1     M         1.966   2.006   2.135   2.230   2.292   2.513   2.247   2.316   2.555
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     N         1.966   2.006   2.135   2.046   2.109   2.324   2.247   2.316   2.555
4     A        -0.057  -0.040   0.033  -0.223  -0.212  -0.113  -0.337  -0.323  -0.232
5     L         0.214   0.179   0.139  -0.030  -0.073  -0.138   0.051   0.013  -0.078
6     Y         0.535   0.455   0.264   0.937   0.839   0.583   0.567   0.448   0.136
7     N         1.233   1.294   1.089   1.399   1.489   1.223   1.342   1.443   1.056
8     H         1.233   1.164   1.072   1.577   1.485   1.350   1.342   1.224   1.022
9     A        -0.394  -0.397  -0.433  -0.292  -0.276  -0.339  -0.466  -0.448  -0.487
10    V        -1.069  -1.076  -0.969  -1.183  -1.198  -1.042  -0.983  -0.979  -0.841
11    K         1.966   2.006   2.135   1.934   2.001   2.210   2.247   2.316   2.555
12    Q         1.233   1.161   1.070   1.220   1.136   0.961   1.342   1.220   1.018
13    K        -1.406  -1.456  -1.360  -1.352  -1.420  -1.281  -1.112  -1.141  -1.014
14    N        -0.942  -0.918  -0.929  -0.977  -0.936  -0.958  -0.854  -0.830  -0.802
15    Q        -0.604  -0.498  -0.513  -0.984  -0.797  -0.856  -0.725  -0.597  -0.592
16    L         0.617   0.646   0.775   0.178   0.223   0.421   0.180   0.220   0.405
17    Q        -0.942  -0.946  -0.928  -0.974  -0.956  -0.952  -0.854  -0.842  -0.794
18    Q         0.214   0.188   0.168   0.109   0.098   0.030   0.051   0.028  -0.026
19    E         0.535   0.508   0.292   0.752   0.711   0.378   0.567   0.524   0.180
20    L         1.233   1.294   1.089   1.085   1.165   0.908   1.342   1.443   1.056
21    A        -0.942  -0.922  -0.917  -0.883  -0.854  -0.843  -0.854  -0.825  -0.788
22    R        -1.406  -1.345  -1.332  -1.466  -1.367  -1.365  -1.112  -1.058  -0.992
23    F         0.872   0.794   0.843   0.826   0.650   0.665   0.696   0.526   0.551
24    E         0.872   0.837   0.855   0.740   0.666   0.648   0.696   0.614   0.577
25    K        -0.732  -0.845  -0.901  -0.640  -0.824  -0.946  -0.595  -0.722  -0.763
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    N        -0.942  -0.965  -0.915  -0.847  -0.874  -0.799  -0.854  -0.872  -0.786
32    S        -0.942  -0.975  -0.937  -1.073  -1.108  -1.022  -0.854  -0.885  -0.809
33    V        -1.069  -1.085  -0.977  -1.237  -1.273  -1.109  -0.983  -0.985  -0.846
34    T        -0.123  -0.278  -0.410   0.124  -0.091  -0.300  -0.079  -0.282  -0.453
35    A         0.637   0.656   0.781   0.402   0.410   0.608   0.222   0.241   0.418
36    P         1.233   1.161   1.070   1.577   1.479   1.321   1.342   1.220   1.018
37    I        -0.942  -1.008  -0.967  -0.930  -0.996  -0.934  -0.854  -0.904  -0.834
38    S         1.233   1.161   1.070   1.263   1.169   1.060   1.342   1.220   1.018
39    L         1.233   1.161   1.070   1.085   0.994   0.878   1.342   1.220   1.018
40    Q         1.233   1.164   1.072   1.261   1.193   1.051   1.342   1.224   1.022
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    G         1.966   2.006   2.135   2.075   2.130   2.355   2.247   2.316   2.555
46    S        -0.057  -0.047   0.017  -0.328  -0.330  -0.243  -0.337  -0.328  -0.256
47    I         1.233   1.164   1.072   1.363   1.266   1.109   1.342   1.224   1.022
48    S         0.214   0.329   0.205   0.127   0.305   0.127   0.051   0.238   0.038
49    A         0.679   0.758   0.825   0.504   0.635   0.724   0.309   0.454   0.514
50    T         0.617   0.646   0.775   0.278   0.313   0.515   0.180   0.220   0.405
51    L         0.535   0.453   0.264   0.489   0.385   0.153   0.567   0.445   0.136
52    V         0.070   0.033   0.089  -0.031  -0.083  -0.019  -0.208  -0.240  -0.160
53    S         0.617   0.647   0.775   0.293   0.316   0.530   0.180   0.220   0.405
54    L         0.872   0.866   0.855   0.826   0.800   0.695   0.696   0.671   0.577
55    E        -0.942  -0.910  -0.951  -1.002  -0.978  -1.030  -0.854  -0.829  -0.821
56    K         0.679   0.661   0.777   0.412   0.361   0.540   0.309   0.251   0.408
57    T         1.233   1.161   1.070   1.351   1.263   1.120   1.342   1.220   1.018
58    V         0.214   0.275   0.154   0.180   0.260   0.045   0.051   0.133  -0.056
59    K        -0.942  -0.816  -0.911  -0.822  -0.616  -0.770  -0.854  -0.711  -0.782
60    Q        -0.140  -0.139  -0.019  -0.437  -0.422  -0.249  -0.466  -0.466  -0.310
61    Y         1.966   2.006   2.135   2.184   2.246   2.466   2.247   2.316   2.555
62    A        -1.069  -1.071  -0.976  -1.152  -1.145  -1.000  -0.983  -0.976  -0.847
63    E        -0.942  -0.985  -0.934  -0.887  -0.932  -0.870  -0.854  -0.882  -0.800
64    H        -0.942  -0.970  -0.948  -0.934  -0.958  -0.904  -0.854  -0.871  -0.816
65    L        -1.406  -1.416  -1.321  -1.301  -1.296  -1.152  -1.112  -1.111  -0.984
66    N        -1.406  -1.355  -1.312  -1.365  -1.295  -1.234  -1.112  -1.065  -0.977
67    R        -0.140  -0.130  -0.010  -0.477  -0.456  -0.287  -0.466  -0.454  -0.297
68    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    T        -0.477  -0.411  -0.466  -0.523  -0.428  -0.484  -0.595  -0.514  -0.542
75    N        -1.406  -1.309  -1.332  -1.347  -1.248  -1.225  -1.112  -1.025  -0.993
76    A        -0.732  -0.669  -0.812  -0.487  -0.385  -0.626  -0.595  -0.523  -0.665
77    E        -0.942  -1.027  -0.954  -0.805  -0.907  -0.808  -0.854  -0.926  -0.822
78    E        -0.394  -0.370  -0.443  -0.420  -0.414  -0.506  -0.466  -0.463  -0.509
79    I        -0.942  -0.831  -0.915  -1.078  -0.875  -1.048  -0.854  -0.721  -0.780
80    D        -0.942  -0.870  -0.902  -0.883  -0.786  -0.812  -0.854  -0.776  -0.768
81    P        -1.406  -1.359  -1.336  -1.281  -1.236  -1.227  -1.112  -1.067  -0.996
82    K         1.966   2.006   2.135   1.934   2.001   2.210   2.247   2.316   2.555
83    F        -0.604  -0.504  -0.505  -0.452  -0.329  -0.294  -0.725  -0.600  -0.580
84    A        -0.123  -0.231  -0.361   0.070  -0.077  -0.266  -0.079  -0.223  -0.390
85    N        -1.406  -1.444  -1.326  -1.367  -1.428  -1.271  -1.112  -1.133  -0.988
86    R         1.966   2.006   2.135   2.022   2.067   2.300   2.247   2.316   2.555
87    L         0.872   0.794   0.843   0.571   0.431   0.498   0.696   0.526   0.551
88    A        -0.942  -0.943  -0.913  -0.870  -0.898  -0.829  -0.854  -0.857  -0.785
89    T        -1.406  -1.450  -1.357  -1.403  -1.457  -1.338  -1.112  -1.137  -1.012
90    L         0.679   0.731   0.824   0.408   0.505   0.618   0.309   0.397   0.512
91    T        -0.604  -0.511  -0.505  -0.689  -0.541  -0.541  -0.725  -0.605  -0.580
92    Q        -0.123  -0.174  -0.349  -0.063  -0.127  -0.443  -0.079  -0.145  -0.373
93    D         0.214   0.104   0.095   0.244   0.060   0.002   0.051  -0.115  -0.147
94    L         0.214   0.210   0.134   0.082   0.070   0.022   0.051   0.031  -0.089
95    H        -1.743  -1.698  -1.635  -1.407  -1.311  -1.267  -1.241  -1.199  -1.098
96    D         0.535   0.528   0.291   0.753   0.744   0.378   0.567   0.553   0.179
97    F         0.214   0.152   0.130   0.262   0.155   0.072   0.051  -0.034  -0.095
98    T        -0.942  -0.977  -0.947  -0.955  -1.045  -1.002  -0.854  -0.888  -0.818
99    A        -0.604  -0.641  -0.535  -0.793  -0.854  -0.687  -0.725  -0.756  -0.618
100   K         0.535   0.455   0.264   0.611   0.511   0.192   0.567   0.448   0.136
101   F         1.233   1.164   1.072   1.408   1.313   1.154   1.342   1.224   1.022
102   K         0.070   0.110   0.096  -0.051   0.021  -0.000  -0.208  -0.150  -0.156
103   D        -0.942  -0.872  -0.914  -0.962  -0.868  -0.918  -0.854  -0.782  -0.786
104   L         1.966   2.006   2.135   1.732   1.786   2.003   2.247   2.316   2.555
105   K         1.233   1.252   1.080   1.283   1.320   1.086   1.342   1.374   1.037
106   Q        -0.604  -0.626  -0.540  -0.866  -0.884  -0.770  -0.725  -0.738  -0.623
107   S        -0.942  -0.926  -0.916  -0.961  -0.890  -0.891  -0.854  -0.822  -0.781
108   Y         0.070   0.033   0.089   0.082   0.036   0.148  -0.208  -0.240  -0.160
109   N        -1.069  -1.073  -0.986  -1.092  -1.106  -0.983  -0.983  -0.975  -0.854
110   E        -0.123  -0.054  -0.332   0.030   0.131  -0.289  -0.079   0.008  -0.352
111   N        -1.406  -1.368  -1.326  -1.232  -1.155  -1.112  -1.112  -1.075  -0.987
112   -        -1.166  -1.138  -1.025  -1.160  -1.100  -0.956  -1.060  -1.029  -0.888
113   -         0.117   0.084   0.087   0.011  -0.030  -0.072  -0.068  -0.123  -0.146
114   -         0.657   0.655   0.777   0.387   0.363   0.559   0.262   0.238   0.410
115   N        -1.279  -1.293  -1.325  -1.118  -1.159  -1.250  -0.983  -0.996  -0.984
116   S         0.214   0.296   0.158   0.242   0.364   0.137   0.051   0.169  -0.042
117   R         0.679   0.749   0.819   0.443   0.561   0.646   0.309   0.436   0.500
118   T        -1.406  -1.442  -1.340  -1.408  -1.445  -1.305  -1.112  -1.131  -0.997
119   Q        -0.394  -0.345  -0.442  -0.469  -0.376  -0.552  -0.466  -0.396  -0.502
120   L         1.966   2.006   2.135   1.732   1.786   2.003   2.247   2.316   2.555
121   F         0.617   0.646   0.775   0.212   0.241   0.442   0.180   0.220   0.405
122   G         0.535   0.597   0.299   0.774   0.861   0.433   0.567   0.662   0.192
123   S         0.106   0.187   0.111  -0.004   0.121  -0.027  -0.116   0.011  -0.115
124   G        -0.279  -0.164  -0.405  -0.066   0.085  -0.257  -0.284  -0.129  -0.447
125   A        -0.621  -0.665  -0.560  -0.433  -0.504  -0.327  -0.739  -0.777  -0.643
126   S        -0.626  -0.642  -0.557  -0.684  -0.702  -0.565  -0.730  -0.747  -0.638
127   H        -0.626  -0.557  -0.530  -0.490  -0.385  -0.349  -0.730  -0.642  -0.606
128   V        -0.087  -0.120   0.001  -0.194  -0.240  -0.057  -0.399  -0.439  -0.281
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   M        -1.166  -1.146  -1.025  -1.292  -1.272  -1.091  -1.060  -1.036  -0.888
138   D        -0.087  -0.088   0.024  -0.328  -0.343  -0.175  -0.399  -0.397  -0.250
139   S        -0.626  -0.636  -0.536  -0.815  -0.842  -0.688  -0.730  -0.741  -0.613
140   D         0.106   0.139   0.123   0.052   0.105   0.046  -0.116  -0.069  -0.105
141   N         1.089   1.045   1.001   1.178   1.107   1.017   1.098   1.012   0.881
142   P         1.966   2.006   2.135   2.265   2.326   2.549   2.247   2.316   2.555
143   F         1.089   1.066   1.005   1.359   1.332   1.239   1.098   1.051   0.890
144   S        -1.435  -1.364  -1.337  -1.311  -1.200  -1.186  -1.128  -1.059  -0.994
145   T        -1.050  -1.040  -0.957  -1.035  -1.007  -0.906  -0.959  -0.943  -0.827
146   S        -0.394  -0.395  -0.416  -0.433  -0.433  -0.463  -0.466  -0.450  -0.475
147   E        -0.904  -0.974  -0.961  -0.860  -0.976  -0.975  -0.790  -0.863  -0.825
148   T        -0.519  -0.511  -0.480  -0.551  -0.539  -0.506  -0.622  -0.610  -0.554
149   I        -1.050  -1.081  -0.997  -0.772  -0.838  -0.716  -0.959  -0.981  -0.863
150   M        -0.904  -0.917  -0.961  -0.618  -0.659  -0.774  -0.790  -0.808  -0.825
151   N        -0.519  -0.581  -0.527  -0.570  -0.631  -0.569  -0.622  -0.679  -0.605
152   K        -0.519  -0.600  -0.513  -0.730  -0.842  -0.732  -0.622  -0.705  -0.590
153   R         0.106   0.076   0.104  -0.007  -0.048  -0.037  -0.116  -0.140  -0.122
154   N        -1.050  -1.088  -0.998  -1.073  -1.116  -0.975  -0.959  -0.986  -0.864
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.071  -1.122  -1.013  -1.038  -1.099  -0.938  -0.969  -1.013  -0.877
162   -        -1.071  -1.122  -1.013  -1.064  -1.139  -0.970  -0.969  -1.013  -0.877
163   -        -0.626  -0.619  -0.529  -0.671  -0.658  -0.545  -0.730  -0.719  -0.605
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   S        -1.050  -1.028  -0.955  -1.117  -1.082  -0.968  -0.959  -0.934  -0.825
182   S        -0.904  -0.912  -0.908  -0.807  -0.827  -0.805  -0.790  -0.795  -0.770
183   N        -0.904  -0.887  -0.901  -0.884  -0.863  -0.893  -0.790  -0.768  -0.762
184   G        -1.821  -1.802  -1.685  -1.530  -1.494  -1.334  -1.297  -1.274  -1.134
185   G        -1.435  -1.350  -1.338  -1.314  -1.207  -1.164  -1.128  -1.043  -0.995
186   G        -0.394  -0.300  -0.443  -0.294  -0.178  -0.386  -0.466  -0.373  -0.509
187   L         0.214   0.234   0.187   0.050   0.083   0.034   0.051   0.103   0.009
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   P         0.070   0.097   0.095   0.020   0.052   0.078  -0.208  -0.163  -0.150
195   L        -0.604  -0.511  -0.505  -0.683  -0.549  -0.514  -0.725  -0.605  -0.580
196   Y        -0.604  -0.573  -0.542  -0.640  -0.616  -0.588  -0.725  -0.698  -0.628
197   Q        -0.057  -0.082  -0.001  -0.269  -0.312  -0.216  -0.337  -0.380  -0.283
198   G         1.233   1.164   1.072   1.456   1.375   1.282   1.342   1.224   1.022
199   L         0.535   0.455   0.264   0.478   0.371   0.133   0.567   0.448   0.136
200   Q        -0.604  -0.576  -0.521  -0.825  -0.828  -0.729  -0.725  -0.692  -0.602
201   K         0.214   0.242   0.138   0.195   0.204   0.097   0.051   0.063  -0.080
202   E         1.966   2.006   2.135   1.955   2.017   2.232   2.247   2.316   2.555
203   Q        -0.394  -0.380  -0.416  -0.423  -0.346  -0.411  -0.466  -0.427  -0.465
204   S        -0.394  -0.325  -0.460  -0.417  -0.354  -0.505  -0.466  -0.415  -0.530
205   V        -0.604  -0.583  -0.539  -0.679  -0.652  -0.551  -0.725  -0.706  -0.623
206   F         0.617   0.645   0.774   0.212   0.252   0.451   0.180   0.217   0.403
207   E        -1.279  -1.316  -1.295  -1.129  -1.191  -1.171  -0.983  -1.016  -0.957
208   R         0.535   0.455   0.264   0.691   0.567   0.262   0.567   0.448   0.136
209   G        -0.123  -0.278  -0.410   0.177  -0.052  -0.255  -0.079  -0.282  -0.453
210   N        -1.279  -1.293  -1.325  -1.014  -1.029  -1.103  -0.983  -0.996  -0.984
211   A        -0.604  -0.563  -0.543  -0.797  -0.766  -0.739  -0.725  -0.687  -0.629
212   Q         0.535   0.477   0.287   0.661   0.600   0.345   0.567   0.480   0.173
213   L         1.233   1.161   1.070   1.097   1.010   0.904   1.342   1.220   1.018
214   D         1.966   2.006   2.135   2.075   2.135   2.355   2.247   2.316   2.555
215   Y        -1.743  -1.743  -1.645  -1.362  -1.402  -1.209  -1.241  -1.235  -1.105
216   I         0.214   0.105   0.094   0.325   0.165   0.151   0.051  -0.115  -0.149
217   L         0.872   0.837   0.855   0.571   0.504   0.518   0.696   0.614   0.577
218   E        -0.123  -0.101  -0.312   0.027   0.056  -0.260  -0.079  -0.052  -0.324
219   M         0.214   0.141   0.094   0.411   0.258   0.162   0.051  -0.083  -0.148
220   G         1.966   2.006   2.135   2.075   2.130   2.355   2.247   2.316   2.555
221   Q         0.535   0.453   0.264   0.655   0.563   0.300   0.567   0.445   0.136
222   Q        -0.394  -0.475  -0.478  -0.399  -0.502  -0.502  -0.466  -0.568  -0.552
223   S        -0.477  -0.567  -0.501  -0.539  -0.657  -0.529  -0.595  -0.677  -0.580
224   F         0.679   0.771   0.835   0.276   0.415   0.511   0.309   0.480   0.534
225   E         0.070   0.094   0.084  -0.051  -0.023   0.003  -0.208  -0.190  -0.175
226   N         1.233   1.312   1.095   1.427   1.537   1.259   1.342   1.473   1.067
227   I         0.679   0.661   0.777   0.367   0.277   0.431   0.309   0.251   0.408
228   V        -0.394  -0.443  -0.440  -0.166  -0.226  -0.240  -0.466  -0.514  -0.501
229   E         1.233   1.164   1.072   1.288   1.205   1.062   1.342   1.224   1.022
230   Q         1.966   2.006   2.135   1.912   1.987   2.188   2.247   2.316   2.555
231   N        -0.123  -0.278  -0.410   0.111  -0.116  -0.350  -0.079  -0.282  -0.453
232   K        -1.279  -1.284  -1.307  -1.206  -1.220  -1.294  -0.983  -0.983  -0.967
233   I         0.214   0.270   0.152   0.307   0.367   0.209   0.051   0.104  -0.062
234   L         1.233   1.164   1.072   1.112   1.032   0.938   1.342   1.224   1.022
235   S        -0.942  -0.909  -0.943  -1.059  -1.037  -1.131  -0.854  -0.827  -0.814
236   K        -0.942  -1.021  -0.937  -0.957  -1.072  -0.952  -0.854  -0.920  -0.807
237   V        -0.140  -0.082  -0.007  -0.395  -0.294  -0.227  -0.466  -0.388  -0.293
238   Q         0.535   0.453   0.264   0.613   0.519   0.218   0.567   0.445   0.136
239   D        -1.069  -1.089  -0.975  -1.130  -1.154  -0.996  -0.983  -0.989  -0.845
240   R         0.214   0.296   0.158   0.109   0.241   0.011   0.051   0.169  -0.042
241   M        -0.394  -0.459  -0.454  -0.157  -0.243  -0.277  -0.466  -0.522  -0.514
242   S        -1.406  -1.456  -1.360  -1.455  -1.539  -1.388  -1.112  -1.141  -1.014
243   N        -1.406  -1.315  -1.315  -1.383  -1.264  -1.251  -1.112  -1.033  -0.980
244   G        -0.604  -0.631  -0.529  -0.675  -0.709  -0.545  -0.725  -0.744  -0.613
245   L         0.214   0.105   0.094  -0.025  -0.195  -0.191   0.051  -0.115  -0.149
246   R        -1.406  -1.322  -1.335  -1.170  -1.063  -1.045  -1.112  -1.034  -0.994
247   T         1.233   1.276   1.089   1.383   1.452   1.219   1.342   1.414   1.055
248   L         1.966   2.006   2.135   1.732   1.786   2.003   2.247   2.316   2.555
249   G         1.966   2.006   2.135   2.075   2.130   2.355   2.247   2.316   2.555
250   V         0.214   0.141   0.094   0.301   0.155   0.041   0.051  -0.083  -0.148
251   S         1.233   1.161   1.070   1.255   1.160   1.042   1.342   1.220   1.018
252   E        -1.069  -1.073  -0.984  -1.148  -1.130  -0.995  -0.983  -0.974  -0.852
253   Q        -0.942  -0.975  -0.931  -0.840  -0.857  -0.800  -0.854  -0.872  -0.796
254   T         1.966   2.006   2.135   2.019   2.083   2.297   2.247   2.316   2.555
255   I         1.233   1.161   1.070   1.363   1.263   1.105   1.342   1.220   1.018
256   T        -1.279  -1.284  -1.307  -1.182  -1.210  -1.292  -0.983  -0.983  -0.967
257   S        -1.069  -1.074  -0.972  -1.119  -1.114  -0.995  -0.983  -0.976  -0.844
258   I         0.872   0.932   0.878   0.910   1.002   0.899   0.696   0.800   0.627
259   N         0.617   0.645   0.774   0.333   0.378   0.573   0.180   0.218   0.403
260   K         0.679   0.673   0.782   0.412   0.385   0.548   0.309   0.277   0.419
261   R         1.966   2.006   2.135   2.022   2.067   2.300   2.247   2.316   2.555
262   V        -0.394  -0.414  -0.450  -0.364  -0.405  -0.494  -0.466  -0.478  -0.511
263   F         0.070   0.097   0.095  -0.064  -0.017  -0.003  -0.208  -0.163  -0.150
264   K         0.679   0.731   0.824   0.345   0.451   0.560   0.309   0.397   0.512
265   D         1.966   2.006   2.135   2.075   2.135   2.355   2.247   2.316   2.555
266   K         1.966   2.006   2.135   1.934   2.001   2.210   2.247   2.316   2.555
267   L        -0.477  -0.522  -0.497  -0.486  -0.539  -0.475  -0.595  -0.633  -0.575
268   V        -0.394  -0.286  -0.401  -0.397  -0.195  -0.368  -0.466  -0.312  -0.446
269   F         1.966   2.006   2.135   2.099   2.160   2.379   2.247   2.316   2.555
270   W         0.070   0.099   0.103   0.294   0.325   0.353  -0.208  -0.180  -0.151
271   I        -1.406  -1.353  -1.335  -1.186  -1.094  -1.074  -1.112  -1.063  -0.994
272   A        -0.394  -0.247  -0.403  -0.207   0.003  -0.191  -0.466  -0.268  -0.457
273   L        -1.069  -1.052  -0.972  -1.118  -1.094  -0.941  -0.983  -0.963  -0.843
274   I        -0.394  -0.363  -0.450  -0.261  -0.226  -0.385  -0.466  -0.437  -0.520
275   L        -0.057  -0.022   0.009  -0.352  -0.306  -0.233  -0.337  -0.289  -0.267
276   L        -1.069  -1.050  -0.971  -1.026  -0.986  -0.848  -0.983  -0.961  -0.842
277   I        -0.057  -0.077   0.024  -0.389  -0.417  -0.261  -0.337  -0.376  -0.246
278   I         0.214   0.233   0.145   0.242   0.234   0.067   0.051   0.058  -0.073
279   G        -0.942  -0.982  -0.954  -0.674  -0.761  -0.687  -0.854  -0.886  -0.824
280   I        -0.394  -0.407  -0.446  -0.163  -0.157  -0.194  -0.466  -0.472  -0.507
281   Y         0.872   0.890   0.877   1.089   1.119   1.097   0.696   0.718   0.623
282   Y         0.214   0.160   0.121   0.298   0.146   0.085   0.051  -0.059  -0.107
283   V         0.617   0.645   0.774   0.470   0.510   0.712   0.180   0.217   0.403
284   L         0.535   0.528   0.291   0.486   0.478   0.188   0.567   0.553   0.179
285   K         0.535   0.375   0.245   0.679   0.477   0.297   0.567   0.327   0.106
286   W        -0.123  -0.052  -0.330   0.365   0.475   0.025  -0.079   0.011  -0.348
287   L         0.679   0.670   0.781   0.408   0.344   0.484   0.309   0.269   0.417
288   R         0.535   0.558   0.295   0.718   0.739   0.369   0.567   0.604   0.186
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25385
Output conservation file - output/P25385
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
