1     M         0.818   0.838   0.876   1.012   1.021   1.075   0.861   0.885   0.936
2     S        -1.020  -1.155  -1.221  -1.000  -1.230  -1.323  -1.033  -1.204  -1.242
3     V        -2.489  -2.394  -2.233  -2.419  -2.310  -2.034  -2.086  -1.962  -1.716
4     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     E        -0.373  -0.224  -0.417  -0.491  -0.258  -0.560  -0.560  -0.320  -0.641
8     I        -1.385  -1.345  -1.241  -1.572  -1.546  -1.355  -1.507  -1.440  -1.266
9     D        -2.005  -1.903  -1.799  -2.053  -1.873  -1.713  -1.867  -1.736  -1.547
10    S        -2.592  -2.446  -2.242  -2.659  -2.402  -2.119  -2.170  -1.997  -1.723
11    D        -2.005  -1.821  -1.787  -2.024  -1.720  -1.711  -1.867  -1.639  -1.536
12    T        -2.005  -1.960  -1.804  -2.161  -2.109  -1.889  -1.867  -1.789  -1.552
13    A        -2.489  -2.398  -2.233  -2.449  -2.307  -2.044  -2.086  -1.965  -1.716
14    K        -2.979  -2.822  -2.595  -2.644  -2.401  -2.106  -2.296  -2.124  -1.834
15    N        -2.000  -1.990  -1.800  -1.988  -1.983  -1.684  -1.875  -1.818  -1.549
16    I        -1.020  -1.128  -1.219  -0.926  -1.086  -1.206  -1.033  -1.174  -1.240
17    L        -1.815  -1.798  -1.788  -1.830  -1.832  -1.826  -1.665  -1.632  -1.537
18    S        -2.000  -1.960  -1.797  -1.995  -1.927  -1.685  -1.875  -1.795  -1.546
19    V        -0.531  -0.424  -0.447  -0.742  -0.556  -0.613  -0.823  -0.638  -0.692
20    D        -0.137  -0.366  -0.420  -0.029  -0.391  -0.522  -0.191  -0.544  -0.647
21    E        -1.020  -1.163  -1.218  -1.017  -1.233  -1.312  -1.033  -1.214  -1.238
22    L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
23    Q        -0.137  -0.366  -0.420   0.021  -0.318  -0.443  -0.191  -0.544  -0.647
24    N        -1.020  -1.163  -1.218  -0.789  -1.056  -1.163  -1.033  -1.214  -1.238
25    Y        -2.000  -1.850  -1.792  -1.622  -1.408  -1.347  -1.875  -1.683  -1.541
26    G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
27    I         0.818   0.838   0.876   0.773   0.801   0.867   0.861   0.885   0.936
28    N        -0.137  -0.366  -0.420   0.046  -0.325  -0.484  -0.191  -0.544  -0.647
29    A        -0.137  -0.366  -0.420  -0.120  -0.446  -0.493  -0.191  -0.544  -0.647
30    S        -1.325  -1.409  -1.242  -1.568  -1.668  -1.398  -1.454  -1.512  -1.268
31    D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
32    L        -0.137  -0.001  -0.388  -0.136   0.053  -0.553  -0.191   0.007  -0.592
33    Q        -2.000  -1.992  -1.800  -1.928  -1.929  -1.617  -1.875  -1.820  -1.548
34    K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
35    L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
36    K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
37    S        -2.489  -2.394  -2.233  -2.513  -2.340  -2.122  -2.086  -1.962  -1.716
38    G        -1.020  -0.779  -1.187  -1.068  -0.726  -1.355  -1.033  -0.711  -1.201
39    G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
40    I        -0.531  -0.578  -0.466  -0.742  -0.839  -0.650  -0.823  -0.901  -0.725
41    Y        -1.325  -1.142  -1.221  -1.048  -0.777  -0.906  -1.454  -1.194  -1.244
42    T        -0.531  -0.457  -0.445  -0.694  -0.559  -0.579  -0.823  -0.694  -0.688
43    V        -0.531  -0.457  -0.445  -0.733  -0.603  -0.606  -0.823  -0.694  -0.688
44    N        -1.815  -1.862  -1.797  -1.581  -1.678  -1.622  -1.665  -1.693  -1.545
45    T        -1.325  -1.409  -1.242  -1.488  -1.633  -1.377  -1.454  -1.512  -1.268
46    V        -0.137  -0.027  -0.393  -0.042   0.104  -0.379  -0.191  -0.029  -0.601
47    L        -1.020  -1.095  -1.215  -0.965  -1.045  -1.172  -1.033  -1.137  -1.235
48    S        -0.137  -0.366  -0.420  -0.091  -0.403  -0.471  -0.191  -0.544  -0.647
49    T        -0.137  -0.366  -0.420  -0.052  -0.399  -0.529  -0.191  -0.544  -0.647
50    T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
51    R        -0.137  -0.366  -0.420  -0.033  -0.371  -0.483  -0.191  -0.544  -0.647
52    R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
53    H        -1.020  -1.108  -1.214  -0.679  -0.833  -0.956  -1.033  -1.151  -1.234
54    L        -0.137  -0.062  -0.394  -0.159  -0.042  -0.485  -0.191  -0.078  -0.602
55    C        -1.815  -1.816  -1.788  -1.531  -1.597  -1.605  -1.665  -1.650  -1.537
56    K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
57    I        -0.137  -0.027  -0.393  -0.115   0.035  -0.515  -0.191  -0.029  -0.601
58    K        -0.137  -0.027  -0.393  -0.031   0.118  -0.434  -0.191  -0.029  -0.601
59    G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
60    L        -0.137  -0.366  -0.420  -0.164  -0.462  -0.533  -0.191  -0.544  -0.647
61    S         0.818   0.838   0.876   0.753   0.787   0.849   0.861   0.885   0.936
62    E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
63    V        -1.020  -1.163  -1.218  -0.979  -1.232  -1.324  -1.033  -1.214  -1.238
64    K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
65    V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
66    E        -0.137  -0.366  -0.420  -0.152  -0.479  -0.564  -0.191  -0.544  -0.647
67    K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
68    I        -0.137  -0.366  -0.420  -0.136  -0.492  -0.617  -0.191  -0.544  -0.647
69    K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
70    E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
71    A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
72    A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
73    G        -1.325  -1.383  -1.235  -1.499  -1.581  -1.322  -1.454  -1.478  -1.260
74    K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
75    I        -1.325  -1.392  -1.235  -1.486  -1.528  -1.286  -1.454  -1.489  -1.260
76    I        -2.489  -2.411  -2.237  -2.258  -2.105  -1.863  -2.086  -1.975  -1.719
77    Q        -2.489  -2.401  -2.234  -2.148  -1.999  -1.768  -2.086  -1.967  -1.717
78    V        -2.489  -2.427  -2.239  -2.403  -2.344  -2.024  -2.086  -1.986  -1.720
79    G        -0.137  -0.366  -0.420  -0.194  -0.505  -0.566  -0.191  -0.544  -0.647
80    F         0.818   0.838   0.876   0.989   1.004   1.055   0.861   0.885   0.936
81    I        -1.815  -1.816  -1.788  -1.830  -1.862  -1.825  -1.665  -1.650  -1.537
82    P        -0.137  -0.366  -0.420   0.163  -0.189  -0.336  -0.191  -0.544  -0.647
83    A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
84    T        -0.137  -0.366  -0.420  -0.000  -0.318  -0.403  -0.191  -0.544  -0.647
85    V        -1.815  -1.842  -1.790  -1.829  -1.903  -1.841  -1.665  -1.674  -1.539
86    Q        -1.020  -1.163  -1.218  -0.856  -1.103  -1.218  -1.033  -1.214  -1.238
87    L        -2.489  -2.369  -2.237  -2.332  -2.211  -1.924  -2.086  -1.943  -1.719
88    D        -1.510  -1.417  -1.246  -1.692  -1.526  -1.262  -1.665  -1.521  -1.272
89    I        -1.325  -1.387  -1.235  -1.527  -1.556  -1.313  -1.454  -1.483  -1.260
90    R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
91    Q        -1.815  -1.862  -1.797  -1.644  -1.740  -1.667  -1.665  -1.693  -1.545
92    R        -1.325  -1.172  -1.221  -1.416  -1.169  -1.255  -1.454  -1.237  -1.244
93    V        -0.137  -0.062  -0.394  -0.111  -0.001  -0.532  -0.191  -0.078  -0.602
94    Y        -2.489  -2.369  -2.237  -1.989  -1.808  -1.645  -2.086  -1.943  -1.719
95    S        -1.020  -0.910  -1.198  -0.912  -0.752  -1.130  -1.033  -0.875  -1.214
96    L        -0.531  -0.424  -0.447  -0.791  -0.594  -0.672  -0.823  -0.638  -0.692
97    S        -0.137  -0.072  -0.391  -0.125  -0.027  -0.502  -0.191  -0.093  -0.596
98    T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
99    G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
100   S         0.818   0.838   0.876   0.753   0.787   0.849   0.861   0.885   0.936
101   K        -0.137  -0.366  -0.420  -0.055  -0.412  -0.542  -0.191  -0.544  -0.647
102   Q        -0.137  -0.366  -0.420  -0.002  -0.364  -0.501  -0.191  -0.544  -0.647
103   L        -0.531  -0.441  -0.447  -0.731  -0.576  -0.569  -0.823  -0.667  -0.692
104   D        -0.137  -0.366  -0.420   0.018  -0.311  -0.407  -0.191  -0.544  -0.647
105   S        -1.815  -1.862  -1.797  -1.841  -1.963  -1.841  -1.665  -1.693  -1.545
106   I        -0.651  -0.587  -0.463  -0.971  -0.857  -0.644  -1.033  -0.917  -0.720
107   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
108   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
109   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
110   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
111   I        -0.137  -0.062  -0.394  -0.115  -0.010  -0.516  -0.191  -0.078  -0.602
112   M        -1.325  -1.279  -1.236  -1.257  -1.219  -1.172  -1.454  -1.384  -1.261
113   T        -0.651  -0.577  -0.460  -0.947  -0.817  -0.621  -1.033  -0.900  -0.714
114   M         0.818   0.838   0.876   1.012   1.021   1.075   0.861   0.885   0.936
115   S         0.818   0.838   0.876   0.753   0.787   0.849   0.861   0.885   0.936
116   I         0.818   0.838   0.876   0.773   0.801   0.867   0.861   0.885   0.936
117   T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
118   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
119   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
120   F         0.818   0.838   0.876   0.989   1.004   1.055   0.861   0.885   0.936
121   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
122   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
123   F         0.818   0.838   0.876   0.989   1.004   1.055   0.861   0.885   0.936
124   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
125   C         0.818   0.838   0.876   1.063   1.087   1.119   0.861   0.885   0.936
126   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
127   K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
128   T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
129   Q         0.818   0.838   0.876   0.900   0.929   0.977   0.861   0.885   0.936
130   M        -0.651  -0.598  -0.465  -0.872  -0.763  -0.552  -1.033  -0.935  -0.723
131   S        -0.531  -0.457  -0.445  -0.633  -0.513  -0.477  -0.823  -0.694  -0.688
132   H         0.818   0.838   0.876   1.075   1.095   1.129   0.861   0.885   0.936
133   T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
134   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
135   C         0.818   0.838   0.876   1.063   1.087   1.119   0.861   0.885   0.936
136   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
137   T        -0.137  -0.072  -0.391  -0.058   0.037  -0.484  -0.191  -0.093  -0.596
138   T        -0.137  -0.001  -0.388  -0.155   0.017  -0.522  -0.191   0.007  -0.592
139   Q         0.818   0.838   0.876   0.900   0.929   0.977   0.861   0.885   0.936
140   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
141   P         0.818   0.838   0.876   1.044   1.065   1.102   0.861   0.885   0.936
142   R        -1.325  -1.284  -1.231  -1.382  -1.330  -1.222  -1.454  -1.388  -1.256
143   E        -1.325  -1.232  -1.232  -1.499  -1.362  -1.320  -1.454  -1.341  -1.257
144   M        -0.137  -0.027  -0.393   0.102   0.239  -0.375  -0.191  -0.029  -0.601
145   G        -0.137  -0.027  -0.393  -0.194  -0.044  -0.526  -0.191  -0.029  -0.601
146   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
147   G        -1.815  -1.836  -1.792  -1.843  -1.918  -1.765  -1.665  -1.668  -1.541
148   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
149   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
150   K        -0.137  -0.072  -0.391  -0.031   0.060  -0.429  -0.191  -0.093  -0.596
151   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
152   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
153   Y        -0.531  -0.563  -0.465  -0.389  -0.465  -0.340  -0.823  -0.874  -0.723
154   I         0.818   0.838   0.876   0.773   0.801   0.867   0.861   0.885   0.936
155   D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
156   T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
157   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
158   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
159   T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
160   F         0.818   0.838   0.876   0.989   1.004   1.055   0.861   0.885   0.936
161   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
162   P         0.818   0.838   0.876   1.044   1.065   1.102   0.861   0.885   0.936
163   E        -0.651  -0.577  -0.460  -0.949  -0.799  -0.609  -1.033  -0.900  -0.714
164   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
165   I         0.818   0.838   0.876   0.773   0.801   0.867   0.861   0.885   0.936
166   K        -0.531  -0.457  -0.445  -0.649  -0.524  -0.528  -0.823  -0.694  -0.688
167   Q        -1.325  -1.409  -1.242  -1.422  -1.569  -1.313  -1.454  -1.512  -1.268
168   I         0.818   0.838   0.876   0.773   0.801   0.867   0.861   0.885   0.936
169   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
170   E        -0.137  -0.027  -0.393  -0.146   0.006  -0.508  -0.191  -0.029  -0.601
171   G        -0.531  -0.406  -0.437  -0.736  -0.505  -0.611  -0.823  -0.609  -0.675
172   Y        -0.531  -0.578  -0.466  -0.389  -0.495  -0.343  -0.823  -0.901  -0.725
173   E        -2.000  -1.834  -1.792  -2.113  -1.881  -1.774  -1.875  -1.671  -1.541
174   L        -0.651  -0.577  -0.460  -1.037  -0.875  -0.688  -1.033  -0.900  -0.714
175   D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
176   P        -0.651  -0.577  -0.460  -0.821  -0.738  -0.524  -1.033  -0.900  -0.714
177   E        -0.531  -0.406  -0.437  -0.681  -0.460  -0.558  -0.823  -0.609  -0.675
178   S        -2.489  -2.427  -2.239  -2.459  -2.339  -2.070  -2.086  -1.986  -1.720
179   C        -0.137  -0.366  -0.420   0.160  -0.212  -0.377  -0.191  -0.544  -0.647
180   L        -0.137  -0.366  -0.420  -0.159  -0.456  -0.522  -0.191  -0.544  -0.647
181   A        -0.137  -0.001  -0.388  -0.182   0.007  -0.578  -0.191   0.007  -0.592
182   N         0.818   0.838   0.876   0.961   0.986   1.030   0.861   0.885   0.936
183   V        -0.137  -0.001  -0.388  -0.115   0.068  -0.505  -0.191   0.007  -0.592
184   S        -1.020  -1.095  -1.215  -0.987  -1.129  -1.290  -1.033  -1.137  -1.235
185   Y        -0.137  -0.366  -0.420   0.173  -0.184  -0.345  -0.191  -0.544  -0.647
186   A        -0.137  -0.366  -0.420  -0.173  -0.530  -0.622  -0.191  -0.544  -0.647
187   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
188   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
189   L        -0.137  -0.366  -0.420  -0.148  -0.432  -0.496  -0.191  -0.544  -0.647
190   N         0.818   0.838   0.876   0.961   0.986   1.030   0.861   0.885   0.936
191   S         0.818   0.838   0.876   0.753   0.787   0.849   0.861   0.885   0.936
192   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
193   H        -0.137  -0.366  -0.420   0.204  -0.143  -0.287  -0.191  -0.544  -0.647
194   Q         0.818   0.838   0.876   0.900   0.929   0.977   0.861   0.885   0.936
195   M        -0.137  -0.072  -0.391   0.119   0.191  -0.331  -0.191  -0.093  -0.596
196   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
197   L        -0.137  -0.366  -0.420  -0.148  -0.432  -0.496  -0.191  -0.544  -0.647
198   V        -1.815  -1.836  -1.792  -1.828  -1.886  -1.843  -1.665  -1.668  -1.541
199   E        -0.137  -0.366  -0.420  -0.158  -0.486  -0.579  -0.191  -0.544  -0.647
200   Q        -0.137  -0.366  -0.420   0.022  -0.319  -0.442  -0.191  -0.544  -0.647
201   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
202   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
203   E        -1.815  -1.862  -1.797  -1.797  -1.867  -1.750  -1.665  -1.693  -1.545
204   E        -1.020  -1.155  -1.221  -1.006  -1.228  -1.294  -1.033  -1.204  -1.242
205   L        -0.531  -0.578  -0.466  -0.731  -0.786  -0.582  -0.823  -0.901  -0.725
206   S        -0.651  -0.577  -0.460  -1.037  -0.911  -0.696  -1.033  -0.900  -0.714
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   S        -1.325  -1.285  -1.235  -1.480  -1.412  -1.317  -1.454  -1.390  -1.260
209   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
210   D        -2.489  -2.369  -2.237  -2.389  -2.195  -2.025  -2.086  -1.943  -1.719
211   Y        -0.137  -0.072  -0.391   0.210   0.294  -0.201  -0.191  -0.093  -0.596
212   R        -0.137   0.015  -0.389  -0.034   0.169  -0.428  -0.191   0.030  -0.594
213   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
214   I        -0.531  -0.384  -0.432  -0.833  -0.565  -0.663  -0.823  -0.573  -0.667
215   V        -0.531  -0.424  -0.447  -0.742  -0.556  -0.613  -0.823  -0.638  -0.692
216   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
217   D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
218   S         0.818   0.838   0.876   0.753   0.787   0.849   0.861   0.885   0.936
219   I         0.818   0.838   0.876   0.773   0.801   0.867   0.861   0.885   0.936
220   M         0.818   0.838   0.876   1.012   1.021   1.075   0.861   0.885   0.936
221   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
222   N        -1.325  -1.409  -1.242  -1.210  -1.360  -1.124  -1.454  -1.512  -1.268
223   F         0.818   0.838   0.876   0.989   1.004   1.055   0.861   0.885   0.936
224   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
225   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
226   D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
227   Y         0.818   0.838   0.876   1.063   1.088   1.119   0.861   0.885   0.936
228   C        -0.531  -0.384  -0.432  -0.633  -0.405  -0.462  -0.823  -0.573  -0.667
229   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
230   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
231   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
232   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
233   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
234   S        -0.531  -0.566  -0.466  -0.586  -0.678  -0.548  -0.823  -0.880  -0.724
235   E        -0.137  -0.062  -0.394  -0.152  -0.043  -0.520  -0.191  -0.078  -0.602
236   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
237   Q         0.818   0.838   0.876   0.900   0.929   0.977   0.861   0.885   0.936
238   Q         0.818   0.838   0.876   0.900   0.929   0.977   0.861   0.885   0.936
239   K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
240   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
241   N         0.818   0.838   0.876   0.961   0.986   1.030   0.861   0.885   0.936
242   Q        -0.137  -0.366  -0.420   0.007  -0.344  -0.477  -0.191  -0.544  -0.647
243   H        -0.137  -0.366  -0.420   0.226  -0.112  -0.235  -0.191  -0.544  -0.647
244   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
245   F        -1.325  -1.376  -1.234  -1.412  -1.508  -1.262  -1.454  -1.469  -1.259
246   K        -2.000  -1.870  -1.791  -1.971  -1.765  -1.639  -1.875  -1.702  -1.540
247   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
248   N        -1.020  -0.910  -1.198  -0.784  -0.624  -1.116  -1.033  -0.875  -1.214
249   R        -0.137  -0.366  -0.420   0.013  -0.295  -0.373  -0.191  -0.544  -0.647
250   L        -1.325  -1.285  -1.232  -1.578  -1.506  -1.385  -1.454  -1.389  -1.257
251   A        -0.137  -0.366  -0.420  -0.173  -0.530  -0.622  -0.191  -0.544  -0.647
252   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
253   E        -0.531  -0.457  -0.445  -0.753  -0.627  -0.604  -0.823  -0.694  -0.688
254   F        -1.325  -1.196  -1.224  -1.114  -0.938  -0.965  -1.454  -1.272  -1.247
255   N         0.818   0.838   0.876   0.961   0.986   1.030   0.861   0.885   0.936
256   V        -1.325  -1.153  -1.219  -1.515  -1.232  -1.342  -1.454  -1.222  -1.241
257   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
258   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
259   F         0.818   0.838   0.876   0.989   1.004   1.055   0.861   0.885   0.936
260   L        -1.325  -1.383  -1.235  -1.437  -1.515  -1.262  -1.454  -1.478  -1.260
261   T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
262   N         0.818   0.838   0.876   0.961   0.986   1.030   0.861   0.885   0.936
263   Q         0.818   0.838   0.876   0.900   0.929   0.977   0.861   0.885   0.936
264   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
265   Q         0.818   0.838   0.876   0.900   0.929   0.977   0.861   0.885   0.936
266   S        -0.137  -0.366  -0.420  -0.149  -0.502  -0.614  -0.191  -0.544  -0.647
267   D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
268   P         0.818   0.838   0.876   1.044   1.065   1.102   0.861   0.885   0.936
269   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
270   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
271   S        -0.137  -0.366  -0.420  -0.149  -0.502  -0.614  -0.191  -0.544  -0.647
272   A        -1.020  -1.155  -1.221  -0.979  -1.179  -1.248  -1.033  -1.204  -1.242
273   L        -0.137  -0.366  -0.420  -0.159  -0.456  -0.522  -0.191  -0.544  -0.647
274   F         0.818   0.838   0.876   0.989   1.004   1.055   0.861   0.885   0.936
275   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
276   S        -0.531  -0.457  -0.445  -0.793  -0.663  -0.662  -0.823  -0.694  -0.688
277   A        -0.137  -0.366  -0.420  -0.131  -0.459  -0.519  -0.191  -0.544  -0.647
278   D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
279   G         0.818   0.838   0.876   0.661   0.693   0.769   0.861   0.885   0.936
280   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
281   K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
282   P         0.818   0.838   0.876   1.044   1.065   1.102   0.861   0.885   0.936
283   I        -0.137  -0.001  -0.388  -0.101   0.087  -0.499  -0.191   0.007  -0.592
284   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
285   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
286   H         0.818   0.838   0.876   1.075   1.095   1.129   0.861   0.885   0.936
287   V        -0.137  -0.062  -0.394  -0.101   0.009  -0.510  -0.191  -0.078  -0.602
288   L        -0.137  -0.366  -0.420  -0.159  -0.456  -0.522  -0.191  -0.544  -0.647
289   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
290   H         0.818   0.838   0.876   1.075   1.095   1.129   0.861   0.885   0.936
291   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
292   S         0.818   0.838   0.876   0.753   0.787   0.849   0.861   0.885   0.936
293   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
294   T         0.818   0.838   0.876   0.844   0.877   0.929   0.861   0.885   0.936
295   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
296   I        -0.137  -0.366  -0.420  -0.136  -0.492  -0.617  -0.191  -0.544  -0.647
297   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
298   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
299   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
300   K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
301   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
302   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
303   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
304   D        -0.651  -0.577  -0.460  -0.949  -0.832  -0.626  -1.033  -0.900  -0.714
305   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
306   R         0.818   0.838   0.876   0.844   0.874   0.929   0.861   0.885   0.936
307   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
308   A         0.818   0.838   0.876   0.723   0.741   0.823   0.861   0.885   0.936
309   K         0.818   0.838   0.876   0.847   0.875   0.931   0.861   0.885   0.936
310   L         0.818   0.838   0.876   0.683   0.731   0.789   0.861   0.885   0.936
311   Q        -0.137  -0.366  -0.420   0.044  -0.281  -0.387  -0.191  -0.544  -0.647
312   D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
313   S         0.818   0.838   0.876   0.753   0.787   0.849   0.861   0.885   0.936
314   P         0.818   0.838   0.876   1.044   1.065   1.102   0.861   0.885   0.936
315   D        -0.137  -0.072  -0.391   0.018   0.103  -0.357  -0.191  -0.093  -0.596
316   M         0.818   0.838   0.876   1.012   1.021   1.075   0.861   0.885   0.936
317   P        -0.137  -0.062  -0.394   0.140   0.239  -0.335  -0.191  -0.078  -0.602
318   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
319   K        -1.020  -1.095  -1.215  -0.907  -1.071  -1.248  -1.033  -1.137  -1.235
320   E         0.818   0.838   0.876   0.720   0.754   0.820   0.861   0.885   0.936
321   C         0.818   0.838   0.876   1.063   1.087   1.119   0.861   0.885   0.936
322   V        -0.137  -0.366  -0.420  -0.105  -0.450  -0.569  -0.191  -0.544  -0.647
323   Y         0.818   0.838   0.876   1.063   1.088   1.119   0.861   0.885   0.936
324   V         0.818   0.838   0.876   0.791   0.824   0.883   0.861   0.885   0.936
325   I         0.818   0.838   0.876   0.773   0.801   0.867   0.861   0.885   0.936
326   G        -0.137  -0.366  -0.420  -0.218  -0.545  -0.624  -0.191  -0.544  -0.647
327   E        -0.137  -0.366  -0.420  -0.117  -0.418  -0.480  -0.191  -0.544  -0.647
328   K        -1.020  -0.817  -1.189  -1.061  -0.772  -1.282  -1.033  -0.758  -1.203
329   G         0.818   0.838   0.876   0.659   0.693   0.768   0.861   0.885   0.936
330   I         0.818   0.838   0.876   0.773   0.801   0.867   0.861   0.885   0.936
331   T        -2.000  -1.837  -1.792  -2.004  -1.801  -1.650  -1.875  -1.680  -1.541
332   D         0.818   0.838   0.876   0.874   0.897   0.954   0.861   0.885   0.936
333   S        -1.020  -1.163  -1.218  -0.983  -1.211  -1.285  -1.033  -1.214  -1.238
334   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   D        -1.325  -1.398  -1.235  -1.499  -1.602  -1.329  -1.454  -1.497  -1.260
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25453
Output conservation file - output/P25453
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
