1     M         0.933   0.939   1.004   1.220   1.227   1.293   0.967   0.976   1.068
2     S         0.163   0.193  -0.152   0.210   0.251  -0.312   0.160   0.202  -0.355
3     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    N        -1.223  -1.199  -0.988  -1.312  -1.285  -1.033  -1.394  -1.363  -1.065
14    N         0.095   0.149  -0.164   0.371   0.436  -0.075   0.063   0.139  -0.375
15    S         0.163   0.193  -0.152   0.210   0.251  -0.312   0.160   0.202  -0.355
16    L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
17    E         0.163   0.221  -0.147   0.206   0.282  -0.233   0.160   0.240  -0.347
18    Q         0.163   0.198  -0.152   0.439   0.486  -0.125   0.160   0.208  -0.354
19    L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
20    K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
21    A         0.163   0.193  -0.152   0.010   0.055  -0.407   0.160   0.202  -0.355
22    S        -0.907  -0.830  -0.934  -0.912  -0.793  -1.039  -0.993  -0.893  -0.998
23    G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
24    T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
25    V        -0.419  -0.368  -0.246  -0.582  -0.492  -0.339  -0.762  -0.677  -0.516
26    V        -0.216  -0.150  -0.209  -0.253  -0.151  -0.304  -0.417  -0.312  -0.451
27    V         0.933   0.939   1.004   0.945   0.954   1.057   0.967   0.976   1.068
28    A        -1.633  -1.715  -1.496  -1.708  -1.775  -1.422  -1.570  -1.631  -1.320
29    D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
30    T         0.163   0.031  -0.164   0.277   0.112  -0.216   0.160  -0.031  -0.375
31    G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
32    D        -0.419  -0.369  -0.243  -0.637  -0.545  -0.388  -0.762  -0.679  -0.512
33    F         0.933   0.939   1.004   1.049   1.055   1.146   0.967   0.976   1.068
34    G        -0.571  -0.668  -0.911  -0.467  -0.609  -1.020  -0.532  -0.662  -0.968
35    S        -0.571  -0.620  -0.907  -0.359  -0.437  -0.826  -0.532  -0.605  -0.963
36    I         0.163   0.031  -0.164   0.252   0.098  -0.139   0.160  -0.031  -0.375
37    A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
38    K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
39    F        -0.419  -0.380  -0.242  -0.386  -0.323  -0.163  -0.762  -0.697  -0.510
40    Q        -1.192  -1.132  -0.976  -1.326  -1.241  -1.006  -1.339  -1.260  -1.049
41    P         0.933   0.939   1.004   1.120   1.126   1.207   0.967   0.976   1.068
42    Q         0.933   0.939   1.004   1.124   1.135   1.211   0.967   0.976   1.068
43    D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
44    S        -0.216  -0.165  -0.208  -0.515  -0.431  -0.499  -0.417  -0.336  -0.450
45    T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
46    T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
47    N         0.933   0.939   1.004   1.101   1.106   1.191   0.967   0.976   1.068
48    P         0.933   0.939   1.004   1.120   1.126   1.207   0.967   0.976   1.068
49    S         0.933   0.939   1.004   0.896   0.905   1.014   0.967   0.976   1.068
50    L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
51    I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
52    L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
53    A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
54    A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
55    A        -1.058  -0.971  -0.955  -1.318  -1.182  -1.124  -1.224  -1.123  -1.026
56    K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
57    Q        -1.058  -0.971  -0.955  -1.100  -1.004  -0.897  -1.224  -1.123  -1.026
58    P        -0.571  -0.515  -0.900  -0.180  -0.113  -0.749  -0.532  -0.462  -0.954
59    T        -1.546  -1.524  -1.480  -1.569  -1.510  -1.465  -1.454  -1.421  -1.305
60    Y         0.933   0.939   1.004   1.099   1.107   1.189   0.967   0.976   1.068
61    A         0.163   0.031  -0.164   0.024  -0.131  -0.387   0.160  -0.031  -0.375
62    K        -0.907  -0.917  -0.952  -1.119  -1.190  -1.221  -0.993  -1.038  -1.021
63    L         0.163   0.246  -0.146   0.136   0.230  -0.283   0.160   0.273  -0.345
64    I        -0.571  -0.734  -0.920  -0.453  -0.683  -1.005  -0.532  -0.742  -0.979
65    D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
66    V        -2.121  -2.083  -1.903  -2.136  -2.133  -1.889  -1.800  -1.772  -1.486
67    A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
68    V        -0.419  -0.422  -0.253  -0.620  -0.636  -0.397  -0.762  -0.771  -0.530
69    E        -2.121  -2.145  -1.904  -2.038  -2.103  -1.763  -1.800  -1.817  -1.486
70    Y        -0.571  -0.656  -0.916  -0.171  -0.294  -0.725  -0.532  -0.647  -0.973
71    G        -0.419  -0.380  -0.242  -0.798  -0.734  -0.498  -0.762  -0.697  -0.510
72    K         0.163   0.193  -0.152   0.146   0.183  -0.233   0.160   0.202  -0.355
73    K        -1.546  -1.506  -1.476  -1.641  -1.583  -1.576  -1.454  -1.401  -1.301
74    H        -1.546  -1.583  -1.483  -1.371  -1.423  -1.232  -1.454  -1.483  -1.307
75    G        -0.571  -0.656  -0.916  -0.272  -0.384  -0.787  -0.532  -0.647  -0.973
76    K        -1.767  -1.747  -1.506  -1.789  -1.764  -1.395  -1.685  -1.667  -1.329
77    T        -1.767  -1.698  -1.497  -1.698  -1.610  -1.333  -1.685  -1.612  -1.321
78    T        -1.546  -1.489  -1.479  -1.282  -1.219  -1.282  -1.454  -1.398  -1.305
79    E        -1.633  -1.624  -1.486  -1.721  -1.693  -1.446  -1.570  -1.553  -1.311
80    E         0.163   0.119  -0.156   0.202   0.154  -0.262   0.160   0.098  -0.362
81    Q        -0.419  -0.422  -0.253  -0.508  -0.526  -0.327  -0.762  -0.771  -0.530
82    V        -1.546  -1.495  -1.472  -1.548  -1.456  -1.495  -1.454  -1.391  -1.297
83    E        -1.261  -1.315  -1.460  -1.031  -1.111  -1.332  -1.108  -1.174  -1.284
84    N        -0.907  -0.922  -0.951  -0.986  -1.041  -1.074  -0.993  -1.025  -1.021
85    A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
86    V        -1.058  -1.064  -0.961  -1.211  -1.212  -1.008  -1.224  -1.216  -1.033
87    D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
88    R        -1.261  -1.311  -1.459  -0.752  -0.824  -1.129  -1.108  -1.170  -1.283
89    L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
90    L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
91    V        -0.419  -0.393  -0.249  -0.620  -0.578  -0.387  -0.762  -0.720  -0.522
92    E         0.163   0.031  -0.164   0.235   0.085  -0.181   0.160  -0.031  -0.375
93    F         0.933   0.939   1.004   1.049   1.055   1.146   0.967   0.976   1.068
94    G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
95    K        -0.907  -0.878  -0.946  -1.014  -0.981  -1.070  -0.993  -0.963  -1.014
96    E        -1.546  -1.519  -1.481  -1.591  -1.602  -1.537  -1.454  -1.448  -1.306
97    I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
98    L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
99    K        -1.261  -1.342  -1.459  -1.219  -1.352  -1.588  -1.108  -1.206  -1.283
100   I         0.163   0.198  -0.152   0.211   0.251  -0.232   0.160   0.208  -0.354
101   V         0.933   0.939   1.004   0.945   0.954   1.057   0.967   0.976   1.068
102   P         0.933   0.939   1.004   1.120   1.126   1.207   0.967   0.976   1.068
103   G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
104   R         0.163   0.031  -0.164   0.457   0.281  -0.111   0.160  -0.031  -0.375
105   V         0.933   0.939   1.004   0.945   0.954   1.057   0.967   0.976   1.068
106   S         0.933   0.939   1.004   0.896   0.905   1.014   0.967   0.976   1.068
107   T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
108   E         0.933   0.939   1.004   0.855   0.870   0.979   0.967   0.976   1.068
109   V         0.933   0.939   1.004   0.945   0.954   1.057   0.967   0.976   1.068
110   D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
111   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
112   R         0.163   0.031  -0.164   0.444   0.264  -0.149   0.160  -0.031  -0.375
113   L         0.163   0.119  -0.156   0.159   0.106  -0.235   0.160   0.098  -0.362
114   S         0.933   0.939   1.004   0.896   0.905   1.014   0.967   0.976   1.068
115   F         0.933   0.939   1.004   1.049   1.055   1.146   0.967   0.976   1.068
116   D         0.163   0.193  -0.152   0.305   0.340  -0.115   0.160   0.202  -0.355
117   T        -0.419  -0.446  -0.258  -0.742  -0.789  -0.480  -0.762  -0.815  -0.537
118   Q        -1.767  -1.800  -1.503  -1.741  -1.784  -1.404  -1.685  -1.703  -1.327
119   A         0.163   0.119  -0.156   0.015  -0.029  -0.400   0.160   0.098  -0.362
120   T         0.163   0.031  -0.164   0.277   0.112  -0.216   0.160  -0.031  -0.375
121   I        -0.419  -0.421  -0.254  -0.652  -0.663  -0.407  -0.762  -0.769  -0.531
122   E        -1.546  -1.601  -1.485  -1.677  -1.756  -1.627  -1.454  -1.512  -1.310
123   K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
124   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
125   R        -0.907  -0.891  -0.945  -0.926  -0.912  -0.969  -0.993  -0.978  -1.013
126   H        -1.279  -1.234  -0.992  -1.180  -1.093  -0.789  -1.454  -1.399  -1.069
127   I        -0.419  -0.393  -0.249  -0.739  -0.699  -0.491  -0.762  -0.720  -0.522
128   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
129   K        -0.216  -0.143  -0.214  -0.405  -0.293  -0.417  -0.417  -0.299  -0.461
130   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
131   F         0.163   0.193  -0.151   0.467   0.501  -0.001   0.160   0.201  -0.353
132   E        -0.216  -0.143  -0.214  -0.371  -0.246  -0.428  -0.417  -0.299  -0.461
133   Q        -1.546  -1.441  -1.472  -1.601  -1.458  -1.469  -1.454  -1.335  -1.298
134   E        -1.546  -1.439  -1.471  -1.436  -1.285  -1.365  -1.454  -1.330  -1.297
135   G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
136   V         0.163   0.193  -0.151   0.211   0.245  -0.231   0.160   0.201  -0.353
137   S        -0.571  -0.539  -0.898  -0.394  -0.356  -0.893  -0.532  -0.496  -0.952
138   K        -0.571  -0.576  -0.907  -0.494  -0.497  -0.931  -0.532  -0.540  -0.962
139   E        -0.907  -0.868  -0.945  -0.886  -0.844  -0.995  -0.993  -0.954  -1.013
140   R         0.933   0.939   1.004   1.128   1.137   1.214   0.967   0.976   1.068
141   V        -0.484  -0.469  -0.258  -0.762  -0.745  -0.412  -0.878  -0.857  -0.539
142   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
143   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
144   K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
145   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
146   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
147   S         0.933   0.939   1.004   0.896   0.905   1.014   0.967   0.976   1.068
148   T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
149   W        -0.216  -0.217  -0.225   0.119   0.112   0.003  -0.417  -0.421  -0.481
150   E         0.933   0.939   1.004   0.855   0.870   0.979   0.967   0.976   1.068
151   G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
152   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
153   Q         0.163   0.031  -0.164   0.453   0.278  -0.114   0.160  -0.031  -0.375
154   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
155   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
156   K        -1.633  -1.671  -1.487  -1.530  -1.598  -1.320  -1.570  -1.595  -1.312
157   E        -0.571  -0.734  -0.920  -0.412  -0.622  -0.903  -0.532  -0.742  -0.979
158   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
159   E         0.163   0.031  -0.164   0.235   0.085  -0.181   0.160  -0.031  -0.375
160   E        -1.425  -1.497  -1.480  -1.254  -1.350  -1.407  -1.292  -1.376  -1.304
161   K        -0.907  -1.019  -0.956  -1.038  -1.191  -1.112  -0.993  -1.124  -1.027
162   D        -0.571  -0.588  -0.906  -0.067  -0.095  -0.682  -0.532  -0.555  -0.962
163   G         0.163   0.198  -0.152   0.341   0.381  -0.133   0.160   0.208  -0.354
164   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
165   H         0.163   0.031  -0.164   0.610   0.447   0.101   0.160  -0.031  -0.375
166   C         0.163   0.198  -0.152   0.593   0.633   0.069   0.160   0.208  -0.354
167   N         0.933   0.939   1.004   1.101   1.106   1.191   0.967   0.976   1.068
168   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
169   T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
170   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
171   L         0.163   0.031  -0.164   0.178   0.024  -0.196   0.160  -0.031  -0.375
172   F         0.933   0.939   1.004   1.049   1.055   1.146   0.967   0.976   1.068
173   S         0.163   0.221  -0.147   0.273   0.339  -0.133   0.160   0.240  -0.347
174   F         0.163   0.031  -0.164   0.380   0.201  -0.167   0.160  -0.031  -0.375
175   V        -1.058  -1.116  -0.957  -1.275  -1.319  -1.099  -1.224  -1.266  -1.029
176   Q         0.933   0.939   1.004   1.124   1.135   1.211   0.967   0.976   1.068
177   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
178   V         0.163   0.031  -0.164   0.287   0.115  -0.220   0.160  -0.031  -0.375
179   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
180   C        -0.216  -0.272  -0.238  -0.024  -0.138  -0.247  -0.417  -0.513  -0.503
181   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
182   E         0.933   0.939   1.004   0.855   0.870   0.979   0.967   0.976   1.068
183   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
184   Q        -1.767  -1.739  -1.501  -1.631  -1.601  -1.280  -1.685  -1.656  -1.325
185   V        -0.571  -0.643  -0.909  -0.398  -0.514  -1.000  -0.532  -0.631  -0.965
186   T         0.163   0.031  -0.164   0.299   0.141  -0.154   0.160  -0.031  -0.375
187   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
188   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
189   S         0.933   0.939   1.004   0.896   0.905   1.014   0.967   0.976   1.068
190   P         0.933   0.939   1.004   1.120   1.126   1.207   0.967   0.976   1.068
191   F         0.933   0.939   1.004   1.049   1.055   1.146   0.967   0.976   1.068
192   V         0.933   0.939   1.004   0.945   0.954   1.057   0.967   0.976   1.068
193   G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
194   R         0.933   0.939   1.004   1.128   1.137   1.214   0.967   0.976   1.068
195   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
196   L         0.163   0.221  -0.147   0.178   0.239  -0.173   0.160   0.240  -0.347
197   D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
198   W        -0.571  -0.562  -0.900   0.007   0.011  -0.529  -0.532  -0.523  -0.953
199   Y        -0.907  -0.921  -0.952  -0.591  -0.639  -0.677  -0.993  -1.029  -1.022
200   K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
201   S         0.163   0.193  -0.151   0.010   0.054  -0.406   0.160   0.201  -0.353
202   S        -1.546  -1.603  -1.484  -1.518  -1.579  -1.460  -1.454  -1.510  -1.309
203   T         0.163   0.119  -0.156   0.307   0.260  -0.120   0.160   0.098  -0.362
204   G         0.163   0.119  -0.156   0.366   0.313  -0.074   0.160   0.098  -0.362
205   K        -1.058  -1.054  -0.953  -1.266  -1.235  -1.028  -1.224  -1.200  -1.024
206   D        -1.767  -1.806  -1.502  -1.755  -1.786  -1.372  -1.685  -1.709  -1.326
207   Y         0.933   0.939   1.004   1.099   1.107   1.189   0.967   0.976   1.068
208   K        -1.546  -1.591  -1.479  -1.470  -1.534  -1.444  -1.454  -1.493  -1.304
209   G        -1.058  -1.126  -0.959  -1.341  -1.429  -1.167  -1.224  -1.281  -1.032
210   E        -0.571  -0.576  -0.907  -0.443  -0.438  -0.956  -0.532  -0.540  -0.962
211   A        -1.058  -1.045  -0.963  -1.225  -1.218  -1.122  -1.224  -1.216  -1.036
212   D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
213   P         0.933   0.939   1.004   1.120   1.126   1.207   0.967   0.976   1.068
214   G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
215   V         0.933   0.939   1.004   0.945   0.954   1.057   0.967   0.976   1.068
216   I        -1.900  -1.928  -1.884  -1.711  -1.794  -1.783  -1.570  -1.601  -1.470
217   S         0.933   0.939   1.004   0.896   0.905   1.014   0.967   0.976   1.068
218   V         0.933   0.939   1.004   0.945   0.954   1.057   0.967   0.976   1.068
219   K        -0.907  -0.903  -0.941  -0.935  -0.924  -0.961  -0.993  -0.976  -1.008
220   K        -2.255  -2.261  -1.913  -2.317  -2.300  -1.836  -1.916  -1.909  -1.493
221   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
222   Y        -0.484  -0.463  -0.256  -0.513  -0.487  -0.194  -0.878  -0.845  -0.535
223   N         0.163   0.206  -0.153   0.452   0.500  -0.049   0.160   0.219  -0.356
224   Y         0.933   0.939   1.004   1.099   1.107   1.189   0.967   0.976   1.068
225   Y         0.933   0.939   1.004   1.099   1.107   1.189   0.967   0.976   1.068
226   K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
227   K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
228   Y        -1.058  -1.041  -0.963  -0.854  -0.854  -0.697  -1.224  -1.212  -1.037
229   G         0.163   0.206  -0.153   0.341   0.391  -0.136   0.160   0.219  -0.356
230   Y         0.933   0.939   1.004   1.099   1.107   1.189   0.967   0.976   1.068
231   K        -0.571  -0.515  -0.900  -0.493  -0.426  -0.920  -0.532  -0.462  -0.954
232   T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
233   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
234   V         0.933   0.939   1.004   0.945   0.954   1.057   0.967   0.976   1.068
235   M         0.933   0.939   1.004   1.220   1.227   1.293   0.967   0.976   1.068
236   G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
237   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
238   S         0.933   0.939   1.004   0.896   0.905   1.014   0.967   0.976   1.068
239   F         0.933   0.939   1.004   1.049   1.055   1.146   0.967   0.976   1.068
240   R         0.933   0.939   1.004   1.128   1.137   1.214   0.967   0.976   1.068
241   S         0.163   0.193  -0.151   0.448   0.480  -0.057   0.160   0.201  -0.353
242   T        -1.192  -1.218  -0.991  -1.295  -1.351  -1.046  -1.339  -1.373  -1.067
243   D        -0.216  -0.165  -0.208  -0.187  -0.112  -0.236  -0.417  -0.336  -0.450
244   E         0.933   0.939   1.004   0.855   0.870   0.979   0.967   0.976   1.068
245   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
246   K         0.163   0.031  -0.164   0.116  -0.047  -0.333   0.160  -0.031  -0.375
247   N        -1.058  -1.045  -0.963  -1.356  -1.334  -1.109  -1.224  -1.216  -1.036
248   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
249   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
250   G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
251   V        -0.484  -0.469  -0.258  -0.483  -0.462  -0.169  -0.878  -0.857  -0.539
252   D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
253   Y        -0.419  -0.427  -0.255  -0.403  -0.425  -0.192  -0.762  -0.781  -0.532
254   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
255   T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
256   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
257   S         0.163   0.193  -0.152   0.210   0.251  -0.312   0.160   0.202  -0.355
258   P         0.933   0.939   1.004   1.120   1.126   1.207   0.967   0.976   1.068
259   A        -1.767  -1.751  -1.504  -1.920  -1.899  -1.510  -1.685  -1.672  -1.328
260   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
261   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
262   D        -0.419  -0.380  -0.242  -0.663  -0.593  -0.398  -0.762  -0.697  -0.510
263   K        -1.058  -1.017  -0.954  -1.097  -1.039  -0.956  -1.224  -1.171  -1.026
264   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
265   M        -1.546  -1.516  -1.472  -1.372  -1.336  -1.200  -1.454  -1.411  -1.297
266   N         0.163   0.198  -0.152   0.448   0.486  -0.058   0.160   0.208  -0.354
267   S         0.933   0.939   1.004   0.896   0.905   1.014   0.967   0.976   1.068
268   T        -1.192  -1.191  -0.986  -1.197  -1.210  -0.928  -1.339  -1.340  -1.062
269   E        -1.058  -1.135  -0.960  -1.242  -1.350  -1.119  -1.224  -1.294  -1.034
270   P        -1.261  -1.210  -1.448  -0.862  -0.805  -1.311  -1.108  -1.053  -1.272
271   F         0.163   0.193  -0.151   0.314   0.349  -0.121   0.160   0.201  -0.353
272   P         0.163   0.198  -0.152   0.435   0.477  -0.129   0.160   0.208  -0.354
273   R        -0.907  -0.928  -0.949  -0.891  -0.926  -0.884  -0.993  -1.034  -1.018
274   V        -1.546  -1.430  -1.473  -1.560  -1.408  -1.417  -1.454  -1.327  -1.298
275   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
276   D        -0.571  -0.656  -0.916  -0.311  -0.422  -0.779  -0.532  -0.647  -0.973
277   P        -1.058  -1.010  -0.956  -1.227  -1.170  -1.042  -1.224  -1.161  -1.027
278   V        -2.121  -2.060  -1.894  -2.214  -2.134  -1.869  -1.800  -1.746  -1.478
279   S        -1.767  -1.798  -1.504  -1.874  -1.914  -1.507  -1.685  -1.700  -1.328
280   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
281   K        -1.261  -1.384  -1.463  -1.173  -1.369  -1.501  -1.108  -1.249  -1.287
282   K        -1.767  -1.691  -1.500  -1.972  -1.843  -1.616  -1.685  -1.602  -1.324
283   E        -1.058  -1.044  -0.963  -1.279  -1.279  -1.108  -1.224  -1.215  -1.036
284   A        -2.121  -2.172  -1.908  -2.038  -2.107  -1.735  -1.800  -1.834  -1.489
285   G        -2.609  -2.552  -2.247  -2.464  -2.409  -2.027  -2.031  -1.983  -1.603
286   D         0.163   0.193  -0.151   0.206   0.249  -0.240   0.160   0.201  -0.353
287   K         0.163   0.198  -0.152   0.146   0.189  -0.230   0.160   0.208  -0.354
288   I        -0.907  -0.928  -0.949  -0.911  -0.972  -1.051  -0.993  -1.034  -1.018
289   S        -1.058  -1.023  -0.955  -1.206  -1.160  -1.082  -1.224  -1.187  -1.028
290   Y        -0.216  -0.162  -0.213  -0.044   0.034  -0.108  -0.417  -0.331  -0.458
291   I        -1.192  -1.136  -0.977  -1.392  -1.314  -1.104  -1.339  -1.267  -1.050
292   S        -1.546  -1.589  -1.484  -1.355  -1.425  -1.302  -1.454  -1.505  -1.310
293   D        -1.546  -1.577  -1.478  -1.372  -1.421  -1.323  -1.454  -1.477  -1.303
294   E         0.933   0.939   1.004   0.855   0.870   0.979   0.967   0.976   1.068
295   S        -1.058  -1.000  -0.954  -1.040  -0.938  -0.950  -1.224  -1.146  -1.025
296   K        -2.121  -2.116  -1.901  -2.293  -2.261  -1.977  -1.800  -1.786  -1.484
297   F         0.933   0.939   1.004   1.049   1.055   1.146   0.967   0.976   1.068
298   R         0.933   0.939   1.004   1.128   1.137   1.214   0.967   0.976   1.068
299   F        -0.571  -0.507  -0.901  -0.180  -0.109  -0.646  -0.532  -0.452  -0.955
300   D        -1.546  -1.446  -1.470  -1.600  -1.423  -1.568  -1.454  -1.336  -1.296
301   L        -0.484  -0.463  -0.256  -0.739  -0.695  -0.379  -0.878  -0.845  -0.535
302   N         0.933   0.939   1.004   1.101   1.106   1.191   0.967   0.976   1.068
303   E        -0.571  -0.562  -0.900  -0.404  -0.388  -0.854  -0.532  -0.523  -0.953
304   D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
305   A        -0.907  -0.986  -0.958  -1.040  -1.139  -1.064  -0.993  -1.098  -1.029
306   M         0.933   0.939   1.004   1.220   1.227   1.293   0.967   0.976   1.068
307   A         0.933   0.939   1.004   0.664   0.681   0.815   0.967   0.976   1.068
308   T        -0.216  -0.309  -0.240  -0.239  -0.392  -0.331  -0.417  -0.574  -0.506
309   E        -0.571  -0.562  -0.900  -0.431  -0.417  -0.915  -0.532  -0.523  -0.953
310   K         0.933   0.939   1.004   0.765   0.776   0.902   0.967   0.976   1.068
311   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
312   S         0.163   0.031  -0.164   0.277   0.121  -0.148   0.160  -0.031  -0.375
313   E        -1.546  -1.481  -1.471  -1.448  -1.358  -1.332  -1.454  -1.379  -1.297
314   G         0.933   0.939   1.004   0.990   0.996   1.095   0.967   0.976   1.068
315   I         0.933   0.939   1.004   0.857   0.864   0.981   0.967   0.976   1.068
316   R        -0.571  -0.734  -0.920  -0.208  -0.438  -0.871  -0.532  -0.742  -0.979
317   K        -1.261  -1.210  -1.448  -1.125  -1.076  -1.387  -1.108  -1.053  -1.272
318   F         0.933   0.939   1.004   1.049   1.055   1.146   0.967   0.976   1.068
319   S        -1.058  -0.971  -0.955  -1.354  -1.242  -1.129  -1.224  -1.123  -1.026
320   A        -0.419  -0.396  -0.249  -0.925  -0.881  -0.639  -0.762  -0.726  -0.522
321   D         0.933   0.939   1.004   0.928   0.937   1.042   0.967   0.976   1.068
322   I        -1.058  -1.010  -0.956  -1.323  -1.257  -1.048  -1.224  -1.161  -1.027
323   V        -0.571  -0.562  -0.900  -0.355  -0.347  -0.882  -0.532  -0.523  -0.953
324   T         0.933   0.939   1.004   0.930   0.943   1.044   0.967   0.976   1.068
325   L         0.933   0.939   1.004   0.782   0.788   0.917   0.967   0.976   1.068
326   F        -2.121  -2.163  -1.910  -1.926  -1.997  -1.694  -1.800  -1.826  -1.490
327   D        -1.546  -1.595  -1.485  -1.481  -1.558  -1.471  -1.454  -1.501  -1.311
328   L        -2.121  -2.049  -1.898  -1.992  -1.931  -1.637  -1.800  -1.746  -1.482
329   I        -0.419  -0.396  -0.249  -0.739  -0.706  -0.491  -0.762  -0.726  -0.522
330   E        -0.419  -0.445  -0.257  -0.751  -0.812  -0.524  -0.762  -0.813  -0.537
331   K        -2.121  -2.098  -1.898  -2.224  -2.166  -1.847  -1.800  -1.775  -1.481
332   K        -0.216  -0.150  -0.209  -0.337  -0.245  -0.310  -0.417  -0.312  -0.451
333   V        -1.767  -1.690  -1.499  -1.823  -1.731  -1.449  -1.685  -1.601  -1.323
334   T        -2.639  -2.619  -2.248  -2.603  -2.615  -2.078  -2.045  -2.024  -1.603
335   A         0.012  -0.077  -0.188  -0.195  -0.323  -0.483  -0.058  -0.196  -0.416
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P15019
Output conservation file - output/P15019
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
