1     M         1.292   1.307   1.361   1.414   1.429   1.511   1.403   1.424   1.508
2     N        -1.604  -1.512  -1.483  -1.375  -1.259  -1.190  -1.300  -1.221  -1.136
3     T        -1.316  -1.292  -1.196  -1.035  -1.002  -0.872  -1.184  -1.157  -1.028
4     S        -1.316  -1.273  -1.196  -1.301  -1.267  -1.145  -1.184  -1.139  -1.029
5     E        -0.934  -0.956  -0.857  -0.970  -0.982  -0.837  -0.992  -1.014  -0.884
6     L        -1.398  -1.369  -1.225  -1.517  -1.523  -1.255  -1.258  -1.225  -1.054
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    A        -0.398  -0.418  -0.363  -0.764  -0.808  -0.694  -0.630  -0.658  -0.575
14    E        -0.502  -0.414  -0.725  -0.202  -0.077  -0.540  -0.468  -0.356  -0.733
15    E         0.186   0.161   0.249   0.168   0.120   0.251  -0.156  -0.214  -0.090
16    I        -0.502  -0.640  -0.771  -0.283  -0.469  -0.634  -0.468  -0.637  -0.788
17    D         0.662   0.714   0.439   0.911   0.973   0.597   0.675   0.752   0.273
18    Y         1.292   1.307   1.361   1.404   1.418   1.502   1.403   1.424   1.508
19    E         1.292   1.307   1.361   1.397   1.420   1.495   1.403   1.424   1.508
20    A         0.062  -0.082  -0.252  -0.108  -0.312  -0.569   0.052  -0.153  -0.409
21    L         1.292   1.307   1.361   1.259   1.283   1.364   1.403   1.424   1.508
22    P         0.662   0.662   0.428   0.819   0.818   0.472   0.675   0.673   0.253
23    S        -1.205  -1.228  -1.177  -0.997  -1.034  -0.984  -1.092  -1.108  -1.014
24    H        -1.604  -1.567  -1.497  -1.229  -1.199  -1.081  -1.300  -1.264  -1.146
25    A        -0.502  -0.640  -0.771  -0.635  -0.837  -1.022  -0.468  -0.637  -0.788
26    P        -0.336  -0.333  -0.342  -0.465  -0.458  -0.462  -0.572  -0.564  -0.550
27    L        -0.502  -0.561  -0.735  -0.341  -0.418  -0.676  -0.468  -0.542  -0.745
28    H        -1.604  -1.638  -1.508  -1.595  -1.640  -1.447  -1.300  -1.314  -1.154
29    S        -1.025  -0.952  -1.135  -1.039  -0.939  -1.130  -0.884  -0.803  -0.971
30    Q        -0.517  -0.513  -0.398  -0.438  -0.421  -0.269  -0.780  -0.772  -0.619
31    L         0.352   0.323   0.297   0.301   0.257   0.204   0.156   0.096   0.005
32    L        -0.735  -0.696  -0.786  -0.885  -0.831  -0.994  -0.780  -0.737  -0.812
33    A         1.292   1.307   1.361   1.014   1.031   1.134   1.403   1.424   1.508
34    G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
35    A         1.292   1.307   1.361   1.014   1.031   1.134   1.403   1.424   1.508
36    F         0.662   0.706   0.435   0.803   0.861   0.468   0.675   0.740   0.267
37    A         0.662   0.565   0.422   0.444   0.312   0.098   0.675   0.519   0.242
38    G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
39    I         1.292   1.307   1.361   1.272   1.289   1.377   1.403   1.424   1.508
40    M         0.062  -0.082  -0.252   0.269   0.054  -0.274   0.052  -0.153  -0.409
41    E         1.292   1.307   1.361   1.397   1.420   1.495   1.403   1.424   1.508
42    H         1.292   1.307   1.361   1.481   1.501   1.574   1.403   1.424   1.508
43    S        -0.336  -0.360  -0.343  -0.524  -0.531  -0.459  -0.572  -0.589  -0.550
44    L        -0.502  -0.480  -0.732  -0.363  -0.350  -0.777  -0.468  -0.441  -0.742
45    M         0.662   0.748   0.438   0.858   0.962   0.523   0.675   0.803   0.272
46    F         0.186   0.161   0.249   0.112   0.059   0.196  -0.156  -0.214  -0.090
47    P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
48    I         0.186   0.184   0.256  -0.002  -0.019   0.098  -0.156  -0.168  -0.076
49    D         1.292   1.307   1.361   1.448   1.464   1.542   1.403   1.424   1.508
50    A         0.352   0.405   0.344  -0.019   0.066  -0.041   0.156   0.245   0.095
51    L        -0.336  -0.349  -0.327  -0.485  -0.484  -0.437  -0.572  -0.571  -0.530
52    K         1.292   1.307   1.361   1.357   1.383   1.457   1.403   1.424   1.508
53    T         1.292   1.307   1.361   1.261   1.282   1.366   1.403   1.424   1.508
54    R         1.292   1.307   1.361   1.449   1.463   1.544   1.403   1.424   1.508
55    V         0.062   0.191  -0.214   0.321   0.482  -0.098   0.052   0.229  -0.355
56    Q         1.292   1.307   1.361   1.438   1.465   1.534   1.403   1.424   1.508
57    A        -1.205  -1.177  -1.177  -1.237  -1.170  -1.211  -1.092  -1.055  -1.013
58    A        -1.604  -1.590  -1.484  -1.714  -1.672  -1.512  -1.300  -1.280  -1.137
59    G        -1.205  -1.179  -1.175  -1.182  -1.121  -1.109  -1.092  -1.070  -1.012
60    L        -1.298  -1.249  -1.190  -1.335  -1.261  -1.149  -1.177  -1.127  -1.025
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
63    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
64    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
65    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
66    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
67    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    N        -1.315  -1.311  -1.193  -1.331  -1.321  -1.137  -1.196  -1.183  -1.029
79    K        -1.205  -1.207  -1.171  -1.143  -1.146  -1.059  -1.092  -1.091  -1.009
80    A        -0.446  -0.450  -0.376  -0.832  -0.847  -0.708  -0.676  -0.684  -0.588
81    A        -1.205  -1.104  -1.169  -1.305  -1.110  -1.236  -1.092  -0.979  -1.005
82    S        -0.735  -0.682  -0.783  -0.840  -0.765  -0.926  -0.780  -0.730  -0.807
83    T        -1.604  -1.551  -1.480  -1.342  -1.271  -1.147  -1.300  -1.252  -1.134
84    G        -0.502  -0.531  -0.725  -0.359  -0.397  -0.707  -0.468  -0.507  -0.734
85    M        -0.916  -0.898  -0.836  -0.985  -0.977  -0.839  -0.988  -0.974  -0.864
86    I        -0.446  -0.455  -0.382  -0.596  -0.618  -0.510  -0.676  -0.691  -0.596
87    S        -1.205  -1.177  -1.162  -1.011  -0.935  -0.968  -1.092  -1.055  -1.000
88    Q        -0.336  -0.306  -0.329  -0.517  -0.464  -0.521  -0.572  -0.517  -0.527
89    I        -0.735  -0.784  -0.805  -0.728  -0.817  -0.839  -0.780  -0.842  -0.831
90    S         0.062  -0.082  -0.252   0.095  -0.095  -0.339   0.052  -0.153  -0.409
91    K        -0.213  -0.231  -0.322  -0.123  -0.147  -0.308  -0.364  -0.393  -0.519
92    I         1.292   1.307   1.361   1.272   1.289   1.377   1.403   1.424   1.508
93    S        -0.213  -0.154  -0.301  -0.450  -0.375  -0.619  -0.364  -0.297  -0.489
94    T        -0.213  -0.149  -0.278  -0.401  -0.287  -0.531  -0.364  -0.261  -0.450
95    M        -1.025  -0.904  -1.107  -0.932  -0.739  -1.096  -0.884  -0.748  -0.944
96    E         1.292   1.307   1.361   1.397   1.420   1.495   1.403   1.424   1.508
97    G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
98    S        -1.205  -1.245  -1.188  -1.323  -1.382  -1.289  -1.092  -1.123  -1.024
99    M        -1.205  -1.184  -1.178  -1.065  -1.021  -1.028  -1.092  -1.060  -1.013
100   A         0.133   0.157   0.251  -0.409  -0.352  -0.192  -0.260  -0.222  -0.085
101   L         1.292   1.307   1.361   1.259   1.283   1.364   1.403   1.424   1.508
102   W         1.292   1.307   1.361   1.538   1.558   1.628   1.403   1.424   1.508
103   K         0.186   0.246   0.277   0.166   0.274   0.292  -0.156  -0.047  -0.034
104   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
105   V        -0.213  -0.305  -0.338  -0.170  -0.327  -0.366  -0.364  -0.497  -0.540
106   Q         0.186   0.244   0.288  -0.030   0.067   0.134  -0.156  -0.052  -0.013
107   S         1.292   1.307   1.361   1.174   1.198   1.285   1.403   1.424   1.508
108   V         0.662   0.698   0.430   0.797   0.833   0.483   0.675   0.729   0.257
109   I         0.186   0.226   0.270  -0.002   0.059   0.123  -0.156  -0.087  -0.048
110   L        -0.735  -0.805  -0.805  -0.740  -0.852  -0.860  -0.780  -0.859  -0.833
111   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
112   A         1.292   1.307   1.361   1.014   1.031   1.134   1.403   1.424   1.508
113   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
114   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
115   A         0.662   0.565   0.422   0.444   0.312   0.098   0.675   0.519   0.242
116   H         1.292   1.307   1.361   1.481   1.501   1.574   1.403   1.424   1.508
117   A         1.292   1.307   1.361   1.014   1.031   1.134   1.403   1.424   1.508
118   V         0.186   0.187   0.260   0.018   0.002   0.115  -0.156  -0.163  -0.067
119   Y         1.292   1.307   1.361   1.404   1.418   1.502   1.403   1.424   1.508
120   F         1.292   1.307   1.361   1.359   1.379   1.459   1.403   1.424   1.508
121   G        -0.517  -0.494  -0.399  -1.004  -0.966  -0.794  -0.780  -0.749  -0.620
122   T         0.133   0.149   0.248  -0.107  -0.085   0.079  -0.260  -0.237  -0.092
123   Y        -0.213  -0.258  -0.300  -0.097  -0.156  -0.249  -0.364  -0.411  -0.482
124   E         1.292   1.307   1.361   1.397   1.420   1.495   1.403   1.424   1.508
125   F        -0.213  -0.189  -0.316  -0.283  -0.257  -0.524  -0.364  -0.338  -0.510
126   C        -1.205  -1.229  -1.182  -1.059  -1.085  -1.027  -1.092  -1.105  -1.017
127   K         1.292   1.307   1.361   1.357   1.383   1.457   1.403   1.424   1.508
128   A        -1.604  -1.588  -1.492  -1.598  -1.543  -1.413  -1.300  -1.278  -1.142
129   R        -1.894  -1.854  -1.742  -1.484  -1.429  -1.273  -1.404  -1.366  -1.222
130   L        -0.213  -0.322  -0.337  -0.210  -0.365  -0.393  -0.364  -0.512  -0.539
131   I        -0.398  -0.461  -0.382  -0.518  -0.615  -0.499  -0.630  -0.705  -0.597
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
137   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   S        -0.842  -0.903  -0.825  -0.891  -0.972  -0.857  -0.905  -0.958  -0.851
141   P        -1.629  -1.642  -1.512  -1.443  -1.468  -1.294  -1.313  -1.315  -1.156
142   E        -1.629  -1.620  -1.496  -1.258  -1.237  -1.065  -1.313  -1.299  -1.145
143   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   D        -1.205  -1.276  -1.200  -0.993  -1.087  -1.007  -1.092  -1.146  -1.033
145   M        -1.604  -1.638  -1.508  -1.561  -1.654  -1.458  -1.300  -1.314  -1.154
146   Q        -1.495  -1.493  -1.476  -1.101  -1.133  -1.105  -1.196  -1.192  -1.129
147   T        -0.336  -0.376  -0.337  -0.372  -0.391  -0.337  -0.572  -0.598  -0.539
148   H        -0.213  -0.258  -0.300   0.027  -0.016  -0.102  -0.364  -0.411  -0.482
149   Q        -0.336  -0.376  -0.337  -0.185  -0.208  -0.156  -0.572  -0.598  -0.539
150   P         0.662   0.612   0.422   0.831   0.768   0.490   0.675   0.595   0.242
151   M        -0.735  -0.645  -0.764  -0.683  -0.548  -0.713  -0.780  -0.665  -0.785
152   K        -0.517  -0.527  -0.401  -0.807  -0.859  -0.665  -0.780  -0.790  -0.623
153   T        -0.336  -0.398  -0.345  -0.683  -0.776  -0.692  -0.572  -0.636  -0.553
154   A         0.186   0.214   0.266  -0.321  -0.273  -0.185  -0.156  -0.109  -0.056
155   L        -1.495  -1.424  -1.457  -1.302  -1.200  -1.248  -1.196  -1.125  -1.114
156   S         0.133   0.149   0.248  -0.409  -0.387  -0.211  -0.260  -0.237  -0.092
157   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
158   T        -1.205  -1.092  -1.165  -1.377  -1.232  -1.258  -1.092  -0.972  -1.004
159   I        -0.735  -0.718  -0.784  -0.867  -0.829  -0.882  -0.780  -0.780  -0.809
160   A         0.662   0.706   0.435   0.460   0.513   0.157   0.675   0.740   0.267
161   T         0.662   0.565   0.422   0.707   0.582   0.360   0.675   0.519   0.242
162   I        -0.213  -0.189  -0.313  -0.252  -0.222  -0.409  -0.364  -0.335  -0.506
163   A        -0.502  -0.533  -0.733  -0.639  -0.694  -0.972  -0.468  -0.510  -0.743
164   A         0.186   0.244   0.288  -0.262  -0.137  -0.095  -0.156  -0.052  -0.013
165   D         1.292   1.307   1.361   1.448   1.464   1.542   1.403   1.424   1.508
166   A         1.292   1.307   1.361   1.014   1.031   1.134   1.403   1.424   1.508
167   L         0.662   0.565   0.422   0.718   0.600   0.387   0.675   0.519   0.242
168   M         1.292   1.307   1.361   1.414   1.429   1.511   1.403   1.424   1.508
169   N         0.186   0.187   0.260   0.084   0.082   0.172  -0.156  -0.163  -0.067
170   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
171   F         1.292   1.307   1.361   1.359   1.379   1.459   1.403   1.424   1.508
172   D         1.292   1.307   1.361   1.448   1.464   1.542   1.403   1.424   1.508
173   T        -0.213  -0.138  -0.286  -0.174  -0.066  -0.276  -0.364  -0.254  -0.463
174   V        -0.213  -0.122  -0.281  -0.246  -0.113  -0.344  -0.364  -0.237  -0.455
175   K         1.292   1.307   1.361   1.357   1.383   1.457   1.403   1.424   1.508
176   Q         1.292   1.307   1.361   1.438   1.465   1.534   1.403   1.424   1.508
177   R         1.292   1.307   1.361   1.449   1.463   1.544   1.403   1.424   1.508
178   L         0.352   0.409   0.334   0.401   0.491   0.330   0.156   0.252   0.076
179   Q         1.292   1.307   1.361   1.438   1.465   1.534   1.403   1.424   1.508
180   L        -0.213  -0.220  -0.299  -0.363  -0.349  -0.518  -0.364  -0.361  -0.481
181   D        -1.315  -1.258  -1.194  -1.118  -1.035  -0.945  -1.196  -1.143  -1.030
182   T        -0.916  -0.904  -0.816  -1.229  -1.183  -1.050  -0.988  -0.961  -0.843
183   N        -1.604  -1.536  -1.485  -1.475  -1.377  -1.295  -1.300  -1.240  -1.137
184   -        -0.934  -0.900  -0.841  -1.167  -1.114  -0.988  -0.992  -0.950  -0.867
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -0.296  -0.271  -0.322  -0.381  -0.332  -0.411  -0.460  -0.426  -0.510
190   -        -0.934  -0.969  -0.857  -1.154  -1.224  -1.063  -0.992  -1.027  -0.884
191   -        -0.930  -0.919  -0.840  -0.997  -0.952  -0.829  -1.000  -0.980  -0.867
192   L        -1.894  -1.886  -1.759  -1.751  -1.734  -1.579  -1.404  -1.390  -1.233
193   R        -0.735  -0.674  -0.776  -0.739  -0.647  -0.768  -0.780  -0.698  -0.799
194   V        -1.315  -1.334  -1.203  -1.317  -1.362  -1.158  -1.196  -1.199  -1.036
195   W        -0.806  -0.775  -0.798  -0.744  -0.715  -0.770  -0.884  -0.843  -0.824
196   N        -1.604  -1.573  -1.483  -1.158  -1.105  -0.990  -1.300  -1.267  -1.136
197   V        -1.205  -1.194  -1.179  -0.986  -0.961  -0.944  -1.092  -1.083  -1.016
198   T         0.352   0.439   0.354   0.011   0.146   0.017   0.156   0.305   0.115
199   K        -0.735  -0.759  -0.785  -0.698  -0.715  -0.776  -0.780  -0.797  -0.805
200   Q        -1.205  -1.241  -1.178  -0.919  -0.970  -0.878  -1.092  -1.116  -1.013
201   I         0.352   0.274   0.287   0.287   0.146   0.155   0.156   0.005  -0.014
202   Y         0.352   0.297   0.294   0.423   0.322   0.290   0.156   0.048  -0.001
203   Q        -0.735  -0.689  -0.787  -0.510  -0.470  -0.553  -0.780  -0.751  -0.812
204   N        -0.213  -0.120  -0.296  -0.134   0.024  -0.314  -0.364  -0.226  -0.480
205   E         1.292   1.307   1.361   1.397   1.420   1.495   1.403   1.424   1.508
206   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
207   F        -0.336  -0.322  -0.334  -0.405  -0.399  -0.379  -0.572  -0.562  -0.541
208   A        -0.916  -0.837  -0.823  -1.192  -1.030  -1.004  -0.988  -0.891  -0.848
209   A         1.292   1.307   1.361   1.014   1.031   1.134   1.403   1.424   1.508
210   F         1.292   1.307   1.361   1.359   1.379   1.459   1.403   1.424   1.508
211   Y         0.662   0.698   0.430   0.863   0.904   0.531   0.675   0.729   0.257
212   Y        -0.517  -0.513  -0.398  -0.632  -0.641  -0.458  -0.780  -0.772  -0.619
213   S         1.292   1.307   1.361   1.174   1.198   1.285   1.403   1.424   1.508
214   Y         1.292   1.307   1.361   1.404   1.418   1.502   1.403   1.424   1.508
215   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
216   T         1.292   1.307   1.361   1.261   1.282   1.366   1.403   1.424   1.508
217   T         0.662   0.565   0.422   0.744   0.632   0.446   0.675   0.519   0.242
218   L         0.662   0.565   0.422   0.705   0.583   0.358   0.675   0.519   0.242
219   A        -1.025  -0.957  -1.125  -1.144  -1.057  -1.275  -0.884  -0.809  -0.961
220   M         0.352   0.405   0.344   0.402   0.484   0.350   0.156   0.245   0.095
221   N         0.062  -0.082  -0.252   0.292   0.091  -0.221   0.052  -0.153  -0.409
222   I         0.352   0.323   0.297   0.287   0.230   0.172   0.156   0.096   0.005
223   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
224   F         1.292   1.307   1.361   1.359   1.379   1.459   1.403   1.424   1.508
225   A         0.186   0.161   0.249  -0.272  -0.314  -0.149  -0.156  -0.214  -0.090
226   A         1.292   1.307   1.361   1.014   1.031   1.134   1.403   1.424   1.508
227   F        -0.446  -0.428  -0.365  -0.590  -0.568  -0.475  -0.676  -0.655  -0.573
228   N         0.352   0.274   0.287   0.456   0.334   0.324   0.156   0.005  -0.014
229   F         0.662   0.565   0.422   0.813   0.688   0.468   0.675   0.519   0.242
230   M        -1.604  -1.588  -1.492  -1.702  -1.702  -1.509  -1.300  -1.278  -1.142
231   I        -1.205  -1.276  -1.200  -1.214  -1.338  -1.241  -1.092  -1.146  -1.033
232   Y         1.292   1.307   1.361   1.404   1.418   1.502   1.403   1.424   1.508
233   E         0.662   0.565   0.422   0.868   0.753   0.541   0.675   0.519   0.242
234   S        -0.213  -0.258  -0.300  -0.296  -0.350  -0.414  -0.364  -0.411  -0.482
235   A        -0.806  -0.884  -0.811  -1.093  -1.159  -1.007  -0.884  -0.949  -0.839
236   S        -0.213  -0.246  -0.298  -0.323  -0.341  -0.423  -0.364  -0.392  -0.480
237   K        -0.336  -0.373  -0.345  -0.481  -0.530  -0.485  -0.572  -0.611  -0.553
238   F        -1.025  -1.020  -1.147  -0.819  -0.817  -1.061  -0.884  -0.875  -0.982
239   F        -0.446  -0.404  -0.375  -0.528  -0.458  -0.415  -0.676  -0.616  -0.586
240   N         1.292   1.307   1.361   1.412   1.436   1.509   1.403   1.424   1.508
241   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
242   Q        -0.916  -0.895  -0.828  -1.006  -0.969  -0.838  -0.988  -0.970  -0.857
243   N        -1.025  -1.119  -1.159  -0.703  -0.865  -0.938  -0.884  -0.982  -0.994
244   S        -1.205  -1.122  -1.174  -1.170  -1.053  -1.157  -1.092  -1.016  -1.011
245   Y         1.292   1.307   1.361   1.404   1.418   1.502   1.403   1.424   1.508
246   N         0.186   0.161   0.249   0.181   0.133   0.261  -0.156  -0.214  -0.090
247   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
248   L        -1.604  -1.610  -1.495  -1.466  -1.504  -1.319  -1.300  -1.296  -1.145
249   I        -1.205  -1.276  -1.200  -1.244  -1.356  -1.254  -1.092  -1.146  -1.033
250   H         1.292   1.307   1.361   1.481   1.501   1.574   1.403   1.424   1.508
251   C         0.662   0.565   0.422   0.969   0.839   0.597   0.675   0.519   0.242
252   L        -0.517  -0.513  -0.401  -0.719  -0.717  -0.541  -0.780  -0.772  -0.622
253   C        -0.446  -0.432  -0.373  -0.699  -0.698  -0.600  -0.676  -0.658  -0.584
254   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
255   G         0.662   0.612   0.422   0.685   0.609   0.287   0.675   0.595   0.242
256   I        -0.446  -0.474  -0.392  -0.596  -0.652  -0.529  -0.676  -0.717  -0.610
257   S         0.186   0.200   0.265  -0.321  -0.301  -0.187  -0.156  -0.138  -0.058
258   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
259   A         0.186   0.200   0.262  -0.264  -0.248  -0.128  -0.156  -0.137  -0.065
260   T        -0.806  -0.831  -0.815  -0.864  -0.885  -0.829  -0.884  -0.897  -0.842
261   C         0.186   0.244   0.288  -0.120  -0.046   0.053  -0.156  -0.052  -0.013
262   A         0.662   0.565   0.422   0.444   0.312   0.098   0.675   0.519   0.242
263   A         0.662   0.565   0.422   0.444   0.312   0.098   0.675   0.519   0.242
264   L        -0.446  -0.387  -0.368  -0.602  -0.503  -0.490  -0.676  -0.592  -0.577
265   T         1.292   1.307   1.361   1.261   1.282   1.366   1.403   1.424   1.508
266   T         0.662   0.714   0.439   0.727   0.794   0.434   0.675   0.752   0.273
267   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
268   L         0.062   0.044  -0.230   0.196   0.179  -0.201   0.052   0.024  -0.378
269   D         1.292   1.307   1.361   1.448   1.464   1.542   1.403   1.424   1.508
270   C         0.186   0.161   0.249   0.217   0.141   0.266  -0.156  -0.214  -0.090
271   I         0.352   0.297   0.294   0.287   0.186   0.167   0.156   0.048  -0.001
272   K         1.292   1.307   1.361   1.357   1.383   1.457   1.403   1.424   1.508
273   T         1.292   1.307   1.361   1.261   1.282   1.366   1.403   1.424   1.508
274   V        -1.025  -1.114  -1.157  -0.842  -0.983  -1.094  -0.884  -0.977  -0.992
275   L         1.292   1.307   1.361   1.259   1.283   1.364   1.403   1.424   1.508
276   Q         1.292   1.307   1.361   1.438   1.465   1.534   1.403   1.424   1.508
277   V        -0.213  -0.118  -0.288  -0.241  -0.093  -0.352  -0.364  -0.221  -0.464
278   R         0.352   0.405   0.344   0.466   0.545   0.421   0.156   0.245   0.095
279   G         0.662   0.662   0.428   0.746   0.743   0.442   0.675   0.673   0.253
280   S        -0.446  -0.435  -0.374  -0.819  -0.813  -0.738  -0.676  -0.661  -0.586
281   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   V        -0.336  -0.342  -0.335  -0.588  -0.593  -0.596  -0.572  -0.559  -0.536
284   S        -1.205  -1.174  -1.172  -1.049  -1.000  -0.938  -1.092  -1.059  -1.010
285   I        -1.205  -1.232  -1.176  -1.050  -1.094  -1.024  -1.092  -1.112  -1.014
286   E        -1.025  -1.119  -1.159  -0.768  -0.922  -1.032  -0.884  -0.982  -0.994
287   I        -0.916  -0.837  -0.823  -0.898  -0.752  -0.769  -0.988  -0.891  -0.848
288   M        -0.517  -0.478  -0.398  -0.575  -0.527  -0.399  -0.780  -0.725  -0.618
289   K         0.133   0.157   0.252   0.049   0.097   0.238  -0.260  -0.221  -0.083
290   D        -2.183  -2.152  -1.980  -1.886  -1.874  -1.602  -1.508  -1.478  -1.294
291   A        -0.806  -0.857  -0.816  -0.974  -1.004  -0.893  -0.884  -0.923  -0.843
292   N        -0.446  -0.450  -0.376  -0.464  -0.464  -0.383  -0.676  -0.684  -0.588
293   T         0.133   0.153   0.249  -0.148  -0.118   0.042  -0.260  -0.230  -0.089
294   F         0.662   0.565   0.422   0.792   0.661   0.416   0.675   0.519   0.242
295   G        -1.495  -1.512  -1.478  -1.315  -1.361  -1.346  -1.196  -1.209  -1.131
296   R        -1.604  -1.638  -1.508  -1.519  -1.577  -1.389  -1.300  -1.314  -1.154
297   A         0.062  -0.082  -0.252  -0.079  -0.278  -0.507   0.052  -0.153  -0.409
298   S        -1.205  -1.196  -1.176  -1.350  -1.310  -1.244  -1.092  -1.084  -1.013
299   R        -1.205  -1.136  -1.159  -0.977  -0.882  -0.923  -1.092  -1.028  -0.998
300   A        -0.502  -0.640  -0.771  -0.614  -0.806  -0.980  -0.468  -0.637  -0.788
301   I         0.186   0.200   0.262  -0.041  -0.020   0.065  -0.156  -0.137  -0.065
302   L        -0.735  -0.646  -0.774  -0.556  -0.420  -0.600  -0.780  -0.667  -0.797
303   E        -1.205  -1.221  -1.182  -0.924  -0.935  -0.864  -1.092  -1.105  -1.018
304   V        -1.894  -1.871  -1.746  -1.546  -1.498  -1.349  -1.404  -1.380  -1.224
305   H        -1.604  -1.604  -1.493  -1.290  -1.295  -1.154  -1.300  -1.290  -1.143
306   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
307   W        -1.495  -1.543  -1.495  -1.158  -1.256  -1.271  -1.196  -1.234  -1.144
308   K        -0.502  -0.561  -0.735  -0.249  -0.321  -0.602  -0.468  -0.542  -0.745
309   G        -0.213  -0.258  -0.300  -0.367  -0.425  -0.544  -0.364  -0.411  -0.482
310   F         1.292   1.307   1.361   1.359   1.379   1.459   1.403   1.424   1.508
311   W        -0.806  -0.720  -0.797  -0.644  -0.534  -0.639  -0.884  -0.792  -0.825
312   R         0.186   0.167   0.251   0.166   0.117   0.235  -0.156  -0.202  -0.085
313   G         1.292   1.307   1.361   1.274   1.288   1.379   1.403   1.424   1.508
314   L         0.662   0.565   0.422   0.705   0.583   0.358   0.675   0.519   0.242
315   K        -0.213  -0.237  -0.319  -0.074  -0.118  -0.216  -0.364  -0.416  -0.513
316   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
317   R         1.292   1.307   1.361   1.449   1.463   1.544   1.403   1.424   1.508
318   I        -0.336  -0.388  -0.330  -0.411  -0.471  -0.366  -0.572  -0.620  -0.535
319   V        -0.336  -0.375  -0.341  -0.456  -0.513  -0.440  -0.572  -0.615  -0.550
320   A        -1.205  -1.258  -1.185  -1.395  -1.459  -1.334  -1.092  -1.130  -1.019
321   N         0.062  -0.082  -0.252   0.268   0.055  -0.275   0.052  -0.153  -0.409
322   I        -0.336  -0.276  -0.327  -0.360  -0.265  -0.325  -0.572  -0.489  -0.530
323   P         1.292   1.307   1.361   1.372   1.389   1.471   1.403   1.424   1.508
324   A         0.133   0.148   0.247  -0.409  -0.384  -0.207  -0.260  -0.240  -0.093
325   T         1.292   1.307   1.361   1.261   1.282   1.366   1.403   1.424   1.508
326   A         1.292   1.307   1.361   1.014   1.031   1.134   1.403   1.424   1.508
327   I         0.662   0.565   0.422   0.727   0.599   0.390   0.675   0.519   0.242
328   S         0.352   0.323   0.297   0.258   0.219   0.192   0.156   0.096   0.005
329   W         1.292   1.307   1.361   1.538   1.558   1.628   1.403   1.424   1.508
330   T         0.062  -0.082  -0.252   0.100  -0.117  -0.443   0.052  -0.153  -0.409
331   A         0.186   0.222   0.267  -0.321  -0.259  -0.182  -0.156  -0.094  -0.053
332   Y         1.292   1.307   1.361   1.404   1.418   1.502   1.403   1.424   1.508
333   E         1.292   1.307   1.361   1.397   1.420   1.495   1.403   1.424   1.508
334   C        -0.916  -0.889  -0.833  -0.906  -0.927  -0.806  -0.988  -0.958  -0.861
335   A        -0.502  -0.606  -0.744  -0.595  -0.753  -0.907  -0.468  -0.597  -0.757
336   K         1.292   1.307   1.361   1.357   1.383   1.457   1.403   1.424   1.508
337   H        -0.806  -0.831  -0.815  -0.689  -0.728  -0.733  -0.884  -0.897  -0.842
338   F        -1.315  -1.317  -1.200  -1.240  -1.239  -1.069  -1.196  -1.187  -1.034
339   L         0.662   0.612   0.422   0.718   0.662   0.388   0.675   0.595   0.242
340   M        -1.495  -1.380  -1.452  -1.376  -1.209  -1.338  -1.196  -1.083  -1.109
341   -        -1.629  -1.593  -1.491  -1.271  -1.211  -1.090  -1.313  -1.274  -1.141
342   -        -1.316  -1.285  -1.198  -1.153  -1.100  -0.987  -1.184  -1.149  -1.030
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -0.934  -0.910  -0.836  -0.996  -0.962  -0.830  -0.992  -0.960  -0.861
348   K        -0.967  -0.953  -0.846  -1.022  -0.973  -0.826  -1.041  -1.016  -0.874
349   N        -1.298  -1.289  -1.190  -1.426  -1.441  -1.255  -1.177  -1.162  -1.025
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P23500
Output conservation file - output/P23500
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
