1     M         2.167   2.181   2.354   2.363   2.380   2.659   2.499   2.524   2.848
2     T        -0.235  -0.307  -0.304  -0.186  -0.291  -0.297  -0.346  -0.429  -0.414
3     V        -1.135  -1.087  -1.131  -1.178  -1.110  -1.181  -0.887  -0.838  -0.849
4     G        -1.135  -1.172  -1.180  -0.885  -0.942  -0.994  -0.887  -0.925  -0.896
5     I        -0.792  -0.774  -0.778  -0.661  -0.616  -0.620  -0.752  -0.730  -0.703
6     A         0.285   0.276   0.252   0.240   0.220   0.184   0.072   0.054  -0.018
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     R         0.590   0.577   0.387   0.557   0.532   0.199   0.553   0.531   0.205
10    K        -0.902  -0.900  -0.837  -0.859  -0.843  -0.754  -0.862  -0.859  -0.763
11    L         0.590   0.577   0.387   0.487   0.469   0.223   0.553   0.531   0.205
12    S        -0.578  -0.610  -0.739  -0.355  -0.397  -0.639  -0.481  -0.522  -0.650
13    R         1.054   1.079   1.124   0.919   0.952   1.009   0.873   0.919   0.933
14    D        -0.921  -0.955  -0.853  -0.834  -0.873  -0.720  -0.887  -0.913  -0.780
15    K        -0.449  -0.492  -0.390  -0.741  -0.794  -0.646  -0.616  -0.659  -0.526
16    A        -0.792  -0.816  -0.797  -0.739  -0.776  -0.743  -0.752  -0.774  -0.722
17    H         1.421   1.329   1.293   1.706   1.576   1.513   1.551   1.390   1.283
18    R         0.041  -0.014  -0.205   0.104   0.022  -0.291   0.061  -0.018  -0.274
19    D        -0.921  -0.938  -0.861  -0.998  -1.024  -0.901  -0.887  -0.900  -0.786
20    A        -0.235  -0.280  -0.299  -0.208  -0.269  -0.310  -0.346  -0.396  -0.418
21    L        -0.235  -0.275  -0.299  -0.361  -0.416  -0.429  -0.346  -0.392  -0.418
22    L         0.041   0.092  -0.147   0.073   0.147  -0.158   0.061   0.131  -0.195
23    K         0.238   0.185   0.262  -0.127  -0.185  -0.083  -0.075  -0.132  -0.031
24    N         1.421   1.329   1.293   1.599   1.471   1.404   1.551   1.390   1.283
25    L         1.054   1.019   1.044   0.807   0.760   0.778   0.873   0.797   0.760
26    A        -0.449  -0.477  -0.378  -0.368  -0.399  -0.250  -0.616  -0.639  -0.511
27    C         0.384   0.443   0.372   0.418   0.497   0.431   0.196   0.281   0.171
28    Q         0.108   0.153   0.228   0.066   0.145   0.236  -0.210  -0.143  -0.058
29    L         1.421   1.329   1.293   1.305   1.201   1.166   1.551   1.390   1.283
30    F        -0.235  -0.161  -0.275  -0.187  -0.069  -0.256  -0.346  -0.250  -0.382
31    Q        -0.578  -0.567  -0.442  -0.909  -0.897  -0.716  -0.752  -0.740  -0.584
32    H         1.421   1.408   1.312   1.753   1.738   1.635   1.551   1.529   1.320
33    E         1.054   1.093   1.094   0.992   1.050   1.027   0.873   0.946   0.868
34    S         0.108   0.126   0.212   0.074   0.107   0.211  -0.210  -0.185  -0.084
35    I         1.421   1.456   1.321   1.624   1.668   1.508   1.551   1.610   1.339
36    V         0.041   0.067  -0.146   0.319   0.349   0.074   0.061   0.096  -0.192
37    S         0.857   0.894   0.996   0.660   0.730   0.854   0.467   0.538   0.653
38    T         1.421   1.438   1.324   1.544   1.568   1.440   1.551   1.579   1.344
39    H        -1.265  -1.239  -1.209  -0.925  -0.907  -0.823  -1.023  -1.000  -0.926
40    A        -0.792  -0.825  -0.771  -0.821  -0.893  -0.812  -0.752  -0.786  -0.696
41    K         1.421   1.329   1.293   1.318   1.206   1.181   1.551   1.390   1.283
42    C         0.384   0.448   0.343   0.401   0.487   0.327   0.196   0.297   0.117
43    K         1.421   1.456   1.321   1.312   1.355   1.211   1.551   1.610   1.339
44    E         0.384   0.365   0.291   0.294   0.239   0.098   0.196   0.148   0.028
45    A         0.041  -0.010  -0.154   0.203   0.119  -0.087   0.061  -0.013  -0.204
46    S         0.384   0.341   0.337   0.477   0.430   0.396   0.196   0.145   0.108
47    R         0.710   0.645   0.489   0.771   0.673   0.459   0.738   0.633   0.373
48    V        -1.265  -1.266  -1.197  -1.245  -1.270  -1.147  -1.023  -1.024  -0.917
49    A        -0.235  -0.272  -0.295  -0.163  -0.212  -0.224  -0.346  -0.389  -0.402
50    E         1.054   1.018   1.045   0.996   0.935   0.947   0.873   0.795   0.761
51    R         0.238   0.178   0.274  -0.130  -0.208  -0.073  -0.075  -0.146  -0.015
52    I        -0.449  -0.423  -0.370  -0.499  -0.463  -0.393  -0.616  -0.588  -0.501
53    I         0.384   0.321   0.316   0.375   0.291   0.234   0.196   0.111   0.079
54    T        -0.578  -0.609  -0.726  -0.298  -0.339  -0.508  -0.481  -0.520  -0.635
55    W        -1.608  -1.618  -1.550  -1.194  -1.230  -1.142  -1.158  -1.166  -1.062
56    T         0.108   0.141   0.199  -0.075  -0.024   0.039  -0.210  -0.162  -0.104
57    K         0.710   0.744   0.491   0.653   0.694   0.355   0.738   0.790   0.377
58    R        -0.235  -0.183  -0.266  -0.322  -0.247  -0.385  -0.346  -0.279  -0.377
59    A        -0.792  -0.797  -0.795  -0.688  -0.700  -0.674  -0.752  -0.762  -0.722
60    I        -0.449  -0.456  -0.389  -0.380  -0.390  -0.293  -0.616  -0.623  -0.528
61    T        -1.608  -1.603  -1.563  -1.480  -1.480  -1.370  -1.158  -1.155  -1.071
62    T        -0.792  -0.739  -0.770  -0.659  -0.576  -0.619  -0.752  -0.695  -0.695
63    S        -1.608  -1.618  -1.550  -1.344  -1.355  -1.266  -1.158  -1.166  -1.062
64    N        -1.135  -1.171  -1.169  -0.892  -0.948  -0.988  -0.887  -0.924  -0.886
65    S        -1.265  -1.258  -1.230  -1.179  -1.185  -1.103  -1.023  -1.017  -0.943
66    V        -0.902  -0.946  -0.843  -0.889  -0.949  -0.813  -0.862  -0.902  -0.768
67    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
68    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
69    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
71    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
72    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
73    S        -1.294  -1.307  -1.235  -1.237  -1.266  -1.178  -1.039  -1.051  -0.946
74    Q        -1.294  -1.276  -1.224  -1.311  -1.290  -1.193  -1.039  -1.024  -0.936
75    I        -0.921  -0.945  -0.845  -1.015  -1.026  -0.903  -0.887  -0.905  -0.773
76    Q         0.857   0.880   0.990   0.695   0.739   0.873   0.467   0.508   0.640
77    S        -0.792  -0.827  -0.808  -0.637  -0.705  -0.658  -0.752  -0.788  -0.733
78    Q        -1.135  -1.148  -1.163  -1.091  -1.111  -1.113  -0.887  -0.902  -0.880
79    L         1.421   1.454   1.316   1.277   1.325   1.145   1.551   1.606   1.328
80    F        -0.449  -0.491  -0.385  -0.388  -0.442  -0.276  -0.616  -0.658  -0.521
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    L         0.834   0.853   0.983   0.340   0.363   0.546   0.418   0.451   0.624
90    A         0.078   0.090   0.169  -0.083  -0.063   0.035  -0.275  -0.261  -0.156
91    G         0.834   0.853   0.983   0.734   0.767   0.949   0.418   0.451   0.624
92    D         0.041   0.066  -0.146   0.356   0.390   0.078   0.061   0.094  -0.193
93    N        -0.792  -0.837  -0.802  -0.870  -0.956  -0.952  -0.752  -0.796  -0.728
94    R        -1.608  -1.611  -1.547  -1.349  -1.346  -1.265  -1.158  -1.161  -1.059
95    K        -1.265  -1.284  -1.231  -1.260  -1.266  -1.181  -1.023  -1.037  -0.944
96    L        -0.578  -0.610  -0.739  -0.529  -0.569  -0.727  -0.481  -0.522  -0.650
97    M        -0.235  -0.259  -0.287  -0.353  -0.386  -0.398  -0.346  -0.374  -0.391
98    K        -0.235  -0.219  -0.259  -0.424  -0.396  -0.460  -0.346  -0.323  -0.355
99    R         1.421   1.477   1.328   1.269   1.340   1.141   1.551   1.645   1.353
100   L        -0.235  -0.275  -0.310  -0.371  -0.418  -0.443  -0.346  -0.393  -0.429
101   F        -0.578  -0.609  -0.726  -0.133  -0.180  -0.366  -0.481  -0.520  -0.635
102   S        -0.921  -0.894  -0.839  -0.806  -0.776  -0.676  -0.887  -0.863  -0.768
103   E        -0.235  -0.276  -0.307  -0.166  -0.219  -0.259  -0.346  -0.393  -0.418
104   I         0.857   0.847   0.969   0.587   0.554   0.689   0.467   0.437   0.593
105   A        -0.792  -0.837  -0.802  -0.850  -0.947  -0.894  -0.752  -0.796  -0.728
106   P         0.384   0.385   0.353   0.469   0.473   0.420   0.196   0.202   0.140
107   R         2.167   2.181   2.354   2.078   2.090   2.363   2.499   2.524   2.848
108   Y         2.167   2.181   2.354   2.396   2.413   2.694   2.499   2.524   2.848
109   L        -1.608  -1.603  -1.563  -1.415  -1.400  -1.376  -1.158  -1.155  -1.071
110   E        -1.608  -1.618  -1.550  -1.439  -1.448  -1.361  -1.158  -1.166  -1.062
111   R         2.167   2.181   2.354   2.078   2.090   2.363   2.499   2.524   2.848
112   P        -0.449  -0.440  -0.381  -0.476  -0.465  -0.383  -0.616  -0.611  -0.518
113   G         0.384   0.423   0.350   0.596   0.644   0.587   0.196   0.254   0.134
114   G         2.167   2.181   2.354   2.280   2.293   2.573   2.499   2.524   2.848
115   Y         1.054   1.079   1.124   1.253   1.289   1.354   0.873   0.919   0.933
116   T         1.421   1.329   1.293   1.524   1.404   1.353   1.551   1.390   1.283
117   R         2.167   2.181   2.354   2.078   2.090   2.363   2.499   2.524   2.848
118   V         0.041  -0.014  -0.161   0.257   0.176  -0.050   0.061  -0.018  -0.214
119   L         0.108   0.145   0.219  -0.150  -0.094   0.012  -0.210  -0.156  -0.072
120   R         0.857   0.846   0.973   0.357   0.324   0.494   0.467   0.434   0.601
121   L         1.421   1.408   1.312   1.276   1.269   1.136   1.551   1.529   1.320
122   E         1.421   1.454   1.316   1.506   1.548   1.385   1.551   1.606   1.328
123   P         2.167   2.181   2.354   2.253   2.268   2.545   2.499   2.524   2.848
124   R         1.421   1.408   1.312   1.383   1.359   1.214   1.551   1.529   1.320
125   A         0.041   0.083  -0.130   0.007   0.075  -0.237   0.061   0.117  -0.171
126   N         0.041   0.083  -0.130   0.366   0.420   0.125   0.061   0.117  -0.171
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   D         1.421   1.408   1.312   1.639   1.623   1.511   1.551   1.529   1.320
129   S        -0.921  -0.904  -0.847  -1.057  -1.017  -0.912  -0.887  -0.871  -0.774
130   A         2.167   2.181   2.354   2.140   2.151   2.428   2.499   2.524   2.848
131   P         1.421   1.456   1.321   1.577   1.619   1.445   1.551   1.610   1.339
132   Q         0.238   0.236   0.267   0.282   0.289   0.346  -0.075  -0.071  -0.021
133   S         0.238   0.248   0.270   0.121   0.120   0.177  -0.075  -0.071  -0.023
134   V         1.054   1.065   1.077   1.036   1.041   1.042   0.873   0.890   0.832
135   L         0.710   0.645   0.489   0.642   0.558   0.341   0.738   0.633   0.373
136   E         2.167   2.181   2.354   2.157   2.176   2.446   2.499   2.524   2.848
137   L         0.710   0.644   0.483   0.689   0.613   0.418   0.738   0.632   0.363
138   V         2.167   2.181   2.354   2.202   2.209   2.492   2.499   2.524   2.848
139   D         2.167   2.181   2.354   2.293   2.310   2.587   2.499   2.524   2.848
140   S        -0.319  -0.280  -0.306  -0.290  -0.235  -0.262  -0.481  -0.439  -0.433
141   P         0.384   0.358   0.290   0.469   0.418   0.305   0.196   0.142   0.025
142   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
143   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
144   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
145   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
146   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
147   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   G         0.024   0.042   0.169  -0.213  -0.208  -0.020  -0.346  -0.322  -0.157
159   N         0.024   0.035   0.147  -0.113  -0.102   0.063  -0.346  -0.332  -0.189
160   L        -0.449  -0.482  -0.391  -0.462  -0.478  -0.363  -0.616  -0.646  -0.529
161   K         1.054   1.062   1.096   0.719   0.726   0.733   0.873   0.885   0.872
162   M         0.238   0.291   0.286   0.145   0.237   0.226  -0.075  -0.002   0.001
163   W         0.710   0.717   0.504   1.203   1.209   0.929   0.738   0.747   0.397
164   L        -0.319  -0.293  -0.313  -0.327  -0.268  -0.248  -0.481  -0.451  -0.440
165   L         0.238   0.189   0.259  -0.068  -0.113  -0.042  -0.075  -0.125  -0.032
166   V         0.710   0.785   0.520   0.831   0.921   0.566   0.738   0.852   0.424
167   K         0.384   0.335   0.315   0.089  -0.002  -0.058   0.196   0.112   0.063
168   S        -0.578  -0.592  -0.680  -0.348  -0.374  -0.509  -0.481  -0.501  -0.582
169   V         0.710   0.766   0.515   0.941   1.002   0.704   0.738   0.822   0.416
170   I        -0.578  -0.488  -0.695  -0.394  -0.271  -0.575  -0.481  -0.373  -0.599
171   N        -0.578  -0.488  -0.695  -0.412  -0.291  -0.571  -0.481  -0.373  -0.599
172   D        -0.319  -0.283  -0.326  -0.382  -0.345  -0.335  -0.481  -0.443  -0.455
173   D        -0.792  -0.757  -0.787  -0.844  -0.815  -0.854  -0.752  -0.726  -0.714
174   A        -0.921  -0.939  -0.851  -1.112  -1.118  -0.980  -0.887  -0.900  -0.778
175   N         0.041   0.128  -0.149   0.318   0.443   0.022   0.061   0.179  -0.197
176   Q        -0.449  -0.429  -0.389  -0.522  -0.489  -0.464  -0.616  -0.587  -0.527
177   L        -1.135  -1.091  -1.126  -1.240  -1.164  -1.248  -0.887  -0.842  -0.845
178   P        -0.449  -0.430  -0.386  -0.546  -0.523  -0.450  -0.616  -0.599  -0.526
179   H        -0.235  -0.292  -0.277  -0.326  -0.395  -0.365  -0.346  -0.407  -0.383
180   N        -0.449  -0.411  -0.389  -0.430  -0.373  -0.350  -0.616  -0.573  -0.526
181   P         0.238   0.176   0.251   0.221   0.141   0.258  -0.075  -0.150  -0.046
182   L        -0.449  -0.435  -0.369  -0.806  -0.795  -0.694  -0.616  -0.605  -0.506
183   T         2.167   2.181   2.354   2.192   2.212   2.482   2.499   2.524   2.848
184   L        -0.792  -0.729  -0.765  -1.146  -1.038  -1.116  -0.752  -0.681  -0.688
185   Q        -0.921  -0.945  -0.845  -1.146  -1.177  -1.031  -0.887  -0.905  -0.773
186   N         0.710   0.630   0.487   0.995   0.889   0.686   0.738   0.610   0.369
187   L        -0.449  -0.464  -0.391  -0.643  -0.655  -0.523  -0.616  -0.634  -0.531
188   H        -0.792  -0.838  -0.774  -0.765  -0.818  -0.712  -0.752  -0.794  -0.699
189   K         1.421   1.329   1.293   1.299   1.183   1.143   1.551   1.390   1.283
190   V         0.108   0.145   0.219  -0.072  -0.017   0.084  -0.210  -0.156  -0.072
191   A        -0.235  -0.159  -0.276  -0.330  -0.204  -0.431  -0.346  -0.249  -0.385
192   K        -0.792  -0.757  -0.802  -0.841  -0.764  -0.891  -0.752  -0.710  -0.727
193   F         0.041   0.003  -0.154   0.507   0.447   0.249   0.061   0.004  -0.204
194   K         0.384   0.342   0.334   0.185   0.139   0.077   0.196   0.147   0.104
195   A        -1.265  -1.258  -1.230  -1.287  -1.285  -1.226  -1.023  -1.017  -0.943
196   E        -0.792  -0.784  -0.798  -0.724  -0.715  -0.770  -0.752  -0.748  -0.725
197   A         0.041   0.022  -0.161   0.318   0.273  -0.000   0.061   0.030  -0.213
198   Q        -1.265  -1.284  -1.231  -1.137  -1.166  -1.089  -1.023  -1.037  -0.944
199   L        -1.265  -1.240  -1.209  -1.294  -1.237  -1.204  -1.023  -1.000  -0.927
200   H        -1.265  -1.215  -1.201  -1.398  -1.347  -1.309  -1.023  -0.981  -0.920
201   G         0.041   0.128  -0.149   0.468   0.582   0.195   0.061   0.179  -0.197
202   E         0.108   0.143   0.210  -0.082  -0.028   0.056  -0.210  -0.159  -0.087
203   I        -0.792  -0.757  -0.803  -0.730  -0.669  -0.751  -0.752  -0.711  -0.727
204   M        -0.449  -0.412  -0.389  -0.602  -0.547  -0.516  -0.616  -0.574  -0.528
205   L         1.421   1.477   1.328   1.506   1.572   1.368   1.551   1.645   1.353
206   I        -1.265  -1.284  -1.231  -1.194  -1.251  -1.162  -1.023  -1.037  -0.944
207   K        -0.921  -0.955  -0.854  -1.163  -1.198  -1.072  -0.887  -0.913  -0.780
208   Q        -1.951  -1.938  -1.850  -1.709  -1.674  -1.564  -1.294  -1.284  -1.165
209   -         0.285   0.207   0.254  -0.094  -0.223  -0.190   0.072  -0.057  -0.015
210   -        -0.471  -0.412  -0.380  -0.721  -0.604  -0.614  -0.622  -0.549  -0.507
211   -        -0.471  -0.512  -0.424  -0.556  -0.624  -0.489  -0.622  -0.675  -0.562
212   -         0.285   0.274   0.260   0.277   0.256   0.140   0.072   0.051  -0.005
213   -         0.285   0.233   0.264   0.525   0.445   0.493   0.072  -0.017   0.002
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   V        -1.381  -1.374  -1.269  -1.378  -1.374  -1.221  -1.113  -1.106  -0.974
227   L         0.164   0.188   0.214  -0.135  -0.111  -0.029  -0.150  -0.117  -0.094
228   L         0.164   0.161   0.209  -0.392  -0.409  -0.364  -0.150  -0.156  -0.097
229   K         0.449   0.497   0.388   0.417   0.496   0.281   0.332   0.406   0.206
230   E        -0.293  -0.280  -0.291  -0.141  -0.119  -0.163  -0.391  -0.374  -0.391
231   M        -0.466  -0.476  -0.409  -0.546  -0.550  -0.422  -0.632  -0.642  -0.546
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   S        -0.924  -0.951  -0.879  -0.945  -0.989  -0.931  -0.872  -0.901  -0.800
242   L         0.449   0.380   0.354   0.216   0.109   0.039   0.332   0.218   0.150
243   P         2.167   2.181   2.354   2.252   2.267   2.544   2.499   2.524   2.848
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   K        -1.020  -1.006  -0.900  -1.153  -1.140  -0.988  -0.969  -0.955  -0.821
260   E        -0.924  -0.951  -0.879  -0.938  -0.997  -0.923  -0.872  -0.901  -0.800
261   V        -0.924  -0.869  -0.835  -0.909  -0.820  -0.799  -0.872  -0.814  -0.755
262   Y        -0.293  -0.205  -0.288  -0.161  -0.018  -0.169  -0.391  -0.274  -0.387
263   S        -1.381  -1.369  -1.269  -1.198  -1.185  -1.035  -1.113  -1.102  -0.974
264   S        -0.466  -0.443  -0.372  -0.398  -0.371  -0.262  -0.632  -0.606  -0.506
265   S        -0.008   0.002   0.134  -0.181  -0.163   0.023  -0.391  -0.378  -0.207
266   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
267   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
268   L         0.078   0.121   0.195  -0.209  -0.137  -0.037  -0.275  -0.220  -0.121
269   P        -0.924  -0.898  -0.840  -1.142  -1.103  -1.025  -0.872  -0.845  -0.761
270   K        -0.921  -0.898  -0.845  -1.021  -1.008  -0.916  -0.887  -0.866  -0.772
271   K        -0.235  -0.300  -0.286  -0.439  -0.529  -0.513  -0.346  -0.419  -0.398
272   T        -0.792  -0.824  -0.796  -1.088  -1.124  -1.078  -0.752  -0.784  -0.718
273   K        -0.792  -0.837  -0.812  -1.058  -1.103  -1.059  -0.752  -0.796  -0.735
274   K        -1.135  -1.157  -1.138  -0.868  -0.902  -0.877  -0.887  -0.911  -0.857
275   P        -0.792  -0.811  -0.805  -0.734  -0.756  -0.787  -0.752  -0.771  -0.728
276   S         0.041   0.128  -0.149   0.050   0.165  -0.202   0.061   0.179  -0.197
277   S        -1.265  -1.240  -1.196  -1.089  -1.053  -0.999  -1.023  -1.001  -0.917
278   Y         0.108   0.124   0.210   0.328   0.351   0.485  -0.210  -0.188  -0.088
279   V         1.054   1.105   1.107   0.761   0.836   0.811   0.873   0.970   0.896
280   M        -1.265  -1.276  -1.227  -1.026  -1.042  -0.969  -1.023  -1.032  -0.941
281   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
282   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
284   V        -1.294  -1.275  -1.221  -1.140  -1.083  -1.047  -1.039  -1.023  -0.933
285   P         0.590   0.639   0.446   0.758   0.824   0.528   0.553   0.628   0.301
286   R         1.355   1.257   1.254   1.363   1.218   1.227   1.437   1.259   1.205
287   P         2.167   2.181   2.354   2.246   2.261   2.538   2.499   2.524   2.848
288   -        -0.466  -0.488  -0.397  -0.658  -0.697  -0.575  -0.632  -0.654  -0.533
289   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.294  -1.296  -1.212  -0.911  -0.917  -0.780  -1.039  -1.041  -0.926
307   -        -1.687  -1.676  -1.580  -1.682  -1.681  -1.537  -1.216  -1.207  -1.083
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P22353
Output conservation file - output/P22353
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
