1     M         0.984   1.019   1.059   1.261   1.299   1.338   1.042   1.085   1.148
2     A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     G        -2.026  -1.919  -1.734  -2.178  -2.002  -1.719  -1.769  -1.618  -1.385
6     K        -2.026  -1.867  -1.734  -2.060  -1.777  -1.658  -1.769  -1.575  -1.386
7     K         0.253   0.079  -0.053   0.315   0.112  -0.096   0.249  -0.015  -0.268
8     I        -1.708  -1.512  -1.696  -1.527  -1.252  -1.536  -1.450  -1.239  -1.354
9     A        -0.108  -0.242  -0.144  -0.366  -0.651  -0.477  -0.318  -0.559  -0.431
10    G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
11    V         0.253   0.111  -0.049   0.165  -0.021  -0.255   0.249   0.035  -0.261
12    L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
13    G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
14    A         0.253   0.079  -0.053   0.236   0.027  -0.132   0.249  -0.015  -0.268
15    T         0.984   1.019   1.059   1.105   1.152   1.204   1.042   1.085   1.148
16    G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
17    S         0.253   0.111  -0.049   0.329   0.152  -0.079   0.249   0.035  -0.261
18    V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
19    G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
20    Q         0.984   1.019   1.059   1.160   1.199   1.251   1.042   1.085   1.148
21    R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
22    F         0.984   1.019   1.059   1.145   1.183   1.238   1.042   1.085   1.148
23    I         0.984   1.019   1.059   0.944   1.007   1.066   1.042   1.085   1.148
24    L         0.253   0.111  -0.049   0.247   0.092  -0.143   0.249   0.035  -0.261
25    L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
26    L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
27    A        -0.908  -0.976  -0.825  -1.135  -1.180  -0.902  -1.111  -1.138  -0.934
28    N        -1.454  -1.313  -1.314  -1.415  -1.208  -1.202  -1.450  -1.269  -1.197
29    H         0.984   1.019   1.059   1.225   1.270   1.307   1.042   1.085   1.148
30    P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
31    H        -1.372  -1.267  -1.308  -1.315  -1.171  -1.213  -1.337  -1.179  -1.186
32    F         0.253   0.079  -0.053   0.493   0.244  -0.023   0.249  -0.015  -0.268
33    E        -0.108  -0.242  -0.144  -0.185  -0.427  -0.304  -0.318  -0.559  -0.431
34    L        -0.301  -0.250  -0.147  -0.639  -0.539  -0.383  -0.657  -0.573  -0.435
35    K        -1.918  -1.970  -1.743  -1.842  -1.983  -1.637  -1.677  -1.655  -1.393
36    V        -0.301  -0.259  -0.148  -0.749  -0.698  -0.488  -0.657  -0.589  -0.439
37    L         0.253   0.079  -0.053   0.204  -0.026  -0.270   0.249  -0.015  -0.268
38    G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
39    A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
40    S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
41    S        -1.101  -0.991  -1.280  -0.965  -0.858  -1.283  -0.997  -0.869  -1.158
42    R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
43    S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
44    A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
45    G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
46    K         0.984   1.019   1.059   0.932   0.997   1.056   1.042   1.085   1.148
47    K        -0.445  -0.473  -0.765  -0.330  -0.360  -0.801  -0.431  -0.473  -0.852
48    Y         0.984   1.019   1.059   1.221   1.263   1.304   1.042   1.085   1.148
49    V        -1.372  -1.488  -1.336  -1.518  -1.669  -1.422  -1.337  -1.403  -1.215
50    D         0.253   0.111  -0.049   0.312   0.117  -0.176   0.249   0.035  -0.261
51    A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
52    V        -1.101  -1.106  -1.297  -1.029  -1.038  -1.262  -0.997  -0.991  -1.175
53    N        -2.255  -2.240  -2.064  -1.881  -1.909  -1.689  -1.790  -1.728  -1.501
54    W         0.984   1.019   1.059   1.289   1.330   1.362   1.042   1.085   1.148
55    K         0.984   1.019   1.059   0.932   0.997   1.056   1.042   1.085   1.148
56    Q         0.984   1.019   1.059   1.160   1.199   1.251   1.042   1.085   1.148
57    T        -0.108  -0.242  -0.144  -0.062  -0.338  -0.212  -0.318  -0.559  -0.431
58    D        -1.372  -1.488  -1.336  -1.318  -1.449  -1.255  -1.337  -1.403  -1.215
59    L        -1.708  -1.815  -1.733  -1.641  -1.838  -1.709  -1.450  -1.524  -1.385
60    L        -0.445  -0.743  -0.797  -0.356  -0.728  -0.802  -0.431  -0.812  -0.895
61    P         0.253   0.079  -0.053   0.382   0.150  -0.088   0.249  -0.015  -0.268
62    E        -0.445  -0.743  -0.797  -0.312  -0.742  -0.900  -0.431  -0.812  -0.895
63    S        -2.382  -2.085  -2.053  -2.246  -1.810  -1.771  -1.904  -1.603  -1.494
64    A        -1.101  -1.271  -1.317  -1.011  -1.254  -1.293  -0.997  -1.182  -1.196
65    T        -1.918  -1.827  -1.730  -1.850  -1.754  -1.537  -1.677  -1.553  -1.383
66    D        -1.372  -1.199  -1.316  -1.235  -1.027  -1.138  -1.337  -1.152  -1.197
67    I        -1.708  -1.813  -1.732  -1.496  -1.640  -1.548  -1.450  -1.522  -1.383
68    I        -1.372  -1.267  -1.308  -1.530  -1.365  -1.408  -1.337  -1.178  -1.187
69    V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
70    S        -2.382  -2.183  -2.056  -2.272  -1.968  -1.792  -1.904  -1.691  -1.496
71    E        -0.445  -0.743  -0.797  -0.305  -0.732  -0.883  -0.431  -0.812  -0.895
72    C         0.984   1.019   1.059   1.194   1.238   1.280   1.042   1.085   1.148
73    K        -0.764  -0.793  -0.809  -0.766  -0.777  -0.821  -0.884  -0.881  -0.912
74    S        -0.908  -0.763  -0.813  -1.094  -0.896  -0.921  -1.111  -0.923  -0.921
75    E        -1.101  -1.247  -1.315  -0.913  -1.150  -1.285  -0.997  -1.159  -1.193
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    F        -1.918  -1.598  -1.702  -1.772  -1.320  -1.475  -1.677  -1.333  -1.360
78    F         0.984   1.019   1.059   1.145   1.183   1.238   1.042   1.085   1.148
79    K        -1.581  -1.476  -1.346  -1.823  -1.690  -1.465  -1.564  -1.424  -1.226
80    E        -0.301  -0.244  -0.143  -0.519  -0.415  -0.279  -0.657  -0.562  -0.429
81    C         0.984   1.019   1.059   1.194   1.238   1.280   1.042   1.085   1.148
82    D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
83    I        -0.301  -0.294  -0.150  -0.692  -0.681  -0.420  -0.657  -0.654  -0.442
84    V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
85    F         0.984   1.019   1.059   1.145   1.183   1.238   1.042   1.085   1.148
86    S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
87    G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
88    L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
89    D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
90    A         0.253   0.079  -0.053   0.199  -0.036  -0.233   0.249  -0.015  -0.268
91    D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
92    Y        -1.035  -1.038  -0.859  -0.975  -1.041  -0.800  -1.224  -1.203  -0.974
93    A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
94    G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
95    A        -1.918  -1.737  -1.714  -1.816  -1.548  -1.521  -1.677  -1.455  -1.369
96    I         0.253   0.079  -0.053   0.283   0.050  -0.206   0.249  -0.015  -0.268
97    E         0.984   1.019   1.059   0.983   1.047   1.100   1.042   1.085   1.148
98    K         0.984   1.019   1.059   0.932   0.997   1.056   1.042   1.085   1.148
99    E        -1.372  -1.264  -1.319  -1.378  -1.239  -1.334  -1.337  -1.202  -1.201
100   F         0.984   1.019   1.059   1.145   1.183   1.238   1.042   1.085   1.148
101   M        -1.918  -1.899  -1.730  -1.756  -1.715  -1.448  -1.677  -1.602  -1.383
102   E        -0.764  -0.938  -0.833  -0.720  -0.945  -0.794  -0.884  -1.082  -0.943
103   A         0.253   0.422  -0.029   0.240   0.437  -0.085   0.249   0.484  -0.226
104   G        -0.108  -0.242  -0.144  -0.200  -0.413  -0.254  -0.318  -0.559  -0.431
105   I        -0.108  -0.135  -0.134  -0.296  -0.330  -0.361  -0.318  -0.369  -0.413
106   A        -0.764  -0.705  -0.813  -0.977  -0.948  -1.057  -0.884  -0.826  -0.918
107   I        -0.108  -0.115  -0.133  -0.353  -0.373  -0.401  -0.318  -0.335  -0.411
108   V        -0.908  -0.976  -0.823  -1.140  -1.198  -0.937  -1.111  -1.138  -0.933
109   S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
110   N         0.984   1.019   1.059   1.110   1.152   1.208   1.042   1.085   1.148
111   A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
112   K         0.984   1.019   1.059   0.932   0.997   1.056   1.042   1.085   1.148
113   N         0.984   1.019   1.059   1.110   1.152   1.208   1.042   1.085   1.148
114   Y         0.984   1.019   1.059   1.221   1.263   1.304   1.042   1.085   1.148
115   R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
116   R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
117   E         0.253   0.079  -0.053   0.346   0.131  -0.109   0.249  -0.015  -0.268
118   Q        -1.918  -1.552  -1.707  -1.810  -1.250  -1.515  -1.677  -1.271  -1.364
119   D        -0.764  -0.938  -0.833  -0.748  -1.010  -0.869  -0.884  -1.082  -0.943
120   V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
121   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
122   L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
123   I        -0.108   0.081  -0.081  -0.353  -0.065  -0.310  -0.318  -0.012  -0.317
124   V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
125   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
126   V        -0.908  -0.768  -0.819  -1.024  -0.791  -0.869  -1.111  -0.930  -0.926
127   V        -0.445  -0.271  -0.747  -0.460  -0.248  -0.876  -0.431  -0.200  -0.829
128   N         0.984   1.019   1.059   1.110   1.152   1.208   1.042   1.085   1.148
129   P        -1.101  -1.336  -1.329  -0.861  -1.221  -1.256  -0.997  -1.244  -1.207
130   E        -0.445  -0.743  -0.797  -0.260  -0.654  -0.772  -0.431  -0.812  -0.895
131   H         0.984   1.019   1.059   1.225   1.270   1.307   1.042   1.085   1.148
132   L         0.253   0.390  -0.030   0.224   0.416  -0.174   0.249   0.441  -0.227
133   D         0.253   0.393  -0.030   0.331   0.512  -0.087   0.249   0.445  -0.228
134   I        -1.581  -1.520  -1.345  -1.785  -1.706  -1.392  -1.564  -1.456  -1.225
135   V        -0.764  -0.835  -0.832  -0.914  -1.051  -0.946  -0.884  -0.991  -0.943
136   A        -2.382  -2.316  -2.065  -2.328  -2.219  -1.845  -1.904  -1.782  -1.502
137   Q        -2.718  -2.586  -2.338  -2.222  -1.992  -1.757  -2.017  -1.856  -1.580
138   K        -1.496  -1.360  -1.337  -1.393  -1.185  -1.119  -1.473  -1.307  -1.217
139   L        -0.323  -0.219  -0.140  -0.764  -0.575  -0.447  -0.698  -0.517  -0.424
140   D        -1.603  -1.442  -1.349  -1.837  -1.584  -1.438  -1.568  -1.353  -1.228
141   T        -1.603  -1.429  -1.349  -1.674  -1.417  -1.273  -1.568  -1.338  -1.227
142   A         0.984   1.019   1.059   0.850   0.902   0.985   1.042   1.085   1.148
143   K        -0.908  -0.775  -0.819  -1.032  -0.810  -0.873  -1.111  -0.936  -0.926
144   A        -1.581  -1.407  -1.334  -1.686  -1.404  -1.292  -1.564  -1.347  -1.214
145   Q        -2.382  -2.242  -2.051  -2.241  -2.013  -1.760  -1.904  -1.731  -1.493
146   G        -1.101  -1.234  -1.308  -0.931  -1.151  -1.211  -0.997  -1.148  -1.186
147   K        -0.764  -0.654  -0.803  -0.815  -0.694  -0.863  -0.884  -0.765  -0.907
148   P        -1.496  -1.319  -1.341  -1.570  -1.349  -1.360  -1.473  -1.267  -1.221
149   R        -1.372  -1.475  -1.331  -1.319  -1.447  -1.251  -1.337  -1.388  -1.210
150   P        -1.708  -1.784  -1.726  -1.422  -1.559  -1.497  -1.450  -1.500  -1.379
151   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
152   F        -0.445  -0.555  -0.775  -0.047  -0.193  -0.500  -0.431  -0.570  -0.865
153   I        -0.445  -0.583  -0.777  -0.309  -0.498  -0.789  -0.431  -0.610  -0.868
154   I         0.253   0.079  -0.053   0.283   0.050  -0.206   0.249  -0.015  -0.268
155   C         0.253   0.111  -0.049   0.574   0.393   0.113   0.249   0.035  -0.261
156   I        -0.301  -0.295  -0.149  -0.480  -0.456  -0.222  -0.657  -0.656  -0.439
157   S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
158   N         0.984   1.019   1.059   1.110   1.152   1.208   1.042   1.085   1.148
159   C         0.984   1.019   1.059   1.194   1.238   1.280   1.042   1.085   1.148
160   S         0.253   0.079  -0.053   0.291   0.043  -0.190   0.249  -0.015  -0.268
161   T         0.253   0.079  -0.053   0.445   0.194  -0.077   0.249  -0.015  -0.268
162   A         0.253   0.079  -0.053   0.198  -0.032  -0.235   0.249  -0.015  -0.268
163   G         0.253   0.111  -0.049   0.251   0.066  -0.215   0.249   0.035  -0.261
164   L         0.253   0.111  -0.049   0.204   0.023  -0.263   0.249   0.035  -0.261
165   V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
166   A        -0.445  -0.555  -0.775  -0.460  -0.631  -0.974  -0.431  -0.570  -0.865
167   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
168   L         0.253   0.079  -0.053   0.253   0.056  -0.133   0.249  -0.015  -0.268
169   K         0.253   0.079  -0.053   0.276   0.049  -0.202   0.249  -0.015  -0.268
170   P        -0.301  -0.295  -0.149  -0.553  -0.604  -0.355  -0.657  -0.656  -0.439
171   L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
172   I        -0.764  -0.762  -0.824  -0.868  -0.882  -0.897  -0.884  -0.921  -0.933
173   E        -0.908  -0.976  -0.824  -1.068  -1.154  -0.932  -1.111  -1.138  -0.933
174   K        -0.908  -0.976  -0.824  -1.137  -1.200  -0.941  -1.111  -1.138  -0.933
175   F        -0.108   0.086  -0.086   0.063   0.332   0.060  -0.318  -0.004  -0.326
176   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
177   P         0.253   0.079  -0.053   0.380   0.151  -0.094   0.249  -0.015  -0.268
178   I         0.984   1.019   1.059   0.944   1.007   1.066   1.042   1.085   1.148
179   D        -1.101  -1.005  -1.286  -0.940  -0.840  -1.274  -0.997  -0.883  -1.163
180   A        -1.918  -1.965  -1.738  -1.956  -1.935  -1.615  -1.677  -1.650  -1.389
181   L        -0.764  -0.927  -0.832  -0.919  -1.171  -1.007  -0.884  -1.072  -0.943
182   T        -1.101  -1.336  -1.329  -0.765  -1.125  -1.172  -0.997  -1.244  -1.207
183   T        -0.301  -0.295  -0.149  -0.496  -0.572  -0.326  -0.657  -0.656  -0.439
184   T        -0.108  -0.242  -0.144  -0.106  -0.411  -0.290  -0.318  -0.559  -0.431
185   T         0.253   0.111  -0.049   0.464   0.274  -0.016   0.249   0.035  -0.261
186   L        -0.301  -0.295  -0.149  -0.465  -0.399  -0.166  -0.657  -0.656  -0.439
187   Q         0.984   1.019   1.059   1.160   1.199   1.251   1.042   1.085   1.148
188   A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
189   I        -0.108  -0.174  -0.136  -0.264  -0.397  -0.382  -0.318  -0.437  -0.416
190   S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
191   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
192   A         0.253   0.393  -0.030   0.193   0.370  -0.209   0.249   0.445  -0.228
193   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
194   F        -0.108  -0.242  -0.144   0.063  -0.168  -0.034  -0.318  -0.559  -0.431
195   S         0.984   1.019   1.059   0.962   1.010   1.082   1.042   1.085   1.148
196   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
197   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
198   V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
199   P        -0.301  -0.295  -0.151  -0.497  -0.523  -0.286  -0.657  -0.655  -0.443
200   G        -0.362  -0.255  -0.134  -0.718  -0.520  -0.322  -0.771  -0.583  -0.413
201   I        -0.908  -0.959  -0.824  -0.914  -0.934  -0.758  -1.111  -1.120  -0.932
202   D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
203   I        -0.108  -0.000  -0.111  -0.264  -0.078  -0.325  -0.318  -0.143  -0.370
204   L         0.253   0.079  -0.053   0.224   0.012  -0.215   0.249  -0.015  -0.268
205   D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
206   N         0.984   1.019   1.059   1.110   1.152   1.208   1.042   1.085   1.148
207   I        -0.445  -0.583  -0.777  -0.368  -0.571  -0.931  -0.431  -0.610  -0.868
208   I        -0.362  -0.267  -0.141  -0.795  -0.640  -0.414  -0.771  -0.604  -0.425
209   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
210   Y        -0.108  -0.242  -0.144   0.111  -0.142  -0.026  -0.318  -0.559  -0.431
211   I         0.984   1.019   1.059   0.944   1.007   1.066   1.042   1.085   1.148
212   G        -0.362  -0.293  -0.150  -0.718  -0.599  -0.356  -0.771  -0.651  -0.442
213   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
214   E         0.984   1.019   1.059   0.983   1.047   1.100   1.042   1.085   1.148
215   E         0.984   1.019   1.059   0.983   1.047   1.100   1.042   1.085   1.148
216   D        -0.108  -0.118  -0.131  -0.179  -0.197  -0.257  -0.318  -0.341  -0.407
217   K         0.984   1.019   1.059   0.932   0.997   1.056   1.042   1.085   1.148
218   M        -1.035  -1.033  -0.859  -1.002  -1.050  -0.847  -1.224  -1.197  -0.973
219   E         0.984   1.019   1.059   0.983   1.047   1.100   1.042   1.085   1.148
220   W         0.253   0.079  -0.053   0.669   0.438   0.179   0.249  -0.015  -0.268
221   E         0.984   1.019   1.059   0.983   1.047   1.100   1.042   1.085   1.148
222   T         0.253   0.079  -0.053   0.449   0.202  -0.064   0.249  -0.015  -0.268
223   K        -0.445  -0.743  -0.797  -0.280  -0.653  -0.733  -0.431  -0.812  -0.895
224   K         0.984   1.019   1.059   0.932   0.997   1.056   1.042   1.085   1.148
225   I         0.984   1.019   1.059   0.944   1.007   1.066   1.042   1.085   1.148
226   L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
227   A         0.253   0.401  -0.029   0.251   0.450  -0.178   0.249   0.456  -0.226
228   P        -2.382  -2.067  -2.053  -2.302  -1.829  -1.812  -1.904  -1.593  -1.494
229   L        -0.362  -0.295  -0.151  -0.855  -0.738  -0.476  -0.771  -0.655  -0.442
230   A        -0.908  -0.702  -0.804  -0.977  -0.649  -0.818  -1.111  -0.823  -0.907
231   E        -2.255  -1.982  -2.033  -2.073  -1.747  -1.736  -1.790  -1.516  -1.480
232   D        -0.445  -0.476  -0.764  -0.270  -0.308  -0.727  -0.431  -0.476  -0.852
233   K        -1.918  -1.894  -1.730  -1.948  -1.937  -1.660  -1.677  -1.599  -1.383
234   T        -0.908  -0.830  -0.814  -0.982  -0.864  -0.850  -1.111  -0.983  -0.923
235   H        -2.382  -2.288  -2.061  -2.108  -2.055  -1.669  -1.904  -1.766  -1.500
236   V        -1.372  -1.238  -1.306  -1.212  -0.971  -1.125  -1.337  -1.149  -1.185
237   K        -1.372  -1.046  -1.294  -1.360  -0.860  -1.254  -1.337  -0.937  -1.174
238   L        -1.257  -1.105  -1.315  -1.203  -0.968  -1.278  -1.178  -0.979  -1.193
239   L        -0.362  -0.287  -0.151  -0.773  -0.619  -0.403  -0.771  -0.641  -0.442
240   T        -1.496  -1.491  -1.346  -1.491  -1.506  -1.246  -1.473  -1.431  -1.225
241   P        -1.496  -1.456  -1.338  -1.475  -1.376  -1.210  -1.473  -1.390  -1.217
242   E        -1.918  -1.937  -1.736  -1.849  -1.865  -1.575  -1.677  -1.635  -1.387
243   E        -0.908  -0.974  -0.821  -1.002  -1.041  -0.808  -1.111  -1.135  -0.931
244   I        -1.454  -1.394  -1.322  -1.500  -1.383  -1.200  -1.450  -1.335  -1.203
245   K        -0.445  -0.743  -0.797  -0.339  -0.753  -0.876  -0.431  -0.812  -0.895
246   V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
247   S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
248   A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
249   Q        -0.445  -0.583  -0.777  -0.108  -0.332  -0.665  -0.431  -0.610  -0.868
250   C         0.984   1.019   1.059   1.194   1.238   1.280   1.042   1.085   1.148
251   N         0.984   1.019   1.059   1.110   1.152   1.208   1.042   1.085   1.148
252   R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
253   V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
254   A        -0.301  -0.295  -0.151  -0.618  -0.605  -0.348  -0.657  -0.655  -0.443
255   V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
256   S        -0.908  -0.976  -0.825  -1.111  -1.192  -0.962  -1.111  -1.138  -0.934
257   D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
258   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
259   H         0.984   1.019   1.059   1.225   1.270   1.307   1.042   1.085   1.148
260   T         0.253   0.111  -0.049   0.452   0.261  -0.047   0.249   0.035  -0.261
261   E        -0.445  -0.743  -0.797  -0.256  -0.655  -0.762  -0.431  -0.812  -0.895
262   C         0.984   1.019   1.059   1.194   1.238   1.280   1.042   1.085   1.148
263   I        -0.108  -0.174  -0.136  -0.264  -0.397  -0.382  -0.318  -0.437  -0.416
264   S         0.253   0.300  -0.035   0.291   0.353  -0.157   0.249   0.317  -0.237
265   L        -0.764  -0.786  -0.804  -0.845  -0.868  -0.901  -0.884  -0.871  -0.906
266   R        -0.908  -0.835  -0.815  -0.968  -0.859  -0.825  -1.111  -0.992  -0.924
267   F         0.984   1.019   1.059   1.145   1.183   1.238   1.042   1.085   1.148
268   K        -0.362  -0.267  -0.141  -0.779  -0.615  -0.397  -0.771  -0.604  -0.425
269   N        -0.562  -0.796  -0.822  -0.274  -0.617  -0.705  -0.586  -0.895  -0.927
270   R        -1.101  -1.080  -1.294  -0.751  -0.764  -1.088  -0.997  -0.964  -1.172
271   P        -1.101  -1.067  -1.290  -0.816  -0.783  -1.106  -0.997  -0.951  -1.167
272   A        -1.918  -1.852  -1.725  -2.015  -1.907  -1.720  -1.677  -1.573  -1.379
273   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
274   S         0.253   0.111  -0.049   0.329   0.152  -0.079   0.249   0.035  -0.261
275   V        -1.101  -1.269  -1.316  -1.116  -1.396  -1.460  -0.997  -1.179  -1.195
276   E        -0.301  -0.267  -0.150  -0.519  -0.462  -0.293  -0.657  -0.604  -0.442
277   Q        -0.908  -0.774  -0.813  -0.925  -0.734  -0.757  -1.111  -0.934  -0.921
278   V         0.253   0.438  -0.023   0.153   0.382  -0.240   0.249   0.505  -0.216
279   K         0.253   0.111  -0.049   0.315   0.156  -0.090   0.249   0.035  -0.261
280   T        -1.581  -1.430  -1.347  -1.516  -1.327  -1.189  -1.564  -1.377  -1.226
281   C        -1.581  -1.564  -1.348  -1.555  -1.613  -1.277  -1.564  -1.485  -1.227
282   L         0.253   0.079  -0.053   0.271   0.085  -0.085   0.249  -0.015  -0.268
283   K        -1.708  -1.580  -1.698  -1.392  -1.260  -1.477  -1.450  -1.298  -1.356
284   E        -1.372  -1.486  -1.333  -1.316  -1.454  -1.247  -1.337  -1.400  -1.212
285   Y         0.984   1.019   1.059   1.221   1.263   1.304   1.042   1.085   1.148
286   V         0.253   0.390  -0.030   0.171   0.340  -0.206   0.249   0.441  -0.227
287   C        -0.301  -0.295  -0.149  -0.346  -0.408  -0.182  -0.657  -0.656  -0.439
288   D        -0.764  -0.708  -0.813  -0.800  -0.745  -0.911  -0.884  -0.828  -0.918
289   A        -0.108  -0.157  -0.132  -0.294  -0.382  -0.333  -0.318  -0.408  -0.410
290   Y        -1.581  -1.276  -1.325  -1.455  -0.993  -1.121  -1.564  -1.194  -1.205
291   K         0.984   1.019   1.059   0.932   0.997   1.056   1.042   1.085   1.148
292   L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
293   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
294   C         0.984   1.019   1.059   1.194   1.238   1.280   1.042   1.085   1.148
295   H        -0.764  -0.927  -0.832  -0.478  -0.732  -0.628  -0.884  -1.072  -0.943
296   S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
297   A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
298   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
299   K         0.253   0.079  -0.053   0.297   0.088  -0.145   0.249  -0.015  -0.268
300   Q        -0.445  -0.583  -0.777  -0.107  -0.309  -0.662  -0.431  -0.610  -0.868
301   T        -0.764  -0.938  -0.833  -0.693  -0.995  -0.872  -0.884  -1.082  -0.943
302   I         0.984   1.019   1.059   0.944   1.007   1.066   1.042   1.085   1.148
303   H        -0.445  -0.743  -0.797  -0.011  -0.425  -0.578  -0.431  -0.812  -0.895
304   V         0.253   0.300  -0.035   0.153   0.218  -0.262   0.249   0.317  -0.237
305   L        -0.108  -0.242  -0.144  -0.229  -0.426  -0.261  -0.318  -0.559  -0.431
306   E        -0.301  -0.295  -0.151  -0.519  -0.519  -0.295  -0.657  -0.655  -0.443
307   Q        -0.764  -0.905  -0.824  -0.598  -0.831  -0.766  -0.884  -1.039  -0.934
308   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   P        -1.372  -1.273  -1.305  -1.267  -1.143  -1.206  -1.337  -1.184  -1.184
311   D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
312   R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
313   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
314   Q         0.984   1.019   1.059   1.160   1.199   1.251   1.042   1.085   1.148
315   P         0.984   1.019   1.059   1.023   1.074   1.134   1.042   1.085   1.148
316   R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
317   L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
318   D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
319   R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
320   N        -0.908  -0.756  -0.814  -0.910  -0.726  -0.742  -1.111  -0.923  -0.922
321   R        -0.445  -0.743  -0.797  -0.156  -0.592  -0.729  -0.431  -0.812  -0.895
322   D        -0.445  -0.743  -0.797  -0.255  -0.642  -0.741  -0.431  -0.812  -0.895
323   S        -0.908  -0.933  -0.818  -0.959  -0.956  -0.813  -1.111  -1.075  -0.925
324   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
325   Y         0.984   1.019   1.059   1.221   1.263   1.304   1.042   1.085   1.148
326   G        -0.764  -0.938  -0.833  -0.866  -1.128  -0.961  -0.884  -1.082  -0.943
327   V         0.253   0.300  -0.035   0.150   0.212  -0.272   0.249   0.317  -0.237
328   S         0.984   1.019   1.059   0.947   0.992   1.069   1.042   1.085   1.148
329   V         0.984   1.019   1.059   0.807   0.851   0.948   1.042   1.085   1.148
330   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
331   R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
332   I        -0.362  -0.295  -0.152  -0.795  -0.681  -0.427  -0.771  -0.656  -0.444
333   R         0.984   1.019   1.059   1.106   1.145   1.205   1.042   1.085   1.148
334   E        -0.445  -0.432  -0.756  -0.309  -0.296  -0.818  -0.431  -0.426  -0.841
335   D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
336   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
337   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   P        -1.372  -1.459  -1.336  -1.356  -1.524  -1.367  -1.337  -1.391  -1.216
339   L        -1.035  -0.985  -0.853  -1.402  -1.312  -1.099  -1.224  -1.147  -0.966
340   L        -0.108  -0.242  -0.144  -0.229  -0.426  -0.261  -0.318  -0.559  -0.431
341   D         0.984   1.019   1.059   0.972   1.025   1.090   1.042   1.085   1.148
342   F        -0.108  -0.242  -0.144  -0.025  -0.302  -0.187  -0.318  -0.559  -0.431
343   K         0.984   1.019   1.059   0.932   0.997   1.056   1.042   1.085   1.148
344   M        -0.301  -0.295  -0.149  -0.189  -0.229  -0.018  -0.657  -0.656  -0.439
345   V         0.253   0.300  -0.035   0.189   0.252  -0.168   0.249   0.317  -0.237
346   V        -0.445  -0.743  -0.797  -0.488  -0.937  -1.023  -0.431  -0.812  -0.895
347   L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
348   S         0.253   0.111  -0.049   0.287   0.084  -0.196   0.249   0.035  -0.261
349   H         0.984   1.019   1.059   1.225   1.270   1.307   1.042   1.085   1.148
350   N         0.984   1.019   1.059   1.110   1.152   1.208   1.042   1.085   1.148
351   T         0.984   1.019   1.059   1.105   1.152   1.204   1.042   1.085   1.148
352   I        -0.362  -0.255  -0.134  -0.795  -0.619  -0.403  -0.771  -0.583  -0.413
353   I         0.253   0.111  -0.049   0.291   0.117  -0.176   0.249   0.035  -0.261
354   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
355   A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
356   A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
357   G         0.984   1.019   1.059   0.907   0.966   1.034   1.042   1.085   1.148
358   S        -0.362  -0.295  -0.152  -0.767  -0.661  -0.402  -0.771  -0.655  -0.444
359   G         0.253   0.079  -0.053   0.267   0.043  -0.180   0.249  -0.015  -0.268
360   V         0.253   0.401  -0.029   0.283   0.487  -0.160   0.249   0.456  -0.226
361   L         0.984   1.019   1.059   0.865   0.931   0.998   1.042   1.085   1.148
362   I        -0.108  -0.242  -0.144  -0.165  -0.377  -0.229  -0.318  -0.559  -0.431
363   A         0.984   1.019   1.059   0.840   0.887   0.976   1.042   1.085   1.148
364   E         0.984   1.019   1.059   0.983   1.047   1.100   1.042   1.085   1.148
365   I        -1.101  -1.336  -1.329  -0.972  -1.365  -1.376  -0.997  -1.244  -1.207
366   L        -0.108  -0.242  -0.144  -0.330  -0.591  -0.439  -0.318  -0.559  -0.431
367   L        -1.101  -1.271  -1.317  -1.066  -1.342  -1.441  -0.997  -1.182  -1.196
368   A        -0.764  -0.938  -0.833  -0.887  -1.125  -0.934  -0.884  -1.082  -0.943
369   R         0.253   0.401  -0.029   0.315   0.511  -0.058   0.249   0.456  -0.226
370   N        -0.108  -0.242  -0.144  -0.069  -0.350  -0.231  -0.318  -0.559  -0.431
371   L        -0.764  -0.506  -0.783  -0.925  -0.515  -0.967  -0.884  -0.521  -0.879
372   I         0.253   0.111  -0.049   0.349   0.201  -0.020   0.249   0.035  -0.261
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P13663
Output conservation file - output/P13663
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
