1     M         0.809   0.840   0.878   1.081   1.104   1.139   0.843   0.884   0.938
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     D        -2.170  -2.056  -1.833  -2.362  -2.177  -1.882  -2.038  -1.881  -1.566
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     N        -2.561  -2.527  -2.270  -2.382  -2.422  -2.055  -2.164  -2.084  -1.735
9     E        -1.632  -1.567  -1.281  -1.941  -1.815  -1.387  -1.788  -1.677  -1.298
10    V        -0.041   0.132  -0.397   0.088   0.293  -0.463  -0.034   0.199  -0.592
11    E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
12    K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
13    N        -0.041  -0.340  -0.424   0.132  -0.280  -0.461  -0.034  -0.474  -0.637
14    I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
15    E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
16    I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
17    W         0.809   0.840   0.878   1.152   1.182   1.196   0.843   0.884   0.938
18    K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
19    V        -0.041  -0.340  -0.424   0.034  -0.376  -0.537  -0.034  -0.474  -0.637
20    K        -0.459  -0.592  -0.480  -0.601  -0.809  -0.616  -0.660  -0.886  -0.731
21    K        -0.041  -0.340  -0.424  -0.044  -0.419  -0.543  -0.034  -0.474  -0.637
22    L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
23    V        -0.683  -0.654  -0.483  -0.928  -0.903  -0.640  -1.036  -0.993  -0.736
24    Q        -0.850  -0.536  -1.199  -0.730  -0.347  -1.163  -0.786  -0.393  -1.200
25    S        -1.612  -1.857  -1.825  -1.263  -1.633  -1.573  -1.412  -1.666  -1.558
26    L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
27    E        -0.041  -0.340  -0.424  -0.093  -0.492  -0.630  -0.034  -0.474  -0.637
28    K        -2.709  -2.582  -2.277  -2.528  -2.381  -1.911  -2.289  -2.123  -1.739
29    A        -0.041  -0.340  -0.424   0.141  -0.233  -0.351  -0.034  -0.474  -0.637
30    R        -0.041  -0.340  -0.424   0.270  -0.129  -0.265  -0.034  -0.474  -0.637
31    G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
32    N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
33    G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
34    T         0.809   0.840   0.878   0.879   0.919   0.971   0.843   0.884   0.938
35    S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
36    M         0.809   0.840   0.878   1.081   1.104   1.139   0.843   0.884   0.938
37    I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
38    S        -0.041  -0.340  -0.424   0.096  -0.322  -0.467  -0.034  -0.474  -0.637
39    L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
40    V        -0.683  -0.679  -0.482  -0.943  -0.959  -0.639  -1.036  -1.037  -0.735
41    I        -0.041  -0.009  -0.407   0.118   0.166  -0.359  -0.034   0.011  -0.609
42    P         0.809   0.840   0.878   1.059   1.092   1.120   0.843   0.884   0.938
43    P         0.809   0.840   0.878   1.059   1.092   1.120   0.843   0.884   0.938
44    K        -0.041  -0.340  -0.424  -0.075  -0.476  -0.637  -0.034  -0.474  -0.637
45    G        -1.612  -1.857  -1.825  -1.423  -1.847  -1.809  -1.412  -1.666  -1.558
46    Q         0.809   0.840   0.878   0.958   0.989   1.037   0.843   0.884   0.938
47    I        -0.041   0.134  -0.397   0.071   0.288  -0.475  -0.034   0.200  -0.592
48    P        -0.683  -0.542  -0.469  -0.763  -0.570  -0.450  -1.036  -0.802  -0.712
49    L        -1.927  -1.876  -1.827  -1.858  -1.801  -1.587  -1.788  -1.730  -1.561
50    Y        -2.023  -1.839  -1.814  -1.906  -1.628  -1.623  -1.913  -1.685  -1.549
51    Q        -1.221  -1.340  -1.262  -1.038  -1.302  -1.192  -1.287  -1.436  -1.277
52    K        -0.041  -0.340  -0.424  -0.059  -0.441  -0.587  -0.034  -0.474  -0.637
53    M         0.809   0.840   0.878   1.081   1.104   1.139   0.843   0.884   0.938
54    L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
55    T        -0.459  -0.608  -0.481  -0.434  -0.725  -0.554  -0.660  -0.914  -0.733
56    D        -0.683  -0.559  -0.473  -1.076  -0.857  -0.730  -1.036  -0.830  -0.719
57    E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
58    Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
59    G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
60    T         0.809   0.840   0.878   0.879   0.919   0.971   0.843   0.884   0.938
61    A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
62    S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
63    N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
64    I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
65    K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
66    S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
67    R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
68    V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
69    N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
70    R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
71    L        -0.459  -0.448  -0.466  -0.669  -0.659  -0.648  -0.660  -0.647  -0.708
72    S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
73    V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
74    L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
75    S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
76    A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
77    I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
78    T         0.809   0.840   0.878   0.879   0.919   0.971   0.843   0.884   0.938
79    S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
80    T         0.809   0.840   0.878   0.879   0.919   0.971   0.843   0.884   0.938
81    Q        -0.041  -0.340  -0.424   0.253  -0.162  -0.329  -0.034  -0.474  -0.637
82    Q        -0.041  -0.340  -0.424   0.209  -0.243  -0.466  -0.034  -0.474  -0.637
83    K        -0.683  -0.679  -0.482  -0.951  -0.926  -0.600  -1.036  -1.037  -0.735
84    L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
85    K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
86    L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
87    Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
88    N        -0.041   0.097  -0.399   0.140   0.308  -0.393  -0.034   0.153  -0.596
89    T        -2.023  -1.803  -1.812  -2.060  -1.773  -1.698  -1.913  -1.646  -1.548
90    L        -1.221  -0.929  -1.225  -1.313  -0.869  -1.349  -1.287  -0.892  -1.231
91    P         0.809   0.840   0.878   1.059   1.092   1.120   0.843   0.884   0.938
92    K        -2.561  -2.483  -2.268  -2.234  -2.160  -1.901  -2.164  -2.044  -1.733
93    N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
94    G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
95    L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
96    V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
97    L        -1.536  -1.520  -1.280  -1.870  -1.844  -1.454  -1.662  -1.625  -1.297
98    Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
99    C         0.809   0.840   0.878   1.126   1.156   1.175   0.843   0.884   0.938
100   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
101   D        -0.459  -0.608  -0.481  -0.601  -0.891  -0.731  -0.660  -0.914  -0.733
102   I        -1.389  -1.202  -1.250  -1.474  -1.224  -1.188  -1.537  -1.291  -1.263
103   I        -0.459  -0.375  -0.459  -0.581  -0.449  -0.679  -0.660  -0.529  -0.696
104   T        -0.041  -0.340  -0.424   0.193  -0.192  -0.330  -0.034  -0.474  -0.637
105   E        -1.927  -1.790  -1.815  -2.002  -1.778  -1.814  -1.788  -1.586  -1.549
106   D        -1.389  -1.490  -1.259  -1.674  -1.786  -1.429  -1.537  -1.587  -1.274
107   G        -0.041  -0.340  -0.424   0.027  -0.383  -0.525  -0.034  -0.474  -0.637
108   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
109   E        -0.041  -0.340  -0.424  -0.081  -0.472  -0.596  -0.034  -0.474  -0.637
110   K        -0.459  -0.608  -0.481  -0.601  -0.835  -0.617  -0.660  -0.914  -0.733
111   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
112   V        -1.389  -1.329  -1.257  -1.607  -1.547  -1.313  -1.537  -1.440  -1.271
113   T        -1.389  -1.238  -1.246  -1.407  -1.168  -1.192  -1.537  -1.303  -1.258
114   F        -0.683  -0.501  -0.455  -0.862  -0.560  -0.523  -1.036  -0.733  -0.689
115   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
116   I        -0.683  -0.501  -0.455  -0.834  -0.520  -0.507  -1.036  -0.733  -0.689
117   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
118   P         0.809   0.840   0.878   1.059   1.092   1.120   0.843   0.884   0.938
119   Y        -0.683  -0.501  -0.455  -0.749  -0.459  -0.428  -1.036  -0.733  -0.689
120   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
121   P         0.809   0.840   0.878   1.059   1.092   1.120   0.843   0.884   0.938
122   I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
123   N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
124   T         0.809   0.840   0.878   0.879   0.919   0.971   0.843   0.884   0.938
125   S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
126   L        -0.041  -0.340  -0.424  -0.116  -0.499  -0.593  -0.034  -0.474  -0.637
127   Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
128   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
129   C         0.809   0.840   0.878   1.126   1.156   1.175   0.843   0.884   0.938
130   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
131   N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
132   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
133   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
134   H         0.809   0.840   0.878   1.111   1.138   1.163   0.843   0.884   0.938
135   T        -0.459  -0.241  -0.427  -0.453  -0.128  -0.477  -0.660  -0.322  -0.643
136   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
137   V        -0.683  -0.501  -0.455  -0.914  -0.605  -0.573  -1.036  -0.733  -0.689
138   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
139   S        -1.221  -1.197  -1.256  -1.167  -1.243  -1.246  -1.287  -1.307  -1.270
140   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
141   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
142   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
143   Q        -0.850  -0.736  -1.210  -0.788  -0.647  -1.268  -0.786  -0.640  -1.213
144   A        -1.632  -1.407  -1.261  -1.794  -1.469  -1.251  -1.788  -1.488  -1.274
145   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
146   D        -1.221  -1.311  -1.262  -1.163  -1.311  -1.222  -1.287  -1.412  -1.277
147   K        -0.683  -0.654  -0.482  -0.951  -0.906  -0.617  -1.036  -0.993  -0.735
148   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
149   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
150   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
151   I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
152   V        -0.683  -0.564  -0.471  -0.943  -0.748  -0.623  -1.036  -0.838  -0.717
153   M         0.809   0.840   0.878   1.081   1.104   1.139   0.843   0.884   0.938
154   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
155   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
156   Q        -1.389  -1.470  -1.258  -1.298  -1.352  -1.053  -1.537  -1.560  -1.272
157   G        -0.041  -0.340  -0.424   0.042  -0.357  -0.479  -0.034  -0.474  -0.637
158   T        -0.459  -0.547  -0.477  -0.471  -0.638  -0.553  -0.660  -0.811  -0.727
159   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
160   F        -0.041  -0.340  -0.424   0.181  -0.211  -0.377  -0.034  -0.474  -0.637
161   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
162   S        -2.561  -2.410  -2.266  -2.481  -2.299  -2.095  -2.164  -1.990  -1.731
163   V        -0.754  -0.677  -0.484  -1.237  -1.109  -0.775  -1.161  -1.033  -0.739
164   S        -1.612  -1.223  -1.778  -1.224  -0.782  -1.444  -1.412  -0.964  -1.514
165   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
166   N        -0.041  -0.340  -0.424   0.131  -0.286  -0.465  -0.034  -0.474  -0.637
167   T        -0.041  -0.340  -0.424   0.155  -0.263  -0.444  -0.034  -0.474  -0.637
168   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
169   T        -1.927  -1.692  -1.811  -1.961  -1.634  -1.779  -1.788  -1.498  -1.546
170   V        -0.041  -0.064  -0.409   0.034   0.010  -0.511  -0.034  -0.064  -0.612
171   L        -0.041  -0.064  -0.409  -0.146  -0.166  -0.659  -0.034  -0.064  -0.612
172   H        -0.041  -0.340  -0.424   0.405  -0.016  -0.219  -0.034  -0.474  -0.637
173   K        -0.041  -0.340  -0.424  -0.044  -0.419  -0.543  -0.034  -0.474  -0.637
174   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
175   T        -0.459  -0.375  -0.459  -0.436  -0.324  -0.515  -0.660  -0.529  -0.696
176   V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
177   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
178   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
179   P         0.809   0.840   0.878   1.059   1.092   1.120   0.843   0.884   0.938
180   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
181   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
182   H         0.809   0.840   0.878   1.111   1.138   1.163   0.843   0.884   0.938
183   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
184   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
185   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
186   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
187   Q         0.809   0.840   0.878   0.958   0.989   1.037   0.843   0.884   0.938
188   S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
189   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
190   L        -0.683  -0.496  -0.461  -1.121  -0.809  -0.747  -1.036  -0.725  -0.700
191   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
192   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
193   A        -0.683  -0.543  -0.467  -0.887  -0.666  -0.570  -1.036  -0.803  -0.709
194   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
195   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
196   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
197   E        -0.041  -0.340  -0.424  -0.098  -0.498  -0.647  -0.034  -0.474  -0.637
198   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
199   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
200   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
201   H         0.809   0.840   0.878   1.111   1.138   1.163   0.843   0.884   0.938
202   N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
203   Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
204   V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
205   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
206   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
207   V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
208   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
209   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
210   V        -0.850  -1.154  -1.240  -0.728  -1.195  -1.398  -0.786  -1.168  -1.250
211   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
212   V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
213   Q         0.809   0.840   0.878   0.958   0.989   1.037   0.843   0.884   0.938
214   N        -0.850  -1.154  -1.240  -0.482  -0.866  -0.959  -0.786  -1.168  -1.250
215   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
216   I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
217   T        -0.041   0.134  -0.397   0.154   0.357  -0.399  -0.034   0.200  -0.592
218   N        -1.221  -1.295  -1.243  -1.141  -1.242  -1.230  -1.287  -1.337  -1.253
219   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
220   K        -0.041  -0.064  -0.409  -0.044  -0.049  -0.521  -0.034  -0.064  -0.612
221   V        -0.459  -0.608  -0.481  -0.469  -0.702  -0.493  -0.660  -0.914  -0.733
222   N        -0.041   0.134  -0.397   0.140   0.348  -0.389  -0.034   0.200  -0.592
223   V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
224   K        -1.221  -1.311  -1.262  -1.311  -1.469  -1.340  -1.287  -1.412  -1.277
225   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
226   L        -0.041  -0.340  -0.424  -0.139  -0.541  -0.664  -0.034  -0.474  -0.637
227   I        -0.459  -0.608  -0.481  -0.525  -0.812  -0.636  -0.660  -0.914  -0.733
228   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
229   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
230   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
231   S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
232   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
233   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
234   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
235   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
236   T        -0.459  -0.369  -0.459  -0.422  -0.296  -0.493  -0.660  -0.520  -0.696
237   D        -0.754  -0.666  -0.482  -1.197  -1.045  -0.743  -1.161  -1.014  -0.735
238   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
239   A        -2.170  -2.168  -1.839  -2.183  -2.207  -1.729  -2.038  -1.972  -1.571
240   K        -1.612  -1.857  -1.825  -1.460  -1.797  -1.755  -1.412  -1.666  -1.558
241   S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
242   E        -0.683  -0.501  -0.455  -1.027  -0.677  -0.672  -1.036  -0.733  -0.689
243   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
244   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
245   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
246   P        -1.632  -1.509  -1.277  -1.582  -1.410  -1.082  -1.788  -1.609  -1.293
247   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
248   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
249   A        -1.221  -1.022  -1.226  -0.981  -0.693  -1.003  -1.287  -0.998  -1.232
250   C        -1.612  -1.753  -1.815  -1.244  -1.516  -1.535  -1.412  -1.569  -1.549
251   K        -0.041  -0.340  -0.424  -0.044  -0.419  -0.543  -0.034  -0.474  -0.637
252   V        -0.459  -0.559  -0.478  -0.553  -0.739  -0.635  -0.660  -0.830  -0.729
253   I        -0.683  -0.574  -0.474  -0.928  -0.745  -0.623  -1.036  -0.855  -0.722
254   S        -0.850  -0.536  -1.199  -0.755  -0.364  -1.218  -0.786  -0.393  -1.200
255   I        -1.221  -1.340  -1.262  -1.169  -1.380  -1.266  -1.287  -1.436  -1.277
256   V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
257   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
258   V        -0.683  -0.496  -0.461  -0.943  -0.629  -0.605  -1.036  -0.725  -0.700
259   S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
260   Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
261   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
262   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
263   E        -0.041  -0.340  -0.424  -0.098  -0.498  -0.647  -0.034  -0.474  -0.637
264   N        -0.041  -0.340  -0.424   0.132  -0.280  -0.461  -0.034  -0.474  -0.637
265   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
266   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
267   N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
268   Q         0.809   0.840   0.878   0.958   0.989   1.037   0.843   0.884   0.938
269   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
270   I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
271   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
272   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
273   S        -0.041  -0.340  -0.424   0.087  -0.339  -0.493  -0.034  -0.474  -0.637
274   A        -0.041  -0.064  -0.409   0.095   0.063  -0.464  -0.034  -0.064  -0.612
275   E        -0.459  -0.542  -0.478  -0.689  -0.828  -0.738  -0.660  -0.802  -0.728
276   A        -0.683  -0.501  -0.455  -0.830  -0.528  -0.503  -1.036  -0.733  -0.689
277   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
278   A        -1.221  -1.340  -1.262  -1.182  -1.427  -1.300  -1.287  -1.436  -1.277
279   N         0.809   0.840   0.878   0.855   0.902   0.952   0.843   0.884   0.938
280   V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
281   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
282   Y        -0.459  -0.547  -0.477  -0.382  -0.536  -0.465  -0.660  -0.811  -0.727
283   V        -0.459  -0.394  -0.463  -0.553  -0.461  -0.608  -0.660  -0.559  -0.703
284   Q         0.809   0.840   0.878   0.958   0.989   1.037   0.843   0.884   0.938
285   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
286   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
287   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
288   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
289   L        -0.683  -0.677  -0.483  -1.097  -1.085  -0.743  -1.036  -1.034  -0.738
290   E        -3.099  -2.951  -2.634  -2.920  -2.687  -2.284  -2.414  -2.241  -1.851
291   A        -2.709  -2.659  -2.278  -2.640  -2.541  -2.043  -2.289  -2.171  -1.741
292   Y        -0.041  -0.340  -0.424   0.250  -0.159  -0.354  -0.034  -0.474  -0.637
293   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
294   D        -0.459  -0.369  -0.459  -0.601  -0.443  -0.681  -0.660  -0.520  -0.696
295   E        -0.041   0.097  -0.399  -0.069   0.102  -0.523  -0.034   0.153  -0.596
296   I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
297   S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
298   Q        -0.850  -1.108  -1.237  -0.474  -0.908  -1.118  -0.786  -1.116  -1.246
299   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
300   T        -0.459  -0.592  -0.480  -0.436  -0.703  -0.557  -0.660  -0.886  -0.731
301   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
302   K        -0.041  -0.064  -0.409  -0.044  -0.049  -0.521  -0.034  -0.064  -0.612
303   F        -1.221  -1.320  -1.256  -1.061  -1.232  -1.165  -1.287  -1.406  -1.271
304   C         0.809   0.840   0.878   1.126   1.156   1.175   0.843   0.884   0.938
305   Y        -0.041  -0.340  -0.424   0.250  -0.159  -0.354  -0.034  -0.474  -0.637
306   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
307   I        -0.850  -1.108  -1.237  -0.619  -1.001  -1.196  -0.786  -1.116  -1.246
308   D        -1.389  -1.490  -1.259  -1.671  -1.777  -1.423  -1.537  -1.587  -1.274
309   D        -0.041  -0.009  -0.407   0.017   0.083  -0.574  -0.034   0.011  -0.609
310   T         0.809   0.840   0.878   0.879   0.919   0.971   0.843   0.884   0.938
311   L        -0.041  -0.340  -0.424  -0.097  -0.463  -0.535  -0.034  -0.474  -0.637
312   K        -0.041  -0.340  -0.424  -0.059  -0.441  -0.587  -0.034  -0.474  -0.637
313   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
314   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
315   D        -0.850  -1.154  -1.240  -0.677  -1.082  -1.279  -0.786  -1.168  -1.250
316   L        -0.041  -0.340  -0.424  -0.164  -0.591  -0.743  -0.034  -0.474  -0.637
317   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
318   A        -0.041   0.145  -0.397   0.095   0.311  -0.443  -0.034   0.215  -0.592
319   V        -0.683  -0.543  -0.467  -0.770  -0.574  -0.445  -1.036  -0.803  -0.709
320   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
321   K        -1.632  -1.416  -1.271  -1.880  -1.494  -1.328  -1.788  -1.495  -1.286
322   L        -1.221  -1.023  -1.229  -1.406  -1.103  -1.396  -1.287  -0.999  -1.237
323   I        -0.041  -0.340  -0.424   0.047  -0.390  -0.601  -0.034  -0.474  -0.637
324   V        -0.041  -0.340  -0.424   0.082  -0.287  -0.393  -0.034  -0.474  -0.637
325   F        -0.683  -0.543  -0.467  -0.749  -0.529  -0.448  -1.036  -0.803  -0.709
326   E        -0.041  -0.340  -0.424  -0.090  -0.490  -0.623  -0.034  -0.474  -0.637
327   N        -0.041  -0.340  -0.424   0.125  -0.287  -0.484  -0.034  -0.474  -0.637
328   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
329   E        -1.536  -1.454  -1.269  -1.802  -1.691  -1.393  -1.662  -1.553  -1.285
330   T        -1.927  -2.056  -1.831  -1.712  -1.873  -1.598  -1.788  -1.868  -1.564
331   I        -0.850  -0.865  -1.221  -0.604  -0.620  -1.136  -0.786  -0.792  -1.226
332   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
333   Y        -0.850  -0.865  -1.221  -0.376  -0.397  -0.872  -0.786  -0.792  -1.226
334   T        -1.221  -1.405  -1.258  -1.166  -1.487  -1.329  -1.287  -1.475  -1.272
335   F        -1.389  -1.257  -1.254  -1.590  -1.416  -1.289  -1.537  -1.377  -1.268
336   K        -0.041   0.097  -0.399  -0.044   0.138  -0.506  -0.034   0.153  -0.596
337   D        -0.459  -0.592  -0.480  -0.529  -0.749  -0.603  -0.660  -0.886  -0.731
338   A        -1.927  -1.639  -1.802  -1.812  -1.410  -1.655  -1.788  -1.436  -1.536
339   E        -0.850  -0.865  -1.221  -0.806  -0.813  -1.327  -0.786  -0.792  -1.226
340   D        -0.683  -0.501  -0.455  -0.976  -0.665  -0.621  -1.036  -0.733  -0.689
341   N        -1.927  -1.775  -1.812  -1.894  -1.662  -1.801  -1.788  -1.588  -1.547
342   E        -0.041  -0.340  -0.424  -0.054  -0.419  -0.513  -0.034  -0.474  -0.637
343   V        -0.041  -0.009  -0.407   0.045   0.088  -0.476  -0.034   0.011  -0.609
344   I        -0.850  -0.572  -1.200  -0.681  -0.326  -1.284  -0.786  -0.437  -1.200
345   K        -3.099  -2.997  -2.641  -2.995  -2.866  -2.368  -2.414  -2.268  -1.855
346   F        -1.389  -1.470  -1.258  -1.168  -1.248  -0.999  -1.537  -1.560  -1.272
347   A        -2.561  -2.592  -2.274  -2.331  -2.327  -1.924  -2.164  -2.122  -1.738
348   E        -2.170  -2.039  -1.835  -2.313  -2.086  -1.811  -2.038  -1.863  -1.567
349   P        -0.683  -0.679  -0.482  -0.752  -0.842  -0.554  -1.036  -1.037  -0.735
350   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
351   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
352   E        -1.612  -1.317  -1.785  -1.559  -1.164  -1.864  -1.412  -1.069  -1.521
353   A        -2.709  -2.467  -2.273  -2.699  -2.280  -2.083  -2.289  -2.022  -1.737
354   K        -2.561  -2.533  -2.276  -2.282  -2.316  -1.979  -2.164  -2.080  -1.739
355   D        -1.612  -1.857  -1.825  -1.393  -1.798  -1.778  -1.412  -1.666  -1.558
356   K        -0.850  -0.865  -1.221  -0.786  -0.788  -1.323  -0.786  -0.792  -1.226
357   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
358   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
359   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
360   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
361   S        -0.850  -0.865  -1.221  -0.665  -0.700  -1.298  -0.786  -0.792  -1.226
362   F        -1.927  -1.862  -1.818  -1.573  -1.565  -1.457  -1.788  -1.714  -1.553
363   A        -3.099  -2.793  -2.631  -2.851  -2.529  -2.187  -2.414  -2.119  -1.849
364   I        -1.927  -1.741  -1.812  -1.976  -1.717  -1.736  -1.788  -1.559  -1.547
365   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
366   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
367   A        -2.709  -2.597  -2.278  -2.820  -2.655  -2.178  -2.289  -2.131  -1.740
368   T         0.809   0.840   0.878   0.886   0.926   0.977   0.843   0.884   0.938
369   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
370   Q        -2.170  -2.048  -1.829  -2.034  -1.900  -1.594  -2.038  -1.873  -1.563
371   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
372   M        -0.041  -0.009  -0.407   0.326   0.346  -0.356  -0.034   0.011  -0.609
373   D        -0.459  -0.273  -0.438  -0.689  -0.396  -0.670  -0.660  -0.370  -0.660
374   V        -1.927  -1.736  -1.814  -1.955  -1.799  -1.814  -1.788  -1.606  -1.550
375   V         0.809   0.840   0.878   0.760   0.805   0.873   0.843   0.884   0.938
376   S        -1.927  -1.627  -1.802  -1.884  -1.441  -1.724  -1.788  -1.424  -1.536
377   E        -0.850  -1.154  -1.240  -0.781  -1.209  -1.290  -0.786  -1.168  -1.250
378   E        -1.927  -1.983  -1.824  -1.850  -1.888  -1.633  -1.788  -1.796  -1.557
379   P        -1.389  -1.498  -1.262  -1.325  -1.536  -1.224  -1.537  -1.599  -1.277
380   L        -0.683  -0.564  -0.471  -1.052  -0.865  -0.694  -1.036  -0.838  -0.717
381   I        -1.389  -1.470  -1.258  -1.676  -1.760  -1.411  -1.537  -1.560  -1.272
382   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
383   W         0.809   0.840   0.878   1.152   1.182   1.196   0.843   0.884   0.938
384   L        -0.041  -0.064  -0.409  -0.139  -0.157  -0.640  -0.034  -0.064  -0.612
385   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
386   A        -0.041   0.132  -0.397  -0.090   0.126  -0.578  -0.034   0.199  -0.592
387   N        -0.683  -0.679  -0.482  -0.697  -0.682  -0.391  -1.036  -1.037  -0.735
388   Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
389   K         0.809   0.840   0.878   0.659   0.724   0.790   0.843   0.884   0.938
390   N        -0.683  -0.679  -0.482  -0.878  -0.903  -0.607  -1.036  -1.037  -0.735
391   F        -0.683  -0.659  -0.484  -0.749  -0.727  -0.474  -1.036  -1.002  -0.738
392   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
393   A         0.809   0.840   0.878   0.820   0.860   0.922   0.843   0.884   0.938
394   T        -2.561  -2.276  -2.255  -2.333  -1.951  -1.956  -2.164  -1.870  -1.724
395   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
396   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
397   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
398   I        -0.683  -0.501  -0.455  -0.943  -0.638  -0.593  -1.036  -0.733  -0.689
399   T        -0.459  -0.608  -0.481  -0.436  -0.735  -0.559  -0.660  -0.914  -0.733
400   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
401   K        -0.754  -0.633  -0.474  -1.038  -0.800  -0.574  -1.161  -0.956  -0.721
402   S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
403   S        -1.221  -1.309  -1.255  -1.110  -1.272  -1.163  -1.287  -1.390  -1.269
404   E         0.809   0.840   0.878   0.633   0.687   0.768   0.843   0.884   0.938
405   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
406   A        -1.612  -1.741  -1.814  -1.257  -1.455  -1.561  -1.412  -1.558  -1.548
407   Q         0.809   0.840   0.878   0.958   0.989   1.037   0.843   0.884   0.938
408   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
409   V        -0.041   0.134  -0.397   0.082   0.278  -0.357  -0.034   0.200  -0.592
410   T        -1.632  -1.559  -1.279  -1.741  -1.693  -1.277  -1.788  -1.667  -1.296
411   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
412   F         0.809   0.840   0.878   0.884   0.930   0.975   0.843   0.884   0.938
413   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
414   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
415   I         0.809   0.840   0.878   0.803   0.854   0.909   0.843   0.884   0.938
416   G         0.809   0.840   0.878   0.745   0.784   0.861   0.843   0.884   0.938
417   A        -0.041  -0.064  -0.409   0.086   0.054  -0.491  -0.034  -0.064  -0.612
418   M        -2.170  -2.156  -1.836  -2.240  -2.246  -1.733  -2.038  -1.959  -1.568
419   L        -0.041  -0.340  -0.424  -0.097  -0.463  -0.535  -0.034  -0.474  -0.637
420   R         0.809   0.840   0.878   0.953   0.974   1.032   0.843   0.884   0.938
421   Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
422   K        -0.041  -0.340  -0.424  -0.044  -0.414  -0.541  -0.034  -0.474  -0.637
423   V        -0.041  -0.340  -0.424   0.004  -0.439  -0.633  -0.034  -0.474  -0.637
424   N        -0.041  -0.340  -0.424   0.125  -0.287  -0.484  -0.034  -0.474  -0.637
425   F        -0.041  -0.340  -0.424   0.128  -0.315  -0.540  -0.034  -0.474  -0.637
426   E        -0.041  -0.340  -0.424  -0.092  -0.496  -0.627  -0.034  -0.474  -0.637
427   Q        -0.041  -0.340  -0.424   0.271  -0.125  -0.274  -0.034  -0.474  -0.637
428   L         0.809   0.840   0.878   0.587   0.637   0.730   0.843   0.884   0.938
429   V        -2.023  -2.027  -1.829  -1.976  -2.004  -1.646  -1.913  -1.864  -1.562
430   D        -1.221  -1.382  -1.256  -1.238  -1.410  -1.281  -1.287  -1.446  -1.270
431   E        -0.850  -0.768  -1.212  -0.823  -0.712  -1.354  -0.786  -0.677  -1.215
432   S         0.809   0.840   0.878   0.811   0.841   0.915   0.843   0.884   0.938
433   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
434   E        -0.754  -0.625  -0.469  -1.197  -0.928  -0.704  -1.161  -0.944  -0.714
435   D        -0.041  -0.340  -0.424   0.017  -0.396  -0.607  -0.034  -0.474  -0.637
436   E        -0.041  -0.340  -0.424  -0.081  -0.469  -0.593  -0.034  -0.474  -0.637
437   Y         0.809   0.840   0.878   0.965   1.006   1.042   0.843   0.884   0.938
438   Y        -0.041  -0.340  -0.424   0.240  -0.184  -0.385  -0.034  -0.474  -0.637
439   D         0.809   0.840   0.878   0.767   0.834   0.879   0.843   0.884   0.938
440   E        -1.221  -1.319  -1.246  -1.287  -1.397  -1.361  -1.287  -1.366  -1.257
441   D        -0.207  -0.067  -0.431  -0.170   0.035  -0.523  -0.271  -0.068  -0.649
442   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
443   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
444   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
445   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
446   D         0.809   0.840   0.878   0.756   0.804   0.869   0.843   0.884   0.938
447   Y        -1.334  -1.278  -1.274  -1.250  -1.192  -1.326  -1.402  -1.313  -1.290
448   D        -0.320  -0.266  -0.463  -0.335  -0.261  -0.595  -0.440  -0.360  -0.703
449   F         0.809   0.840   0.878   0.887   0.929   0.978   0.843   0.884   0.938
450   I        -0.320  -0.293  -0.464  -0.356  -0.327  -0.696  -0.440  -0.401  -0.704
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P12385
Output conservation file - output/P12385
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
