1     M         0.963   0.989   1.032   1.071   1.112   1.166   1.012   1.047   1.109
2     L        -1.291  -1.224  -1.294  -1.226  -1.155  -1.197  -1.259  -1.208  -1.194
3     A        -1.291  -1.236  -1.284  -1.292  -1.228  -1.307  -1.259  -1.208  -1.185
4     A        -1.814  -1.760  -1.676  -1.881  -1.811  -1.629  -1.584  -1.520  -1.357
5     S        -1.814  -1.742  -1.673  -1.848  -1.697  -1.572  -1.584  -1.491  -1.354
6     F        -2.136  -2.021  -1.986  -2.046  -1.908  -1.791  -1.692  -1.581  -1.462
7     K        -1.491  -1.375  -1.305  -1.508  -1.353  -1.202  -1.476  -1.342  -1.204
8     R        -1.814  -1.816  -1.682  -1.680  -1.689  -1.465  -1.584  -1.553  -1.360
9     Q        -2.257  -2.183  -1.999  -2.045  -2.016  -1.710  -1.800  -1.710  -1.472
10    P        -1.508  -1.330  -1.306  -1.496  -1.234  -1.171  -1.488  -1.281  -1.205
11    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    V        -0.916  -0.812  -0.810  -1.175  -0.987  -1.012  -1.103  -0.950  -0.931
17    R        -0.220  -0.141  -0.135  -0.353  -0.232  -0.249  -0.526  -0.396  -0.424
18    G        -0.649  -0.729  -0.803  -0.823  -1.001  -1.106  -0.719  -0.843  -0.921
19    L        -2.367  -2.235  -2.016  -2.393  -2.172  -1.887  -1.872  -1.737  -1.483
20    G        -1.512  -1.475  -1.319  -1.714  -1.655  -1.394  -1.480  -1.424  -1.216
21    A        -0.803  -0.650  -0.794  -1.039  -0.805  -1.015  -0.926  -0.714  -0.910
22    V        -1.937  -1.786  -1.684  -1.893  -1.697  -1.541  -1.680  -1.517  -1.362
23    L        -0.997  -0.896  -0.819  -1.114  -0.937  -0.828  -1.203  -1.061  -0.943
24    R        -0.649  -0.689  -0.775  -0.580  -0.654  -0.829  -0.719  -0.774  -0.885
25    T        -0.916  -0.773  -0.799  -1.066  -0.847  -0.881  -1.103  -0.911  -0.919
26    P        -1.512  -1.458  -1.306  -1.548  -1.487  -1.254  -1.480  -1.404  -1.204
27    T        -2.028  -1.944  -1.706  -1.997  -1.882  -1.538  -1.757  -1.653  -1.379
28    R        -0.997  -0.953  -0.816  -1.012  -0.940  -0.738  -1.203  -1.131  -0.939
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    I        -1.937  -1.754  -1.688  -1.896  -1.640  -1.532  -1.680  -1.487  -1.365
33    G        -0.916  -0.846  -0.815  -1.161  -1.058  -0.960  -1.103  -1.023  -0.939
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    H        -2.257  -2.068  -1.993  -2.200  -2.002  -1.749  -1.800  -1.629  -1.468
36    V        -1.814  -1.775  -1.679  -1.788  -1.757  -1.629  -1.584  -1.531  -1.359
37    R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
38    T        -1.491  -1.533  -1.313  -1.643  -1.694  -1.378  -1.476  -1.479  -1.212
39    M        -1.291  -1.276  -1.296  -1.152  -1.188  -1.208  -1.259  -1.254  -1.196
40    A        -0.969  -0.980  -0.835  -1.275  -1.272  -1.027  -1.151  -1.161  -0.962
41    T        -1.181  -0.945  -1.259  -0.982  -0.657  -1.135  -1.107  -0.822  -1.156
42    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    T        -1.512  -1.387  -1.302  -1.642  -1.465  -1.356  -1.480  -1.330  -1.200
45    T        -1.512  -1.387  -1.302  -1.634  -1.424  -1.347  -1.480  -1.330  -1.200
46    D        -0.997  -0.969  -0.817  -1.203  -1.158  -0.949  -1.203  -1.146  -0.941
47    K        -1.512  -1.419  -1.307  -1.469  -1.338  -1.210  -1.480  -1.369  -1.205
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
53    K        -2.367  -2.254  -2.016  -2.240  -2.102  -1.752  -1.872  -1.753  -1.483
54    A        -1.508  -1.338  -1.303  -1.655  -1.370  -1.333  -1.488  -1.298  -1.203
55    P        -0.916  -0.901  -0.819  -0.956  -0.972  -0.830  -1.103  -1.078  -0.943
56    E        -1.935  -1.857  -1.687  -2.106  -1.967  -1.726  -1.692  -1.591  -1.365
57    D        -1.935  -1.887  -1.690  -1.979  -1.871  -1.585  -1.692  -1.617  -1.367
58    I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    S        -1.370  -1.284  -1.282  -1.330  -1.188  -1.151  -1.367  -1.255  -1.182
62    D        -0.969  -0.988  -0.836  -1.079  -1.135  -0.921  -1.151  -1.170  -0.963
63    T        -1.814  -1.669  -1.680  -1.676  -1.482  -1.457  -1.584  -1.446  -1.360
64    V        -0.710  -0.804  -0.807  -0.613  -0.771  -0.712  -0.827  -0.968  -0.930
65    Q        -1.814  -1.747  -1.675  -1.579  -1.493  -1.416  -1.584  -1.507  -1.356
66    I        -0.082  -0.206  -0.140  -0.084  -0.329  -0.237  -0.286  -0.512  -0.432
67    E        -1.935  -1.774  -1.687  -1.935  -1.712  -1.561  -1.692  -1.534  -1.365
68    L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
69    P        -1.032  -1.254  -1.289  -0.716  -1.050  -1.167  -0.935  -1.182  -1.187
70    E        -0.710  -0.748  -0.804  -0.766  -0.861  -0.943  -0.827  -0.911  -0.926
71    S        -1.291  -1.252  -1.278  -1.248  -1.166  -1.226  -1.259  -1.179  -1.177
72    S         0.263   0.068  -0.061   0.332   0.079  -0.148   0.255  -0.045  -0.290
73    F        -0.082  -0.027  -0.114  -0.019   0.068  -0.128  -0.286  -0.200  -0.386
74    E         0.263   0.274  -0.042   0.313   0.324  -0.121   0.255   0.270  -0.257
75    S        -0.710  -0.630  -0.786  -0.874  -0.790  -0.955  -0.827  -0.747  -0.902
76    Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
77    M        -1.814  -1.838  -1.687  -1.606  -1.665  -1.478  -1.584  -1.574  -1.365
78    L         0.263   0.068  -0.061   0.305   0.049  -0.154   0.255  -0.045  -0.290
79    E        -0.325  -0.249  -0.134  -0.574  -0.424  -0.249  -0.719  -0.588  -0.421
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    P        -0.847  -0.751  -0.794  -0.854  -0.754  -0.758  -1.043  -0.934  -0.915
82    P         0.963   0.989   1.032   1.080   1.113   1.174   1.012   1.047   1.109
83    D        -1.935  -1.786  -1.686  -1.937  -1.718  -1.582  -1.692  -1.543  -1.365
84    L        -0.404  -0.656  -0.776  -0.292  -0.639  -0.829  -0.394  -0.726  -0.886
85    S        -1.291  -1.297  -1.296  -1.249  -1.306  -1.234  -1.259  -1.272  -1.196
86    Y        -1.370  -1.468  -1.303  -1.294  -1.415  -1.189  -1.367  -1.420  -1.202
87    E        -1.032  -0.907  -1.249  -0.825  -0.673  -1.115  -0.935  -0.789  -1.146
88    T        -1.291  -1.258  -1.295  -1.233  -1.232  -1.274  -1.259  -1.239  -1.195
89    S        -0.710  -0.497  -0.762  -0.696  -0.389  -0.798  -0.827  -0.541  -0.870
90    K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
91    A        -2.136  -1.926  -1.978  -2.175  -1.863  -1.955  -1.692  -1.487  -1.457
92    T        -1.370  -1.161  -1.284  -1.379  -1.113  -1.211  -1.367  -1.136  -1.184
93    L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
94    L         0.263   0.194  -0.049   0.293   0.213  -0.168   0.255   0.152  -0.270
95    Q        -0.404  -0.522  -0.759  -0.127  -0.328  -0.753  -0.394  -0.561  -0.864
96    M         0.263   0.068  -0.061   0.454   0.187  -0.068   0.255  -0.045  -0.290
97    Y         0.263   0.407  -0.034   0.404   0.579  -0.012   0.255   0.456  -0.243
98    K        -0.404  -0.656  -0.776  -0.273  -0.627  -0.840  -0.394  -0.726  -0.886
99    D         0.263   0.068  -0.061   0.413   0.157  -0.092   0.255  -0.045  -0.290
100   M         0.963   0.989   1.032   1.071   1.112   1.166   1.012   1.047   1.109
101   V        -0.266  -0.155  -0.124  -0.435  -0.255  -0.216  -0.610  -0.420  -0.404
102   I        -0.710  -0.843  -0.808  -0.641  -0.877  -0.818  -0.827  -1.001  -0.930
103   I        -0.266  -0.238  -0.144  -0.417  -0.392  -0.248  -0.610  -0.570  -0.441
104   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
105   R         0.263   0.194  -0.049   0.406   0.327  -0.025   0.255   0.152  -0.270
106   M        -0.082  -0.178  -0.134  -0.053  -0.240  -0.222  -0.286  -0.461  -0.422
107   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
108   M         0.263   0.068  -0.061   0.454   0.187  -0.068   0.255  -0.045  -0.290
109   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
110   C        -0.847  -0.745  -0.797  -0.893  -0.771  -0.834  -1.043  -0.924  -0.919
111   D         0.963   0.989   1.032   1.025   1.071   1.125   1.012   1.047   1.109
112   A         0.263   0.194  -0.049   0.155   0.079  -0.264   0.255   0.152  -0.270
113   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
114   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
115   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
116   A        -0.404  -0.407  -0.749  -0.462  -0.464  -0.953  -0.394  -0.399  -0.850
117   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
118   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
119   I         0.963   0.989   1.032   1.018   1.047   1.120   1.012   1.047   1.109
120   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
121   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
122   F         0.963   0.989   1.032   1.077   1.118   1.171   1.012   1.047   1.109
123   C         0.963   0.989   1.032   1.200   1.236   1.280   1.012   1.047   1.109
124   H         0.963   0.989   1.032   1.174   1.210   1.257   1.012   1.047   1.109
125   L         0.263   0.378  -0.034   0.293   0.443  -0.140   0.255   0.416  -0.244
126   S         0.963   0.989   1.032   0.939   0.988   1.050   1.012   1.047   1.109
127   V        -0.710  -0.756  -0.797  -0.674  -0.769  -0.810  -0.827  -0.892  -0.917
128   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
129   Q         0.963   0.989   1.032   1.116   1.153   1.206   1.012   1.047   1.109
130   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
131   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
132   I        -0.325  -0.250  -0.135  -0.541  -0.427  -0.235  -0.719  -0.590  -0.424
133   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
134   V         0.263   0.068  -0.061   0.331   0.044  -0.211   0.255  -0.045  -0.290
135   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
136   I         0.963   0.989   1.032   1.018   1.047   1.120   1.012   1.047   1.109
137   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
138   N        -1.613  -1.722  -1.683  -1.310  -1.521  -1.541  -1.367  -1.464  -1.361
139   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
140   I         0.963   0.989   1.032   1.018   1.047   1.120   1.012   1.047   1.109
141   T        -1.032  -1.013  -1.263  -0.769  -0.761  -1.124  -0.935  -0.907  -1.161
142   K        -1.613  -1.743  -1.685  -1.350  -1.561  -1.444  -1.367  -1.482  -1.363
143   L        -2.257  -2.091  -2.000  -2.155  -1.909  -1.822  -1.800  -1.638  -1.472
144   D         0.963   0.989   1.032   1.025   1.071   1.125   1.012   1.047   1.109
145   S        -0.710  -0.683  -0.781  -0.705  -0.632  -0.803  -0.827  -0.763  -0.895
146   I        -0.082  -0.128  -0.133  -0.116  -0.207  -0.232  -0.286  -0.372  -0.420
147   I         0.963   0.989   1.032   1.018   1.047   1.120   1.012   1.047   1.109
148   T         0.963   0.989   1.032   0.997   1.032   1.101   1.012   1.047   1.109
149   S         0.263   0.274  -0.042   0.302   0.331  -0.196   0.255   0.270  -0.257
150   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
151   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
152   C         0.963   0.989   1.032   1.200   1.236   1.280   1.012   1.047   1.109
153   H         0.963   0.989   1.032   1.174   1.210   1.257   1.012   1.047   1.109
154   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
155   F         0.963   0.989   1.032   1.077   1.118   1.171   1.012   1.047   1.109
156   T        -0.325  -0.243  -0.133  -0.709  -0.594  -0.394  -0.719  -0.579  -0.420
157   F        -0.082   0.054  -0.100  -0.071   0.134  -0.124  -0.286  -0.068  -0.360
158   M         0.263   0.068  -0.061   0.467   0.208  -0.031   0.255  -0.045  -0.290
159   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
160   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
161   A        -0.404  -0.656  -0.776  -0.492  -0.860  -1.074  -0.394  -0.726  -0.886
162   S        -0.404  -0.382  -0.743  -0.297  -0.256  -0.843  -0.394  -0.368  -0.843
163   V         0.263   0.068  -0.061   0.368   0.104  -0.103   0.255  -0.045  -0.290
164   K        -1.048  -0.907  -0.820  -1.173  -0.950  -0.818  -1.259  -1.068  -0.944
165   A        -0.847  -0.754  -0.798  -1.159  -1.013  -1.012  -1.043  -0.938  -0.919
166   V        -0.266  -0.281  -0.146  -0.435  -0.483  -0.252  -0.610  -0.647  -0.444
167   L        -0.266  -0.281  -0.146  -0.490  -0.524  -0.292  -0.610  -0.647  -0.444
168   A        -0.266  -0.275  -0.147  -0.752  -0.792  -0.549  -0.610  -0.637  -0.445
169   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
170   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
171   M        -0.082  -0.112  -0.124  -0.053  -0.114  -0.199  -0.286  -0.345  -0.404
172   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
173   R        -0.266  -0.174  -0.132  -0.456  -0.291  -0.257  -0.610  -0.454  -0.418
174   R         0.263   0.068  -0.061   0.406   0.157  -0.043   0.255  -0.045  -0.290
175   A        -1.814  -1.838  -1.684  -1.774  -1.775  -1.601  -1.584  -1.577  -1.363
176   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
177   V        -0.710  -0.865  -0.805  -0.719  -0.985  -0.915  -0.827  -1.007  -0.926
178   S        -0.082  -0.075  -0.123  -0.227  -0.216  -0.373  -0.286  -0.281  -0.402
179   Y        -1.291  -1.282  -1.279  -1.140  -1.130  -1.118  -1.259  -1.223  -1.178
180   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
181   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
182   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
183   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
184   S         0.963   0.989   1.032   0.939   0.988   1.050   1.012   1.047   1.109
185   M         0.963   0.989   1.032   1.071   1.112   1.166   1.012   1.047   1.109
186   H         0.963   0.989   1.032   1.174   1.210   1.257   1.012   1.047   1.109
187   L        -0.847  -0.898  -0.798  -0.900  -0.917  -0.792  -1.043  -1.054  -0.917
188   Y        -0.266  -0.134  -0.116  -0.351  -0.114  -0.133  -0.610  -0.383  -0.390
189   A        -0.266  -0.244  -0.144  -0.630  -0.594  -0.406  -0.610  -0.579  -0.441
190   P        -1.814  -1.709  -1.685  -1.586  -1.495  -1.414  -1.584  -1.473  -1.363
191   G         0.263   0.068  -0.061   0.191  -0.055  -0.218   0.255  -0.045  -0.290
192   F         0.963   0.989   1.032   1.077   1.118   1.171   1.012   1.047   1.109
193   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
194   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
195   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
196   N         0.963   0.989   1.032   1.102   1.143   1.194   1.012   1.047   1.109
197   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
198   I         0.963   0.989   1.032   1.018   1.047   1.120   1.012   1.047   1.109
199   V         0.963   0.989   1.032   0.968   1.002   1.076   1.012   1.047   1.109
200   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
201   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
202   Q         0.963   0.989   1.032   1.116   1.153   1.206   1.012   1.047   1.109
203   V         0.263   0.068  -0.061   0.368   0.104  -0.103   0.255  -0.045  -0.290
204   P         0.263   0.194  -0.049   0.444   0.347  -0.095   0.255   0.152  -0.270
205   L        -0.266  -0.232  -0.144  -0.517  -0.467  -0.323  -0.610  -0.559  -0.439
206   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
207   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
208   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
209   L         0.263   0.068  -0.061   0.305   0.049  -0.154   0.255  -0.045  -0.290
210   A         0.263   0.068  -0.061   0.123  -0.152  -0.376   0.255  -0.045  -0.290
211   F         0.963   0.989   1.032   1.077   1.118   1.171   1.012   1.047   1.109
212   A         0.263   0.351  -0.037   0.147   0.267  -0.266   0.255   0.379  -0.249
213   H         0.263   0.068  -0.061   0.586   0.332   0.099   0.255  -0.045  -0.290
214   Q        -0.266  -0.125  -0.111  -0.409  -0.175  -0.166  -0.610  -0.368  -0.380
215   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
216   K        -1.291  -1.311  -1.299  -1.281  -1.347  -1.288  -1.259  -1.284  -1.198
217   N        -1.491  -1.417  -1.311  -1.514  -1.472  -1.250  -1.476  -1.389  -1.210
218   E        -1.613  -1.743  -1.685  -1.390  -1.605  -1.489  -1.367  -1.482  -1.363
219   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   D        -1.491  -1.533  -1.314  -1.589  -1.622  -1.319  -1.476  -1.478  -1.213
221   A        -1.291  -1.404  -1.300  -1.364  -1.499  -1.304  -1.259  -1.356  -1.199
222   C        -1.291  -1.378  -1.303  -1.110  -1.310  -1.224  -1.259  -1.342  -1.202
223   S        -0.325  -0.273  -0.145  -0.578  -0.485  -0.282  -0.719  -0.633  -0.442
224   F         0.263   0.194  -0.049   0.476   0.395   0.003   0.255   0.152  -0.270
225   T        -1.814  -1.661  -1.665  -1.812  -1.607  -1.536  -1.584  -1.408  -1.346
226   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
227   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
228   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
229   D         0.963   0.989   1.032   1.025   1.071   1.125   1.012   1.047   1.109
230   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
231   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
232   S         0.963   0.989   1.032   0.939   0.988   1.050   1.012   1.047   1.109
233   N         0.963   0.989   1.032   1.102   1.143   1.194   1.012   1.047   1.109
234   Q         0.963   0.989   1.032   1.116   1.153   1.206   1.012   1.047   1.109
235   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
236   Q         0.963   0.989   1.032   1.116   1.153   1.206   1.012   1.047   1.109
237   V        -0.404  -0.588  -0.764  -0.264  -0.558  -0.852  -0.394  -0.641  -0.871
238   F         0.963   0.989   1.032   1.077   1.118   1.171   1.012   1.047   1.109
239   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
240   S        -0.266  -0.270  -0.147  -0.598  -0.633  -0.440  -0.610  -0.627  -0.445
241   F        -0.266  -0.192  -0.132  -0.351  -0.220  -0.164  -0.610  -0.485  -0.418
242   N         0.963   0.989   1.032   1.102   1.143   1.194   1.012   1.047   1.109
243   M         0.963   0.989   1.032   1.071   1.112   1.166   1.012   1.047   1.109
244   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
245   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
246   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
247   W         0.963   0.989   1.032   1.234   1.269   1.310   1.012   1.047   1.109
248   N        -0.710  -0.817  -0.796  -0.586  -0.759  -0.798  -0.827  -0.940  -0.915
249   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
250   P         0.963   0.989   1.032   1.080   1.113   1.174   1.012   1.047   1.109
251   V        -0.969  -0.908  -0.826  -1.079  -0.998  -0.883  -1.151  -1.061  -0.950
252   V        -0.847  -0.875  -0.801  -0.938  -0.975  -0.847  -1.043  -1.050  -0.923
253   F         0.963   0.989   1.032   1.077   1.118   1.171   1.012   1.047   1.109
254   C        -0.847  -0.808  -0.790  -1.016  -0.972  -0.930  -1.043  -0.948  -0.906
255   C         0.963   0.989   1.032   1.200   1.236   1.280   1.012   1.047   1.109
256   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
257   N         0.963   0.989   1.032   1.102   1.143   1.194   1.012   1.047   1.109
258   N         0.963   0.989   1.032   1.102   1.143   1.194   1.012   1.047   1.109
259   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
260   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
261   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
262   M         0.963   0.989   1.032   1.071   1.112   1.166   1.012   1.047   1.109
263   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
264   T         0.963   0.989   1.032   0.997   1.032   1.101   1.012   1.047   1.109
265   A        -0.325  -0.263  -0.140  -0.753  -0.613  -0.417  -0.719  -0.614  -0.433
266   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
267   S        -0.710  -0.753  -0.785  -0.921  -0.962  -1.010  -0.827  -0.852  -0.900
268   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
269   S         0.963   0.989   1.032   0.939   0.988   1.050   1.012   1.047   1.109
270   S         0.963   0.989   1.032   0.939   0.988   1.050   1.012   1.047   1.109
271   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
272   M        -0.082  -0.112  -0.124  -0.053  -0.114  -0.199  -0.286  -0.345  -0.404
273   T         0.963   0.989   1.032   0.997   1.032   1.101   1.012   1.047   1.109
274   E        -0.404  -0.477  -0.755  -0.256  -0.352  -0.729  -0.394  -0.485  -0.859
275   Y         0.263   0.068  -0.061   0.404   0.154  -0.057   0.255  -0.045  -0.290
276   F        -0.266  -0.125  -0.111  -0.380  -0.143  -0.142  -0.610  -0.368  -0.380
277   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
278   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
279   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
280   Q         0.963   0.989   1.032   1.116   1.153   1.206   1.012   1.047   1.109
281   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
282   I         0.963   0.989   1.032   1.018   1.047   1.120   1.012   1.047   1.109
283   P         0.963   0.989   1.032   1.080   1.113   1.174   1.012   1.047   1.109
284   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
285   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
286   K         0.263   0.068  -0.061   0.321   0.063  -0.176   0.255  -0.045  -0.290
287   V         0.263   0.351  -0.037   0.368   0.474  -0.063   0.255   0.379  -0.249
288   N         0.963   0.989   1.032   1.102   1.143   1.194   1.012   1.047   1.109
289   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
290   M         0.963   0.989   1.032   1.071   1.112   1.166   1.012   1.047   1.109
291   D         0.963   0.989   1.032   1.025   1.071   1.125   1.012   1.047   1.109
292   I        -0.266  -0.278  -0.147  -0.417  -0.474  -0.255  -0.610  -0.642  -0.445
293   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
294   A         0.263   0.274  -0.042   0.147   0.174  -0.274   0.255   0.270  -0.257
295   V        -0.404  -0.230  -0.729  -0.195   0.013  -0.631  -0.394  -0.166  -0.825
296   Y        -0.404  -0.656  -0.776  -0.227  -0.591  -0.827  -0.394  -0.726  -0.886
297   Q         0.263   0.194  -0.049   0.480   0.387  -0.065   0.255   0.152  -0.270
298   A         0.263   0.274  -0.042   0.123   0.147  -0.340   0.255   0.270  -0.257
299   S        -0.404  -0.477  -0.755  -0.302  -0.390  -0.877  -0.394  -0.485  -0.859
300   K         0.263   0.194  -0.049   0.301   0.219  -0.213   0.255   0.152  -0.270
301   F         0.263   0.194  -0.049   0.473   0.393  -0.005   0.255   0.152  -0.270
302   A         0.263   0.194  -0.049   0.123   0.038  -0.354   0.255   0.152  -0.270
303   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
304   D        -1.291  -1.422  -1.299  -1.182  -1.362  -1.203  -1.259  -1.366  -1.198
305   W         0.263   0.068  -0.061   0.629   0.362   0.098   0.255  -0.045  -0.290
306   C        -0.847  -0.685  -0.777  -0.830  -0.597  -0.753  -1.043  -0.810  -0.891
307   L        -1.935  -1.858  -1.686  -1.900  -1.766  -1.516  -1.692  -1.590  -1.364
308   S        -1.613  -1.743  -1.685  -1.311  -1.511  -1.382  -1.367  -1.482  -1.363
309   G        -0.404  -0.656  -0.776  -0.394  -0.721  -0.861  -0.394  -0.726  -0.886
310   K        -0.847  -0.921  -0.799  -0.870  -0.941  -0.792  -1.043  -1.088  -0.920
311   G         0.263   0.068  -0.061   0.194  -0.052  -0.212   0.255  -0.045  -0.290
312   P         0.963   0.989   1.032   1.080   1.113   1.174   1.012   1.047   1.109
313   L         0.263   0.378  -0.034   0.305   0.449  -0.110   0.255   0.416  -0.244
314   V         0.263   0.068  -0.061   0.352   0.079  -0.151   0.255  -0.045  -0.290
315   L        -0.082  -0.178  -0.134  -0.160  -0.315  -0.249  -0.286  -0.461  -0.422
316   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
317   Y        -0.082  -0.178  -0.134  -0.071  -0.232  -0.181  -0.286  -0.461  -0.422
318   E        -0.082  -0.206  -0.140  -0.182  -0.419  -0.309  -0.286  -0.512  -0.432
319   T         0.963   0.989   1.032   0.997   1.032   1.101   1.012   1.047   1.109
320   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
321   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
322   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
323   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
324   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
325   H         0.963   0.989   1.032   1.174   1.210   1.257   1.012   1.047   1.109
326   S         0.963   0.989   1.032   0.939   0.988   1.050   1.012   1.047   1.109
327   M         0.963   0.989   1.032   1.071   1.112   1.166   1.012   1.047   1.109
328   S         0.963   0.989   1.032   0.939   0.988   1.050   1.012   1.047   1.109
329   D         0.963   0.989   1.032   1.025   1.071   1.125   1.012   1.047   1.109
330   P         0.963   0.989   1.032   1.080   1.113   1.174   1.012   1.047   1.109
331   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
332   T         0.963   0.989   1.032   0.997   1.032   1.101   1.012   1.047   1.109
333   T         0.963   0.989   1.032   0.997   1.032   1.101   1.012   1.047   1.109
334   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
335   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
336   T         0.263   0.068  -0.061   0.386   0.119  -0.113   0.255  -0.045  -0.290
337   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
338   D        -0.266  -0.125  -0.111  -0.477  -0.245  -0.228  -0.610  -0.368  -0.380
339   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
340   I        -0.266  -0.254  -0.145  -0.417  -0.424  -0.248  -0.610  -0.599  -0.441
341   Q         0.963   0.989   1.032   1.116   1.153   1.206   1.012   1.047   1.109
342   H        -1.032  -1.254  -1.289  -0.621  -0.970  -1.098  -0.935  -1.182  -1.187
343   M         0.263   0.068  -0.061   0.463   0.200  -0.042   0.255  -0.045  -0.290
344   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
345   S         0.263   0.068  -0.061   0.302   0.030  -0.235   0.255  -0.045  -0.290
346   K        -1.814  -1.889  -1.695  -1.726  -1.858  -1.545  -1.584  -1.611  -1.371
347   N         0.263   0.068  -0.061   0.497   0.237  -0.008   0.255  -0.045  -0.290
348   D         0.963   0.989   1.032   1.025   1.071   1.125   1.012   1.047   1.109
349   P         0.963   0.989   1.032   1.080   1.113   1.174   1.012   1.047   1.109
350   I         0.963   0.989   1.032   1.018   1.047   1.120   1.012   1.047   1.109
351   A        -0.404  -0.588  -0.764  -0.462  -0.723  -0.978  -0.394  -0.641  -0.871
352   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
353   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
354   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
355   M        -1.370  -1.468  -1.303  -1.433  -1.548  -1.281  -1.367  -1.420  -1.202
356   H        -0.404  -0.230  -0.729  -0.031   0.189  -0.563  -0.394  -0.166  -0.825
357   L        -0.266  -0.281  -0.146  -0.490  -0.524  -0.292  -0.610  -0.647  -0.444
358   I        -0.404  -0.472  -0.754  -0.276  -0.378  -0.757  -0.394  -0.504  -0.858
359   D         0.263   0.407  -0.033   0.317   0.485  -0.095   0.255   0.456  -0.241
360   L        -0.710  -0.748  -0.804  -0.661  -0.714  -0.761  -0.827  -0.911  -0.926
361   G        -1.032  -0.882  -1.246  -0.984  -0.788  -1.250  -0.935  -0.753  -1.142
362   I        -0.710  -0.804  -0.807  -0.631  -0.827  -0.791  -0.827  -0.968  -0.930
363   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
364   T        -0.710  -0.865  -0.805  -0.657  -0.870  -0.803  -0.827  -1.007  -0.926
365   E         0.263   0.068  -0.061   0.279  -0.011  -0.254   0.255  -0.045  -0.290
366   A        -1.370  -1.363  -1.288  -1.402  -1.365  -1.266  -1.367  -1.339  -1.189
367   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
368   V        -1.048  -0.901  -0.818  -1.245  -1.031  -0.893  -1.259  -1.062  -0.941
369   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
370   A        -1.048  -1.018  -0.834  -1.336  -1.223  -0.952  -1.259  -1.206  -0.961
371   Y        -1.032  -1.254  -1.289  -0.800  -1.138  -1.225  -0.935  -1.182  -1.187
372   D         0.263   0.068  -0.061   0.410   0.147  -0.101   0.255  -0.045  -0.290
373   K         0.963   0.989   1.032   0.938   0.986   1.049   1.012   1.047   1.109
374   S        -1.032  -1.154  -1.277  -1.045  -1.235  -1.386  -0.935  -1.082  -1.174
375   A         0.263   0.068  -0.061   0.159  -0.092  -0.271   0.255  -0.045  -0.290
376   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
377   K        -0.710  -0.889  -0.808  -0.844  -1.161  -1.084  -0.827  -1.042  -0.930
378   Y        -0.082  -0.178  -0.134  -0.073  -0.235  -0.185  -0.286  -0.461  -0.422
379   V         0.963   0.989   1.032   0.968   1.002   1.076   1.012   1.047   1.109
380   D         0.263   0.194  -0.049   0.436   0.366  -0.005   0.255   0.152  -0.270
381   E         0.263   0.274  -0.042   0.304   0.317  -0.145   0.255   0.270  -0.257
382   Q        -0.266  -0.281  -0.146  -0.358  -0.441  -0.227  -0.610  -0.647  -0.444
383   V         0.963   0.989   1.032   0.968   1.002   1.076   1.012   1.047   1.109
384   E        -0.847  -0.898  -0.798  -1.158  -1.191  -1.008  -1.043  -1.054  -0.917
385   L        -1.291  -1.341  -1.296  -1.391  -1.488  -1.406  -1.259  -1.304  -1.196
386   A         0.963   0.989   1.032   0.759   0.803   0.891   1.012   1.047   1.109
387   D        -0.266  -0.125  -0.111  -0.477  -0.245  -0.228  -0.610  -0.368  -0.380
388   A        -1.032  -1.094  -1.266  -1.057  -1.167  -1.395  -0.935  -1.014  -1.164
389   A        -1.491  -1.467  -1.306  -1.601  -1.522  -1.306  -1.476  -1.419  -1.206
390   P        -0.266  -0.145  -0.121  -0.470  -0.231  -0.259  -0.610  -0.402  -0.398
391   P        -0.710  -0.820  -0.795  -0.649  -0.794  -0.831  -0.827  -0.944  -0.913
392   P         0.963   0.989   1.032   1.080   1.113   1.174   1.012   1.047   1.109
393   E         0.263   0.068  -0.061   0.317   0.056  -0.142   0.255  -0.045  -0.290
394   A         0.263   0.068  -0.061   0.168  -0.074  -0.244   0.255  -0.045  -0.290
395   K        -1.032  -1.254  -1.289  -0.812  -1.120  -1.170  -0.935  -1.182  -1.187
396   L        -1.814  -1.874  -1.688  -1.702  -1.791  -1.559  -1.584  -1.597  -1.366
397   S        -1.814  -1.889  -1.695  -1.698  -1.793  -1.515  -1.584  -1.611  -1.371
398   I        -0.404  -0.588  -0.764  -0.194  -0.469  -0.763  -0.394  -0.641  -0.871
399   L         0.963   0.989   1.032   0.905   0.946   1.020   1.012   1.047   1.109
400   F         0.963   0.989   1.032   1.077   1.118   1.171   1.012   1.047   1.109
401   E         0.263   0.068  -0.061   0.305   0.035  -0.178   0.255  -0.045  -0.290
402   D         0.963   0.989   1.032   1.025   1.071   1.125   1.012   1.047   1.109
403   V        -0.082  -0.112  -0.124  -0.116  -0.180  -0.216  -0.286  -0.345  -0.404
404   Y         0.963   0.989   1.032   0.996   1.035   1.100   1.012   1.047   1.109
405   V         0.963   0.989   1.032   0.968   1.002   1.076   1.012   1.047   1.109
406   K        -0.847  -0.935  -0.803  -0.924  -1.060  -0.886  -1.043  -1.108  -0.925
407   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
408   T        -0.266  -0.155  -0.124  -0.451  -0.251  -0.237  -0.610  -0.420  -0.404
409   E         0.963   0.989   1.032   0.916   0.947   1.030   1.012   1.047   1.109
410   T        -1.048  -0.916  -0.819  -1.120  -0.902  -0.774  -1.259  -1.076  -0.942
411   P        -1.032  -1.171  -1.282  -0.749  -1.004  -1.224  -0.935  -1.099  -1.180
412   T        -1.814  -1.852  -1.690  -1.676  -1.736  -1.500  -1.584  -1.588  -1.367
413   L        -0.710  -0.889  -0.808  -0.779  -1.078  -0.965  -0.827  -1.042  -0.930
414   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
415   G         0.963   0.989   1.032   0.779   0.815   0.909   1.012   1.047   1.109
416   R         0.963   0.989   1.032   0.993   1.029   1.097   1.012   1.047   1.109
417   I        -1.032  -1.176  -1.278  -0.756  -0.975  -1.148  -0.935  -1.104  -1.176
418   P        -0.847  -0.756  -0.795  -0.851  -0.749  -0.741  -1.043  -0.938  -0.917
419   E        -1.370  -1.427  -1.298  -1.407  -1.472  -1.283  -1.367  -1.385  -1.197
420   D        -0.266  -0.281  -0.146  -0.439  -0.503  -0.285  -0.610  -0.647  -0.444
421   T        -1.613  -1.743  -1.685  -1.362  -1.581  -1.526  -1.367  -1.482  -1.363
422   W        -1.032  -1.254  -1.289  -0.504  -0.818  -0.939  -0.935  -1.182  -1.187
423   D        -1.291  -1.357  -1.301  -1.111  -1.212  -1.104  -1.259  -1.324  -1.200
424   F         0.263   0.068  -0.061   0.473   0.215  -0.026   0.255  -0.045  -0.290
425   K        -1.032  -0.742  -1.233  -0.900  -0.502  -1.256  -0.935  -0.590  -1.129
426   K         0.033  -0.015  -0.119   0.047  -0.024  -0.190  -0.096  -0.181  -0.395
427   Q        -1.512  -1.404  -1.316  -1.544  -1.393  -1.255  -1.480  -1.343  -1.214
428   G        -1.512  -1.390  -1.320  -1.604  -1.397  -1.357  -1.480  -1.327  -1.218
429   F         0.963   0.989   1.032   1.076   1.114   1.171   1.012   1.047   1.109
430   A        -0.997  -0.947  -0.828  -1.384  -1.293  -1.088  -1.203  -1.124  -0.953
431   S        -1.512  -1.390  -1.320  -1.427  -1.234  -1.190  -1.480  -1.327  -1.218
432   R         0.033  -0.015  -0.119   0.081   0.000  -0.220  -0.096  -0.181  -0.395
433   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
434   D        -1.410  -1.485  -1.315  -1.275  -1.347  -1.101  -1.389  -1.432  -1.213
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P16387
Output conservation file - output/P16387
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
