1     M         1.102   1.124   1.172   1.332   1.360   1.419   1.162   1.191   1.263
2     N        -1.161  -1.072  -1.264  -0.939  -0.848  -1.110  -1.036  -0.941  -1.107
3     S        -1.014  -0.955  -0.812  -1.191  -1.106  -0.891  -1.182  -1.096  -0.903
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.506  -1.529  -1.321  -1.843  -1.854  -1.528  -1.431  -1.422  -1.166
6     -        -0.882  -0.765  -0.771  -0.866  -0.686  -0.691  -1.032  -0.868  -0.854
7     L        -1.959  -1.950  -1.741  -2.110  -2.103  -1.740  -1.630  -1.596  -1.343
8     V        -1.959  -1.800  -1.719  -1.962  -1.673  -1.637  -1.630  -1.466  -1.326
9     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    L        -0.937  -0.720  -0.783  -1.291  -0.886  -1.075  -1.082  -0.785  -0.866
16    F        -0.937  -0.946  -0.814  -1.291  -1.369  -1.147  -1.082  -1.091  -0.905
17    E        -0.001  -0.162  -0.063   0.188  -0.078   0.057  -0.184  -0.467  -0.330
18    R        -0.937  -0.946  -0.814  -0.905  -0.971  -0.764  -1.082  -1.091  -0.905
19    Y        -0.882  -0.939  -0.797  -1.102  -1.223  -1.019  -1.032  -1.083  -0.886
20    P         0.218   0.145   0.013   0.380   0.285   0.079   0.165   0.049  -0.196
21    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    L        -1.403  -1.382  -1.303  -1.577  -1.507  -1.417  -1.329  -1.289  -1.149
27    P         1.102   1.124   1.172   1.162   1.190   1.267   1.162   1.191   1.263
28    T        -0.072  -0.092  -0.062  -0.205  -0.245  -0.214  -0.303  -0.345  -0.327
29    L        -1.403  -1.345  -1.297  -1.599  -1.523  -1.408  -1.329  -1.256  -1.144
30    E        -0.072   0.086  -0.009   0.117   0.351   0.174  -0.303  -0.045  -0.234
31    R        -1.161  -0.977  -1.255  -0.868  -0.617  -1.088  -1.036  -0.817  -1.098
32    P         1.102   1.124   1.172   1.162   1.190   1.267   1.162   1.191   1.263
33    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
35    N        -0.238  -0.124  -0.057  -0.323  -0.144  -0.048  -0.596  -0.400  -0.319
36    I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
37    S        -2.326  -2.285  -2.068  -1.907  -1.851  -1.553  -1.768  -1.708  -1.450
38    L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
39    W         1.102   1.124   1.172   1.294   1.321   1.385   1.162   1.191   1.263
40    E        -1.403  -1.306  -1.294  -1.169  -1.048  -1.016  -1.329  -1.200  -1.138
41    H        -1.403  -1.203  -1.287  -1.391  -1.123  -1.225  -1.329  -1.089  -1.132
42    F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
43    D         0.297   0.156   0.024   0.604   0.406   0.160   0.283   0.067  -0.176
44    D        -1.938  -1.821  -1.717  -1.624  -1.477  -1.293  -1.622  -1.500  -1.325
45    V        -1.403  -1.167  -1.291  -1.499  -1.127  -1.350  -1.329  -1.065  -1.137
46    V        -1.403  -1.501  -1.323  -1.505  -1.616  -1.337  -1.329  -1.395  -1.167
47    T        -0.773  -0.798  -0.787  -0.753  -0.788  -0.750  -0.889  -0.937  -0.875
48    R        -1.791  -1.683  -1.697  -1.533  -1.385  -1.447  -1.475  -1.362  -1.308
49    V        -0.868  -0.888  -0.773  -1.130  -1.154  -0.993  -1.036  -1.026  -0.858
50    T        -1.161  -1.313  -1.299  -1.075  -1.328  -1.341  -1.036  -1.196  -1.143
51    N        -0.762  -0.761  -0.787  -0.490  -0.494  -0.557  -0.848  -0.842  -0.871
52    G         0.120   0.091  -0.037   0.247   0.207  -0.006   0.013  -0.038  -0.284
53    R        -0.773  -0.748  -0.781  -0.691  -0.709  -0.701  -0.889  -0.888  -0.866
54    F        -0.460  -0.680  -0.752  -0.356  -0.653  -0.743  -0.450  -0.732  -0.826
55    V        -0.773  -0.748  -0.781  -0.891  -0.880  -0.899  -0.889  -0.888  -0.866
56    P        -0.072  -0.166  -0.074  -0.094  -0.284  -0.153  -0.303  -0.475  -0.349
57    S         0.297   0.156   0.024   0.424   0.244   0.060   0.283   0.067  -0.176
58    E        -1.938  -1.957  -1.732  -1.494  -1.519  -1.228  -1.622  -1.601  -1.336
59    F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
60    Q        -1.791  -1.831  -1.720  -1.428  -1.525  -1.404  -1.475  -1.497  -1.327
61    F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
62    I        -0.072   0.026  -0.044  -0.315  -0.138  -0.295  -0.303  -0.144  -0.296
63    A        -1.938  -1.957  -1.732  -1.712  -1.723  -1.394  -1.622  -1.601  -1.336
64    G         0.297   0.199   0.029   0.455   0.332   0.088   0.283   0.134  -0.168
65    E        -0.460  -0.515  -0.720  -0.047  -0.119  -0.421  -0.450  -0.520  -0.785
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    L        -0.460  -0.680  -0.752  -0.614  -0.931  -1.043  -0.450  -0.732  -0.826
69    P         1.102   1.124   1.172   1.162   1.190   1.267   1.162   1.191   1.263
70    L        -0.773  -0.889  -0.787  -1.032  -1.164  -0.955  -0.889  -1.019  -0.874
71    S         1.102   1.124   1.172   1.100   1.127   1.211   1.162   1.191   1.263
72    T        -0.773  -0.736  -0.751  -0.753  -0.689  -0.710  -0.889  -0.809  -0.827
73    L        -0.460  -0.516  -0.719  -0.610  -0.684  -0.983  -0.450  -0.522  -0.783
74    P        -1.161  -1.074  -1.261  -0.857  -0.764  -1.027  -1.036  -0.942  -1.105
75    P        -0.072  -0.113  -0.071  -0.023  -0.096  -0.041  -0.303  -0.381  -0.343
76    V        -0.460  -0.552  -0.727  -0.436  -0.556  -0.836  -0.450  -0.572  -0.794
77    L        -1.161  -1.313  -1.299  -1.297  -1.531  -1.495  -1.036  -1.196  -1.143
78    Y        -1.791  -1.582  -1.687  -1.707  -1.413  -1.569  -1.475  -1.252  -1.300
79    A        -0.460  -0.554  -0.724  -0.347  -0.499  -0.797  -0.450  -0.574  -0.790
80    I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
81    T        -1.938  -1.957  -1.729  -1.960  -2.013  -1.673  -1.622  -1.601  -1.334
82    A        -1.403  -1.390  -1.305  -1.514  -1.526  -1.376  -1.329  -1.304  -1.151
83    Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
84    Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
85    V        -1.161  -1.098  -1.260  -1.194  -1.110  -1.419  -1.036  -0.967  -1.104
86    I        -0.072  -0.086  -0.066  -0.315  -0.335  -0.338  -0.303  -0.334  -0.335
87    I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
88    F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
89    G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
90    G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
91    R        -1.161  -0.977  -1.255  -0.738  -0.504  -0.887  -1.036  -0.817  -1.098
92    F        -1.549  -1.416  -1.327  -1.536  -1.303  -1.198  -1.475  -1.325  -1.171
93    L        -0.868  -0.807  -0.771  -1.298  -1.196  -1.104  -1.036  -0.951  -0.857
94    L        -1.014  -0.988  -0.818  -1.297  -1.174  -0.932  -1.182  -1.137  -0.910
95    S        -1.014  -0.953  -0.808  -1.048  -0.947  -0.744  -1.182  -1.099  -0.898
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    K        -1.161  -0.917  -1.246  -0.760  -0.426  -0.932  -1.036  -0.749  -1.089
99    S        -1.403  -1.501  -1.323  -1.466  -1.628  -1.369  -1.329  -1.395  -1.167
100   K        -0.773  -0.857  -0.782  -0.655  -0.772  -0.671  -0.889  -0.982  -0.869
101   P         1.102   1.124   1.172   1.162   1.190   1.267   1.162   1.191   1.263
102   F         0.297   0.199   0.029   0.276   0.142  -0.134   0.283   0.134  -0.168
103   K        -0.773  -0.809  -0.769  -0.763  -0.786  -0.759  -0.889  -0.912  -0.851
104   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
105   N         0.297   0.156   0.024   0.579   0.401   0.173   0.283   0.067  -0.176
106   G        -1.161  -1.262  -1.293  -0.921  -1.083  -1.156  -1.036  -1.146  -1.137
107   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
108   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
109   Q         0.297   0.156   0.024   0.501   0.292   0.004   0.283   0.067  -0.176
110   L        -0.238  -0.219  -0.082  -0.762  -0.718  -0.467  -0.596  -0.569  -0.363
111   H         1.102   1.124   1.172   1.272   1.308   1.365   1.162   1.191   1.263
112   N         1.102   1.124   1.172   1.265   1.303   1.359   1.162   1.191   1.263
113   L        -0.460  -0.680  -0.752  -0.623  -0.946  -1.062  -0.450  -0.732  -0.826
114   V        -0.773  -0.814  -0.764  -0.934  -0.966  -0.915  -0.889  -0.913  -0.845
115   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
116   T         1.102   1.124   1.172   1.042   1.079   1.160   1.162   1.191   1.263
117   S        -1.403  -1.399  -1.305  -1.571  -1.586  -1.417  -1.329  -1.310  -1.151
118   L        -0.072  -0.074  -0.067  -0.464  -0.471  -0.457  -0.303  -0.313  -0.337
119   S         1.102   1.124   1.172   1.100   1.127   1.211   1.162   1.191   1.263
120   L        -1.938  -1.929  -1.735  -2.088  -2.041  -1.726  -1.622  -1.583  -1.339
121   T        -0.460  -0.680  -0.752  -0.331  -0.635  -0.744  -0.450  -0.732  -0.826
122   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
123   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
124   L        -1.403  -1.439  -1.306  -1.669  -1.720  -1.518  -1.329  -1.343  -1.152
125   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
126   M        -0.460  -0.680  -0.752  -0.140  -0.499  -0.735  -0.450  -0.732  -0.826
127   V        -1.403  -1.345  -1.297  -1.467  -1.390  -1.262  -1.329  -1.256  -1.144
128   E         1.102   1.124   1.172   1.281   1.311   1.373   1.162   1.191   1.263
129   Q         1.102   1.124   1.172   1.252   1.285   1.347   1.162   1.191   1.263
130   L         0.297   0.352   0.039   0.093   0.174  -0.271   0.283   0.360  -0.151
131   V        -1.938  -1.929  -1.733  -2.138  -2.165  -1.866  -1.622  -1.583  -1.337
132   P         1.102   1.124   1.172   1.162   1.190   1.267   1.162   1.191   1.263
133   I        -0.238  -0.220  -0.084  -0.330  -0.351  -0.140  -0.596  -0.572  -0.367
134   I         0.297   0.156   0.024   0.256   0.060  -0.162   0.283   0.067  -0.176
135   V        -0.868  -0.749  -0.771  -1.088  -0.915  -0.924  -1.036  -0.889  -0.856
136   Q        -0.868  -0.748  -0.773  -0.714  -0.565  -0.560  -1.036  -0.888  -0.858
137   H        -0.460  -0.680  -0.752  -0.094  -0.398  -0.553  -0.450  -0.732  -0.826
138   G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
139   L        -0.072  -0.166  -0.074  -0.464  -0.638  -0.468  -0.303  -0.475  -0.349
140   Y        -0.773  -0.750  -0.751  -0.941  -0.901  -0.937  -0.889  -0.829  -0.827
141   F        -0.773  -0.814  -0.764  -0.793  -0.816  -0.764  -0.889  -0.913  -0.845
142   A         0.297   0.352   0.039   0.377   0.447  -0.017   0.283   0.360  -0.151
143   I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
144   C         1.102   1.124   1.172   1.332   1.361   1.419   1.162   1.191   1.263
145   N        -1.014  -1.005  -0.818  -0.841  -0.823  -0.573  -1.182  -1.158  -0.910
146   I        -1.403  -1.269  -1.286  -1.391  -1.238  -1.178  -1.329  -1.184  -1.134
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   G        -0.460  -0.380  -0.714  -0.224  -0.122  -0.585  -0.450  -0.341  -0.777
149   A        -0.460  -0.680  -0.752  -0.298  -0.617  -0.744  -0.450  -0.732  -0.826
150   W         1.102   1.124   1.172   1.294   1.321   1.385   1.162   1.191   1.263
151   T         0.297   0.350   0.043   0.336   0.410  -0.031   0.283   0.358  -0.145
152   Q         1.102   1.124   1.172   1.252   1.285   1.347   1.162   1.191   1.263
153   P         0.297   0.350   0.043   0.485   0.550   0.138   0.283   0.358  -0.145
154   L        -0.460  -0.424  -0.709  -0.551  -0.527  -0.852  -0.450  -0.411  -0.771
155   V         0.297   0.352   0.039   0.248   0.340  -0.140   0.283   0.360  -0.151
156   T        -1.161  -1.313  -1.299  -1.017  -1.264  -1.237  -1.036  -1.196  -1.143
157   L         0.297   0.199   0.029   0.156   0.051  -0.139   0.283   0.134  -0.168
158   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
159   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
160   M        -0.072   0.086  -0.009  -0.321  -0.096  -0.188  -0.303  -0.045  -0.234
161   N         1.102   1.124   1.172   1.265   1.303   1.359   1.162   1.191   1.263
162   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
163   I        -0.238  -0.218  -0.083  -0.727  -0.727  -0.479  -0.596  -0.569  -0.365
164   V        -0.072   0.086  -0.009  -0.253   0.018  -0.176  -0.303  -0.045  -0.234
165   K         1.102   1.124   1.172   1.153   1.192   1.259   1.162   1.191   1.263
166   F        -0.072  -0.166  -0.074  -0.244  -0.417  -0.266  -0.303  -0.475  -0.349
167   I        -1.161  -1.313  -1.299  -1.187  -1.470  -1.478  -1.036  -1.196  -1.143
168   E         1.102   1.124   1.172   1.281   1.311   1.373   1.162   1.191   1.263
169   F        -0.072  -0.166  -0.074  -0.350  -0.565  -0.429  -0.303  -0.475  -0.349
170   I        -0.072  -0.113  -0.068  -0.368  -0.471  -0.430  -0.303  -0.382  -0.339
171   D         1.102   1.124   1.172   1.312   1.339   1.401   1.162   1.191   1.263
172   T         1.102   1.124   1.172   1.042   1.079   1.160   1.162   1.191   1.263
173   F        -1.791  -1.637  -1.700  -1.781  -1.500  -1.678  -1.475  -1.319  -1.311
174   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
175   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
176   V         0.297   0.156   0.024   0.251   0.075  -0.159   0.283   0.067  -0.176
177   L        -0.072  -0.013  -0.042  -0.468  -0.361  -0.418  -0.303  -0.209  -0.292
178   K         0.297   0.199   0.029   0.468   0.352   0.090   0.283   0.134  -0.168
179   H        -1.014  -0.988  -0.818  -0.923  -0.898  -0.664  -1.182  -1.137  -0.910
180   K         1.102   1.124   1.172   1.153   1.192   1.259   1.162   1.191   1.263
181   K         0.297   0.156   0.024   0.456   0.278   0.054   0.283   0.067  -0.176
182   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
183   T         1.102   1.124   1.172   1.042   1.079   1.160   1.162   1.191   1.263
184   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
185   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
186   H         1.102   1.124   1.172   1.272   1.308   1.365   1.162   1.191   1.263
187   T         0.297   0.156   0.024   0.376   0.210   0.034   0.283   0.067  -0.176
188   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
189   H         1.102   1.124   1.172   1.272   1.308   1.365   1.162   1.191   1.263
190   H         1.102   1.124   1.172   1.272   1.308   1.365   1.162   1.191   1.263
191   G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
192   A         1.102   1.124   1.172   1.093   1.121   1.205   1.162   1.191   1.263
193   T         1.102   1.124   1.172   1.042   1.079   1.160   1.162   1.191   1.263
194   A         1.102   1.124   1.172   1.093   1.121   1.205   1.162   1.191   1.263
195   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
196   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
197   C         1.102   1.124   1.172   1.332   1.361   1.419   1.162   1.191   1.263
198   Y         0.297   0.422   0.045   0.373   0.533  -0.019   0.283   0.459  -0.141
199   T         1.102   1.124   1.172   1.042   1.079   1.160   1.162   1.191   1.263
200   Q         1.102   1.124   1.172   1.252   1.285   1.347   1.162   1.191   1.263
201   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
202   M        -0.868  -0.736  -0.775  -1.083  -0.896  -0.856  -1.036  -0.869  -0.860
203   G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
204   T        -1.161  -1.313  -1.299  -1.075  -1.302  -1.340  -1.036  -1.196  -1.143
205   T         1.102   1.124   1.172   1.042   1.079   1.160   1.162   1.191   1.263
206   S        -0.460  -0.316  -0.700  -0.287  -0.104  -0.646  -0.450  -0.260  -0.759
207   I        -0.072  -0.166  -0.074  -0.310  -0.494  -0.352  -0.303  -0.475  -0.349
208   S         1.102   1.124   1.172   1.100   1.127   1.211   1.162   1.191   1.263
209   W         1.102   1.124   1.172   1.294   1.321   1.385   1.162   1.191   1.263
210   V         1.102   1.124   1.172   0.974   1.025   1.099   1.162   1.191   1.263
211   P         1.102   1.124   1.172   1.162   1.190   1.267   1.162   1.191   1.263
212   I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
213   S        -0.238  -0.218  -0.083  -0.488  -0.474  -0.250  -0.596  -0.569  -0.365
214   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
215   N         1.102   1.124   1.172   1.265   1.303   1.359   1.162   1.191   1.263
216   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
217   G        -1.161  -1.311  -1.299  -0.970  -1.231  -1.251  -1.036  -1.195  -1.143
218   V         1.102   1.124   1.172   0.974   1.025   1.099   1.162   1.191   1.263
219   H         1.102   1.124   1.172   1.272   1.308   1.365   1.162   1.191   1.263
220   V         0.297   0.350   0.043   0.308   0.395   0.005   0.283   0.358  -0.145
221   V         0.297   0.352   0.039   0.221   0.316  -0.204   0.283   0.360  -0.151
222   M         1.102   1.124   1.172   1.332   1.360   1.419   1.162   1.191   1.263
223   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
224   W         0.297   0.199   0.029   0.571   0.431   0.117   0.283   0.134  -0.168
225   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
226   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
227   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
228   L         0.297   0.156   0.024   0.141  -0.024  -0.180   0.283   0.067  -0.176
229   A         0.297   0.156   0.024   0.387   0.193  -0.020   0.283   0.067  -0.176
230   A         1.102   1.124   1.172   1.093   1.121   1.205   1.162   1.191   1.263
231   R         1.102   1.124   1.172   1.232   1.254   1.329   1.162   1.191   1.263
232   G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
233   I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
234   R         1.102   1.124   1.172   1.232   1.254   1.329   1.162   1.191   1.263
235   V         0.297   0.156   0.024   0.248   0.069  -0.167   0.283   0.067  -0.176
236   W         1.102   1.124   1.172   1.294   1.321   1.385   1.162   1.191   1.263
237   W         1.102   1.124   1.172   1.294   1.321   1.385   1.162   1.191   1.263
238   K         1.102   1.124   1.172   1.153   1.192   1.259   1.162   1.191   1.263
239   E         1.102   1.124   1.172   1.281   1.311   1.373   1.162   1.191   1.263
240   W         1.102   1.124   1.172   1.294   1.321   1.385   1.162   1.191   1.263
241   V         0.297   0.156   0.024   0.248   0.069  -0.167   0.283   0.067  -0.176
242   T         1.102   1.124   1.172   1.042   1.079   1.160   1.162   1.191   1.263
243   R         1.102   1.124   1.172   1.232   1.254   1.329   1.162   1.191   1.263
244   F        -0.072  -0.166  -0.074  -0.350  -0.565  -0.429  -0.303  -0.475  -0.349
245   Q         1.102   1.124   1.172   1.252   1.285   1.347   1.162   1.191   1.263
246   I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
247   I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
248   Q         1.102   1.124   1.172   1.252   1.285   1.347   1.162   1.191   1.263
249   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
250   V        -0.238  -0.208  -0.084  -0.631  -0.576  -0.374  -0.596  -0.550  -0.367
251   L        -0.868  -0.737  -0.773  -1.293  -1.067  -1.088  -1.036  -0.870  -0.858
252   D         1.102   1.124   1.172   1.312   1.339   1.401   1.162   1.191   1.263
253   I        -0.238  -0.124  -0.057  -0.762  -0.562  -0.440  -0.596  -0.400  -0.319
254   G        -0.460  -0.315  -0.704  -0.242  -0.060  -0.606  -0.450  -0.258  -0.764
255   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
256   I        -0.238  -0.124  -0.057  -0.631  -0.407  -0.320  -0.596  -0.400  -0.319
257   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
258   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
259   A         0.297   0.352   0.039   0.392   0.460   0.019   0.283   0.360  -0.151
260   V        -1.014  -0.988  -0.818  -1.285  -1.220  -0.967  -1.182  -1.137  -0.910
261   Y         0.297   0.422   0.045   0.422   0.571   0.092   0.283   0.459  -0.141
262   Q        -0.072  -0.166  -0.074  -0.027  -0.223  -0.116  -0.303  -0.475  -0.349
263   K        -0.072  -0.166  -0.074  -0.101  -0.280  -0.158  -0.303  -0.475  -0.349
264   A        -1.549  -1.443  -1.326  -1.765  -1.597  -1.427  -1.475  -1.344  -1.170
265   V        -0.868  -0.752  -0.771  -1.101  -0.922  -0.908  -1.036  -0.895  -0.857
266   H        -1.938  -1.783  -1.728  -1.803  -1.595  -1.559  -1.622  -1.457  -1.333
267   L        -0.773  -0.552  -0.743  -0.914  -0.556  -0.823  -0.889  -0.588  -0.816
268   Y         0.297   0.352   0.039   0.418   0.489   0.075   0.283   0.360  -0.151
269   F         0.297   0.199   0.029   0.330   0.213  -0.007   0.283   0.134  -0.168
270   P        -0.072  -0.013  -0.042  -0.091  -0.004  -0.085  -0.303  -0.209  -0.292
271   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
272   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
273   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   I        -1.938  -1.747  -1.722  -1.836  -1.515  -1.549  -1.622  -1.434  -1.329
276   L        -0.072  -0.166  -0.074  -0.321  -0.436  -0.252  -0.303  -0.475  -0.349
277   P         1.102   1.124   1.172   1.162   1.190   1.267   1.162   1.191   1.263
278   H        -1.403  -1.355  -1.317  -1.164  -1.096  -1.100  -1.329  -1.269  -1.162
279   C        -0.460  -0.680  -0.752  -0.028  -0.340  -0.494  -0.450  -0.732  -0.826
280   G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
281   D        -1.403  -1.381  -1.305  -1.125  -1.131  -1.007  -1.329  -1.295  -1.151
282   C         1.102   1.124   1.172   1.332   1.361   1.419   1.162   1.191   1.263
283   V        -0.238  -0.124  -0.057  -0.536  -0.312  -0.233  -0.596  -0.400  -0.319
284   G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
285   S        -1.014  -0.988  -0.818  -1.091  -1.026  -0.791  -1.182  -1.137  -0.910
286   T        -1.014  -0.988  -0.818  -0.988  -0.919  -0.674  -1.182  -1.137  -0.910
287   T        -1.403  -1.355  -1.317  -1.580  -1.529  -1.500  -1.329  -1.269  -1.162
288   A         1.102   1.124   1.172   1.093   1.121   1.205   1.162   1.191   1.263
289   T        -0.238  -0.124  -0.057  -0.494  -0.287  -0.197  -0.596  -0.400  -0.319
290   F        -0.773  -0.809  -0.769  -0.903  -0.956  -0.904  -0.889  -0.912  -0.851
291   A        -0.773  -0.735  -0.746  -0.789  -0.713  -0.750  -0.889  -0.808  -0.820
292   G         1.102   1.124   1.172   1.134   1.161   1.242   1.162   1.191   1.263
293   C         0.297   0.156   0.024   0.606   0.402   0.132   0.283   0.067  -0.176
294   A        -0.072  -0.166  -0.074  -0.143  -0.323  -0.178  -0.303  -0.475  -0.349
295   I         0.297   0.199   0.029   0.231   0.086  -0.216   0.283   0.134  -0.168
296   I        -0.238  -0.124  -0.057  -0.762  -0.562  -0.440  -0.596  -0.400  -0.319
297   S         0.297   0.199   0.029   0.384   0.249  -0.029   0.283   0.134  -0.168
298   S         1.102   1.124   1.172   1.100   1.127   1.211   1.162   1.191   1.263
299   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
300   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
301   V        -0.072  -0.062  -0.060  -0.308  -0.283  -0.317  -0.303  -0.293  -0.325
302   L         1.102   1.124   1.172   0.820   0.860   0.961   1.162   1.191   1.263
303   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
304   I         1.102   1.124   1.172   0.983   1.012   1.107   1.162   1.191   1.263
305   S        -0.238  -0.198  -0.081  -0.458  -0.403  -0.211  -0.596  -0.533  -0.361
306   F         1.102   1.124   1.172   1.002   1.035   1.124   1.162   1.191   1.263
307   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
308   I        -0.460  -0.554  -0.724  -0.385  -0.534  -0.739  -0.450  -0.574  -0.790
309   N        -1.403  -1.409  -1.303  -1.075  -1.091  -0.948  -1.329  -1.308  -1.149
310   V        -0.460  -0.680  -0.752  -0.435  -0.735  -0.872  -0.450  -0.732  -0.826
311   Y         1.102   1.124   1.172   1.095   1.127   1.207   1.162   1.191   1.263
312   K        -0.238  -0.205  -0.083  -0.328  -0.279  -0.093  -0.596  -0.544  -0.365
313   R        -0.238  -0.218  -0.083  -0.312  -0.301  -0.093  -0.596  -0.569  -0.365
314   K        -1.161  -1.262  -1.293  -0.812  -0.954  -0.992  -1.036  -1.146  -1.137
315   G        -0.600  -0.656  -0.747  -0.407  -0.499  -0.636  -0.633  -0.702  -0.820
316   T        -0.773  -0.783  -0.756  -0.799  -0.782  -0.770  -0.889  -0.870  -0.833
317   K        -0.460  -0.552  -0.727  -0.231  -0.351  -0.643  -0.450  -0.572  -0.794
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   T        -1.938  -1.857  -1.717  -1.770  -1.664  -1.451  -1.622  -1.527  -1.325
320   S         0.297   0.156   0.024   0.399   0.207  -0.000   0.283   0.067  -0.176
321   R        -0.238  -0.198  -0.081  -0.328  -0.268  -0.090  -0.596  -0.533  -0.361
322   V        -1.335  -1.400  -1.323  -1.364  -1.452  -1.333  -1.231  -1.292  -1.166
323   V         0.218   0.256   0.008   0.113   0.173  -0.217   0.165   0.220  -0.204
324   K         0.297   0.199   0.029   0.426   0.301  -0.011   0.283   0.134  -0.168
325   R        -1.014  -1.005  -0.818  -1.057  -1.082  -0.799  -1.182  -1.158  -0.910
326   A        -0.460  -0.490  -0.715  -0.480  -0.539  -0.905  -0.450  -0.498  -0.778
327   H        -1.938  -1.892  -1.719  -1.502  -1.433  -1.216  -1.622  -1.549  -1.327
328   G         0.297   0.156   0.024   0.450   0.263   0.067   0.283   0.067  -0.176
329   G        -0.460  -0.680  -0.752  -0.206  -0.500  -0.606  -0.450  -0.732  -0.826
330   V         0.297   0.156   0.024   0.268   0.098  -0.118   0.283   0.067  -0.176
331   A        -0.460  -0.680  -0.752  -0.268  -0.569  -0.680  -0.450  -0.732  -0.826
332   A         0.297   0.199   0.029   0.392   0.261   0.002   0.283   0.134  -0.168
333   K        -0.882  -0.969  -0.804  -0.830  -0.946  -0.710  -1.032  -1.114  -0.894
334   V         0.218   0.018  -0.017   0.107  -0.198  -0.322   0.165  -0.156  -0.249
335   N         0.218   0.018  -0.017   0.467   0.180   0.072   0.165  -0.156  -0.249
336   E         0.218   0.018  -0.017   0.507   0.227   0.146   0.165  -0.156  -0.249
337   Y         0.218   0.018  -0.017   0.293   0.008  -0.066   0.165  -0.156  -0.249
338   V         0.218   0.018  -0.017   0.172  -0.091  -0.172   0.165  -0.156  -0.249
339   N        -0.882  -0.969  -0.804  -0.679  -0.780  -0.566  -1.032  -1.114  -0.894
340   V        -0.882  -0.969  -0.804  -1.103  -1.229  -0.975  -1.032  -1.114  -0.894
341   D        -1.335  -1.406  -1.323  -1.087  -1.258  -1.197  -1.231  -1.301  -1.166
342   L        -0.882  -0.969  -0.804  -1.172  -1.276  -0.987  -1.032  -1.114  -0.894
343   K        -1.506  -1.437  -1.317  -1.504  -1.422  -1.216  -1.431  -1.342  -1.162
344   N        -1.161  -1.207  -1.281  -0.729  -0.804  -0.938  -1.036  -1.081  -1.125
345   V        -1.403  -1.355  -1.317  -1.505  -1.424  -1.361  -1.329  -1.269  -1.162
346   P        -1.403  -1.386  -1.296  -1.227  -1.194  -1.038  -1.329  -1.283  -1.143
347   T        -0.460  -0.552  -0.727  -0.348  -0.478  -0.743  -0.450  -0.572  -0.794
348   P        -1.161  -1.311  -1.299  -0.859  -1.099  -1.086  -1.036  -1.195  -1.143
349   S        -1.403  -1.501  -1.323  -1.358  -1.487  -1.222  -1.329  -1.395  -1.167
350   P        -0.460  -0.515  -0.720  -0.205  -0.289  -0.589  -0.450  -0.520  -0.785
351   S        -0.460  -0.516  -0.719  -0.296  -0.372  -0.695  -0.450  -0.522  -0.783
352   P        -0.773  -0.798  -0.787  -0.726  -0.807  -0.781  -0.889  -0.937  -0.875
353   K        -1.791  -1.659  -1.689  -1.510  -1.320  -1.378  -1.475  -1.336  -1.301
354   P        -1.403  -1.364  -1.288  -1.334  -1.276  -1.168  -1.329  -1.257  -1.134
355   Q        -1.403  -1.168  -1.288  -1.273  -0.968  -1.085  -1.329  -1.066  -1.134
356   -        -2.412  -2.325  -2.075  -2.264  -2.148  -1.799  -1.830  -1.731  -1.455
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   H         0.297   0.423   0.050   0.553   0.697   0.203   0.283   0.461  -0.132
361   R        -0.072   0.086  -0.009  -0.099   0.131  -0.014  -0.303  -0.045  -0.234
362   R         0.297   0.422   0.045   0.533   0.681   0.151   0.283   0.459  -0.141
363   K         0.297   0.199   0.029   0.468   0.352   0.090   0.283   0.134  -0.168
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   R        -0.072   0.086  -0.009  -0.106   0.125  -0.019  -0.303  -0.045  -0.234
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25358
Output conservation file - output/P25358
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
