1     M         1.606   1.678   1.763   1.741   1.850   1.981   1.756   1.862   2.005
2     M        -0.035  -0.085  -0.171  -0.143  -0.247  -0.338  -0.120  -0.203  -0.320
3     S         0.314   0.351   0.453  -0.004   0.043   0.203  -0.081  -0.038   0.109
4     V        -1.783  -1.702  -1.624  -1.711  -1.475  -1.476  -1.370  -1.271  -1.157
5     N        -1.783  -1.702  -1.624  -1.337  -1.181  -1.101  -1.370  -1.271  -1.157
6     R        -0.307  -0.396  -0.277  -0.542  -0.729  -0.541  -0.536  -0.633  -0.476
7     F        -1.783  -1.702  -1.624  -1.615  -1.480  -1.380  -1.370  -1.271  -1.157
8     T        -0.909  -0.785  -0.804  -0.991  -0.857  -0.838  -0.953  -0.795  -0.785
9     S        -0.914  -0.887  -0.818  -0.928  -0.896  -0.799  -0.945  -0.902  -0.798
10    G        -1.438  -1.367  -1.280  -1.515  -1.442  -1.279  -1.245  -1.150  -1.031
11    R        -0.191  -0.059  -0.178  -0.200  -0.008  -0.194  -0.345  -0.148  -0.330
12    L        -0.914  -0.902  -0.838  -1.148  -1.119  -1.026  -0.945  -0.917  -0.820
13    P        -1.438  -1.367  -1.280  -1.434  -1.325  -1.198  -1.245  -1.150  -1.031
14    V        -1.016  -0.955  -0.858  -1.132  -1.037  -0.897  -1.057  -0.969  -0.841
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    L        -0.914  -0.785  -0.802  -0.974  -0.816  -0.790  -0.945  -0.777  -0.780
29    R        -0.191  -0.088  -0.201  -0.238  -0.082  -0.281  -0.345  -0.193  -0.364
30    K        -0.035   0.169  -0.128  -0.001   0.290  -0.168  -0.120   0.178  -0.258
31    S        -1.346  -1.330  -1.262  -1.327  -1.311  -1.188  -1.162  -1.123  -1.016
32    P        -0.035  -0.121  -0.187  -0.140  -0.296  -0.359  -0.120  -0.261  -0.343
33    F        -1.346  -1.175  -1.225  -1.421  -1.140  -1.244  -1.162  -0.962  -0.981
34    Y        -1.346  -1.300  -1.245  -1.260  -1.201  -1.117  -1.162  -1.097  -1.000
35    Y        -0.909  -0.803  -0.806  -0.984  -0.834  -0.829  -0.953  -0.814  -0.787
36    S        -0.909  -0.776  -0.799  -0.961  -0.765  -0.783  -0.953  -0.791  -0.782
37    R        -0.909  -0.800  -0.806  -0.895  -0.732  -0.752  -0.953  -0.811  -0.787
38    A        -0.307  -0.242  -0.254  -0.374  -0.290  -0.291  -0.536  -0.464  -0.449
39    Y        -1.346  -1.304  -1.245  -1.272  -1.221  -1.135  -1.162  -1.101  -1.000
40    L        -1.346  -1.285  -1.263  -1.256  -1.169  -1.141  -1.162  -1.085  -1.016
41    H        -1.346  -1.285  -1.263  -1.089  -1.014  -0.945  -1.162  -1.085  -1.016
42    Q        -0.909  -0.797  -0.801  -0.803  -0.609  -0.640  -0.953  -0.812  -0.784
43    T        -1.783  -1.702  -1.624  -1.824  -1.709  -1.589  -1.370  -1.271  -1.157
44    C        -1.783  -1.702  -1.624  -1.352  -1.267  -1.117  -1.370  -1.271  -1.157
45    V        -0.035   0.128  -0.121  -0.037   0.200  -0.163  -0.120   0.120  -0.247
46    F        -0.191  -0.245  -0.227  -0.189  -0.311  -0.278  -0.345  -0.431  -0.402
47    K        -0.914  -0.890  -0.839  -1.110  -1.063  -0.981  -0.945  -0.905  -0.821
48    Q        -1.346  -1.314  -1.244  -1.242  -1.238  -1.108  -1.162  -1.109  -1.000
49    N        -1.346  -1.327  -1.264  -1.372  -1.350  -1.244  -1.162  -1.121  -1.017
50    K        -1.346  -1.310  -1.246  -1.489  -1.423  -1.331  -1.162  -1.106  -1.001
51    E        -1.346  -1.314  -1.244  -1.355  -1.292  -1.224  -1.162  -1.109  -1.000
52    T        -1.346  -1.303  -1.244  -1.169  -1.116  -1.017  -1.162  -1.100  -0.999
53    A        -1.783  -1.702  -1.624  -1.631  -1.497  -1.396  -1.370  -1.271  -1.157
54    Q        -0.909  -0.776  -0.799  -0.953  -0.765  -0.781  -0.953  -0.791  -0.782
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -0.360  -0.392  -0.292  -0.541  -0.647  -0.485  -0.589  -0.628  -0.494
58    D        -1.325  -1.247  -1.222  -1.359  -1.235  -1.198  -1.153  -1.051  -0.983
59    S        -1.700  -1.647  -1.610  -1.608  -1.506  -1.480  -1.306  -1.239  -1.147
60    P        -0.809  -0.786  -0.782  -0.813  -0.822  -0.792  -0.847  -0.813  -0.765
61    E        -1.325  -1.319  -1.244  -1.277  -1.241  -1.137  -1.153  -1.118  -1.001
62    L        -1.325  -1.227  -1.233  -1.465  -1.342  -1.304  -1.153  -1.038  -0.991
63    L        -0.809  -0.786  -0.782  -0.979  -0.930  -0.910  -0.847  -0.813  -0.765
64    A        -1.184  -1.210  -1.209  -1.070  -1.123  -1.122  -1.000  -1.017  -0.967
65    K        -2.074  -1.989  -1.916  -1.908  -1.738  -1.673  -1.459  -1.364  -1.247
66    S        -0.576  -0.698  -0.740  -0.486  -0.661  -0.733  -0.541  -0.690  -0.709
67    S        -0.576  -0.702  -0.740  -0.519  -0.702  -0.783  -0.541  -0.695  -0.708
68    H        -1.325  -1.343  -1.257  -1.089  -1.131  -0.965  -1.153  -1.139  -1.012
69    L        -0.435  -0.381  -0.299  -0.840  -0.741  -0.626  -0.694  -0.618  -0.504
70    N        -0.809  -0.794  -0.794  -0.794  -0.789  -0.771  -0.847  -0.809  -0.774
71    S        -1.184  -1.026  -1.156  -1.142  -0.902  -1.133  -1.000  -0.813  -0.915
72    K        -1.184  -1.039  -1.161  -1.024  -0.811  -0.988  -1.000  -0.827  -0.920
73    P        -0.576  -0.486  -0.683  -0.359  -0.247  -0.538  -0.541  -0.418  -0.642
74    L        -1.700  -1.647  -1.610  -1.644  -1.539  -1.542  -1.306  -1.239  -1.147
75    D        -1.346  -1.352  -1.262  -1.039  -1.046  -0.893  -1.162  -1.143  -1.016
76    V        -0.909  -0.814  -0.806  -1.032  -0.868  -0.877  -0.953  -0.825  -0.787
77    S        -1.325  -1.283  -1.240  -1.263  -1.213  -1.125  -1.153  -1.093  -0.998
78    N        -1.700  -1.533  -1.573  -1.689  -1.478  -1.491  -1.306  -1.132  -1.118
79    K         0.830   0.996   0.676   0.796   1.030   0.577   0.837   1.090   0.539
80    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    N        -1.016  -0.967  -0.858  -1.097  -1.032  -0.862  -1.057  -0.982  -0.841
88    K        -0.576  -0.438  -0.686  -0.515  -0.305  -0.676  -0.541  -0.360  -0.646
89    I        -1.325  -1.175  -1.222  -1.202  -1.008  -1.036  -1.153  -0.995  -0.983
90    P        -0.576  -0.567  -0.723  -0.411  -0.442  -0.691  -0.541  -0.541  -0.689
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    L         0.100   0.129  -0.086   0.014   0.058  -0.253   0.072   0.116  -0.197
93    A        -0.809  -0.903  -0.793  -0.870  -0.977  -0.819  -0.847  -0.915  -0.773
94    H        -1.325  -1.366  -1.244  -1.177  -1.225  -1.068  -1.153  -1.155  -1.001
95    S        -1.184  -1.266  -1.236  -1.033  -1.151  -1.084  -1.000  -1.066  -0.992
96    K         0.474   0.506   0.513   0.246   0.300   0.263   0.225   0.261   0.228
97    Y         0.659   0.689   0.599   0.720   0.768   0.615   0.555   0.593   0.394
98    E         0.659   0.508   0.571   0.624   0.390   0.478   0.555   0.266   0.341
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   S         0.314   0.353   0.454   0.061   0.109   0.253  -0.081  -0.034   0.110
101   S        -0.951  -0.850  -0.822  -1.088  -0.922  -0.887  -1.000  -0.879  -0.807
102   K        -0.293  -0.205  -0.224  -0.535  -0.401  -0.398  -0.541  -0.423  -0.412
103   Y        -1.184  -1.266  -1.236  -0.929  -1.070  -1.007  -1.000  -1.066  -0.992
104   E        -0.809  -0.917  -0.789  -0.784  -0.911  -0.740  -0.847  -0.931  -0.771
105   L         0.100   0.129  -0.086   0.067   0.103  -0.160   0.072   0.116  -0.197
106   P        -0.035  -0.111  -0.191   0.126   0.011  -0.130  -0.120  -0.228  -0.350
107   K        -0.744  -0.804  -0.809  -0.732  -0.807  -0.805  -0.745  -0.800  -0.787
108   W         0.830   0.636   0.636   1.134   0.864   0.848   0.837   0.500   0.465
109   K         0.830   0.636   0.636   0.807   0.557   0.536   0.837   0.500   0.465
110   E         0.474   0.514   0.515   0.314   0.377   0.349   0.225   0.277   0.232
111   A        -0.202  -0.127  -0.215  -0.305  -0.206  -0.332  -0.388  -0.290  -0.395
112   L        -0.809  -0.925  -0.815  -0.931  -1.074  -0.896  -0.847  -0.940  -0.797
113   G         1.606   1.678   1.763   1.674   1.783   1.914   1.756   1.862   2.005
114   E         0.402   0.456   0.488   0.180   0.255   0.291   0.089   0.167   0.179
115   L        -0.744  -0.771  -0.780  -0.610  -0.645  -0.674  -0.745  -0.763  -0.755
116   V         0.402   0.396   0.468   0.267   0.236   0.348   0.089   0.051   0.140
117   I         0.402   0.505   0.502   0.267   0.423   0.405   0.089   0.260   0.206
118   R        -0.307  -0.224  -0.239  -0.524  -0.380  -0.431  -0.536  -0.405  -0.423
119   A        -0.744  -0.771  -0.780  -0.693  -0.772  -0.810  -0.745  -0.763  -0.755
120   F         0.754   0.874   0.616   0.791   0.968   0.533   0.714   0.902   0.427
121   H        -0.909  -0.852  -0.812  -0.875  -0.776  -0.702  -0.953  -0.870  -0.795
122   L        -0.307  -0.297  -0.272  -0.541  -0.519  -0.456  -0.536  -0.521  -0.471
123   D         0.754   0.659   0.604   0.854   0.725   0.632   0.714   0.540   0.404
124   M         1.606   1.678   1.763   1.740   1.845   1.979   1.756   1.862   2.005
125   D         1.606   1.678   1.763   1.627   1.732   1.866   1.756   1.862   2.005
126   R         0.402   0.479   0.483   0.125   0.247   0.224   0.089   0.211   0.168
127   V        -0.307  -0.360  -0.277  -0.469  -0.546  -0.426  -0.536  -0.589  -0.476
128   R         1.606   1.678   1.763   1.583   1.685   1.823   1.756   1.862   2.005
129   A         0.754   0.806   0.614   0.744   0.817   0.509   0.714   0.792   0.423
130   G         0.754   0.659   0.604   0.876   0.734   0.624   0.714   0.540   0.404
131   P         1.606   1.678   1.763   1.665   1.767   1.904   1.756   1.862   2.005
132   V         0.754   0.874   0.616   0.799   0.964   0.600   0.714   0.902   0.427
133   A         0.830   0.636   0.636   0.878   0.611   0.608   0.837   0.500   0.465
134   G         0.830   0.636   0.636   0.979   0.702   0.684   0.837   0.500   0.465
135   S        -0.202  -0.350  -0.236  -0.288  -0.502  -0.332  -0.388  -0.569  -0.423
136   Y         0.100   0.243  -0.112   0.270   0.479  -0.051   0.072   0.281  -0.235
137   Y         0.830   0.636   0.636   0.971   0.723   0.715   0.837   0.500   0.465
138   Y         0.474   0.584   0.538   0.421   0.598   0.491   0.225   0.407   0.277
139   K        -1.325  -1.296  -1.234  -1.261  -1.206  -1.118  -1.153  -1.103  -0.993
140   I        -0.435  -0.327  -0.289  -0.737  -0.573  -0.532  -0.694  -0.537  -0.490
141   C         0.830   0.636   0.636   1.161   0.877   0.857   0.837   0.500   0.465
142   K         0.830   0.636   0.636   0.793   0.531   0.506   0.837   0.500   0.465
143   E        -0.809  -0.694  -0.772  -0.870  -0.682  -0.800  -0.847  -0.684  -0.750
144   Q         1.606   1.678   1.763   1.621   1.726   1.861   1.756   1.862   2.005
145   G         0.314   0.351   0.453   0.124   0.150   0.310  -0.081  -0.038   0.109
146   L         0.100  -0.021  -0.142   0.063  -0.117  -0.245   0.072  -0.115  -0.278
147   Q        -0.307  -0.289  -0.272  -0.345  -0.337  -0.272  -0.536  -0.513  -0.471
148   Y         0.754   0.659   0.604   0.853   0.724   0.619   0.714   0.540   0.404
149   E        -0.293  -0.275  -0.241  -0.470  -0.420  -0.386  -0.541  -0.485  -0.431
150   D        -0.809  -0.925  -0.815  -0.724  -0.898  -0.728  -0.847  -0.940  -0.797
151   E         0.100  -0.140  -0.151   0.143  -0.209  -0.245   0.072  -0.270  -0.292
152   P         0.100   0.016  -0.140   0.304   0.162  -0.062   0.072  -0.069  -0.275
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
163   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
164   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
165   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
168   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
169   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
170   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
171   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   L         0.100  -0.037  -0.139   0.034  -0.183  -0.297   0.072  -0.136  -0.274
175   S         0.830   0.636   0.636   0.787   0.495   0.462   0.837   0.500   0.465
176   E        -0.576  -0.614  -0.720  -0.488  -0.535  -0.706  -0.541  -0.593  -0.686
177   T         0.830   0.636   0.636   0.955   0.673   0.661   0.837   0.500   0.465
178   A         0.830   0.636   0.636   0.872   0.599   0.593   0.837   0.500   0.465
179   K         0.830   0.636   0.636   0.787   0.523   0.491   0.837   0.500   0.465
180   Y         0.830   0.999   0.683   0.929   1.147   0.730   0.837   1.095   0.552
181   F        -0.435  -0.401  -0.305  -0.456  -0.369  -0.238  -0.694  -0.641  -0.513
182   Y         1.606   1.678   1.763   1.636   1.747   1.875   1.756   1.862   2.005
183   E         0.830   0.636   0.636   0.834   0.575   0.559   0.837   0.500   0.465
184   D        -0.951  -0.977  -0.835  -1.041  -1.085  -0.876  -1.000  -0.992  -0.819
185   L         0.830   0.636   0.636   0.741   0.504   0.525   0.837   0.500   0.465
186   K        -1.325  -1.319  -1.244  -1.281  -1.266  -1.145  -1.153  -1.118  -1.001
187   L         0.100  -0.140  -0.151   0.066  -0.265  -0.254   0.072  -0.270  -0.292
188   P         1.606   1.678   1.763   1.667   1.758   1.907   1.756   1.862   2.005
189   R        -0.951  -0.836  -0.823  -1.001  -0.773  -0.788  -1.000  -0.852  -0.807
190   T         0.474   0.584   0.538   0.397   0.576   0.456   0.225   0.407   0.277
191   F         1.606   1.678   1.763   1.612   1.710   1.851   1.756   1.862   2.005
192   S        -0.202  -0.345  -0.237  -0.330  -0.533  -0.386  -0.388  -0.563  -0.425
193   Q         0.100  -0.140  -0.151   0.236  -0.135  -0.168   0.072  -0.270  -0.292
194   W         0.100   0.243  -0.112   0.495   0.695   0.198   0.072   0.281  -0.235
195   F         0.100   0.281  -0.083   0.253   0.497  -0.014   0.072   0.333  -0.192
196   Q         1.606   1.678   1.763   1.621   1.726   1.861   1.756   1.862   2.005
197   I         1.606   1.678   1.763   1.662   1.755   1.902   1.756   1.862   2.005
198   T         0.830   0.807   0.685   0.958   0.934   0.750   0.837   0.793   0.554
199   V        -0.809  -0.841  -0.790  -0.783  -0.831  -0.744  -0.847  -0.858  -0.772
200   L         1.606   1.678   1.763   1.383   1.483   1.622   1.756   1.862   2.005
201   H         1.606   1.678   1.763   1.807   1.915   2.047   1.756   1.862   2.005
202   E        -0.202  -0.303  -0.236  -0.341  -0.510  -0.425  -0.388  -0.500  -0.419
203   W         1.606   1.678   1.763   1.818   1.925   2.058   1.756   1.862   2.005
204   I         0.474   0.533   0.517   0.495   0.571   0.542   0.225   0.312   0.237
205   L         1.606   1.678   1.763   1.383   1.483   1.622   1.756   1.862   2.005
206   F        -0.202  -0.303  -0.236  -0.216  -0.322  -0.246  -0.388  -0.500  -0.419
207   V         0.830   0.636   0.636   0.898   0.634   0.626   0.837   0.500   0.465
208   R         1.606   1.678   1.763   1.570   1.664   1.810   1.756   1.862   2.005
209   M         0.830   0.636   0.636   1.062   0.794   0.785   0.837   0.500   0.465
210   R         1.606   1.678   1.763   1.570   1.664   1.810   1.756   1.862   2.005
211   A         0.830   0.636   0.636   0.882   0.620   0.617   0.837   0.500   0.465
212   M         0.314   0.351   0.453   0.075   0.061   0.230  -0.081  -0.038   0.109
213   P         1.606   1.678   1.763   1.667   1.758   1.907   1.756   1.862   2.005
214   F         0.100  -0.140  -0.151   0.242  -0.131  -0.148   0.072  -0.270  -0.292
215   K        -0.576  -0.700  -0.739  -0.502  -0.679  -0.736  -0.541  -0.693  -0.708
216   Y         0.100  -0.140  -0.151   0.254  -0.107  -0.149   0.072  -0.270  -0.292
217   G        -0.576  -0.743  -0.743  -0.395  -0.681  -0.707  -0.541  -0.738  -0.713
218   R        -0.809  -0.918  -0.789  -0.881  -1.030  -0.847  -0.847  -0.933  -0.771
219   N        -0.202  -0.350  -0.236  -0.208  -0.453  -0.298  -0.388  -0.569  -0.423
220   Y         0.830   0.636   0.636   0.949   0.682   0.667   0.837   0.500   0.465
221   Q         0.830   0.636   0.636   0.918   0.637   0.616   0.837   0.500   0.465
222   Q         1.606   1.678   1.763   1.621   1.726   1.861   1.756   1.862   2.005
223   K         0.100  -0.140  -0.151   0.076  -0.283  -0.345   0.072  -0.270  -0.292
224   L         1.606   1.678   1.763   1.383   1.483   1.622   1.756   1.862   2.005
225   V         0.830   0.636   0.636   0.898   0.634   0.626   0.837   0.500   0.465
226   D         0.830   0.636   0.636   0.953   0.689   0.679   0.837   0.500   0.465
227   R         0.830   0.807   0.685   0.875   0.841   0.666   0.837   0.793   0.554
228   T        -0.809  -0.925  -0.815  -0.677  -0.843  -0.660  -0.847  -0.940  -0.797
229   F         1.606   1.678   1.763   1.612   1.710   1.851   1.756   1.862   2.005
230   S        -1.700  -1.686  -1.610  -1.623  -1.609  -1.484  -1.306  -1.265  -1.147
231   D         1.606   1.678   1.763   1.633   1.742   1.873   1.756   1.862   2.005
232   I        -0.202  -0.198  -0.240  -0.162  -0.182  -0.247  -0.388  -0.402  -0.431
233   E         0.830   0.933   0.679   0.836   0.989   0.633   0.837   0.994   0.544
234   L        -0.809  -0.676  -0.756  -1.038  -0.848  -0.938  -0.847  -0.683  -0.735
235   R         1.606   1.678   1.763   1.570   1.664   1.810   1.756   1.862   2.005
236   L        -0.202  -0.303  -0.236  -0.350  -0.484  -0.361  -0.388  -0.500  -0.419
237   F        -1.325  -1.292  -1.241  -1.229  -1.140  -1.079  -1.153  -1.097  -0.999
238   E        -0.809  -0.850  -0.788  -0.854  -0.929  -0.812  -0.847  -0.879  -0.770
239   E         0.830   0.636   0.636   0.836   0.579   0.564   0.837   0.500   0.465
240   M        -0.809  -0.925  -0.815  -0.765  -0.931  -0.777  -0.847  -0.940  -0.797
241   K        -0.951  -0.842  -0.823  -1.023  -0.860  -0.823  -1.000  -0.856  -0.807
242   V         0.314   0.444   0.487   0.126   0.346   0.394  -0.081   0.144   0.176
243   N        -0.576  -0.489  -0.683  -0.359  -0.250  -0.545  -0.541  -0.420  -0.641
244   S         1.606   1.678   1.763   1.511   1.624   1.750   1.756   1.862   2.005
245   G         0.314   0.444   0.487   0.198   0.415   0.464  -0.081   0.144   0.176
246   R         1.606   1.678   1.763   1.570   1.664   1.810   1.756   1.862   2.005
247   I         0.830   0.933   0.679   0.982   1.113   0.777   0.837   0.994   0.544
248   A        -0.809  -0.796  -0.794  -0.775  -0.775  -0.752  -0.847  -0.810  -0.774
249   D        -0.809  -0.925  -0.815  -0.784  -0.924  -0.777  -0.847  -0.940  -0.797
250   Q        -0.809  -0.925  -0.815  -0.675  -0.805  -0.645  -0.847  -0.940  -0.797
251   Y         1.606   1.678   1.763   1.636   1.747   1.875   1.756   1.862   2.005
252   L         0.474   0.534   0.521   0.233   0.317   0.303   0.225   0.315   0.243
253   K         1.606   1.678   1.763   1.489   1.607   1.728   1.756   1.862   2.005
254   D         1.606   1.678   1.763   1.633   1.742   1.873   1.756   1.862   2.005
255   F         0.100  -0.037  -0.139   0.215  -0.033  -0.178   0.072  -0.136  -0.274
256   N        -0.202  -0.303  -0.236  -0.068  -0.219  -0.113  -0.388  -0.500  -0.419
257   T        -1.184  -1.210  -1.209  -1.061  -1.137  -1.156  -1.000  -1.017  -0.967
258   Q         1.606   1.678   1.763   1.621   1.726   1.861   1.756   1.862   2.005
259   L         0.830   0.636   0.636   0.699   0.429   0.430   0.837   0.500   0.465
260   R        -0.202  -0.303  -0.236  -0.348  -0.490  -0.414  -0.388  -0.500  -0.419
261   G         1.606   1.678   1.763   1.674   1.783   1.914   1.756   1.862   2.005
262   A         0.100   0.243  -0.112   0.232   0.431  -0.052   0.072   0.281  -0.235
263   I        -0.202  -0.278  -0.234  -0.194  -0.310  -0.223  -0.388  -0.489  -0.423
264   F         0.314   0.368   0.463  -0.035   0.035   0.176  -0.081  -0.003   0.128
265   A        -0.293  -0.377  -0.256  -0.486  -0.566  -0.394  -0.541  -0.611  -0.452
266   Y         1.606   1.678   1.763   1.636   1.747   1.875   1.756   1.862   2.005
267   D         1.606   1.678   1.763   1.633   1.742   1.873   1.756   1.862   2.005
268   E         0.830   0.636   0.636   0.834   0.575   0.559   0.837   0.500   0.465
269   G         1.606   1.678   1.763   1.674   1.783   1.914   1.756   1.862   2.005
270   F        -0.293  -0.377  -0.256  -0.521  -0.613  -0.424  -0.541  -0.611  -0.452
271   A        -1.325  -1.343  -1.257  -1.208  -1.291  -1.128  -1.153  -1.139  -1.012
272   T        -0.576  -0.702  -0.740  -0.390  -0.589  -0.674  -0.541  -0.695  -0.708
273   D        -0.202  -0.335  -0.233  -0.190  -0.396  -0.255  -0.388  -0.547  -0.420
274   D         1.606   1.678   1.763   1.633   1.742   1.873   1.756   1.862   2.005
275   G        -0.202  -0.025  -0.189  -0.227   0.018  -0.189  -0.388  -0.138  -0.351
276   T        -0.202  -0.178  -0.234  -0.208  -0.238  -0.287  -0.388  -0.396  -0.423
277   L         1.606   1.678   1.763   1.383   1.483   1.622   1.756   1.862   2.005
278   A         1.606   1.678   1.763   1.558   1.661   1.797   1.756   1.862   2.005
279   T        -0.809  -0.786  -0.783  -0.882  -0.838  -0.838  -0.847  -0.813  -0.766
280   A         0.830   0.636   0.636   0.855   0.573   0.555   0.837   0.500   0.465
281   V        -0.435  -0.374  -0.299  -0.741  -0.669  -0.529  -0.694  -0.608  -0.505
282   W         1.606   1.678   1.763   1.818   1.925   2.058   1.756   1.862   2.005
283   R         1.606   1.678   1.763   1.570   1.664   1.810   1.756   1.862   2.005
284   N         1.606   1.678   1.763   1.679   1.781   1.919   1.756   1.862   2.005
285   L         0.474   0.584   0.538   0.167   0.334   0.245   0.225   0.407   0.277
286   F         0.830   0.996   0.676   0.929   1.144   0.719   0.837   1.090   0.539
287   G        -1.325  -1.344  -1.256  -1.155  -1.191  -1.057  -1.153  -1.139  -1.011
288   G         0.830   0.933   0.679   0.979   1.127   0.757   0.837   0.994   0.544
289   R        -0.951  -0.922  -0.827  -1.035  -0.975  -0.836  -1.000  -0.937  -0.810
290   K        -0.202  -0.028  -0.168  -0.241   0.047  -0.198  -0.388  -0.122  -0.322
291   N         0.830   0.636   0.636   0.996   0.724   0.716   0.837   0.500   0.465
292   I        -0.202  -0.012  -0.165  -0.236   0.054  -0.176  -0.388  -0.102  -0.318
293   D         1.606   1.678   1.763   1.633   1.742   1.873   1.756   1.862   2.005
294   M        -0.576  -0.700  -0.739  -0.314  -0.574  -0.616  -0.541  -0.693  -0.708
295   V        -0.809  -0.730  -0.771  -0.837  -0.721  -0.768  -0.847  -0.734  -0.748
296   H         0.830   0.636   0.636   1.127   0.857   0.846   0.837   0.500   0.465
297   L        -0.202  -0.136  -0.216  -0.409  -0.327  -0.411  -0.388  -0.297  -0.395
298   E         0.830   0.807   0.685   0.812   0.799   0.593   0.837   0.793   0.554
299   S        -1.184  -1.206  -1.209  -1.103  -1.140  -1.167  -1.000  -1.014  -0.967
300   V        -0.809  -0.843  -0.789  -0.928  -0.975  -0.843  -0.847  -0.869  -0.771
301   V         0.474   0.584   0.538   0.280   0.463   0.327   0.225   0.407   0.277
302   R        -1.325  -1.263  -1.230  -1.353  -1.242  -1.203  -1.153  -1.062  -0.989
303   Y         0.830   0.636   0.636   0.949   0.682   0.667   0.837   0.500   0.465
304   I         0.474   0.439   0.481   0.385   0.307   0.361   0.225   0.135   0.164
305   Y         0.830   0.999   0.683   0.888   1.101   0.690   0.837   1.095   0.552
306   S        -0.809  -0.842  -0.788  -0.931  -1.029  -0.902  -0.847  -0.869  -0.771
307   Q         0.830   0.636   0.636   0.946   0.682   0.678   0.837   0.500   0.465
308   L         0.830   0.636   0.636   0.691   0.416   0.412   0.837   0.500   0.465
309   Y         1.606   1.678   1.763   1.636   1.747   1.875   1.756   1.862   2.005
310   V         0.100  -0.140  -0.151   0.168  -0.208  -0.258   0.072  -0.270  -0.292
311   L         0.830   0.807   0.685   0.697   0.671   0.503   0.837   0.793   0.554
312   S        -0.202  -0.180  -0.204  -0.297  -0.246  -0.302  -0.388  -0.333  -0.374
313   R        -0.576  -0.563  -0.725  -0.453  -0.408  -0.637  -0.541  -0.536  -0.691
314   L        -0.202  -0.180  -0.204  -0.353  -0.313  -0.327  -0.388  -0.333  -0.374
315   S         0.830   0.933   0.679   0.832   0.983   0.632   0.837   0.994   0.544
316   D         0.830   0.636   0.636   0.953   0.689   0.679   0.837   0.500   0.465
317   R         0.830   0.636   0.636   0.887   0.610   0.613   0.837   0.500   0.465
318   E        -0.202  -0.219  -0.235  -0.303  -0.346  -0.356  -0.388  -0.438  -0.425
319   F         1.606   1.678   1.763   1.612   1.710   1.851   1.756   1.862   2.005
320   A        -0.202  -0.303  -0.236  -0.224  -0.360  -0.260  -0.388  -0.500  -0.419
321   T        -1.325  -1.343  -1.257  -1.111  -1.142  -1.002  -1.153  -1.139  -1.012
322   G         1.606   1.678   1.763   1.674   1.783   1.914   1.756   1.862   2.005
323   K        -1.184  -1.031  -1.159  -1.039  -0.794  -0.983  -1.000  -0.818  -0.918
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   F         0.100  -0.140  -0.151   0.228  -0.138  -0.174   0.072  -0.270  -0.292
326   K         0.100  -0.140  -0.151   0.181  -0.115  -0.138   0.072  -0.270  -0.292
327   F         1.606   1.678   1.763   1.612   1.710   1.851   1.756   1.862   2.005
328   V         0.830   0.807   0.685   0.900   0.881   0.709   0.837   0.793   0.554
329   P        -0.576  -0.471  -0.678  -0.367  -0.222  -0.542  -0.541  -0.400  -0.635
330   P         1.606   1.678   1.763   1.667   1.758   1.907   1.756   1.862   2.005
331   G        -1.184  -1.206  -1.209  -0.892  -0.955  -0.916  -1.000  -1.014  -0.967
332   V        -0.576  -0.484  -0.682  -0.510  -0.370  -0.679  -0.541  -0.415  -0.641
333   K        -1.325  -1.224  -1.230  -1.368  -1.218  -1.225  -1.153  -1.035  -0.988
334   V         0.100  -0.140  -0.151   0.215  -0.139  -0.164   0.072  -0.270  -0.292
335   E         0.100  -0.021  -0.142   0.140  -0.031  -0.234   0.072  -0.115  -0.278
336   K        -0.307  -0.183  -0.257  -0.400  -0.194  -0.318  -0.536  -0.356  -0.448
337   L         0.754   0.806   0.614   0.619   0.693   0.426   0.714   0.792   0.423
338   T         0.754   0.806   0.614   0.850   0.935   0.611   0.714   0.792   0.423
339   P        -0.307  -0.297  -0.272  -0.481  -0.500  -0.490  -0.536  -0.521  -0.471
340   K        -0.035   0.058  -0.169  -0.085   0.054  -0.327  -0.120   0.021  -0.317
341   Q         1.606   1.678   1.763   1.619   1.725   1.858   1.756   1.862   2.005
342   E         1.606   1.678   1.763   1.509   1.610   1.748   1.756   1.862   2.005
343   E        -0.744  -0.717  -0.779  -0.795  -0.770  -0.877  -0.745  -0.703  -0.754
344   E        -0.307  -0.202  -0.243  -0.627  -0.460  -0.546  -0.536  -0.386  -0.433
345   L        -0.744  -0.762  -0.780  -0.787  -0.804  -0.807  -0.745  -0.754  -0.755
346   K        -0.035  -0.111  -0.191  -0.031  -0.119  -0.242  -0.120  -0.228  -0.350
347   A        -0.909  -0.931  -0.824  -1.038  -1.070  -0.896  -0.953  -0.948  -0.807
348   K        -0.035  -0.111  -0.191  -0.111  -0.244  -0.379  -0.120  -0.228  -0.350
349   T        -0.909  -0.925  -0.821  -0.967  -0.996  -0.840  -0.953  -0.943  -0.804
350   I        -0.909  -0.903  -0.835  -1.017  -1.024  -0.912  -0.953  -0.922  -0.818
351   A        -0.307  -0.227  -0.241  -0.486  -0.364  -0.368  -0.536  -0.412  -0.426
352   K        -0.307  -0.360  -0.277  -0.575  -0.651  -0.527  -0.536  -0.589  -0.476
353   Y        -0.307  -0.360  -0.277  -0.365  -0.444  -0.329  -0.536  -0.589  -0.476
354   E        -0.307  -0.360  -0.277  -0.504  -0.585  -0.452  -0.536  -0.589  -0.476
355   A        -0.307  -0.227  -0.241  -0.521  -0.392  -0.400  -0.536  -0.412  -0.426
356   L        -1.346  -1.325  -1.245  -1.330  -1.315  -1.222  -1.162  -1.116  -1.000
357   D         0.542   0.448   0.508   0.488   0.290   0.363   0.349   0.151   0.218
358   K         0.542   0.664   0.536   0.342   0.536   0.290   0.349   0.549   0.273
359   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   T        -0.191  -0.104  -0.227  -0.146  -0.009  -0.236  -0.345  -0.212  -0.402
363   L         1.606   1.678   1.763   1.393   1.493   1.632   1.756   1.862   2.005
364   P         1.606   1.678   1.763   1.670   1.774   1.910   1.756   1.862   2.005
365   S         0.754   0.659   0.604   0.707   0.572   0.454   0.714   0.540   0.404
366   E        -0.909  -0.898  -0.835  -0.952  -0.922  -0.819  -0.953  -0.918  -0.817
367   R        -0.909  -0.909  -0.836  -1.035  -1.025  -0.918  -0.953  -0.928  -0.819
368   S         0.754   0.659   0.604   0.715   0.582   0.472   0.714   0.540   0.404
369   R        -1.346  -1.297  -1.263  -1.329  -1.268  -1.215  -1.162  -1.090  -1.016
370   L        -0.035  -0.067  -0.186  -0.184  -0.253  -0.434  -0.120  -0.169  -0.342
371   S         1.606   1.678   1.763   1.514   1.627   1.754   1.756   1.862   2.005
372   Y        -1.184  -1.266  -1.236  -1.015  -1.148  -1.132  -1.000  -1.066  -0.992
373   T        -0.809  -0.925  -0.815  -0.770  -0.943  -0.796  -0.847  -0.940  -0.797
374   N        -0.809  -0.925  -0.815  -0.749  -0.910  -0.751  -0.847  -0.940  -0.797
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P21560
Output conservation file - output/P21560
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
