1     M         1.219   1.220   1.233   1.489   1.489   1.506   1.270   1.270   1.285
2     E        -0.325  -0.310  -0.384  -0.229  -0.207  -0.337  -0.417  -0.394  -0.502
3     S        -0.325  -0.310  -0.384  -0.492  -0.459  -0.562  -0.417  -0.394  -0.502
4     T        -1.446  -1.446  -1.410  -1.121  -1.127  -1.064  -1.260  -1.259  -1.202
5     S        -1.446  -1.446  -1.410  -1.565  -1.564  -1.501  -1.260  -1.259  -1.202
6     G        -1.446  -1.446  -1.410  -1.179  -1.183  -1.121  -1.260  -1.259  -1.202
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    E        -0.325  -0.338  -0.380  -0.115  -0.138  -0.209  -0.417  -0.436  -0.497
11    R        -0.462  -0.462  -0.434  -0.525  -0.530  -0.477  -0.628  -0.627  -0.580
12    S        -0.462  -0.462  -0.434  -0.663  -0.656  -0.613  -0.628  -0.627  -0.580
13    E        -0.462  -0.462  -0.434  -0.663  -0.656  -0.613  -0.628  -0.627  -0.580
14    N         1.219   1.220   1.233   1.130   1.137   1.153   1.270   1.270   1.285
15    I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
16    H        -0.462  -0.462  -0.434  -0.473  -0.476  -0.426  -0.628  -0.627  -0.580
17    E        -0.462  -0.462  -0.434  -0.473  -0.476  -0.426  -0.628  -0.627  -0.580
18    D        -0.325  -0.325  -0.385  -0.167  -0.172  -0.256  -0.417  -0.417  -0.505
19    Q        -0.325  -0.310  -0.384  -0.115  -0.093  -0.215  -0.417  -0.394  -0.502
20    G        -1.446  -1.446  -1.410  -1.261  -1.260  -1.201  -1.260  -1.259  -1.202
21    I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
22    P         1.219   1.220   1.233   1.325   1.325   1.345   1.270   1.270   1.285
23    K        -0.462  -0.462  -0.434  -0.604  -0.607  -0.555  -0.628  -0.627  -0.580
24    V        -0.462  -0.462  -0.434  -0.590  -0.586  -0.541  -0.628  -0.627  -0.580
25    I        -0.462  -0.462  -0.434  -0.696  -0.693  -0.645  -0.628  -0.627  -0.580
26    L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
27    P         1.219   1.220   1.233   1.325   1.325   1.345   1.270   1.270   1.285
28    A        -1.446  -1.446  -1.410  -1.161  -1.163  -1.103  -1.260  -1.259  -1.202
29    D        -0.325  -0.325  -0.385  -0.198  -0.202  -0.294  -0.417  -0.417  -0.505
30    F        -0.325  -0.325  -0.385  -0.115  -0.118  -0.219  -0.417  -0.417  -0.505
31    N        -0.325  -0.338  -0.380  -0.537  -0.565  -0.633  -0.417  -0.436  -0.497
32    K        -0.325  -0.325  -0.385  -0.315  -0.319  -0.405  -0.417  -0.417  -0.505
33    C         1.219   1.220   1.233   1.501   1.501   1.518   1.270   1.270   1.285
34    S        -0.325  -0.310  -0.384  -0.492  -0.459  -0.562  -0.417  -0.394  -0.502
35    R        -0.325  -0.310  -0.384  -0.263  -0.242  -0.370  -0.417  -0.394  -0.502
36    T        -0.325  -0.310  -0.384  -0.257  -0.240  -0.337  -0.417  -0.394  -0.502
37    D        -0.325  -0.325  -0.385  -0.134  -0.139  -0.216  -0.417  -0.417  -0.505
38    L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
39    V         1.219   1.220   1.233   1.294   1.293   1.315   1.270   1.270   1.285
40    V        -0.325  -0.310  -0.384  -0.300  -0.275  -0.414  -0.417  -0.394  -0.502
41    L        -0.325  -0.325  -0.385  -0.519  -0.522  -0.619  -0.417  -0.417  -0.505
42    I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
43    S        -0.325  -0.310  -0.384  -0.462  -0.430  -0.526  -0.417  -0.394  -0.502
44    R         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
45    M         1.219   1.220   1.233   1.489   1.489   1.506   1.270   1.270   1.285
46    L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
47    V        -1.446  -1.446  -1.410  -1.368  -1.364  -1.307  -1.260  -1.259  -1.202
48    S        -0.325  -0.338  -0.380  -0.263  -0.284  -0.390  -0.417  -0.436  -0.497
49    L        -0.325  -0.310  -0.384  -0.519  -0.497  -0.617  -0.417  -0.394  -0.502
50    I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
51    A        -0.325  -0.338  -0.380  -0.090  -0.113  -0.179  -0.417  -0.436  -0.497
52    I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
53    N         1.219   1.220   1.233   1.079   1.079   1.103   1.270   1.270   1.285
54    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    N        -0.325  -0.338  -0.380  -0.312  -0.340  -0.423  -0.417  -0.436  -0.497
56    S        -0.325  -0.325  -0.385  -0.462  -0.450  -0.527  -0.417  -0.417  -0.505
57    A        -0.325  -0.338  -0.380  -0.373  -0.394  -0.440  -0.417  -0.436  -0.497
58    T        -0.462  -0.462  -0.434  -0.632  -0.628  -0.582  -0.628  -0.627  -0.580
59    K        -0.325  -0.325  -0.385  -0.417  -0.421  -0.530  -0.417  -0.417  -0.505
60    K        -1.446  -1.446  -1.410  -1.227  -1.233  -1.168  -1.260  -1.259  -1.202
61    S        -1.446  -1.446  -1.410  -1.499  -1.494  -1.436  -1.260  -1.259  -1.202
62    D        -1.446  -1.446  -1.410  -1.344  -1.349  -1.284  -1.260  -1.259  -1.202
63    D        -1.446  -1.446  -1.410  -1.175  -1.180  -1.117  -1.260  -1.259  -1.202
64    Q        -1.446  -1.446  -1.410  -1.302  -1.304  -1.242  -1.260  -1.259  -1.202
65    I        -1.446  -1.446  -1.410  -1.212  -1.215  -1.153  -1.260  -1.259  -1.202
66    T        -1.446  -1.446  -1.410  -1.212  -1.219  -1.153  -1.260  -1.259  -1.202
67    L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
68    T         1.219   1.220   1.233   1.200   1.199   1.222   1.270   1.270   1.285
69    R         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
70    Y        -0.325  -0.338  -0.380  -0.115  -0.139  -0.211  -0.417  -0.436  -0.497
71    H         1.219   1.220   1.233   1.471   1.471   1.489   1.270   1.270   1.285
72    S         1.219   1.220   1.233   0.982   0.997   1.007   1.270   1.270   1.285
73    K         1.219   1.220   1.233   1.188   1.187   1.210   1.270   1.270   1.285
74    I        -0.325  -0.325  -0.385  -0.338  -0.336  -0.414  -0.417  -0.417  -0.505
75    P        -0.325  -0.338  -0.380  -0.123  -0.147  -0.217  -0.417  -0.436  -0.497
76    P         1.219   1.220   1.233   1.325   1.325   1.345   1.270   1.270   1.285
77    N        -0.325  -0.325  -0.385  -0.565  -0.561  -0.681  -0.417  -0.417  -0.505
78    I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
79    S        -0.325  -0.325  -0.385  -0.552  -0.542  -0.638  -0.417  -0.417  -0.505
80    I        -0.325  -0.338  -0.380  -0.300  -0.325  -0.408  -0.417  -0.436  -0.497
81    F        -0.325  -0.325  -0.385  -0.115  -0.118  -0.219  -0.417  -0.417  -0.505
82    N        -0.325  -0.325  -0.385  -0.370  -0.373  -0.442  -0.417  -0.417  -0.505
83    Y         1.219   1.220   1.233   1.319   1.319   1.339   1.270   1.270   1.285
84    F        -0.325  -0.325  -0.385  -0.229  -0.233  -0.359  -0.417  -0.417  -0.505
85    I        -0.325  -0.310  -0.384  -0.426  -0.400  -0.519  -0.417  -0.394  -0.502
86    R         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
87    L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
88    T         1.219   1.220   1.233   1.200   1.199   1.222   1.270   1.270   1.285
89    K         1.219   1.220   1.233   1.188   1.187   1.210   1.270   1.270   1.285
90    F        -0.325  -0.338  -0.380  -0.151  -0.173  -0.234  -0.417  -0.436  -0.497
91    S         1.219   1.220   1.233   0.982   0.997   1.007   1.270   1.270   1.285
92    S        -0.325  -0.310  -0.384  -0.620  -0.584  -0.719  -0.417  -0.394  -0.502
93    L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
94    E         1.219   1.220   1.233   1.331   1.331   1.351   1.270   1.270   1.285
95    H         1.219   1.220   1.233   1.471   1.471   1.489   1.270   1.270   1.285
96    C        -0.325  -0.338  -0.380  -0.405  -0.410  -0.454  -0.417  -0.436  -0.497
97    V         1.219   1.220   1.233   1.294   1.293   1.315   1.270   1.270   1.285
98    L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
99    M        -0.325  -0.338  -0.380  -0.341  -0.362  -0.397  -0.417  -0.436  -0.497
100   T        -0.325  -0.338  -0.380  -0.552  -0.561  -0.631  -0.417  -0.436  -0.497
101   S        -0.325  -0.338  -0.380  -0.274  -0.296  -0.401  -0.417  -0.436  -0.497
102   L        -0.325  -0.338  -0.380  -0.326  -0.355  -0.439  -0.417  -0.436  -0.497
103   Y         1.219   1.220   1.233   1.319   1.319   1.339   1.270   1.270   1.285
104   Y         1.219   1.220   1.233   1.319   1.319   1.339   1.270   1.270   1.285
105   I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
106   D         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
107   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
108   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
109   Q        -0.325  -0.338  -0.380  -0.459  -0.464  -0.518  -0.417  -0.436  -0.497
110   T        -1.446  -1.446  -1.410  -1.372  -1.374  -1.311  -1.260  -1.259  -1.202
111   V         1.219   1.220   1.233   1.294   1.293   1.315   1.270   1.270   1.285
112   Y         1.219   1.220   1.233   1.319   1.319   1.339   1.270   1.270   1.285
113   P         1.219   1.220   1.233   1.325   1.325   1.345   1.270   1.270   1.285
114   D        -1.446  -1.446  -1.410  -1.161  -1.166  -1.103  -1.260  -1.259  -1.202
115   F         1.219   1.220   1.233   1.398   1.399   1.417   1.270   1.270   1.285
116   T        -0.325  -0.310  -0.384  -0.405  -0.383  -0.517  -0.417  -0.394  -0.502
117   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
118   N         1.219   1.220   1.233   1.079   1.079   1.103   1.270   1.270   1.285
119   S         1.219   1.220   1.233   0.982   0.997   1.007   1.270   1.270   1.285
120   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
121   T         1.219   1.220   1.233   1.200   1.199   1.222   1.270   1.270   1.285
122   A        -0.325  -0.325  -0.385  -0.137  -0.141  -0.242  -0.417  -0.417  -0.505
123   H         1.219   1.220   1.233   1.471   1.471   1.489   1.270   1.270   1.285
124   R         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
125   F         1.219   1.220   1.233   1.398   1.399   1.417   1.270   1.270   1.285
126   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
127   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
128   T         1.219   1.220   1.233   1.200   1.199   1.222   1.270   1.270   1.285
129   A         1.219   1.220   1.233   1.386   1.386   1.405   1.270   1.270   1.285
130   T         1.219   1.220   1.233   1.200   1.199   1.222   1.270   1.270   1.285
131   T         1.219   1.220   1.233   1.200   1.199   1.222   1.270   1.270   1.285
132   V        -0.325  -0.338  -0.380  -0.382  -0.400  -0.460  -0.417  -0.436  -0.497
133   A         1.219   1.220   1.233   1.386   1.386   1.405   1.270   1.270   1.285
134   T        -0.325  -0.338  -0.380  -0.552  -0.561  -0.631  -0.417  -0.436  -0.497
135   K         1.219   1.220   1.233   1.188   1.187   1.210   1.270   1.270   1.285
136   G         1.219   1.220   1.233   1.398   1.398   1.417   1.270   1.270   1.285
137   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
138   C         1.219   1.220   1.233   1.501   1.501   1.518   1.270   1.270   1.285
139   D         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
140   S         1.219   1.220   1.233   0.982   0.997   1.007   1.270   1.270   1.285
141   F         1.219   1.220   1.233   1.398   1.399   1.417   1.270   1.270   1.285
142   S        -0.325  -0.338  -0.380  -0.167  -0.189  -0.301  -0.417  -0.436  -0.497
143   T         1.219   1.220   1.233   1.200   1.199   1.222   1.270   1.270   1.285
144   N         1.219   1.220   1.233   1.079   1.079   1.103   1.270   1.270   1.285
145   A        -0.325  -0.338  -0.380  -0.263  -0.286  -0.339  -0.417  -0.436  -0.497
146   H         1.219   1.220   1.233   1.471   1.471   1.489   1.270   1.270   1.285
147   Y         1.219   1.220   1.233   1.319   1.319   1.339   1.270   1.270   1.285
148   A        -0.325  -0.338  -0.380  -0.462  -0.468  -0.522  -0.417  -0.436  -0.497
149   K         1.219   1.220   1.233   1.188   1.187   1.210   1.270   1.270   1.285
150   V         1.219   1.220   1.233   1.294   1.293   1.315   1.270   1.270   1.285
151   G         1.219   1.220   1.233   1.398   1.398   1.417   1.270   1.270   1.285
152   G         1.219   1.220   1.233   1.398   1.398   1.417   1.270   1.270   1.285
153   V         1.219   1.220   1.233   1.294   1.293   1.315   1.270   1.270   1.285
154   R        -0.325  -0.338  -0.380  -0.129  -0.153  -0.226  -0.417  -0.436  -0.497
155   C         1.219   1.220   1.233   1.501   1.501   1.518   1.270   1.270   1.285
156   H        -1.446  -1.446  -1.410  -1.451  -1.439  -1.389  -1.260  -1.259  -1.202
157   E         1.219   1.220   1.233   1.331   1.331   1.351   1.270   1.270   1.285
158   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
159   N         1.219   1.220   1.233   1.079   1.079   1.103   1.270   1.270   1.285
160   I        -0.325  -0.310  -0.384  -0.382  -0.357  -0.465  -0.417  -0.394  -0.502
161   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
162   E         1.219   1.220   1.233   1.331   1.331   1.351   1.270   1.270   1.285
163   N         1.219   1.220   1.233   1.079   1.079   1.103   1.270   1.270   1.285
164   D        -0.325  -0.338  -0.380  -0.184  -0.208  -0.277  -0.417  -0.436  -0.497
165   F         1.219   1.220   1.233   1.398   1.399   1.417   1.270   1.270   1.285
166   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
167   K        -1.446  -1.446  -1.410  -1.279  -1.286  -1.220  -1.260  -1.259  -1.202
168   R        -0.325  -0.310  -0.384  -0.263  -0.242  -0.370  -0.417  -0.394  -0.502
169   V         1.219   1.220   1.233   1.294   1.293   1.315   1.270   1.270   1.285
170   N        -0.325  -0.325  -0.385  -0.414  -0.418  -0.496  -0.417  -0.417  -0.505
171   Y         1.219   1.220   1.233   1.319   1.319   1.339   1.270   1.270   1.285
172   R         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
173   I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
174   I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
175   P         1.219   1.220   1.233   1.325   1.325   1.345   1.270   1.270   1.285
176   R         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
177   D         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
178   H        -1.446  -1.446  -1.410  -1.257  -1.255  -1.198  -1.260  -1.259  -1.202
179   N         1.219   1.220   1.233   1.079   1.079   1.103   1.270   1.270   1.285
180   I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
181   T        -0.325  -0.325  -0.385  -0.289  -0.293  -0.377  -0.417  -0.417  -0.505
182   L        -1.446  -1.446  -1.410  -1.451  -1.461  -1.389  -1.260  -1.259  -1.202
183   C         1.219   1.220   1.233   1.501   1.501   1.518   1.270   1.270   1.285
184   S        -0.325  -0.338  -0.380  -0.462  -0.482  -0.575  -0.417  -0.436  -0.497
185   I        -0.325  -0.310  -0.384  -0.289  -0.266  -0.353  -0.417  -0.394  -0.502
186   E         1.219   1.220   1.233   1.331   1.331   1.351   1.270   1.270   1.285
187   Q        -0.325  -0.310  -0.384  -0.131  -0.110  -0.235  -0.417  -0.394  -0.502
188   K        -0.325  -0.310  -0.384  -0.272  -0.253  -0.351  -0.417  -0.394  -0.502
189   Q        -0.462  -0.462  -0.434  -0.487  -0.490  -0.439  -0.628  -0.627  -0.580
190   K        -0.462  -0.462  -0.434  -0.703  -0.707  -0.652  -0.628  -0.627  -0.580
191   K        -0.462  -0.462  -0.434  -0.487  -0.490  -0.439  -0.628  -0.627  -0.580
192   F         1.219   1.220   1.233   1.389   1.390   1.408   1.270   1.270   1.285
193   V        -0.462  -0.462  -0.434  -0.590  -0.586  -0.541  -0.628  -0.627  -0.580
194   I        -0.462  -0.462  -0.434  -0.754  -0.751  -0.702  -0.628  -0.627  -0.580
195   D        -0.462  -0.462  -0.434  -0.426  -0.429  -0.380  -0.628  -0.627  -0.580
196   K        -0.462  -0.462  -0.434  -0.535  -0.538  -0.486  -0.628  -0.627  -0.580
197   N        -0.462  -0.462  -0.434  -0.820  -0.817  -0.767  -0.628  -0.627  -0.580
198   A        -1.446  -1.446  -1.410  -1.435  -1.432  -1.373  -1.260  -1.259  -1.202
199   L        -1.446  -1.446  -1.410  -1.295  -1.304  -1.235  -1.260  -1.259  -1.202
200   G        -0.325  -0.338  -0.380  -0.456  -0.462  -0.514  -0.417  -0.436  -0.497
201   S        -1.446  -1.446  -1.410  -1.565  -1.564  -1.501  -1.260  -1.259  -1.202
202   L        -0.325  -0.325  -0.385  -0.341  -0.346  -0.402  -0.417  -0.417  -0.505
203   D        -1.446  -1.446  -1.410  -1.321  -1.329  -1.261  -1.260  -1.259  -1.202
204   L        -1.446  -1.446  -1.410  -1.475  -1.481  -1.412  -1.260  -1.259  -1.202
205   D        -1.446  -1.446  -1.410  -1.407  -1.397  -1.345  -1.260  -1.259  -1.202
206   -        -0.462  -0.462  -0.434  -0.482  -0.482  -0.434  -0.628  -0.627  -0.580
207   S        -1.446  -1.446  -1.410  -1.495  -1.495  -1.432  -1.260  -1.259  -1.202
208   Y        -1.446  -1.446  -1.410  -1.295  -1.299  -1.235  -1.260  -1.259  -1.202
209   S        -1.446  -1.446  -1.410  -1.306  -1.306  -1.246  -1.260  -1.259  -1.202
210   Y        -0.325  -0.325  -0.385  -0.338  -0.334  -0.470  -0.417  -0.417  -0.505
211   V        -1.446  -1.446  -1.410  -1.368  -1.358  -1.307  -1.260  -1.259  -1.202
212   N        -1.446  -1.446  -1.410  -1.565  -1.558  -1.501  -1.260  -1.259  -1.202
213   R        -1.446  -1.446  -1.410  -1.279  -1.278  -1.220  -1.260  -1.259  -1.202
214   P        -0.325  -0.310  -0.384  -0.332  -0.300  -0.462  -0.417  -0.394  -0.502
215   K        -1.446  -1.446  -1.410  -1.435  -1.438  -1.373  -1.260  -1.259  -1.202
216   S        -1.446  -1.446  -1.410  -1.507  -1.507  -1.444  -1.260  -1.259  -1.202
217   G         1.219   1.220   1.233   1.398   1.398   1.417   1.270   1.270   1.285
218   Y        -0.325  -0.325  -0.385  -0.151  -0.154  -0.241  -0.417  -0.417  -0.505
219   N         1.219   1.220   1.233   1.079   1.079   1.103   1.270   1.270   1.285
220   V         1.219   1.220   1.233   1.294   1.293   1.315   1.270   1.270   1.285
221   L         1.219   1.220   1.233   1.060   1.057   1.084   1.270   1.270   1.285
222   D        -1.446  -1.446  -1.410  -1.234  -1.237  -1.175  -1.260  -1.259  -1.202
223   K        -1.446  -1.446  -1.410  -1.435  -1.441  -1.373  -1.260  -1.259  -1.202
224   Y         1.219   1.220   1.233   1.319   1.319   1.339   1.270   1.270   1.285
225   Y         1.219   1.220   1.233   1.319   1.319   1.339   1.270   1.270   1.285
226   R        -0.325  -0.310  -0.384  -0.204  -0.184  -0.298  -0.417  -0.394  -0.502
227   R        -0.325  -0.338  -0.380  -0.315  -0.339  -0.398  -0.417  -0.436  -0.497
228   I         1.219   1.220   1.233   1.118   1.123   1.141   1.270   1.270   1.285
229   V        -0.325  -0.310  -0.384  -0.300  -0.275  -0.414  -0.417  -0.394  -0.502
230   Q        -0.325  -0.310  -0.384  -0.115  -0.093  -0.215  -0.417  -0.394  -0.502
231   L        -0.325  -0.310  -0.384  -0.435  -0.418  -0.514  -0.417  -0.394  -0.502
232   V         1.219   1.220   1.233   1.294   1.293   1.315   1.270   1.270   1.285
233   G         1.219   1.220   1.233   1.398   1.398   1.417   1.270   1.270   1.285
234   S        -1.446  -1.446  -1.410  -1.641  -1.638  -1.576  -1.260  -1.259  -1.202
235   F        -1.446  -1.446  -1.410  -1.146  -1.148  -1.089  -1.260  -1.259  -1.202
236   N        -1.446  -1.446  -1.410  -1.728  -1.722  -1.662  -1.260  -1.259  -1.202
237   A        -1.446  -1.446  -1.410  -1.507  -1.495  -1.444  -1.260  -1.259  -1.202
238   S         1.219   1.220   1.233   0.982   0.997   1.007   1.270   1.270   1.285
239   P         1.219   1.220   1.233   1.325   1.325   1.345   1.270   1.270   1.285
240   D         1.219   1.220   1.233   1.300   1.299   1.321   1.270   1.270   1.285
241   K         1.219   1.220   1.233   1.188   1.187   1.210   1.270   1.270   1.285
242   S        -0.325  -0.338  -0.380  -0.450  -0.471  -0.564  -0.417  -0.436  -0.497
243   R        -1.446  -1.446  -1.410  -1.495  -1.489  -1.432  -1.260  -1.259  -1.202
244   K        -0.325  -0.325  -0.385  -0.361  -0.366  -0.462  -0.417  -0.417  -0.505
245   V        -0.325  -0.325  -0.385  -0.209  -0.214  -0.306  -0.417  -0.417  -0.505
246   D        -1.446  -1.446  -1.410  -1.302  -1.303  -1.242  -1.260  -1.259  -1.202
247   Y        -0.325  -0.325  -0.385  -0.151  -0.154  -0.241  -0.417  -0.417  -0.505
248   -        -0.462  -0.462  -0.434  -0.488  -0.488  -0.440  -0.628  -0.627  -0.580
249   -        -0.462  -0.462  -0.434  -0.457  -0.457  -0.410  -0.628  -0.627  -0.580
250   -        -0.462  -0.462  -0.434  -0.401  -0.401  -0.355  -0.628  -0.627  -0.580
251   -        -0.462  -0.462  -0.434  -0.292  -0.292  -0.248  -0.628  -0.627  -0.580
252   -         1.219   1.220   1.233   1.303   1.304   1.323   1.270   1.270   1.285
253   -        -0.462  -0.462  -0.434  -0.245  -0.245  -0.201  -0.628  -0.627  -0.580
254   -        -0.462  -0.462  -0.434  -0.721  -0.721  -0.669  -0.628  -0.627  -0.580
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -         1.219   1.220   1.233   1.181   1.183   1.204   1.270   1.270   1.285
261   -         1.219   1.220   1.233   1.066   1.067   1.090   1.270   1.270   1.285
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -0.462  -0.462  -0.434  -0.298  -0.298  -0.253  -0.628  -0.627  -0.580
265   -        -0.462  -0.462  -0.434  -0.377  -0.377  -0.331  -0.628  -0.627  -0.580
266   -        -0.462  -0.462  -0.434  -0.377  -0.377  -0.331  -0.628  -0.627  -0.580
267   -        -0.462  -0.462  -0.434  -0.843  -0.844  -0.790  -0.628  -0.627  -0.580
268   -        -0.462  -0.462  -0.434  -0.500  -0.501  -0.453  -0.628  -0.627  -0.580
269   -        -0.462  -0.462  -0.434  -0.450  -0.451  -0.403  -0.628  -0.627  -0.580
270   -        -0.462  -0.462  -0.434  -0.570  -0.571  -0.521  -0.628  -0.627  -0.580
271   -         1.219   1.220   1.233   1.199   1.200   1.221   1.270   1.270   1.285
272   -         1.219   1.220   1.233   1.021   1.022   1.046   1.270   1.270   1.285
273   -        -0.462  -0.462  -0.434  -0.488  -0.488  -0.440  -0.628  -0.627  -0.580
274   -        -0.462  -0.462  -0.434  -0.808  -0.809  -0.756  -0.628  -0.627  -0.580
275   -        -0.462  -0.462  -0.434  -0.721  -0.721  -0.669  -0.628  -0.627  -0.580
276   -        -0.462  -0.462  -0.434  -0.615  -0.616  -0.566  -0.628  -0.627  -0.580
277   -        -0.462  -0.462  -0.434  -0.721  -0.721  -0.669  -0.628  -0.627  -0.580
278   -        -0.462  -0.462  -0.434  -0.577  -0.577  -0.528  -0.628  -0.627  -0.580
279   -         1.219   1.220   1.233   1.021   1.022   1.046   1.270   1.270   1.285
280   -        -0.462  -0.462  -0.434  -0.364  -0.365  -0.319  -0.628  -0.627  -0.580
281   -        -0.462  -0.462  -0.434  -0.371  -0.371  -0.325  -0.628  -0.627  -0.580
282   -        -0.462  -0.462  -0.434  -0.701  -0.701  -0.650  -0.628  -0.627  -0.580
283   -        -0.462  -0.462  -0.434  -0.564  -0.564  -0.515  -0.628  -0.627  -0.580
284   -        -0.462  -0.462  -0.434  -0.721  -0.721  -0.669  -0.628  -0.627  -0.580
285   -         1.219   1.220   1.233   1.021   1.022   1.046   1.270   1.270   1.285
286   -        -0.462  -0.462  -0.434  -0.795  -0.796  -0.742  -0.628  -0.627  -0.580
287   -         1.219   1.220   1.233   1.102   1.103   1.125   1.270   1.270   1.285
288   -        -0.462  -0.462  -0.434  -0.628  -0.629  -0.579  -0.628  -0.627  -0.580
289   -        -0.462  -0.462  -0.434  -0.674  -0.675  -0.624  -0.628  -0.627  -0.580
290   -        -0.462  -0.462  -0.434  -0.526  -0.526  -0.478  -0.628  -0.627  -0.580
291   -        -0.462  -0.462  -0.434  -0.328  -0.328  -0.283  -0.628  -0.627  -0.580
292   V        -1.446  -1.446  -1.410  -1.295  -1.299  -1.235  -1.260  -1.259  -1.202
293   L        -0.325  -0.338  -0.380  -0.492  -0.514  -0.593  -0.417  -0.436  -0.497
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   P         1.219   1.220   1.233   1.325   1.325   1.345   1.270   1.270   1.285
297   P        -1.446  -1.446  -1.410  -1.348  -1.344  -1.288  -1.260  -1.259  -1.202
298   -        -0.462  -0.462  -0.434  -0.795  -0.796  -0.742  -0.628  -0.627  -0.580
299   -        -0.462  -0.462  -0.434  -0.519  -0.520  -0.471  -0.628  -0.627  -0.580
300   -        -0.462  -0.462  -0.434  -0.444  -0.445  -0.397  -0.628  -0.627  -0.580
301   -        -0.462  -0.462  -0.434  -0.463  -0.463  -0.416  -0.628  -0.627  -0.580
302   -        -0.462  -0.462  -0.434  -0.407  -0.408  -0.361  -0.628  -0.627  -0.580
303   N        -0.325  -0.325  -0.385  -0.565  -0.561  -0.681  -0.417  -0.417  -0.505
304   I        -0.325  -0.338  -0.380  -0.204  -0.228  -0.318  -0.417  -0.436  -0.497
305   D        -0.325  -0.325  -0.385  -0.312  -0.316  -0.433  -0.417  -0.417  -0.505
306   I        -1.446  -1.446  -1.410  -1.557  -1.560  -1.493  -1.260  -1.259  -1.202
307   V        -0.325  -0.325  -0.385  -0.361  -0.359  -0.492  -0.417  -0.417  -0.505
308   S        -0.325  -0.338  -0.380  -0.326  -0.347  -0.449  -0.417  -0.436  -0.497
309   E        -0.325  -0.325  -0.385  -0.107  -0.109  -0.190  -0.417  -0.417  -0.505
310   S        -0.325  -0.338  -0.380  -0.355  -0.377  -0.476  -0.417  -0.436  -0.497
311   G        -1.446  -1.446  -1.410  -1.135  -1.141  -1.078  -1.260  -1.259  -1.202
312   S        -1.446  -1.446  -1.410  -1.633  -1.628  -1.568  -1.260  -1.259  -1.202
313   Q        -1.446  -1.446  -1.410  -1.283  -1.280  -1.224  -1.260  -1.259  -1.202
314   T        -1.446  -1.446  -1.410  -1.475  -1.472  -1.412  -1.260  -1.259  -1.202
315   T        -1.446  -1.446  -1.410  -1.403  -1.403  -1.342  -1.260  -1.259  -1.202
316   Q        -0.325  -0.338  -0.380  -0.142  -0.164  -0.227  -0.417  -0.436  -0.497
317   L        -1.446  -1.446  -1.410  -1.419  -1.429  -1.357  -1.260  -1.259  -1.202
318   K        -0.325  -0.325  -0.385  -0.462  -0.459  -0.585  -0.417  -0.417  -0.505
319   G        -1.446  -1.446  -1.410  -1.364  -1.353  -1.303  -1.260  -1.259  -1.202
320   S        -1.446  -1.446  -1.410  -1.641  -1.638  -1.576  -1.260  -1.259  -1.202
321   S        -1.446  -1.446  -1.410  -1.283  -1.284  -1.224  -1.260  -1.259  -1.202
322   S        -0.325  -0.338  -0.380  -0.565  -0.584  -0.672  -0.417  -0.436  -0.497
323   P        -1.446  -1.446  -1.410  -1.471  -1.464  -1.408  -1.260  -1.259  -1.202
324   N        -0.325  -0.325  -0.385  -0.414  -0.418  -0.496  -0.417  -0.417  -0.505
325   -        -0.462  -0.462  -0.434  -0.577  -0.577  -0.528  -0.628  -0.627  -0.580
326   -        -0.462  -0.462  -0.434  -0.609  -0.610  -0.559  -0.628  -0.627  -0.580
327   -        -0.462  -0.462  -0.434  -0.364  -0.365  -0.319  -0.628  -0.627  -0.580
328   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
329   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
330   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
331   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   S        -0.325  -0.325  -0.385  -0.592  -0.578  -0.687  -0.417  -0.417  -0.505
333   H        -1.446  -1.446  -1.410  -1.376  -1.363  -1.315  -1.260  -1.259  -1.202
334   S        -0.325  -0.325  -0.385  -0.592  -0.578  -0.687  -0.417  -0.417  -0.505
335   S        -1.446  -1.446  -1.410  -1.395  -1.394  -1.334  -1.260  -1.259  -1.202
336   Q        -0.325  -0.310  -0.384  -0.178  -0.155  -0.292  -0.417  -0.394  -0.502
337   K         1.219   1.220   1.233   1.188   1.187   1.210   1.270   1.270   1.285
338   R        -0.325  -0.310  -0.384  -0.170  -0.151  -0.257  -0.417  -0.394  -0.502
339   Y        -1.446  -1.446  -1.410  -1.467  -1.464  -1.404  -1.260  -1.259  -1.202
340   S        -1.446  -1.446  -1.410  -1.364  -1.361  -1.303  -1.260  -1.259  -1.202
341   E        -0.325  -0.325  -0.385  -0.235  -0.238  -0.347  -0.417  -0.417  -0.505
342   A        -1.446  -1.446  -1.410  -1.161  -1.163  -1.103  -1.260  -1.259  -1.202
343   K        -0.325  -0.325  -0.385  -0.315  -0.319  -0.405  -0.417  -0.417  -0.505
344   D        -0.325  -0.310  -0.384  -0.263  -0.242  -0.370  -0.417  -0.394  -0.502
345   A        -1.446  -1.446  -1.410  -1.295  -1.293  -1.235  -1.260  -1.259  -1.202
346   H        -1.446  -1.446  -1.410  -1.132  -1.134  -1.074  -1.260  -1.259  -1.202
347   I        -0.325  -0.325  -0.385  -0.483  -0.481  -0.591  -0.417  -0.417  -0.505
348   Y        -1.446  -1.446  -1.410  -1.246  -1.246  -1.187  -1.260  -1.259  -1.202
349   N        -0.325  -0.338  -0.380  -0.312  -0.340  -0.423  -0.417  -0.436  -0.497
350   K        -1.446  -1.446  -1.410  -1.435  -1.438  -1.373  -1.260  -1.259  -1.202
351   R        -1.446  -1.446  -1.410  -1.495  -1.486  -1.432  -1.260  -1.259  -1.202
352   S        -0.325  -0.310  -0.384  -0.592  -0.553  -0.685  -0.417  -0.394  -0.502
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   K        -0.325  -0.310  -0.384  -0.306  -0.287  -0.392  -0.417  -0.394  -0.502
361   P        -0.325  -0.325  -0.385  -0.297  -0.302  -0.422  -0.417  -0.417  -0.505
362   D        -0.325  -0.338  -0.380  -0.504  -0.512  -0.572  -0.417  -0.436  -0.497
363   -         1.219   1.220   1.233   1.039   1.041   1.064   1.270   1.270   1.285
364   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
365   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   -        -0.462  -0.462  -0.434  -0.781  -0.782  -0.729  -0.628  -0.627  -0.580
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P20052
Output conservation file - output/P20052
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
