1     M         0.939   0.955   1.009   1.126   1.147   1.211   1.001   1.020   1.097
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     P        -0.825  -0.833  -0.817  -0.799  -0.788  -0.792  -0.989  -0.969  -0.939
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    N        -0.815  -0.962  -0.849  -0.743  -0.993  -0.832  -0.949  -1.144  -0.981
12    Q        -1.520  -1.546  -1.351  -1.485  -1.520  -1.269  -1.506  -1.521  -1.259
13    K        -1.784  -1.833  -1.723  -1.788  -1.862  -1.673  -1.557  -1.598  -1.410
14    S        -1.191  -1.170  -1.307  -1.023  -1.001  -1.255  -1.131  -1.111  -1.215
15    N        -1.922  -1.845  -1.714  -1.888  -1.794  -1.556  -1.700  -1.615  -1.403
16    R        -0.531  -0.782  -0.816  -0.348  -0.728  -0.797  -0.563  -0.899  -0.938
17    V        -0.165  -0.200  -0.156  -0.317  -0.379  -0.310  -0.420  -0.486  -0.445
18    Y         0.182   0.039  -0.092   0.201  -0.016  -0.245   0.148  -0.078  -0.329
19    S         0.939   0.955   1.009   1.001   1.025   1.099   1.001   1.020   1.097
20    V        -0.419  -0.420  -0.755  -0.328  -0.320  -0.797  -0.414  -0.416  -0.857
21    A         0.244   0.165  -0.071   0.410   0.310  -0.062   0.239   0.120  -0.291
22    R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
23    V         0.939   0.955   1.009   0.866   0.891   0.979   1.001   1.020   1.097
24    Y         0.244   0.135  -0.072   0.306   0.162  -0.143   0.239   0.074  -0.294
25    K        -0.723  -0.571  -0.796  -0.695  -0.450  -0.813  -0.849  -0.629  -0.912
26    N        -0.419  -0.408  -0.769  -0.295  -0.290  -0.765  -0.414  -0.404  -0.875
27    A        -0.340  -0.289  -0.167  -0.618  -0.544  -0.336  -0.740  -0.649  -0.465
28    C        -0.282  -0.189  -0.145  -0.331  -0.177  -0.123  -0.631  -0.468  -0.425
29    E        -1.043  -1.110  -1.286  -0.788  -0.890  -1.142  -0.958  -1.038  -1.193
30    E        -1.500  -1.427  -1.336  -1.588  -1.507  -1.327  -1.502  -1.427  -1.245
31    R        -0.860  -0.803  -0.830  -0.870  -0.775  -0.826  -1.067  -1.004  -0.960
32    P         0.939   0.955   1.009   1.033   1.062   1.127   1.001   1.020   1.097
33    Q        -0.980  -0.951  -0.844  -0.953  -0.928  -0.774  -1.175  -1.135  -0.974
34    E        -0.419  -0.588  -0.778  -0.214  -0.442  -0.728  -0.414  -0.636  -0.888
35    Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
36    W         0.939   0.955   1.009   1.175   1.193   1.254   1.001   1.020   1.097
37    D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
38    Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
39    E        -0.099  -0.187  -0.147  -0.158  -0.335  -0.298  -0.305  -0.464  -0.429
40    Q        -1.379  -1.321  -1.313  -1.274  -1.184  -1.144  -1.393  -1.316  -1.223
41    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    V        -1.300  -1.368  -1.315  -1.261  -1.353  -1.265  -1.284  -1.327  -1.223
43    T        -1.820  -1.828  -1.709  -1.627  -1.599  -1.445  -1.611  -1.590  -1.399
44    I         0.244   0.165  -0.071   0.268   0.163  -0.187   0.239   0.120  -0.291
45    D        -2.140  -2.173  -2.035  -1.932  -1.988  -1.765  -1.720  -1.733  -1.517
46    W         0.244   0.165  -0.071   0.574   0.469   0.077   0.239   0.120  -0.291
47    G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
48    K        -2.140  -2.173  -2.035  -2.128  -2.189  -1.978  -1.720  -1.733  -1.517
49    I        -0.419  -0.562  -0.781  -0.350  -0.553  -0.904  -0.414  -0.600  -0.891
50    S        -1.500  -1.501  -1.339  -1.640  -1.628  -1.394  -1.502  -1.481  -1.248
51    N         0.939   0.955   1.009   0.980   1.013   1.080   1.001   1.020   1.097
52    Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
53    E         0.939   0.955   1.009   0.970   0.988   1.072   1.001   1.020   1.097
54    I        -0.099  -0.109  -0.144  -0.255  -0.282  -0.372  -0.305  -0.326  -0.424
55    I        -0.860  -0.909  -0.819  -1.106  -1.167  -1.003  -1.067  -1.098  -0.947
56    N        -1.820  -1.597  -1.703  -1.686  -1.354  -1.521  -1.611  -1.378  -1.394
57    K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
58    I         0.244   0.165  -0.071   0.253   0.145  -0.229   0.239   0.120  -0.291
59    G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
60    R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
61    G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
62    K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
63    Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
64    S         0.939   0.955   1.009   1.001   1.053   1.100   1.001   1.020   1.097
65    E         0.939   0.955   1.009   0.970   0.988   1.072   1.001   1.020   1.097
66    V         0.244   0.135  -0.072   0.265   0.128  -0.180   0.239   0.074  -0.294
67    F         0.939   0.955   1.009   1.023   1.038   1.119   1.001   1.020   1.097
68    S        -1.500  -1.430  -1.335  -1.494  -1.388  -1.276  -1.502  -1.419  -1.243
69    G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
70    R        -1.940  -1.892  -1.717  -2.180  -2.120  -1.818  -1.720  -1.656  -1.406
71    C        -0.860  -0.801  -0.826  -0.799  -0.707  -0.722  -1.067  -0.987  -0.955
72    I        -0.282  -0.165  -0.145  -0.600  -0.385  -0.375  -0.631  -0.425  -0.424
73    V        -1.379  -1.224  -1.305  -1.598  -1.408  -1.407  -1.393  -1.239  -1.216
74    N         0.939   0.955   1.009   0.980   1.013   1.080   1.001   1.020   1.097
75    N        -1.300  -1.417  -1.323  -1.355  -1.541  -1.399  -1.284  -1.390  -1.232
76    Q        -1.300  -1.256  -1.305  -1.162  -1.071  -1.198  -1.284  -1.210  -1.213
77    K        -0.860  -0.923  -0.829  -0.975  -1.056  -0.897  -1.067  -1.121  -0.958
78    C         0.939   0.955   1.009   1.194   1.214   1.271   1.001   1.020   1.097
79    V         0.244   0.165  -0.071   0.245   0.143  -0.233   0.239   0.120  -0.291
80    I         0.939   0.955   1.009   0.876   0.893   0.988   1.001   1.020   1.097
81    K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
82    V         0.939   0.955   1.009   0.866   0.891   0.979   1.001   1.020   1.097
83    L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
84    K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
85    P         0.939   0.955   1.009   1.033   1.062   1.127   1.001   1.020   1.097
86    V         0.939   0.955   1.009   0.866   0.891   0.979   1.001   1.020   1.097
87    K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
88    M        -1.300  -1.350  -1.324  -1.216  -1.344  -1.362  -1.284  -1.342  -1.234
89    K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
90    K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
91    I         0.939   0.955   1.009   0.876   0.893   0.988   1.001   1.020   1.097
92    Y        -0.282  -0.310  -0.172  -0.598  -0.679  -0.444  -0.631  -0.690  -0.475
93    R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
94    E         0.939   0.955   1.009   0.970   0.988   1.072   1.001   1.020   1.097
95    L        -1.059  -0.959  -0.848  -1.492  -1.310  -1.127  -1.284  -1.148  -0.980
96    K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
97    I         0.244   0.295  -0.064   0.253   0.317  -0.216   0.239   0.313  -0.279
98    L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
99    T        -0.860  -0.711  -0.815  -0.836  -0.608  -0.784  -1.067  -0.869  -0.939
100   N         0.939   0.955   1.009   0.980   1.013   1.080   1.001   1.020   1.097
101   L         0.244   0.135  -0.072   0.132  -0.013  -0.333   0.239   0.074  -0.294
102   T        -0.282  -0.310  -0.172  -0.332  -0.407  -0.196  -0.631  -0.690  -0.475
103   G         0.244   0.135  -0.072   0.408   0.261  -0.064   0.239   0.074  -0.294
104   G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
105   P         0.939   0.955   1.009   1.033   1.062   1.127   1.001   1.020   1.097
106   N         0.939   0.955   1.009   0.980   1.013   1.080   1.001   1.020   1.097
107   V        -0.282  -0.165  -0.145  -0.597  -0.384  -0.372  -0.631  -0.425  -0.424
108   V        -0.282  -0.289  -0.170  -0.597  -0.628  -0.425  -0.631  -0.651  -0.471
109   G        -0.723  -0.852  -0.831  -0.638  -0.841  -0.816  -0.849  -1.023  -0.961
110   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
111   Y         0.244   0.348  -0.059   0.138   0.268  -0.292   0.239   0.387  -0.271
112   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
113   I        -0.282  -0.293  -0.169  -0.597  -0.636  -0.423  -0.631  -0.658  -0.469
114   V         0.939   0.955   1.009   0.866   0.891   0.979   1.001   1.020   1.097
115   Q        -0.282  -0.189  -0.145  -0.395  -0.244  -0.188  -0.631  -0.468  -0.425
116   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
117   A        -1.820  -1.674  -1.691  -1.616  -1.394  -1.419  -1.611  -1.455  -1.383
118   D        -2.580  -2.486  -2.297  -2.379  -2.257  -2.016  -1.937  -1.850  -1.592
119   S         0.244   0.135  -0.072   0.395   0.286  -0.084   0.239   0.074  -0.294
120   K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
121   I        -0.282  -0.310  -0.172  -0.476  -0.515  -0.284  -0.631  -0.690  -0.475
122   P         0.939   0.955   1.009   1.033   1.062   1.127   1.001   1.020   1.097
123   A        -0.282  -0.310  -0.172  -0.404  -0.456  -0.253  -0.631  -0.690  -0.475
124   L         0.244   0.323  -0.055   0.156   0.253  -0.237   0.239   0.351  -0.263
125   I         0.939   0.955   1.009   0.876   0.893   0.988   1.001   1.020   1.097
126   F         0.939   0.955   1.009   1.023   1.038   1.119   1.001   1.020   1.097
127   E         0.939   0.955   1.009   0.970   0.988   1.072   1.001   1.020   1.097
128   E        -1.820  -1.772  -1.717  -1.769  -1.731  -1.625  -1.611  -1.561  -1.406
129   I         0.244   0.348  -0.059   0.245   0.378  -0.212   0.239   0.387  -0.271
130   K        -1.379  -1.458  -1.330  -1.507  -1.585  -1.387  -1.393  -1.439  -1.238
131   N         0.939   0.955   1.009   0.980   1.013   1.080   1.001   1.020   1.097
132   V        -1.043  -1.079  -1.286  -0.908  -0.970  -1.249  -0.958  -1.001  -1.193
133   D         0.244   0.177  -0.063   0.274   0.180  -0.168   0.239   0.139  -0.277
134   F         0.939   0.955   1.009   1.023   1.038   1.119   1.001   1.020   1.097
135   R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
136   T        -0.723  -0.727  -0.801  -0.604  -0.570  -0.745  -0.849  -0.827  -0.919
137   L         0.244   0.135  -0.072   0.132  -0.013  -0.333   0.239   0.074  -0.294
138   Y         0.244   0.135  -0.072   0.306   0.162  -0.143   0.239   0.074  -0.294
139   P         0.939   0.955   1.009   1.033   1.062   1.127   1.001   1.020   1.097
140   T        -1.500  -1.485  -1.334  -1.576  -1.521  -1.285  -1.502  -1.461  -1.243
141   F         0.244   0.165  -0.071   0.385   0.269  -0.150   0.239   0.120  -0.291
142   K        -1.300  -1.408  -1.322  -1.181  -1.337  -1.262  -1.284  -1.383  -1.232
143   L        -1.059  -0.959  -0.848  -1.483  -1.309  -1.118  -1.284  -1.148  -0.980
144   P        -2.260  -2.130  -2.026  -2.103  -1.923  -1.761  -1.828  -1.707  -1.511
145   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
146   I        -1.043  -0.972  -1.272  -0.951  -0.864  -1.322  -0.958  -0.874  -1.177
147   Q        -0.282  -0.310  -0.172  -0.370  -0.450  -0.231  -0.631  -0.690  -0.475
148   Y         0.244   0.295  -0.064   0.306   0.366  -0.129   0.239   0.313  -0.279
149   Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
150   F        -0.723  -0.857  -0.832  -0.674  -0.911  -0.879  -0.849  -1.027  -0.961
151   T        -0.723  -0.852  -0.831  -0.597  -0.828  -0.814  -0.849  -1.023  -0.961
152   Q        -0.099  -0.173  -0.144  -0.043  -0.181  -0.178  -0.305  -0.439  -0.423
153   L         0.244   0.135  -0.072   0.132  -0.013  -0.333   0.239   0.074  -0.294
154   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
155   I        -1.300  -1.380  -1.328  -1.383  -1.540  -1.404  -1.284  -1.367  -1.237
156   A         0.939   0.955   1.009   1.013   1.029   1.110   1.001   1.020   1.097
157   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
158   D         0.244   0.135  -0.072   0.274   0.123  -0.185   0.239   0.074  -0.294
159   Y        -0.099  -0.173  -0.144  -0.174  -0.308  -0.265  -0.305  -0.439  -0.423
160   C        -0.282  -0.256  -0.163  -0.246  -0.193  -0.107  -0.631  -0.588  -0.458
161   H         0.939   0.955   1.009   1.127   1.145   1.212   1.001   1.020   1.097
162   S         0.939   0.955   1.009   1.001   1.053   1.100   1.001   1.020   1.097
163   M        -0.723  -0.857  -0.832  -0.600  -0.839  -0.848  -0.849  -1.027  -0.961
164   G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
165   I         0.939   0.955   1.009   0.876   0.893   0.988   1.001   1.020   1.097
166   M        -0.099   0.014  -0.105  -0.007   0.188  -0.087  -0.305  -0.118  -0.352
167   H         0.939   0.955   1.009   1.127   1.145   1.212   1.001   1.020   1.097
168   R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
169   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
170   V         0.939   0.955   1.009   0.866   0.891   0.979   1.001   1.020   1.097
171   K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
172   P         0.939   0.955   1.009   1.033   1.062   1.127   1.001   1.020   1.097
173   Q        -0.282  -0.310  -0.172  -0.298  -0.354  -0.143  -0.631  -0.690  -0.475
174   N         0.939   0.955   1.009   0.980   1.013   1.080   1.001   1.020   1.097
175   V        -0.322  -0.301  -0.170  -0.685  -0.655  -0.430  -0.705  -0.673  -0.471
176   M         0.939   0.955   1.009   1.126   1.147   1.211   1.001   1.020   1.097
177   I         0.182   0.041  -0.089   0.171  -0.030  -0.254   0.148  -0.074  -0.324
178   D         0.939   0.955   1.009   0.884   0.905   0.995   1.001   1.020   1.097
179   P         0.182   0.039  -0.092   0.368   0.180  -0.034   0.148  -0.078  -0.329
180   T        -2.654  -2.548  -2.308  -2.440  -2.326  -1.959  -1.984  -1.889  -1.598
181   E        -2.288  -2.237  -2.040  -2.089  -2.071  -1.745  -1.842  -1.785  -1.520
182   R        -0.915  -0.964  -0.835  -1.121  -1.155  -0.941  -1.131  -1.160  -0.965
183   K         0.939   0.955   1.009   0.805   0.840   0.926   1.001   1.020   1.097
184   L         0.244   0.135  -0.072   0.132  -0.013  -0.333   0.239   0.074  -0.294
185   R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
186   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
187   I         0.939   0.955   1.009   0.876   0.893   0.988   1.001   1.020   1.097
188   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
189   W         0.939   0.955   1.009   1.175   1.193   1.254   1.001   1.020   1.097
190   G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
191   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
192   A         0.939   0.955   1.009   1.013   1.029   1.110   1.001   1.020   1.097
193   E         0.939   0.955   1.009   0.970   0.988   1.072   1.001   1.020   1.097
194   F         0.939   0.955   1.009   1.023   1.038   1.119   1.001   1.020   1.097
195   Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
196   H         0.939   0.955   1.009   1.127   1.145   1.212   1.001   1.020   1.097
197   P        -0.980  -0.983  -0.858  -1.002  -0.997  -0.842  -1.175  -1.172  -0.992
198   G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
199   V        -1.059  -1.051  -0.861  -1.138  -1.093  -0.819  -1.284  -1.262  -0.995
200   D        -0.723  -0.869  -0.832  -0.790  -1.036  -0.959  -0.849  -1.038  -0.960
201   Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
202   N         0.939   0.955   1.009   0.980   1.013   1.080   1.001   1.020   1.097
203   V         0.244   0.295  -0.064   0.245   0.314  -0.220   0.239   0.313  -0.279
204   R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
205   V         0.939   0.955   1.009   0.866   0.891   0.979   1.001   1.020   1.097
206   A         0.939   0.955   1.009   1.013   1.029   1.110   1.001   1.020   1.097
207   S         0.939   0.955   1.009   1.001   1.053   1.100   1.001   1.020   1.097
208   R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
209   Y         0.244   0.135  -0.072   0.332   0.198  -0.073   0.239   0.074  -0.294
210   H        -0.723  -0.869  -0.832  -0.540  -0.792  -0.769  -0.849  -1.038  -0.960
211   K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
212   G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
213   P         0.939   0.955   1.009   1.033   1.062   1.127   1.001   1.020   1.097
214   E         0.939   0.955   1.009   0.970   0.988   1.072   1.001   1.020   1.097
215   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
216   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
217   V        -0.419  -0.459  -0.765  -0.366  -0.427  -0.900  -0.414  -0.471  -0.870
218   N        -0.860  -0.821  -0.831  -0.989  -0.955  -0.912  -1.067  -1.019  -0.961
219   L        -0.099  -0.173  -0.144  -0.320  -0.445  -0.377  -0.305  -0.439  -0.423
220   N        -0.860  -0.859  -0.824  -0.868  -0.827  -0.789  -1.067  -1.029  -0.950
221   Q        -0.099  -0.173  -0.144  -0.043  -0.181  -0.178  -0.305  -0.439  -0.423
222   Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
223   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
224   Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
225   S         0.939   0.955   1.009   1.001   1.053   1.100   1.001   1.020   1.097
226   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
227   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
228   L        -0.419  -0.562  -0.781  -0.438  -0.625  -0.918  -0.414  -0.600  -0.891
229   W         0.939   0.955   1.009   1.175   1.193   1.254   1.001   1.020   1.097
230   S         0.244   0.295  -0.064   0.400   0.495  -0.055   0.239   0.313  -0.279
231   V        -0.723  -0.857  -0.832  -0.865  -1.106  -1.040  -0.849  -1.027  -0.961
232   G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
233   C        -0.419  -0.562  -0.781  -0.025  -0.228  -0.642  -0.414  -0.600  -0.891
234   M         0.244   0.135  -0.072   0.536   0.412   0.061   0.239   0.074  -0.294
235   L        -0.723  -0.748  -0.817  -0.896  -0.954  -1.008  -0.849  -0.901  -0.941
236   A         0.244   0.323  -0.055   0.411   0.503  -0.031   0.239   0.351  -0.263
237   A        -0.419  -0.588  -0.778  -0.182  -0.411  -0.721  -0.414  -0.636  -0.888
238   I        -0.419  -0.562  -0.781  -0.338  -0.536  -0.876  -0.414  -0.600  -0.891
239   V        -0.099  -0.009  -0.119  -0.255  -0.113  -0.321  -0.305  -0.156  -0.377
240   F         0.939   0.955   1.009   1.023   1.038   1.119   1.001   1.020   1.097
241   K        -0.099  -0.187  -0.147  -0.276  -0.419  -0.359  -0.305  -0.464  -0.429
242   K         0.939   0.955   1.009   0.813   0.847   0.932   1.001   1.020   1.097
243   E        -0.099  -0.193  -0.157  -0.158  -0.346  -0.319  -0.305  -0.474  -0.446
244   P         0.244   0.165  -0.071   0.442   0.355  -0.012   0.239   0.120  -0.291
245   F         0.244   0.323  -0.055   0.385   0.482  -0.117   0.239   0.351  -0.263
246   F         0.939   0.955   1.009   1.023   1.038   1.119   1.001   1.020   1.097
247   K        -1.059  -1.051  -0.861  -1.249  -1.205  -0.906  -1.284  -1.262  -0.995
248   G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
249   S        -1.300  -1.340  -1.314  -1.216  -1.223  -1.225  -1.284  -1.297  -1.222
250   S        -0.419  -0.456  -0.772  -0.199  -0.229  -0.734  -0.414  -0.463  -0.879
251   N         0.939   0.955   1.009   0.980   1.013   1.080   1.001   1.020   1.097
252   P        -2.260  -2.274  -2.040  -2.026  -2.031  -1.709  -1.828  -1.809  -1.520
253   D         0.244   0.135  -0.072   0.276   0.128  -0.181   0.239   0.074  -0.294
254   Q         0.939   0.955   1.009   1.060   1.082   1.152   1.001   1.020   1.097
255   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
256   V         0.939   0.955   1.009   0.866   0.891   0.979   1.001   1.020   1.097
257   K        -0.723  -0.727  -0.801  -0.808  -0.787  -0.892  -0.849  -0.827  -0.919
258   I         0.939   0.955   1.009   0.876   0.893   0.988   1.001   1.020   1.097
259   A         0.939   0.955   1.009   1.013   1.029   1.110   1.001   1.020   1.097
260   T        -0.419  -0.218  -0.755  -0.387  -0.125  -0.850  -0.414  -0.152  -0.857
261   V         0.939   0.955   1.009   0.866   0.891   0.979   1.001   1.020   1.097
262   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
263   G         0.939   0.955   1.009   1.009   1.025   1.107   1.001   1.020   1.097
264   T         0.939   0.955   1.009   1.089   1.116   1.178   1.001   1.020   1.097
265   K        -1.820  -1.816  -1.716  -1.856  -1.843  -1.637  -1.611  -1.594  -1.404
266   E        -0.723  -0.670  -0.812  -0.726  -0.674  -0.885  -0.849  -0.788  -0.936
267   L         0.244   0.135  -0.072   0.172   0.043  -0.221   0.239   0.074  -0.294
268   L        -1.500  -1.445  -1.329  -1.540  -1.430  -1.288  -1.502  -1.411  -1.238
269   G        -2.260  -2.163  -2.022  -2.209  -2.096  -1.853  -1.828  -1.735  -1.508
270   Y         0.244   0.135  -0.072   0.332   0.198  -0.073   0.239   0.074  -0.294
271   L        -0.282  -0.246  -0.163  -0.705  -0.645  -0.497  -0.631  -0.571  -0.457
272   G        -2.580  -2.545  -2.306  -2.300  -2.247  -1.927  -1.937  -1.888  -1.597
273   K         0.244   0.295  -0.064   0.229   0.306  -0.162   0.239   0.313  -0.279
274   Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
275   G        -0.419  -0.562  -0.781  -0.182  -0.379  -0.721  -0.414  -0.600  -0.891
276   L        -0.340  -0.312  -0.172  -0.802  -0.758  -0.502  -0.740  -0.693  -0.475
277   H        -1.620  -1.632  -1.690  -1.539  -1.572  -1.630  -1.393  -1.397  -1.383
278   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
279   P        -0.980  -0.951  -0.844  -1.056  -1.022  -0.882  -1.175  -1.135  -0.974
280   S        -1.500  -1.529  -1.338  -1.533  -1.570  -1.288  -1.502  -1.508  -1.247
281   E        -0.723  -0.869  -0.832  -0.678  -0.912  -0.865  -0.849  -1.038  -0.960
282   Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
283   D        -0.099  -0.133  -0.153  -0.212  -0.279  -0.322  -0.305  -0.369  -0.440
284   N        -1.300  -1.131  -1.298  -1.260  -1.054  -1.211  -1.284  -1.103  -1.208
285   I         0.939   0.955   1.009   0.876   0.893   0.988   1.001   1.020   1.097
286   M        -0.282  -0.189  -0.145  -0.559  -0.414  -0.322  -0.631  -0.468  -0.425
287   R        -0.723  -0.571  -0.796  -0.680  -0.449  -0.835  -0.849  -0.629  -0.912
288   D        -1.820  -1.900  -1.718  -1.688  -1.763  -1.502  -1.611  -1.650  -1.406
289   F        -0.282  -0.232  -0.158  -0.486  -0.412  -0.288  -0.631  -0.546  -0.448
290   T        -1.300  -1.232  -1.301  -1.101  -0.979  -1.103  -1.284  -1.180  -1.209
291   K        -0.099  -0.090  -0.149  -0.163  -0.158  -0.324  -0.305  -0.294  -0.432
292   K        -0.419  -0.599  -0.784  -0.374  -0.600  -0.862  -0.414  -0.651  -0.895
293   S        -0.419  -0.408  -0.769  -0.183  -0.171  -0.739  -0.414  -0.404  -0.875
294   W         0.939   0.955   1.009   1.175   1.193   1.254   1.001   1.020   1.097
295   T        -2.260  -2.218  -2.027  -2.058  -1.986  -1.726  -1.828  -1.771  -1.512
296   H        -2.260  -2.167  -2.036  -2.003  -1.890  -1.722  -1.828  -1.733  -1.517
297   F         0.939   0.955   1.009   1.023   1.038   1.119   1.001   1.020   1.097
298   I        -0.860  -0.822  -0.819  -1.083  -1.048  -0.964  -1.067  -1.022  -0.948
299   T        -0.282  -0.247  -0.163  -0.387  -0.319  -0.207  -0.631  -0.573  -0.458
300   S        -1.620  -1.649  -1.688  -1.354  -1.383  -1.498  -1.393  -1.413  -1.380
301   E        -1.820  -1.775  -1.705  -1.806  -1.752  -1.621  -1.611  -1.557  -1.396
302   T        -0.340  -0.312  -0.172  -0.481  -0.428  -0.218  -0.740  -0.693  -0.475
303   -        -0.303  -0.266  -0.167  -0.424  -0.366  -0.229  -0.671  -0.608  -0.465
304   K        -2.260  -2.274  -2.040  -1.977  -1.987  -1.704  -1.828  -1.809  -1.520
305   L        -0.419  -0.588  -0.778  -0.457  -0.693  -0.959  -0.414  -0.636  -0.888
306   A        -0.723  -0.692  -0.792  -0.709  -0.645  -0.854  -0.849  -0.781  -0.907
307   V        -1.059  -1.052  -0.862  -1.273  -1.226  -0.953  -1.284  -1.263  -0.997
308   P        -1.379  -1.336  -1.312  -1.395  -1.340  -1.263  -1.393  -1.337  -1.222
309   E        -0.419  -0.418  -0.769  -0.233  -0.236  -0.758  -0.414  -0.422  -0.875
310   V        -1.500  -1.319  -1.332  -1.662  -1.353  -1.430  -1.502  -1.296  -1.241
311   V        -0.860  -0.720  -0.810  -1.138  -0.901  -1.043  -1.067  -0.868  -0.934
312   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
313   L        -0.282  -0.288  -0.170  -0.618  -0.632  -0.408  -0.631  -0.648  -0.470
314   I        -0.860  -0.774  -0.830  -1.185  -1.110  -1.108  -1.067  -0.979  -0.960
315   D         0.244   0.165  -0.071   0.276   0.168  -0.178   0.239   0.120  -0.291
316   N        -1.500  -1.389  -1.328  -1.565  -1.425  -1.281  -1.502  -1.378  -1.237
317   L         0.244   0.135  -0.072   0.134  -0.012  -0.328   0.239   0.074  -0.294
318   L         0.939   0.955   1.009   0.755   0.777   0.881   1.001   1.020   1.097
319   R        -0.099   0.014  -0.105  -0.075   0.090  -0.104  -0.305  -0.118  -0.352
320   Y         0.939   0.955   1.009   0.906   0.923   1.015   1.001   1.020   1.097
321   D         0.939   0.955   1.009   0.882   0.893   0.994   1.001   1.020   1.097
322   H         0.939   0.955   1.009   1.127   1.145   1.212   1.001   1.020   1.097
323   Q         0.244   0.177  -0.063   0.453   0.372  -0.018   0.239   0.139  -0.277
324   E        -0.099   0.014  -0.105  -0.198  -0.012  -0.267  -0.305  -0.118  -0.352
325   R         0.939   0.955   1.009   0.987   1.002   1.087   1.001   1.020   1.097
326   L        -0.099   0.014  -0.105  -0.316  -0.145  -0.313  -0.305  -0.118  -0.352
327   T         0.939   0.955   1.009   1.089   1.116   1.178   1.001   1.020   1.097
328   A         0.244   0.165  -0.071   0.438   0.340   0.015   0.239   0.120  -0.291
329   K        -0.723  -0.794  -0.817  -0.819  -0.905  -0.913  -0.849  -0.931  -0.943
330   E         0.939   0.955   1.009   0.970   0.988   1.072   1.001   1.020   1.097
331   A         0.939   0.955   1.009   1.013   1.029   1.110   1.001   1.020   1.097
332   M         0.939   0.955   1.009   1.127   1.161   1.212   1.001   1.020   1.097
333   D        -0.980  -0.974  -0.849  -1.143  -1.150  -0.937  -1.175  -1.164  -0.981
334   H         0.939   0.955   1.009   1.127   1.145   1.212   1.001   1.020   1.097
335   K        -0.980  -0.921  -0.849  -1.098  -0.987  -0.934  -1.175  -1.090  -0.981
336   F        -0.282  -0.310  -0.172  -0.445  -0.538  -0.306  -0.631  -0.690  -0.475
337   F         0.939   0.955   1.009   1.023   1.038   1.119   1.001   1.020   1.097
338   K        -1.620  -1.729  -1.705  -1.489  -1.654  -1.566  -1.393  -1.494  -1.395
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   T        -1.922  -1.864  -1.719  -1.851  -1.794  -1.563  -1.700  -1.628  -1.407
354   K        -1.922  -1.911  -1.716  -1.981  -1.941  -1.657  -1.700  -1.665  -1.404
355   F        -1.784  -1.868  -1.723  -1.592  -1.770  -1.551  -1.557  -1.621  -1.410
356   E        -2.288  -2.198  -2.032  -2.159  -2.023  -1.810  -1.842  -1.753  -1.515
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P19454
Output conservation file - output/P19454
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
