1     M         1.161   1.170   1.236   1.332   1.344   1.431   1.236   1.251   1.347
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    S        -0.674  -0.862  -0.916  -0.585  -0.877  -1.015  -0.642  -0.872  -0.915
13    E        -0.985  -0.869  -0.932  -1.129  -0.940  -0.979  -1.060  -0.931  -0.936
14    E        -0.200  -0.264  -0.430  -0.258  -0.367  -0.612  -0.263  -0.362  -0.599
15    G         1.161   1.170   1.236   1.119   1.125   1.236   1.236   1.251   1.347
16    P        -0.097  -0.245  -0.401   0.065  -0.149  -0.400  -0.121  -0.330  -0.559
17    Q        -1.393  -1.428  -1.326  -1.167  -1.222  -1.083  -1.268  -1.296  -1.133
18    V        -0.097  -0.245  -0.401  -0.001  -0.211  -0.487  -0.121  -0.330  -0.559
19    K        -0.505  -0.542  -0.482  -0.653  -0.701  -0.608  -0.747  -0.783  -0.678
20    I         0.517   0.438   0.273   0.553   0.446   0.176   0.505   0.379   0.068
21    R         0.517   0.445   0.276   0.689   0.589   0.318   0.505   0.389   0.073
22    E        -1.209  -1.325  -1.302  -1.092  -1.266  -1.183  -1.060  -1.183  -1.111
23    A        -0.674  -0.760  -0.893  -0.570  -0.693  -0.883  -0.642  -0.755  -0.890
24    S        -1.505  -1.469  -1.323  -1.587  -1.524  -1.310  -1.373  -1.332  -1.132
25    K        -0.097  -0.069  -0.369   0.036   0.065  -0.348  -0.121  -0.096  -0.514
26    D        -1.209  -1.325  -1.302  -1.176  -1.360  -1.353  -1.060  -1.183  -1.111
27    N        -1.393  -1.474  -1.334  -1.207  -1.325  -1.120  -1.268  -1.328  -1.140
28    V         1.161   1.170   1.236   1.148   1.166   1.263   1.236   1.251   1.347
29    D        -0.200  -0.250  -0.427  -0.204  -0.269  -0.549  -0.263  -0.343  -0.596
30    F         1.161   1.170   1.236   1.321   1.331   1.421   1.236   1.251   1.347
31    I        -0.200  -0.384  -0.447  -0.168  -0.455  -0.596  -0.263  -0.527  -0.623
32    L         1.161   1.170   1.236   1.059   1.070   1.182   1.236   1.251   1.347
33    S        -0.473  -0.519  -0.481  -0.573  -0.628  -0.580  -0.672  -0.726  -0.672
34    N        -0.097  -0.120  -0.387   0.070   0.042  -0.362  -0.121  -0.162  -0.540
35    V        -0.378  -0.499  -0.476  -0.416  -0.616  -0.594  -0.538  -0.713  -0.668
36    D        -0.674  -0.862  -0.916  -0.645  -0.926  -1.046  -0.642  -0.872  -0.915
37    L         0.517   0.438   0.273   0.479   0.372   0.131   0.505   0.379   0.068
38    A        -0.097  -0.239  -0.406  -0.044  -0.234  -0.496  -0.121  -0.322  -0.565
39    M        -1.097  -1.086  -0.962  -1.147  -1.129  -0.904  -1.164  -1.142  -0.969
40    A         1.161   1.170   1.236   1.081   1.100   1.202   1.236   1.251   1.347
41    N         1.161   1.170   1.236   1.186   1.198   1.298   1.236   1.251   1.347
42    S         1.161   1.170   1.236   1.138   1.156   1.254   1.236   1.251   1.347
43    L         0.200   0.272   0.208   0.084   0.184   0.103  -0.016   0.103  -0.053
44    R         1.161   1.170   1.236   1.259   1.266   1.365   1.236   1.251   1.347
45    R         1.161   1.170   1.236   1.259   1.266   1.365   1.236   1.251   1.347
46    V         0.200   0.272   0.208   0.131   0.248   0.122  -0.016   0.103  -0.053
47    M        -0.097  -0.120  -0.379   0.198   0.159  -0.264  -0.121  -0.162  -0.528
48    I        -0.024   0.022   0.134  -0.382  -0.311  -0.118  -0.434  -0.357  -0.193
49    A         0.517   0.581   0.297   0.510   0.597   0.200   0.505   0.598   0.112
50    E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
51    I         0.200   0.272   0.208   0.105   0.222   0.093  -0.016   0.103  -0.053
52    P         1.161   1.170   1.236   1.190   1.194   1.301   1.236   1.251   1.347
53    T         1.161   1.170   1.236   1.192   1.205   1.303   1.236   1.251   1.347
54    L        -0.097  -0.239  -0.399  -0.083  -0.285  -0.528  -0.121  -0.322  -0.556
55    A         1.161   1.170   1.236   1.081   1.100   1.202   1.236   1.251   1.347
56    I         1.161   1.170   1.236   1.136   1.150   1.252   1.236   1.251   1.347
57    D         1.161   1.170   1.236   1.066   1.090   1.189   1.236   1.251   1.347
58    S         0.030   0.128   0.183  -0.284  -0.113  -0.029  -0.329  -0.156  -0.100
59    V         1.161   1.170   1.236   1.148   1.166   1.263   1.236   1.251   1.347
60    E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
61    V         0.200   0.333   0.241   0.105   0.316   0.153  -0.016   0.207   0.009
62    E        -0.674  -0.761  -0.893  -0.662  -0.791  -0.999  -0.642  -0.756  -0.890
63    T        -0.505  -0.537  -0.481  -0.633  -0.674  -0.590  -0.747  -0.778  -0.678
64    N         1.161   1.170   1.236   1.186   1.198   1.298   1.236   1.251   1.347
65    T         0.517   0.445   0.276   0.622   0.528   0.260   0.505   0.389   0.073
66    T         0.030   0.128   0.183  -0.177  -0.001   0.069  -0.329  -0.156  -0.100
67    V         1.161   1.170   1.236   1.148   1.166   1.263   1.236   1.251   1.347
68    L         0.517   0.438   0.280   0.508   0.409   0.212   0.505   0.379   0.080
69    A         0.517   0.438   0.280   0.518   0.421   0.188   0.505   0.379   0.080
70    D         1.161   1.170   1.236   1.066   1.090   1.189   1.236   1.251   1.347
71    E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
72    F         1.161   1.170   1.236   1.328   1.339   1.427   1.236   1.251   1.347
73    I         0.030   0.061   0.134  -0.254  -0.204  -0.105  -0.329  -0.283  -0.193
74    A         0.030   0.049   0.134  -0.256  -0.221  -0.094  -0.329  -0.305  -0.192
75    H         1.161   1.170   1.236   1.336   1.346   1.435   1.236   1.251   1.347
76    R         1.161   1.170   1.236   1.259   1.266   1.365   1.236   1.251   1.347
77    L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
78    G         1.161   1.170   1.236   1.124   1.135   1.241   1.236   1.251   1.347
79    L         0.517   0.438   0.280   0.508   0.409   0.212   0.505   0.379   0.080
80    I         1.161   1.170   1.236   1.136   1.150   1.252   1.236   1.251   1.347
81    P         1.161   1.170   1.236   1.190   1.194   1.301   1.236   1.251   1.347
82    L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
83    Q        -1.097  -1.064  -0.971  -1.137  -1.126  -0.976  -1.164  -1.136  -0.977
84    S         0.517   0.445   0.276   0.559   0.468   0.193   0.505   0.389   0.073
85    M        -1.689  -1.612  -1.604  -1.577  -1.488  -1.429  -1.373  -1.309  -1.228
86    D        -0.505  -0.541  -0.481  -0.730  -0.764  -0.649  -0.747  -0.782  -0.677
87    I         0.517   0.438   0.273   0.567   0.466   0.210   0.505   0.379   0.068
88    E        -0.505  -0.528  -0.469  -0.790  -0.797  -0.687  -0.747  -0.761  -0.661
89    Q        -0.913  -0.977  -0.940  -0.830  -0.935  -0.934  -0.955  -1.015  -0.944
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    L         0.517   0.581   0.297   0.481   0.557   0.176   0.505   0.598   0.112
96    E        -1.209  -1.136  -1.273  -1.195  -1.109  -1.307  -1.060  -0.987  -1.084
97    Y         1.161   1.170   1.236   1.269   1.281   1.374   1.236   1.251   1.347
98    S        -0.097  -0.117  -0.373   0.043   0.013  -0.336  -0.121  -0.158  -0.520
99    R         1.161   1.170   1.236   1.259   1.266   1.365   1.236   1.251   1.347
100   D         0.517   0.438   0.280   0.503   0.412   0.174   0.505   0.379   0.080
101   C         1.161   1.170   1.236   1.314   1.324   1.415   1.236   1.251   1.347
102   F        -1.505  -1.450  -1.330  -1.434  -1.383  -1.182  -1.373  -1.314  -1.136
103   C         1.161   1.170   1.236   1.314   1.324   1.415   1.236   1.251   1.347
104   E         0.030   0.128   0.183  -0.328  -0.132  -0.067  -0.329  -0.156  -0.100
105   D        -1.097  -1.064  -0.971  -1.261  -1.227  -1.038  -1.164  -1.136  -0.978
106   H         0.030   0.128   0.183   0.013   0.173   0.241  -0.329  -0.156  -0.100
107   C         1.161   1.170   1.236   1.314   1.324   1.415   1.236   1.251   1.347
108   D        -1.209  -1.235  -1.294  -1.181  -1.231  -1.349  -1.060  -1.093  -1.104
109   K        -0.674  -0.640  -0.867  -0.472  -0.425  -0.731  -0.642  -0.610  -0.861
110   C         1.161   1.170   1.236   1.314   1.324   1.415   1.236   1.251   1.347
111   S         1.161   1.170   1.236   1.138   1.156   1.254   1.236   1.251   1.347
112   V         1.161   1.170   1.236   1.148   1.166   1.263   1.236   1.251   1.347
113   V        -1.097  -1.054  -0.965  -1.255  -1.204  -1.051  -1.164  -1.123  -0.972
114   L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
115   T        -2.097  -2.076  -1.885  -1.792  -1.745  -1.499  -1.581  -1.556  -1.328
116   L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
117   Q        -1.801  -1.771  -1.619  -1.549  -1.522  -1.325  -1.477  -1.443  -1.240
118   A         1.161   1.170   1.236   1.081   1.100   1.202   1.236   1.251   1.347
119   F        -1.689  -1.530  -1.587  -1.486  -1.271  -1.349  -1.373  -1.231  -1.215
120   G         0.030   0.128   0.183  -0.057   0.128   0.181  -0.329  -0.156  -0.100
121   E        -0.985  -0.869  -0.932  -1.153  -0.949  -1.039  -1.060  -0.931  -0.936
122   S        -0.689  -0.607  -0.500  -0.923  -0.790  -0.622  -0.955  -0.848  -0.698
123   E         0.030   0.021   0.125  -0.341  -0.366  -0.193  -0.329  -0.360  -0.210
124   S        -0.378  -0.499  -0.476  -0.460  -0.665  -0.644  -0.538  -0.713  -0.668
125   T         0.517   0.445   0.276   0.621   0.527   0.259   0.505   0.389   0.073
126   T         0.030   0.128   0.183  -0.007   0.174   0.225  -0.329  -0.156  -0.100
127   N        -1.209  -1.325  -1.302  -1.045  -1.246  -1.246  -1.060  -1.183  -1.111
128   V         0.200   0.122   0.156   0.113  -0.027  -0.002  -0.016  -0.168  -0.151
129   Y         0.517   0.445   0.276   0.724   0.633   0.386   0.505   0.389   0.073
130   S         0.030   0.061   0.132  -0.256  -0.198  -0.099  -0.329  -0.282  -0.197
131   K        -0.689  -0.607  -0.500  -0.852  -0.700  -0.550  -0.955  -0.848  -0.698
132   D         1.161   1.170   1.236   1.066   1.090   1.189   1.236   1.251   1.347
133   L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
134   V        -1.393  -1.300  -1.291  -1.301  -1.155  -1.154  -1.268  -1.176  -1.104
135   I        -1.097  -1.107  -0.973  -1.217  -1.225  -1.014  -1.164  -1.167  -0.979
136   V        -1.689  -1.670  -1.609  -1.383  -1.365  -1.251  -1.373  -1.355  -1.232
137   S        -0.674  -0.755  -0.899  -0.501  -0.625  -0.825  -0.642  -0.749  -0.897
138   N        -0.913  -0.928  -0.925  -0.869  -0.906  -0.881  -0.955  -0.978  -0.931
139   L        -0.463  -0.603  -0.511  -0.557  -0.785  -0.614  -0.634  -0.838  -0.712
140   M        -1.507  -1.517  -1.344  -1.411  -1.475  -1.237  -1.361  -1.367  -1.148
141   G        -0.200  -0.379  -0.447  -0.132  -0.394  -0.488  -0.263  -0.519  -0.623
142   R        -0.985  -1.039  -0.952  -0.949  -1.014  -0.868  -1.060  -1.097  -0.957
143   N        -1.393  -1.474  -1.334  -1.386  -1.518  -1.329  -1.268  -1.328  -1.140
144   I         0.030   0.128   0.183  -0.285  -0.115  -0.030  -0.329  -0.156  -0.100
145   G         1.161   1.170   1.236   1.124   1.135   1.241   1.236   1.251   1.347
146   H        -0.913  -0.973  -0.944  -0.789  -0.868  -0.889  -0.955  -1.010  -0.948
147   P         1.161   1.170   1.236   1.190   1.194   1.301   1.236   1.251   1.347
148   I         0.200   0.272   0.208   0.105   0.222   0.093  -0.016   0.103  -0.053
149   I        -0.674  -0.760  -0.893  -0.553  -0.685  -0.911  -0.642  -0.755  -0.890
150   Q        -1.393  -1.474  -1.334  -1.209  -1.343  -1.159  -1.268  -1.328  -1.140
151   D         1.161   1.170   1.236   1.066   1.090   1.189   1.236   1.251   1.347
152   K        -0.913  -0.729  -0.891  -0.851  -0.578  -0.802  -0.955  -0.729  -0.888
153   E        -1.209  -1.239  -1.295  -1.116  -1.187  -1.214  -1.060  -1.098  -1.105
154   G        -1.393  -1.408  -1.310  -1.410  -1.431  -1.273  -1.268  -1.273  -1.121
155   N        -1.097  -1.120  -0.973  -1.100  -1.126  -0.895  -1.164  -1.180  -0.979
156   G         1.161   1.170   1.236   1.124   1.135   1.241   1.236   1.251   1.347
157   V        -0.505  -0.496  -0.462  -0.623  -0.583  -0.529  -0.747  -0.709  -0.647
158   L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
159   I         1.161   1.170   1.236   1.136   1.150   1.252   1.236   1.251   1.347
160   C         0.517   0.445   0.276   0.732   0.629   0.336   0.505   0.389   0.073
161   K         1.161   1.170   1.236   1.142   1.160   1.257   1.236   1.251   1.347
162   L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
163   R         1.161   1.170   1.236   1.259   1.266   1.365   1.236   1.251   1.347
164   K         0.517   0.445   0.276   0.600   0.518   0.285   0.505   0.389   0.073
165   G        -0.913  -0.977  -0.940  -0.873  -0.973  -0.922  -0.955  -1.015  -0.944
166   Q         1.161   1.170   1.236   1.277   1.287   1.381   1.236   1.251   1.347
167   E         0.517   0.438   0.273   0.459   0.355   0.113   0.505   0.379   0.068
168   L         0.030   0.021   0.126  -0.285  -0.313  -0.132  -0.329  -0.359  -0.208
169   K        -0.689  -0.666  -0.521  -0.852  -0.816  -0.595  -0.955  -0.927  -0.725
170   L        -0.378  -0.338  -0.444  -0.513  -0.474  -0.608  -0.538  -0.501  -0.624
171   T        -0.913  -1.016  -0.940  -0.828  -0.974  -0.857  -0.955  -1.067  -0.946
172   C         1.161   1.170   1.236   1.314   1.324   1.415   1.236   1.251   1.347
173   V         0.517   0.628   0.300   0.567   0.703   0.256   0.505   0.665   0.117
174   A         1.161   1.170   1.236   1.081   1.100   1.202   1.236   1.251   1.347
175   K         1.161   1.170   1.236   1.142   1.160   1.257   1.236   1.251   1.347
176   K         1.161   1.170   1.236   1.142   1.160   1.257   1.236   1.251   1.347
177   G         1.161   1.170   1.236   1.124   1.135   1.241   1.236   1.251   1.347
178   I         1.161   1.170   1.236   1.136   1.150   1.252   1.236   1.251   1.347
179   A         0.517   0.581   0.297   0.510   0.597   0.200   0.505   0.598   0.112
180   K         1.161   1.170   1.236   1.142   1.160   1.257   1.236   1.251   1.347
181   E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
182   H         1.161   1.170   1.236   1.336   1.346   1.435   1.236   1.251   1.347
183   A         0.517   0.445   0.276   0.510   0.423   0.163   0.505   0.389   0.073
184   K         1.161   1.170   1.236   1.142   1.160   1.257   1.236   1.251   1.347
185   W         1.161   1.170   1.236   1.347   1.356   1.445   1.236   1.251   1.347
186   G        -0.378  -0.330  -0.414  -0.446  -0.347  -0.512  -0.538  -0.453  -0.578
187   P         1.161   1.170   1.236   1.190   1.194   1.301   1.236   1.251   1.347
188   A        -1.209  -1.155  -0.982  -1.304  -1.208  -0.958  -1.268  -1.211  -0.987
189   A        -0.097  -0.120  -0.376  -0.055  -0.086  -0.472  -0.121  -0.162  -0.523
190   A         1.161   1.170   1.236   1.081   1.100   1.202   1.236   1.251   1.347
191   I         0.517   0.438   0.280   0.567   0.466   0.221   0.505   0.379   0.080
192   E        -0.505  -0.496  -0.460  -0.764  -0.712  -0.657  -0.747  -0.709  -0.646
193   F         1.161   1.170   1.236   1.328   1.339   1.427   1.236   1.251   1.347
194   E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
195   Y         1.161   1.170   1.236   1.269   1.281   1.374   1.236   1.251   1.347
196   D         1.161   1.170   1.236   1.066   1.090   1.189   1.236   1.251   1.347
197   P         1.161   1.170   1.236   1.190   1.194   1.301   1.236   1.251   1.347
198   W         0.517   0.445   0.276   0.804   0.711   0.459   0.505   0.389   0.073
199   N         1.161   1.170   1.236   1.186   1.198   1.298   1.236   1.251   1.347
200   K         1.161   1.170   1.236   1.142   1.160   1.257   1.236   1.251   1.347
201   L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
202   K        -0.378  -0.429  -0.451  -0.335  -0.393  -0.416  -0.538  -0.604  -0.636
203   H         1.161   1.170   1.236   1.336   1.346   1.435   1.236   1.251   1.347
204   T         0.517   0.445   0.276   0.609   0.510   0.230   0.505   0.389   0.073
205   D         1.161   1.170   1.236   1.066   1.090   1.189   1.236   1.251   1.347
206   Y         0.517   0.445   0.276   0.687   0.586   0.297   0.505   0.389   0.073
207   W         1.161   1.170   1.236   1.347   1.356   1.445   1.236   1.251   1.347
208   Y         0.517   0.438   0.280   0.725   0.627   0.397   0.505   0.379   0.080
209   E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
210   Q        -1.393  -1.356  -1.303  -1.347  -1.303  -1.247  -1.268  -1.232  -1.115
211   D         0.517   0.438   0.273   0.503   0.412   0.163   0.505   0.379   0.068
212   S        -0.674  -0.560  -0.861  -0.595  -0.446  -0.879  -0.642  -0.517  -0.854
213   A        -1.505  -1.446  -1.324  -1.633  -1.563  -1.367  -1.373  -1.316  -1.133
214   K        -1.097  -1.054  -0.966  -1.340  -1.286  -1.145  -1.164  -1.124  -0.973
215   E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
216   W         1.161   1.170   1.236   1.347   1.356   1.445   1.236   1.251   1.347
217   P         1.161   1.170   1.236   1.190   1.194   1.301   1.236   1.251   1.347
218   Q        -0.985  -1.039  -0.952  -0.987  -1.068  -0.943  -1.060  -1.097  -0.957
219   S         1.161   1.170   1.236   1.138   1.156   1.254   1.236   1.251   1.347
220   K        -0.097  -0.114  -0.382  -0.019  -0.046  -0.485  -0.121  -0.153  -0.532
221   N         0.517   0.445   0.276   0.634   0.544   0.300   0.505   0.389   0.073
222   C         0.030   0.004   0.123  -0.079  -0.168   0.009  -0.329  -0.392  -0.214
223   E         0.030   0.128   0.183  -0.328  -0.132  -0.067  -0.329  -0.156  -0.100
224   Y        -0.378  -0.212  -0.409  -0.151   0.088  -0.199  -0.538  -0.301  -0.571
225   E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
226   D         0.030   0.128   0.183  -0.341  -0.158  -0.080  -0.329  -0.156  -0.100
227   P         0.200   0.272   0.208   0.137   0.246   0.110  -0.016   0.103  -0.053
228   P         1.161   1.170   1.236   1.190   1.194   1.301   1.236   1.251   1.347
229   N        -1.393  -1.474  -1.334  -1.326  -1.422  -1.215  -1.268  -1.328  -1.140
230   E        -0.674  -0.488  -0.856  -0.672  -0.422  -0.959  -0.642  -0.420  -0.848
231   G        -0.985  -0.966  -0.927  -1.160  -1.111  -1.045  -1.060  -1.031  -0.934
232   D        -0.378  -0.226  -0.415  -0.570  -0.346  -0.627  -0.538  -0.337  -0.580
233   P         0.517   0.581   0.297   0.610   0.683   0.273   0.505   0.598   0.112
234   F         1.161   1.170   1.236   1.328   1.339   1.427   1.236   1.251   1.347
235   D         0.517   0.438   0.280   0.503   0.412   0.174   0.505   0.379   0.080
236   Y         0.517   0.438   0.280   0.725   0.627   0.397   0.505   0.379   0.080
237   K        -1.209  -1.323  -1.298  -1.021  -1.198  -1.161  -1.060  -1.182  -1.108
238   A         0.517   0.438   0.280   0.495   0.393   0.132   0.505   0.379   0.080
239   Q        -0.674  -0.716  -0.882  -0.536  -0.617  -0.867  -0.642  -0.706  -0.877
240   A         0.200   0.333   0.241   0.137   0.344   0.174  -0.016   0.207   0.009
241   D        -1.505  -1.507  -1.329  -1.515  -1.475  -1.210  -1.373  -1.358  -1.135
242   T        -0.378  -0.499  -0.476  -0.332  -0.524  -0.493  -0.538  -0.713  -0.668
243   F         0.517   0.578   0.291   0.775   0.848   0.446   0.505   0.593   0.100
244   Y         1.161   1.170   1.236   1.269   1.281   1.374   1.236   1.251   1.347
245   M        -0.913  -0.926  -0.926  -0.694  -0.732  -0.727  -0.955  -0.976  -0.931
246   N         0.030   0.049   0.136  -0.200  -0.169  -0.053  -0.329  -0.305  -0.189
247   V         1.161   1.170   1.236   1.148   1.166   1.263   1.236   1.251   1.347
248   E         1.161   1.170   1.236   1.029   1.040   1.155   1.236   1.251   1.347
249   S        -0.689  -0.659  -0.525  -0.927  -0.876  -0.680  -0.955  -0.918  -0.731
250   V        -0.097  -0.239  -0.406   0.014  -0.181  -0.463  -0.121  -0.322  -0.565
251   G         1.161   1.170   1.236   1.124   1.135   1.241   1.236   1.251   1.347
252   S        -0.913  -0.973  -0.944  -0.917  -0.998  -0.971  -0.955  -1.010  -0.948
253   I         0.030   0.049   0.134  -0.254  -0.229  -0.105  -0.329  -0.305  -0.192
254   P        -0.378  -0.298  -0.438  -0.371  -0.283  -0.486  -0.538  -0.455  -0.617
255   V        -0.913  -0.836  -0.913  -0.855  -0.724  -0.845  -0.955  -0.853  -0.913
256   D        -0.985  -0.972  -0.942  -1.093  -1.053  -0.997  -1.060  -1.041  -0.949
257   Q        -0.505  -0.491  -0.461  -0.685  -0.661  -0.603  -0.747  -0.703  -0.647
258   V         0.200   0.124   0.157   0.113  -0.021   0.000  -0.016  -0.163  -0.149
259   V        -0.378  -0.386  -0.441  -0.384  -0.367  -0.456  -0.538  -0.537  -0.617
260   V        -0.985  -0.972  -0.930  -1.126  -1.103  -1.007  -1.060  -1.041  -0.937
261   R        -0.913  -0.973  -0.939  -0.818  -0.904  -0.885  -0.955  -1.010  -0.943
262   G         0.517   0.578   0.291   0.553   0.629   0.226   0.505   0.593   0.100
263   I        -0.097  -0.245  -0.401   0.020  -0.182  -0.423  -0.121  -0.330  -0.559
264   D        -1.505  -1.509  -1.328  -1.608  -1.566  -1.286  -1.373  -1.360  -1.135
265   T        -0.378  -0.499  -0.476  -0.375  -0.578  -0.556  -0.538  -0.713  -0.668
266   L         0.517   0.445   0.276   0.479   0.380   0.135   0.505   0.389   0.073
267   Q         1.161   1.170   1.236   1.277   1.287   1.381   1.236   1.251   1.347
268   K        -1.689  -1.667  -1.608  -1.600  -1.577  -1.524  -1.373  -1.353  -1.231
269   K         1.161   1.170   1.236   1.142   1.160   1.257   1.236   1.251   1.347
270   V         0.030   0.128   0.183  -0.278  -0.108  -0.024  -0.329  -0.156  -0.100
271   A         1.161   1.170   1.236   1.081   1.100   1.202   1.236   1.251   1.347
272   S        -1.801  -1.770  -1.621  -1.872  -1.831  -1.624  -1.477  -1.442  -1.241
273   I        -0.378  -0.499  -0.476  -0.463  -0.678  -0.646  -0.538  -0.713  -0.668
274   L        -1.505  -1.433  -1.329  -1.569  -1.465  -1.270  -1.373  -1.303  -1.136
275   L        -1.801  -1.768  -1.624  -1.543  -1.466  -1.259  -1.477  -1.440  -1.243
276   A        -1.393  -1.382  -1.311  -1.550  -1.523  -1.412  -1.268  -1.245  -1.119
277   L         1.161   1.170   1.236   1.050   1.058   1.173   1.236   1.251   1.347
278   T        -1.393  -1.424  -1.307  -1.353  -1.415  -1.247  -1.268  -1.291  -1.118
279   Q        -1.097  -1.090  -0.960  -1.234  -1.253  -1.043  -1.164  -1.149  -0.966
280   M        -1.393  -1.428  -1.325  -1.283  -1.364  -1.239  -1.268  -1.296  -1.133
281   D        -0.097  -0.120  -0.376  -0.043  -0.063  -0.429  -0.121  -0.162  -0.523
282   Q        -1.393  -1.372  -1.323  -1.277  -1.287  -1.210  -1.268  -1.252  -1.131
283   D        -1.209  -1.292  -1.292  -1.212  -1.355  -1.362  -1.060  -1.154  -1.102
284   K        -1.689  -1.736  -1.629  -1.586  -1.678  -1.541  -1.373  -1.411  -1.247
285   V        -1.393  -1.430  -1.323  -1.395  -1.466  -1.307  -1.268  -1.297  -1.131
286   N        -1.209  -1.325  -1.301  -1.079  -1.284  -1.302  -1.060  -1.184  -1.110
287   F        -0.505  -0.491  -0.461  -0.573  -0.537  -0.470  -0.747  -0.703  -0.647
288   A        -0.378  -0.499  -0.476  -0.468  -0.658  -0.618  -0.538  -0.713  -0.668
289   S        -1.689  -1.684  -1.607  -1.617  -1.638  -1.511  -1.373  -1.372  -1.231
290   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
291   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
292   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
304   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   G         1.161   1.170   1.236   1.105   1.109   1.223   1.236   1.251   1.347
307   D        -1.022  -0.975  -0.953  -1.203  -1.108  -1.091  -1.081  -1.017  -0.957
308   N        -1.360  -1.245  -1.306  -1.101  -0.929  -1.086  -1.217  -1.107  -1.115
309   N        -0.811  -0.590  -0.900  -0.684  -0.374  -0.853  -0.808  -0.544  -0.898
310   T        -1.360  -1.379  -1.310  -1.221  -1.263  -1.175  -1.217  -1.243  -1.118
311   A        -0.811  -0.590  -0.900  -0.582  -0.279  -0.750  -0.808  -0.544  -0.898
312   S        -0.200  -0.052  -0.389  -0.167   0.025  -0.462  -0.263  -0.065  -0.541
313   N        -0.568  -0.482  -0.470  -0.617  -0.481  -0.476  -0.805  -0.687  -0.657
314   M        -1.590  -1.535  -1.348  -1.574  -1.530  -1.223  -1.435  -1.380  -1.151
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   L        -2.097  -2.020  -1.869  -2.085  -1.975  -1.752  -1.581  -1.518  -1.318
325   G        -1.801  -1.682  -1.612  -1.699  -1.512  -1.453  -1.477  -1.378  -1.236
326   S        -1.393  -1.305  -1.304  -1.297  -1.173  -1.164  -1.268  -1.194  -1.115
327   N        -0.913  -0.760  -0.917  -1.007  -0.812  -1.027  -0.955  -0.802  -0.921
328   E        -1.393  -1.353  -1.305  -1.432  -1.387  -1.257  -1.268  -1.229  -1.116
329   D        -1.393  -1.430  -1.323  -1.421  -1.465  -1.293  -1.268  -1.297  -1.131
330   V        -1.393  -1.325  -1.303  -1.317  -1.240  -1.175  -1.268  -1.207  -1.115
331   M        -1.488  -1.518  -1.341  -1.378  -1.427  -1.172  -1.353  -1.366  -1.145
332   M         0.306   0.257   0.205   0.476   0.398   0.286   0.167   0.076  -0.058
333   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
335   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
336   E        -0.811  -0.727  -0.900  -0.738  -0.630  -0.882  -0.808  -0.717  -0.898
337   Q        -1.827  -1.758  -1.619  -1.673  -1.586  -1.365  -1.490  -1.429  -1.240
338   D        -1.097  -0.977  -0.948  -1.234  -1.046  -1.002  -1.164  -1.042  -0.954
339   P         0.517   0.438   0.273   0.640   0.532   0.302   0.505   0.379   0.068
340   Y         1.161   1.170   1.236   1.269   1.281   1.374   1.236   1.251   1.347
341   S        -0.097  -0.075  -0.368   0.013   0.037  -0.370  -0.121  -0.104  -0.512
342   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
346   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
347   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
348   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
350   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
353   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
354   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
355   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
356   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
362   G         1.161   1.170   1.236   1.113   1.124   1.231   1.236   1.251   1.347
363   Y        -0.985  -1.042  -0.950  -1.010  -1.098  -0.964  -1.060  -1.100  -0.955
364   D        -1.505  -1.508  -1.327  -1.594  -1.578  -1.310  -1.373  -1.359  -1.135
365   N        -1.393  -1.316  -1.291  -1.401  -1.271  -1.271  -1.268  -1.186  -1.104
366   A        -1.393  -1.428  -1.324  -1.369  -1.422  -1.229  -1.268  -1.296  -1.132
367   W         1.161   1.170   1.236   1.347   1.356   1.445   1.236   1.251   1.347
368   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P16370
Output conservation file - output/P16370
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
