1     M         0.959   0.973   1.040   1.194   1.206   1.286   1.013   1.032   1.127
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     S         0.194   0.085  -0.123   0.295   0.174  -0.125   0.197   0.035  -0.327
6     T        -1.219  -1.096  -1.413  -0.899  -0.759  -1.305  -1.085  -0.951  -1.247
7     S        -1.018  -0.907  -0.924  -1.040  -0.913  -0.842  -1.202  -1.092  -1.005
8     H        -1.589  -1.647  -1.457  -1.250  -1.338  -1.108  -1.551  -1.572  -1.294
9     C         0.959   0.973   1.040   1.236   1.250   1.323   1.013   1.032   1.127
10    R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
11    F         0.194   0.111  -0.123   0.599   0.491   0.124   0.197   0.074  -0.326
12    Y         0.959   0.973   1.040   1.101   1.121   1.205   1.013   1.032   1.127
13    E         0.194   0.085  -0.123   0.052  -0.082  -0.389   0.197   0.035  -0.327
14    N         0.194   0.107  -0.126   0.458   0.331  -0.120   0.197   0.069  -0.331
15    K         0.194   0.111  -0.123   0.176   0.074  -0.256   0.197   0.074  -0.326
16    Y        -0.182  -0.186  -0.202  -0.018  -0.027  -0.085  -0.386  -0.399  -0.464
17    P         0.959   0.973   1.040   1.151   1.160   1.249   1.013   1.032   1.127
18    E         0.194   0.343  -0.106   0.058   0.244  -0.341   0.197   0.400  -0.297
19    I        -0.182  -0.149  -0.198  -0.386  -0.337  -0.441  -0.386  -0.336  -0.457
20    D         0.959   0.973   1.040   0.957   0.980   1.081   1.013   1.032   1.127
21    D        -1.018  -1.052  -0.935  -1.297  -1.333  -1.143  -1.202  -1.219  -1.017
22    I        -1.502  -1.499  -1.463  -1.573  -1.602  -1.465  -1.435  -1.448  -1.299
23    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
24    M         0.194   0.111  -0.123   0.513   0.394  -0.041   0.197   0.074  -0.326
25    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
26    N         0.959   0.973   1.040   1.153   1.164   1.251   1.013   1.032   1.127
27    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
28    Q        -0.868  -1.007  -0.939  -0.715  -0.974  -0.922  -0.968  -1.152  -1.021
29    Q        -0.384  -0.360  -0.220  -0.551  -0.519  -0.358  -0.735  -0.702  -0.496
30    I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
31    A         0.194   0.111  -0.123   0.278   0.183  -0.138   0.197   0.074  -0.326
32    E        -0.182  -0.278  -0.210  -0.473  -0.628  -0.511  -0.386  -0.556  -0.479
33    M         0.959   0.973   1.040   1.194   1.206   1.286   1.013   1.032   1.127
34    G         0.959   0.973   1.040   1.108   1.116   1.211   1.013   1.032   1.127
35    A         0.959   0.973   1.040   0.912   0.934   1.043   1.013   1.032   1.127
36    Y         0.959   0.973   1.040   1.101   1.121   1.205   1.013   1.032   1.127
37    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
38    K         0.194   0.273  -0.115   0.176   0.274  -0.243   0.197   0.306  -0.312
39    L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
40    L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
41    E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
42    Y         0.959   0.973   1.040   1.101   1.121   1.205   1.013   1.032   1.127
43    D         0.959   0.973   1.040   0.957   0.980   1.081   1.013   1.032   1.127
44    N         0.194   0.085  -0.123   0.490   0.341  -0.026   0.197   0.035  -0.327
45    I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
46    E         0.194   0.107  -0.126   0.058  -0.043  -0.374   0.197   0.069  -0.331
47    G         0.959   0.973   1.040   1.108   1.116   1.211   1.013   1.032   1.127
48    M         0.959   0.973   1.040   1.194   1.206   1.286   1.013   1.032   1.127
49    I        -0.448  -0.411  -0.227  -0.864  -0.800  -0.491  -0.852  -0.794  -0.509
50    L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
51    L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
52    S         0.959   0.973   1.040   0.929   0.960   1.057   1.013   1.032   1.127
53    E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
54    L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
55    S         0.959   0.973   1.040   0.929   0.960   1.057   1.013   1.032   1.127
56    R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
57    R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
58    R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
59    I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
60    R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
61    S         0.959   0.973   1.040   0.929   0.960   1.057   1.013   1.032   1.127
62    I         0.194   0.111  -0.123   0.224   0.122  -0.273   0.197   0.074  -0.326
63    Q         0.959   0.973   1.040   1.151   1.174   1.249   1.013   1.032   1.127
64    K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
65    L        -0.182  -0.276  -0.209  -0.256  -0.392  -0.260  -0.386  -0.553  -0.478
66    I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
67    R         0.194   0.085  -0.123   0.342   0.190  -0.179   0.197   0.035  -0.327
68    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
69    G         0.959   0.973   1.040   1.108   1.116   1.211   1.013   1.032   1.127
70    K        -0.182  -0.266  -0.208  -0.346  -0.488  -0.395  -0.386  -0.535  -0.475
71    N         0.959   0.973   1.040   1.153   1.164   1.251   1.013   1.032   1.127
72    D        -0.182   0.006  -0.136  -0.473  -0.182  -0.391  -0.386  -0.087  -0.349
73    V         0.194   0.085  -0.123   0.158   0.015  -0.305   0.197   0.035  -0.327
74    A        -0.448  -0.381  -0.213  -0.859  -0.751  -0.465  -0.852  -0.740  -0.484
75    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
76    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
77    L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
78    R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
79    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
80    D         0.959   0.973   1.040   0.957   0.980   1.081   1.013   1.032   1.127
81    K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
82    E         0.194   0.085  -0.123   0.058  -0.072  -0.370   0.197   0.035  -0.327
83    K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
84    G         0.959   0.973   1.040   1.108   1.116   1.211   1.013   1.032   1.127
85    Y         0.959   0.973   1.040   1.101   1.121   1.205   1.013   1.032   1.127
86    I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
87    D         0.959   0.973   1.040   0.957   0.980   1.081   1.013   1.032   1.127
88    L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
89    S         0.959   0.973   1.040   0.929   0.960   1.057   1.013   1.032   1.127
90    K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
91    R         0.194   0.245  -0.114   0.342   0.402  -0.161   0.197   0.267  -0.310
92    R         0.194   0.245  -0.114   0.342   0.401  -0.161   0.197   0.267  -0.310
93    V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
94    S         0.959   0.973   1.040   0.929   0.960   1.057   1.013   1.032   1.127
95    S        -1.151  -1.073  -0.938  -1.261  -1.132  -0.935  -1.318  -1.224  -1.018
96    E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
97    D         0.959   0.973   1.040   0.957   0.980   1.081   1.013   1.032   1.127
98    I        -0.384  -0.391  -0.227  -0.718  -0.752  -0.489  -0.735  -0.759  -0.509
99    I        -1.018  -1.006  -0.923  -1.335  -1.289  -1.183  -1.202  -1.143  -1.000
100   K         0.194   0.107  -0.126   0.176   0.070  -0.261   0.197   0.069  -0.331
101   C         0.959   0.973   1.040   1.236   1.250   1.323   1.013   1.032   1.127
102   E        -0.182  -0.091  -0.167  -0.473  -0.325  -0.443  -0.386  -0.240  -0.403
103   E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
104   K        -0.384  -0.322  -0.211  -0.612  -0.505  -0.367  -0.735  -0.634  -0.481
105   Y         0.194   0.111  -0.123   0.477   0.380   0.039   0.197   0.074  -0.326
106   Q        -1.018  -1.006  -0.923  -0.842  -0.793  -0.698  -1.202  -1.143  -1.000
107   K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
108   S         0.959   0.973   1.040   0.929   0.960   1.057   1.013   1.032   1.127
109   K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
110   T        -1.018  -1.037  -0.930  -1.104  -1.121  -0.955  -1.202  -1.196  -1.011
111   V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
112   H         0.959   0.973   1.040   1.254   1.263   1.338   1.013   1.032   1.127
113   S         0.959   0.973   1.040   0.929   0.960   1.057   1.013   1.032   1.127
114   I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
115   L        -0.182  -0.266  -0.208  -0.277  -0.403  -0.292  -0.386  -0.535  -0.475
116   R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
117   Y        -0.868  -0.644  -0.886  -0.499  -0.180  -0.570  -0.968  -0.658  -0.951
118   C        -0.868  -1.007  -0.939  -0.655  -0.935  -0.914  -0.968  -1.152  -1.021
119   A         0.959   0.973   1.040   0.912   0.934   1.043   1.013   1.032   1.127
120   E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
121   K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
122   F        -1.502  -1.552  -1.468  -1.023  -1.122  -1.024  -1.435  -1.491  -1.304
123   Q        -2.073  -2.100  -1.885  -1.752  -1.845  -1.577  -1.784  -1.789  -1.479
124   I        -1.018  -1.073  -0.932  -1.238  -1.301  -1.042  -1.202  -1.244  -1.013
125   P        -0.384  -0.354  -0.222  -0.447  -0.407  -0.251  -0.735  -0.690  -0.500
126   L         0.194   0.107  -0.126   0.170   0.061  -0.300   0.197   0.069  -0.331
127   E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
128   E        -2.557  -2.494  -2.221  -2.366  -2.265  -1.932  -2.018  -1.945  -1.591
129   L         0.194   0.111  -0.123   0.213   0.118  -0.176   0.197   0.074  -0.326
130   Y         0.959   0.973   1.040   1.101   1.121   1.205   1.013   1.032   1.127
131   K        -1.589  -1.522  -1.455  -1.805  -1.701  -1.480  -1.551  -1.460  -1.292
132   T        -1.219  -1.173  -1.421  -0.839  -0.787  -1.204  -1.085  -1.036  -1.256
133   I        -0.534  -0.572  -0.875  -0.408  -0.467  -0.918  -0.502  -0.557  -0.936
134   A        -0.384  -0.248  -0.188  -0.493  -0.249  -0.209  -0.735  -0.504  -0.439
135   W         0.959   0.973   1.040   1.294   1.306   1.372   1.013   1.032   1.127
136   P         0.959   0.973   1.040   1.151   1.160   1.249   1.013   1.032   1.127
137   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
138   S        -0.534  -0.697  -0.889  -0.331  -0.525  -0.797  -0.502  -0.713  -0.955
139   R        -0.534  -0.719  -0.893  -0.292  -0.554  -0.864  -0.502  -0.742  -0.959
140   K         0.194   0.299  -0.112   0.176   0.303  -0.238   0.197   0.341  -0.307
141   F        -0.182   0.006  -0.136  -0.018   0.246   0.018  -0.386  -0.087  -0.349
142   G         0.959   0.973   1.040   1.108   1.116   1.211   1.013   1.032   1.127
143   H         0.959   0.973   1.040   1.254   1.263   1.338   1.013   1.032   1.127
144   A         0.194   0.107  -0.126   0.246   0.138  -0.233   0.197   0.069  -0.331
145   Y         0.194   0.107  -0.126   0.422   0.308  -0.117   0.197   0.069  -0.331
146   E        -0.182   0.006  -0.136  -0.318  -0.005  -0.301  -0.386  -0.087  -0.349
147   A         0.194   0.085  -0.123   0.272   0.139  -0.156   0.197   0.035  -0.327
148   F        -0.534  -0.374  -0.862  -0.085   0.110  -0.654  -0.502  -0.299  -0.921
149   K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
150   L        -0.534  -0.425  -0.864  -0.444  -0.308  -0.883  -0.502  -0.362  -0.923
151   S         0.194   0.111  -0.123   0.260   0.164  -0.221   0.197   0.074  -0.326
152   I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
153   I        -1.502  -1.383  -1.441  -1.382  -1.178  -1.365  -1.435  -1.276  -1.276
154   D        -0.384  -0.408  -0.227  -0.499  -0.535  -0.249  -0.735  -0.790  -0.509
155   E        -0.182   0.006  -0.136  -0.128   0.174  -0.144  -0.386  -0.087  -0.349
156   T        -1.589  -1.446  -1.456  -1.478  -1.297  -1.272  -1.551  -1.384  -1.293
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   V         0.194   0.299  -0.112   0.158   0.285  -0.284   0.197   0.341  -0.307
159   W        -0.448  -0.404  -0.225  -0.297  -0.241   0.000  -0.852  -0.781  -0.506
160   E        -1.589  -1.661  -1.466  -1.704  -1.756  -1.415  -1.551  -1.588  -1.303
161   G        -1.018  -0.973  -0.931  -1.026  -0.989  -0.910  -1.202  -1.149  -1.012
162   I        -0.868  -0.906  -0.925  -0.983  -1.083  -1.125  -0.968  -1.042  -1.004
163   E        -0.534  -0.577  -0.876  -0.562  -0.603  -0.985  -0.502  -0.561  -0.939
164   P        -2.424  -2.398  -2.215  -2.002  -1.981  -1.823  -1.901  -1.864  -1.587
165   P         0.194   0.273  -0.115   0.481   0.570  -0.031   0.197   0.306  -0.312
166   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
167   S        -0.534  -0.697  -0.889  -0.385  -0.598  -0.926  -0.502  -0.713  -0.955
168   K        -2.557  -2.482  -2.218  -2.404  -2.319  -1.949  -2.018  -1.936  -1.590
169   D        -1.502  -1.550  -1.468  -1.492  -1.589  -1.481  -1.435  -1.490  -1.305
170   V        -0.384  -0.343  -0.218  -0.746  -0.680  -0.478  -0.735  -0.672  -0.494
171   L        -1.854  -1.992  -1.880  -1.629  -1.834  -1.625  -1.551  -1.677  -1.474
172   D        -1.502  -1.311  -1.445  -1.529  -1.288  -1.361  -1.435  -1.232  -1.282
173   E        -0.182  -0.276  -0.209  -0.473  -0.626  -0.510  -0.386  -0.553  -0.478
174   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
175   K         0.194   0.111  -0.123   0.149   0.041  -0.330   0.197   0.074  -0.326
176   N        -2.206  -2.048  -1.883  -2.103  -1.927  -1.606  -1.901  -1.757  -1.478
177   Y        -0.384  -0.391  -0.227  -0.376  -0.395  -0.166  -0.735  -0.759  -0.509
178   I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
179   S        -0.534  -0.572  -0.875  -0.339  -0.384  -0.795  -0.502  -0.557  -0.936
180   K        -0.384  -0.314  -0.211  -0.612  -0.488  -0.366  -0.735  -0.619  -0.480
181   R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
182   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
183   T         0.959   0.973   1.040   1.098   1.106   1.204   1.013   1.032   1.127
184   P         0.959   0.973   1.040   1.151   1.160   1.249   1.013   1.032   1.127
185   Q         0.194   0.085  -0.123   0.515   0.385   0.047   0.197   0.035  -0.327
186   A        -0.384  -0.408  -0.227  -0.538  -0.572  -0.277  -0.735  -0.790  -0.509
187   V        -1.018  -1.052  -0.935  -1.254  -1.280  -1.047  -1.202  -1.219  -1.017
188   K         0.194   0.245  -0.114   0.195   0.259  -0.189   0.197   0.267  -0.310
189   I        -0.182  -0.278  -0.210  -0.336  -0.514  -0.450  -0.386  -0.556  -0.479
190   R         0.959   0.973   1.040   1.022   1.036   1.138   1.013   1.032   1.127
191   A         0.959   0.973   1.040   0.912   0.934   1.043   1.013   1.032   1.127
192   D         0.959   0.973   1.040   0.957   0.980   1.081   1.013   1.032   1.127
193   V         0.194   0.085  -0.123   0.158   0.015  -0.305   0.197   0.035  -0.327
194   E        -0.182  -0.214  -0.204  -0.473  -0.522  -0.501  -0.386  -0.447  -0.467
195   V         0.194   0.085  -0.123   0.158   0.015  -0.305   0.197   0.035  -0.327
196   S        -0.384  -0.408  -0.227  -0.552  -0.591  -0.301  -0.735  -0.790  -0.509
197   C         0.959   0.973   1.040   1.236   1.250   1.323   1.013   1.032   1.127
198   F         0.959   0.973   1.040   1.230   1.241   1.317   1.013   1.032   1.127
199   S        -0.868  -1.018  -0.940  -0.841  -1.061  -0.953  -0.968  -1.161  -1.021
200   Y         0.959   0.973   1.040   1.101   1.121   1.205   1.013   1.032   1.127
201   E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
202   G         0.959   0.973   1.040   1.108   1.116   1.211   1.013   1.032   1.127
203   I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
204   D        -0.534  -0.716  -0.888  -0.365  -0.617  -0.922  -0.502  -0.738  -0.954
205   A         0.959   0.973   1.040   0.912   0.934   1.043   1.013   1.032   1.127
206   I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
207   K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
208   D        -2.073  -2.059  -1.877  -2.242  -2.220  -1.887  -1.784  -1.759  -1.473
209   A         0.959   0.973   1.040   0.912   0.934   1.043   1.013   1.032   1.127
210   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
211   K        -1.219  -1.306  -1.437  -1.096  -1.236  -1.393  -1.085  -1.187  -1.272
212   S        -1.018  -0.990  -0.922  -1.170  -1.075  -0.958  -1.202  -1.124  -0.999
213   A         0.194   0.085  -0.123   0.272   0.139  -0.156   0.197   0.035  -0.327
214   E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
215   D        -2.073  -2.097  -1.879  -2.103  -2.110  -1.817  -1.784  -1.777  -1.474
216   M        -2.206  -2.126  -1.882  -2.195  -2.130  -1.755  -1.901  -1.810  -1.477
217   S        -0.868  -1.007  -0.939  -0.758  -0.938  -0.794  -0.968  -1.152  -1.021
218   T         0.194   0.085  -0.123   0.432   0.280  -0.080   0.197   0.035  -0.327
219   E         0.194   0.245  -0.114   0.054   0.128  -0.365   0.197   0.267  -0.310
220   Q        -0.868  -1.018  -0.940  -0.786  -1.079  -1.051  -0.968  -1.161  -1.021
221   M        -0.868  -1.009  -0.939  -0.660  -0.932  -0.866  -0.968  -1.153  -1.021
222   Q        -0.868  -0.863  -0.923  -0.618  -0.650  -0.766  -0.968  -0.998  -1.002
223   V        -0.384  -0.335  -0.217  -0.746  -0.664  -0.475  -0.735  -0.657  -0.491
224   K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
225   V        -0.868  -0.869  -0.910  -0.948  -0.920  -0.946  -0.968  -0.947  -0.983
226   K         0.194   0.107  -0.126   0.176   0.070  -0.261   0.197   0.069  -0.331
227   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
228   V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
229   A         0.194   0.107  -0.126   0.246   0.138  -0.233   0.197   0.069  -0.331
230   A        -0.182  -0.266  -0.208  -0.223  -0.356  -0.266  -0.386  -0.535  -0.475
231   P         0.959   0.973   1.040   1.151   1.160   1.249   1.013   1.032   1.127
232   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
233   Y         0.194   0.085  -0.123   0.477   0.349   0.038   0.197   0.035  -0.327
234   V         0.194   0.245  -0.114   0.207   0.264  -0.158   0.197   0.267  -0.310
235   L        -0.384  -0.302  -0.207  -0.735  -0.588  -0.449  -0.735  -0.599  -0.474
236   T        -0.534  -0.525  -0.871  -0.242  -0.254  -0.831  -0.502  -0.498  -0.932
237   T        -1.502  -1.581  -1.461  -1.343  -1.449  -1.317  -1.435  -1.491  -1.297
238   Q        -0.868  -1.007  -0.939  -0.594  -0.815  -0.732  -0.968  -1.152  -1.021
239   A        -0.868  -0.885  -0.927  -0.803  -0.836  -0.872  -0.968  -1.021  -1.006
240   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
241   D         0.959   0.973   1.040   0.957   0.980   1.081   1.013   1.032   1.127
242   K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
243   Q        -1.589  -1.561  -1.461  -1.352  -1.316  -1.213  -1.551  -1.505  -1.298
244   K        -2.557  -2.496  -2.218  -2.538  -2.480  -2.118  -2.018  -1.946  -1.589
245   G         0.194   0.085  -0.123   0.439   0.285  -0.079   0.197   0.035  -0.327
246   I        -0.868  -0.878  -0.914  -0.985  -0.981  -1.103  -0.968  -0.962  -0.990
247   E        -2.206  -2.065  -1.882  -2.319  -2.124  -1.834  -1.901  -1.774  -1.477
248   Q        -1.854  -1.939  -1.873  -1.665  -1.821  -1.676  -1.551  -1.633  -1.469
249   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
250   E        -0.868  -0.931  -0.922  -0.989  -1.055  -0.971  -0.968  -1.037  -1.001
251   S        -1.589  -1.392  -1.454  -1.864  -1.604  -1.574  -1.551  -1.346  -1.291
252   A         0.959   0.973   1.040   0.912   0.934   1.043   1.013   1.032   1.127
253   I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
254   E        -1.854  -1.824  -1.856  -1.775  -1.722  -1.722  -1.551  -1.520  -1.455
255   K        -0.534  -0.697  -0.889  -0.496  -0.717  -1.024  -0.502  -0.713  -0.955
256   I        -0.534  -0.529  -0.874  -0.392  -0.372  -0.880  -0.502  -0.502  -0.936
257   T        -2.206  -2.038  -1.884  -2.160  -1.967  -1.689  -1.901  -1.749  -1.478
258   E        -0.534  -0.697  -0.889  -0.593  -0.808  -1.078  -0.502  -0.713  -0.955
259   V        -0.384  -0.248  -0.188  -0.697  -0.433  -0.384  -0.735  -0.504  -0.439
260   I         0.959   0.973   1.040   0.905   0.934   1.037   1.013   1.032   1.127
261   T        -1.502  -1.316  -1.445  -1.637  -1.387  -1.519  -1.435  -1.235  -1.282
262   K        -1.018  -0.841  -0.912  -1.220  -0.933  -0.968  -1.202  -0.963  -0.986
263   Y        -1.018  -0.990  -0.922  -1.088  -1.016  -0.936  -1.202  -1.124  -0.999
264   G        -0.182  -0.186  -0.202  -0.036  -0.059  -0.119  -0.386  -0.399  -0.464
265   G         0.959   0.973   1.040   1.108   1.116   1.211   1.013   1.032   1.127
266   V        -2.424  -2.475  -2.228  -2.142  -2.196  -1.820  -1.901  -1.924  -1.596
267   C        -0.182  -0.278  -0.210  -0.009  -0.211  -0.204  -0.386  -0.556  -0.479
268   N        -1.721  -1.725  -1.482  -1.671  -1.696  -1.379  -1.668  -1.647  -1.317
269   I        -0.182   0.006  -0.136  -0.386  -0.098  -0.328  -0.386  -0.087  -0.349
270   T        -1.018  -0.969  -0.934  -1.111  -1.098  -1.003  -1.202  -1.143  -1.015
271   M         0.959   0.973   1.040   1.194   1.206   1.286   1.013   1.032   1.127
272   P        -2.073  -2.020  -1.882  -2.010  -2.032  -1.834  -1.784  -1.728  -1.476
273   P         0.959   0.973   1.040   1.151   1.160   1.249   1.013   1.032   1.127
274   K         0.959   0.973   1.040   0.829   0.851   0.971   1.013   1.032   1.127
275   A         0.959   0.973   1.040   0.912   0.934   1.043   1.013   1.032   1.127
276   V         0.959   0.973   1.040   0.829   0.845   0.971   1.013   1.032   1.127
277   T        -0.182  -0.200  -0.201  -0.116  -0.162  -0.237  -0.386  -0.422  -0.463
278   A        -0.384  -0.408  -0.227  -0.769  -0.861  -0.557  -0.735  -0.790  -0.509
279   T        -0.534  -0.577  -0.876  -0.192  -0.267  -0.723  -0.502  -0.561  -0.939
280   E        -0.384  -0.408  -0.227  -0.813  -0.841  -0.521  -0.735  -0.790  -0.509
281   D         0.194   0.111  -0.123   0.262   0.151  -0.273   0.197   0.074  -0.326
282   A         0.194   0.111  -0.123   0.233   0.125  -0.263   0.197   0.074  -0.326
283   E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
284   L         0.959   0.973   1.040   0.841   0.861   0.981   1.013   1.032   1.127
285   Q        -0.868  -0.906  -0.925  -0.739  -0.846  -0.960  -0.968  -1.042  -1.004
286   A        -1.219  -1.346  -1.436  -1.058  -1.257  -1.425  -1.085  -1.227  -1.271
287   L         0.194   0.245  -0.114   0.213   0.276  -0.163   0.197   0.267  -0.310
288   L        -0.384  -0.408  -0.227  -0.577  -0.593  -0.292  -0.735  -0.790  -0.509
289   E        -0.534  -0.574  -0.875  -0.584  -0.639  -1.034  -0.502  -0.557  -0.936
290   S        -1.237  -1.124  -0.950  -1.531  -1.358  -1.081  -1.435  -1.283  -1.033
291   K        -1.502  -1.634  -1.468  -1.443  -1.599  -1.298  -1.435  -1.556  -1.304
292   E         0.959   0.973   1.040   0.721   0.749   0.878   1.013   1.032   1.127
293   L        -2.206  -2.200  -1.888  -2.195  -2.161  -1.733  -1.901  -1.861  -1.481
294   D        -0.868  -0.807  -0.889  -1.050  -0.915  -1.004  -0.968  -0.859  -0.955
295   N        -0.868  -0.729  -0.899  -0.651  -0.457  -0.736  -0.968  -0.783  -0.969
296   R        -1.237  -1.207  -0.963  -1.517  -1.492  -1.105  -1.435  -1.387  -1.048
297   S        -1.589  -1.572  -1.457  -1.847  -1.822  -1.620  -1.551  -1.505  -1.293
298   D        -1.721  -1.723  -1.483  -1.895  -1.913  -1.554  -1.668  -1.646  -1.317
299   S         0.194   0.085  -0.123   0.266   0.138  -0.204   0.197   0.035  -0.327
300   E        -1.237  -1.124  -0.950  -1.507  -1.265  -1.033  -1.435  -1.283  -1.033
301   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   D        -0.182  -0.091  -0.167  -0.318  -0.162  -0.368  -0.386  -0.240  -0.403
303   E         0.194   0.085  -0.123   0.058  -0.072  -0.370   0.197   0.035  -0.327
304   D        -0.868  -0.935  -0.924  -0.958  -1.057  -1.109  -0.968  -1.043  -1.002
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   E        -2.307  -2.216  -1.902  -2.288  -2.140  -1.720  -1.971  -1.873  -1.491
313   S        -0.802  -0.921  -0.925  -0.654  -0.820  -0.834  -0.852  -1.009  -1.001
314   D        -0.802  -0.907  -0.923  -0.764  -0.935  -1.015  -0.852  -0.991  -0.998
315   D        -2.557  -2.556  -2.225  -2.279  -2.245  -1.848  -2.018  -1.984  -1.594
316   E        -1.219  -1.179  -1.426  -1.274  -1.228  -1.593  -1.085  -1.039  -1.261
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P20459
Output conservation file - output/P20459
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
