0.863   0.849   0.855   0.909   0.866   0.869   0.920
256   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
257   Y         0.825   0.827   0.863   1.030   1.031   1.065   0.866   0.869   0.920
258   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
259   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
260   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
261   Y         0.080   0.025  -0.303   0.418   0.349  -0.138   0.084   0.003  -0.535
262   N         0.825   0.827   0.863   0.987   0.987   1.027   0.866   0.869   0.920
263   A        -0.287  -0.363  -0.359  -0.474  -0.602  -0.594  -0.474  -0.607  -0.633
264   D        -0.287  -0.227  -0.340  -0.350  -0.253  -0.486  -0.474  -0.382  -0.599
265   H         0.825   0.827   0.863   1.050   1.053   1.083   0.866   0.869   0.920
266   Q         0.825   0.827   0.863   0.922   0.925   0.972   0.866   0.869   0.920
267   L        -0.955  -0.904  -1.058  -0.996  -0.938  -1.066  -1.033  -0.979  -1.139
268   R        -2.130  -2.056  -1.990  -1.878  -1.779  -1.694  -1.815  -1.743  -1.594
269   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
270   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
271   D        -1.315  -1.309  -1.096  -1.350  -1.342  -1.025  -1.479  -1.473  -1.185
272   A        -2.130  -2.111  -2.000  -1.976  -1.950  -1.707  -1.815  -1.805  -1.602
273   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
274   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
275   Q        -1.574  -1.627  -1.591  -1.399  -1.502  -1.496  -1.479  -1.545  -1.433
276   M         0.825   0.827   0.863   1.002   1.006   1.040   0.866   0.869   0.920
277   M         0.825   0.827   0.863   1.002   1.006   1.040   0.866   0.869   0.920
278   S        -1.298  -1.380  -1.570  -1.055  -1.170  -1.478  -1.144  -1.244  -1.411
279   E         0.080   0.025  -0.303   0.119   0.055  -0.412   0.084   0.003  -0.535
280   S         0.080  -0.013  -0.315   0.184   0.063  -0.417   0.084  -0.051  -0.557
281   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
282   F         0.825   0.827   0.863   0.975   0.979   1.018   0.866   0.869   0.920
283   S         0.825   0.827   0.863   0.828   0.832   0.890   0.866   0.869   0.920
284   L        -0.287  -0.287  -0.349  -0.421  -0.422  -0.474  -0.474  -0.480  -0.616
285   I        -0.483  -0.423  -0.360  -0.826  -0.728  -0.607  -0.809  -0.711  -0.636
286   V        -0.483  -0.451  -0.368  -0.664  -0.614  -0.492  -0.809  -0.759  -0.650
287   V         0.825   0.827   0.863   0.849   0.855   0.909   0.866   0.869   0.920
288   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
289   S         0.825   0.827   0.863   0.828   0.832   0.890   0.866   0.869   0.920
290   V        -1.574  -1.610  -1.586  -1.469  -1.517  -1.483  -1.479  -1.505  -1.427
291   M        -0.287  -0.356  -0.362  -0.172  -0.301  -0.385  -0.474  -0.596  -0.639
292   A        -0.483  -0.476  -0.372  -0.810  -0.801  -0.612  -0.809  -0.804  -0.656
293   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
294   Y         0.825   0.827   0.863   1.030   1.031   1.065   0.866   0.869   0.920
295   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
296   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
297   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
298   F        -0.483  -0.465  -0.365  -0.450  -0.427  -0.291  -0.809  -0.785  -0.644
299   S        -0.955  -1.032  -1.065  -1.022  -1.148  -1.260  -1.033  -1.127  -1.148
300   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
301   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
302   G         0.080   0.134  -0.303   0.023   0.089  -0.561   0.084   0.156  -0.535
303   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
304   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
305   S         0.825   0.827   0.863   0.828   0.832   0.890   0.866   0.869   0.920
306   A         0.080  -0.013  -0.315   0.043  -0.073  -0.520   0.084  -0.051  -0.557
307   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
308   Q         0.825   0.827   0.863   0.922   0.925   0.972   0.866   0.869   0.920
309   M        -0.546  -0.528  -0.375  -0.691  -0.675  -0.420  -0.921  -0.897  -0.661
310   H         0.825   0.827   0.863   1.050   1.053   1.083   0.866   0.869   0.920
311   L        -0.483  -0.465  -0.365  -0.820  -0.792  -0.607  -0.809  -0.785  -0.644
312   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
313   K         0.080   0.038  -0.307   0.275   0.224  -0.309   0.084   0.023  -0.542
314   F         0.080   0.134  -0.303   0.361   0.422  -0.188   0.084   0.156  -0.535
315   M         0.825   0.827   0.863   1.002   1.006   1.040   0.866   0.869   0.920
316   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
317   A        -0.955  -0.848  -1.061  -1.003  -0.839  -1.186  -1.033  -0.892  -1.142
318   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
319   Q         0.825   0.827   0.863   0.922   0.925   0.972   0.866   0.869   0.920
320   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
321   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
322   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
323   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
324   Q        -0.483  -0.423  -0.360  -0.703  -0.603  -0.498  -0.809  -0.711  -0.636
325   F         0.825   0.827   0.863   0.975   0.979   1.018   0.866   0.869   0.920
326   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
327   V        -0.483  -0.423  -0.360  -0.664  -0.563  -0.477  -0.809  -0.711  -0.636
328   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
329   V         0.080   0.122  -0.301   0.187   0.241  -0.428   0.084   0.140  -0.532
330   V         0.825   0.827   0.863   0.849   0.855   0.909   0.866   0.869   0.920
331   V        -0.483  -0.423  -0.360  -0.664  -0.563  -0.477  -0.809  -0.711  -0.636
332   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
333   N         0.825   0.827   0.863   0.987   0.987   1.027   0.866   0.869   0.920
334   Q         0.825   0.827   0.863   0.922   0.925   0.972   0.866   0.869   0.920
335   V         0.825   0.827   0.863   0.849   0.855   0.909   0.866   0.869   0.920
336   V         0.825   0.827   0.863   0.849   0.855   0.909   0.866   0.869   0.920
337   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
338   Q         0.825   0.827   0.863   0.922   0.925   0.972   0.866   0.869   0.920
339   V         0.825   0.827   0.863   0.849   0.855   0.909   0.866   0.869   0.920
340   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
341   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
342   G        -0.891  -0.852  -1.068  -0.931  -0.881  -1.194  -0.921  -0.875  -1.150
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   M        -1.658  -1.631  -1.589  -1.674  -1.658  -1.587  -1.591  -1.562  -1.431
346   A        -1.574  -1.547  -1.578  -1.376  -1.343  -1.463  -1.479  -1.455  -1.420
347   F         0.825   0.827   0.863   0.975   0.979   1.018   0.866   0.869   0.920
348   N         0.825   0.827   0.863   0.987   0.987   1.027   0.866   0.869   0.920
349   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
350   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
351   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
352   K         0.825   0.827   0.863   0.911   0.915   0.962   0.866   0.869   0.920
353   K         0.825   0.827   0.863   0.911   0.915   0.962   0.866   0.869   0.920
354   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
355   I         0.825   0.827   0.863   0.837   0.837   0.899   0.866   0.869   0.920
356   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
357   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
358   N         0.825   0.827   0.863   0.987   0.987   1.027   0.866   0.869   0.920
359   I         0.825   0.827   0.863   0.837   0.837   0.899   0.866   0.869   0.920
360   M        -1.658  -1.691  -1.594  -1.570  -1.629  -1.510  -1.591  -1.613  -1.435
361   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
362   H         0.825   0.827   0.863   1.050   1.053   1.083   0.866   0.869   0.920
363   S        -0.287  -0.363  -0.359  -0.381  -0.525  -0.570  -0.474  -0.607  -0.633
364   S         0.825   0.827   0.863   0.828   0.832   0.890   0.866   0.869   0.920
365   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
366   T         0.825   0.827   0.863   0.814   0.813   0.878   0.866   0.869   0.920
367   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
368   L         0.080  -0.013  -0.315   0.021  -0.097  -0.534   0.084  -0.051  -0.557
369   G        -1.102  -1.099  -1.073  -1.253  -1.220  -1.117  -1.256  -1.237  -1.157
370   F        -0.287  -0.356  -0.362  -0.245  -0.381  -0.485  -0.474  -0.596  -0.639
371   K         0.080   0.038  -0.307   0.275   0.224  -0.309   0.084   0.023  -0.542
372   K         0.825   0.827   0.863   0.911   0.915   0.962   0.866   0.869   0.920
373   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
374   K        -0.483  -0.423  -0.360  -0.598  -0.497  -0.416  -0.809  -0.711  -0.636
375   G         0.080   0.134  -0.303   0.023   0.089  -0.561   0.084   0.156  -0.535
376   C        -1.574  -1.524  -1.583  -1.436  -1.372  -1.409  -1.479  -1.419  -1.424
377   Q        -0.287  -0.314  -0.361  -0.249  -0.302  -0.438  -0.474  -0.524  -0.637
378   R         0.825   0.827   0.863   0.876   0.879   0.932   0.866   0.869   0.920
379   L        -0.955  -0.838  -1.062  -0.880  -0.724  -1.074  -1.033  -0.886  -1.144
380   C         0.080  -0.013  -0.315   0.390   0.264  -0.300   0.084  -0.051  -0.557
381   K         0.825   0.827   0.863   0.911   0.915   0.962   0.866   0.869   0.920
382   V        -0.483  -0.423  -0.360  -0.664  -0.563  -0.477  -0.809  -0.711  -0.636
383   V        -0.483  -0.423  -0.360  -0.496  -0.387  -0.342  -0.809  -0.711  -0.636
384   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
385   S         0.825   0.827   0.863   0.828   0.832   0.890   0.866   0.869   0.920
386   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
387   C         0.825   0.827   0.863   1.052   1.055   1.084   0.866   0.869   0.920
388   L         0.825   0.827   0.863   0.662   0.667   0.747   0.866   0.869   0.920
389   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
390   E         0.825   0.827   0.863   0.749   0.757   0.822   0.866   0.869   0.920
391   A        -0.483  -0.423  -0.360  -0.759  -0.643  -0.573  -0.809  -0.711  -0.636
392   E        -0.630  -0.764  -1.042  -0.549  -0.733  -1.187  -0.586  -0.762  -1.117
393   C         0.080   0.038  -0.307   0.390   0.334  -0.281   0.084   0.023  -0.542
394   V        -0.955  -1.026  -1.073  -0.944  -1.055  -1.180  -1.033  -1.118  -1.158
395   F         0.825   0.827   0.863   0.975   0.979   1.018   0.866   0.869   0.920
396   A         0.825   0.827   0.863   0.686   0.693   0.768   0.866   0.869   0.920
397   I         0.825   0.827   0.863   0.837   0.837   0.899   0.866   0.869   0.920
398   Y        -0.955  -1.052  -1.073  -0.648  -0.803  -0.838  -1.033  -1.166  -1.158
399   E         0.080   0.038  -0.307   0.107   0.059  -0.455   0.084   0.023  -0.542
400   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
401   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
402   V        -0.287  -0.269  -0.360  -0.320  -0.299  -0.476  -0.474  -0.450  -0.635
403   G         0.825   0.827   0.863   0.686   0.689   0.768   0.866   0.869   0.920
404   D         0.825   0.827   0.863   0.839   0.844   0.900   0.866   0.869   0.920
405   P         0.825   0.827   0.863   0.972   0.974   1.014   0.866   0.869   0.920
406   R        -1.102  -1.126  -1.079  -1.111  -1.129  -1.063  -1.256  -1.266  -1.164
407   E        -1.916  -1.945  -1.980  -1.705  -1.752  -1.798  -1.591  -1.625  -1.586
408   E        -1.298  -1.372  -1.576  -1.126  -1.232  -1.525  -1.144  -1.234  -1.417
409   D         0.014  -0.050  -0.316   0.115   0.030  -0.397  -0.009  -0.106  -0.558
410   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
411   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
412   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
413   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
414   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
415   E        -1.916  -1.938  -1.985  -1.674  -1.716  -1.755  -1.591  -1.619  -1.590
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25454
Output conservation file - output/P25454
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
