1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    M         0.270   0.166  -0.051   0.574   0.425   0.009   0.282   0.129  -0.247
64    S         0.270   0.166  -0.051   0.479   0.357   0.058   0.282   0.129  -0.247
65    W         0.270   0.166  -0.051   0.672   0.528   0.092   0.282   0.129  -0.247
66    E        -2.244  -2.338  -2.150  -1.914  -2.025  -1.753  -1.732  -1.792  -1.540
67    G         1.004   1.018   1.092   1.122   1.144   1.247   1.065   1.084   1.194
68    F         1.004   1.018   1.092   1.183   1.202   1.302   1.065   1.084   1.194
69    K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
70    K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
71    A         0.270   0.166  -0.051   0.281   0.153  -0.139   0.282   0.129  -0.247
72    I        -0.894  -0.902  -0.859  -0.871  -0.888  -0.776  -1.061  -1.066  -0.950
73    N         0.270   0.270  -0.046   0.583   0.588   0.153   0.282   0.282  -0.238
74    R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
75    A         1.004   1.018   1.092   0.892   0.908   1.038   1.065   1.084   1.194
76    G         0.270   0.166  -0.051   0.495   0.365   0.008   0.282   0.129  -0.247
77    H        -1.569  -1.432  -1.404  -1.484  -1.316  -1.217  -1.508  -1.361  -1.255
78    S         0.270   0.166  -0.051   0.444   0.312  -0.040   0.282   0.129  -0.247
79    V         1.004   1.018   1.092   1.053   1.067   1.184   1.065   1.084   1.194
80    I        -1.442  -1.365  -1.393  -1.274  -1.141  -1.247  -1.397  -1.306  -1.245
81    I        -1.104  -1.057  -0.893  -1.080  -0.990  -0.789  -1.285  -1.215  -0.989
82    K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    N        -1.442  -1.396  -1.397  -1.176  -1.086  -1.186  -1.397  -1.329  -1.248
86    V         1.004   1.018   1.092   1.053   1.067   1.184   1.065   1.084   1.194
87    D        -0.285  -0.314  -0.163  -0.612  -0.677  -0.435  -0.613  -0.670  -0.445
88    K         0.270   0.190  -0.052   0.208   0.117  -0.244   0.282   0.165  -0.248
89    T         1.004   1.018   1.092   1.071   1.084   1.201   1.065   1.084   1.194
90    I        -1.907  -1.915  -1.807  -1.547  -1.570  -1.366  -1.620  -1.618  -1.421
91    D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
92    K        -0.285  -0.314  -0.163  -0.624  -0.672  -0.424  -0.613  -0.670  -0.445
93    E        -0.346  -0.325  -0.164  -0.734  -0.699  -0.437  -0.725  -0.690  -0.447
94    Y        -0.346  -0.321  -0.163  -0.420  -0.373  -0.148  -0.725  -0.683  -0.446
95    D        -0.894  -0.841  -0.870  -1.108  -1.057  -1.012  -1.061  -1.011  -0.963
96    M        -1.104  -1.085  -0.887  -1.094  -1.094  -0.808  -1.285  -1.251  -0.981
97    E         1.004   1.018   1.092   0.942   0.956   1.083   1.065   1.084   1.194
98    E         1.004   1.018   1.092   0.942   0.956   1.083   1.065   1.084   1.194
99    R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
100   R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
101   Y        -0.092  -0.087  -0.138  -0.000   0.008  -0.112  -0.278  -0.272  -0.401
102   K        -0.346  -0.325  -0.165  -0.716  -0.685  -0.424  -0.725  -0.691  -0.448
103   V        -0.285  -0.174  -0.120  -0.410  -0.220  -0.168  -0.613  -0.420  -0.369
104   L        -0.285  -0.314  -0.163  -0.523  -0.551  -0.300  -0.613  -0.670  -0.445
105   Q        -1.359  -1.254  -1.361  -1.379  -1.209  -1.412  -1.285  -1.142  -1.211
106   R        -2.034  -1.994  -1.803  -2.071  -2.004  -1.729  -1.732  -1.684  -1.418
107   A         1.004   1.018   1.092   0.892   0.908   1.038   1.065   1.084   1.194
108   G        -0.750  -0.867  -0.865  -0.628  -0.818  -0.881  -0.837  -0.985  -0.955
109   E        -1.569  -1.563  -1.392  -1.756  -1.743  -1.536  -1.508  -1.479  -1.244
110   A        -2.709  -2.606  -2.429  -2.549  -2.402  -2.143  -1.956  -1.870  -1.619
111   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
112   Q         0.270   0.266  -0.044   0.439   0.438   0.004   0.282   0.276  -0.234
113   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
114   E        -0.092  -0.078  -0.116  -0.247  -0.233  -0.342  -0.278  -0.257  -0.360
115   A         0.270   0.270  -0.046   0.265   0.264  -0.174   0.282   0.282  -0.238
116   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
117   G         1.004   1.018   1.092   1.122   1.144   1.247   1.065   1.084   1.194
118   F        -0.092  -0.032  -0.130  -0.000   0.091  -0.097  -0.278  -0.181  -0.385
119   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
120   D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
121   S        -0.429  -0.490  -0.796  -0.181  -0.268  -0.750  -0.389  -0.466  -0.863
122   L         0.270   0.296  -0.042   0.203   0.243  -0.217   0.282   0.319  -0.232
123   R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
124   A         1.004   1.018   1.092   0.892   0.908   1.038   1.065   1.084   1.194
125   V        -0.894  -0.883  -0.872  -0.818  -0.798  -0.762  -1.061  -1.048  -0.964
126   T         1.004   1.018   1.092   1.071   1.084   1.201   1.065   1.084   1.194
127   A        -0.429  -0.420  -0.788  -0.332  -0.322  -0.808  -0.389  -0.375  -0.852
128   S         1.004   1.018   1.092   1.074   1.092   1.203   1.065   1.084   1.194
129   Q         1.004   1.018   1.092   1.051   1.071   1.182   1.065   1.084   1.194
130   T        -0.894  -0.958  -0.861  -0.887  -0.963  -0.788  -1.061  -1.115  -0.953
131   T        -0.285  -0.314  -0.163  -0.421  -0.498  -0.264  -0.613  -0.670  -0.445
132   I         1.004   1.018   1.092   1.087   1.114   1.215   1.065   1.084   1.194
133   A         0.270   0.270  -0.046   0.265   0.264  -0.174   0.282   0.282  -0.238
134   E         0.270   0.190  -0.052   0.331   0.232  -0.099   0.282   0.165  -0.248
135   V        -1.104  -1.057  -0.893  -1.197  -1.120  -0.890  -1.285  -1.215  -0.989
136   I         0.270   0.270  -0.046   0.457   0.466  -0.019   0.282   0.282  -0.238
137   S        -0.894  -0.883  -0.872  -0.996  -1.005  -0.939  -1.061  -1.048  -0.964
138   N        -0.894  -0.841  -0.870  -0.959  -0.931  -0.959  -1.061  -1.011  -0.963
139   L        -0.285  -0.314  -0.163  -0.553  -0.581  -0.335  -0.613  -0.670  -0.445
140   Y         1.004   1.018   1.092   1.099   1.120   1.226   1.065   1.084   1.194
141   D        -1.104  -1.057  -0.893  -1.323  -1.213  -1.007  -1.285  -1.215  -0.989
142   D        -0.285  -0.296  -0.163  -0.612  -0.642  -0.434  -0.613  -0.638  -0.445
143   S        -0.346  -0.305  -0.156  -0.648  -0.597  -0.354  -0.725  -0.655  -0.433
144   K         1.004   1.018   1.092   0.801   0.822   0.955   1.065   1.084   1.194
145   Y        -1.051  -0.992  -0.894  -1.170  -1.075  -0.969  -1.226  -1.144  -0.990
146   V        -1.591  -1.450  -1.415  -1.489  -1.270  -1.269  -1.513  -1.350  -1.264
147   A        -1.051  -1.064  -0.890  -1.231  -1.254  -0.990  -1.226  -1.228  -0.985
148   G        -0.750  -0.672  -0.837  -0.628  -0.521  -0.825  -0.837  -0.743  -0.918
149   G        -2.371  -2.379  -2.140  -2.171  -2.198  -1.903  -1.844  -1.827  -1.534
150   G        -2.034  -1.961  -1.816  -2.023  -1.943  -1.738  -1.732  -1.656  -1.428
151   Y        -1.569  -1.440  -1.403  -1.554  -1.388  -1.257  -1.508  -1.365  -1.253
152   N        -0.285  -0.314  -0.163  -0.282  -0.345  -0.136  -0.613  -0.670  -0.445
153   V        -0.092  -0.045  -0.132  -0.075  -0.007  -0.186  -0.278  -0.203  -0.389
154   G        -0.285  -0.314  -0.163  -0.355  -0.420  -0.203  -0.613  -0.670  -0.445
155   N        -1.359  -1.436  -1.394  -1.236  -1.398  -1.385  -1.285  -1.363  -1.246
156   Y         0.270   0.166  -0.051   0.473   0.343  -0.010   0.282   0.129  -0.247
157   Y         1.004   1.018   1.092   1.099   1.120   1.226   1.065   1.084   1.194
158   L        -1.696  -1.822  -1.789  -1.604  -1.798  -1.720  -1.397  -1.509  -1.405
159   Q         1.004   1.018   1.092   1.051   1.071   1.182   1.065   1.084   1.194
160   C        -1.359  -1.436  -1.394  -1.073  -1.237  -1.220  -1.285  -1.363  -1.246
161   V         1.004   1.018   1.092   1.053   1.067   1.184   1.065   1.084   1.194
162   Q        -1.569  -1.533  -1.404  -1.719  -1.699  -1.480  -1.508  -1.472  -1.255
163   D        -0.092  -0.080  -0.133  -0.261  -0.241  -0.377  -0.278  -0.261  -0.392
164   F        -0.346  -0.305  -0.156  -0.612  -0.573  -0.333  -0.725  -0.655  -0.433
165   D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
166   S        -1.569  -1.432  -1.404  -1.712  -1.536  -1.444  -1.508  -1.361  -1.255
167   E         0.270   0.190  -0.052   0.292   0.184  -0.209   0.282   0.165  -0.248
168   T         1.004   1.018   1.092   1.071   1.084   1.201   1.065   1.084   1.194
169   V         0.270   0.166  -0.051   0.429   0.295  -0.043   0.282   0.129  -0.247
170   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
171   Q        -0.750  -0.867  -0.865  -0.755  -0.959  -1.008  -0.837  -0.985  -0.955
172   L        -0.429  -0.417  -0.800  -0.415  -0.393  -0.921  -0.389  -0.370  -0.869
173   D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
174   G         1.004   1.018   1.092   1.122   1.144   1.247   1.065   1.084   1.194
175   P         1.004   1.018   1.092   1.203   1.218   1.320   1.065   1.084   1.194
176   L        -0.894  -0.819  -0.850  -0.846  -0.756  -0.821  -1.061  -0.987  -0.940
177   R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
178   E        -0.092  -0.186  -0.134  -0.188  -0.354  -0.283  -0.278  -0.443  -0.393
179   T         1.004   1.018   1.092   1.071   1.084   1.201   1.065   1.084   1.194
180   V         0.270   0.270  -0.046   0.429   0.427  -0.034   0.282   0.282  -0.238
181   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
182   D         0.270   0.359  -0.041   0.265   0.381  -0.203   0.282   0.406  -0.229
183   P         1.004   1.018   1.092   1.203   1.218   1.320   1.065   1.084   1.194
184   I         0.270   0.402  -0.034   0.457   0.621   0.002   0.282   0.463  -0.218
185   T        -0.429  -0.490  -0.796  -0.163  -0.248  -0.705  -0.389  -0.466  -0.863
186   K        -0.285  -0.314  -0.163  -0.624  -0.672  -0.424  -0.613  -0.670  -0.445
187   F         1.004   1.018   1.092   1.183   1.202   1.302   1.065   1.084   1.194
188   S        -1.569  -1.473  -1.404  -1.426  -1.231  -1.222  -1.508  -1.386  -1.254
189   T        -1.569  -1.611  -1.414  -1.543  -1.618  -1.327  -1.508  -1.531  -1.264
190   Y         1.004   1.018   1.092   1.099   1.120   1.226   1.065   1.084   1.194
191   F         1.004   1.018   1.092   1.183   1.202   1.302   1.065   1.084   1.194
192   K        -2.034  -1.950  -1.808  -1.972  -1.800  -1.644  -1.732  -1.648  -1.421
193   E        -0.285  -0.314  -0.163  -0.601  -0.673  -0.433  -0.613  -0.670  -0.445
194   I         0.270   0.166  -0.051   0.457   0.332  -0.028   0.282   0.129  -0.247
195   E        -1.104  -1.027  -0.892  -1.284  -1.129  -0.978  -1.285  -1.185  -0.987
196   E        -0.429  -0.433  -0.794  -0.331  -0.352  -0.894  -0.389  -0.397  -0.861
197   A         0.270   0.166  -0.051   0.299   0.176  -0.090   0.282   0.129  -0.247
198   I         1.004   1.018   1.092   1.087   1.114   1.215   1.065   1.084   1.194
199   K         0.270   0.190  -0.052   0.214   0.124  -0.228   0.282   0.165  -0.248
200   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
201   R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
202   D        -2.034  -1.994  -1.817  -2.021  -1.929  -1.703  -1.732  -1.683  -1.428
203   H         1.004   1.018   1.092   1.301   1.318   1.410   1.065   1.084   1.194
204   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
205   K        -0.285  -0.314  -0.163  -0.738  -0.803  -0.559  -0.613  -0.670  -0.445
206   Q        -2.371  -2.287  -2.146  -2.270  -2.156  -1.937  -1.844  -1.762  -1.538
207   D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
208   F        -0.429  -0.410  -0.789  -0.088  -0.063  -0.563  -0.389  -0.369  -0.854
209   D         0.270   0.296  -0.042   0.265   0.305  -0.206   0.282   0.319  -0.232
210   A        -0.092  -0.078  -0.116  -0.243  -0.226  -0.302  -0.278  -0.257  -0.360
211   A        -1.569  -1.611  -1.414  -1.606  -1.652  -1.322  -1.508  -1.531  -1.264
212   K        -0.285  -0.314  -0.163  -0.624  -0.672  -0.424  -0.613  -0.670  -0.445
213   A         0.270   0.266  -0.044   0.300   0.295  -0.076   0.282   0.276  -0.234
214   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
215   V         0.270   0.266  -0.044   0.426   0.418  -0.036   0.282   0.276  -0.234
216   R        -0.750  -0.867  -0.865  -0.770  -0.971  -1.001  -0.837  -0.985  -0.955
217   R        -0.346  -0.305  -0.156  -0.716  -0.659  -0.416  -0.725  -0.655  -0.433
218   L         0.270   0.402  -0.034   0.226   0.378  -0.143   0.282   0.463  -0.218
219   V        -0.285  -0.218  -0.148  -0.408  -0.294  -0.215  -0.613  -0.498  -0.418
220   D        -0.092  -0.151  -0.127  -0.261  -0.365  -0.365  -0.278  -0.381  -0.381
221   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
222   P         1.004   1.018   1.092   1.203   1.218   1.320   1.065   1.084   1.194
223   A        -0.750  -0.876  -0.865  -0.844  -1.036  -1.032  -0.837  -0.992  -0.955
224   K        -0.092  -0.138  -0.125  -0.249  -0.311  -0.290  -0.278  -0.359  -0.378
225   D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
226   A        -0.429  -0.606  -0.810  -0.354  -0.593  -0.893  -0.389  -0.616  -0.882
227   S        -1.569  -1.499  -1.386  -1.584  -1.474  -1.319  -1.508  -1.418  -1.238
228   K         0.270   0.266  -0.044   0.208   0.214  -0.230   0.282   0.276  -0.234
229   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
230   P         1.004   1.018   1.092   1.203   1.218   1.320   1.065   1.084   1.194
231   R         0.270   0.266  -0.044   0.403   0.394  -0.061   0.282   0.276  -0.234
232   A         0.270   0.190  -0.052   0.265   0.162  -0.185   0.282   0.165  -0.248
233   E         1.004   1.018   1.092   0.942   0.956   1.083   1.065   1.084   1.194
234   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
235   E         1.004   1.018   1.092   0.942   0.956   1.083   1.065   1.084   1.194
236   L        -1.359  -1.424  -1.382  -1.405  -1.498  -1.417  -1.285  -1.340  -1.235
237   S        -1.442  -1.492  -1.385  -1.508  -1.577  -1.413  -1.397  -1.424  -1.238
238   L        -0.894  -0.779  -0.850  -0.893  -0.695  -0.789  -1.061  -0.910  -0.937
239   A         1.004   1.018   1.092   0.892   0.908   1.038   1.065   1.084   1.194
240   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
241   D        -0.894  -0.963  -0.864  -1.158  -1.255  -1.098  -1.061  -1.123  -0.955
242   I        -1.087  -1.255  -1.376  -0.763  -1.004  -1.230  -0.949  -1.134  -1.226
243   F        -0.092  -0.029  -0.118  -0.000   0.095  -0.077  -0.278  -0.177  -0.364
244   E        -0.894  -0.877  -0.856  -1.112  -1.077  -1.009  -1.061  -1.026  -0.945
245   N        -1.907  -1.950  -1.814  -1.684  -1.768  -1.636  -1.620  -1.644  -1.426
246   L         0.270   0.266  -0.044   0.203   0.206  -0.219   0.282   0.276  -0.234
247   N         1.004   1.018   1.092   1.178   1.199   1.297   1.065   1.084   1.194
248   N        -1.021  -1.016  -0.889  -1.076  -1.079  -0.960  -1.173  -1.162  -0.984
249   Q         0.270   0.270  -0.046   0.418   0.420  -0.057   0.282   0.282  -0.238
250   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
251   K        -1.087  -1.255  -1.376  -0.952  -1.154  -1.287  -0.949  -1.134  -1.226
252   T        -2.244  -2.243  -2.130  -2.040  -2.045  -1.981  -1.732  -1.718  -1.527
253   E         1.004   1.018   1.092   0.942   0.956   1.083   1.065   1.084   1.194
254   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
255   P         1.004   1.018   1.092   1.203   1.218   1.320   1.065   1.084   1.194
256   Q         1.004   1.018   1.092   1.051   1.071   1.182   1.065   1.084   1.194
257   L         0.270   0.270  -0.046   0.203   0.211  -0.223   0.282   0.282  -0.238
258   V        -0.285  -0.174  -0.120  -0.397  -0.192  -0.156  -0.613  -0.420  -0.369
259   S        -1.021  -1.070  -0.896  -1.189  -1.301  -1.076  -1.173  -1.230  -0.992
260   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
261   R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
262   V         1.004   1.018   1.092   1.053   1.067   1.184   1.065   1.084   1.194
263   P         1.004   1.018   1.092   1.203   1.218   1.320   1.065   1.084   1.194
264   Y         0.270   0.296  -0.042   0.488   0.524   0.048   0.282   0.319  -0.232
265   F        -1.021  -0.877  -0.860  -1.191  -0.984  -0.938  -1.173  -0.977  -0.947
266   D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
267   P         1.004   1.018   1.092   1.203   1.218   1.320   1.065   1.084   1.194
268   S         1.004   1.018   1.092   1.074   1.092   1.203   1.065   1.084   1.194
269   F         1.004   1.018   1.092   1.183   1.202   1.302   1.065   1.084   1.194
270   E         1.004   1.018   1.092   0.942   0.956   1.083   1.065   1.084   1.194
271   A         0.270   0.270  -0.046   0.265   0.264  -0.174   0.282   0.282  -0.238
272   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
273   I         0.270   0.384  -0.037   0.429   0.560  -0.018   0.282   0.440  -0.223
274   K         1.004   1.018   1.092   0.841   0.869   0.992   1.065   1.084   1.194
275   I         1.004   1.018   1.092   1.087   1.114   1.215   1.065   1.084   1.194
276   Q         1.004   1.018   1.092   1.051   1.071   1.182   1.065   1.084   1.194
277   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
278   R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
279   F         1.004   1.018   1.092   1.183   1.202   1.302   1.065   1.084   1.194
280   C         1.004   1.018   1.092   1.294   1.310   1.403   1.065   1.084   1.194
281   T        -0.429  -0.606  -0.810  -0.208  -0.463  -0.836  -0.389  -0.616  -0.882
282   D        -0.092   0.054  -0.076  -0.241  -0.012  -0.255  -0.278  -0.043  -0.291
283   G        -0.429  -0.539  -0.803  -0.150  -0.303  -0.767  -0.389  -0.530  -0.873
284   Y         1.004   1.018   1.092   1.099   1.120   1.226   1.065   1.084   1.194
285   T        -0.894  -0.949  -0.860  -0.930  -1.013  -0.887  -1.061  -1.110  -0.951
286   R         0.270   0.190  -0.052   0.373   0.262  -0.159   0.282   0.165  -0.248
287   L        -0.092  -0.186  -0.134  -0.242  -0.380  -0.280  -0.278  -0.443  -0.393
288   A         1.004   1.018   1.092   0.892   0.908   1.038   1.065   1.084   1.194
289   Q         1.004   1.018   1.092   1.051   1.071   1.182   1.065   1.084   1.194
290   I        -0.894  -0.900  -0.872  -0.953  -0.969  -0.957  -1.061  -1.063  -0.965
291   Q         1.004   1.018   1.092   1.051   1.071   1.182   1.065   1.084   1.194
292   Q         1.004   1.018   1.092   1.051   1.071   1.182   1.065   1.084   1.194
293   Y         0.270   0.270  -0.046   0.505   0.510   0.090   0.282   0.282  -0.238
294   L         0.270   0.190  -0.052   0.218   0.128  -0.191   0.282   0.165  -0.248
295   D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
296   Q        -1.359  -1.449  -1.388  -1.166  -1.288  -1.216  -1.285  -1.372  -1.240
297   Q        -1.569  -1.619  -1.414  -1.655  -1.736  -1.457  -1.508  -1.538  -1.264
298   S        -0.429  -0.606  -0.810  -0.173  -0.411  -0.754  -0.389  -0.616  -0.882
299   R         1.004   1.018   1.092   1.033   1.046   1.166   1.065   1.084   1.194
300   D        -0.285  -0.314  -0.163  -0.612  -0.677  -0.435  -0.613  -0.670  -0.445
301   D        -0.894  -0.957  -0.861  -1.124  -1.198  -1.031  -1.061  -1.115  -0.953
302   Y         1.004   1.018   1.092   1.099   1.120   1.226   1.065   1.084   1.194
303   A         0.270   0.190  -0.052   0.265   0.164  -0.184   0.282   0.165  -0.248
304   N         0.270   0.166  -0.051   0.547   0.417   0.046   0.282   0.129  -0.247
305   G         1.004   1.018   1.092   1.122   1.144   1.247   1.065   1.084   1.194
306   L        -0.750  -0.805  -0.845  -0.886  -0.973  -1.001  -0.837  -0.916  -0.929
307   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
308   D         1.004   1.018   1.092   0.910   0.936   1.054   1.065   1.084   1.194
309   T        -2.034  -1.986  -1.803  -1.994  -1.929  -1.684  -1.732  -1.679  -1.418
310   K        -0.285  -0.284  -0.162  -0.624  -0.623  -0.423  -0.613  -0.616  -0.444
311   I        -0.285  -0.314  -0.163  -0.397  -0.461  -0.241  -0.613  -0.670  -0.445
312   E        -0.285  -0.248  -0.151  -0.601  -0.538  -0.406  -0.613  -0.552  -0.424
313   E        -1.021  -0.986  -0.867  -1.250  -1.189  -1.023  -1.173  -1.130  -0.956
314   L        -0.750  -0.812  -0.848  -0.848  -0.957  -0.928  -0.837  -0.935  -0.933
315   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
316   G        -1.359  -1.180  -1.365  -1.225  -1.010  -1.201  -1.285  -1.098  -1.216
317   Q        -1.087  -1.255  -1.376  -0.796  -1.036  -1.250  -0.949  -1.134  -1.226
318   M         0.270   0.166  -0.051   0.609   0.472   0.108   0.282   0.129  -0.247
319   T        -2.244  -2.044  -2.135  -1.846  -1.591  -1.708  -1.732  -1.548  -1.530
320   S        -2.371  -2.306  -2.143  -2.141  -2.087  -1.830  -1.844  -1.779  -1.536
321   L         1.004   1.018   1.092   0.828   0.851   0.980   1.065   1.084   1.194
322   D        -1.021  -0.889  -0.862  -1.065  -0.839  -0.849  -1.173  -0.994  -0.950
323   I         1.004   1.018   1.092   1.087   1.114   1.215   1.065   1.084   1.194
324   C        -1.442  -1.522  -1.388  -1.228  -1.357  -1.207  -1.397  -1.445  -1.239
325   A        -0.952  -1.008  -0.869  -1.108  -1.143  -0.929  -1.127  -1.162  -0.960
326   L         1.004   1.018   1.092   0.830   0.855   0.981   1.065   1.084   1.194
327   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
328   G         0.270   0.190  -0.052   0.510   0.418   0.050   0.282   0.165  -0.248
329   I        -2.401  -2.301  -2.148  -2.154  -2.006  -1.834  -1.858  -1.767  -1.539
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   K        -0.429  -0.606  -0.810  -0.408  -0.634  -0.941  -0.389  -0.616  -0.882
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25343
Output conservation file - output/P25343
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
