1     M         1.266   1.317   1.362   1.419   1.488   1.558   1.359   1.429   1.498
2     I        -1.353  -1.245  -1.244  -1.338  -1.179  -1.164  -1.217  -1.093  -1.044
3     R        -1.353  -1.356  -1.259  -1.326  -1.339  -1.169  -1.217  -1.189  -1.056
4     I        -2.022  -1.927  -1.840  -1.918  -1.711  -1.651  -1.489  -1.385  -1.262
5     C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     I        -0.985  -0.883  -0.879  -1.106  -0.951  -0.956  -1.033  -0.901  -0.875
9     V        -0.517  -0.497  -0.415  -0.693  -0.659  -0.529  -0.767  -0.721  -0.609
10    R         0.421   0.315   0.303   0.380   0.213   0.188   0.296   0.096   0.045
11    S        -1.454  -1.366  -1.286  -1.540  -1.403  -1.288  -1.299  -1.190  -1.078
12    K        -0.517  -0.382  -0.415  -0.827  -0.585  -0.640  -0.767  -0.577  -0.609
13    V        -0.985  -0.874  -0.878  -1.220  -1.062  -1.052  -1.033  -0.891  -0.874
14    P        -0.981  -0.995  -0.897  -1.041  -1.060  -0.908  -1.040  -1.027  -0.896
15    L        -0.491  -0.361  -0.408  -0.706  -0.493  -0.594  -0.717  -0.526  -0.598
16    L        -0.491  -0.361  -0.408  -0.638  -0.434  -0.517  -0.717  -0.526  -0.598
17    G         0.095   0.143   0.223  -0.079  -0.005   0.120  -0.302  -0.227  -0.108
18    T        -1.077  -1.019  -0.919  -1.282  -1.210  -1.039  -1.133  -1.047  -0.917
19    F        -0.491  -0.469  -0.419  -0.698  -0.668  -0.608  -0.717  -0.683  -0.613
20    L        -0.491  -0.361  -0.408  -0.673  -0.464  -0.558  -0.717  -0.526  -0.598
21    R        -0.200  -0.239  -0.371  -0.245  -0.319  -0.554  -0.302  -0.372  -0.545
22    S         1.266   1.317   1.362   1.236   1.304   1.382   1.359   1.429   1.498
23    D        -1.454  -1.369  -1.286  -1.444  -1.319  -1.196  -1.299  -1.193  -1.078
24    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    L        -0.443  -0.476  -0.403  -0.595  -0.626  -0.532  -0.671  -0.691  -0.595
27    A        -0.443  -0.346  -0.372  -0.727  -0.554  -0.598  -0.671  -0.510  -0.549
28    P        -1.371  -1.229  -1.252  -1.246  -1.050  -1.071  -1.225  -1.068  -1.049
29    H        -1.353  -1.284  -1.258  -1.218  -1.144  -1.057  -1.217  -1.133  -1.055
30    A        -0.892  -0.748  -0.869  -1.054  -0.879  -0.987  -0.946  -0.798  -0.868
31    L        -0.892  -0.874  -0.870  -0.950  -0.928  -0.917  -0.946  -0.911  -0.867
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    A        -1.688  -1.573  -1.554  -1.593  -1.428  -1.396  -1.353  -1.227  -1.162
35    L        -1.353  -1.312  -1.252  -1.381  -1.352  -1.232  -1.217  -1.153  -1.051
36    R        -1.688  -1.598  -1.562  -1.481  -1.384  -1.294  -1.353  -1.251  -1.168
37    R        -0.684  -0.737  -0.842  -0.542  -0.591  -0.735  -0.675  -0.734  -0.834
38    A        -1.227  -1.086  -1.208  -1.221  -1.024  -1.179  -1.082  -0.921  -1.008
39    I        -2.022  -1.927  -1.840  -1.789  -1.595  -1.527  -1.489  -1.385  -1.262
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    C        -1.688  -1.671  -1.579  -1.588  -1.575  -1.415  -1.353  -1.307  -1.181
42    K        -1.353  -1.313  -1.253  -1.352  -1.309  -1.200  -1.217  -1.153  -1.052
43    N        -0.684  -0.626  -0.807  -0.517  -0.447  -0.668  -0.675  -0.612  -0.795
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    V        -0.079   0.156  -0.261   0.005   0.305  -0.228  -0.133   0.197  -0.390
46    A        -1.353  -1.310  -1.253  -1.442  -1.378  -1.266  -1.217  -1.151  -1.051
47    L        -1.227  -1.273  -1.250  -1.041  -1.131  -1.064  -1.082  -1.112  -1.047
48    R        -1.018  -0.880  -0.896  -1.040  -0.837  -0.864  -1.082  -0.916  -0.895
49    S        -1.353  -1.336  -1.260  -1.244  -1.205  -1.096  -1.217  -1.169  -1.057
50    Y        -0.349  -0.203  -0.350  -0.260  -0.042  -0.260  -0.539  -0.336  -0.519
51    S        -1.227  -1.272  -1.244  -1.066  -1.170  -1.123  -1.082  -1.111  -1.042
52    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
54    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    -         0.421   0.362   0.335   0.412   0.310   0.234   0.296   0.181   0.105
63    -        -0.985  -0.836  -0.879  -1.088  -0.826  -0.945  -1.033  -0.839  -0.875
64    -        -0.517  -0.490  -0.415  -0.701  -0.649  -0.527  -0.767  -0.713  -0.609
65    -        -1.371  -1.339  -1.276  -1.365  -1.357  -1.250  -1.225  -1.170  -1.070
66    -        -1.371  -1.181  -1.251  -1.309  -1.051  -1.110  -1.225  -1.007  -1.048
67    -        -1.762  -1.688  -1.586  -1.672  -1.608  -1.415  -1.409  -1.316  -1.186
68    -        -1.371  -1.357  -1.266  -1.173  -1.186  -1.036  -1.225  -1.185  -1.061
69    F        -1.353  -1.192  -1.253  -1.291  -1.025  -1.118  -1.217  -1.034  -1.051
70    D        -0.892  -0.998  -0.897  -0.848  -0.990  -0.837  -0.946  -1.026  -0.896
71    I        -1.353  -1.318  -1.253  -1.376  -1.328  -1.221  -1.217  -1.157  -1.052
72    S        -0.892  -0.920  -0.883  -0.975  -1.029  -0.950  -0.946  -0.954  -0.882
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    K        -0.349  -0.371  -0.378  -0.358  -0.366  -0.394  -0.539  -0.546  -0.558
84    L        -1.227  -1.310  -1.266  -1.081  -1.182  -1.140  -1.082  -1.143  -1.061
85    T        -0.684  -0.684  -0.830  -0.543  -0.559  -0.767  -0.675  -0.663  -0.821
86    R        -0.079  -0.302  -0.354  -0.031  -0.352  -0.438  -0.133  -0.442  -0.522
87    N        -1.227  -1.143  -1.212  -1.041  -0.974  -1.039  -1.082  -0.986  -1.012
88    E        -0.684  -0.737  -0.842  -0.484  -0.600  -0.736  -0.675  -0.734  -0.834
89    I        -1.227  -1.310  -1.266  -1.098  -1.205  -1.155  -1.082  -1.143  -1.061
90    Q        -0.892  -0.844  -0.849  -0.871  -0.791  -0.807  -0.946  -0.856  -0.844
91    Q        -0.431  -0.374  -0.385  -0.497  -0.431  -0.420  -0.675  -0.593  -0.576
92    L        -0.349  -0.278  -0.374  -0.492  -0.432  -0.557  -0.539  -0.471  -0.558
93    R        -1.227  -1.310  -1.266  -1.244  -1.397  -1.345  -1.082  -1.143  -1.061
94    E        -1.688  -1.671  -1.579  -1.512  -1.494  -1.353  -1.353  -1.307  -1.181
95    L        -2.022  -1.927  -1.840  -1.786  -1.689  -1.524  -1.489  -1.385  -1.262
96    K        -0.349  -0.371  -0.378  -0.456  -0.475  -0.533  -0.539  -0.546  -0.558
97    R        -1.688  -1.589  -1.560  -1.450  -1.318  -1.248  -1.353  -1.245  -1.167
98    A        -1.353  -1.352  -1.273  -1.381  -1.354  -1.241  -1.217  -1.186  -1.068
99    R        -1.018  -0.882  -0.895  -1.149  -0.925  -0.964  -1.082  -0.919  -0.895
100   E        -1.688  -1.648  -1.569  -1.688  -1.654  -1.493  -1.353  -1.292  -1.174
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   R         1.266   1.317   1.362   1.197   1.268   1.345   1.359   1.429   1.498
106   K        -0.892  -0.983  -0.879  -0.852  -0.922  -0.793  -0.946  -1.009  -0.878
107   F        -0.431  -0.444  -0.386  -0.519  -0.521  -0.430  -0.675  -0.660  -0.575
108   K        -0.684  -0.845  -0.860  -0.574  -0.827  -0.884  -0.675  -0.858  -0.855
109   D        -0.892  -0.998  -0.897  -0.832  -0.979  -0.837  -0.946  -1.026  -0.896
110   R        -0.079  -0.302  -0.354  -0.001  -0.304  -0.376  -0.133  -0.442  -0.522
111   T        -0.079  -0.302  -0.354   0.020  -0.312  -0.406  -0.133  -0.442  -0.522
112   V        -0.431  -0.432  -0.394  -0.684  -0.680  -0.605  -0.675  -0.640  -0.583
113   A        -0.684  -0.845  -0.860  -0.729  -0.981  -1.002  -0.675  -0.858  -0.855
114   F        -0.892  -0.970  -0.879  -0.887  -0.989  -0.881  -0.946  -0.994  -0.876
115   Y         0.573   0.427   0.365   0.704   0.498   0.372   0.545   0.295   0.160
116   F        -0.892  -0.998  -0.897  -0.921  -1.055  -0.898  -0.946  -1.026  -0.896
117   S        -1.688  -1.614  -1.577  -1.673  -1.572  -1.483  -1.353  -1.268  -1.179
118   S         0.573   0.427   0.365   0.600   0.384   0.305   0.545   0.295   0.160
119   V        -0.684  -0.682  -0.816  -0.571  -0.591  -0.783  -0.675  -0.675  -0.805
120   A        -1.227  -1.310  -1.266  -1.228  -1.347  -1.257  -1.082  -1.143  -1.061
121   V        -0.349  -0.473  -0.401  -0.430  -0.622  -0.524  -0.539  -0.690  -0.594
122   L        -1.688  -1.666  -1.580  -1.705  -1.698  -1.570  -1.353  -1.303  -1.181
123   F         0.573   0.427   0.365   0.580   0.376   0.264   0.545   0.295   0.160
124   L         0.573   0.427   0.365   0.628   0.425   0.330   0.545   0.295   0.160
125   G        -0.349  -0.424  -0.387  -0.437  -0.556  -0.524  -0.539  -0.617  -0.571
126   L        -0.079  -0.170  -0.312  -0.027  -0.172  -0.418  -0.133  -0.268  -0.462
127   A        -0.684  -0.832  -0.855  -0.725  -0.972  -0.985  -0.675  -0.844  -0.848
128   Y        -0.349  -0.424  -0.387  -0.349  -0.446  -0.426  -0.539  -0.617  -0.571
129   A        -0.684  -0.845  -0.860  -0.712  -0.952  -0.970  -0.675  -0.858  -0.855
130   A         0.573   0.427   0.365   0.478   0.270   0.177   0.545   0.295   0.160
131   V         0.573   0.427   0.365   0.611   0.389   0.293   0.545   0.295   0.160
132   P         1.266   1.317   1.362   1.289   1.359   1.433   1.359   1.429   1.498
133   L        -0.684  -0.845  -0.860  -0.572  -0.814  -0.857  -0.675  -0.858  -0.855
134   Y         0.573   0.427   0.365   0.742   0.560   0.458   0.545   0.295   0.160
135   R         0.573   0.427   0.365   0.576   0.377   0.282   0.545   0.295   0.160
136   A        -0.079  -0.302  -0.354  -0.146  -0.473  -0.572  -0.133  -0.442  -0.522
137   I         0.573   0.502   0.374   0.601   0.527   0.305   0.545   0.423   0.178
138   C         1.266   1.317   1.362   1.461   1.528   1.599   1.359   1.429   1.498
139   A         0.112   0.240   0.267  -0.156   0.077   0.112  -0.268  -0.042  -0.025
140   R        -0.079  -0.302  -0.354  -0.030  -0.357  -0.436  -0.133  -0.442  -0.522
141   T         0.573   0.502   0.374   0.654   0.568   0.394   0.545   0.423   0.178
142   G         1.266   1.317   1.362   1.299   1.365   1.443   1.359   1.429   1.498
143   F        -0.557  -0.396  -0.406  -0.526  -0.224  -0.294  -0.811  -0.575  -0.595
144   G         1.266   1.317   1.362   1.299   1.365   1.443   1.359   1.429   1.498
145   G         1.266   1.317   1.362   1.299   1.365   1.443   1.359   1.429   1.498
146   I        -0.833  -0.849  -0.874  -0.802  -0.827  -0.874  -0.856  -0.873  -0.870
147   P         0.573   0.502   0.374   0.679   0.584   0.392   0.545   0.423   0.178
148   I         0.573   0.427   0.365   0.601   0.414   0.289   0.545   0.295   0.160
149   T         0.573   0.427   0.365   0.615   0.401   0.291   0.545   0.295   0.160
150   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
151   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
152   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
156   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
157   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
158   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   D         0.573   0.502   0.374   0.647   0.565   0.363   0.545   0.423   0.178
161   R        -0.892  -0.793  -0.859  -0.917  -0.744  -0.846  -0.946  -0.804  -0.855
162   R        -0.892  -0.998  -0.897  -0.956  -1.086  -0.939  -0.946  -1.026  -0.896
163   K        -0.349  -0.469  -0.399  -0.425  -0.614  -0.527  -0.539  -0.684  -0.590
164   F         0.573   0.427   0.365   0.589   0.395   0.283   0.545   0.295   0.160
165   T        -0.079  -0.302  -0.354  -0.014  -0.360  -0.478  -0.133  -0.442  -0.522
166   D        -0.557  -0.524  -0.439  -0.782  -0.764  -0.629  -0.811  -0.756  -0.641
167   D        -0.079  -0.302  -0.354   0.012  -0.326  -0.439  -0.133  -0.442  -0.522
168   K         0.573   0.502   0.374   0.633   0.548   0.324   0.545   0.423   0.178
169   L         1.266   1.317   1.362   1.238   1.310   1.384   1.359   1.429   1.498
170   I        -0.079  -0.302  -0.354   0.009  -0.285  -0.401  -0.133  -0.442  -0.522
171   P         1.266   1.317   1.362   1.289   1.359   1.433   1.359   1.429   1.498
172   V         0.573   0.502   0.374   0.613   0.513   0.314   0.545   0.423   0.178
173   D        -0.079  -0.302  -0.354   0.029  -0.296  -0.403  -0.133  -0.442  -0.522
174   T        -0.684  -0.781  -0.851  -0.561  -0.728  -0.830  -0.675  -0.793  -0.844
175   E        -0.892  -0.903  -0.873  -0.794  -0.854  -0.795  -0.946  -0.942  -0.873
176   K         0.573   0.502   0.374   0.633   0.548   0.324   0.545   0.423   0.178
177   R         0.573   0.502   0.374   0.607   0.530   0.366   0.545   0.423   0.178
178   I         0.573   0.427   0.365   0.631   0.467   0.359   0.545   0.295   0.160
179   R         1.266   1.317   1.362   1.187   1.257   1.335   1.359   1.429   1.498
180   I         0.255   0.244   0.245   0.122   0.104   0.068   0.003  -0.035  -0.067
181   S        -0.557  -0.524  -0.439  -0.735  -0.701  -0.552  -0.811  -0.756  -0.641
182   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
183   T         0.255   0.172   0.229   0.133  -0.054   0.038   0.003  -0.172  -0.097
184   S        -0.892  -0.998  -0.897  -0.854  -1.028  -0.862  -0.946  -1.026  -0.896
185   E        -0.892  -0.998  -0.897  -0.844  -1.022  -0.862  -0.946  -1.026  -0.896
186   V        -0.079   0.022  -0.294  -0.027   0.108  -0.386  -0.133   0.015  -0.437
187   S         1.266   1.317   1.362   1.210   1.268   1.357   1.359   1.429   1.498
188   Q        -0.431  -0.478  -0.396  -0.484  -0.545  -0.412  -0.675  -0.697  -0.585
189   I         0.573   0.427   0.365   0.601   0.414   0.289   0.545   0.295   0.160
190   L         1.266   1.317   1.362   1.238   1.310   1.384   1.359   1.429   1.498
191   P         1.266   1.317   1.362   1.289   1.359   1.433   1.359   1.429   1.498
192   W         1.266   1.317   1.362   1.492   1.559   1.629   1.359   1.429   1.498
193   K         0.573   0.502   0.374   0.645   0.566   0.350   0.545   0.423   0.178
194   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
195   V        -0.431  -0.452  -0.395  -0.591  -0.619  -0.523  -0.675  -0.672  -0.587
196   P         1.266   1.317   1.362   1.289   1.359   1.433   1.359   1.429   1.498
197   Q         0.573   0.643   0.394   0.687   0.761   0.419   0.545   0.649   0.214
198   Q         1.266   1.317   1.362   1.309   1.356   1.453   1.359   1.429   1.498
199   R         1.266   1.317   1.362   1.187   1.257   1.335   1.359   1.429   1.498
200   E         1.266   1.317   1.362   1.304   1.371   1.448   1.359   1.429   1.498
201   V         1.266   1.317   1.362   1.238   1.297   1.384   1.359   1.429   1.498
202   Y        -0.079  -0.302  -0.354   0.085  -0.255  -0.380  -0.133  -0.442  -0.522
203   V         0.573   0.427   0.365   0.613   0.401   0.297   0.545   0.295   0.160
204   L        -0.349  -0.371  -0.378  -0.428  -0.445  -0.478  -0.539  -0.546  -0.558
205   P         1.266   1.317   1.362   1.289   1.359   1.433   1.359   1.429   1.498
206   G         1.266   1.317   1.362   1.299   1.365   1.443   1.359   1.429   1.498
207   E         1.266   1.317   1.362   1.304   1.371   1.448   1.359   1.429   1.498
208   T         1.266   1.317   1.362   1.246   1.313   1.392   1.359   1.429   1.498
209   A         1.266   1.317   1.362   1.100   1.169   1.252   1.359   1.429   1.498
210   L         1.266   1.317   1.362   1.238   1.310   1.384   1.359   1.429   1.498
211   A         0.573   0.502   0.374   0.517   0.437   0.279   0.545   0.423   0.178
212   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
213   Y         1.266   1.317   1.362   1.335   1.412   1.477   1.359   1.429   1.498
214   K        -0.079  -0.186  -0.319   0.022  -0.129  -0.362  -0.133  -0.288  -0.473
215   A         1.266   1.317   1.362   1.100   1.169   1.252   1.359   1.429   1.498
216   K         0.573   0.427   0.365   0.643   0.448   0.329   0.545   0.295   0.160
217   N         1.266   1.317   1.362   1.392   1.464   1.532   1.359   1.429   1.498
218   Y        -0.892  -0.793  -0.859  -0.693  -0.541  -0.656  -0.946  -0.804  -0.855
219   S         0.573   0.502   0.374   0.589   0.484   0.296   0.545   0.423   0.178
220   D         0.255   0.334   0.292   0.166   0.302   0.202   0.003   0.132   0.024
221   K         0.255   0.334   0.292   0.186   0.319   0.225   0.003   0.132   0.024
222   D         1.266   1.317   1.362   1.259   1.336   1.404   1.359   1.429   1.498
223   I         1.266   1.317   1.362   1.223   1.315   1.370   1.359   1.429   1.498
224   I         1.266   1.317   1.362   1.223   1.315   1.370   1.359   1.429   1.498
225   G         1.266   1.317   1.362   1.299   1.365   1.443   1.359   1.429   1.498
226   M         0.573   0.427   0.365   0.796   0.583   0.467   0.545   0.295   0.160
227   A         1.266   1.317   1.362   1.100   1.169   1.252   1.359   1.429   1.498
228   T         1.266   1.317   1.362   1.246   1.313   1.392   1.359   1.429   1.498
229   Y         1.266   1.317   1.362   1.335   1.412   1.477   1.359   1.429   1.498
230   S         0.573   0.502   0.374   0.589   0.484   0.296   0.545   0.423   0.178
231   I         0.112   0.144   0.225  -0.144  -0.094   0.030  -0.268  -0.226  -0.106
232   A        -0.079   0.072  -0.271  -0.019   0.192  -0.338  -0.133   0.082  -0.404
233   P         1.266   1.317   1.362   1.289   1.359   1.433   1.359   1.429   1.498
234   G        -0.684  -0.684  -0.830  -0.537  -0.555  -0.799  -0.675  -0.663  -0.821
235   E        -1.688  -1.666  -1.580  -1.467  -1.442  -1.316  -1.353  -1.303  -1.181
236   A        -0.431  -0.309  -0.390  -0.693  -0.530  -0.603  -0.675  -0.525  -0.581
237   A         0.255   0.289   0.259  -0.007   0.034  -0.024   0.003   0.049  -0.040
238   Q        -0.431  -0.372  -0.384  -0.481  -0.411  -0.389  -0.675  -0.589  -0.574
239   Y         1.266   1.317   1.362   1.335   1.412   1.477   1.359   1.429   1.498
240   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
241   N         0.573   0.427   0.365   0.764   0.552   0.432   0.545   0.295   0.160
242   K         1.266   1.317   1.362   1.264   1.345   1.409   1.359   1.429   1.498
243   I         1.266   1.317   1.362   1.223   1.315   1.370   1.359   1.429   1.498
244   Q         1.266   1.317   1.362   1.309   1.356   1.453   1.359   1.429   1.498
245   C         1.266   1.317   1.362   1.461   1.528   1.599   1.359   1.429   1.498
246   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
247   C         1.266   1.317   1.362   1.461   1.528   1.599   1.359   1.429   1.498
248   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
249   E         1.266   1.317   1.362   1.304   1.371   1.448   1.359   1.429   1.498
250   E         1.266   1.317   1.362   1.304   1.371   1.448   1.359   1.429   1.498
251   Q         1.266   1.317   1.362   1.309   1.356   1.453   1.359   1.429   1.498
252   K        -0.431  -0.432  -0.394  -0.586  -0.564  -0.499  -0.675  -0.640  -0.583
253   L         1.266   1.317   1.362   1.238   1.310   1.384   1.359   1.429   1.498
254   A        -0.892  -0.998  -0.897  -1.025  -1.133  -0.977  -0.946  -1.026  -0.896
255   A         1.266   1.317   1.362   1.100   1.169   1.252   1.359   1.429   1.498
256   G         1.266   1.317   1.362   1.299   1.365   1.443   1.359   1.429   1.498
257   E         1.266   1.317   1.362   1.304   1.371   1.448   1.359   1.429   1.498
258   E         0.573   0.427   0.365   0.683   0.473   0.366   0.545   0.295   0.160
259   I         0.255   0.417   0.321   0.131   0.387   0.217   0.003   0.279   0.078
260   D         1.266   1.317   1.362   1.259   1.336   1.404   1.359   1.429   1.498
261   M         1.266   1.317   1.362   1.419   1.488   1.558   1.359   1.429   1.498
262   P         1.266   1.317   1.362   1.289   1.359   1.433   1.359   1.429   1.498
263   V         1.266   1.317   1.362   1.238   1.297   1.384   1.359   1.429   1.498
264   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
265   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
266   F         0.573   0.427   0.365   0.601   0.416   0.312   0.545   0.295   0.160
267   I         0.573   0.427   0.365   0.601   0.417   0.289   0.545   0.295   0.160
268   D         1.266   1.317   1.362   1.259   1.336   1.404   1.359   1.429   1.498
269   P         1.266   1.317   1.362   1.289   1.359   1.433   1.359   1.429   1.498
270   D         1.266   1.317   1.362   1.259   1.336   1.404   1.359   1.429   1.498
271   F         0.255   0.172   0.229   0.144   0.006   0.087   0.003  -0.172  -0.097
272   A         0.573   0.427   0.365   0.478   0.274   0.177   0.545   0.295   0.160
273   S        -0.892  -0.998  -0.897  -0.900  -1.017  -0.873  -0.946  -1.026  -0.896
274   D         1.266   1.317   1.362   1.259   1.336   1.404   1.359   1.429   1.498
275   P         0.573   0.427   0.365   0.667   0.461   0.350   0.545   0.295   0.160
276   A        -1.018  -0.906  -0.894  -1.118  -0.894  -0.903  -1.082  -0.934  -0.894
277   M         0.573   0.502   0.374   0.796   0.701   0.484   0.545   0.423   0.178
278   R         0.573   0.427   0.365   0.569   0.370   0.266   0.545   0.295   0.160
279   N         0.255   0.172   0.229   0.305   0.130   0.205   0.003  -0.172  -0.097
280   I         1.266   1.317   1.362   1.223   1.315   1.370   1.359   1.429   1.498
281   D        -0.349  -0.442  -0.398  -0.382  -0.529  -0.468  -0.539  -0.656  -0.590
282   D         0.573   0.427   0.365   0.638   0.439   0.325   0.545   0.295   0.160
283   I        -0.431  -0.311  -0.391  -0.596  -0.425  -0.512  -0.675  -0.527  -0.582
284   I        -0.431  -0.478  -0.396  -0.594  -0.632  -0.512  -0.675  -0.697  -0.585
285   L         1.266   1.317   1.362   1.238   1.310   1.384   1.359   1.429   1.498
286   H        -0.079  -0.170  -0.312   0.272   0.123  -0.099  -0.133  -0.268  -0.462
287   Y         1.266   1.317   1.362   1.335   1.412   1.477   1.359   1.429   1.498
288   T         0.255   0.334   0.292   0.133   0.253   0.165   0.003   0.132   0.024
289   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
290   F         1.266   1.317   1.362   1.207   1.285   1.355   1.359   1.429   1.498
291   R         0.112   0.145   0.222  -0.158  -0.103   0.015  -0.268  -0.224  -0.111
292   A         1.266   1.317   1.362   1.100   1.169   1.252   1.359   1.429   1.498
293   H        -0.349  -0.359  -0.398  -0.196  -0.267  -0.333  -0.539  -0.575  -0.590
294   Y         1.266   1.317   1.362   1.335   1.412   1.477   1.359   1.429   1.498
295   G        -1.353  -1.352  -1.273  -1.320  -1.296  -1.196  -1.217  -1.186  -1.068
296   D         1.266   1.317   1.362   1.259   1.336   1.404   1.359   1.429   1.498
297   G        -0.079  -0.302  -0.354   0.100  -0.209  -0.304  -0.133  -0.442  -0.522
298   T        -1.018  -0.885  -0.896  -1.073  -0.865  -0.876  -1.082  -0.920  -0.895
299   A        -0.557  -0.524  -0.439  -0.863  -0.796  -0.660  -0.811  -0.756  -0.641
300   V        -0.557  -0.524  -0.439  -0.826  -0.777  -0.652  -0.811  -0.756  -0.641
301   S        -0.349  -0.424  -0.387  -0.508  -0.614  -0.574  -0.539  -0.617  -0.571
302   D        -1.688  -1.666  -1.580  -1.580  -1.528  -1.432  -1.353  -1.303  -1.181
303   S        -1.353  -1.141  -1.253  -1.291  -1.006  -1.138  -1.217  -0.998  -1.051
304   K        -1.353  -1.286  -1.259  -1.411  -1.306  -1.246  -1.217  -1.134  -1.056
305   K        -1.227  -1.049  -1.222  -1.095  -0.830  -1.124  -1.082  -0.882  -1.021
306   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   S        -1.371  -1.325  -1.266  -1.344  -1.308  -1.196  -1.225  -1.157  -1.061
326   P        -0.833  -0.901  -0.896  -0.693  -0.799  -0.796  -0.856  -0.922  -0.893
327   E         0.505   0.626   0.349   0.602   0.756   0.366   0.436   0.623   0.131
328   V         0.191   0.240   0.251   0.118   0.190   0.207  -0.118  -0.041  -0.055
329   I        -0.443  -0.512  -0.427  -0.591  -0.672  -0.549  -0.671  -0.741  -0.625
330   D         0.129   0.211   0.251  -0.207  -0.075  -0.012  -0.236  -0.097  -0.055
331   T        -0.985  -0.953  -0.907  -1.077  -1.022  -0.976  -1.033  -0.980  -0.905
332   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   N        -0.985  -0.990  -0.910  -1.031  -1.086  -0.931  -1.033  -1.021  -0.908
336   S        -1.353  -1.192  -1.253  -1.470  -1.238  -1.308  -1.217  -1.034  -1.051
337   N        -1.688  -1.648  -1.569  -1.527  -1.518  -1.368  -1.353  -1.292  -1.174
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P19516
Output conservation file - output/P19516
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
