1     M         1.463   1.487   1.563   1.691   1.724   1.842   1.628   1.660   1.787
2     S        -1.355  -1.359  -1.312  -1.261  -1.275  -1.228  -1.114  -1.100  -1.016
3     S        -1.515  -1.450  -1.339  -1.431  -1.343  -1.185  -1.248  -1.185  -1.035
4     V        -1.809  -1.791  -1.614  -1.630  -1.651  -1.396  -1.350  -1.327  -1.132
5     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    H        -1.197  -1.207  -1.068  -0.951  -0.953  -0.789  -1.109  -1.106  -0.939
22    L        -1.537  -1.434  -1.354  -1.498  -1.305  -1.275  -1.253  -1.149  -1.044
23    T         0.096   0.165  -0.136   0.223   0.313  -0.135   0.043   0.141  -0.339
24    E        -0.729  -0.701  -0.674  -0.806  -0.808  -0.765  -0.821  -0.794  -0.738
25    G         0.759   0.791   0.544   0.650   0.696   0.310   0.764   0.810   0.317
26    G         1.463   1.487   1.563   1.319   1.354   1.490   1.628   1.660   1.787
27    N         0.436   0.486   0.474   0.494   0.575   0.506   0.187   0.270   0.177
28    M        -0.857  -0.886  -0.703  -0.977  -1.003  -0.729  -0.965  -0.978  -0.768
29    A         1.463   1.487   1.563   1.372   1.397   1.540   1.628   1.660   1.787
30    F         0.759   0.599   0.520   0.902   0.672   0.526   0.764   0.480   0.269
31    H         0.436   0.486   0.474   0.559   0.643   0.563   0.187   0.270   0.177
32    N         0.436   0.486   0.474   0.489   0.574   0.501   0.187   0.270   0.177
33    H        -0.177  -0.176  -0.195  -0.087  -0.122  -0.138  -0.389  -0.410  -0.433
34    L        -0.759  -0.733  -0.935  -0.725  -0.667  -0.979  -0.647  -0.604  -0.809
35    N         0.159   0.233  -0.041   0.327   0.443  -0.003   0.111   0.222  -0.199
36    D        -0.748  -0.743  -0.668  -0.688  -0.677  -0.611  -0.822  -0.815  -0.729
37    F         0.433   0.509   0.015   0.634   0.726   0.045   0.520   0.622  -0.111
38    A        -0.759  -0.870  -1.004  -0.679  -0.866  -1.039  -0.647  -0.776  -0.881
39    H        -0.759  -0.770  -0.984  -0.350  -0.388  -0.755  -0.647  -0.674  -0.861
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    I        -0.644  -0.715  -0.971  -0.488  -0.571  -0.951  -0.490  -0.567  -0.844
43    E        -0.168  -0.262  -0.201  -0.110  -0.277  -0.220  -0.349  -0.493  -0.440
44    D         0.159   0.067  -0.076   0.404   0.295   0.050   0.111  -0.010  -0.252
45    P        -0.057  -0.046  -0.509   0.360   0.377  -0.304   0.053   0.070  -0.534
46    L        -0.922  -0.950  -0.978  -0.909  -0.914  -0.909  -0.881  -0.888  -0.859
47    E         0.433   0.352  -0.007   0.745   0.651   0.149   0.520   0.404  -0.145
48    R        -0.311  -0.365  -0.606   0.011  -0.074  -0.431  -0.297  -0.374  -0.659
49    R        -0.057  -0.159  -0.511   0.366   0.241  -0.268   0.053  -0.077  -0.537
50    R        -0.311  -0.365  -0.606  -0.006  -0.089  -0.480  -0.297  -0.374  -0.659
51    L         0.457   0.475   0.514   0.228   0.250   0.299   0.228   0.249   0.256
52    A        -0.013  -0.051  -0.150  -0.083  -0.140  -0.254  -0.181  -0.241  -0.370
53    L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
54    E        -0.311  -0.309  -0.563  -0.076  -0.116  -0.479  -0.297  -0.320  -0.613
55    S        -1.192  -1.150  -1.053  -1.028  -0.964  -0.837  -1.114  -1.068  -0.928
56    I        -0.110  -0.189  -0.165  -0.328  -0.410  -0.328  -0.356  -0.445  -0.398
57    D        -0.013  -0.051  -0.150   0.083   0.021  -0.161  -0.181  -0.241  -0.370
58    D        -1.706  -1.671  -1.577  -1.455  -1.422  -1.266  -1.289  -1.250  -1.109
59    E        -0.965  -0.928  -1.012  -0.982  -0.952  -1.048  -0.881  -0.848  -0.892
60    G        -1.490  -1.507  -1.352  -1.507  -1.493  -1.273  -1.231  -1.224  -1.044
61    F        -0.013  -0.051  -0.150   0.029  -0.028  -0.160  -0.181  -0.241  -0.370
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    G         0.338   0.332   0.440  -0.032  -0.048   0.130  -0.006  -0.032   0.107
74    W        -0.013  -0.029  -0.152   0.178   0.128  -0.087  -0.181  -0.225  -0.374
75    Q        -1.788  -1.709  -1.606  -1.437  -1.338  -1.174  -1.347  -1.282  -1.128
76    Q        -0.408  -0.380  -0.237  -0.392  -0.350  -0.142  -0.706  -0.665  -0.489
77    V        -0.759  -0.783  -0.671  -1.001  -1.009  -0.866  -0.881  -0.879  -0.736
78    K         0.280   0.308   0.427   0.176   0.217   0.398  -0.122  -0.082   0.080
79    T        -0.841  -0.761  -0.689  -1.095  -0.991  -0.849  -0.939  -0.846  -0.753
80    I        -0.461  -0.610  -0.638  -0.504  -0.696  -0.753  -0.531  -0.682  -0.697
81    S        -1.355  -1.324  -1.302  -1.266  -1.273  -1.277  -1.114  -1.087  -1.007
82    I        -0.667  -0.664  -0.631  -0.912  -0.897  -0.847  -0.764  -0.751  -0.691
83    A         1.463   1.487   1.563   1.403   1.435   1.569   1.628   1.660   1.787
84    G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
85    V        -0.057  -0.119  -0.506   0.176   0.097  -0.529   0.053  -0.029  -0.531
86    G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
87    F         1.463   1.487   1.563   1.513   1.545   1.673   1.628   1.660   1.787
88    L        -0.408  -0.380  -0.234  -0.617  -0.590  -0.391  -0.706  -0.665  -0.485
89    T         0.338   0.332   0.440   0.083   0.046   0.203  -0.006  -0.032   0.107
90    D         1.463   1.487   1.563   1.626   1.665   1.780   1.628   1.660   1.787
91    S         0.940   1.009   0.657   1.086   1.171   0.674   1.045   1.141   0.535
92    Y         1.463   1.487   1.563   1.661   1.696   1.813   1.628   1.660   1.787
93    D         1.463   1.487   1.563   1.626   1.665   1.780   1.628   1.660   1.787
94    I         0.338   0.332   0.440  -0.061  -0.087   0.079  -0.006  -0.032   0.107
95    F         1.463   1.487   1.563   1.513   1.545   1.673   1.628   1.660   1.787
96    A        -0.110  -0.188  -0.174  -0.409  -0.515  -0.463  -0.356  -0.443  -0.408
97    I         0.940   0.851   0.638   0.937   0.840   0.530   1.045   0.906   0.500
98    N         0.940   0.851   0.638   1.185   1.082   0.760   1.045   0.906   0.500
99    L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
100   G        -0.759  -0.758  -0.677  -1.031  -0.991  -0.916  -0.881  -0.847  -0.743
101   I        -1.057  -1.035  -1.024  -1.135  -1.106  -1.021  -0.997  -0.980  -0.904
102   T        -0.922  -0.906  -1.010  -0.788  -0.763  -0.906  -0.881  -0.851  -0.890
103   M         0.280   0.299   0.427   0.074   0.091   0.276  -0.122  -0.100   0.079
104   M        -0.706  -0.685  -0.628  -0.773  -0.757  -0.643  -0.822  -0.782  -0.688
105   S        -1.057  -1.104  -1.035  -1.082  -1.171  -1.071  -0.997  -1.027  -0.912
106   Y         0.940   0.851   0.638   1.207   1.100   0.747   1.045   0.906   0.500
107   V         0.338   0.332   0.440   0.070   0.035   0.192  -0.006  -0.032   0.107
108   Y         0.940   1.022   0.656   1.220   1.321   0.818   1.045   1.159   0.533
109   W         0.940   0.851   0.638   1.286   1.181   0.847   1.045   0.906   0.500
110   -         1.463   1.487   1.563   1.303   1.339   1.475   1.628   1.660   1.787
111   -         0.370   0.347   0.457   0.093   0.055   0.238   0.059  -0.001   0.141
112   -        -0.819  -0.834  -0.691  -1.236  -1.258  -1.039  -0.921  -0.923  -0.755
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -0.857  -0.875  -0.679  -1.030  -1.038  -0.760  -0.965  -0.968  -0.745
118   -         0.096   0.161  -0.065   0.050   0.144  -0.157   0.043   0.135  -0.232
119   H        -1.922  -1.851  -1.811  -1.386  -1.298  -1.230  -1.347  -1.288  -1.182
120   G         0.433   0.317  -0.016   0.467   0.339  -0.085   0.520   0.357  -0.158
121   S        -1.571  -1.529  -1.561  -1.093  -1.043  -1.136  -1.172  -1.135  -1.097
122   M        -0.706  -0.629  -0.665  -0.618  -0.505  -0.565  -0.822  -0.737  -0.730
123   P         1.463   1.487   1.563   1.660   1.691   1.812   1.628   1.660   1.787
124   G        -1.057  -0.970  -1.031  -1.010  -0.893  -0.985  -0.997  -0.910  -0.910
125   P        -0.532  -0.557  -0.638  -0.672  -0.726  -0.754  -0.647  -0.667  -0.701
126   S        -0.316  -0.325  -0.230  -0.576  -0.602  -0.452  -0.589  -0.598  -0.480
127   Q        -1.706  -1.663  -1.603  -1.339  -1.256  -1.199  -1.289  -1.236  -1.125
128   T         0.338   0.332   0.440   0.055   0.017   0.171  -0.006  -0.032   0.107
129   L         0.433   0.241  -0.033   0.474   0.226  -0.204   0.520   0.252  -0.185
130   L        -0.408  -0.381  -0.238  -0.831  -0.774  -0.573  -0.706  -0.666  -0.490
131   K         0.338   0.332   0.440   0.276   0.253   0.410  -0.006  -0.032   0.107
132   V        -0.110  -0.188  -0.174  -0.315  -0.440  -0.422  -0.356  -0.443  -0.408
133   S         0.338   0.313   0.429   0.104   0.023   0.197  -0.006  -0.070   0.084
134   T         0.159   0.178  -0.074   0.251   0.273  -0.131   0.111   0.132  -0.249
135   S         0.338   0.332   0.440   0.216   0.197   0.359  -0.006  -0.032   0.107
136   V        -0.110  -0.188  -0.174  -0.325  -0.444  -0.425  -0.356  -0.443  -0.408
137   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
138   T         0.338   0.332   0.440   0.213   0.194   0.357  -0.006  -0.032   0.107
139   V         0.457   0.438   0.485   0.325   0.278   0.306   0.228   0.178   0.199
140   I        -0.013  -0.090  -0.144  -0.147  -0.230  -0.286  -0.181  -0.271  -0.357
141   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
142   Q         1.463   1.487   1.563   1.683   1.719   1.834   1.628   1.660   1.787
143   F        -0.543  -0.565  -0.612  -0.700  -0.719  -0.840  -0.589  -0.596  -0.669
144   G        -0.461  -0.450  -0.616  -0.671  -0.686  -0.830  -0.531  -0.534  -0.675
145   F         1.463   1.487   1.563   1.513   1.545   1.673   1.628   1.660   1.787
146   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
147   T        -1.057  -1.026  -1.033  -1.179  -1.103  -1.141  -0.997  -0.941  -0.909
148   L        -0.532  -0.567  -0.595  -0.575  -0.625  -0.689  -0.647  -0.670  -0.658
149   A         0.338   0.332   0.440  -0.066  -0.101   0.065  -0.006  -0.032   0.107
150   D         1.463   1.487   1.563   1.626   1.665   1.780   1.628   1.660   1.787
151   I        -0.759  -0.699  -0.672  -0.964  -0.857  -0.797  -0.881  -0.807  -0.738
152   V         0.280   0.299   0.432   0.023   0.047   0.260  -0.122  -0.100   0.089
153   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
154   R         1.463   1.487   1.563   1.644   1.676   1.797   1.628   1.660   1.787
155   K         1.463   1.487   1.563   1.604   1.637   1.760   1.628   1.660   1.787
156   R        -0.706  -0.711  -0.670  -0.710  -0.707  -0.631  -0.822  -0.802  -0.735
157   I        -0.110  -0.188  -0.174  -0.323  -0.402  -0.331  -0.356  -0.443  -0.408
158   Y         1.463   1.487   1.563   1.661   1.696   1.813   1.628   1.660   1.787
159   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
160   M        -0.922  -0.808  -1.001  -0.909  -0.768  -0.958  -0.881  -0.773  -0.882
161   E         1.463   1.487   1.563   1.599   1.632   1.755   1.628   1.660   1.787
162   L         0.338   0.332   0.440   0.102   0.090   0.272  -0.006  -0.032   0.107
163   I        -0.311  -0.416  -0.575  -0.272  -0.419  -0.654  -0.297  -0.430  -0.628
164   I        -0.706  -0.715  -0.618  -0.973  -0.951  -0.812  -0.822  -0.810  -0.681
165   M        -0.110  -0.188  -0.174  -0.098  -0.220  -0.221  -0.356  -0.443  -0.408
166   I         1.463   1.487   1.563   1.377   1.417   1.545   1.628   1.660   1.787
167   V        -1.139  -1.046  -1.046  -1.438  -1.270  -1.296  -1.056  -0.957  -0.921
168   C         0.433   0.557   0.005   0.552   0.697   0.004   0.520   0.687  -0.126
169   T         1.463   1.487   1.563   1.533   1.567   1.692   1.628   1.660   1.787
170   I        -0.095  -0.134  -0.147  -0.278  -0.348  -0.420  -0.239  -0.300  -0.358
171   L        -0.543  -0.482  -0.611  -0.689  -0.615  -0.813  -0.589  -0.519  -0.665
172   Q        -0.311  -0.388  -0.601  -0.040  -0.152  -0.588  -0.297  -0.388  -0.651
173   T        -0.706  -0.707  -0.667  -0.770  -0.777  -0.725  -0.822  -0.799  -0.731
174   T        -1.192  -1.208  -1.050  -1.192  -1.214  -0.956  -1.114  -1.107  -0.925
175   V        -1.355  -1.251  -1.296  -1.404  -1.275  -1.338  -1.114  -1.021  -0.999
176   A        -0.532  -0.557  -0.638  -0.668  -0.671  -0.775  -0.647  -0.667  -0.701
177   H        -1.624  -1.635  -1.599  -1.242  -1.280  -1.243  -1.231  -1.223  -1.123
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   S         0.159   0.140  -0.088   0.270   0.216  -0.146   0.111   0.053  -0.274
182   P         0.433   0.549   0.007   0.809   0.944   0.234   0.520   0.676  -0.123
183   A        -1.057  -1.130  -1.036  -1.348  -1.426  -1.291  -0.997  -1.038  -0.912
184   I        -0.759  -0.802  -0.981  -0.767  -0.831  -1.164  -0.647  -0.686  -0.856
185   N        -0.110  -0.067  -0.159  -0.087  -0.049  -0.137  -0.356  -0.320  -0.387
186   F        -0.110  -0.188  -0.174  -0.152  -0.250  -0.239  -0.356  -0.443  -0.408
187   V        -0.532  -0.550  -0.637  -0.466  -0.487  -0.583  -0.647  -0.661  -0.700
188   A        -0.110  -0.188  -0.174  -0.233  -0.325  -0.315  -0.356  -0.443  -0.408
189   V        -0.110  -0.185  -0.139  -0.330  -0.440  -0.383  -0.356  -0.436  -0.366
190   L        -0.110  -0.132  -0.141  -0.341  -0.329  -0.370  -0.356  -0.345  -0.359
191   T        -1.139  -1.187  -1.049  -1.133  -1.226  -1.050  -1.056  -1.085  -0.923
192   F         0.096   0.165  -0.136   0.220   0.314  -0.197   0.043   0.141  -0.339
193   Y        -0.759  -0.717  -0.942  -0.380  -0.310  -0.742  -0.647  -0.587  -0.816
194   R         1.463   1.487   1.563   1.644   1.676   1.797   1.628   1.660   1.787
195   I        -0.245  -0.319  -0.222  -0.393  -0.505  -0.364  -0.472  -0.577  -0.468
196   V        -0.532  -0.527  -0.599  -0.697  -0.663  -0.732  -0.647  -0.618  -0.657
197   M         0.338   0.332   0.440   0.226   0.185   0.329  -0.006  -0.032   0.107
198   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
199   I        -0.013  -0.050  -0.134  -0.190  -0.248  -0.385  -0.181  -0.239  -0.353
200   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
201   I         1.463   1.487   1.563   1.377   1.417   1.545   1.628   1.660   1.787
202   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
203   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
204   D         1.463   1.487   1.563   1.626   1.665   1.780   1.628   1.660   1.787
205   Y         1.463   1.487   1.563   1.661   1.696   1.813   1.628   1.660   1.787
206   P         1.463   1.487   1.563   1.660   1.691   1.812   1.628   1.660   1.787
207   L         0.338   0.332   0.440   0.102   0.090   0.272  -0.006  -0.032   0.107
208   S         1.463   1.487   1.563   1.537   1.570   1.696   1.628   1.660   1.787
209   S         0.338   0.332   0.440   0.104   0.070   0.228  -0.006  -0.032   0.107
210   I        -0.311  -0.400  -0.595  -0.331  -0.437  -0.761  -0.297  -0.395  -0.643
211   I         1.463   1.487   1.563   1.377   1.417   1.545   1.628   1.660   1.787
212   T         0.649   0.720   0.575   0.711   0.814   0.568   0.578   0.692   0.379
213   S         1.463   1.487   1.563   1.537   1.570   1.696   1.628   1.660   1.787
214   E         1.463   1.487   1.563   1.599   1.632   1.755   1.628   1.660   1.787
215   F        -0.013  -0.090  -0.144   0.033  -0.055  -0.118  -0.181  -0.271  -0.357
216   A         0.280   0.298   0.427  -0.053  -0.027   0.188  -0.122  -0.101   0.079
217   T        -0.095  -0.138  -0.170  -0.101  -0.192  -0.303  -0.239  -0.309  -0.393
218   T        -0.095  -0.141  -0.184  -0.164  -0.256  -0.425  -0.239  -0.311  -0.412
219   K        -0.311  -0.334  -0.557  -0.029  -0.078  -0.393  -0.297  -0.340  -0.601
220   W         0.338   0.332   0.440   0.393   0.367   0.514  -0.006  -0.032   0.107
221   R         1.463   1.487   1.563   1.644   1.676   1.797   1.628   1.660   1.787
222   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
223   A         0.457   0.475   0.514   0.269   0.292   0.337   0.228   0.249   0.256
224   I        -0.408  -0.380  -0.237  -0.763  -0.712  -0.472  -0.706  -0.665  -0.489
225   M        -0.095  -0.138  -0.170  -0.009  -0.103  -0.268  -0.239  -0.309  -0.393
226   G        -0.369  -0.360  -0.215  -0.800  -0.791  -0.567  -0.647  -0.635  -0.460
227   A        -0.311  -0.400  -0.595  -0.310  -0.415  -0.740  -0.297  -0.395  -0.643
228   V         0.457   0.438   0.485   0.325   0.278   0.306   0.228   0.178   0.199
229   F         1.463   1.487   1.563   1.513   1.545   1.673   1.628   1.660   1.787
230   A         0.338   0.342   0.435   0.052   0.050   0.196  -0.006  -0.011   0.097
231   N        -0.013  -0.088  -0.118   0.084  -0.005  -0.048  -0.181  -0.268  -0.319
232   Q         1.463   1.487   1.563   1.683   1.719   1.834   1.628   1.660   1.787
233   A         0.649   0.743   0.575   0.458   0.600   0.315   0.578   0.730   0.378
234   W        -0.369  -0.358  -0.205  -0.484  -0.485  -0.269  -0.647  -0.633  -0.443
235   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
236   Q         0.338   0.332   0.440   0.301   0.273   0.418  -0.006  -0.032   0.107
237   I        -0.013   0.092  -0.095  -0.240  -0.062  -0.343  -0.181  -0.017  -0.286
238   S        -0.759  -0.592  -0.920  -0.657  -0.426  -0.908  -0.647  -0.447  -0.793
239   G         0.457   0.460   0.479   0.130   0.126   0.127   0.228   0.220   0.187
240   G        -0.532  -0.529  -0.595  -0.772  -0.723  -0.742  -0.647  -0.622  -0.651
241   I        -0.057  -0.185  -0.528   0.042  -0.122  -0.666   0.053  -0.116  -0.558
242   I         0.433   0.391  -0.011   0.613   0.559  -0.070   0.520   0.454  -0.150
243   A        -0.532  -0.531  -0.608  -0.610  -0.569  -0.637  -0.647  -0.624  -0.668
244   L        -0.110  -0.089  -0.139  -0.414  -0.404  -0.393  -0.356  -0.342  -0.366
245   I        -0.311  -0.288  -0.564  -0.270  -0.225  -0.606  -0.297  -0.256  -0.608
246   L        -0.706  -0.764  -0.661  -0.787  -0.876  -0.750  -0.822  -0.860  -0.726
247   V        -0.922  -0.894  -1.008  -1.001  -0.970  -1.068  -0.881  -0.843  -0.888
248   A        -0.311  -0.324  -0.544  -0.340  -0.368  -0.707  -0.297  -0.310  -0.580
249   A        -0.316  -0.259  -0.204  -0.562  -0.458  -0.398  -0.589  -0.521  -0.445
250   Y         0.338   0.410   0.480   0.214   0.335   0.430  -0.006   0.124   0.188
251   K         0.338   0.332   0.440   0.264   0.239   0.396  -0.006  -0.032   0.107
252   G        -1.192  -1.114  -1.021  -1.117  -0.984  -0.863  -1.114  -1.028  -0.898
253   E        -1.139  -1.049  -1.049  -0.924  -0.799  -0.816  -1.056  -0.959  -0.924
254   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
255   E        -0.408  -0.362  -0.231  -0.600  -0.511  -0.343  -0.706  -0.643  -0.480
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   Y        -2.004  -2.018  -1.839  -1.612  -1.635  -1.435  -1.406  -1.393  -1.198
262   A        -0.965  -0.922  -1.012  -0.896  -0.855  -0.922  -0.881  -0.847  -0.889
263   N        -1.057  -1.017  -1.033  -1.055  -0.999  -0.950  -0.997  -0.936  -0.909
264   S        -1.490  -1.490  -1.351  -1.331  -1.320  -1.167  -1.231  -1.216  -1.043
265   G        -0.729  -0.765  -0.686  -1.159  -1.226  -1.123  -0.821  -0.853  -0.749
266   A        -0.517  -0.426  -0.636  -0.516  -0.393  -0.685  -0.533  -0.414  -0.690
267   E        -0.261  -0.338  -0.210  -0.302  -0.404  -0.228  -0.533  -0.614  -0.453
268   C         1.463   1.487   1.563   1.726   1.765   1.874   1.628   1.660   1.787
269   D        -0.729  -0.784  -0.685  -0.860  -0.946  -0.825  -0.821  -0.872  -0.749
270   A        -1.197  -1.106  -1.050  -1.409  -1.297  -1.150  -1.109  -1.013  -0.924
271   R        -1.197  -1.113  -1.050  -1.171  -1.036  -1.001  -1.109  -1.021  -0.924
272   C         1.463   1.487   1.563   1.726   1.765   1.874   1.628   1.660   1.787
273   Q        -0.706  -0.717  -0.671  -0.579  -0.582  -0.545  -0.822  -0.808  -0.737
274   K        -1.355  -1.392  -1.341  -1.048  -1.114  -1.019  -1.114  -1.134  -1.035
275   A         0.338   0.332   0.440   0.088   0.071   0.246  -0.006  -0.032   0.107
276   C        -0.461  -0.457  -0.587  -0.487  -0.468  -0.650  -0.531  -0.496  -0.638
277   D        -0.013  -0.090  -0.144   0.111   0.023  -0.073  -0.181  -0.271  -0.357
278   Q        -0.706  -0.668  -0.675  -0.778  -0.754  -0.678  -0.822  -0.778  -0.741
279   M        -0.316  -0.263  -0.202  -0.363  -0.296  -0.212  -0.589  -0.526  -0.442
280   W         1.463   1.487   1.563   1.727   1.759   1.875   1.628   1.660   1.787
281   R         1.463   1.487   1.563   1.644   1.676   1.797   1.628   1.660   1.787
282   I        -0.013  -0.088  -0.118  -0.231  -0.324  -0.372  -0.181  -0.268  -0.319
283   L        -0.706  -0.680  -0.674  -0.826  -0.759  -0.786  -0.822  -0.787  -0.740
284   I        -0.759  -0.763  -0.677  -0.946  -0.946  -0.779  -0.881  -0.874  -0.743
285   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
286   L        -1.057  -1.116  -1.012  -1.142  -1.222  -1.064  -0.997  -1.021  -0.890
287   G         0.338   0.332   0.440  -0.103  -0.128   0.048  -0.006  -0.032   0.107
288   T        -0.706  -0.665  -0.674  -0.801  -0.779  -0.765  -0.822  -0.776  -0.740
289   V         0.940   0.848   0.639   1.079   0.972   0.660   1.045   0.901   0.502
290   L         0.940   1.011   0.654   1.206   1.292   0.773   1.045   1.145   0.530
291   G         0.280   0.309   0.435  -0.207  -0.160   0.051  -0.122  -0.080   0.096
292   L        -1.273  -1.254  -1.061  -1.353  -1.308  -1.059  -1.172  -1.143  -0.934
293   A        -0.965  -0.880  -0.969  -1.143  -1.001  -1.146  -0.881  -0.777  -0.846
294   C        -0.532  -0.445  -0.626  -0.670  -0.566  -0.749  -0.647  -0.564  -0.689
295   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
296   Y         0.338   0.332   0.440   0.204   0.171   0.311  -0.006  -0.032   0.107
297   F        -0.408  -0.381  -0.238  -0.496  -0.441  -0.239  -0.706  -0.666  -0.490
298   R         1.463   1.487   1.563   1.644   1.676   1.797   1.628   1.660   1.787
299   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
300   T        -0.057  -0.122  -0.516   0.240   0.164  -0.406   0.053  -0.031  -0.543
301   I         0.338   0.332   0.440   0.112   0.107   0.280  -0.006  -0.032   0.107
302   P        -0.965  -0.993  -1.012  -0.735  -0.756  -0.819  -0.881  -0.894  -0.888
303   E         1.463   1.487   1.563   1.599   1.632   1.755   1.628   1.660   1.787
304   S         0.338   0.358   0.434   0.171   0.197   0.293  -0.006   0.019   0.094
305   P        -0.311  -0.388  -0.601   0.032  -0.070  -0.393  -0.297  -0.388  -0.651
306   R        -0.311  -0.388  -0.601  -0.001  -0.098  -0.432  -0.297  -0.388  -0.651
307   Y         0.649   0.603   0.522   0.831   0.756   0.569   0.578   0.486   0.274
308   Q        -1.490  -1.424  -1.348  -1.354  -1.269  -1.114  -1.231  -1.171  -1.041
309   L        -0.759  -0.764  -0.679  -0.923  -0.907  -0.733  -0.881  -0.874  -0.746
310   D         0.338   0.332   0.440   0.251   0.228   0.376  -0.006  -0.032   0.107
311   V        -0.013  -0.029  -0.152   0.023  -0.019  -0.151  -0.181  -0.225  -0.374
312   N        -1.571  -1.537  -1.353  -1.453  -1.399  -1.124  -1.289  -1.247  -1.044
313   A        -1.110  -1.111  -1.041  -1.120  -1.105  -0.979  -1.056  -1.039  -0.918
314   -        -0.261  -0.260  -0.206  -0.262  -0.239  -0.172  -0.533  -0.517  -0.447
315   -        -0.729  -0.755  -0.678  -0.845  -0.891  -0.768  -0.821  -0.844  -0.741
316   -        -1.069  -0.942  -1.038  -0.975  -0.761  -0.997  -0.965  -0.824  -0.911
317   -        -1.537  -1.492  -1.370  -1.390  -1.334  -1.183  -1.253  -1.206  -1.056
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   K        -2.004  -1.992  -1.817  -1.565  -1.554  -1.356  -1.406  -1.377  -1.185
320   L        -1.922  -1.873  -1.799  -1.651  -1.583  -1.550  -1.347  -1.297  -1.175
321   E         0.940   1.011   0.654   1.194   1.286   0.808   1.045   1.145   0.530
322   L        -0.667  -0.664  -0.631  -0.888  -0.881  -0.807  -0.764  -0.751  -0.691
323   A        -1.355  -1.302  -1.310  -1.081  -1.011  -1.022  -1.114  -1.062  -1.012
324   A        -1.057  -1.069  -1.006  -1.092  -1.128  -1.051  -0.997  -0.999  -0.889
325   A        -1.490  -1.414  -1.314  -1.467  -1.378  -1.209  -1.231  -1.157  -1.015
326   A        -2.014  -2.025  -1.835  -2.006  -2.005  -1.778  -1.408  -1.396  -1.196
327   Q        -1.448  -1.400  -1.323  -1.179  -1.110  -1.009  -1.196  -1.144  -1.023
328   E        -1.416  -1.431  -1.342  -1.628  -1.653  -1.499  -1.161  -1.157  -1.035
329   Q        -0.542  -0.572  -0.587  -0.393  -0.416  -0.425  -0.631  -0.647  -0.646
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   K        -1.512  -1.508  -1.368  -1.313  -1.308  -1.119  -1.240  -1.221  -1.055
362   I        -0.987  -0.963  -0.976  -0.989  -0.927  -1.022  -0.899  -0.863  -0.857
363   H        -1.680  -1.635  -1.560  -1.282  -1.209  -1.181  -1.248  -1.201  -1.094
364   D        -1.151  -1.201  -1.055  -1.224  -1.317  -1.150  -1.074  -1.097  -0.929
365   T        -1.780  -1.782  -1.597  -1.555  -1.533  -1.297  -1.335  -1.320  -1.121
366   S        -0.622  -0.594  -0.604  -0.577  -0.536  -0.531  -0.725  -0.696  -0.668
367   D        -0.380  -0.316  -0.552  -0.108  -0.015  -0.422  -0.357  -0.277  -0.588
368   E        -0.729  -0.691  -0.667  -0.647  -0.609  -0.566  -0.821  -0.787  -0.731
369   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
370   D        -1.512  -1.475  -1.338  -1.502  -1.449  -1.285  -1.240  -1.197  -1.032
371   M        -1.780  -1.720  -1.591  -1.541  -1.477  -1.288  -1.335  -1.276  -1.117
372   A        -1.780  -1.743  -1.594  -1.442  -1.382  -1.191  -1.335  -1.291  -1.119
373   I        -0.622  -0.556  -0.642  -0.835  -0.739  -0.879  -0.725  -0.653  -0.705
374   N        -0.804  -0.812  -0.681  -0.788  -0.792  -0.616  -0.909  -0.901  -0.746
375   G        -0.917  -0.861  -0.969  -0.878  -0.795  -1.002  -0.799  -0.730  -0.843
376   L        -0.917  -0.893  -1.031  -0.879  -0.840  -1.025  -0.799  -0.769  -0.904
377   E        -1.399  -1.392  -1.320  -1.101  -1.097  -1.013  -1.130  -1.113  -1.016
378   R        -0.692  -0.636  -0.636  -0.724  -0.637  -0.621  -0.799  -0.733  -0.699
379   A        -1.214  -1.177  -1.031  -1.225  -1.183  -0.956  -1.130  -1.084  -0.908
380   S        -1.214  -1.174  -1.060  -1.242  -1.179  -1.005  -1.130  -1.083  -0.932
381   T        -1.355  -1.367  -1.307  -1.188  -1.203  -1.146  -1.114  -1.110  -1.009
382   A        -1.355  -1.346  -1.316  -1.276  -1.252  -1.188  -1.114  -1.087  -1.014
383   V        -1.408  -1.475  -1.329  -1.559  -1.617  -1.391  -1.172  -1.198  -1.026
384   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   E        -1.057  -1.086  -1.009  -0.904  -0.933  -0.840  -0.997  -1.012  -0.891
386   S        -1.355  -1.330  -1.310  -1.143  -1.113  -1.091  -1.114  -1.084  -1.013
387   L        -1.571  -1.574  -1.565  -1.256  -1.273  -1.325  -1.172  -1.170  -1.100
388   D        -1.706  -1.710  -1.583  -1.585  -1.584  -1.410  -1.289  -1.274  -1.111
389   N        -1.624  -1.618  -1.536  -1.402  -1.378  -1.257  -1.231  -1.210  -1.082
390   -        -1.538  -1.483  -1.340  -1.519  -1.436  -1.237  -1.266  -1.211  -1.037
391   -        -1.448  -1.479  -1.359  -1.313  -1.325  -1.142  -1.196  -1.198  -1.048
392   H        -1.922  -1.937  -1.804  -1.674  -1.721  -1.486  -1.347  -1.342  -1.178
393   P        -0.759  -0.908  -1.005  -0.464  -0.688  -0.929  -0.647  -0.799  -0.881
394   P        -0.057  -0.113  -0.507   0.369   0.293  -0.280   0.053  -0.023  -0.532
395   K         0.200   0.014  -0.112   0.433   0.109  -0.087   0.194  -0.128  -0.303
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   A         0.159   0.065  -0.076   0.190   0.076  -0.120   0.111  -0.014  -0.252
399   S        -0.013  -0.090  -0.144   0.027  -0.070  -0.161  -0.181  -0.271  -0.357
400   F        -1.571  -1.606  -1.579  -1.316  -1.384  -1.374  -1.172  -1.193  -1.110
401   K        -0.706  -0.666  -0.671  -0.812  -0.772  -0.786  -0.822  -0.777  -0.737
402   D        -0.461  -0.493  -0.618  -0.412  -0.456  -0.636  -0.531  -0.562  -0.673
403   F         1.463   1.487   1.563   1.513   1.545   1.673   1.628   1.660   1.787
404   C        -1.408  -1.392  -1.338  -1.242  -1.244  -1.092  -1.172  -1.148  -1.034
405   R        -1.273  -1.234  -1.289  -0.986  -0.939  -0.993  -1.056  -1.012  -0.996
406   H         0.338   0.332   0.440   0.405   0.385   0.527  -0.006  -0.032   0.107
407   F         0.940   0.851   0.638   1.087   0.988   0.698   1.045   0.906   0.500
408   G        -0.667  -0.730  -0.636  -0.843  -0.911  -0.728  -0.764  -0.821  -0.700
409   Q         0.159   0.042  -0.107   0.454   0.301   0.028   0.111  -0.050  -0.304
410   W         0.940   0.851   0.638   1.299   1.198   0.886   1.045   0.906   0.500
411   K        -0.316  -0.304  -0.197  -0.296  -0.276  -0.114  -0.589  -0.571  -0.437
412   Y        -0.110  -0.138  -0.136   0.046   0.050   0.043  -0.356  -0.355  -0.350
413   G        -0.245  -0.319  -0.222  -0.593  -0.730  -0.588  -0.472  -0.577  -0.468
414   K         0.940   0.851   0.638   1.182   1.083   0.790   1.045   0.906   0.500
415   I        -0.245  -0.319  -0.222  -0.436  -0.568  -0.450  -0.472  -0.577  -0.468
416   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
417   L        -0.013  -0.095  -0.131  -0.256  -0.375  -0.467  -0.181  -0.280  -0.352
418   G         0.940   0.933   0.654   0.858   0.855   0.458   1.045   1.031   0.529
419   T         0.940   0.848   0.639   1.096   0.988   0.680   1.045   0.901   0.502
420   A         0.649   0.685   0.588   0.581   0.631   0.472   0.578   0.630   0.403
421   G        -0.245  -0.319  -0.222  -0.601  -0.742  -0.608  -0.472  -0.577  -0.468
422   S         0.649   0.685   0.588   0.758   0.809   0.664   0.578   0.630   0.403
423   W         1.463   1.487   1.563   1.727   1.759   1.875   1.628   1.660   1.787
424   F         0.940   0.851   0.638   1.095   0.999   0.722   1.045   0.906   0.500
425   T        -0.965  -0.866  -0.986  -0.972  -0.854  -0.990  -0.881  -0.780  -0.864
426   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
427   D         1.463   1.487   1.563   1.626   1.665   1.780   1.628   1.660   1.787
428   V         0.280   0.333   0.450  -0.085   0.007   0.191  -0.122  -0.031   0.128
429   A         1.463   1.487   1.563   1.403   1.435   1.569   1.628   1.660   1.787
430   F         0.457   0.460   0.479   0.420   0.419   0.430   0.228   0.220   0.187
431   Y         1.463   1.487   1.563   1.661   1.696   1.813   1.628   1.660   1.787
432   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
433   L        -0.110  -0.189  -0.165  -0.380  -0.485  -0.434  -0.356  -0.445  -0.398
434   S        -0.408  -0.380  -0.237  -0.712  -0.642  -0.444  -0.706  -0.664  -0.489
435   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
436   N         1.463   1.487   1.563   1.623   1.657   1.777   1.628   1.660   1.787
437   S        -0.759  -0.688  -0.676  -0.711  -0.600  -0.584  -0.881  -0.800  -0.742
438   A        -0.110  -0.063  -0.139  -0.276  -0.208  -0.286  -0.356  -0.294  -0.361
439   V        -0.532  -0.435  -0.597  -0.564  -0.442  -0.612  -0.647  -0.547  -0.658
440   I         1.463   1.487   1.563   1.377   1.417   1.545   1.628   1.660   1.787
441   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
442   Q        -0.532  -0.546  -0.601  -0.344  -0.355  -0.382  -0.647  -0.651  -0.664
443   T        -0.965  -1.080  -1.016  -0.872  -1.026  -0.988  -0.881  -0.975  -0.895
444   I         0.940   0.848   0.639   0.955   0.861   0.587   1.045   0.901   0.502
445   G         0.940   1.009   0.657   0.893   0.975   0.566   1.045   1.141   0.535
446   Y         0.280   0.309   0.435   0.116   0.159   0.355  -0.122  -0.080   0.096
447   A        -0.706  -0.711  -0.650  -0.825  -0.796  -0.682  -0.822  -0.803  -0.713
448   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
449   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
450   G        -0.667  -0.653  -0.649  -0.858  -0.838  -0.782  -0.764  -0.746  -0.714
451   S        -0.311  -0.304  -0.554  -0.356  -0.337  -0.689  -0.297  -0.272  -0.593
452   K        -1.057  -1.059  -0.990  -0.935  -0.921  -0.833  -0.997  -0.976  -0.869
453   N         1.463   1.487   1.563   1.623   1.657   1.777   1.628   1.660   1.787
454   V        -0.706  -0.709  -0.668  -0.806  -0.775  -0.746  -0.822  -0.801  -0.732
455   Y         1.463   1.487   1.563   1.661   1.696   1.813   1.628   1.660   1.787
456   K        -1.490  -1.410  -1.318  -1.186  -1.072  -0.942  -1.231  -1.157  -1.017
457   K        -0.667  -0.659  -0.652  -0.724  -0.750  -0.740  -0.764  -0.761  -0.716
458   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
459   Y        -0.532  -0.547  -0.610  -0.311  -0.320  -0.369  -0.647  -0.654  -0.672
460   D        -0.667  -0.632  -0.628  -0.551  -0.495  -0.479  -0.764  -0.715  -0.688
461   T        -0.667  -0.662  -0.639  -0.663  -0.646  -0.663  -0.764  -0.742  -0.700
462   A         0.649   0.737   0.583   0.581   0.707   0.465   0.578   0.720   0.394
463   V        -0.316  -0.258  -0.188  -0.655  -0.561  -0.464  -0.589  -0.513  -0.424
464   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
465   N         1.463   1.487   1.563   1.623   1.657   1.777   1.628   1.660   1.787
466   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
467   I         1.463   1.487   1.563   1.377   1.417   1.545   1.628   1.660   1.787
468   L         0.280   0.299   0.432  -0.192  -0.165   0.058  -0.122  -0.100   0.089
469   I        -0.408  -0.358  -0.231  -0.805  -0.716  -0.532  -0.706  -0.637  -0.481
470   C        -0.461  -0.571  -0.636  -0.276  -0.456  -0.631  -0.531  -0.652  -0.697
471   A         1.463   1.487   1.563   1.403   1.435   1.569   1.628   1.660   1.787
472   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
473   S        -0.408  -0.380  -0.237  -0.604  -0.553  -0.365  -0.706  -0.665  -0.489
474   L        -0.408  -0.381  -0.232  -0.831  -0.773  -0.556  -0.706  -0.666  -0.483
475   P         1.463   1.487   1.563   1.660   1.691   1.812   1.628   1.660   1.787
476   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
477   Y         1.463   1.487   1.563   1.661   1.696   1.813   1.628   1.660   1.787
478   W         1.463   1.487   1.563   1.727   1.759   1.875   1.628   1.660   1.787
479   V        -1.057  -0.938  -0.989  -1.184  -0.994  -1.106  -0.997  -0.877  -0.867
480   S        -0.316  -0.289  -0.171  -0.448  -0.412  -0.233  -0.589  -0.554  -0.405
481   V         0.940   0.988   0.656   1.068   1.131   0.657   1.045   1.111   0.534
482   F        -0.245  -0.196  -0.174  -0.402  -0.327  -0.336  -0.472  -0.408  -0.403
483   T         0.338   0.332   0.440   0.083   0.046   0.203  -0.006  -0.032   0.107
484   V         0.457   0.457   0.450   0.325   0.316   0.225   0.228   0.214   0.128
485   D         0.338   0.332   0.440   0.283   0.263   0.412  -0.006  -0.032   0.107
486   I        -0.922  -0.951  -0.975  -0.976  -0.995  -1.001  -0.881  -0.892  -0.860
487   I        -0.667  -0.755  -0.671  -0.907  -1.013  -0.853  -0.764  -0.845  -0.736
488   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
489   R         1.463   1.487   1.563   1.644   1.676   1.797   1.628   1.660   1.787
490   K         1.463   1.487   1.563   1.604   1.637   1.760   1.628   1.660   1.787
491   P         0.338   0.332   0.440   0.376   0.356   0.512  -0.006  -0.032   0.107
492   I         1.463   1.487   1.563   1.377   1.417   1.545   1.628   1.660   1.787
493   Q         1.463   1.487   1.563   1.683   1.719   1.834   1.628   1.660   1.787
494   L        -0.706  -0.722  -0.640  -0.963  -0.973  -0.815  -0.822  -0.817  -0.705
495   A        -0.706  -0.665  -0.674  -0.798  -0.706  -0.719  -0.822  -0.776  -0.740
496   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
497   F         0.940   0.933   0.654   1.058   1.052   0.636   1.045   1.031   0.529
498   I        -1.408  -1.432  -1.322  -1.595  -1.649  -1.481  -1.172  -1.175  -1.023
499   I         0.940   0.988   0.656   0.921   0.989   0.514   1.045   1.111   0.534
500   L        -0.013  -0.090  -0.144  -0.142  -0.229  -0.268  -0.181  -0.271  -0.357
501   T        -0.461  -0.495  -0.616  -0.479  -0.517  -0.660  -0.531  -0.565  -0.671
502   A        -0.408  -0.381  -0.238  -0.915  -0.874  -0.649  -0.706  -0.666  -0.490
503   L        -0.013   0.025  -0.096  -0.126  -0.076  -0.239  -0.181  -0.134  -0.285
504   F         0.649   0.720   0.575   0.653   0.759   0.487   0.578   0.692   0.379
505   C        -0.461  -0.610  -0.638  -0.314  -0.539  -0.657  -0.531  -0.682  -0.697
506   V        -0.110  -0.070  -0.137  -0.367  -0.320  -0.375  -0.356  -0.324  -0.364
507   I        -0.316  -0.332  -0.230  -0.659  -0.675  -0.479  -0.589  -0.606  -0.480
508   G         0.338   0.332   0.440  -0.103  -0.128   0.048  -0.006  -0.032   0.107
509   F         0.338   0.332   0.440   0.036  -0.002   0.154  -0.006  -0.032   0.107
510   A        -1.057  -1.112  -1.029  -1.256  -1.315  -1.157  -0.997  -1.028  -0.906
511   Y         0.338   0.332   0.440   0.376   0.360   0.513  -0.006  -0.032   0.107
512   H        -1.408  -1.457  -1.316  -1.051  -1.103  -0.916  -1.172  -1.190  -1.016
513   K        -0.543  -0.658  -0.652  -0.362  -0.527  -0.535  -0.589  -0.720  -0.713
514   L         0.457   0.469   0.469   0.182   0.198   0.143   0.228   0.237   0.166
515   G        -0.461  -0.322  -0.566  -0.464  -0.249  -0.566  -0.531  -0.353  -0.617
516   D        -1.057  -1.019  -1.031  -0.916  -0.845  -0.838  -0.997  -0.938  -0.908
517   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
518   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
519   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
520   H        -0.110  -0.048  -0.139  -0.263  -0.185  -0.233  -0.356  -0.283  -0.361
521   G         0.940   0.851   0.638   0.858   0.751   0.431   1.045   0.906   0.500
522   L         0.338   0.332   0.440   0.076   0.062   0.242  -0.006  -0.032   0.107
523   L         0.338   0.332   0.440   0.006  -0.017   0.161  -0.006  -0.032   0.107
524   A         0.940   0.988   0.656   0.942   1.003   0.521   1.045   1.111   0.534
525   L        -0.110  -0.138  -0.136  -0.143  -0.134  -0.174  -0.356  -0.355  -0.350
526   Y        -0.142  -0.188  -0.148  -0.194  -0.243  -0.171  -0.414  -0.442  -0.373
527   V         0.159   0.137  -0.062   0.214   0.205  -0.170   0.111   0.098  -0.230
528   I         0.280   0.298   0.427  -0.191  -0.167   0.047  -0.122  -0.101   0.080
529   C         0.280   0.336   0.450   0.083   0.156   0.338  -0.122  -0.024   0.126
530   Q         1.463   1.487   1.563   1.683   1.719   1.834   1.628   1.660   1.787
531   F         0.338   0.391   0.453   0.064   0.163   0.218  -0.006   0.087   0.133
532   F         1.463   1.487   1.563   1.513   1.545   1.673   1.628   1.660   1.787
533   Q        -0.841  -0.841  -0.695  -0.822  -0.847  -0.650  -0.939  -0.935  -0.759
534   N         1.463   1.487   1.563   1.623   1.657   1.777   1.628   1.660   1.787
535   F         1.463   1.487   1.563   1.513   1.545   1.673   1.628   1.660   1.787
536   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
537   P         1.463   1.487   1.563   1.660   1.691   1.812   1.628   1.660   1.787
538   N         1.463   1.487   1.563   1.623   1.657   1.777   1.628   1.660   1.787
539   T        -0.748  -0.727  -0.655  -0.835  -0.818  -0.757  -0.822  -0.795  -0.716
540   T         1.463   1.487   1.563   1.533   1.567   1.692   1.628   1.660   1.787
541   T         0.940   0.848   0.639   1.116   1.017   0.742   1.045   0.901   0.502
542   F         1.463   1.487   1.563   1.513   1.545   1.673   1.628   1.660   1.787
543   I         0.433   0.317  -0.016   0.481   0.344  -0.175   0.520   0.357  -0.158
544   V        -0.013  -0.090  -0.144   0.005  -0.095  -0.209  -0.181  -0.271  -0.357
545   P         1.463   1.487   1.563   1.660   1.691   1.812   1.628   1.660   1.787
546   G         0.338   0.332   0.440  -0.103  -0.128   0.048  -0.006  -0.032   0.107
547   E         1.463   1.487   1.563   1.599   1.632   1.755   1.628   1.660   1.787
548   C         0.457   0.536   0.495   0.454   0.577   0.498   0.228   0.363   0.219
549   F         0.940   1.016   0.656   1.087   1.176   0.727   1.045   1.151   0.534
550   P         1.463   1.487   1.563   1.660   1.691   1.812   1.628   1.660   1.787
551   T        -0.013  -0.090  -0.144  -0.065  -0.167  -0.271  -0.181  -0.271  -0.357
552   R         1.463   1.487   1.563   1.644   1.676   1.797   1.628   1.660   1.787
553   Y         0.338   0.332   0.440   0.274   0.246   0.393  -0.006  -0.032   0.107
554   R         1.463   1.487   1.563   1.644   1.676   1.797   1.628   1.660   1.787
555   S        -0.013  -0.090  -0.144  -0.117  -0.228  -0.362  -0.181  -0.271  -0.357
556   T        -0.013  -0.032  -0.108  -0.014  -0.006  -0.152  -0.181  -0.171  -0.306
557   A         0.649   0.532   0.471   0.581   0.391   0.260   0.578   0.357   0.171
558   H         1.463   1.487   1.563   1.731   1.768   1.880   1.628   1.660   1.787
559   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
560   I        -0.013  -0.027  -0.122  -0.233  -0.276  -0.413  -0.181  -0.218  -0.340
561   S         0.940   0.848   0.639   1.119   1.020   0.745   1.045   0.901   0.502
562   A         1.463   1.487   1.563   1.403   1.435   1.569   1.628   1.660   1.787
563   A         1.463   1.487   1.563   1.403   1.435   1.569   1.628   1.660   1.787
564   S        -1.192  -1.212  -1.051  -1.268  -1.260  -0.992  -1.114  -1.110  -0.926
565   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
566   K         1.463   1.487   1.563   1.604   1.637   1.760   1.628   1.660   1.787
567   V        -0.667  -0.749  -0.670  -0.686  -0.805  -0.744  -0.764  -0.839  -0.734
568   G         1.463   1.487   1.563   1.310   1.345   1.482   1.628   1.660   1.787
569   A         0.940   0.851   0.638   0.965   0.860   0.559   1.045   0.906   0.500
570   I         1.463   1.487   1.563   1.377   1.417   1.545   1.628   1.660   1.787
571   I         0.338   0.332   0.440  -0.061  -0.087   0.079  -0.006  -0.032   0.107
572   A         0.433   0.241  -0.033   0.503   0.253  -0.195   0.520   0.252  -0.185
573   Q        -0.013  -0.090  -0.144   0.112   0.006  -0.131  -0.181  -0.271  -0.357
574   T        -0.706  -0.709  -0.668  -0.950  -0.961  -0.907  -0.822  -0.801  -0.732
575   A        -0.841  -0.763  -0.686  -1.082  -0.979  -0.831  -0.939  -0.848  -0.750
576   L        -0.316  -0.259  -0.204  -0.671  -0.579  -0.511  -0.589  -0.521  -0.445
577   G        -0.110  -0.188  -0.174  -0.361  -0.448  -0.416  -0.356  -0.443  -0.408
578   T        -0.461  -0.610  -0.638  -0.387  -0.573  -0.596  -0.531  -0.682  -0.697
579   L         1.463   1.487   1.563   1.366   1.396   1.534   1.628   1.660   1.787
580   I        -0.706  -0.715  -0.671  -0.881  -0.845  -0.778  -0.822  -0.807  -0.737
581   D        -1.408  -1.479  -1.339  -1.243  -1.330  -1.175  -1.172  -1.205  -1.035
582   H         0.759   0.599   0.520   1.070   0.842   0.670   0.764   0.480   0.269
583   N         0.291   0.298   0.427   0.037   0.013   0.211  -0.101  -0.101   0.079
584   C         0.759   0.599   0.520   1.034   0.780   0.562   0.764   0.480   0.269
585   A        -0.517  -0.588  -0.653  -0.554  -0.685  -0.772  -0.533  -0.630  -0.710
586   R        -0.177  -0.184  -0.200  -0.137  -0.179  -0.247  -0.389  -0.424  -0.440
587   D         0.096  -0.034  -0.160   0.257   0.030  -0.230   0.043  -0.160  -0.375
588   G         0.096   0.165  -0.136   0.042   0.139  -0.286   0.043   0.141  -0.339
589   K         0.759   0.599   0.520   0.964   0.736   0.579   0.764   0.480   0.269
590   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
591   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
592   N        -0.667  -0.624  -0.650  -0.736  -0.675  -0.769  -0.764  -0.719  -0.713
593   C        -0.110  -0.188  -0.174  -0.098  -0.215  -0.177  -0.356  -0.443  -0.408
594   W        -0.316  -0.273  -0.206  -0.468  -0.428  -0.323  -0.589  -0.537  -0.447
595   L        -0.461  -0.610  -0.638  -0.479  -0.656  -0.660  -0.531  -0.682  -0.697
596   P        -0.408  -0.380  -0.237  -0.642  -0.621  -0.381  -0.706  -0.665  -0.489
597   H         0.338   0.332   0.440   0.387   0.363   0.506  -0.006  -0.032   0.107
598   V         1.463   1.487   1.563   1.519   1.554   1.679   1.628   1.660   1.787
599   M         0.457   0.399   0.438   0.487   0.347   0.322   0.228   0.102   0.103
600   E         0.338   0.332   0.440   0.324   0.307   0.467  -0.006  -0.032   0.107
601   I         1.463   1.487   1.563   1.377   1.417   1.545   1.628   1.660   1.787
602   F         0.940   0.851   0.638   1.087   0.988   0.698   1.045   0.906   0.500
603   A        -0.013  -0.090  -0.144  -0.054  -0.146  -0.216  -0.181  -0.271  -0.357
604   L         0.338   0.332   0.440  -0.101  -0.135   0.035  -0.006  -0.032   0.107
605   F         0.338   0.332   0.440   0.253   0.242   0.408  -0.006  -0.032   0.107
606   M         1.463   1.487   1.563   1.691   1.724   1.842   1.628   1.660   1.787
607   L        -0.013  -0.090  -0.144  -0.091  -0.186  -0.247  -0.181  -0.271  -0.357
608   L        -0.883  -0.876  -0.995  -1.077  -1.085  -1.204  -0.822  -0.811  -0.873
609   G         0.940   0.933   0.654   0.858   0.855   0.458   1.045   1.031   0.529
610   I        -0.057  -0.197  -0.526   0.046  -0.139  -0.651   0.053  -0.130  -0.556
611   F        -0.667  -0.723  -0.623  -0.901  -0.988  -0.850  -0.764  -0.809  -0.684
612   T        -0.841  -0.816  -0.690  -1.034  -0.993  -0.832  -0.939  -0.905  -0.754
613   T         0.457   0.546   0.509   0.395   0.543   0.443   0.228   0.382   0.247
614   L         0.338   0.360   0.447   0.006   0.036   0.173  -0.006   0.025   0.121
615   L         0.940   0.848   0.639   0.911   0.796   0.476   1.045   0.901   0.502
616   I         0.338   0.332   0.440  -0.061  -0.087   0.079  -0.006  -0.032   0.107
617   P         1.463   1.487   1.563   1.660   1.691   1.812   1.628   1.660   1.787
618   E         1.463   1.487   1.563   1.599   1.632   1.755   1.628   1.660   1.787
619   T         1.463   1.487   1.563   1.533   1.567   1.692   1.628   1.660   1.787
620   K         0.649   0.610   0.487   0.752   0.682   0.396   0.578   0.499   0.203
621   R        -0.311  -0.400  -0.595  -0.057  -0.163  -0.494  -0.297  -0.395  -0.643
622   K        -0.110  -0.038  -0.133  -0.049   0.039  -0.038  -0.356  -0.271  -0.355
623   T         0.338   0.332   0.440   0.215   0.199   0.358  -0.006  -0.032   0.107
624   L         0.338   0.332   0.440  -0.052  -0.082   0.092  -0.006  -0.032   0.107
625   E         0.338   0.332   0.440   0.273   0.253   0.408  -0.006  -0.032   0.107
626   E        -0.057  -0.052  -0.508   0.302   0.292  -0.350   0.053   0.053  -0.533
627   I         0.457   0.469   0.478   0.182   0.198   0.163   0.228   0.238   0.185
628   N        -0.706  -0.619  -0.659  -0.747  -0.615  -0.670  -0.822  -0.728  -0.724
629   E        -0.110  -0.188  -0.174  -0.116  -0.228  -0.231  -0.356  -0.443  -0.408
630   L        -1.273  -1.172  -1.259  -1.147  -1.030  -1.115  -1.056  -0.964  -0.974
631   Y        -0.729  -0.784  -0.685  -0.701  -0.783  -0.637  -0.821  -0.872  -0.749
632   H         0.759   0.599   0.520   1.062   0.831   0.650   0.764   0.480   0.269
633   D        -0.177  -0.253  -0.197  -0.368  -0.451  -0.351  -0.389  -0.480  -0.433
634   E         0.940   0.851   0.638   1.162   1.057   0.739   1.045   0.906   0.500
635   I        -0.706  -0.741  -0.614  -1.011  -1.056  -0.875  -0.822  -0.836  -0.677
636   D        -1.355  -1.442  -1.345  -1.145  -1.274  -1.198  -1.114  -1.164  -1.037
637   P        -2.004  -2.009  -1.839  -1.620  -1.636  -1.434  -1.406  -1.388  -1.198
638   A        -1.706  -1.700  -1.612  -1.643  -1.612  -1.458  -1.289  -1.264  -1.131
639   T        -1.355  -1.408  -1.306  -1.204  -1.288  -1.154  -1.114  -1.141  -1.006
640   L        -1.139  -1.151  -1.040  -1.098  -1.089  -0.890  -1.056  -1.059  -0.916
641   N        -0.082  -0.082  -0.145  -0.288  -0.284  -0.365  -0.247  -0.247  -0.358
642   F        -1.358  -1.247  -1.298  -1.038  -0.897  -0.928  -1.125  -1.023  -1.001
643   R        -0.517  -0.571  -0.631  -0.295  -0.427  -0.513  -0.533  -0.635  -0.684
644   N        -1.809  -1.719  -1.622  -1.509  -1.430  -1.282  -1.350  -1.277  -1.137
645   K        -2.106  -1.958  -1.846  -1.906  -1.779  -1.559  -1.460  -1.349  -1.202
646   N        -1.922  -1.915  -1.793  -1.715  -1.753  -1.563  -1.347  -1.329  -1.171
647   N        -1.706  -1.649  -1.571  -1.368  -1.286  -1.158  -1.289  -1.233  -1.107
648   D        -2.014  -1.967  -1.834  -1.609  -1.513  -1.394  -1.408  -1.362  -1.195
649   I        -2.220  -2.141  -2.004  -1.753  -1.622  -1.490  -1.464  -1.399  -1.231
650   E        -1.408  -1.417  -1.314  -1.234  -1.240  -1.105  -1.172  -1.160  -1.014
651   S        -1.416  -1.401  -1.346  -1.253  -1.226  -1.182  -1.161  -1.133  -1.039
652   S        -1.251  -1.212  -1.328  -0.767  -0.716  -0.949  -0.987  -0.944  -1.023
653   S        -0.857  -0.852  -0.704  -0.928  -0.915  -0.729  -0.965  -0.942  -0.769
654   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
655   P        -0.870  -0.923  -0.979  -0.724  -0.799  -0.910  -0.772  -0.812  -0.854
656   S        -0.734  -0.680  -0.667  -0.639  -0.555  -0.562  -0.843  -0.774  -0.731
657   Q        -1.273  -1.231  -1.317  -0.955  -0.897  -0.955  -1.056  -1.012  -1.016
658   L        -2.004  -1.988  -1.814  -1.831  -1.819  -1.584  -1.406  -1.377  -1.184
659   Q        -1.624  -1.624  -1.597  -1.259  -1.262  -1.212  -1.231  -1.217  -1.122
660   H        -1.139  -1.045  -1.044  -1.236  -1.120  -1.082  -1.056  -0.957  -0.919
661   E        -1.355  -1.277  -1.336  -1.264  -1.147  -1.166  -1.114  -1.025  -1.030
662   A        -1.120  -1.058  -1.046  -1.158  -1.092  -1.013  -1.055  -0.991  -0.922
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25297
Output conservation file - output/P25297
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
