1     M         1.012   1.021   1.043   1.168   1.186   1.206   1.056   1.067   1.094
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    A        -0.201  -0.082  -0.314  -0.179  -0.005  -0.361  -0.302  -0.121  -0.478
27    R        -0.201  -0.271  -0.335  -0.064  -0.170  -0.264  -0.302  -0.408  -0.512
28    T         1.012   1.021   1.043   1.075   1.087   1.119   1.056   1.067   1.094
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    I        -0.201  -0.271  -0.335  -0.379  -0.508  -0.647  -0.302  -0.408  -0.512
32    T        -0.201  -0.271  -0.335  -0.089  -0.197  -0.302  -0.302  -0.408  -0.512
33    F        -0.201  -0.106  -0.317  -0.041   0.094  -0.226  -0.302  -0.157  -0.482
34    D        -1.230  -1.294  -1.224  -1.217  -1.310  -1.194  -1.207  -1.271  -1.162
35    I        -0.201  -0.271  -0.335  -0.379  -0.508  -0.647  -0.302  -0.408  -0.512
36    P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
37    S        -1.230  -1.294  -1.224  -1.232  -1.335  -1.229  -1.207  -1.271  -1.162
38    Q        -1.230  -1.082  -1.198  -1.113  -0.900  -1.034  -1.207  -1.016  -1.132
39    Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
40    K        -1.230  -1.212  -1.205  -1.190  -1.167  -1.133  -1.207  -1.177  -1.140
41    L        -0.201  -0.271  -0.335  -0.445  -0.534  -0.585  -0.302  -0.408  -0.512
42    V        -0.201  -0.271  -0.335  -0.135  -0.250  -0.383  -0.302  -0.408  -0.512
43    D        -0.201  -0.271  -0.335  -0.171  -0.272  -0.372  -0.302  -0.408  -0.512
44    L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
45    I        -0.483  -0.466  -0.394  -0.674  -0.643  -0.516  -0.754  -0.724  -0.608
46    G         1.012   1.021   1.043   1.168   1.179   1.206   1.056   1.067   1.094
47    E        -0.201  -0.271  -0.335  -0.165  -0.256  -0.349  -0.302  -0.408  -0.512
48    G         1.012   1.021   1.043   1.168   1.179   1.206   1.056   1.067   1.094
49    A        -0.201  -0.254  -0.339  -0.170  -0.256  -0.392  -0.302  -0.381  -0.517
50    Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
51    G         1.012   1.021   1.043   1.168   1.179   1.206   1.056   1.067   1.094
52    T        -1.230  -1.294  -1.224  -1.170  -1.280  -1.171  -1.207  -1.271  -1.162
53    V         1.012   1.021   1.043   1.087   1.104   1.130   1.056   1.067   1.094
54    C         1.012   1.021   1.043   1.251   1.264   1.284   1.056   1.067   1.094
55    S        -0.201  -0.271  -0.335  -0.160  -0.270  -0.382  -0.302  -0.408  -0.512
56    A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
57    I        -1.230  -1.294  -1.224  -1.417  -1.539  -1.411  -1.207  -1.271  -1.162
58    H         1.012   1.021   1.043   1.172   1.184   1.209   1.056   1.067   1.094
59    K        -0.201  -0.254  -0.339  -0.312  -0.404  -0.596  -0.302  -0.381  -0.517
60    P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
61    S        -0.483  -0.466  -0.394  -0.600  -0.570  -0.448  -0.754  -0.724  -0.608
62    G        -0.201  -0.106  -0.317  -0.000   0.137  -0.196  -0.302  -0.157  -0.482
63    I        -1.977  -1.931  -1.833  -2.055  -2.002  -1.810  -1.659  -1.600  -1.459
64    K         1.012   1.021   1.043   0.981   1.000   1.031   1.056   1.067   1.094
65    V         1.012   1.021   1.043   1.087   1.104   1.130   1.056   1.067   1.094
66    A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
67    I        -0.201  -0.271  -0.335  -0.247  -0.349  -0.438  -0.302  -0.408  -0.512
68    K         1.012   1.021   1.043   0.981   1.000   1.031   1.056   1.067   1.094
69    K        -0.201  -0.254  -0.339  -0.185  -0.261  -0.394  -0.302  -0.381  -0.517
70    I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
71    Q        -1.230  -1.294  -1.224  -0.986  -1.086  -0.983  -1.207  -1.271  -1.162
72    P        -0.201  -0.254  -0.339  -0.145  -0.225  -0.350  -0.302  -0.381  -0.517
73    F        -0.201  -0.254  -0.339  -0.075  -0.164  -0.316  -0.302  -0.381  -0.517
74    S        -1.230  -1.294  -1.224  -1.175  -1.270  -1.158  -1.207  -1.271  -1.162
75    K        -1.977  -1.931  -1.833  -1.784  -1.699  -1.556  -1.659  -1.600  -1.459
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
87    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
88    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
89    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
90    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
91    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
92    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    K        -1.230  -1.212  -1.205  -1.236  -1.206  -1.185  -1.207  -1.177  -1.140
99    L        -1.230  -1.082  -1.198  -1.220  -0.957  -1.185  -1.207  -1.016  -1.132
100   F        -0.201  -0.254  -0.339  -0.074  -0.164  -0.314  -0.302  -0.381  -0.517
101   V        -1.230  -1.294  -1.224  -1.183  -1.293  -1.192  -1.207  -1.271  -1.162
102   T        -1.230  -1.294  -1.224  -1.344  -1.494  -1.388  -1.207  -1.271  -1.162
103   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
104   T         1.012   1.021   1.043   1.075   1.087   1.119   1.056   1.067   1.094
105   I        -0.483  -0.466  -0.395  -0.979  -0.950  -0.802  -0.754  -0.723  -0.608
106   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
107   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
108   I        -0.201  -0.106  -0.317  -0.379  -0.221  -0.607  -0.302  -0.157  -0.482
109   K         1.012   1.021   1.043   0.981   1.000   1.031   1.056   1.067   1.094
110   L        -0.201  -0.254  -0.339  -0.534  -0.615  -0.729  -0.302  -0.381  -0.517
111   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
112   R        -1.230  -1.202  -1.207  -1.166  -1.121  -1.137  -1.207  -1.164  -1.143
113   Y        -1.230  -1.082  -1.198  -0.991  -0.765  -0.946  -1.207  -1.016  -1.132
114   F         1.012   1.021   1.043   1.118   1.127   1.159   1.056   1.067   1.094
115   H        -0.361  -0.420  -0.382  -0.255  -0.366  -0.315  -0.553  -0.646  -0.587
116   E        -1.977  -1.931  -1.833  -1.832  -1.747  -1.601  -1.659  -1.600  -1.459
117   H         1.012   1.021   1.043   1.172   1.184   1.209   1.056   1.067   1.094
118   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
119   N         1.012   1.021   1.043   1.095   1.107   1.137   1.056   1.067   1.094
120   I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
121   I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
122   S        -0.201  -0.254  -0.339  -0.140  -0.217  -0.356  -0.302  -0.381  -0.517
123   I        -0.201  -0.106  -0.317  -0.247  -0.108  -0.409  -0.302  -0.157  -0.482
124   L        -0.201  -0.254  -0.339  -0.463  -0.534  -0.616  -0.302  -0.381  -0.517
125   D        -0.201  -0.254  -0.339  -0.212  -0.289  -0.442  -0.302  -0.381  -0.517
126   K        -0.483  -0.466  -0.395  -0.753  -0.720  -0.591  -0.754  -0.723  -0.608
127   V        -1.230  -1.294  -1.224  -1.333  -1.480  -1.380  -1.207  -1.271  -1.162
128   R        -1.230  -1.294  -1.224  -1.175  -1.289  -1.177  -1.207  -1.271  -1.162
129   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
130   V        -1.977  -1.931  -1.833  -1.741  -1.669  -1.515  -1.659  -1.600  -1.459
131   S        -0.201  -0.254  -0.339  -0.109  -0.179  -0.306  -0.302  -0.381  -0.517
132   I        -1.977  -1.931  -1.833  -1.741  -1.667  -1.515  -1.659  -1.600  -1.459
133   D        -1.977  -1.931  -1.833  -1.788  -1.716  -1.560  -1.659  -1.600  -1.459
134   K        -1.230  -1.294  -1.224  -1.224  -1.316  -1.200  -1.207  -1.271  -1.162
135   L        -0.483  -0.466  -0.394  -0.819  -0.791  -0.649  -0.754  -0.724  -0.608
136   N        -1.230  -1.185  -1.205  -1.229  -1.161  -1.174  -1.207  -1.146  -1.140
137   A        -1.230  -1.294  -1.224  -1.243  -1.351  -1.235  -1.207  -1.271  -1.162
138   V        -0.201  -0.254  -0.339  -0.135  -0.220  -0.389  -0.302  -0.381  -0.517
139   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
140   L        -0.201  -0.271  -0.335  -0.534  -0.643  -0.724  -0.302  -0.408  -0.512
141   V         1.012   1.021   1.043   1.087   1.104   1.130   1.056   1.067   1.094
142   E        -0.201  -0.082  -0.314  -0.036   0.151  -0.245  -0.302  -0.121  -0.478
143   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
144   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
145   M         1.012   1.021   1.043   1.168   1.186   1.206   1.056   1.067   1.094
146   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
147   T         1.012   1.021   1.043   1.075   1.087   1.119   1.056   1.067   1.094
148   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
149   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
150   Q        -1.230  -1.294  -1.224  -1.027  -1.131  -1.034  -1.207  -1.271  -1.162
151   K        -0.483  -0.444  -0.387  -0.634  -0.555  -0.461  -0.754  -0.687  -0.595
152   V        -0.483  -0.466  -0.394  -0.674  -0.643  -0.519  -0.754  -0.724  -0.608
153   I        -0.201  -0.254  -0.339  -0.379  -0.476  -0.654  -0.302  -0.381  -0.517
154   N        -1.230  -1.294  -1.224  -1.117  -1.228  -1.113  -1.207  -1.271  -1.162
155   N        -1.230  -1.082  -1.198  -1.097  -0.876  -1.030  -1.207  -1.016  -1.132
156   Q        -0.201  -0.254  -0.339  -0.017  -0.097  -0.263  -0.302  -0.381  -0.517
157   N         1.012   1.021   1.043   1.081   1.090   1.124   1.056   1.067   1.094
158   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
159   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
160   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
161   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
162   T        -0.361  -0.364  -0.363  -0.392  -0.399  -0.408  -0.553  -0.555  -0.556
163   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
164   S        -0.201  -0.254  -0.339  -0.140  -0.217  -0.356  -0.302  -0.381  -0.517
165   D        -1.230  -1.202  -1.207  -1.220  -1.163  -1.174  -1.207  -1.164  -1.143
166   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
167   H         1.012   1.021   1.043   1.172   1.184   1.209   1.056   1.067   1.094
168   V        -1.230  -1.196  -1.204  -1.161  -1.100  -1.080  -1.207  -1.160  -1.139
169   Q         1.012   1.021   1.043   1.172   1.188   1.209   1.056   1.067   1.094
170   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
171   F         1.012   1.021   1.043   1.118   1.127   1.159   1.056   1.067   1.094
172   T        -1.230  -1.202  -1.207  -1.267  -1.244  -1.254  -1.207  -1.164  -1.143
173   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
174   Q         1.012   1.021   1.043   1.172   1.188   1.209   1.056   1.067   1.094
175   I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
176   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
177   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
178   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
179   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
180   K         1.012   1.021   1.043   0.981   1.000   1.031   1.056   1.067   1.094
181   S        -0.483  -0.444  -0.387  -0.646  -0.580  -0.478  -0.754  -0.687  -0.595
182   I        -1.230  -1.212  -1.205  -1.374  -1.314  -1.325  -1.207  -1.177  -1.140
183   H         1.012   1.021   1.043   1.172   1.184   1.209   1.056   1.067   1.094
184   S         1.012   1.021   1.043   1.029   1.046   1.076   1.056   1.067   1.094
185   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
186   Q        -1.230  -1.294  -1.224  -1.026  -1.129  -1.032  -1.207  -1.271  -1.162
187   V         1.012   1.021   1.043   1.087   1.104   1.130   1.056   1.067   1.094
188   I        -0.201  -0.271  -0.335  -0.247  -0.349  -0.438  -0.302  -0.408  -0.512
189   H         1.012   1.021   1.043   1.172   1.184   1.209   1.056   1.067   1.094
190   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
191   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
192   I        -0.201  -0.082  -0.314  -0.534  -0.353  -0.690  -0.302  -0.121  -0.478
193   K         1.012   1.021   1.043   0.981   1.000   1.031   1.056   1.067   1.094
194   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
195   S         1.012   1.021   1.043   1.029   1.046   1.076   1.056   1.067   1.094
196   N         1.012   1.021   1.043   1.095   1.107   1.137   1.056   1.067   1.094
197   L        -0.201  -0.254  -0.339  -0.534  -0.615  -0.729  -0.302  -0.381  -0.517
198   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
199   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
200   N         1.012   1.021   1.043   1.095   1.107   1.137   1.056   1.067   1.094
201   S        -0.201  -0.271  -0.335  -0.160  -0.270  -0.382  -0.302  -0.408  -0.512
202   N         1.012   1.021   1.043   1.095   1.107   1.137   1.056   1.067   1.094
203   C         1.012   1.021   1.043   1.251   1.264   1.284   1.056   1.067   1.094
204   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
205   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
206   K         1.012   1.021   1.043   0.981   1.000   1.031   1.056   1.067   1.094
207   V        -0.201  -0.254  -0.339  -0.135  -0.220  -0.389  -0.302  -0.381  -0.517
208   C        -0.201  -0.271  -0.335   0.054  -0.064  -0.200  -0.302  -0.408  -0.512
209   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
210   F         1.012   1.021   1.043   1.118   1.127   1.159   1.056   1.067   1.094
211   G         1.012   1.021   1.043   1.168   1.179   1.206   1.056   1.067   1.094
212   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
213   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
214   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
215   C        -0.361  -0.420  -0.382  -0.192  -0.308  -0.266  -0.553  -0.646  -0.587
216   L        -0.361  -0.420  -0.382  -0.676  -0.747  -0.649  -0.553  -0.646  -0.587
217   A        -0.361  -0.420  -0.382  -0.420  -0.531  -0.475  -0.553  -0.646  -0.587
218   S        -0.361  -0.420  -0.382  -0.415  -0.516  -0.459  -0.553  -0.646  -0.587
219   S        -0.201  -0.254  -0.339  -0.168  -0.246  -0.399  -0.302  -0.381  -0.517
220   S        -1.230  -1.196  -1.204  -1.200  -1.144  -1.145  -1.207  -1.160  -1.139
221   D        -1.230  -1.212  -1.205  -1.138  -1.113  -1.076  -1.207  -1.177  -1.140
222   S        -0.483  -0.444  -0.387  -0.646  -0.580  -0.478  -0.754  -0.687  -0.595
223   R        -1.230  -1.294  -1.224  -1.086  -1.180  -1.068  -1.207  -1.271  -1.162
224   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
225   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   E        -0.483  -0.444  -0.387  -0.575  -0.484  -0.399  -0.754  -0.687  -0.595
228   T        -1.230  -1.196  -1.204  -1.052  -1.000  -1.004  -1.207  -1.160  -1.139
229   L        -1.230  -1.082  -1.198  -1.214  -0.954  -1.179  -1.207  -1.016  -1.132
230   V        -0.201  -0.271  -0.335  -0.105  -0.214  -0.336  -0.302  -0.408  -0.512
231   G         1.012   1.021   1.043   1.168   1.179   1.206   1.056   1.067   1.094
232   F         1.012   1.021   1.043   1.118   1.127   1.159   1.056   1.067   1.094
233   M        -0.201  -0.254  -0.339  -0.127  -0.222  -0.436  -0.302  -0.381  -0.517
234   T         1.012   1.021   1.043   1.075   1.087   1.119   1.056   1.067   1.094
235   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
236   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
237   V         1.012   1.021   1.043   1.087   1.104   1.130   1.056   1.067   1.094
238   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
239   T         1.012   1.021   1.043   1.075   1.087   1.119   1.056   1.067   1.094
240   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
241   W         1.012   1.021   1.043   1.274   1.289   1.305   1.056   1.067   1.094
242   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
243   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
244   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
245   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
246   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
247   I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
248   M         1.012   1.021   1.043   1.168   1.186   1.206   1.056   1.067   1.094
249   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
250   T        -1.230  -1.185  -1.205  -1.138  -1.069  -1.087  -1.207  -1.146  -1.140
251   F         1.012   1.021   1.043   1.118   1.127   1.159   1.056   1.067   1.094
252   Q        -0.201  -0.271  -0.335  -0.003  -0.111  -0.234  -0.302  -0.408  -0.512
253   E        -0.201  -0.254  -0.339  -0.225  -0.299  -0.448  -0.302  -0.381  -0.517
254   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
255   T        -0.483  -0.444  -0.387  -0.600  -0.534  -0.437  -0.754  -0.687  -0.595
256   T        -0.201  -0.271  -0.335  -0.125  -0.238  -0.359  -0.302  -0.408  -0.512
257   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
258   M        -0.483  -0.444  -0.387  -0.614  -0.567  -0.462  -0.754  -0.687  -0.595
259   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
260   I        -0.201  -0.271  -0.335  -0.379  -0.508  -0.647  -0.302  -0.408  -0.512
261   W         1.012   1.021   1.043   1.274   1.289   1.305   1.056   1.067   1.094
262   S         1.012   1.021   1.043   1.029   1.046   1.076   1.056   1.067   1.094
263   C        -0.201  -0.271  -0.335   0.073  -0.040  -0.170  -0.302  -0.408  -0.512
264   G         1.012   1.021   1.043   1.168   1.179   1.206   1.056   1.067   1.094
265   C         1.012   1.021   1.043   1.251   1.264   1.284   1.056   1.067   1.094
266   I        -0.201  -0.254  -0.339  -0.247  -0.322  -0.443  -0.302  -0.381  -0.517
267   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
268   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
269   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
270   M         1.012   1.021   1.043   1.168   1.186   1.206   1.056   1.067   1.094
271   V        -1.230  -1.082  -1.198  -1.517  -1.298  -1.413  -1.207  -1.016  -1.132
272   S        -1.230  -1.202  -1.207  -1.089  -1.046  -1.033  -1.207  -1.164  -1.143
273   G        -1.230  -1.294  -1.224  -1.055  -1.175  -1.066  -1.207  -1.271  -1.162
274   K        -0.201  -0.271  -0.335  -0.185  -0.288  -0.388  -0.302  -0.408  -0.512
275   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
276   L        -0.201  -0.254  -0.339  -0.534  -0.615  -0.729  -0.302  -0.381  -0.517
277   F         1.012   1.021   1.043   1.118   1.127   1.159   1.056   1.067   1.094
278   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
279   G         1.012   1.021   1.043   1.168   1.179   1.206   1.056   1.067   1.094
280   R        -0.201  -0.082  -0.314  -0.185  -0.009  -0.354  -0.302  -0.121  -0.478
281   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
282   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
283   H         1.012   1.021   1.043   1.172   1.184   1.209   1.056   1.067   1.094
284   H        -0.201  -0.271  -0.335  -0.017  -0.130  -0.257  -0.302  -0.408  -0.512
285   Q         1.012   1.021   1.043   1.172   1.188   1.209   1.056   1.067   1.094
286   L        -0.201  -0.271  -0.335  -0.534  -0.643  -0.724  -0.302  -0.408  -0.512
287   W        -1.230  -1.294  -1.224  -1.097  -1.241  -1.161  -1.207  -1.271  -1.162
288   L        -0.201  -0.106  -0.317  -0.534  -0.388  -0.694  -0.302  -0.157  -0.482
289   I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
290   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
291   E        -1.230  -1.294  -1.224  -1.225  -1.313  -1.197  -1.207  -1.271  -1.162
292   V        -1.230  -1.294  -1.224  -1.165  -1.278  -1.169  -1.207  -1.271  -1.162
293   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
294   G         1.012   1.021   1.043   1.168   1.179   1.206   1.056   1.067   1.094
295   T        -0.201  -0.106  -0.317  -0.110   0.031  -0.303  -0.302  -0.157  -0.482
296   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
297   S        -0.483  -0.466  -0.395  -0.600  -0.569  -0.448  -0.754  -0.723  -0.608
298   F        -1.977  -1.931  -1.833  -1.932  -1.832  -1.695  -1.659  -1.600  -1.459
299   E        -0.201  -0.271  -0.335  -0.225  -0.327  -0.442  -0.302  -0.408  -0.512
300   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
301   F        -0.201  -0.254  -0.339  -0.105  -0.197  -0.364  -0.302  -0.381  -0.517
302   N        -1.230  -1.196  -1.204  -1.208  -1.157  -1.149  -1.207  -1.160  -1.139
303   Q        -1.230  -1.294  -1.224  -1.052  -1.166  -1.063  -1.207  -1.271  -1.162
304   I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
305   K        -0.201  -0.254  -0.339  -0.179  -0.252  -0.384  -0.302  -0.381  -0.517
306   S        -0.201  -0.254  -0.339  -0.126  -0.200  -0.334  -0.302  -0.381  -0.517
307   K        -1.230  -1.294  -1.224  -1.173  -1.263  -1.138  -1.207  -1.271  -1.162
308   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
309   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
310   K        -0.201  -0.271  -0.335  -0.185  -0.288  -0.388  -0.302  -0.408  -0.512
311   E        -0.201  -0.271  -0.335  -0.228  -0.330  -0.446  -0.302  -0.408  -0.512
312   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
313   I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
314   A        -1.977  -1.931  -1.833  -2.093  -2.043  -1.845  -1.659  -1.600  -1.459
315   N        -1.230  -1.082  -1.198  -1.097  -0.876  -1.030  -1.207  -1.016  -1.132
316   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
317   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
318   M        -1.230  -1.294  -1.224  -0.972  -1.068  -0.964  -1.207  -1.271  -1.162
319   R        -1.977  -1.931  -1.833  -1.788  -1.712  -1.560  -1.659  -1.600  -1.459
320   P        -0.201  -0.106  -0.317  -0.189  -0.046  -0.381  -0.302  -0.157  -0.482
321   P        -1.230  -1.082  -1.198  -1.175  -0.950  -1.106  -1.207  -1.016  -1.132
322   L        -1.977  -1.931  -1.833  -2.117  -1.992  -1.867  -1.659  -1.600  -1.459
323   P        -1.230  -1.294  -1.224  -1.220  -1.321  -1.207  -1.207  -1.271  -1.162
324   W        -0.201  -0.271  -0.335   0.108  -0.001  -0.131  -0.302  -0.408  -0.512
325   E        -1.977  -1.931  -1.833  -1.930  -1.850  -1.692  -1.659  -1.600  -1.459
326   T        -1.977  -1.931  -1.833  -1.732  -1.666  -1.508  -1.659  -1.600  -1.459
327   V        -0.483  -0.444  -0.387  -0.843  -0.810  -0.685  -0.754  -0.687  -0.595
328   W        -1.230  -1.196  -1.204  -1.333  -1.294  -1.211  -1.207  -1.160  -1.139
329   S        -1.977  -1.931  -1.833  -1.761  -1.690  -1.534  -1.659  -1.600  -1.459
330   K        -1.230  -1.294  -1.224  -1.145  -1.222  -1.103  -1.207  -1.271  -1.162
331   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
332   D        -1.230  -1.212  -1.205  -1.253  -1.221  -1.207  -1.207  -1.177  -1.140
333   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   N        -0.201  -0.271  -0.335  -0.091  -0.202  -0.320  -0.302  -0.408  -0.512
335   P        -0.201  -0.254  -0.339  -0.193  -0.276  -0.426  -0.302  -0.381  -0.517
336   D        -1.230  -1.202  -1.207  -1.307  -1.229  -1.274  -1.207  -1.164  -1.143
337   M        -1.230  -1.185  -1.205  -1.286  -1.248  -1.252  -1.207  -1.146  -1.140
338   I        -0.201  -0.254  -0.339  -0.379  -0.476  -0.654  -0.302  -0.381  -0.517
339   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
340   L        -0.201  -0.254  -0.339  -0.534  -0.615  -0.729  -0.302  -0.381  -0.517
341   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
342   D        -1.230  -1.212  -1.205  -1.246  -1.216  -1.199  -1.207  -1.177  -1.140
343   K         1.012   1.021   1.043   0.981   1.000   1.031   1.056   1.067   1.094
344   M        -0.483  -0.444  -0.387  -0.780  -0.755  -0.631  -0.754  -0.687  -0.595
345   L        -0.201  -0.254  -0.339  -0.445  -0.510  -0.588  -0.302  -0.381  -0.517
346   Q        -1.230  -1.185  -1.205  -1.133  -1.082  -1.094  -1.207  -1.146  -1.140
347   F         1.012   1.021   1.043   1.118   1.127   1.159   1.056   1.067   1.094
348   N         1.012   1.021   1.043   1.095   1.107   1.137   1.056   1.067   1.094
349   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
350   D        -0.201  -0.254  -0.339  -0.208  -0.286  -0.436  -0.302  -0.381  -0.517
351   K        -0.201  -0.254  -0.339  -0.185  -0.261  -0.394  -0.302  -0.381  -0.517
352   R         1.012   1.021   1.043   1.075   1.085   1.119   1.056   1.067   1.094
353   I         1.012   1.021   1.043   0.914   0.928   0.968   1.056   1.067   1.094
354   S        -0.483  -0.444  -0.387  -0.600  -0.525  -0.432  -0.754  -0.687  -0.595
355   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
356   A        -1.230  -1.082  -1.198  -1.219  -0.986  -1.152  -1.207  -1.016  -1.132
357   E        -0.201  -0.254  -0.339  -0.165  -0.231  -0.354  -0.302  -0.381  -0.517
358   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
359   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
360   R        -1.230  -1.196  -1.204  -1.237  -1.188  -1.182  -1.207  -1.160  -1.139
361   H         1.012   1.021   1.043   1.172   1.184   1.209   1.056   1.067   1.094
362   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
363   Y        -0.201  -0.254  -0.339  -0.041  -0.121  -0.262  -0.302  -0.381  -0.517
364   L        -0.201  -0.271  -0.335  -0.474  -0.569  -0.629  -0.302  -0.408  -0.512
365   A         1.012   1.021   1.043   1.013   1.021   1.061   1.056   1.067   1.094
366   M        -1.230  -1.196  -1.204  -1.094  -1.058  -1.047  -1.207  -1.160  -1.139
367   Y         1.012   1.021   1.043   1.118   1.132   1.159   1.056   1.067   1.094
368   H         1.012   1.021   1.043   1.172   1.184   1.209   1.056   1.067   1.094
369   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
370   P        -0.201  -0.271  -0.335  -0.179  -0.293  -0.398  -0.302  -0.408  -0.512
371   S        -1.230  -1.202  -1.207  -1.224  -1.174  -1.189  -1.207  -1.164  -1.143
372   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
373   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
374   P         1.012   1.021   1.043   1.009   1.021   1.057   1.056   1.067   1.094
375   E        -1.977  -1.931  -1.833  -1.854  -1.763  -1.621  -1.659  -1.600  -1.459
376   Y        -1.230  -1.294  -1.224  -1.079  -1.189  -1.076  -1.207  -1.271  -1.162
377   P        -0.201  -0.271  -0.335  -0.174  -0.283  -0.390  -0.302  -0.408  -0.512
378   P        -0.201  -0.106  -0.317  -0.127   0.007  -0.290  -0.302  -0.157  -0.482
379   L        -0.201  -0.271  -0.335  -0.445  -0.534  -0.585  -0.302  -0.408  -0.512
380   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
381   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
382   N         1.012   1.021   1.043   1.095   1.107   1.137   1.056   1.067   1.094
383   L        -0.201  -0.254  -0.339  -0.463  -0.534  -0.616  -0.302  -0.381  -0.517
384   D        -1.977  -1.931  -1.833  -1.910  -1.818  -1.674  -1.659  -1.600  -1.459
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   D         1.012   1.021   1.043   0.989   1.007   1.039   1.056   1.067   1.094
387   E        -1.230  -1.212  -1.205  -1.358  -1.354  -1.323  -1.207  -1.177  -1.140
388   F        -0.201  -0.271  -0.335  -0.041  -0.150  -0.256  -0.302  -0.408  -0.512
389   W        -0.201  -0.271  -0.335   0.149   0.049  -0.067  -0.302  -0.408  -0.512
390   K        -1.230  -1.294  -1.224  -1.136  -1.214  -1.093  -1.207  -1.271  -1.162
391   L        -0.361  -0.299  -0.363  -0.790  -0.683  -0.768  -0.553  -0.451  -0.556
392   D         1.012   1.021   1.043   0.973   0.988   1.023   1.056   1.067   1.094
393   N         1.012   1.021   1.043   1.081   1.090   1.124   1.056   1.067   1.094
394   K        -1.357  -1.318  -1.236  -1.336  -1.233  -1.137  -1.357  -1.299  -1.175
395   I        -1.357  -1.318  -1.236  -1.383  -1.295  -1.180  -1.357  -1.299  -1.175
396   M        -1.357  -1.318  -1.236  -1.323  -1.273  -1.125  -1.357  -1.299  -1.175
397   R        -1.357  -1.318  -1.236  -1.367  -1.301  -1.166  -1.357  -1.299  -1.175
398   P        -1.357  -1.318  -1.236  -1.434  -1.358  -1.228  -1.357  -1.299  -1.175
399   E        -0.361  -0.288  -0.361  -0.398  -0.273  -0.417  -0.553  -0.434  -0.554
400   E        -0.361  -0.420  -0.382  -0.412  -0.494  -0.423  -0.553  -0.646  -0.587
401   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
402   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
403   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
404   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
405   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
406   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
407   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
408   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
409   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
410   E        -1.230  -1.294  -1.224  -1.237  -1.330  -1.212  -1.207  -1.271  -1.162
411   E        -1.230  -1.202  -1.207  -1.261  -1.212  -1.215  -1.207  -1.164  -1.143
412   E        -1.230  -1.185  -1.205  -1.217  -1.137  -1.166  -1.207  -1.146  -1.140
413   V        -1.230  -1.212  -1.205  -1.333  -1.323  -1.330  -1.207  -1.177  -1.140
414   P        -1.230  -1.294  -1.224  -1.208  -1.310  -1.192  -1.207  -1.271  -1.162
415   I        -1.230  -1.202  -1.207  -1.417  -1.352  -1.380  -1.207  -1.164  -1.143
416   E        -1.230  -1.294  -1.224  -1.225  -1.319  -1.197  -1.207  -1.271  -1.162
417   M        -1.977  -1.931  -1.833  -1.966  -1.871  -1.726  -1.659  -1.600  -1.459
418   L         1.012   1.021   1.043   0.680   0.696   0.749   1.056   1.067   1.094
419   K        -0.201  -0.254  -0.339  -0.185  -0.261  -0.394  -0.302  -0.381  -0.517
420   D        -1.977  -1.931  -1.833  -1.952  -1.874  -1.713  -1.659  -1.600  -1.459
421   M        -1.230  -1.294  -1.224  -1.260  -1.411  -1.322  -1.207  -1.271  -1.162
422   L        -0.201  -0.271  -0.335  -0.534  -0.643  -0.724  -0.302  -0.408  -0.512
423   Y        -0.201  -0.271  -0.335  -0.041  -0.148  -0.256  -0.302  -0.408  -0.512
424   D        -1.977  -1.931  -1.833  -1.706  -1.630  -1.483  -1.659  -1.600  -1.459
425   E         1.012   1.021   1.043   0.969   0.990   1.020   1.056   1.067   1.094
426   L        -1.230  -1.185  -1.205  -1.220  -1.115  -1.198  -1.207  -1.146  -1.140
427   M        -0.361  -0.420  -0.382  -0.269  -0.368  -0.324  -0.553  -0.646  -0.587
428   K        -0.361  -0.420  -0.382  -0.450  -0.546  -0.478  -0.553  -0.646  -0.587
429   T        -1.230  -1.196  -1.204  -1.155  -1.107  -1.098  -1.207  -1.160  -1.139
430   M        -1.977  -1.931  -1.833  -1.930  -1.843  -1.692  -1.659  -1.600  -1.459
431   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
432   E        -1.230  -1.082  -1.198  -1.143  -0.908  -1.094  -1.207  -1.016  -1.132
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P14681
Output conservation file - output/P14681
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
