1     M         2.049   2.072   2.220   2.268   2.303   2.532   2.290   2.328   2.583
2     S         1.348   1.420   1.249   1.447   1.539   1.329   1.414   1.533   1.198
3     R         1.348   1.313   1.236   1.260   1.208   1.116   1.414   1.354   1.173
4     N         1.348   1.313   1.236   1.447   1.414   1.309   1.414   1.354   1.173
5     V        -0.408  -0.380  -0.349  -0.482  -0.451  -0.397  -0.587  -0.555  -0.500
6     D        -0.207  -0.236  -0.259  -0.344  -0.392  -0.404  -0.337  -0.379  -0.388
7     K         1.348   1.313   1.236   1.287   1.250   1.151   1.414   1.354   1.173
8     A         0.052  -0.020  -0.131   0.288   0.185   0.025   0.038  -0.060  -0.206
9     N         0.115   0.146   0.194   0.003   0.055   0.105  -0.212  -0.167  -0.123
10    S         1.348   1.270   1.239   1.465   1.374   1.350   1.414   1.280   1.179
11    V        -0.408  -0.407  -0.350  -0.375  -0.380  -0.298  -0.587  -0.577  -0.500
12    L         2.049   2.072   2.220   1.910   1.952   2.162   2.290   2.328   2.583
13    V        -0.834  -0.842  -0.784  -0.653  -0.667  -0.550  -0.815  -0.819  -0.730
14    R         1.286   1.200   1.196   1.147   1.014   0.999   1.309   1.155   1.095
15    F         0.936   0.913   0.982   1.025   0.979   1.063   0.656   0.600   0.653
16    Q         0.568   0.584   0.421   0.668   0.685   0.437   0.492   0.517   0.240
17    E         0.271   0.301   0.265   0.040   0.071   0.024   0.002   0.041  -0.028
18    Q        -0.834  -0.862  -0.774  -0.823  -0.839  -0.715  -0.815  -0.838  -0.720
19    Q         0.936   0.910   0.970   0.765   0.701   0.743   0.656   0.593   0.628
20    A         0.568   0.577   0.406   0.716   0.732   0.468   0.492   0.506   0.216
21    E        -0.834  -0.817  -0.774  -0.983  -0.964  -0.901  -0.815  -0.795  -0.721
22    S        -0.466  -0.443  -0.372  -0.669  -0.633  -0.534  -0.651  -0.627  -0.526
23    A        -0.695  -0.728  -0.713  -0.556  -0.624  -0.603  -0.651  -0.688  -0.651
24    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    G         2.049   2.072   2.220   2.091   2.127   2.349   2.290   2.328   2.583
26    Y        -0.429  -0.421  -0.371  -0.388  -0.372  -0.328  -0.592  -0.581  -0.517
27    K        -0.834  -0.841  -0.774  -0.985  -1.002  -0.915  -0.815  -0.819  -0.720
28    D         0.568   0.577   0.406   0.621   0.641   0.347   0.492   0.506   0.216
29    Y        -0.695  -0.616  -0.694  -0.396  -0.281  -0.393  -0.651  -0.558  -0.630
30    S        -0.852  -0.868  -0.783  -0.713  -0.714  -0.582  -0.838  -0.845  -0.731
31    R         0.052   0.017  -0.149   0.148   0.096  -0.092   0.038  -0.008  -0.230
32    Y        -1.175  -1.174  -1.131  -0.920  -0.921  -0.865  -0.963  -0.957  -0.877
33    Q        -0.731  -0.651  -0.704  -0.782  -0.675  -0.731  -0.713  -0.630  -0.652
34    R         2.049   2.072   2.220   1.874   1.895   2.125   2.290   2.328   2.583
35    P         2.049   2.072   2.220   2.186   2.218   2.447   2.290   2.328   2.583
36    R         0.036   0.065   0.150  -0.331  -0.304  -0.162  -0.337  -0.300  -0.193
37    N        -0.834  -0.832  -0.771  -0.803  -0.807  -0.721  -0.815  -0.810  -0.717
38    V         0.818   0.820   0.927   0.691   0.680   0.830   0.413   0.405   0.533
39    S        -1.497  -1.512  -1.437  -1.283  -1.334  -1.193  -1.088  -1.097  -0.989
40    K        -0.207  -0.099  -0.228  -0.276  -0.099  -0.324  -0.337  -0.198  -0.347
41    V         0.374   0.396   0.315   0.448   0.456   0.346   0.163   0.176   0.050
42    K        -0.852  -0.859  -0.778  -0.987  -1.006  -0.896  -0.838  -0.840  -0.728
43    S         0.052  -0.007  -0.139   0.207   0.123  -0.100   0.038  -0.042  -0.217
44    I        -0.207  -0.273  -0.252  -0.230  -0.296  -0.268  -0.337  -0.404  -0.380
45    K        -0.530  -0.562  -0.658  -0.238  -0.283  -0.468  -0.462  -0.500  -0.590
46    E        -0.286  -0.276  -0.285  -0.444  -0.443  -0.414  -0.462  -0.450  -0.429
47    A         1.003   1.017   1.035   1.070   1.092   1.119   0.789   0.809   0.766
48    N         0.052   0.034  -0.146  -0.021  -0.060  -0.354   0.038   0.012  -0.226
49    E        -0.207  -0.215  -0.262  -0.445  -0.469  -0.556  -0.337  -0.354  -0.392
50    W         1.348   1.313   1.236   1.702   1.666   1.590   1.414   1.354   1.173
51    K         0.681   0.633   0.476   0.646   0.578   0.354   0.664   0.588   0.328
52    R        -1.175  -1.187  -1.119  -1.207  -1.240  -1.123  -0.963  -0.970  -0.867
53    Q        -0.207  -0.186  -0.256  -0.175  -0.161  -0.258  -0.337  -0.322  -0.388
54    V        -0.207  -0.243  -0.256  -0.088  -0.134  -0.159  -0.337  -0.379  -0.384
55    S        -0.852  -0.819  -0.779  -0.802  -0.768  -0.675  -0.838  -0.808  -0.728
56    K         0.374   0.307   0.316   0.205   0.110   0.095   0.163   0.071   0.056
57    E         1.348   1.313   1.236   1.237   1.188   1.087   1.414   1.354   1.173
58    I         1.348   1.270   1.239   1.505   1.405   1.377   1.414   1.280   1.179
59    K         0.374   0.379   0.310   0.365   0.366   0.241   0.163   0.156   0.045
60    Q        -0.731  -0.764  -0.743  -0.902  -0.979  -0.938  -0.713  -0.740  -0.690
61    K         0.052  -0.007  -0.139   0.109   0.045  -0.153   0.038  -0.042  -0.217
62    S        -0.731  -0.788  -0.734  -0.630  -0.705  -0.620  -0.713  -0.767  -0.681
63    T         0.374   0.307   0.326   0.523   0.430   0.437   0.163   0.071   0.074
64    R        -0.207  -0.165  -0.252  -0.464  -0.401  -0.562  -0.337  -0.275  -0.379
65    I         1.348   1.270   1.239   1.477   1.373   1.323   1.414   1.280   1.179
66    Y        -0.207  -0.215  -0.262  -0.070  -0.094  -0.122  -0.337  -0.354  -0.392
67    D         1.348   1.313   1.236   1.407   1.368   1.265   1.414   1.354   1.173
68    P         0.681   0.625   0.471   0.997   0.930   0.726   0.664   0.581   0.319
69    S        -0.731  -0.803  -0.738  -0.682  -0.789  -0.706  -0.713  -0.778  -0.684
70    L         1.348   1.344   1.236   1.308   1.315   1.172   1.414   1.407   1.174
71    N         0.237   0.223   0.272   0.140   0.142   0.216  -0.087  -0.093  -0.030
72    E         0.818   0.855   0.936   0.415   0.470   0.568   0.413   0.479   0.554
73    M        -1.053  -1.051  -1.076  -0.683  -0.708  -0.717  -0.838  -0.835  -0.824
74    Q         1.348   1.344   1.236   1.422   1.415   1.260   1.414   1.407   1.174
75    I         0.374   0.373   0.314   0.420   0.394   0.300   0.163   0.136   0.047
76    A         0.681   0.752   0.478   0.689   0.771   0.432   0.664   0.772   0.331
77    E         0.760   0.775   0.905   0.321   0.335   0.520   0.288   0.309   0.486
78    L         0.374   0.333   0.325   0.317   0.291   0.273   0.163   0.116   0.068
79    N         2.049   2.072   2.220   2.056   2.095   2.313   2.290   2.328   2.583
80    D         1.348   1.270   1.239   1.412   1.317   1.278   1.414   1.280   1.179
81    E        -0.530  -0.626  -0.661  -0.556  -0.719  -0.770  -0.462  -0.573  -0.593
82    L         0.237   0.188   0.266   0.043  -0.008   0.107  -0.087  -0.141  -0.036
83    N         2.049   2.072   2.220   2.056   2.095   2.313   2.290   2.328   2.583
84    N        -0.530  -0.621  -0.654  -0.580  -0.728  -0.813  -0.462  -0.567  -0.585
85    L         2.049   2.072   2.220   1.914   1.954   2.166   2.290   2.328   2.583
86    F         0.237   0.188   0.266   0.384   0.329   0.452  -0.087  -0.141  -0.036
87    K        -0.852  -0.818  -0.786  -1.011  -0.964  -0.915  -0.838  -0.807  -0.734
88    E         2.049   2.072   2.220   1.856   1.881   2.106   2.290   2.328   2.583
89    W         0.052   0.047  -0.132   0.095   0.089  -0.164   0.038   0.028  -0.207
90    K        -0.731  -0.742  -0.742  -0.606  -0.633  -0.650  -0.713  -0.723  -0.689
91    R         0.052   0.080  -0.120   0.069   0.086  -0.178   0.038   0.075  -0.192
92    W         2.049   2.072   2.220   2.288   2.321   2.552   2.290   2.328   2.583
93    Q        -0.207  -0.216  -0.251  -0.370  -0.378  -0.431  -0.337  -0.337  -0.378
94    W        -1.175  -1.162  -1.132  -0.921  -0.927  -0.850  -0.963  -0.951  -0.878
95    H         0.818   0.845   0.943   0.802   0.844   0.971   0.413   0.459   0.569
96    I         1.348   1.270   1.239   1.477   1.373   1.323   1.414   1.280   1.179
97    D         0.681   0.740   0.492   0.621   0.693   0.335   0.664   0.754   0.354
98    H        -0.731  -0.746  -0.722  -0.669  -0.713  -0.653  -0.713  -0.732  -0.670
99    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   L         2.049   2.072   2.220   1.909   1.946   2.161   2.290   2.328   2.583
101   M        -0.097  -0.114  -0.219   0.148   0.134  -0.027  -0.161  -0.182  -0.324
102   E         1.286   1.296   1.198   1.392   1.410   1.244   1.309   1.324   1.100
103   K        -0.695  -0.735  -0.726  -0.493  -0.561  -0.575  -0.651  -0.694  -0.664
104   K         0.181   0.187   0.231  -0.053  -0.047   0.007  -0.161  -0.153  -0.087
105   T         0.568   0.576   0.409   0.804   0.819   0.562   0.492   0.506   0.220
106   K        -0.834  -0.846  -0.781  -0.825  -0.856  -0.742  -0.815  -0.822  -0.727
107   R        -0.695  -0.689  -0.700  -0.660  -0.648  -0.662  -0.651  -0.643  -0.636
108   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   R        -0.429  -0.413  -0.365  -0.655  -0.605  -0.587  -0.592  -0.574  -0.510
110   L        -0.429  -0.385  -0.343  -0.681  -0.601  -0.561  -0.592  -0.537  -0.483
111   E        -0.945  -0.934  -0.835  -1.184  -1.152  -1.031  -0.913  -0.900  -0.776
112   D        -0.945  -0.934  -0.835  -0.954  -0.950  -0.794  -0.913  -0.900  -0.776
113   S        -0.945  -0.934  -0.835  -1.058  -1.043  -0.901  -0.913  -0.900  -0.776
114   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   N        -0.530  -0.493  -0.632  -0.219  -0.165  -0.339  -0.462  -0.421  -0.561
119   S        -0.530  -0.542  -0.641  -0.257  -0.270  -0.433  -0.462  -0.474  -0.571
120   G         1.348   1.313   1.236   1.508   1.473   1.371   1.414   1.354   1.173
121   K         0.052  -0.007  -0.139   0.140   0.062  -0.104   0.038  -0.042  -0.217
122   L         0.271   0.258   0.281   0.071   0.051   0.063   0.002  -0.022  -0.002
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
127   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
131   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   I        -0.207  -0.221  -0.239  -0.116  -0.127  -0.172  -0.337  -0.350  -0.364
135   N        -0.530  -0.519  -0.410  -0.878  -0.846  -0.707  -0.713  -0.699  -0.564
136   G         0.681   0.625   0.471   0.910   0.845   0.624   0.664   0.581   0.319
137   K         0.374   0.337   0.319   0.427   0.388   0.319   0.163   0.122   0.063
138   R         0.681   0.790   0.495   0.628   0.764   0.352   0.664   0.828   0.359
139   Y         2.049   2.072   2.220   2.166   2.193   2.426   2.290   2.328   2.583
140   F         0.374   0.305   0.323   0.578   0.483   0.501   0.163   0.067   0.067
141   G         2.049   2.072   2.220   2.117   2.155   2.376   2.290   2.328   2.583
142   R         2.049   2.072   2.220   1.874   1.895   2.125   2.290   2.328   2.583
143   A         2.049   2.072   2.220   2.088   2.121   2.346   2.290   2.328   2.583
144   L         0.115   0.148   0.188  -0.324  -0.271  -0.258  -0.212  -0.164  -0.134
145   E         1.348   1.344   1.236   1.237   1.229   1.088   1.414   1.407   1.174
146   L         2.049   2.072   2.220   1.914   1.954   2.166   2.290   2.328   2.583
147   P         2.049   2.072   2.220   2.186   2.218   2.447   2.290   2.328   2.583
148   E         0.237   0.270   0.272  -0.020   0.023   0.041  -0.087  -0.041  -0.027
149   V         1.348   1.270   1.239   1.505   1.402   1.373   1.414   1.280   1.179
150   K         0.052   0.051  -0.133   0.046   0.034  -0.245   0.038   0.033  -0.208
151   E         0.374   0.338   0.315   0.087   0.017  -0.051   0.163   0.102   0.053
152   W        -0.731  -0.744  -0.722  -0.626  -0.656  -0.584  -0.713  -0.723  -0.671
153   L        -0.207  -0.281  -0.253  -0.179  -0.258  -0.209  -0.337  -0.422  -0.379
154   K        -1.053  -1.027  -1.070  -1.021  -0.976  -1.038  -0.838  -0.811  -0.818
155   Q        -0.731  -0.665  -0.724  -0.784  -0.680  -0.796  -0.713  -0.644  -0.672
156   S        -0.852  -0.871  -0.785  -0.840  -0.858  -0.735  -0.838  -0.848  -0.733
157   Q        -0.731  -0.765  -0.718  -0.776  -0.827  -0.741  -0.713  -0.743  -0.665
158   R        -0.731  -0.769  -0.728  -0.966  -1.010  -0.979  -0.713  -0.744  -0.676
159   -        -1.203  -1.134  -1.125  -1.011  -0.879  -0.907  -0.978  -0.912  -0.869
160   -        -1.203  -1.188  -1.136  -1.207  -1.162  -1.098  -0.978  -0.964  -0.878
161   Q        -1.497  -1.514  -1.435  -1.211  -1.239  -1.111  -1.088  -1.098  -0.988
162   N        -0.731  -0.711  -0.715  -0.858  -0.829  -0.840  -0.713  -0.691  -0.664
163   D        -1.175  -1.134  -1.112  -1.259  -1.200  -1.169  -0.963  -0.924  -0.862
164   G        -1.203  -1.192  -1.145  -1.352  -1.327  -1.273  -0.978  -0.966  -0.886
165   G        -0.466  -0.439  -0.371  -0.684  -0.649  -0.560  -0.651  -0.624  -0.525
166   S        -0.834  -0.814  -0.768  -0.913  -0.891  -0.800  -0.815  -0.794  -0.715
167   I        -1.571  -1.566  -1.474  -1.380  -1.375  -1.234  -1.142  -1.134  -1.016
168   N        -0.695  -0.677  -0.715  -0.702  -0.684  -0.718  -0.651  -0.629  -0.653
169   T        -0.834  -0.847  -0.773  -0.763  -0.775  -0.659  -0.815  -0.823  -0.719
170   K        -1.203  -1.194  -1.149  -1.342  -1.326  -1.267  -0.978  -0.967  -0.890
171   C        -0.945  -0.940  -0.835  -0.873  -0.867  -0.711  -0.913  -0.905  -0.776
172   I         0.087   0.103   0.184  -0.244  -0.225  -0.105  -0.272  -0.251  -0.148
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   P        -0.429  -0.417  -0.356  -0.587  -0.571  -0.485  -0.592  -0.577  -0.499
177   K        -1.175  -1.165  -1.116  -1.239  -1.228  -1.133  -0.963  -0.953  -0.865
178   D         0.237   0.268   0.270  -0.151  -0.116  -0.100  -0.087  -0.049  -0.033
179   R        -1.175  -1.157  -1.116  -1.312  -1.279  -1.217  -0.963  -0.947  -0.865
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   N        -0.852  -0.824  -0.783  -0.916  -0.870  -0.818  -0.838  -0.812  -0.732
191   D         0.681   0.758   0.490   0.775   0.884   0.491   0.664   0.781   0.351
192   F        -0.408  -0.390  -0.347  -0.282  -0.255  -0.178  -0.587  -0.571  -0.498
193   Y        -1.497  -1.507  -1.445  -1.108  -1.118  -1.026  -1.088  -1.093  -0.996
194   Y         0.681   0.637   0.479   0.967   0.902   0.700   0.664   0.594   0.332
195   H        -0.731  -0.743  -0.727  -0.413  -0.439  -0.383  -0.713  -0.725  -0.674
196   G         2.049   2.072   2.220   2.117   2.155   2.376   2.290   2.328   2.583
197   K        -1.053  -1.067  -1.092  -0.744  -0.766  -0.820  -0.838  -0.850  -0.839
198   V        -1.175  -1.196  -1.133  -0.877  -0.892  -0.795  -0.963  -0.976  -0.879
199   T        -0.408  -0.398  -0.347  -0.406  -0.397  -0.298  -0.587  -0.580  -0.498
200   -         0.168   0.174   0.221  -0.087  -0.068  -0.013  -0.157  -0.146  -0.092
201   -        -0.424  -0.410  -0.346  -0.616  -0.584  -0.499  -0.601  -0.583  -0.494
202   -        -0.854  -0.866  -0.785  -0.934  -0.952  -0.824  -0.824  -0.836  -0.727
203   -         1.118   1.131   1.109   1.030   1.050   0.968   1.009   1.027   0.921
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   A        -0.695  -0.681  -0.714  -0.619  -0.596  -0.659  -0.651  -0.635  -0.652
249   A        -1.571  -1.566  -1.474  -1.556  -1.541  -1.416  -1.142  -1.134  -1.016
250   L         2.049   2.072   2.220   1.909   1.946   2.161   2.290   2.328   2.583
251   T        -1.203  -1.213  -1.137  -1.085  -1.109  -0.972  -0.978  -0.984  -0.880
252   E        -0.097  -0.123  -0.210  -0.148  -0.192  -0.316  -0.161  -0.196  -0.311
253   F         0.760   0.775   0.904   0.693   0.710   0.905   0.288   0.308   0.484
254   E         1.348   1.270   1.239   1.215   1.102   1.051   1.414   1.280   1.179
255   A        -0.286  -0.341  -0.281  -0.452  -0.510  -0.440  -0.462  -0.514  -0.425
256   N        -0.731  -0.708  -0.709  -0.741  -0.694  -0.686  -0.713  -0.686  -0.657
257   W         0.052  -0.036  -0.141   0.125  -0.007  -0.118   0.038  -0.081  -0.219
258   T         0.237   0.269   0.263   0.065   0.100   0.135  -0.087  -0.043  -0.045
259   S        -0.852  -0.851  -0.783  -1.112  -1.129  -1.013  -0.838  -0.833  -0.731
260   I        -1.175  -1.173  -1.124  -1.284  -1.291  -1.222  -0.963  -0.959  -0.871
261   L         0.052  -0.015  -0.135   0.074  -0.027  -0.217   0.038  -0.055  -0.212
262   K        -0.424  -0.418  -0.354  -0.488  -0.471  -0.382  -0.601  -0.593  -0.503
263   A        -0.854  -0.840  -0.791  -1.058  -1.042  -1.007  -0.824  -0.807  -0.733
264   H        -0.327  -0.269  -0.293  -0.195  -0.094  -0.153  -0.488  -0.417  -0.432
265   Y        -0.854  -0.843  -0.798  -0.830  -0.815  -0.730  -0.824  -0.809  -0.740
266   -        -0.429  -0.428  -0.355  -0.630  -0.633  -0.552  -0.592  -0.591  -0.498
267   N        -0.262  -0.204  -0.266  -0.359  -0.268  -0.423  -0.379  -0.302  -0.385
268   V        -1.284  -1.277  -1.182  -1.127  -1.122  -0.972  -1.046  -1.037  -0.916
269   P        -0.429  -0.418  -0.365  -0.471  -0.445  -0.391  -0.592  -0.579  -0.510
270   V        -0.429  -0.442  -0.373  -0.361  -0.382  -0.273  -0.592  -0.608  -0.520
271   N        -0.207  -0.172  -0.256  -0.067  -0.004  -0.125  -0.337  -0.287  -0.386
272   E        -1.053  -1.007  -1.070  -1.022  -0.929  -1.093  -0.838  -0.792  -0.818
273   D        -1.053  -1.051  -1.076  -0.941  -0.942  -0.946  -0.838  -0.835  -0.824
274   E        -1.175  -1.192  -1.118  -1.140  -1.171  -1.038  -0.963  -0.973  -0.867
275   E        -1.053  -1.053  -1.064  -1.062  -1.069  -1.082  -0.838  -0.837  -0.813
276   E        -1.175  -1.167  -1.125  -1.223  -1.227  -1.139  -0.963  -0.953  -0.872
277   M        -1.497  -1.471  -1.430  -1.227  -1.197  -1.121  -1.088  -1.064  -0.984
278   S        -0.852  -0.835  -0.782  -0.662  -0.638  -0.549  -0.838  -0.820  -0.730
279   R        -1.175  -1.189  -1.127  -1.136  -1.174  -1.109  -0.963  -0.971  -0.874
280   Q        -0.731  -0.711  -0.720  -0.547  -0.529  -0.526  -0.713  -0.690  -0.666
281   T        -1.203  -1.190  -1.148  -1.011  -0.988  -0.899  -0.978  -0.964  -0.889
282   Q        -1.203  -1.213  -1.137  -0.872  -0.887  -0.771  -0.978  -0.984  -0.880
283   E        -0.695  -0.717  -0.712  -0.714  -0.747  -0.731  -0.651  -0.674  -0.650
284   I        -1.203  -1.207  -1.140  -1.057  -1.088  -0.970  -0.978  -0.979  -0.882
285   H        -0.731  -0.709  -0.716  -0.738  -0.722  -0.676  -0.713  -0.688  -0.664
286   V        -0.207  -0.251  -0.255  -0.095  -0.164  -0.171  -0.337  -0.399  -0.386
287   P         2.049   2.072   2.220   2.186   2.218   2.447   2.290   2.328   2.583
288   T         0.681   0.771   0.480   0.965   1.088   0.660   0.664   0.800   0.335
289   L        -1.497  -1.507  -1.445  -1.471  -1.489  -1.391  -1.088  -1.093  -0.996
290   A        -1.053  -1.051  -1.076  -0.964  -0.963  -1.029  -0.838  -0.835  -0.824
291   D        -0.207  -0.255  -0.246  -0.279  -0.333  -0.349  -0.337  -0.383  -0.372
292   M         0.374   0.393   0.323   0.481   0.498   0.398   0.163   0.173   0.067
293   E         0.374   0.430   0.331   0.253   0.319   0.203   0.163   0.238   0.080
294   H        -1.175  -1.160  -1.127  -1.188  -1.182  -1.114  -0.963  -0.949  -0.874
295   W        -0.530  -0.555  -0.640  -0.152  -0.183  -0.357  -0.462  -0.493  -0.569
296   L         1.348   1.387   1.243   1.308   1.368   1.182   1.414   1.478   1.187
297   V         0.374   0.428   0.328   0.385   0.451   0.292   0.163   0.233   0.074
298   Q        -0.408  -0.354  -0.336  -0.650  -0.581  -0.543  -0.587  -0.527  -0.483
299   R         0.374   0.426   0.322   0.094   0.157  -0.037   0.163   0.232   0.065
300   R         1.348   1.387   1.243   1.236   1.279   1.081   1.414   1.478   1.187
301   K         0.818   0.847   0.933   0.368   0.415   0.502   0.413   0.462   0.547
302   K        -0.731  -0.715  -0.724  -0.912  -0.894  -0.917  -0.713  -0.695  -0.673
303   K        -0.852  -0.848  -0.778  -1.132  -1.105  -1.017  -0.838  -0.828  -0.727
304   L         1.348   1.415   1.241   1.308   1.401   1.180   1.414   1.524   1.184
305   M        -0.530  -0.427  -0.629  -0.433  -0.278  -0.571  -0.462  -0.338  -0.557
306   D        -0.852  -0.862  -0.779  -0.835  -0.822  -0.717  -0.838  -0.841  -0.728
307   E        -0.731  -0.701  -0.716  -0.908  -0.872  -0.933  -0.713  -0.683  -0.664
308   L         0.681   0.625   0.471   0.733   0.675   0.470   0.664   0.581   0.319
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   L        -0.695  -0.683  -0.726  -0.831  -0.807  -0.925  -0.651  -0.637  -0.665
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P21374
Output conservation file - output/P21374
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
