1     M         1.243   1.251   1.319   1.461   1.472   1.566   1.335   1.346   1.447
2     K        -1.433  -1.387  -1.324  -1.367  -1.296  -1.196  -1.273  -1.224  -1.105
3     F        -1.151  -1.133  -0.988  -1.303  -1.282  -1.051  -1.187  -1.160  -0.971
4     F        -0.553  -0.559  -0.485  -0.667  -0.681  -0.590  -0.767  -0.773  -0.670
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    S        -0.749  -0.814  -0.899  -0.626  -0.719  -0.873  -0.724  -0.799  -0.875
15    L        -1.775  -1.697  -1.641  -1.646  -1.521  -1.460  -1.410  -1.336  -1.225
16    A        -1.304  -1.300  -1.305  -1.222  -1.219  -1.257  -1.135  -1.124  -1.086
17    D        -0.749  -0.759  -0.890  -0.641  -0.648  -0.868  -0.724  -0.730  -0.866
18    E        -1.091  -1.105  -0.967  -1.137  -1.164  -0.946  -1.135  -1.135  -0.952
19    A        -1.433  -1.442  -1.328  -1.495  -1.500  -1.334  -1.273  -1.269  -1.108
20    E        -0.407  -0.476  -0.443  -0.499  -0.586  -0.527  -0.586  -0.668  -0.617
21    F        -0.132  -0.225  -0.375   0.010  -0.130  -0.392  -0.175  -0.305  -0.517
22    K        -1.433  -1.407  -1.335  -1.336  -1.313  -1.193  -1.273  -1.237  -1.113
23    S        -1.775  -1.763  -1.641  -1.681  -1.666  -1.490  -1.410  -1.391  -1.225
24    I        -1.433  -1.426  -1.333  -1.304  -1.298  -1.154  -1.273  -1.257  -1.112
25    I        -0.407  -0.456  -0.449  -0.492  -0.576  -0.569  -0.586  -0.656  -0.626
26    I        -1.304  -1.364  -1.319  -1.349  -1.456  -1.386  -1.135  -1.188  -1.098
27    S        -0.407  -0.383  -0.436  -0.405  -0.381  -0.432  -0.586  -0.575  -0.611
28    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    K        -0.962  -0.954  -0.943  -0.853  -0.859  -0.834  -0.998  -0.990  -0.927
31    A        -0.962  -0.970  -0.940  -0.861  -0.895  -0.860  -0.998  -1.006  -0.925
32    V        -0.491  -0.480  -0.453  -0.689  -0.675  -0.613  -0.724  -0.700  -0.634
33    D         0.535   0.517   0.333   0.536   0.518   0.239   0.511   0.483   0.148
34    V        -0.407  -0.456  -0.449  -0.574  -0.655  -0.628  -0.586  -0.656  -0.626
35    I        -0.132  -0.135  -0.356  -0.063  -0.066  -0.415  -0.175  -0.177  -0.491
36    G        -0.407  -0.456  -0.449  -0.588  -0.666  -0.621  -0.586  -0.656  -0.626
37    S        -1.304  -1.364  -1.319  -1.222  -1.317  -1.266  -1.135  -1.188  -1.098
38    K        -0.407  -0.456  -0.449  -0.487  -0.575  -0.559  -0.586  -0.656  -0.626
39    L         0.535   0.517   0.333   0.593   0.568   0.271   0.511   0.483   0.148
40    G         0.535   0.517   0.333   0.483   0.462   0.225   0.511   0.483   0.148
41    G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
42    Q         0.064   0.061   0.166  -0.072  -0.069   0.094  -0.312  -0.320  -0.164
43    V         1.243   1.251   1.319   1.131   1.148   1.253   1.335   1.346   1.447
44    V        -0.132  -0.133  -0.364  -0.044  -0.046  -0.429  -0.175  -0.174  -0.502
45    S        -0.407  -0.379  -0.438  -0.548  -0.536  -0.610  -0.586  -0.569  -0.612
46    F         0.535   0.442   0.328   0.695   0.581   0.425   0.511   0.363   0.140
47    S         1.243   1.251   1.319   1.228   1.248   1.346   1.335   1.346   1.447
48    D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
49    E        -0.407  -0.459  -0.433  -0.430  -0.502  -0.467  -0.586  -0.642  -0.604
50    W         0.535   0.442   0.328   0.776   0.652   0.462   0.511   0.363   0.140
51    F         1.243   1.251   1.319   1.298   1.312   1.411   1.335   1.346   1.447
52    A         1.243   1.251   1.319   1.179   1.191   1.299   1.335   1.346   1.447
53    S        -0.620  -0.617  -0.503  -0.860  -0.851  -0.680  -0.861  -0.854  -0.694
54    A         0.535   0.442   0.328   0.577   0.463   0.321   0.511   0.363   0.140
55    E         0.064   0.070   0.168  -0.221  -0.213  -0.061  -0.312  -0.302  -0.161
56    N         1.243   1.251   1.319   1.332   1.344   1.444   1.335   1.346   1.447
57    L         1.243   1.251   1.319   1.253   1.263   1.369   1.335   1.346   1.447
58    I         0.210   0.199   0.203   0.088   0.065   0.049  -0.037  -0.060  -0.093
59    Q        -0.962  -1.005  -0.944  -0.901  -0.956  -0.841  -0.998  -1.037  -0.929
60    P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
61    T        -0.962  -0.966  -0.930  -0.924  -0.920  -0.859  -0.998  -0.986  -0.912
62    A        -0.132  -0.156  -0.354  -0.092  -0.138  -0.427  -0.175  -0.213  -0.488
63    P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
64    I         0.535   0.517   0.333   0.558   0.536   0.239   0.511   0.483   0.148
65    R         0.535   0.621   0.343   0.645   0.752   0.368   0.511   0.642   0.166
66    D        -0.749  -0.816  -0.902  -0.659  -0.755  -0.880  -0.724  -0.802  -0.879
67    P         0.210   0.219   0.206   0.069   0.080   0.047  -0.037  -0.023  -0.087
68    T        -0.491  -0.427  -0.453  -0.684  -0.615  -0.587  -0.724  -0.650  -0.635
69    R        -0.491  -0.538  -0.456  -0.632  -0.693  -0.572  -0.724  -0.764  -0.639
70    F         0.535   0.528   0.334   0.692   0.688   0.428   0.511   0.501   0.150
71    V         0.210   0.238   0.217   0.017   0.066   0.019  -0.037   0.011  -0.066
72    H        -1.433  -1.417  -1.330  -1.229  -1.219  -1.097  -1.273  -1.250  -1.109
73    S        -0.620  -0.623  -0.506  -0.842  -0.842  -0.658  -0.861  -0.861  -0.698
74    G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
75    A         0.535   0.621   0.343   0.538   0.649   0.261   0.511   0.642   0.166
76    W         1.243   1.251   1.319   1.410   1.423   1.518   1.335   1.346   1.447
77    Y         1.243   1.251   1.319   1.420   1.432   1.527   1.335   1.346   1.447
78    D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
79    G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
80    W         1.243   1.251   1.319   1.410   1.423   1.518   1.335   1.346   1.447
81    E         1.243   1.251   1.319   1.226   1.243   1.344   1.335   1.346   1.447
82    T         1.243   1.251   1.319   1.286   1.299   1.400   1.335   1.346   1.447
83    R         1.243   1.251   1.319   1.278   1.288   1.392   1.335   1.346   1.447
84    R         1.243   1.251   1.319   1.278   1.288   1.392   1.335   1.346   1.447
85    H         1.243   1.251   1.319   1.368   1.380   1.478   1.335   1.346   1.447
86    N         1.243   1.251   1.319   1.332   1.344   1.444   1.335   1.346   1.447
87    E        -0.407  -0.376  -0.424  -0.425  -0.366  -0.452  -0.586  -0.532  -0.592
88    M        -0.491  -0.468  -0.451  -0.637  -0.607  -0.522  -0.724  -0.691  -0.633
89    E         0.210   0.174   0.199   0.114   0.050   0.074  -0.037  -0.106  -0.100
90    Y        -0.962  -1.017  -0.947  -0.868  -0.924  -0.794  -0.998  -1.047  -0.932
91    D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
92    W         0.535   0.621   0.343   0.796   0.902   0.527   0.511   0.642   0.166
93    V         1.243   1.251   1.319   1.131   1.148   1.253   1.335   1.346   1.447
94    I         0.210   0.218   0.209   0.041   0.055  -0.003  -0.037  -0.025  -0.081
95    I        -0.749  -0.757  -0.879  -0.613  -0.640  -0.799  -0.724  -0.733  -0.853
96    K         0.210   0.218   0.209   0.125   0.143   0.098  -0.037  -0.025  -0.081
97    M        -0.962  -0.935  -0.927  -0.867  -0.835  -0.812  -0.998  -0.955  -0.911
98    G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
99    V         0.535   0.442   0.328   0.499   0.379   0.212   0.511   0.363   0.140
100   A        -0.407  -0.434  -0.435  -0.493  -0.531  -0.510  -0.586  -0.620  -0.609
101   A         0.064   0.075   0.169  -0.220  -0.198  -0.055  -0.312  -0.294  -0.158
102   A         0.210   0.163   0.201  -0.009  -0.107  -0.071  -0.037  -0.127  -0.097
103   H        -1.091  -1.071  -0.964  -1.086  -1.050  -0.884  -1.135  -1.103  -0.949
104   I        -0.620  -0.595  -0.494  -0.880  -0.850  -0.687  -0.861  -0.825  -0.682
105   I        -0.749  -0.816  -0.902  -0.678  -0.779  -0.940  -0.724  -0.802  -0.879
106   G         0.535   0.608   0.343   0.446   0.541   0.165   0.511   0.623   0.167
107   G        -0.749  -0.729  -0.882  -0.457  -0.432  -0.745  -0.724  -0.695  -0.857
108   E         1.243   1.251   1.319   1.226   1.243   1.344   1.335   1.346   1.447
109   I         0.210   0.238   0.217   0.041   0.092   0.014  -0.037   0.011  -0.066
110   D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
111   T         1.243   1.251   1.319   1.286   1.299   1.400   1.335   1.346   1.447
112   A         0.535   0.442   0.328   0.544   0.421   0.251   0.511   0.363   0.140
113   F         0.210   0.212   0.204   0.227   0.230   0.204  -0.037  -0.036  -0.091
114   F         1.243   1.251   1.319   1.298   1.312   1.411   1.335   1.346   1.447
115   N         1.243   1.251   1.319   1.332   1.344   1.444   1.335   1.346   1.447
116   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
117   N         1.243   1.251   1.319   1.332   1.344   1.444   1.335   1.346   1.447
118   H         1.243   1.251   1.319   1.368   1.380   1.478   1.335   1.346   1.447
119   A         1.243   1.251   1.319   1.179   1.191   1.299   1.335   1.346   1.447
120   P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
121   F        -1.091  -1.061  -0.965  -1.152  -1.123  -0.957  -1.135  -1.097  -0.950
122   V         0.210   0.175   0.198   0.041  -0.027  -0.028  -0.037  -0.104  -0.103
123   S         0.535   0.517   0.333   0.576   0.561   0.265   0.511   0.483   0.148
124   I         0.535   0.559   0.333   0.485   0.522   0.191   0.511   0.548   0.149
125   E         0.535   0.517   0.333   0.610   0.594   0.339   0.511   0.483   0.148
126   A        -0.407  -0.403  -0.438  -0.539  -0.546  -0.562  -0.586  -0.582  -0.612
127   L        -1.304  -1.305  -1.306  -1.156  -1.167  -1.171  -1.135  -1.133  -1.086
128   Y        -1.091  -1.043  -0.970  -1.023  -0.957  -0.826  -1.135  -1.083  -0.954
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   D        -0.620  -0.597  -0.499  -0.839  -0.798  -0.656  -0.861  -0.827  -0.690
134   E        -2.117  -2.085  -1.919  -1.949  -1.885  -1.662  -1.547  -1.513  -1.316
135   G        -0.749  -0.688  -0.870  -0.665  -0.572  -0.872  -0.724  -0.646  -0.843
136   E        -0.962  -0.955  -0.935  -1.153  -1.165  -1.113  -0.998  -0.992  -0.920
137   E        -0.407  -0.473  -0.449  -0.492  -0.580  -0.553  -0.586  -0.664  -0.626
138   G        -0.504  -0.430  -0.454  -0.704  -0.585  -0.610  -0.720  -0.618  -0.633
139   N        -1.452  -1.427  -1.334  -1.490  -1.457  -1.300  -1.280  -1.248  -1.112
140   I        -1.452  -1.383  -1.332  -1.400  -1.298  -1.230  -1.280  -1.206  -1.109
141   V        -0.903  -0.856  -0.917  -0.926  -0.856  -0.974  -0.907  -0.847  -0.896
142   E        -1.053  -1.040  -0.964  -1.116  -1.085  -0.969  -1.093  -1.073  -0.948
143   D        -0.962  -0.964  -0.932  -0.951  -0.951  -0.897  -0.998  -0.994  -0.917
144   D        -0.749  -0.690  -0.873  -0.737  -0.649  -0.956  -0.724  -0.649  -0.846
145   S        -0.620  -0.615  -0.504  -0.861  -0.854  -0.686  -0.861  -0.851  -0.696
146   R        -0.962  -0.910  -0.928  -0.984  -0.908  -0.939  -0.998  -0.941  -0.912
147   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   W         1.243   1.251   1.319   1.410   1.423   1.518   1.335   1.346   1.447
150   V        -0.962  -0.955  -0.935  -1.033  -1.025  -1.000  -0.998  -0.992  -0.920
151   E        -1.433  -1.430  -1.330  -1.411  -1.402  -1.253  -1.273  -1.261  -1.109
152   I         0.064   0.062   0.166  -0.277  -0.279  -0.106  -0.312  -0.319  -0.164
153   V        -0.407  -0.426  -0.446  -0.513  -0.559  -0.591  -0.586  -0.622  -0.623
154   E        -1.433  -1.393  -1.329  -1.470  -1.413  -1.325  -1.273  -1.229  -1.108
155   K         0.535   0.528   0.334   0.587   0.589   0.267   0.511   0.501   0.150
156   F        -1.775  -1.759  -1.643  -1.613  -1.594  -1.395  -1.410  -1.388  -1.226
157   E         0.535   0.442   0.328   0.594   0.474   0.298   0.511   0.363   0.140
158   C         1.243   1.251   1.319   1.477   1.487   1.581   1.335   1.346   1.447
159   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
160   P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
161   S         0.535   0.442   0.328   0.594   0.477   0.295   0.511   0.363   0.140
162   Q         1.243   1.251   1.319   1.392   1.404   1.501   1.335   1.346   1.447
163   R         0.064   0.106   0.184  -0.137  -0.054   0.055  -0.312  -0.234  -0.130
164   H        -0.132  -0.125  -0.358   0.135   0.144  -0.200  -0.175  -0.164  -0.494
165   L        -0.749  -0.814  -0.899  -0.618  -0.727  -0.899  -0.724  -0.799  -0.875
166   F        -0.132  -0.225  -0.375   0.094  -0.027  -0.233  -0.175  -0.305  -0.517
167   V        -1.304  -1.335  -1.307  -1.291  -1.335  -1.290  -1.135  -1.162  -1.088
168   R        -0.407  -0.473  -0.449  -0.421  -0.519  -0.488  -0.586  -0.664  -0.626
169   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   N        -1.304  -1.311  -1.303  -1.275  -1.284  -1.288  -1.135  -1.138  -1.084
171   G        -1.304  -1.342  -1.315  -1.231  -1.288  -1.273  -1.135  -1.168  -1.094
172   L        -0.620  -0.616  -0.503  -0.783  -0.785  -0.605  -0.861  -0.851  -0.695
173   T         0.535   0.442   0.328   0.653   0.529   0.352   0.511   0.363   0.140
174   K        -1.433  -1.422  -1.327  -1.354  -1.324  -1.176  -1.273  -1.254  -1.107
175   E        -1.304  -1.310  -1.302  -1.144  -1.144  -1.147  -1.135  -1.137  -1.082
176   R        -1.304  -1.300  -1.305  -1.014  -1.010  -1.022  -1.135  -1.124  -1.086
177   F         0.210   0.175   0.198   0.295   0.228   0.225  -0.037  -0.104  -0.103
178   T         0.535   0.517   0.333   0.659   0.638   0.371   0.511   0.483   0.148
179   H         0.535   0.517   0.333   0.755   0.734   0.474   0.511   0.483   0.148
180   I        -0.962  -0.975  -0.945  -1.104  -1.136  -1.061  -0.998  -1.011  -0.930
181   K         0.210   0.214   0.215   0.142   0.146   0.117  -0.037  -0.033  -0.071
182   L         1.243   1.251   1.319   1.253   1.263   1.369   1.335   1.346   1.447
183   K        -1.091  -1.106  -0.970  -1.050  -1.047  -0.839  -1.135  -1.135  -0.955
184   M         1.243   1.251   1.319   1.461   1.472   1.566   1.335   1.346   1.447
185   Y         0.535   0.517   0.333   0.786   0.764   0.478   0.511   0.483   0.148
186   P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
187   D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
188   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
189   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
190   I         1.243   1.251   1.319   1.218   1.232   1.336   1.335   1.346   1.447
191   A         1.243   1.251   1.319   1.179   1.191   1.299   1.335   1.346   1.447
192   R         1.243   1.251   1.319   1.278   1.288   1.392   1.335   1.346   1.447
193   F         1.243   1.251   1.319   1.298   1.312   1.411   1.335   1.346   1.447
194   R         1.243   1.251   1.319   1.278   1.288   1.392   1.335   1.346   1.447
195   L         1.243   1.251   1.319   1.253   1.263   1.369   1.335   1.346   1.447
196   Y         0.535   0.528   0.334   0.786   0.779   0.480   0.511   0.501   0.150
197   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
198   R        -1.775  -1.777  -1.647  -1.534  -1.534  -1.336  -1.410  -1.402  -1.229
199   V         0.535   0.528   0.334   0.478   0.475   0.177   0.511   0.501   0.150
200   V         0.535   0.608   0.343   0.485   0.585   0.208   0.511   0.623   0.167
201   P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
202   P        -0.962  -0.896  -0.927  -1.081  -0.990  -1.017  -0.998  -0.925  -0.911
203   E        -1.304  -1.207  -1.294  -1.144  -1.000  -1.158  -1.135  -1.030  -1.076
204   L        -0.962  -0.903  -0.927  -0.969  -0.886  -0.923  -0.998  -0.932  -0.912
205   K        -1.433  -1.414  -1.327  -1.386  -1.373  -1.239  -1.273  -1.247  -1.107
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   T        -0.962  -0.931  -0.924  -1.017  -0.959  -0.931  -0.998  -0.952  -0.908
215   K        -0.962  -1.011  -0.943  -0.989  -1.049  -0.946  -0.998  -1.038  -0.927
216   D        -0.749  -0.647  -0.868  -0.702  -0.557  -0.895  -0.724  -0.598  -0.841
217   H        -1.775  -1.697  -1.641  -1.720  -1.607  -1.518  -1.410  -1.336  -1.225
218   I        -1.304  -1.319  -1.295  -1.294  -1.323  -1.318  -1.135  -1.146  -1.076
219   I        -0.962  -0.912  -0.924  -0.972  -0.901  -0.899  -0.998  -0.937  -0.907
220   D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
221   L        -0.132   0.007  -0.340   0.002   0.183  -0.304  -0.175   0.017  -0.468
222   A         0.535   0.517   0.333   0.577   0.558   0.327   0.511   0.483   0.148
223   Y        -1.304  -1.364  -1.319  -1.110  -1.192  -1.116  -1.135  -1.188  -1.098
224   V        -0.749  -0.844  -0.902  -0.709  -0.835  -0.920  -0.724  -0.834  -0.879
225   C        -1.433  -1.455  -1.331  -1.217  -1.243  -1.053  -1.273  -1.279  -1.110
226   N         0.535   0.442   0.328   0.692   0.564   0.377   0.511   0.363   0.140
227   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
228   A         0.210   0.214   0.215  -0.055  -0.054  -0.068  -0.037  -0.033  -0.071
229   V        -0.132  -0.202  -0.367  -0.106  -0.203  -0.426  -0.175  -0.273  -0.506
230   A         0.535   0.442   0.328   0.518   0.388   0.195   0.511   0.363   0.140
231   L        -0.407  -0.418  -0.443  -0.542  -0.578  -0.610  -0.586  -0.609  -0.619
232   K        -1.433  -1.415  -1.327  -1.420  -1.372  -1.254  -1.273  -1.248  -1.107
233   Y        -1.433  -1.389  -1.331  -1.204  -1.135  -1.061  -1.273  -1.224  -1.110
234   S         1.243   1.251   1.319   1.228   1.248   1.346   1.335   1.346   1.447
235   D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
236   Q         1.243   1.251   1.319   1.392   1.404   1.501   1.335   1.346   1.447
237   H         1.243   1.251   1.319   1.368   1.380   1.478   1.335   1.346   1.447
238   F         1.243   1.251   1.319   1.298   1.312   1.411   1.335   1.346   1.447
239   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
240   S        -0.491  -0.536  -0.457  -0.612  -0.661  -0.538  -0.724  -0.762  -0.640
241   V        -0.407  -0.426  -0.446  -0.553  -0.592  -0.625  -0.586  -0.622  -0.623
242   D         0.535   0.517   0.333   0.554   0.537   0.277   0.511   0.483   0.148
243   N         1.243   1.251   1.319   1.332   1.344   1.444   1.335   1.346   1.447
244   L         1.243   1.251   1.319   1.253   1.263   1.369   1.335   1.346   1.447
245   L         0.210   0.199   0.203   0.108   0.082   0.059  -0.037  -0.060  -0.093
246   L         0.535   0.517   0.333   0.648   0.626   0.387   0.511   0.483   0.148
247   P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
248   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
249   R         0.535   0.556   0.335   0.636   0.664   0.337   0.511   0.543   0.152
250   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
251   H        -0.749  -0.816  -0.902  -0.542  -0.656  -0.837  -0.724  -0.802  -0.879
252   D         0.210   0.174   0.199   0.083   0.024   0.055  -0.037  -0.106  -0.100
253   M         1.243   1.251   1.319   1.461   1.472   1.566   1.335   1.346   1.447
254   S         0.064   0.083   0.172  -0.297  -0.262  -0.114  -0.312  -0.277  -0.152
255   D         0.535   0.556   0.335   0.537   0.570   0.243   0.511   0.543   0.152
256   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
257   W         1.243   1.251   1.319   1.410   1.423   1.518   1.335   1.346   1.447
258   E         1.243   1.251   1.319   1.226   1.243   1.344   1.335   1.346   1.447
259   T         1.243   1.251   1.319   1.286   1.299   1.400   1.335   1.346   1.447
260   K        -0.407  -0.456  -0.449  -0.499  -0.585  -0.578  -0.586  -0.656  -0.626
261   R         1.243   1.251   1.319   1.278   1.288   1.392   1.335   1.346   1.447
262   S         1.243   1.251   1.319   1.228   1.248   1.346   1.335   1.346   1.447
263   R         1.243   1.251   1.319   1.278   1.288   1.392   1.335   1.346   1.447
264   Q        -0.407  -0.400  -0.441  -0.431  -0.425  -0.462  -0.586  -0.580  -0.617
265   P         0.210   0.163   0.201   0.163   0.072   0.108  -0.037  -0.127  -0.097
266   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
267   H         1.243   1.251   1.319   1.368   1.380   1.478   1.335   1.346   1.447
268   T         0.210   0.261   0.222   0.017   0.104   0.027  -0.037   0.053  -0.057
269   D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
270   W         1.243   1.251   1.319   1.410   1.423   1.518   1.335   1.346   1.447
271   A        -0.407  -0.413  -0.439  -0.593  -0.598  -0.626  -0.586  -0.590  -0.611
272   V         0.064   0.094   0.176  -0.258  -0.195  -0.078  -0.312  -0.256  -0.145
273   I         0.535   0.442   0.328   0.558   0.428   0.231   0.511   0.363   0.140
274   Q        -0.407  -0.476  -0.443  -0.370  -0.469  -0.422  -0.586  -0.668  -0.617
275   L         1.243   1.251   1.319   1.253   1.263   1.369   1.335   1.346   1.447
276   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
277   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   E        -0.132  -0.133  -0.364  -0.123  -0.126  -0.502  -0.175  -0.174  -0.502
279   S        -0.962  -1.003  -0.934  -0.933  -0.986  -0.884  -0.998  -1.027  -0.918
280   S        -1.304  -1.207  -1.294  -1.342  -1.198  -1.324  -1.135  -1.030  -1.076
281   F        -1.433  -1.407  -1.335  -1.229  -1.168  -1.073  -1.273  -1.237  -1.113
282   I         0.535   0.608   0.343   0.578   0.674   0.299   0.511   0.623   0.167
283   E        -1.433  -1.448  -1.331  -1.347  -1.362  -1.186  -1.273  -1.273  -1.110
284   K        -1.775  -1.753  -1.642  -1.661  -1.630  -1.471  -1.410  -1.384  -1.225
285   I        -0.962  -1.007  -0.936  -1.081  -1.145  -1.033  -0.998  -1.033  -0.920
286   I        -0.962  -0.957  -0.931  -1.026  -1.017  -0.937  -0.998  -0.988  -0.915
287   V        -0.132  -0.202  -0.367  -0.142  -0.241  -0.493  -0.175  -0.273  -0.506
288   D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
289   T         1.243   1.251   1.319   1.286   1.299   1.400   1.335   1.346   1.447
290   A        -0.132  -0.144  -0.354  -0.071  -0.093  -0.389  -0.175  -0.198  -0.489
291   H         0.535   0.556   0.335   0.753   0.780   0.474   0.511   0.543   0.152
292   F         1.243   1.251   1.319   1.298   1.312   1.411   1.335   1.346   1.447
293   R         0.210   0.174   0.199   0.142   0.075   0.087  -0.037  -0.106  -0.100
294   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
295   N         1.243   1.251   1.319   1.332   1.344   1.444   1.335   1.346   1.447
296   F         0.210   0.163   0.201   0.227   0.149   0.199  -0.037  -0.127  -0.097
297   P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
298   Q         0.535   0.442   0.328   0.750   0.624   0.428   0.511   0.363   0.140
299   F        -0.962  -1.017  -0.947  -0.923  -0.996  -0.879  -0.998  -1.047  -0.932
300   I        -0.491  -0.470  -0.453  -0.678  -0.649  -0.561  -0.724  -0.693  -0.634
301   T        -0.962  -0.983  -0.934  -0.915  -0.940  -0.875  -0.998  -1.003  -0.916
302   V         0.210   0.163   0.201   0.005  -0.078  -0.026  -0.037  -0.127  -0.097
303   E        -1.433  -1.421  -1.330  -1.342  -1.310  -1.164  -1.273  -1.249  -1.109
304   G         0.064   0.083   0.172  -0.312  -0.277  -0.137  -0.312  -0.277  -0.152
305   C        -0.132  -0.098  -0.358  -0.026   0.021  -0.351  -0.175  -0.126  -0.493
306   L        -1.433  -1.452  -1.331  -1.382  -1.413  -1.237  -1.273  -1.277  -1.110
307   K        -1.452  -1.477  -1.348  -1.438  -1.455  -1.254  -1.280  -1.293  -1.123
308   E        -1.452  -1.389  -1.335  -1.516  -1.399  -1.354  -1.280  -1.212  -1.112
309   S        -1.304  -1.209  -1.289  -1.214  -1.075  -1.209  -1.135  -1.032  -1.071
310   E        -0.749  -0.747  -0.880  -0.685  -0.682  -0.920  -0.724  -0.722  -0.854
311   S        -1.304  -1.305  -1.306  -1.278  -1.288  -1.322  -1.135  -1.133  -1.086
312   S        -1.433  -1.436  -1.327  -1.420  -1.410  -1.250  -1.273  -1.265  -1.107
313   E        -0.407  -0.400  -0.441  -0.470  -0.467  -0.521  -0.586  -0.580  -0.617
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   N        -2.117  -2.085  -1.919  -2.005  -1.962  -1.716  -1.547  -1.513  -1.316
316   T        -1.304  -1.310  -1.302  -1.231  -1.262  -1.227  -1.135  -1.137  -1.082
317   G        -0.749  -0.754  -0.879  -0.692  -0.706  -0.897  -0.724  -0.731  -0.853
318   E        -0.491  -0.463  -0.447  -0.693  -0.646  -0.600  -0.724  -0.683  -0.627
319   G        -1.304  -1.364  -1.319  -1.331  -1.433  -1.390  -1.135  -1.188  -1.098
320   T        -2.117  -2.085  -1.919  -1.923  -1.861  -1.638  -1.547  -1.513  -1.316
321   W         1.243   1.251   1.319   1.410   1.423   1.518   1.335   1.346   1.447
322   V        -1.304  -1.227  -1.288  -1.321  -1.200  -1.302  -1.135  -1.051  -1.070
323   E        -1.304  -1.279  -1.293  -1.157  -1.117  -1.143  -1.135  -1.108  -1.075
324   L        -0.491  -0.538  -0.456  -0.714  -0.772  -0.635  -0.724  -0.764  -0.639
325   V         0.210   0.174   0.199   0.005  -0.058  -0.029  -0.037  -0.106  -0.100
326   G        -1.433  -1.452  -1.331  -1.575  -1.592  -1.397  -1.273  -1.277  -1.110
327   K        -1.091  -1.106  -0.970  -1.217  -1.230  -1.024  -1.135  -1.135  -0.955
328   S        -0.749  -0.816  -0.902  -0.672  -0.770  -0.939  -0.724  -0.802  -0.879
329   K         0.535   0.556   0.335   0.630   0.667   0.360   0.511   0.543   0.152
330   T        -0.749  -0.816  -0.902  -0.566  -0.671  -0.812  -0.724  -0.802  -0.879
331   G        -0.132  -0.053  -0.344  -0.187  -0.079  -0.508  -0.175  -0.065  -0.474
332   P         0.535   0.608   0.343   0.647   0.739   0.349   0.511   0.623   0.167
333   D         0.210   0.174   0.199   0.097   0.040   0.075  -0.037  -0.106  -0.100
334   K        -0.749  -0.816  -0.902  -0.566  -0.646  -0.782  -0.724  -0.802  -0.879
335   E         1.243   1.251   1.319   1.226   1.243   1.344   1.335   1.346   1.447
336   H        -0.132  -0.041  -0.345   0.099   0.222  -0.243  -0.175  -0.049  -0.475
337   V        -0.962  -0.937  -0.932  -1.073  -1.049  -1.023  -0.998  -0.973  -0.917
338   Y        -0.491  -0.488  -0.455  -0.493  -0.485  -0.441  -0.724  -0.712  -0.637
339   E        -1.433  -1.453  -1.332  -1.434  -1.457  -1.278  -1.273  -1.277  -1.111
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   I        -0.620  -0.629  -0.505  -0.903  -0.914  -0.712  -0.861  -0.870  -0.698
342   R        -2.117  -2.085  -1.919  -1.935  -1.867  -1.649  -1.547  -1.513  -1.316
343   K        -0.962  -0.880  -0.927  -0.997  -0.875  -0.958  -0.998  -0.917  -0.912
344   S        -1.091  -1.070  -0.966  -1.188  -1.145  -0.985  -1.135  -1.106  -0.951
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   I        -1.304  -1.348  -1.311  -1.147  -1.214  -1.164  -1.135  -1.174  -1.091
347   R        -0.962  -0.975  -0.945  -1.051  -1.069  -0.996  -0.998  -1.011  -0.930
348   V        -1.433  -1.452  -1.335  -1.240  -1.261  -1.107  -1.273  -1.276  -1.113
349   S         0.064   0.059   0.166  -0.153  -0.159   0.009  -0.312  -0.324  -0.165
350   H         1.243   1.251   1.319   1.368   1.380   1.478   1.335   1.346   1.447
351   V         0.210   0.238   0.217  -0.009   0.041  -0.016  -0.037   0.011  -0.066
352   K        -0.132  -0.144  -0.354  -0.014  -0.031  -0.351  -0.175  -0.198  -0.489
353   L        -0.132  -0.144  -0.354   0.037   0.019  -0.264  -0.175  -0.198  -0.489
354   T         0.210   0.163   0.201   0.139   0.048   0.082  -0.037  -0.127  -0.097
355   I         0.535   0.621   0.343   0.614   0.718   0.371   0.511   0.642   0.166
356   I         0.535   0.528   0.334   0.558   0.552   0.241   0.511   0.501   0.150
357   P         1.243   1.251   1.319   1.300   1.307   1.413   1.335   1.346   1.447
358   D         1.243   1.251   1.319   1.181   1.196   1.301   1.335   1.346   1.447
359   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
360   G         1.243   1.251   1.319   1.099   1.110   1.223   1.335   1.346   1.447
361   V         1.243   1.251   1.319   1.131   1.148   1.253   1.335   1.346   1.447
362   K         0.535   0.556   0.335   0.603   0.642   0.303   0.511   0.543   0.152
363   R         1.243   1.251   1.319   1.278   1.288   1.392   1.335   1.346   1.447
364   I        -0.620  -0.619  -0.502  -0.880  -0.877  -0.698  -0.861  -0.856  -0.693
365   R         1.243   1.251   1.319   1.278   1.288   1.392   1.335   1.346   1.447
366   V        -0.132  -0.156  -0.354  -0.157  -0.192  -0.500  -0.175  -0.213  -0.488
367   W        -0.132  -0.199  -0.367   0.094   0.006  -0.221  -0.175  -0.270  -0.506
368   G         0.210   0.199   0.203  -0.055  -0.080  -0.090  -0.037  -0.060  -0.093
369   -        -0.553  -0.565  -0.487  -0.596  -0.624  -0.518  -0.767  -0.782  -0.673
370   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
371   -        -0.579  -0.599  -0.488  -0.835  -0.863  -0.685  -0.817  -0.833  -0.676
372   -        -0.398  -0.302  -0.430  -0.504  -0.353  -0.568  -0.548  -0.410  -0.594
373   Y        -1.433  -1.413  -1.327  -1.386  -1.357  -1.219  -1.273  -1.245  -1.107
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25335
Output conservation file - output/P25335
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
