1     M         1.093   1.116   1.177   1.241   1.272   1.357   1.156   1.189   1.278
2     S         0.016  -0.007   0.041   0.024  -0.024   0.032  -0.247  -0.300  -0.257
3     E        -0.098   0.023   0.064  -0.305  -0.071  -0.055  -0.455  -0.246  -0.214
4     T        -1.597  -1.413  -1.457  -1.428  -1.167  -1.238  -1.421  -1.223  -1.200
5     -        -1.301  -1.275  -1.119  -1.376  -1.334  -1.106  -1.326  -1.277  -1.068
6     E        -1.597  -1.666  -1.500  -1.610  -1.731  -1.498  -1.421  -1.454  -1.236
7     L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
8     R        -1.168  -1.268  -1.115  -1.239  -1.368  -1.133  -1.206  -1.272  -1.064
9     -        -1.306  -1.315  -1.136  -1.362  -1.366  -1.094  -1.318  -1.317  -1.084
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    K        -1.285  -1.293  -1.116  -1.385  -1.343  -1.091  -1.314  -1.296  -1.065
14    R        -0.840  -0.867  -1.054  -0.614  -0.671  -1.012  -0.777  -0.813  -0.998
15    Q        -0.098   0.023   0.064  -0.250  -0.065  -0.001  -0.455  -0.246  -0.214
16    A        -1.403  -1.359  -1.461  -1.334  -1.266  -1.424  -1.206  -1.160  -1.202
17    Q        -1.091  -1.027  -1.072  -1.119  -1.023  -1.092  -1.099  -1.008  -1.020
18    F         0.414   0.289   0.147   0.535   0.367   0.122   0.404   0.207  -0.063
19    T        -1.091  -1.225  -1.104  -1.079  -1.285  -1.141  -1.099  -1.220  -1.053
20    R        -0.528  -0.522  -0.593  -0.619  -0.609  -0.730  -0.669  -0.665  -0.743
21    E        -1.168  -1.268  -1.115  -1.386  -1.492  -1.248  -1.206  -1.272  -1.064
22    L         0.414   0.282   0.149   0.476   0.310   0.126   0.404   0.196  -0.059
23    H         1.093   1.116   1.177   1.240   1.266   1.355   1.156   1.189   1.278
24    G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
25    D        -1.285  -1.232  -1.119  -1.496  -1.423  -1.217  -1.314  -1.254  -1.069
26    D        -2.133  -2.018  -1.818  -2.207  -2.039  -1.757  -1.707  -1.597  -1.351
27    I        -1.597  -1.397  -1.457  -1.634  -1.365  -1.431  -1.421  -1.209  -1.199
28    G        -1.698  -1.634  -1.492  -1.784  -1.696  -1.486  -1.509  -1.431  -1.229
29    K        -0.840  -0.806  -1.039  -0.752  -0.730  -1.060  -0.777  -0.747  -0.981
30    K        -0.840  -0.794  -1.039  -0.727  -0.695  -1.015  -0.777  -0.734  -0.982
31    T        -0.840  -0.884  -1.050  -0.588  -0.686  -0.927  -0.777  -0.834  -0.994
32    G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
33    L        -0.232  -0.291  -0.534  -0.131  -0.230  -0.584  -0.240  -0.331  -0.657
34    S        -1.597  -1.480  -1.478  -1.599  -1.496  -1.474  -1.421  -1.310  -1.219
35    A         1.093   1.116   1.177   0.947   0.985   1.091   1.156   1.189   1.278
36    L        -0.232  -0.341  -0.548  -0.122  -0.273  -0.589  -0.240  -0.392  -0.677
37    M        -1.597  -1.561  -1.474  -1.451  -1.464  -1.327  -1.421  -1.377  -1.215
38    S        -0.232  -0.278  -0.533  -0.061  -0.136  -0.577  -0.240  -0.315  -0.656
39    K         1.093   1.116   1.177   0.994   1.041   1.133   1.156   1.189   1.278
40    N        -0.840  -0.804  -1.048  -0.595  -0.566  -0.974  -0.777  -0.743  -0.991
41    N        -1.597  -1.601  -1.476  -1.542  -1.563  -1.352  -1.421  -1.405  -1.217
42    S        -1.091  -1.025  -1.080  -1.068  -0.986  -1.057  -1.099  -1.009  -1.027
43    A         0.414   0.289   0.147   0.340   0.176  -0.062   0.404   0.207  -0.063
44    Q        -0.232  -0.060  -0.514   0.060   0.277  -0.409  -0.240  -0.013  -0.630
45    K        -2.339  -2.190  -2.058  -2.114  -1.879  -1.756  -1.743  -1.614  -1.416
46    E        -1.597  -1.666  -1.500  -1.647  -1.712  -1.477  -1.421  -1.454  -1.236
47    A         0.414   0.289   0.147   0.343   0.180  -0.054   0.404   0.207  -0.063
48    V        -0.840  -0.804  -1.048  -0.731  -0.704  -1.075  -0.777  -0.743  -0.991
49    Q        -1.715  -1.591  -1.490  -1.727  -1.552  -1.400  -1.528  -1.408  -1.229
50    K        -0.856  -0.831  -0.658  -1.262  -1.220  -0.949  -1.099  -1.059  -0.823
51    Y         0.414   0.439   0.163   0.497   0.536   0.139   0.404   0.438  -0.035
52    L        -0.098   0.023   0.064  -0.285  -0.069  -0.036  -0.455  -0.246  -0.214
53    R        -0.661  -0.690  -0.605  -0.835  -0.859  -0.738  -0.884  -0.886  -0.760
54    N        -0.528  -0.564  -0.590  -0.351  -0.397  -0.480  -0.669  -0.697  -0.738
55    W         0.414   0.282   0.149   0.731   0.553   0.313   0.404   0.196  -0.059
56    D         0.414   0.439   0.163   0.441   0.472   0.051   0.404   0.438  -0.035
57    G        -0.840  -1.045  -1.083  -0.755  -1.048  -1.091  -0.777  -1.017  -1.029
58    R        -1.091  -1.014  -1.068  -1.161  -1.030  -1.091  -1.099  -1.000  -1.014
59    T        -1.403  -1.359  -1.461  -1.119  -1.077  -1.244  -1.206  -1.160  -1.202
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    D        -1.285  -1.262  -1.122  -1.360  -1.324  -1.118  -1.314  -1.276  -1.072
65    K        -1.403  -1.519  -1.474  -1.325  -1.498  -1.470  -1.206  -1.319  -1.213
66    D        -0.856  -0.824  -0.653  -1.226  -1.186  -0.917  -1.099  -1.051  -0.818
67    A        -0.098   0.023   0.064  -0.410  -0.186  -0.149  -0.455  -0.246  -0.214
68    E         0.080  -0.039   0.032  -0.068  -0.259  -0.152  -0.133  -0.359  -0.273
69    E        -1.597  -1.554  -1.466  -1.617  -1.562  -1.403  -1.421  -1.357  -1.208
70    R        -1.091  -1.104  -1.090  -1.088  -1.112  -1.160  -1.099  -1.090  -1.038
71    R         1.093   1.116   1.177   1.162   1.189   1.285   1.156   1.189   1.278
72    L        -0.528  -0.678  -0.617  -0.528  -0.756  -0.649  -0.669  -0.866  -0.774
73    E        -1.403  -1.460  -1.470  -1.309  -1.425  -1.419  -1.206  -1.267  -1.210
74    D        -0.232  -0.476  -0.567  -0.163  -0.532  -0.727  -0.240  -0.572  -0.702
75    Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
76    N        -1.285  -1.297  -1.124  -1.357  -1.409  -1.162  -1.314  -1.300  -1.073
77    E        -1.909  -1.926  -1.806  -1.743  -1.776  -1.575  -1.528  -1.530  -1.343
78    A        -1.091  -1.030  -1.082  -1.157  -1.053  -1.144  -1.099  -1.008  -1.029
79    T         0.414   0.289   0.147   0.538   0.365   0.122   0.404   0.207  -0.063
80    H        -1.403  -1.510  -1.476  -1.075  -1.260  -1.288  -1.206  -1.311  -1.215
81    S        -0.155  -0.113   0.019  -0.260  -0.198   0.003  -0.562  -0.498  -0.299
82    Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
83    Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
84    N         0.414   0.289   0.147   0.574   0.408   0.157   0.404   0.207  -0.063
85    V        -0.098   0.023   0.064  -0.370  -0.159  -0.113  -0.455  -0.246  -0.214
86    V         0.080  -0.039   0.032  -0.083  -0.326  -0.235  -0.133  -0.359  -0.273
87    T         1.093   1.116   1.177   1.137   1.166   1.262   1.156   1.189   1.278
88    D         1.093   1.116   1.177   1.049   1.081   1.183   1.156   1.189   1.278
89    F        -0.232  -0.476  -0.567  -0.033  -0.378  -0.546  -0.240  -0.572  -0.702
90    Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
91    E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
92    Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
93    G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
94    W         1.093   1.116   1.177   1.316   1.346   1.424   1.156   1.189   1.278
95    G         0.414   0.289   0.147   0.380   0.219   0.018   0.404   0.207  -0.063
96    S         0.080  -0.039   0.032   0.130  -0.072   0.024  -0.133  -0.359  -0.273
97    S         0.414   0.282   0.149   0.595   0.439   0.248   0.404   0.196  -0.059
98    F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
99    H         1.093   1.116   1.177   1.240   1.266   1.355   1.156   1.189   1.278
100   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
101   S         0.414   0.282   0.149   0.595   0.439   0.248   0.404   0.196  -0.059
102   R         1.093   1.116   1.177   1.162   1.189   1.285   1.156   1.189   1.278
103   F        -0.155  -0.113   0.019  -0.387  -0.322  -0.114  -0.562  -0.498  -0.299
104   Y        -0.232  -0.291  -0.534  -0.073  -0.156  -0.511  -0.240  -0.331  -0.657
105   K        -0.232  -0.277  -0.536  -0.145  -0.197  -0.548  -0.240  -0.315  -0.659
106   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
107   E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
108   S        -0.661  -0.554  -0.607  -0.840  -0.705  -0.703  -0.884  -0.761  -0.763
109   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
110   A        -1.597  -1.551  -1.483  -1.482  -1.467  -1.325  -1.421  -1.369  -1.223
111   A        -0.098   0.023   0.064  -0.233  -0.001   0.009  -0.455  -0.246  -0.214
112   S        -0.098  -0.064   0.030  -0.391  -0.337  -0.181  -0.455  -0.405  -0.278
113   I        -1.168  -1.014  -1.081  -1.077  -0.886  -0.933  -1.206  -1.041  -1.032
114   A         1.093   1.116   1.177   0.947   0.985   1.091   1.156   1.189   1.278
115   R         1.093   1.116   1.177   1.162   1.189   1.285   1.156   1.189   1.278
116   H         1.093   1.116   1.177   1.240   1.266   1.355   1.156   1.189   1.278
117   E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
118   H         0.414   0.535   0.174   0.671   0.808   0.331   0.404   0.575  -0.015
119   Y         0.080   0.200   0.108   0.027   0.212   0.046  -0.133   0.062  -0.133
120   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
121   A         1.093   1.116   1.177   0.947   0.985   1.091   1.156   1.189   1.278
122   Y        -0.528  -0.549  -0.578  -0.506  -0.538  -0.609  -0.669  -0.675  -0.718
123   K        -0.840  -0.973  -1.068  -0.668  -0.850  -0.944  -0.777  -0.943  -1.013
124   A        -0.661  -0.680  -0.606  -0.720  -0.690  -0.598  -0.884  -0.869  -0.759
125   G        -0.232  -0.060  -0.514  -0.169   0.036  -0.527  -0.240  -0.013  -0.630
126   I         0.414   0.517   0.172   0.585   0.706   0.211   0.404   0.550  -0.018
127   Q        -0.779  -0.633  -0.613  -0.889  -0.668  -0.636  -0.992  -0.789  -0.766
128   R        -1.285  -1.204  -1.119  -1.398  -1.282  -1.118  -1.314  -1.234  -1.069
129   G        -0.661  -0.693  -0.605  -0.841  -0.877  -0.728  -0.884  -0.889  -0.760
130   D        -0.661  -0.675  -0.609  -0.666  -0.642  -0.564  -0.884  -0.863  -0.762
131   L        -0.661  -0.675  -0.609  -0.871  -0.843  -0.736  -0.884  -0.863  -0.762
132   V         0.414   0.502   0.171   0.454   0.561   0.127   0.404   0.529  -0.021
133   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
134   D         1.093   1.116   1.177   1.049   1.081   1.183   1.156   1.189   1.278
135   V         1.093   1.116   1.177   1.030   1.064   1.166   1.156   1.189   1.278
136   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
137   C         1.093   1.116   1.177   1.332   1.361   1.439   1.156   1.189   1.278
138   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
139   V         1.093   1.116   1.177   1.030   1.064   1.166   1.156   1.189   1.278
140   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
141   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
142   P         1.093   1.116   1.177   1.235   1.262   1.351   1.156   1.189   1.278
143   A         0.414   0.517   0.172   0.338   0.473  -0.021   0.404   0.550  -0.018
144   R         1.093   1.116   1.177   1.162   1.189   1.285   1.156   1.189   1.278
145   E         0.080   0.202   0.102  -0.076   0.121  -0.052  -0.133   0.065  -0.145
146   I         1.093   1.116   1.177   1.182   1.208   1.303   1.156   1.189   1.278
147   A        -1.091  -0.983  -1.079  -1.087  -0.969  -1.006  -1.099  -0.989  -1.029
148   R        -0.232  -0.476  -0.567  -0.045  -0.413  -0.623  -0.240  -0.572  -0.702
149   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
150   T         1.093   1.116   1.177   1.137   1.166   1.262   1.156   1.189   1.278
151   G        -0.098  -0.071   0.029  -0.434  -0.403  -0.233  -0.455  -0.419  -0.280
152   C         0.080   0.022   0.045   0.211   0.078   0.029  -0.133  -0.247  -0.249
153   N        -0.840  -0.809  -1.046  -0.553  -0.517  -0.893  -0.777  -0.750  -0.990
154   V        -0.232  -0.235  -0.530  -0.008  -0.040  -0.499  -0.240  -0.262  -0.652
155   I        -0.661  -0.680  -0.606  -0.760  -0.769  -0.645  -0.884  -0.869  -0.759
156   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
157   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
158   N         1.093   1.116   1.177   1.170   1.206   1.292   1.156   1.189   1.278
159   N         1.093   1.116   1.177   1.170   1.206   1.292   1.156   1.189   1.278
160   N         1.093   1.116   1.177   1.170   1.206   1.292   1.156   1.189   1.278
161   D         1.093   1.116   1.177   1.049   1.081   1.183   1.156   1.189   1.278
162   Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
163   Q         1.093   1.116   1.177   1.246   1.276   1.361   1.156   1.189   1.278
164   I         0.414   0.439   0.163   0.583   0.609   0.189   0.404   0.438  -0.035
165   A        -1.597  -1.605  -1.491  -1.564  -1.573  -1.416  -1.421  -1.408  -1.229
166   K        -0.098   0.023   0.064  -0.284  -0.060  -0.036  -0.455  -0.246  -0.214
167   A        -0.232  -0.341  -0.548  -0.204  -0.334  -0.631  -0.240  -0.392  -0.677
168   K        -0.779  -0.711  -0.629  -0.862  -0.756  -0.667  -0.992  -0.907  -0.787
169   Y        -0.661  -0.675  -0.609  -0.645  -0.622  -0.542  -0.884  -0.863  -0.762
170   Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
171   A         0.414   0.439   0.163   0.366   0.405   0.032   0.404   0.438  -0.035
172   K        -1.091  -1.073  -1.098  -1.176  -1.190  -1.188  -1.099  -1.098  -1.049
173   K        -0.528  -0.544  -0.596  -0.603  -0.631  -0.704  -0.669  -0.701  -0.747
174   Y        -1.091  -1.179  -1.098  -1.024  -1.166  -1.018  -1.099  -1.187  -1.048
175   N        -1.285  -1.189  -1.116  -1.304  -1.204  -1.083  -1.314  -1.209  -1.066
176   L         0.414   0.439   0.163   0.460   0.492   0.108   0.404   0.438  -0.035
177   S        -1.091  -1.007  -1.077  -1.053  -0.963  -1.028  -1.099  -1.011  -1.028
178   D        -1.403  -1.470  -1.463  -1.239  -1.404  -1.365  -1.206  -1.275  -1.204
179   Q        -0.661  -0.562  -0.602  -0.727  -0.602  -0.582  -0.884  -0.774  -0.758
180   M        -1.091  -1.076  -1.075  -1.000  -0.969  -0.963  -1.099  -1.055  -1.021
181   D        -1.597  -1.654  -1.489  -1.524  -1.627  -1.399  -1.421  -1.443  -1.226
182   F         0.080   0.152   0.078   0.059   0.169   0.008  -0.133  -0.019  -0.189
183   V         1.093   1.116   1.177   1.030   1.064   1.166   1.156   1.189   1.278
184   K         1.093   1.116   1.177   0.994   1.041   1.133   1.156   1.189   1.278
185   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
186   D         1.093   1.116   1.177   1.049   1.081   1.183   1.156   1.189   1.278
187   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
188   M         1.093   1.116   1.177   1.241   1.272   1.357   1.156   1.189   1.278
189   K        -1.091  -1.020  -1.082  -0.901  -0.776  -0.898  -1.099  -1.003  -1.030
190   M         1.093   1.116   1.177   1.241   1.272   1.357   1.156   1.189   1.278
191   D        -1.091  -1.199  -1.094  -1.093  -1.210  -1.069  -1.099  -1.190  -1.043
192   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
193   E        -0.528  -0.515  -0.596  -0.590  -0.580  -0.673  -0.669  -0.680  -0.746
194   E        -1.285  -1.085  -1.098  -1.406  -1.096  -1.129  -1.314  -1.079  -1.047
195   N         0.080   0.200   0.108   0.062   0.260   0.053  -0.133   0.062  -0.133
196   T        -0.098  -0.064   0.030  -0.220  -0.173  -0.042  -0.455  -0.405  -0.278
197   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
198   D         1.093   1.116   1.177   1.049   1.081   1.183   1.156   1.189   1.278
199   K        -1.091  -1.030  -1.082  -1.214  -1.101  -1.171  -1.099  -1.008  -1.029
200   V         1.093   1.116   1.177   1.030   1.064   1.166   1.156   1.189   1.278
201   Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
202   A         1.093   1.116   1.177   0.947   0.985   1.091   1.156   1.189   1.278
203   I         1.093   1.116   1.177   1.182   1.208   1.303   1.156   1.189   1.278
204   E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
205   A         1.093   1.116   1.177   0.947   0.985   1.091   1.156   1.189   1.278
206   T         1.093   1.116   1.177   1.137   1.166   1.262   1.156   1.189   1.278
207   C        -0.098   0.023   0.064  -0.220  -0.044   0.028  -0.455  -0.246  -0.214
208   H         1.093   1.116   1.177   1.240   1.266   1.355   1.156   1.189   1.278
209   A         1.093   1.116   1.177   0.947   0.985   1.091   1.156   1.189   1.278
210   P         1.093   1.116   1.177   1.235   1.262   1.351   1.156   1.189   1.278
211   K        -1.168  -1.161  -1.101  -1.284  -1.260  -1.132  -1.206  -1.180  -1.051
212   L         0.414   0.502   0.171   0.460   0.567   0.121   0.404   0.529  -0.021
213   E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
214   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
215   V         1.093   1.116   1.177   1.030   1.064   1.166   1.156   1.189   1.278
216   Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
217   S        -0.155  -0.099   0.024  -0.460  -0.387  -0.179  -0.562  -0.471  -0.290
218   E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
219   I         1.093   1.116   1.177   1.182   1.208   1.303   1.156   1.189   1.278
220   Y         0.080   0.026   0.043   0.027  -0.070  -0.071  -0.133  -0.240  -0.253
221   K        -0.098  -0.113   0.019  -0.343  -0.364  -0.146  -0.455  -0.498  -0.298
222   V         1.093   1.116   1.177   1.030   1.064   1.166   1.156   1.189   1.278
223   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
224   K         1.093   1.116   1.177   0.994   1.041   1.133   1.156   1.189   1.278
225   P         1.093   1.116   1.177   1.235   1.262   1.351   1.156   1.189   1.278
226   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
227   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
228   T        -0.661  -0.578  -0.609  -0.757  -0.671  -0.653  -0.884  -0.791  -0.767
229   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
230   A        -0.098   0.023   0.064  -0.490  -0.271  -0.221  -0.455  -0.246  -0.214
231   V         1.093   1.116   1.177   1.030   1.064   1.166   1.156   1.189   1.278
232   Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
233   E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
234   W         1.093   1.116   1.177   1.316   1.346   1.424   1.156   1.189   1.278
235   V         0.414   0.282   0.149   0.434   0.255   0.040   0.404   0.196  -0.059
236   M         1.093   1.116   1.177   1.241   1.272   1.357   1.156   1.189   1.278
237   T         0.414   0.289   0.147   0.555   0.391   0.166   0.404   0.207  -0.063
238   D         0.414   0.535   0.174   0.442   0.594   0.076   0.404   0.575  -0.015
239   K        -1.091  -1.173  -1.098  -1.136  -1.250  -1.151  -1.099  -1.179  -1.049
240   Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
241   D         1.093   1.116   1.177   1.049   1.081   1.183   1.156   1.189   1.278
242   E        -0.840  -0.986  -1.070  -0.746  -0.942  -1.071  -0.777  -0.957  -1.016
243   N        -1.715  -1.649  -1.492  -1.639  -1.550  -1.345  -1.528  -1.445  -1.230
244   N         0.414   0.289   0.147   0.593   0.434   0.205   0.404   0.207  -0.063
245   P        -0.661  -0.686  -0.604  -0.740  -0.735  -0.651  -0.884  -0.878  -0.758
246   E         0.414   0.289   0.147   0.369   0.218  -0.032   0.404   0.207  -0.063
247   H         1.093   1.116   1.177   1.240   1.266   1.355   1.156   1.189   1.278
248   R         1.093   1.116   1.177   1.162   1.189   1.285   1.156   1.189   1.278
249   K        -0.528  -0.676  -0.617  -0.658  -0.892  -0.824  -0.669  -0.863  -0.774
250   I         1.093   1.116   1.177   1.182   1.208   1.303   1.156   1.189   1.278
251   A        -0.232  -0.347  -0.547  -0.169  -0.320  -0.553  -0.240  -0.401  -0.674
252   Y         0.414   0.282   0.149   0.485   0.310   0.083   0.404   0.196  -0.059
253   E        -1.168  -1.268  -1.115  -1.394  -1.512  -1.272  -1.206  -1.272  -1.064
254   I         1.093   1.116   1.177   1.182   1.208   1.303   1.156   1.189   1.278
255   E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
256   L        -0.661  -0.564  -0.593  -0.876  -0.707  -0.749  -0.884  -0.734  -0.741
257   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
258   D         0.414   0.282   0.149   0.471   0.301   0.103   0.404   0.196  -0.059
259   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
260   I         1.093   1.116   1.177   1.182   1.208   1.303   1.156   1.189   1.278
261   P         0.414   0.282   0.149   0.653   0.475   0.251   0.404   0.196  -0.059
262   K        -0.232  -0.476  -0.567  -0.137  -0.444  -0.575  -0.240  -0.572  -0.702
263   M         1.093   1.116   1.177   1.241   1.272   1.357   1.156   1.189   1.278
264   F        -0.779  -0.742  -0.639  -0.926  -0.907  -0.743  -0.992  -0.954  -0.800
265   H        -1.715  -1.647  -1.492  -1.631  -1.543  -1.291  -1.528  -1.449  -1.230
266   V        -1.168  -1.268  -1.115  -1.189  -1.317  -1.091  -1.206  -1.272  -1.064
267   D        -1.597  -1.641  -1.496  -1.561  -1.579  -1.383  -1.421  -1.439  -1.233
268   V        -0.840  -0.998  -1.070  -0.770  -1.030  -1.189  -0.777  -0.968  -1.015
269   A         0.414   0.282   0.149   0.338   0.159  -0.063   0.404   0.196  -0.059
270   R        -1.715  -1.644  -1.495  -1.812  -1.712  -1.496  -1.528  -1.442  -1.232
271   K        -1.597  -1.631  -1.478  -1.597  -1.681  -1.448  -1.421  -1.427  -1.218
272   A         1.093   1.116   1.177   0.947   0.985   1.091   1.156   1.189   1.278
273   L        -0.232  -0.476  -0.567  -0.087  -0.413  -0.535  -0.240  -0.572  -0.702
274   K        -0.232  -0.146  -0.518  -0.187  -0.062  -0.612  -0.240  -0.127  -0.635
275   N        -0.528  -0.478  -0.591  -0.477  -0.436  -0.614  -0.669  -0.625  -0.740
276   C         0.414   0.557   0.177   0.476   0.639   0.190   0.404   0.606  -0.009
277   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
278   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
279   E        -0.232  -0.341  -0.548  -0.191  -0.322  -0.642  -0.240  -0.392  -0.677
280   V        -0.779  -0.742  -0.639  -0.876  -0.865  -0.714  -0.992  -0.954  -0.800
281   L        -0.661  -0.724  -0.614  -0.916  -0.989  -0.813  -0.884  -0.937  -0.772
282   V        -1.285  -1.284  -1.120  -1.412  -1.384  -1.148  -1.314  -1.287  -1.069
283   S        -1.285  -1.252  -1.102  -1.292  -1.221  -0.998  -1.314  -1.250  -1.051
284   E        -1.597  -1.508  -1.465  -1.706  -1.553  -1.505  -1.421  -1.317  -1.208
285   D         1.093   1.116   1.177   1.049   1.081   1.183   1.156   1.189   1.278
286   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
287   A         0.414   0.289   0.147   0.364   0.207   0.001   0.404   0.207  -0.063
288   D         0.414   0.439   0.163   0.439   0.471   0.046   0.404   0.438  -0.035
289   N        -2.339  -2.270  -2.072  -2.103  -1.987  -1.777  -1.743  -1.670  -1.424
290   D        -0.232  -0.277  -0.536  -0.128  -0.193  -0.589  -0.240  -0.315  -0.659
291   D        -0.232  -0.341  -0.548  -0.133  -0.282  -0.620  -0.240  -0.392  -0.677
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   E        -0.528  -0.655  -0.610  -0.627  -0.795  -0.724  -0.669  -0.831  -0.764
294   I        -0.840  -1.045  -1.083  -0.551  -0.867  -0.963  -0.777  -1.017  -1.029
295   P         1.093   1.116   1.177   1.235   1.262   1.351   1.156   1.189   1.278
296   W         1.093   1.116   1.177   1.316   1.346   1.424   1.156   1.189   1.278
297   Y         1.093   1.116   1.177   1.081   1.119   1.212   1.156   1.189   1.278
298   Y        -0.232  -0.291  -0.534  -0.075  -0.143  -0.515  -0.240  -0.331  -0.657
299   P         1.093   1.116   1.177   1.235   1.262   1.351   1.156   1.189   1.278
300   L         0.414   0.282   0.149   0.467   0.296   0.103   0.404   0.196  -0.059
301   T        -0.779  -0.735  -0.637  -0.904  -0.872  -0.739  -0.992  -0.936  -0.798
302   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
303   E         0.080   0.060   0.050  -0.105  -0.135  -0.187  -0.133  -0.180  -0.241
304   W        -0.528  -0.653  -0.609  -0.317  -0.528  -0.512  -0.669  -0.829  -0.764
305   K        -0.232  -0.476  -0.567  -0.157  -0.479  -0.623  -0.240  -0.572  -0.702
306   Y        -0.232  -0.271  -0.537  -0.099  -0.166  -0.573  -0.240  -0.306  -0.661
307   V        -0.528  -0.656  -0.609  -0.463  -0.625  -0.528  -0.669  -0.831  -0.764
308   Q         0.414   0.502   0.171   0.667   0.772   0.305   0.404   0.529  -0.021
309   N        -0.779  -0.701  -0.623  -0.805  -0.689  -0.594  -0.992  -0.887  -0.779
310   L        -1.403  -1.470  -1.463  -1.226  -1.350  -1.339  -1.206  -1.275  -1.204
311   A        -2.027  -2.016  -1.804  -1.912  -1.866  -1.579  -1.636  -1.598  -1.342
312   N         0.414   0.557   0.177   0.471   0.639   0.149   0.404   0.606  -0.009
313   L        -1.715  -1.732  -1.500  -1.687  -1.711  -1.372  -1.528  -1.507  -1.236
314   A        -1.168  -1.048  -1.082  -1.296  -1.091  -1.130  -1.206  -1.063  -1.031
315   T         1.093   1.116   1.177   1.137   1.166   1.262   1.156   1.189   1.278
316   F        -0.856  -0.763  -0.639  -1.020  -0.895  -0.696  -1.099  -0.972  -0.799
317   F        -0.232  -0.347  -0.547  -0.071  -0.242  -0.600  -0.240  -0.401  -0.674
318   R         1.093   1.116   1.177   1.162   1.189   1.285   1.156   1.189   1.278
319   T         0.414   0.282   0.149   0.568   0.400   0.203   0.404   0.196  -0.059
320   S         0.414   0.282   0.149   0.567   0.396   0.176   0.404   0.196  -0.059
321   Y        -1.091  -1.024  -1.064  -0.977  -0.856  -0.950  -1.099  -1.003  -1.010
322   L        -1.403  -1.295  -1.443  -1.212  -1.091  -1.289  -1.206  -1.097  -1.186
323   G         0.414   0.282   0.149   0.350   0.165  -0.056   0.404   0.196  -0.059
324   R         0.414   0.289   0.147   0.558   0.383   0.130   0.404   0.207  -0.063
325   Q        -2.651  -2.522  -2.299  -2.312  -2.153  -1.852  -1.850  -1.740  -1.483
326   F        -0.856  -0.821  -0.655  -0.986  -0.953  -0.704  -1.099  -1.047  -0.820
327   T         0.414   0.282   0.149   0.540   0.357   0.131   0.404   0.196  -0.059
328   T        -1.403  -1.498  -1.473  -1.047  -1.202  -1.148  -1.206  -1.301  -1.213
329   A        -2.339  -2.262  -2.073  -2.178  -2.099  -1.793  -1.743  -1.665  -1.425
330   M        -1.597  -1.595  -1.489  -1.408  -1.429  -1.321  -1.421  -1.404  -1.227
331   V        -0.232  -0.347  -0.547  -0.149  -0.324  -0.628  -0.240  -0.401  -0.674
332   T        -1.091  -1.020  -1.082  -1.095  -0.989  -1.032  -1.099  -1.003  -1.030
333   V        -1.715  -1.685  -1.496  -1.742  -1.682  -1.420  -1.528  -1.472  -1.233
334   M        -0.661  -0.588  -0.608  -0.673  -0.622  -0.601  -0.884  -0.800  -0.764
335   E         1.093   1.116   1.177   0.973   1.023   1.115   1.156   1.189   1.278
336   K         0.414   0.282   0.149   0.411   0.253   0.044   0.404   0.196  -0.059
337   L        -0.856  -0.810  -0.655  -1.045  -0.979  -0.747  -1.099  -1.033  -0.820
338   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
339   L         0.080   0.068   0.051  -0.043  -0.078  -0.140  -0.133  -0.165  -0.239
340   A         1.093   1.116   1.177   0.947   0.985   1.091   1.156   1.189   1.278
341   P         0.414   0.289   0.147   0.625   0.444   0.175   0.404   0.207  -0.063
342   E        -0.528  -0.350  -0.570  -0.581  -0.326  -0.643  -0.669  -0.438  -0.710
343   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
344   S         0.080  -0.039   0.032   0.095  -0.125  -0.038  -0.133  -0.359  -0.273
345   K        -1.091  -1.098  -1.078  -1.134  -1.114  -1.085  -1.099  -1.083  -1.025
346   E        -1.285  -1.185  -1.118  -1.325  -1.204  -1.101  -1.314  -1.205  -1.068
347   V         0.414   0.282   0.149   0.447   0.275   0.075   0.404   0.196  -0.059
348   T        -0.232  -0.476  -0.567  -0.079  -0.458  -0.666  -0.240  -0.572  -0.702
349   A        -1.715  -1.578  -1.490  -1.755  -1.556  -1.407  -1.528  -1.384  -1.228
350   A         0.414   0.289   0.147   0.364   0.207   0.001   0.404   0.207  -0.063
351   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
352   E         0.080  -0.039   0.032  -0.139  -0.363  -0.278  -0.133  -0.359  -0.273
353   N        -1.597  -1.622  -1.492  -1.498  -1.523  -1.345  -1.421  -1.418  -1.229
354   A         0.414   0.282   0.149   0.338   0.159  -0.063   0.404   0.196  -0.059
355   A         0.414   0.289   0.147   0.381   0.232   0.044   0.404   0.207  -0.063
356   V        -0.232  -0.476  -0.567  -0.164  -0.520  -0.698  -0.240  -0.572  -0.702
357   G        -0.098  -0.021   0.044  -0.368  -0.248  -0.139  -0.455  -0.325  -0.251
358   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
359   V         0.414   0.289   0.147   0.454   0.294   0.088   0.404   0.207  -0.063
360   A        -0.155  -0.114   0.018  -0.603  -0.527  -0.309  -0.562  -0.500  -0.300
361   G         1.093   1.116   1.177   0.961   0.992   1.104   1.156   1.189   1.278
362   G         0.414   0.282   0.149   0.350   0.165  -0.056   0.404   0.196  -0.059
363   K        -0.856  -0.815  -0.654  -1.119  -1.067  -0.828  -1.099  -1.039  -0.819
364   S        -1.091  -1.014  -1.068  -1.040  -0.934  -0.983  -1.099  -1.000  -1.014
365   K         0.414   0.289   0.147   0.426   0.285   0.080   0.404   0.207  -0.063
366   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
367   F         1.093   1.116   1.177   1.132   1.166   1.258   1.156   1.189   1.278
368   T         1.093   1.116   1.177   1.137   1.166   1.262   1.156   1.189   1.278
369   P         1.093   1.116   1.177   1.235   1.262   1.351   1.156   1.189   1.278
370   M         1.093   1.116   1.177   1.241   1.272   1.357   1.156   1.189   1.278
371   M        -0.528  -0.650  -0.608  -0.373  -0.569  -0.550  -0.669  -0.823  -0.762
372   L         1.093   1.116   1.177   1.044   1.075   1.178   1.156   1.189   1.278
373   F        -0.779  -0.763  -0.642  -0.814  -0.790  -0.620  -0.992  -0.978  -0.804
374   V         0.414   0.289   0.147   0.454   0.294   0.088   0.404   0.207  -0.063
375   A        -1.403  -1.364  -1.461  -1.306  -1.292  -1.379  -1.206  -1.165  -1.202
376   R        -0.155  -0.099   0.024  -0.428  -0.345  -0.149  -0.562  -0.471  -0.290
377   K         1.093   1.116   1.177   0.994   1.041   1.133   1.156   1.189   1.278
378   P         1.093   1.116   1.177   1.235   1.262   1.351   1.156   1.189   1.278
379   E        -0.528  -0.476  -0.593  -0.685  -0.623  -0.810  -0.669  -0.622  -0.743
380   N        -1.597  -1.530  -1.465  -1.454  -1.361  -1.277  -1.421  -1.342  -1.208
381   A        -1.301  -1.275  -1.128  -1.595  -1.548  -1.328  -1.326  -1.284  -1.076
382   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
383   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
384   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
385   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   Q        -2.054  -1.980  -1.813  -1.937  -1.879  -1.586  -1.649  -1.571  -1.348
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P25087
Output conservation file - output/P25087
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
