1     M         1.041   1.059   1.138   1.247   1.270   1.376   1.097   1.121   1.238
2     S         1.041   1.059   1.138   1.008   1.030   1.164   1.097   1.121   1.238
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     S        -1.613  -1.628  -1.462  -1.556  -1.575  -1.306  -1.514  -1.515  -1.266
10    A        -0.400  -0.368  -0.175  -0.856  -0.819  -0.488  -0.785  -0.738  -0.447
11    A         0.258   0.087  -0.068   0.141  -0.074  -0.279   0.274   0.021  -0.260
12    G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
13    Y        -0.400  -0.370  -0.176  -0.534  -0.487  -0.201  -0.785  -0.740  -0.448
14    D         1.041   1.059   1.138   1.055   1.079   1.206   1.097   1.121   1.238
15    R         1.041   1.059   1.138   1.102   1.128   1.247   1.097   1.121   1.238
16    H         0.258   0.087  -0.068   0.651   0.420   0.109   0.274   0.021  -0.260
17    I         1.041   1.059   1.138   0.940   0.971   1.104   1.097   1.121   1.238
18    T         1.041   1.059   1.138   1.008   1.034   1.164   1.097   1.121   1.238
19    I         0.258   0.087  -0.068   0.271   0.052  -0.198   0.274   0.021  -0.260
20    F         1.041   1.059   1.138   1.136   1.158   1.277   1.097   1.121   1.238
21    S         1.041   1.059   1.138   1.008   1.030   1.164   1.097   1.121   1.238
22    P         0.258   0.206  -0.059   0.467   0.402  -0.034   0.274   0.199  -0.245
23    E         0.258   0.206  -0.059   0.326   0.272  -0.101   0.274   0.199  -0.245
24    G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
25    R         1.041   1.059   1.138   1.102   1.128   1.247   1.097   1.121   1.238
26    L         1.041   1.059   1.138   1.029   1.055   1.182   1.097   1.121   1.238
27    Y         1.041   1.059   1.138   1.110   1.144   1.254   1.097   1.121   1.238
28    Q         1.041   1.059   1.138   1.151   1.173   1.290   1.097   1.121   1.238
29    V         1.041   1.059   1.138   1.017   1.038   1.172   1.097   1.121   1.238
30    E         1.041   1.059   1.138   0.976   1.007   1.135   1.097   1.121   1.238
31    Y         1.041   1.059   1.138   1.110   1.144   1.254   1.097   1.121   1.238
32    A         1.041   1.059   1.138   0.798   0.823   0.978   1.097   1.121   1.238
33    F         1.041   1.059   1.138   1.136   1.158   1.277   1.097   1.121   1.238
34    K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
35    A         1.041   1.059   1.138   0.798   0.823   0.978   1.097   1.121   1.238
36    T        -2.065  -2.077  -1.892  -1.975  -1.985  -1.710  -1.726  -1.715  -1.445
37    N         0.258   0.206  -0.059   0.537   0.475   0.032   0.274   0.199  -0.245
38    Q        -1.569  -1.666  -1.467  -1.501  -1.622  -1.371  -1.490  -1.556  -1.272
39    T        -1.480  -1.324  -1.428  -1.597  -1.373  -1.476  -1.373  -1.188  -1.233
40    N         0.258   0.087  -0.068   0.536   0.312   0.015   0.274   0.021  -0.260
41    I        -0.128  -0.072  -0.122  -0.267  -0.178  -0.288  -0.314  -0.229  -0.353
42    N        -0.984  -0.980  -0.901  -0.948  -0.926  -0.778  -1.138  -1.109  -0.960
43    S         1.041   1.059   1.138   1.008   1.030   1.164   1.097   1.121   1.238
44    L        -0.830  -0.926  -0.887  -0.840  -0.967  -0.970  -0.902  -1.003  -0.943
45    A        -0.334  -0.265  -0.150  -0.686  -0.561  -0.413  -0.667  -0.555  -0.402
46    V        -0.334  -0.291  -0.168  -0.600  -0.531  -0.367  -0.667  -0.599  -0.435
47    R        -0.334  -0.327  -0.169  -0.489  -0.490  -0.269  -0.667  -0.663  -0.436
48    G         0.258   0.255  -0.054   0.335   0.330  -0.125   0.274   0.269  -0.236
49    K         0.258   0.326  -0.049   0.296   0.380  -0.108   0.274   0.368  -0.227
50    D        -0.830  -0.879  -0.892  -0.715  -0.795  -0.824  -0.902  -0.972  -0.950
51    C        -0.830  -0.752  -0.862  -0.597  -0.472  -0.766  -0.902  -0.785  -0.908
52    T        -0.830  -0.699  -0.880  -1.038  -0.864  -1.093  -0.902  -0.740  -0.933
53    V         0.258   0.087  -0.068   0.389   0.182  -0.019   0.274   0.021  -0.260
54    V        -0.830  -0.656  -0.873  -0.849  -0.601  -0.948  -0.902  -0.677  -0.925
55    I        -0.488  -0.493  -0.840  -0.388  -0.393  -0.910  -0.432  -0.439  -0.880
56    S         0.258   0.362  -0.047   0.367   0.485  -0.033   0.274   0.416  -0.225
57    Q         1.041   1.059   1.138   1.151   1.173   1.290   1.097   1.121   1.238
58    K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
59    K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
60    V        -0.334  -0.253  -0.151  -0.600  -0.459  -0.331  -0.667  -0.534  -0.405
61    P         0.258   0.319  -0.053   0.471   0.546  -0.010   0.274   0.358  -0.234
62    D         1.041   1.059   1.138   1.055   1.079   1.206   1.097   1.121   1.238
63    K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
64    L         1.041   1.059   1.138   1.029   1.055   1.182   1.097   1.121   1.238
65    L        -0.128  -0.241  -0.159  -0.209  -0.419  -0.339  -0.314  -0.513  -0.419
66    D         1.041   1.059   1.138   1.055   1.079   1.206   1.097   1.121   1.238
67    P         0.258   0.087  -0.068   0.443   0.201  -0.120   0.274   0.021  -0.260
68    T        -1.480  -1.302  -1.426  -1.471  -1.231  -1.428  -1.373  -1.185  -1.233
69    T         0.258   0.206  -0.059   0.338   0.275  -0.131   0.274   0.199  -0.245
70    V         1.041   1.059   1.138   1.017   1.038   1.172   1.097   1.121   1.238
71    S         0.258   0.087  -0.068   0.329   0.097  -0.172   0.274   0.021  -0.260
72    Y        -0.128  -0.241  -0.159  -0.007  -0.172  -0.070  -0.314  -0.513  -0.419
73    I         0.258   0.087  -0.068   0.271   0.052  -0.198   0.274   0.021  -0.260
74    F         1.041   1.059   1.138   1.136   1.158   1.277   1.097   1.121   1.238
75    C        -2.065  -2.020  -1.880  -1.810  -1.760  -1.509  -1.726  -1.684  -1.437
76    I         0.258   0.255  -0.054   0.271   0.274  -0.175   0.274   0.269  -0.236
77    S        -0.984  -0.979  -0.901  -1.164  -1.168  -1.060  -1.138  -1.125  -0.962
78    R        -1.120  -1.109  -0.933  -1.144  -1.151  -0.937  -1.255  -1.241  -0.998
79    T        -1.480  -1.531  -1.452  -1.362  -1.424  -1.295  -1.373  -1.403  -1.257
80    I         0.258   0.206  -0.059   0.271   0.213  -0.184   0.274   0.199  -0.245
81    G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
82    M        -2.065  -1.996  -1.882  -1.643  -1.558  -1.485  -1.726  -1.665  -1.438
83    V         0.258   0.255  -0.054   0.389   0.385   0.001   0.274   0.269  -0.236
84    V        -1.841  -1.894  -1.873  -1.760  -1.832  -1.783  -1.490  -1.543  -1.430
85    N        -0.128  -0.001  -0.099  -0.142   0.040  -0.113  -0.314  -0.115  -0.313
86    G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
87    P        -0.984  -0.897  -0.899  -1.009  -0.895  -0.846  -1.138  -1.023  -0.957
88    I         0.258   0.255  -0.054   0.271   0.274  -0.175   0.274   0.269  -0.236
89    P        -0.400  -0.363  -0.174  -0.754  -0.719  -0.401  -0.785  -0.728  -0.446
90    D         1.041   1.059   1.138   1.055   1.079   1.206   1.097   1.121   1.238
91    A         1.041   1.059   1.138   0.798   0.823   0.978   1.097   1.121   1.238
92    R         1.041   1.059   1.138   1.102   1.128   1.247   1.097   1.121   1.238
93    N        -0.334  -0.265  -0.150  -0.647  -0.548  -0.344  -0.667  -0.555  -0.402
94    A        -1.569  -1.578  -1.452  -1.635  -1.611  -1.434  -1.490  -1.477  -1.259
95    A        -0.128  -0.194  -0.153  -0.409  -0.525  -0.457  -0.314  -0.431  -0.409
96    L        -2.065  -2.057  -1.884  -1.873  -1.881  -1.653  -1.726  -1.711  -1.439
97    R         1.041   1.059   1.138   1.102   1.128   1.247   1.097   1.121   1.238
98    A         0.258   0.255  -0.054   0.171   0.172  -0.174   0.274   0.269  -0.236
99    K        -0.984  -0.980  -0.901  -1.052  -1.017  -0.889  -1.138  -1.109  -0.960
100   A        -1.208  -1.158  -0.933  -1.533  -1.460  -1.128  -1.373  -1.307  -0.997
101   E         1.041   1.059   1.138   0.976   1.007   1.135   1.097   1.121   1.238
102   A         1.041   1.059   1.138   0.798   0.823   0.978   1.097   1.121   1.238
103   A        -0.488  -0.442  -0.829  -0.537  -0.479  -1.014  -0.432  -0.373  -0.865
104   E         1.041   1.059   1.138   0.976   1.007   1.135   1.097   1.121   1.238
105   F         1.041   1.059   1.138   1.136   1.158   1.277   1.097   1.121   1.238
106   R         0.258   0.087  -0.068   0.426   0.202  -0.083   0.274   0.021  -0.260
107   Y         1.041   1.059   1.138   1.110   1.144   1.254   1.097   1.121   1.238
108   K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
109   Y        -0.488  -0.701  -0.860  -0.170  -0.436  -0.697  -0.432  -0.707  -0.905
110   G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
111   Y         1.041   1.059   1.138   1.110   1.144   1.254   1.097   1.121   1.238
112   D        -0.984  -1.073  -0.910  -1.074  -1.174  -0.927  -1.138  -1.214  -0.972
113   M         0.258   0.255  -0.054   0.567   0.563   0.048   0.274   0.269  -0.236
114   P         1.041   1.059   1.138   1.142   1.166   1.283   1.097   1.121   1.238
115   C        -0.128  -0.021  -0.097   0.077   0.238   0.037  -0.314  -0.146  -0.310
116   D        -0.830  -0.752  -0.862  -0.803  -0.674  -0.886  -0.902  -0.785  -0.908
117   V        -1.480  -1.416  -1.440  -1.418  -1.332  -1.381  -1.373  -1.285  -1.244
118   L         1.041   1.059   1.138   1.029   1.055   1.182   1.097   1.121   1.238
119   A         0.258   0.326  -0.049   0.127   0.211  -0.287   0.274   0.368  -0.227
120   K         0.258   0.326  -0.049   0.289   0.374  -0.127   0.274   0.368  -0.227
121   R         1.041   1.059   1.138   1.102   1.128   1.247   1.097   1.121   1.238
122   M         0.258   0.206  -0.059   0.567   0.500   0.038   0.274   0.199  -0.245
123   A         1.041   1.059   1.138   0.798   0.823   0.978   1.097   1.121   1.238
124   N         1.041   1.059   1.138   1.208   1.235   1.341   1.097   1.121   1.238
125   L        -0.400  -0.358  -0.172  -0.736  -0.670  -0.376  -0.785  -0.719  -0.442
126   S        -0.488  -0.602  -0.851  -0.326  -0.512  -0.888  -0.432  -0.586  -0.894
127   Q         1.041   1.059   1.138   1.151   1.173   1.290   1.097   1.121   1.238
128   I        -1.208  -1.126  -0.926  -1.466  -1.336  -1.037  -1.373  -1.269  -0.989
129   Y         0.258   0.087  -0.068   0.440   0.222  -0.063   0.274   0.021  -0.260
130   T         1.041   1.059   1.138   1.008   1.034   1.164   1.097   1.121   1.238
131   Q         1.041   1.059   1.138   1.151   1.173   1.290   1.097   1.121   1.238
132   R         1.041   1.059   1.138   1.102   1.128   1.247   1.097   1.121   1.238
133   A         1.041   1.059   1.138   0.798   0.823   0.978   1.097   1.121   1.238
134   Y        -0.488  -0.701  -0.860  -0.236  -0.540  -0.857  -0.432  -0.707  -0.905
135   M         1.041   1.059   1.138   1.247   1.270   1.376   1.097   1.121   1.238
136   R         1.041   1.059   1.138   1.102   1.128   1.247   1.097   1.121   1.238
137   P         1.041   1.059   1.138   1.142   1.166   1.283   1.097   1.121   1.238
138   L         0.258   0.206  -0.059   0.373   0.315  -0.074   0.274   0.199  -0.245
139   G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
140   V         0.258   0.255  -0.054   0.337   0.331  -0.141   0.274   0.269  -0.236
141   I        -0.400  -0.363  -0.174  -0.908  -0.856  -0.533  -0.785  -0.728  -0.446
142   L        -0.830  -0.931  -0.905  -0.723  -0.870  -0.835  -0.902  -1.034  -0.965
143   T         1.041   1.059   1.138   1.008   1.034   1.164   1.097   1.121   1.238
144   F        -0.334  -0.356  -0.175  -0.448  -0.515  -0.250  -0.667  -0.715  -0.448
145   V        -0.830  -0.780  -0.883  -0.840  -0.811  -0.881  -0.902  -0.865  -0.939
146   S        -1.120  -1.090  -0.921  -1.301  -1.299  -1.058  -1.255  -1.219  -0.984
147   V        -0.488  -0.448  -0.832  -0.310  -0.261  -0.835  -0.432  -0.381  -0.870
148   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
149   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   D         1.041   1.059   1.138   1.055   1.079   1.206   1.097   1.121   1.238
152   E        -0.830  -0.931  -0.905  -0.849  -1.007  -0.979  -0.902  -1.034  -0.965
153   E        -0.488  -0.331  -0.827  -0.350  -0.150  -0.854  -0.432  -0.234  -0.862
154   L        -2.065  -2.136  -1.895  -1.874  -1.984  -1.678  -1.726  -1.762  -1.448
155   G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
156   P         0.258   0.374  -0.046   0.471   0.610   0.002   0.274   0.432  -0.223
157   S        -1.569  -1.522  -1.451  -1.557  -1.506  -1.437  -1.490  -1.433  -1.258
158   I        -0.334  -0.356  -0.175  -0.621  -0.667  -0.380  -0.667  -0.715  -0.448
159   Y        -0.334  -0.243  -0.155  -0.406  -0.251  -0.160  -0.667  -0.516  -0.411
160   K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
161   T        -0.488  -0.557  -0.842  -0.032  -0.147  -0.643  -0.432  -0.535  -0.882
162   D         1.041   1.059   1.138   1.055   1.079   1.206   1.097   1.121   1.238
163   P         1.041   1.059   1.138   1.142   1.166   1.283   1.097   1.121   1.238
164   A         1.041   1.059   1.138   0.798   0.823   0.978   1.097   1.121   1.238
165   G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
166   Y         0.258   0.087  -0.068   0.458   0.250  -0.012   0.274   0.021  -0.260
167   Y         0.258   0.326  -0.049   0.458   0.549   0.020   0.274   0.368  -0.227
168   V        -0.984  -1.049  -0.901  -1.130  -1.205  -0.999  -1.138  -1.178  -0.961
169   G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
170   Y        -0.128  -0.021  -0.097  -0.106   0.066  -0.114  -0.314  -0.146  -0.310
171   K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
172   A         0.258   0.206  -0.059   0.126   0.063  -0.306   0.274   0.199  -0.245
173   T        -0.128  -0.021  -0.097  -0.204  -0.042  -0.195  -0.314  -0.146  -0.310
174   A         0.258   0.087  -0.068   0.127  -0.097  -0.319   0.274   0.021  -0.260
175   T        -0.830  -0.879  -0.905  -0.915  -1.066  -1.102  -0.902  -0.995  -0.965
176   G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
177   P         1.041   1.059   1.138   1.142   1.166   1.283   1.097   1.121   1.238
178   K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
179   Q         1.041   1.059   1.138   1.151   1.173   1.290   1.097   1.121   1.238
180   Q         0.258   0.087  -0.068   0.480   0.252  -0.030   0.274   0.021  -0.260
181   E         1.041   1.059   1.138   0.976   1.007   1.135   1.097   1.121   1.238
182   I        -1.480  -1.495  -1.453  -1.637  -1.663  -1.580  -1.373  -1.381  -1.258
183   T        -1.480  -1.616  -1.454  -1.353  -1.553  -1.337  -1.373  -1.496  -1.260
184   T        -0.984  -0.985  -0.906  -0.997  -0.983  -0.864  -1.138  -1.135  -0.968
185   N        -2.921  -2.880  -2.548  -2.331  -2.248  -1.875  -2.078  -2.032  -1.652
186   L         1.041   1.059   1.138   1.029   1.055   1.182   1.097   1.121   1.238
187   E         1.041   1.059   1.138   0.976   1.007   1.135   1.097   1.121   1.238
188   N        -0.128  -0.001  -0.099  -0.202  -0.020  -0.162  -0.314  -0.115  -0.313
189   H        -1.480  -1.498  -1.453  -1.300  -1.330  -1.233  -1.373  -1.383  -1.258
190   F        -0.830  -0.750  -0.878  -0.688  -0.598  -0.798  -0.902  -0.814  -0.931
191   K         1.041   1.059   1.138   0.946   0.973   1.109   1.097   1.121   1.238
192   K         0.258   0.206  -0.059   0.305   0.249  -0.101   0.274   0.199  -0.245
193   S        -2.425  -2.366  -2.225  -2.252  -2.183  -2.025  -1.843  -1.789  -1.552
194   K        -2.201  -2.177  -1.897  -2.161  -2.137  -1.714  -1.843  -1.805  -1.450
195   I        -2.561  -2.457  -2.234  -2.274  -2.146  -1.891  -1.961  -1.869  -1.558
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   N        -1.769  -1.691  -1.481  -1.903  -1.829  -1.457  -1.668  -1.585  -1.284
201   E        -2.201  -2.085  -1.896  -2.157  -1.977  -1.722  -1.843  -1.735  -1.449
202   E        -0.984  -1.062  -0.911  -1.144  -1.234  -1.013  -1.138  -1.196  -0.972
203   S        -1.480  -1.498  -1.453  -1.353  -1.367  -1.327  -1.373  -1.383  -1.258
204   W        -0.488  -0.602  -0.851   0.018  -0.152  -0.621  -0.432  -0.586  -0.894
205   E        -2.065  -2.073  -1.893  -1.945  -1.973  -1.676  -1.726  -1.720  -1.447
206   K        -1.120  -1.138  -0.937  -1.322  -1.360  -1.063  -1.255  -1.277  -1.002
207   V        -0.400  -0.367  -0.175  -0.695  -0.649  -0.342  -0.785  -0.735  -0.447
208   V         0.258   0.319  -0.053   0.346   0.419  -0.112   0.274   0.358  -0.234
209   E         1.041   1.059   1.138   0.976   1.007   1.135   1.097   1.121   1.238
210   F        -0.830  -0.931  -0.905  -0.710  -0.886  -0.891  -0.902  -1.034  -0.965
211   A        -0.334  -0.342  -0.173  -0.761  -0.785  -0.490  -0.667  -0.691  -0.444
212   I         1.041   1.059   1.138   0.940   0.971   1.104   1.097   1.121   1.238
213   T        -1.190  -1.245  -1.414  -0.960  -1.042  -1.330  -1.020  -1.088  -1.219
214   H        -1.480  -1.356  -1.439  -1.518  -1.395  -1.361  -1.373  -1.255  -1.246
215   M        -0.128  -0.001  -0.099  -0.109   0.070  -0.079  -0.314  -0.115  -0.313
216   I        -0.984  -1.062  -0.911  -1.113  -1.177  -0.930  -1.138  -1.196  -0.972
217   D        -1.208  -1.176  -0.939  -1.402  -1.364  -1.013  -1.373  -1.327  -1.004
218   A        -1.208  -1.138  -0.937  -1.525  -1.415  -1.136  -1.373  -1.285  -1.002
219   L         0.258   0.326  -0.049   0.349   0.437  -0.122   0.274   0.368  -0.227
220   G        -0.334  -0.356  -0.175  -0.574  -0.637  -0.350  -0.667  -0.715  -0.448
221   T        -0.488  -0.493  -0.840  -0.283  -0.287  -0.771  -0.432  -0.439  -0.880
222   E        -0.334  -0.240  -0.154  -0.547  -0.379  -0.289  -0.667  -0.511  -0.410
223   F         1.041   1.059   1.138   1.136   1.158   1.277   1.097   1.121   1.238
224   S        -1.208  -1.126  -0.926  -1.434  -1.322  -1.013  -1.373  -1.269  -0.989
225   K         0.258   0.087  -0.068   0.275   0.052  -0.197   0.274   0.021  -0.260
226   N        -0.830  -0.845  -0.896  -0.658  -0.745  -0.856  -0.902  -0.962  -0.954
227   D        -0.128  -0.241  -0.159  -0.172  -0.381  -0.300  -0.314  -0.513  -0.419
228   L        -0.400  -0.368  -0.175  -0.736  -0.682  -0.376  -0.785  -0.738  -0.447
229   E         0.258   0.087  -0.068   0.326   0.118  -0.114   0.274   0.021  -0.260
230   V        -0.128  -0.068  -0.118  -0.271  -0.178  -0.287  -0.314  -0.222  -0.346
231   G         1.041   1.059   1.138   1.005   1.028   1.161   1.097   1.121   1.238
232   V         0.258   0.206  -0.059   0.337   0.268  -0.151   0.274   0.199  -0.245
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   A        -0.488  -0.701  -0.860  -0.536  -0.829  -1.059  -0.432  -0.707  -0.905
244   T        -0.488  -0.659  -0.850  -0.342  -0.581  -0.925  -0.432  -0.655  -0.892
245   K        -1.569  -1.665  -1.455  -1.637  -1.742  -1.426  -1.490  -1.554  -1.261
246   D        -1.841  -1.694  -1.849  -1.487  -1.298  -1.551  -1.490  -1.341  -1.410
247   K        -0.984  -0.910  -0.901  -1.182  -1.081  -1.034  -1.138  -1.047  -0.962
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   F         1.041   1.059   1.138   1.136   1.158   1.277   1.097   1.121   1.238
250   F        -0.830  -0.702  -0.879  -0.711  -0.535  -0.835  -0.902  -0.741  -0.930
251   T        -1.569  -1.603  -1.450  -1.668  -1.704  -1.482  -1.490  -1.504  -1.257
252   L         1.041   1.059   1.138   1.029   1.055   1.182   1.097   1.121   1.238
253   S        -0.830  -0.780  -0.883  -0.797  -0.770  -0.874  -0.902  -0.865  -0.939
254   A        -1.705  -1.716  -1.472  -1.791  -1.826  -1.487  -1.608  -1.603  -1.277
255   E        -0.334  -0.313  -0.169  -0.575  -0.544  -0.330  -0.667  -0.638  -0.436
256   N         0.258   0.369  -0.045   0.334   0.470  -0.056   0.274   0.426  -0.222
257   I         1.041   1.059   1.138   0.940   0.971   1.104   1.097   1.121   1.238
258   E        -0.400  -0.368  -0.175  -0.690  -0.643  -0.339  -0.785  -0.738  -0.447
259   E         0.258   0.087  -0.068   0.275   0.042  -0.259   0.274   0.021  -0.260
260   R         0.258   0.087  -0.068   0.476   0.275   0.057   0.274   0.021  -0.260
261   L         1.041   1.059   1.138   1.029   1.055   1.182   1.097   1.121   1.238
262   V        -0.830  -0.874  -0.896  -0.785  -0.885  -0.912  -0.902  -0.990  -0.955
263   A        -0.984  -0.905  -0.893  -1.297  -1.206  -1.098  -1.138  -1.062  -0.954
264   I         1.041   1.059   1.138   0.940   0.971   1.104   1.097   1.121   1.238
265   A         1.041   1.059   1.138   0.798   0.823   0.978   1.097   1.121   1.238
266   E         1.041   1.059   1.138   0.976   1.007   1.135   1.097   1.121   1.238
267   Q        -0.128  -0.241  -0.159  -0.089  -0.308  -0.247  -0.314  -0.513  -0.419
268   D         1.041   1.059   1.138   1.055   1.079   1.206   1.097   1.121   1.238
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P21243
Output conservation file - output/P21243
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
