1     M         1.284   1.305   1.383   1.509   1.539   1.648   1.384   1.414   1.531
2     S        -0.492  -0.545  -0.432  -0.616  -0.691  -0.526  -0.720  -0.780  -0.622
3     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    S        -0.385  -0.329  -0.395  -0.420  -0.331  -0.482  -0.544  -0.466  -0.567
12    L        -0.898  -0.843  -0.891  -1.123  -1.047  -1.079  -0.912  -0.843  -0.877
13    T        -1.785  -1.740  -1.620  -1.669  -1.626  -1.474  -1.427  -1.382  -1.208
14    L         0.233   0.253   0.259  -0.154  -0.126  -0.104  -0.021   0.006  -0.030
15    L        -0.742  -0.766  -0.874  -0.966  -1.009  -1.151  -0.724  -0.750  -0.857
16    K        -0.394  -0.449  -0.414  -0.366  -0.447  -0.396  -0.584  -0.657  -0.600
17    E        -1.090  -1.032  -0.933  -1.230  -1.163  -0.985  -1.146  -1.082  -0.926
18    K         0.564   0.527   0.370   0.659   0.613   0.360   0.541   0.479   0.177
19    H         1.284   1.305   1.383   1.460   1.491   1.601   1.384   1.414   1.531
20    I         0.085   0.097   0.213  -0.136  -0.121   0.053  -0.303  -0.289  -0.120
21    R        -1.785  -1.724  -1.620  -1.620  -1.548  -1.399  -1.427  -1.369  -1.208
22    Y         1.284   1.305   1.383   1.413   1.449   1.556   1.384   1.414   1.531
23    I         0.564   0.439   0.364   0.595   0.399   0.219   0.541   0.334   0.167
24    E        -1.438  -1.439  -1.309  -1.275  -1.254  -1.090  -1.287  -1.275  -1.093
25    S        -0.394  -0.440  -0.416  -0.534  -0.622  -0.589  -0.584  -0.651  -0.602
26    L        -0.114  -0.249  -0.344  -0.305  -0.494  -0.602  -0.162  -0.353  -0.494
27    D        -0.114  -0.249  -0.344  -0.100  -0.312  -0.476  -0.162  -0.353  -0.494
28    T        -0.959  -0.936  -0.901  -0.944  -0.894  -0.843  -1.005  -0.965  -0.890
29    K        -0.959  -0.885  -0.891  -0.831  -0.695  -0.728  -1.005  -0.903  -0.879
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    K         0.493   0.380   0.333   0.581   0.420   0.326   0.428   0.233   0.110
33    H        -1.306  -1.172  -1.262  -1.140  -0.968  -1.062  -1.146  -1.001  -1.049
34    N        -1.438  -1.350  -1.305  -1.413  -1.286  -1.203  -1.287  -1.196  -1.089
35    F        -0.611  -0.607  -0.469  -0.850  -0.871  -0.671  -0.865  -0.858  -0.669
36    E         0.233   0.161   0.233   0.118  -0.031   0.049  -0.021  -0.166  -0.080
37    Y         0.564   0.439   0.364   0.768   0.603   0.459   0.541   0.334   0.167
38    W         1.284   1.305   1.383   1.466   1.498   1.607   1.384   1.414   1.531
39    L         1.284   1.305   1.383   0.963   0.994   1.130   1.384   1.414   1.531
40    T        -0.959  -0.992  -0.907  -1.074  -1.117  -1.029  -1.005  -1.031  -0.898
41    E         1.284   1.305   1.383   1.308   1.347   1.457   1.384   1.414   1.531
42    H         1.284   1.305   1.383   1.460   1.491   1.601   1.384   1.414   1.531
43    L         1.284   1.305   1.383   0.963   0.994   1.130   1.384   1.414   1.531
44    R         0.564   0.439   0.364   0.784   0.623   0.496   0.541   0.334   0.167
45    L        -0.394  -0.482  -0.415  -0.649  -0.764  -0.623  -0.584  -0.689  -0.598
46    N         0.564   0.439   0.364   0.768   0.592   0.436   0.541   0.334   0.167
47    G         0.564   0.439   0.364   0.543   0.366   0.245   0.541   0.334   0.167
48    I        -0.611  -0.568  -0.457  -1.050  -0.992  -0.794  -0.865  -0.805  -0.653
49    Y         1.284   1.305   1.383   1.413   1.449   1.556   1.384   1.414   1.531
50    W         1.284   1.305   1.383   1.466   1.498   1.607   1.384   1.414   1.531
51    G         0.564   0.439   0.364   0.533   0.353   0.223   0.541   0.334   0.167
52    L        -0.394  -0.482  -0.415  -0.714  -0.815  -0.678  -0.584  -0.689  -0.598
53    T         0.564   0.439   0.364   0.748   0.592   0.474   0.541   0.334   0.167
54    A         0.564   0.439   0.364   0.640   0.462   0.320   0.541   0.334   0.167
55    L         0.564   0.439   0.364   0.320   0.154   0.057   0.541   0.334   0.167
56    C        -1.785  -1.797  -1.634  -1.418  -1.436  -1.236  -1.427  -1.424  -1.218
57    V        -0.959  -0.859  -0.891  -1.240  -1.110  -1.098  -1.005  -0.887  -0.881
58    L         0.122   0.132   0.221  -0.242  -0.189  -0.049  -0.230  -0.220  -0.106
59    D        -1.340  -1.410  -1.303  -1.253  -1.360  -1.177  -1.199  -1.248  -1.088
60    S        -1.644  -1.720  -1.617  -1.524  -1.612  -1.530  -1.306  -1.360  -1.205
61    P        -1.455  -1.422  -1.305  -1.515  -1.464  -1.265  -1.306  -1.267  -1.091
62    E        -0.846  -0.838  -0.882  -0.840  -0.837  -0.923  -0.876  -0.870  -0.872
63    T        -0.846  -0.791  -0.863  -0.763  -0.686  -0.781  -0.876  -0.793  -0.848
64    F        -0.427  -0.433  -0.393  -0.768  -0.750  -0.679  -0.661  -0.638  -0.570
65    V        -1.759  -1.678  -1.609  -1.590  -1.524  -1.387  -1.414  -1.341  -1.201
66    K        -0.427  -0.437  -0.407  -0.429  -0.431  -0.366  -0.661  -0.668  -0.594
67    E        -0.846  -0.860  -0.878  -0.812  -0.812  -0.866  -0.876  -0.875  -0.867
68    E        -0.921  -0.940  -0.887  -1.006  -1.030  -0.935  -0.983  -0.989  -0.879
69    V        -0.008  -0.123  -0.311   0.160   0.001  -0.282  -0.015  -0.173  -0.447
70    I         0.122   0.135   0.220  -0.061  -0.055   0.067  -0.230  -0.215  -0.107
71    S        -1.150  -1.125  -0.958  -1.269  -1.251  -0.991  -1.199  -1.163  -0.948
72    F         0.622   0.609   0.398   0.804   0.787   0.496   0.631   0.609   0.229
73    V        -0.008  -0.106  -0.305   0.093  -0.057  -0.417  -0.015  -0.150  -0.439
74    L         0.622   0.609   0.398   0.415   0.443   0.164   0.631   0.609   0.229
75    S        -0.008  -0.042  -0.297   0.079   0.044  -0.386  -0.015  -0.060  -0.427
76    C         1.284   1.305   1.383   1.460   1.482   1.602   1.384   1.414   1.531
77    W         1.284   1.305   1.383   1.472   1.506   1.613   1.384   1.414   1.531
78    D        -0.297  -0.388  -0.394  -0.402  -0.564  -0.597  -0.445  -0.565  -0.571
79    D        -1.455  -1.470  -1.307  -1.386  -1.396  -1.163  -1.306  -1.301  -1.093
80    K        -0.846  -0.851  -0.887  -0.727  -0.744  -0.772  -0.876  -0.891  -0.878
81    Y        -1.340  -1.310  -1.285  -1.081  -1.052  -1.003  -1.199  -1.169  -1.073
82    G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
83    A         0.296   0.358   0.283   0.141   0.199   0.090   0.093   0.195   0.015
84    F         1.284   1.305   1.383   1.366   1.387   1.512   1.384   1.414   1.531
85    A         0.067   0.091   0.215  -0.264  -0.272  -0.033  -0.338  -0.301  -0.117
86    P        -0.846  -0.854  -0.861  -0.726  -0.749  -0.735  -0.876  -0.860  -0.846
87    F        -0.542  -0.572  -0.459  -0.561  -0.626  -0.462  -0.768  -0.809  -0.655
88    P         1.284   1.305   1.383   1.432   1.446   1.574   1.384   1.414   1.531
89    R        -1.036  -1.050  -0.935  -1.026  -1.087  -0.890  -1.091  -1.097  -0.927
90    H         1.284   1.305   1.383   1.458   1.513   1.600   1.384   1.414   1.531
91    D         1.284   1.305   1.383   1.201   1.213   1.356   1.384   1.414   1.531
92    A        -0.297  -0.349  -0.376  -0.362  -0.478  -0.529  -0.445  -0.504  -0.546
93    H         1.284   1.305   1.383   1.458   1.513   1.600   1.384   1.414   1.531
94    L        -0.427  -0.401  -0.389  -0.692  -0.571  -0.551  -0.661  -0.600  -0.565
95    L         0.296   0.251   0.260  -0.051  -0.085  -0.093   0.093   0.002  -0.028
96    T        -0.921  -0.957  -0.898  -0.871  -0.904  -0.803  -0.983  -1.000  -0.889
97    T         1.284   1.305   1.383   1.375   1.416   1.521   1.384   1.414   1.531
98    L         0.296   0.237   0.253  -0.078  -0.147  -0.148   0.093  -0.022  -0.042
99    S         0.622   0.546   0.393   0.700   0.623   0.394   0.631   0.511   0.219
100   A         0.296   0.378   0.303   0.202   0.304   0.167   0.093   0.230   0.053
101   V        -0.427  -0.382  -0.400  -0.742  -0.648  -0.680  -0.661  -0.596  -0.584
102   Q         1.284   1.305   1.383   1.410   1.441   1.554   1.384   1.414   1.531
103   I         0.296   0.247   0.250   0.253   0.155   0.128   0.093  -0.005  -0.048
104   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
105   A        -0.601  -0.585  -0.814  -0.485  -0.484  -0.872  -0.553  -0.530  -0.789
106   T        -1.036  -1.033  -0.933  -0.937  -0.928  -0.791  -1.091  -1.085  -0.925
107   Y        -0.601  -0.721  -0.849  -0.349  -0.505  -0.825  -0.553  -0.694  -0.829
108   D         0.622   0.693   0.405   0.641   0.709   0.361   0.631   0.734   0.241
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   A        -0.427  -0.434  -0.402  -0.542  -0.565  -0.470  -0.661  -0.662  -0.588
118   L        -0.008  -0.067  -0.302  -0.153  -0.191  -0.513  -0.015  -0.095  -0.434
119   D        -0.427  -0.468  -0.407  -0.573  -0.608  -0.491  -0.661  -0.695  -0.593
120   V        -1.759  -1.756  -1.612  -1.641  -1.660  -1.437  -1.414  -1.396  -1.203
121   L        -0.008  -0.099  -0.307  -0.189  -0.276  -0.598  -0.015  -0.140  -0.442
122   G        -1.455  -1.419  -1.311  -1.460  -1.430  -1.236  -1.306  -1.262  -1.095
123   K        -1.759  -1.767  -1.616  -1.667  -1.677  -1.465  -1.414  -1.403  -1.206
124   D        -1.340  -1.333  -1.280  -1.240  -1.225  -1.109  -1.199  -1.174  -1.067
125   R        -0.898  -0.859  -0.900  -0.799  -0.771  -0.829  -0.912  -0.868  -0.886
126   K        -0.492  -0.385  -0.420  -0.476  -0.301  -0.369  -0.720  -0.568  -0.603
127   V        -1.051  -0.961  -0.926  -1.219  -1.100  -1.036  -1.103  -1.007  -0.917
128   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
129   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
130   R        -0.542  -0.512  -0.445  -0.516  -0.473  -0.401  -0.768  -0.726  -0.636
131   L        -0.846  -0.851  -0.887  -1.072  -1.069  -1.054  -0.876  -0.891  -0.878
132   I        -1.340  -1.309  -1.284  -1.261  -1.258  -1.186  -1.199  -1.168  -1.073
133   S        -1.036  -1.012  -0.919  -1.126  -1.075  -0.966  -1.091  -1.053  -0.911
134   F         0.122   0.105   0.217   0.060   0.031   0.186  -0.230  -0.272  -0.113
135   I         1.284   1.305   1.383   1.303   1.332   1.452   1.384   1.414   1.531
136   R        -1.759  -1.775  -1.614  -1.652  -1.676  -1.479  -1.414  -1.409  -1.205
137   G         0.067   0.088   0.213  -0.282  -0.271  -0.052  -0.338  -0.307  -0.121
138   N         0.122   0.210   0.260  -0.286  -0.129  -0.064  -0.230  -0.072  -0.030
139   Q         0.622   0.617   0.401   0.853   0.855   0.553   0.631   0.621   0.234
140   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   L        -1.150  -1.215  -1.260  -1.178  -1.219  -1.248  -0.983  -1.046  -1.048
142   E        -1.340  -1.306  -1.275  -1.182  -1.135  -1.098  -1.199  -1.156  -1.065
143   D        -0.297  -0.297  -0.376  -0.327  -0.355  -0.421  -0.445  -0.455  -0.546
144   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
145   S        -0.601  -0.631  -0.825  -0.397  -0.426  -0.707  -0.553  -0.584  -0.801
146   F        -0.008  -0.099  -0.307   0.249   0.126  -0.175  -0.015  -0.140  -0.442
147   Q        -0.601  -0.721  -0.849  -0.307  -0.488  -0.731  -0.553  -0.694  -0.829
148   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
149   D         1.284   1.305   1.383   1.201   1.213   1.356   1.384   1.414   1.531
150   R        -1.036  -1.033  -0.926  -1.023  -1.000  -0.873  -1.091  -1.077  -0.918
151   F        -0.542  -0.583  -0.466  -0.485  -0.537  -0.381  -0.768  -0.825  -0.664
152   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
153   E         1.284   1.305   1.383   1.311   1.367   1.460   1.384   1.414   1.531
154   V        -0.601  -0.687  -0.835  -0.393  -0.519  -0.750  -0.553  -0.654  -0.813
155   D         1.284   1.305   1.383   1.201   1.213   1.356   1.384   1.414   1.531
156   T        -0.008  -0.026  -0.293   0.216   0.194  -0.231  -0.015  -0.044  -0.422
157   R         1.284   1.305   1.383   1.412   1.449   1.556   1.384   1.414   1.531
158   F         1.284   1.305   1.383   1.366   1.387   1.512   1.384   1.414   1.531
159   V         0.122   0.105   0.217  -0.241  -0.303  -0.157  -0.230  -0.272  -0.113
160   Y         1.284   1.305   1.383   1.422   1.485   1.565   1.384   1.414   1.531
161   T        -0.601  -0.721  -0.849  -0.362  -0.542  -0.797  -0.553  -0.694  -0.829
162   A         0.622   0.546   0.393   0.691   0.563   0.336   0.631   0.511   0.219
163   L        -0.846  -0.911  -0.891  -1.096  -1.156  -1.093  -0.876  -0.944  -0.882
164   S        -0.427  -0.410  -0.410  -0.461  -0.434  -0.394  -0.661  -0.644  -0.597
165   A        -0.616  -0.589  -0.464  -0.718  -0.691  -0.500  -0.876  -0.837  -0.662
166   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
167   S         0.296   0.272   0.254   0.209   0.160   0.095   0.093   0.041  -0.040
168   I         0.296   0.269   0.257   0.148   0.092  -0.031   0.093   0.037  -0.035
169   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
170   G        -0.008   0.027  -0.289   0.091   0.108  -0.266  -0.015   0.033  -0.416
171   E        -1.340  -1.305  -1.270  -1.308  -1.241  -1.234  -1.199  -1.147  -1.060
172   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
173   T        -0.846  -0.862  -0.888  -0.748  -0.794  -0.831  -0.876  -0.900  -0.878
174   S        -2.368  -2.327  -2.128  -2.162  -2.074  -1.836  -1.629  -1.588  -1.362
175   E        -0.846  -0.921  -0.897  -0.951  -1.073  -1.089  -0.876  -0.958  -0.887
176   V        -1.036  -1.056  -0.929  -1.057  -1.099  -0.907  -1.091  -1.101  -0.922
177   V        -0.601  -0.672  -0.841  -0.410  -0.525  -0.792  -0.553  -0.636  -0.820
178   D        -0.427  -0.462  -0.400  -0.580  -0.613  -0.494  -0.661  -0.684  -0.584
179   P        -0.846  -0.917  -0.894  -0.649  -0.784  -0.755  -0.876  -0.955  -0.885
180   A         0.622   0.617   0.401   0.736   0.715   0.457   0.631   0.621   0.234
181   V        -0.008  -0.042  -0.297   0.138   0.083  -0.305  -0.015  -0.060  -0.427
182   D        -1.644  -1.586  -1.583  -1.469  -1.419  -1.378  -1.306  -1.243  -1.179
183   F        -0.846  -0.866  -0.890  -0.605  -0.631  -0.646  -0.876  -0.904  -0.880
184   V        -0.008   0.026  -0.284   0.098   0.123  -0.374  -0.015   0.022  -0.409
185   L        -1.036  -0.956  -0.914  -1.111  -0.950  -0.935  -1.091  -1.002  -0.905
186   K        -1.036  -1.024  -0.918  -1.009  -1.003  -0.827  -1.091  -1.067  -0.909
187   C         1.284   1.305   1.383   1.460   1.482   1.602   1.384   1.414   1.531
188   Y        -1.150  -1.196  -1.259  -0.789  -0.836  -0.991  -0.983  -1.023  -1.046
189   N         1.284   1.305   1.383   1.430   1.459   1.573   1.384   1.414   1.531
190   F         0.622   0.617   0.401   0.741   0.729   0.353   0.631   0.621   0.234
191   D         1.284   1.305   1.383   1.201   1.213   1.356   1.384   1.414   1.531
192   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
193   G         0.622   0.661   0.401   0.610   0.628   0.296   0.631   0.687   0.233
194   F         0.622   0.590   0.395   0.804   0.763   0.492   0.631   0.579   0.223
195   G         0.622   0.698   0.408   0.636   0.697   0.368   0.631   0.742   0.246
196   L        -0.427  -0.437  -0.398  -0.674  -0.652  -0.575  -0.661  -0.659  -0.582
197   C        -1.759  -1.734  -1.609  -1.620  -1.587  -1.432  -1.414  -1.380  -1.201
198   P         1.284   1.305   1.383   1.432   1.446   1.574   1.384   1.414   1.531
199   N        -0.008   0.163  -0.268   0.066   0.248  -0.285  -0.015   0.216  -0.386
200   A         0.622   0.609   0.398   0.701   0.666   0.370   0.631   0.609   0.229
201   E         1.284   1.305   1.383   1.311   1.367   1.460   1.384   1.414   1.531
202   S         1.284   1.305   1.383   1.261   1.300   1.413   1.384   1.414   1.531
203   H         1.284   1.305   1.383   1.458   1.513   1.600   1.384   1.414   1.531
204   A        -0.008  -0.123  -0.311   0.111  -0.080  -0.373  -0.015  -0.173  -0.447
205   A         0.622   0.590   0.395   0.691   0.623   0.341   0.631   0.579   0.223
206   Q         0.622   0.546   0.393   0.860   0.773   0.556   0.631   0.511   0.219
207   A        -0.427  -0.454  -0.408  -0.546  -0.610  -0.500  -0.661  -0.687  -0.595
208   F         1.284   1.305   1.383   1.366   1.387   1.512   1.384   1.414   1.531
209   T         0.622   0.698   0.408   0.819   0.921   0.533   0.631   0.742   0.246
210   C         1.284   1.305   1.383   1.460   1.482   1.602   1.384   1.414   1.531
211   L        -0.616  -0.577  -0.460  -1.032  -0.923  -0.757  -0.876  -0.819  -0.657
212   G         0.122   0.118   0.217  -0.166  -0.224  -0.029  -0.230  -0.248  -0.112
213   A         0.622   0.661   0.401   0.717   0.748   0.412   0.631   0.687   0.233
214   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
215   A        -0.297  -0.388  -0.394  -0.271  -0.420  -0.424  -0.445  -0.565  -0.571
216   I         1.284   1.305   1.383   1.303   1.332   1.452   1.384   1.414   1.531
217   A        -1.340  -1.356  -1.284  -1.288  -1.332  -1.213  -1.199  -1.196  -1.071
218   N         0.067   0.088   0.213  -0.156  -0.148   0.072  -0.338  -0.307  -0.121
219   K        -0.297  -0.263  -0.372  -0.239  -0.182  -0.365  -0.445  -0.399  -0.541
220   L         0.622   0.590   0.395   0.385   0.386   0.088   0.631   0.579   0.223
221   D        -0.601  -0.564  -0.815  -0.445  -0.412  -0.722  -0.553  -0.505  -0.790
222   M        -0.601  -0.397  -0.796  -0.710  -0.416  -0.943  -0.553  -0.300  -0.767
223   L        -0.921  -0.849  -0.891  -1.172  -1.032  -1.067  -0.983  -0.902  -0.883
224   S        -0.846  -0.686  -0.855  -0.833  -0.627  -0.826  -0.876  -0.682  -0.839
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   L        -2.368  -2.327  -2.128  -2.318  -2.230  -1.985  -1.629  -1.588  -1.362
230   E        -0.542  -0.553  -0.452  -0.697  -0.724  -0.597  -0.768  -0.782  -0.645
231   E        -1.455  -1.420  -1.311  -1.551  -1.492  -1.312  -1.306  -1.263  -1.095
232   I        -0.427  -0.381  -0.386  -0.815  -0.722  -0.715  -0.661  -0.576  -0.560
233   G        -0.601  -0.589  -0.814  -0.485  -0.506  -0.783  -0.553  -0.535  -0.789
234   W        -1.150  -1.143  -1.248  -0.753  -0.740  -0.950  -0.983  -0.969  -1.035
235   W         1.284   1.305   1.383   1.468   1.517   1.609   1.384   1.414   1.531
236   L         0.622   0.546   0.393   0.383   0.325   0.079   0.631   0.511   0.219
237   C        -0.297  -0.221  -0.341  -0.249  -0.126  -0.300  -0.445  -0.320  -0.493
238   E         1.284   1.305   1.383   1.311   1.367   1.460   1.384   1.414   1.531
239   R         1.284   1.305   1.383   1.412   1.449   1.556   1.384   1.414   1.531
240   Q         1.284   1.305   1.383   1.410   1.441   1.554   1.384   1.414   1.531
241   L        -0.542  -0.492  -0.441  -0.808  -0.709  -0.699  -0.768  -0.696  -0.631
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   P        -0.008  -0.123  -0.311   0.280   0.103  -0.196  -0.015  -0.173  -0.447
244   E        -0.542  -0.572  -0.458  -0.717  -0.786  -0.636  -0.768  -0.809  -0.654
245   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
246   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
247   L         0.296   0.307   0.278  -0.054  -0.008  -0.074   0.093   0.106   0.005
248   N         1.284   1.305   1.383   1.430   1.459   1.573   1.384   1.414   1.531
249   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
250   R         1.284   1.305   1.383   1.412   1.449   1.556   1.384   1.414   1.531
251   P         1.284   1.305   1.383   1.432   1.446   1.574   1.384   1.414   1.531
252   S         0.122   0.210   0.260  -0.073   0.114   0.135  -0.230  -0.072  -0.030
253   K         1.284   1.305   1.383   1.315   1.355   1.464   1.384   1.414   1.531
254   L         0.622   0.590   0.395   0.385   0.386   0.088   0.631   0.579   0.223
255   P         0.622   0.590   0.395   0.854   0.802   0.514   0.631   0.579   0.223
256   D         1.284   1.305   1.383   1.201   1.213   1.356   1.384   1.414   1.531
257   V         0.622   0.546   0.393   0.713   0.610   0.371   0.631   0.511   0.219
258   C         1.284   1.305   1.383   1.460   1.482   1.602   1.384   1.414   1.531
259   Y         1.284   1.305   1.383   1.422   1.485   1.565   1.384   1.414   1.531
260   S         0.622   0.546   0.393   0.667   0.569   0.315   0.631   0.511   0.219
261   W         1.284   1.305   1.383   1.468   1.517   1.609   1.384   1.414   1.531
262   W         1.284   1.305   1.383   1.468   1.517   1.609   1.384   1.414   1.531
263   V         0.622   0.546   0.393   0.704   0.594   0.351   0.631   0.511   0.219
264   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
265   S         1.284   1.305   1.383   1.261   1.300   1.413   1.384   1.414   1.531
266   S        -0.601  -0.640  -0.826  -0.373  -0.422  -0.667  -0.553  -0.599  -0.803
267   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
268   A        -0.427  -0.439  -0.405  -0.566  -0.586  -0.513  -0.661  -0.662  -0.590
269   I         0.296   0.274   0.273   0.321   0.286   0.275   0.093   0.045  -0.004
270   I        -0.427  -0.420  -0.401  -0.692  -0.650  -0.600  -0.661  -0.641  -0.585
271   G        -0.297  -0.263  -0.374  -0.364  -0.359  -0.466  -0.445  -0.411  -0.545
272   R         0.296   0.358   0.283   0.302   0.404   0.256   0.093   0.195   0.015
273   L        -0.846  -0.833  -0.880  -1.090  -1.038  -1.083  -0.876  -0.857  -0.868
274   D        -0.427  -0.437  -0.407  -0.487  -0.492  -0.404  -0.661  -0.668  -0.594
275   W         1.284   1.305   1.383   1.468   1.517   1.609   1.384   1.414   1.531
276   I         0.622   0.609   0.398   0.724   0.707   0.398   0.631   0.609   0.229
277   N         0.296   0.363   0.282   0.199   0.278   0.168   0.093   0.204   0.014
278   Y        -1.759  -1.730  -1.618  -1.568  -1.516  -1.415  -1.414  -1.374  -1.207
279   E        -1.644  -1.630  -1.585  -1.447  -1.459  -1.355  -1.306  -1.288  -1.181
280   K        -0.008  -0.106  -0.305   0.184   0.064  -0.246  -0.015  -0.150  -0.439
281   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
282   T        -1.036  -1.063  -0.928  -0.978  -0.999  -0.826  -1.091  -1.103  -0.920
283   E        -1.340  -1.371  -1.298  -1.238  -1.291  -1.162  -1.199  -1.218  -1.084
284   F         0.622   0.661   0.401   0.804   0.849   0.500   0.631   0.687   0.233
285   I         0.622   0.546   0.393   0.677   0.572   0.277   0.631   0.511   0.219
286   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
287   K        -2.063  -2.055  -1.884  -1.858  -1.880  -1.624  -1.522  -1.501  -1.291
288   C        -0.846  -0.909  -0.888  -0.660  -0.763  -0.762  -0.876  -0.936  -0.878
289   Q         1.284   1.305   1.383   1.410   1.441   1.554   1.384   1.414   1.531
290   D         1.284   1.305   1.383   1.201   1.213   1.356   1.384   1.414   1.531
291   E        -1.759  -1.746  -1.616  -1.750  -1.726  -1.493  -1.414  -1.389  -1.206
292   K        -1.036  -0.941  -0.919  -1.160  -1.031  -0.977  -1.091  -0.982  -0.910
293   K        -0.846  -0.905  -0.881  -0.758  -0.844  -0.833  -0.876  -0.929  -0.870
294   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
295   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
296   I         0.296   0.247   0.250   0.276   0.181   0.165   0.093  -0.005  -0.048
297   S         0.296   0.251   0.260   0.209   0.123   0.107   0.093   0.002  -0.028
298   D         1.284   1.305   1.383   1.201   1.213   1.356   1.384   1.414   1.531
299   R         1.284   1.305   1.383   1.412   1.449   1.556   1.384   1.414   1.531
300   P        -0.297  -0.358  -0.386  -0.158  -0.252  -0.332  -0.445  -0.519  -0.560
301   E        -0.616  -0.590  -0.465  -0.938  -0.925  -0.700  -0.876  -0.836  -0.663
302   N         0.122   0.105   0.217   0.002  -0.075   0.095  -0.230  -0.272  -0.113
303   E        -1.340  -1.410  -1.303  -1.143  -1.227  -1.077  -1.199  -1.248  -1.088
304   V        -0.427  -0.436  -0.407  -0.492  -0.510  -0.445  -0.661  -0.669  -0.594
305   D         1.284   1.305   1.383   1.201   1.213   1.356   1.384   1.414   1.531
306   V         1.284   1.305   1.383   1.297   1.321   1.447   1.384   1.414   1.531
307   F        -0.427  -0.452  -0.399  -0.372  -0.384  -0.298  -0.661  -0.684  -0.585
308   H         1.284   1.305   1.383   1.458   1.513   1.600   1.384   1.414   1.531
309   T         1.284   1.305   1.383   1.375   1.416   1.521   1.384   1.414   1.531
310   V        -0.846  -0.739  -0.854  -0.699  -0.516  -0.758  -0.876  -0.732  -0.837
311   F         1.284   1.305   1.383   1.366   1.387   1.512   1.384   1.414   1.531
312   G        -0.008  -0.106  -0.305   0.032  -0.136  -0.412  -0.015  -0.150  -0.439
313   V        -0.427  -0.335  -0.397  -0.812  -0.678  -0.714  -0.661  -0.565  -0.582
314   A        -0.601  -0.546  -0.807  -0.397  -0.347  -0.702  -0.553  -0.482  -0.781
315   G         1.284   1.305   1.383   1.191   1.192   1.346   1.384   1.414   1.531
316   L         1.284   1.305   1.383   0.963   1.031   1.129   1.384   1.414   1.531
317   S         1.284   1.305   1.383   1.261   1.300   1.413   1.384   1.414   1.531
318   L         0.622   0.693   0.405   0.383   0.510   0.099   0.631   0.734   0.241
319   M        -0.616  -0.583  -0.461  -0.878  -0.851  -0.670  -0.876  -0.826  -0.658
320   G        -1.340  -1.346  -1.284  -1.371  -1.415  -1.265  -1.199  -1.198  -1.073
321   Y        -0.846  -0.848  -0.877  -0.654  -0.640  -0.726  -0.876  -0.875  -0.868
322   D        -0.616  -0.593  -0.458  -0.769  -0.743  -0.526  -0.876  -0.840  -0.654
323   N        -1.340  -1.296  -1.274  -1.265  -1.230  -1.155  -1.199  -1.148  -1.064
324   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   L        -0.297  -0.362  -0.387  -0.584  -0.642  -0.675  -0.445  -0.525  -0.559
327   V        -2.063  -1.966  -1.879  -1.855  -1.704  -1.613  -1.522  -1.437  -1.288
328   P        -1.340  -1.290  -1.271  -1.142  -1.073  -1.066  -1.199  -1.141  -1.061
329   I         0.122   0.105   0.217  -0.061  -0.115   0.061  -0.230  -0.272  -0.113
330   D         0.296   0.332   0.276   0.199   0.232   0.157   0.093   0.150   0.001
331   P         0.622   0.590   0.395   0.854   0.802   0.514   0.631   0.579   0.223
332   I        -0.297  -0.294  -0.366  -0.269  -0.248  -0.371  -0.445  -0.420  -0.530
333   Y         0.622   0.546   0.393   0.852   0.787   0.519   0.631   0.511   0.219
334   C         1.284   1.305   1.383   1.460   1.482   1.602   1.384   1.414   1.531
335   M         0.122   0.118   0.217  -0.048  -0.067   0.011  -0.230  -0.248  -0.112
336   P         1.284   1.305   1.383   1.432   1.446   1.574   1.384   1.414   1.531
337   K        -1.759  -1.755  -1.611  -1.597  -1.604  -1.411  -1.414  -1.395  -1.203
338   S        -1.036  -1.039  -0.927  -1.051  -1.038  -0.902  -1.091  -1.085  -0.919
339   V         0.622   0.590   0.395   0.729   0.687   0.414   0.631   0.579   0.223
340   T        -1.150  -1.134  -1.238  -0.833  -0.802  -0.993  -0.983  -0.959  -1.027
341   S        -1.759  -1.749  -1.612  -1.520  -1.479  -1.293  -1.414  -1.392  -1.203
342   K        -0.297  -0.271  -0.372  -0.209  -0.175  -0.311  -0.445  -0.425  -0.539
343   F        -1.340  -1.342  -1.288  -1.241  -1.247  -1.195  -1.199  -1.195  -1.075
344   K        -0.114  -0.079  -0.327   0.031   0.082  -0.294  -0.162  -0.113  -0.470
345   K        -1.051  -1.054  -0.930  -0.960  -0.955  -0.778  -1.103  -1.096  -0.921
346   Y        -1.542  -1.507  -1.335  -1.387  -1.346  -1.101  -1.371  -1.327  -1.114
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   P        -0.569  -0.507  -0.449  -0.825  -0.714  -0.620  -0.820  -0.743  -0.644
354   Y        -0.959  -0.943  -0.896  -0.947  -0.921  -0.859  -1.005  -0.969  -0.884
355   K        -1.759  -1.754  -1.611  -1.674  -1.688  -1.500  -1.414  -1.395  -1.202
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P20133
Output conservation file - output/P20133
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
