1     M         2.091   2.096   2.141   2.456   2.465   2.545   2.371   2.377   2.451
2     -        -0.289  -0.278  -0.282  -0.496  -0.467  -0.497  -0.390  -0.376  -0.377
3     -         2.091   2.096   2.141   2.096   2.103   2.182   2.371   2.377   2.451
4     -        -0.423  -0.420  -0.379  -0.480  -0.472  -0.410  -0.574  -0.569  -0.509
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -0.423  -0.420  -0.379  -0.279  -0.279  -0.208  -0.574  -0.569  -0.509
8     -         0.634   0.607   0.626   0.374   0.320   0.340   0.408   0.356   0.375
9     -         2.091   2.096   2.141   2.285   2.294   2.372   2.371   2.377   2.451
10    -        -0.423  -0.420  -0.379  -0.480  -0.488  -0.410  -0.574  -0.569  -0.509
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -         0.634   0.607   0.626   0.781   0.734   0.765   0.408   0.356   0.375
14    -        -0.423  -0.420  -0.379  -0.480  -0.490  -0.410  -0.574  -0.569  -0.509
15    -         0.634   0.607   0.626   0.781   0.734   0.765   0.408   0.356   0.375
16    -        -0.423  -0.420  -0.379  -0.553  -0.532  -0.482  -0.574  -0.569  -0.509
17    -         0.634   0.607   0.626   0.419   0.372   0.405   0.408   0.356   0.375
18    -         0.634   0.607   0.626   0.551   0.505   0.536   0.408   0.356   0.375
19    -         0.634   0.642   0.645   0.519   0.531   0.542   0.408   0.421   0.410
20    -         0.634   0.607   0.626   0.804   0.748   0.768   0.408   0.356   0.375
21    -         0.634   0.607   0.626   0.317   0.263   0.287   0.408   0.356   0.375
22    -         0.634   0.607   0.626   0.568   0.532   0.571   0.408   0.356   0.375
23    -         0.634   0.607   0.626   0.419   0.372   0.405   0.408   0.356   0.375
24    -         0.634   0.607   0.626   0.315   0.276   0.308   0.408   0.356   0.375
25    -         0.634   0.607   0.626   0.470   0.424   0.462   0.408   0.356   0.375
26    -        -0.423  -0.420  -0.379  -0.965  -0.959  -0.897  -0.574  -0.569  -0.509
27    -         0.634   0.607   0.626   0.414   0.366   0.399   0.408   0.356   0.375
28    -        -0.423  -0.420  -0.379  -0.643  -0.641  -0.574  -0.574  -0.569  -0.509
29    -        -0.423  -0.420  -0.379  -0.593  -0.576  -0.523  -0.574  -0.569  -0.509
30    -         0.634   0.607   0.626   0.175   0.125   0.147   0.408   0.356   0.375
31    -        -0.423  -0.420  -0.379  -0.744  -0.734  -0.675  -0.574  -0.569  -0.509
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -         2.091   2.096   2.141   2.238   2.245   2.325   2.371   2.377   2.451
45    -        -0.423  -0.420  -0.379  -0.407  -0.402  -0.336  -0.574  -0.569  -0.509
46    -        -0.423  -0.420  -0.379  -0.593  -0.573  -0.523  -0.574  -0.569  -0.509
47    -         0.634   0.642   0.645   0.435   0.448   0.450   0.408   0.421   0.410
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
50    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
51    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
52    -         0.634   0.607   0.626   0.175   0.125   0.147   0.408   0.356   0.375
53    -        -0.423  -0.420  -0.379  -0.382  -0.389  -0.310  -0.574  -0.569  -0.509
54    V         0.804   0.831   0.740   0.902   0.948   0.788   0.714   0.761   0.587
55    A         0.804   0.778   0.750   0.898   0.847   0.782   0.714   0.667   0.605
56    T        -0.289  -0.262  -0.307  -0.404  -0.364  -0.428  -0.390  -0.352  -0.412
57    I        -1.082  -1.080  -1.039  -1.124  -1.115  -1.057  -0.942  -0.939  -0.879
58    M        -1.082  -1.080  -1.039  -0.962  -0.941  -0.895  -0.942  -0.939  -0.879
59    Q        -1.082  -1.080  -1.039  -0.735  -0.736  -0.666  -0.942  -0.939  -0.879
60    T         2.091   2.096   2.141   1.998   2.004   2.083   2.371   2.377   2.451
61    T         0.634   0.656   0.640   0.473   0.508   0.486   0.408   0.447   0.401
62    T        -0.423  -0.418  -0.379  -0.760  -0.746  -0.691  -0.574  -0.566  -0.509
63    T        -0.423  -0.418  -0.379  -0.549  -0.531  -0.479  -0.574  -0.566  -0.509
64    V        -0.423  -0.418  -0.379  -0.621  -0.628  -0.551  -0.574  -0.566  -0.509
65    L        -0.423  -0.418  -0.379  -0.796  -0.799  -0.728  -0.574  -0.566  -0.509
66    T         0.634   0.656   0.640   0.447   0.480   0.457   0.408   0.447   0.401
67    T        -0.423  -0.418  -0.379  -0.659  -0.644  -0.590  -0.574  -0.566  -0.509
68    V         0.634   0.656   0.640   0.569   0.608   0.561   0.408   0.447   0.401
69    A         0.634   0.594   0.623   0.625   0.542   0.581   0.408   0.331   0.369
70    A        -0.423  -0.418  -0.379  -0.589  -0.587  -0.520  -0.574  -0.566  -0.509
71    M        -0.423  -0.418  -0.379  -0.326  -0.323  -0.254  -0.574  -0.566  -0.509
72    S        -0.289  -0.296  -0.287  -0.651  -0.668  -0.647  -0.390  -0.400  -0.384
73    T        -0.289  -0.296  -0.287  -0.578  -0.589  -0.589  -0.390  -0.400  -0.384
74    T         0.804   0.778   0.750   0.747   0.706   0.673   0.714   0.667   0.605
75    L        -0.289  -0.296  -0.287  -0.566  -0.574  -0.574  -0.390  -0.400  -0.384
76    A        -1.082  -1.080  -1.039  -0.887  -0.895  -0.819  -0.942  -0.939  -0.879
77    S        -0.289  -0.283  -0.284  -0.556  -0.552  -0.559  -0.390  -0.382  -0.380
78    N        -0.289  -0.290  -0.289  -0.487  -0.490  -0.516  -0.390  -0.392  -0.387
79    Y        -1.082  -1.080  -1.039  -1.254  -1.242  -1.189  -0.942  -0.939  -0.879
80    I        -0.289  -0.311  -0.304  -0.204  -0.242  -0.236  -0.390  -0.420  -0.407
81    S        -0.289  -0.277  -0.277  -0.635  -0.618  -0.631  -0.390  -0.374  -0.370
82    S         2.091   2.096   2.141   1.813   1.821   1.898   2.371   2.377   2.451
83    Q        -0.289  -0.262  -0.307  -0.340  -0.285  -0.410  -0.390  -0.352  -0.412
84    A        -0.289  -0.311  -0.304  -0.486  -0.515  -0.487  -0.390  -0.420  -0.407
85    S        -0.289  -0.262  -0.307  -0.592  -0.554  -0.610  -0.390  -0.352  -0.412
86    S         0.505   0.507   0.551  -0.063  -0.059   0.012   0.162   0.166   0.231
87    S        -0.289  -0.262  -0.307  -0.722  -0.678  -0.758  -0.390  -0.352  -0.412
88    T        -0.289  -0.262  -0.307  -0.330  -0.294  -0.345  -0.390  -0.352  -0.412
89    S         0.804   0.831   0.740   0.456   0.500   0.342   0.714   0.761   0.587
90    V        -0.289  -0.283  -0.284  -0.548  -0.540  -0.531  -0.390  -0.382  -0.380
91    T         2.091   2.096   2.141   1.998   2.004   2.083   2.371   2.377   2.451
92    T        -0.289  -0.296  -0.287  -0.519  -0.543  -0.524  -0.390  -0.400  -0.384
93    V        -1.082  -1.080  -1.039  -0.880  -0.868  -0.812  -0.942  -0.939  -0.879
94    T        -0.289  -0.290  -0.289  -0.578  -0.591  -0.592  -0.390  -0.392  -0.387
95    -        -0.423  -0.420  -0.379  -0.720  -0.726  -0.651  -0.574  -0.569  -0.509
96    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
97    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
98    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
99    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
100   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
101   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
102   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
103   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
104   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
105   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -         0.634   0.664   0.651   0.384   0.429   0.420   0.408   0.462   0.422
111   -         0.634   0.642   0.645   0.304   0.318   0.324   0.408   0.421   0.410
112   -         0.634   0.642   0.645   0.263   0.279   0.260   0.408   0.421   0.410
113   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
115   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
123   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
124   T        -0.958  -0.938  -0.970  -0.758  -0.727  -0.790  -0.809  -0.787  -0.806
125   I        -0.958  -0.934  -0.946  -0.781  -0.745  -0.765  -0.809  -0.781  -0.781
126   A        -0.958  -0.940  -0.951  -0.732  -0.699  -0.728  -0.809  -0.789  -0.786
127   T        -0.958  -0.984  -0.956  -1.079  -1.126  -1.083  -0.809  -0.837  -0.791
128   S        -0.084  -0.083  -0.204  -0.155  -0.153  -0.293  -0.103  -0.101  -0.268
129   I        -1.593  -1.592  -1.551  -1.710  -1.707  -1.647  -1.163  -1.160  -1.101
130   R        -0.084  -0.069  -0.169  -0.286  -0.265  -0.410  -0.103  -0.082  -0.220
131   S        -0.958  -0.938  -0.970  -0.859  -0.819  -0.901  -0.809  -0.787  -0.806
132   T        -0.958  -0.956  -0.972  -0.730  -0.723  -0.751  -0.809  -0.807  -0.808
133   P        -1.593  -1.592  -1.551  -1.230  -1.230  -1.164  -1.163  -1.160  -1.101
134   S        -1.593  -1.592  -1.551  -1.398  -1.390  -1.333  -1.163  -1.160  -1.101
135   N         0.551   0.552   0.573   0.217   0.218   0.226   0.251   0.251   0.273
136   L        -0.958  -0.969  -0.972  -1.104  -1.124  -1.126  -0.809  -0.821  -0.808
137   L        -0.323  -0.333  -0.306  -0.348  -0.349  -0.314  -0.456  -0.465  -0.421
138   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
139   F        -0.423  -0.422  -0.379  -0.424  -0.428  -0.353  -0.574  -0.571  -0.509
140   S        -0.958  -0.965  -0.958  -1.018  -1.025  -0.997  -0.809  -0.816  -0.793
141   N        -0.958  -0.954  -0.953  -1.018  -1.008  -0.992  -0.809  -0.805  -0.788
142   V         0.946   0.925   0.839   1.091   1.057   0.917   0.957   0.922   0.764
143   A        -0.084  -0.107  -0.180   0.002  -0.043  -0.198  -0.103  -0.135  -0.234
144   A        -1.082  -1.077  -1.039  -1.195  -1.175  -1.129  -0.942  -0.936  -0.879
145   Q        -1.593  -1.592  -1.551  -1.397  -1.397  -1.332  -1.163  -1.160  -1.101
146   P         0.551   0.561   0.589   0.159   0.175   0.222   0.251   0.268   0.304
147   K        -0.423  -0.422  -0.379  -0.514  -0.510  -0.444  -0.574  -0.571  -0.509
148   S        -1.593  -1.592  -1.551  -1.533  -1.525  -1.469  -1.163  -1.160  -1.101
149   S        -1.593  -1.592  -1.551  -1.526  -1.517  -1.462  -1.163  -1.160  -1.101
150   S         0.946   0.986   0.845   0.985   1.049   0.812   0.957   1.023   0.775
151   A        -0.084  -0.072  -0.163   0.169   0.183   0.040  -0.103  -0.086  -0.211
152   S         2.091   2.096   2.141   1.820   1.831   1.905   2.371   2.377   2.451
153   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
154   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
155   -         0.804   0.776   0.751   0.619   0.571   0.526   0.714   0.665   0.606
156   T        -0.958  -0.938  -0.970  -0.888  -0.851  -0.908  -0.809  -0.787  -0.806
157   I         0.551   0.558   0.575   0.215   0.225   0.251   0.251   0.263   0.278
158   G         2.091   2.096   2.141   2.306   2.312   2.394   2.371   2.377   2.451
159   L         2.091   2.096   2.141   1.961   1.966   2.046   2.371   2.377   2.451
160   S         0.551   0.561   0.589   0.338   0.362   0.392   0.251   0.268   0.304
161   I         2.091   2.096   2.141   2.123   2.132   2.210   2.371   2.377   2.451
162   G         2.091   2.096   2.141   2.306   2.312   2.394   2.371   2.377   2.451
163   L         0.551   0.553   0.571   0.215   0.217   0.245   0.251   0.253   0.270
164   P         2.091   2.096   2.141   2.231   2.237   2.318   2.371   2.377   2.451
165   I         2.091   2.096   2.141   2.123   2.132   2.210   2.371   2.377   2.451
166   G         0.551   0.561   0.589   0.608   0.623   0.671   0.251   0.268   0.304
167   I        -0.084  -0.110  -0.164  -0.037  -0.080  -0.171  -0.103  -0.139  -0.212
168   F        -0.084  -0.075  -0.175   0.338   0.353   0.197  -0.103  -0.090  -0.228
169   C        -0.323  -0.303  -0.319  -0.437  -0.413  -0.399  -0.456  -0.433  -0.436
170   F        -0.958  -0.956  -0.972  -0.828  -0.832  -0.845  -0.809  -0.807  -0.808
171   G        -0.323  -0.312  -0.311  -0.167  -0.145  -0.150  -0.456  -0.442  -0.427
172   L        -0.958  -0.963  -0.975  -0.822  -0.827  -0.817  -0.809  -0.814  -0.812
173   L        -0.323  -0.303  -0.305  -0.368  -0.338  -0.342  -0.456  -0.433  -0.420
174   I        -0.084  -0.107  -0.180   0.121   0.089  -0.003  -0.103  -0.135  -0.234
175   L        -0.084  -0.085  -0.169  -0.141  -0.144  -0.267  -0.103  -0.104  -0.219
176   L        -0.289  -0.296  -0.287  -0.263  -0.272  -0.244  -0.390  -0.400  -0.384
177   C        -1.082  -1.080  -1.039  -0.880  -0.868  -0.812  -0.942  -0.939  -0.879
178   Y        -0.323  -0.334  -0.319   0.070   0.062   0.093  -0.456  -0.467  -0.437
179   F        -0.084  -0.117  -0.165   0.271   0.220   0.133  -0.103  -0.149  -0.213
180   Y         0.946   0.938   0.836   1.313   1.307   1.171   0.957   0.943   0.760
181   L        -0.958  -0.984  -0.956  -0.922  -0.956  -0.906  -0.809  -0.837  -0.791
182   K         0.551   0.571   0.577   0.484   0.525   0.514   0.251   0.288   0.280
183   R        -0.289  -0.262  -0.307  -0.170  -0.121  -0.213  -0.390  -0.352  -0.412
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   N        -0.958  -0.969  -0.972  -0.966  -0.988  -1.003  -0.809  -0.821  -0.808
187   S        -0.289  -0.301  -0.302  -0.572  -0.595  -0.622  -0.390  -0.408  -0.405
188   V        -0.289  -0.312  -0.307  -0.189  -0.218  -0.228  -0.390  -0.423  -0.412
189   S         0.634   0.636   0.626   0.328   0.336   0.323   0.408   0.410   0.375
190   I        -0.423  -0.422  -0.379  -0.410  -0.406  -0.339  -0.574  -0.571  -0.509
191   S        -0.423  -0.422  -0.379  -0.702  -0.689  -0.633  -0.574  -0.571  -0.509
192   N         2.091   2.096   2.141   2.138   2.145   2.225   2.371   2.377   2.451
193   P        -0.289  -0.311  -0.304  -0.305  -0.339  -0.324  -0.390  -0.420  -0.407
194   P        -0.289  -0.311  -0.304  -0.132  -0.171  -0.165  -0.390  -0.420  -0.407
195   M        -0.958  -0.963  -0.975  -0.490  -0.500  -0.522  -0.809  -0.814  -0.812
196   S        -0.958  -0.969  -0.972  -1.028  -1.034  -1.021  -0.809  -0.821  -0.808
197   A        -0.958  -0.940  -0.951  -0.720  -0.699  -0.695  -0.809  -0.789  -0.786
198   T        -0.958  -0.965  -0.958  -0.848  -0.851  -0.836  -0.809  -0.816  -0.793
199   I        -0.323  -0.334  -0.319  -0.519  -0.534  -0.498  -0.456  -0.467  -0.437
200   P        -0.084  -0.107  -0.180   0.047   0.007  -0.122  -0.103  -0.135  -0.234
201   R        -0.289  -0.268  -0.304  -0.009   0.025  -0.024  -0.390  -0.361  -0.407
202   E        -1.082  -1.081  -1.039  -1.248  -1.254  -1.182  -0.942  -0.940  -0.879
203   E         0.804   0.830   0.746   0.970   1.011   0.871   0.714   0.759   0.597
204   E        -0.289  -0.297  -0.287  -0.280  -0.298  -0.294  -0.390  -0.401  -0.384
205   Y         0.804   0.784   0.750   1.130   1.105   1.061   0.714   0.679   0.605
206   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   T         0.634   0.636   0.626   0.544   0.550   0.532   0.408   0.410   0.375
210   N        -0.423  -0.422  -0.379  -0.658  -0.650  -0.589  -0.574  -0.571  -0.509
211   W        -0.423  -0.422  -0.379  -0.271  -0.277  -0.199  -0.574  -0.571  -0.509
212   F         0.634   0.636   0.626   0.709   0.711   0.665   0.408   0.410   0.375
213   S         0.634   0.636   0.626   0.328   0.333   0.323   0.408   0.410   0.375
214   R        -0.423  -0.422  -0.379  -0.689  -0.696  -0.620  -0.574  -0.571  -0.509
215   L         2.091   2.096   2.141   1.954   1.957   2.039   2.371   2.377   2.451
216   F        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
218   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
219   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
220   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
221   C        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
222   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
223   D         2.091   2.096   2.141   2.293   2.305   2.380   2.371   2.377   2.451
224   Q         0.634   0.636   0.626   0.620   0.622   0.578   0.408   0.410   0.375
225   N        -0.423  -0.422  -0.379  -0.529  -0.528  -0.459  -0.574  -0.571  -0.509
226   S        -0.423  -0.422  -0.379  -0.570  -0.554  -0.500  -0.574  -0.571  -0.509
227   Y        -0.423  -0.422  -0.379  -0.362  -0.362  -0.291  -0.574  -0.571  -0.509
228   S        -0.423  -0.422  -0.379  -0.591  -0.576  -0.522  -0.574  -0.571  -0.509
229   N         0.634   0.654   0.628   0.362   0.390   0.346   0.408   0.443   0.378
230   R        -0.423  -0.422  -0.379  -0.233  -0.233  -0.161  -0.574  -0.571  -0.509
231   D        -0.423  -0.422  -0.379  -0.379  -0.376  -0.308  -0.574  -0.571  -0.509
232   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   E         0.804   0.829   0.737   0.896   0.936   0.773   0.714   0.757   0.581
234   K         0.804   0.744   0.716   0.862   0.774   0.747   0.714   0.606   0.542
235   Y        -1.082  -1.077  -1.039  -1.016  -1.038  -0.949  -0.942  -0.936  -0.879
236   N        -0.289  -0.269  -0.287  -0.289  -0.256  -0.288  -0.390  -0.362  -0.384
237   D         2.091   2.096   2.141   2.289   2.300   2.377   2.371   2.377   2.451
238   T        -0.289  -0.246  -0.284  -0.149  -0.080  -0.142  -0.390  -0.330  -0.380
239   Q        -0.289  -0.246  -0.284  -0.305  -0.244  -0.294  -0.390  -0.330  -0.380
240   W        -1.082  -1.077  -1.039  -0.742  -0.760  -0.673  -0.942  -0.936  -0.879
241   T        -0.289  -0.269  -0.287  -0.484  -0.446  -0.491  -0.390  -0.362  -0.384
242   S        -0.289  -0.312  -0.307  -0.394  -0.410  -0.389  -0.390  -0.423  -0.412
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   G        -0.289  -0.287  -0.287  -0.236  -0.234  -0.221  -0.390  -0.388  -0.383
246   D         0.804   0.800   0.751   0.796   0.790   0.721   0.714   0.706   0.606
247   N        -1.593  -1.592  -1.551  -1.354  -1.354  -1.289  -1.163  -1.160  -1.101
248   M        -1.593  -1.592  -1.551  -1.239  -1.247  -1.173  -1.163  -1.160  -1.101
249   S        -0.084  -0.083  -0.204  -0.216  -0.213  -0.371  -0.103  -0.101  -0.268
250   S         0.946   0.938   0.836   0.767   0.761   0.626   0.957   0.943   0.760
251   K        -0.958  -0.963  -0.975  -1.056  -1.060  -1.098  -0.809  -0.814  -0.812
252   I        -0.958  -0.963  -0.975  -0.674  -0.684  -0.679  -0.809  -0.814  -0.812
253   Q        -0.958  -0.934  -0.946  -1.021  -0.990  -1.004  -0.809  -0.781  -0.781
254   Y        -0.323  -0.328  -0.320  -0.380  -0.386  -0.370  -0.456  -0.460  -0.438
255   K        -0.958  -0.963  -0.975  -0.880  -0.894  -0.901  -0.809  -0.814  -0.812
256   I        -0.958  -0.969  -0.972  -0.934  -0.945  -0.962  -0.809  -0.821  -0.808
257   S        -0.323  -0.332  -0.313  -0.666  -0.673  -0.627  -0.456  -0.465  -0.430
258   K         0.946   0.938   0.836   1.039   1.027   0.897   0.957   0.943   0.760
259   P        -0.084  -0.075  -0.175   0.224   0.236   0.103  -0.103  -0.090  -0.228
260   I        -0.958  -0.934  -0.946  -0.767  -0.723  -0.759  -0.809  -0.781  -0.781
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   I         2.091   2.096   2.141   2.157   2.163   2.243   2.371   2.377   2.451
263   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
264   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
265   P         2.091   2.096   2.141   2.204   2.211   2.291   2.371   2.377   2.451
266   Q         0.634   0.636   0.626   0.747   0.751   0.725   0.408   0.410   0.375
267   H        -0.423  -0.422  -0.379  -0.301  -0.297  -0.229  -0.574  -0.571  -0.509
268   I         0.634   0.621   0.623   0.611   0.587   0.590   0.408   0.382   0.369
269   L        -0.423  -0.422  -0.379  -0.376  -0.366  -0.305  -0.574  -0.571  -0.509
270   T         0.634   0.621   0.623   0.635   0.618   0.632   0.408   0.382   0.369
271   P         2.091   2.096   2.141   2.204   2.211   2.291   2.371   2.377   2.451
272   K        -0.423  -0.422  -0.379  -0.662  -0.666  -0.592  -0.574  -0.571  -0.509
273   K         0.634   0.621   0.623   0.533   0.508   0.514   0.408   0.382   0.369
274   T         0.634   0.636   0.626   0.385   0.387   0.349   0.408   0.410   0.375
275   V         0.634   0.654   0.628   0.716   0.747   0.700   0.408   0.443   0.378
276   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   K         0.634   0.654   0.628   0.646   0.686   0.616   0.408   0.443   0.378
279   N         2.091   2.096   2.141   2.138   2.142   2.224   2.371   2.377   2.451
280   P         0.634   0.621   0.623   0.594   0.567   0.561   0.408   0.382   0.369
281   Y         0.634   0.621   0.623   0.624   0.598   0.575   0.408   0.382   0.369
282   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
283   W         0.634   0.654   0.628   0.851   0.880   0.847   0.408   0.443   0.378
284   S        -0.423  -0.422  -0.379  -0.807  -0.800  -0.738  -0.574  -0.571  -0.509
285   G         0.634   0.636   0.626   0.676   0.676   0.647   0.408   0.410   0.375
286   K        -0.423  -0.422  -0.379  -0.714  -0.717  -0.645  -0.574  -0.571  -0.509
287   N         2.091   2.096   2.141   2.138   2.142   2.224   2.371   2.377   2.451
288   I        -0.423  -0.422  -0.379  -0.555  -0.559  -0.485  -0.574  -0.571  -0.509
289   S        -0.423  -0.422  -0.379  -0.619  -0.604  -0.549  -0.574  -0.571  -0.509
290   L        -0.423  -0.422  -0.379  -0.794  -0.787  -0.725  -0.574  -0.571  -0.509
291   D         2.091   2.096   2.141   2.293   2.305   2.380   2.371   2.377   2.451
292   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
293   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
294   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
299   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
300   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
301   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
302   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
303   V        -0.423  -0.422  -0.379  -0.444  -0.444  -0.374  -0.574  -0.571  -0.509
304   D         0.634   0.636   0.626   0.676   0.682   0.647   0.408   0.410   0.375
305   A         0.634   0.621   0.623   0.654   0.625   0.620   0.408   0.382   0.369
306   F         0.634   0.654   0.628   0.830   0.866   0.822   0.408   0.443   0.378
307   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
309   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
310   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
311   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
312   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
313   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
317   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
318   E        -0.423  -0.422  -0.379  -0.591  -0.584  -0.522  -0.574  -0.571  -0.509
319   S         0.634   0.636   0.626   0.251   0.255   0.235   0.408   0.410   0.375
320   S         2.091   2.096   2.141   1.835   1.845   1.919   2.371   2.377   2.451
321   M        -0.423  -0.422  -0.379  -0.407  -0.407  -0.336  -0.574  -0.571  -0.509
322   P        -0.423  -0.422  -0.379  -0.517  -0.516  -0.447  -0.574  -0.571  -0.509
323   S        -1.593  -1.592  -1.551  -1.397  -1.386  -1.332  -1.163  -1.160  -1.101
324   Y        -0.084  -0.069  -0.169  -0.066  -0.049  -0.176  -0.103  -0.082  -0.220
325   N        -0.084  -0.117  -0.165   0.023  -0.031  -0.109  -0.103  -0.149  -0.213
326   D        -1.593  -1.592  -1.551  -1.042  -1.037  -0.975  -1.163  -1.160  -1.101
327   L        -1.593  -1.592  -1.551  -1.605  -1.593  -1.541  -1.163  -1.160  -1.101
328   P         2.091   2.096   2.141   2.231   2.237   2.318   2.371   2.377   2.451
329   S        -1.593  -1.592  -1.551  -1.374  -1.360  -1.309  -1.163  -1.160  -1.101
330   Q        -0.958  -0.984  -0.956  -0.630  -0.674  -0.630  -0.809  -0.837  -0.791
331   K        -1.593  -1.592  -1.551  -1.246  -1.247  -1.181  -1.163  -1.160  -1.101
332   T        -1.593  -1.592  -1.551  -1.166  -1.157  -1.099  -1.163  -1.160  -1.101
333   V        -1.593  -1.592  -1.551  -1.503  -1.516  -1.439  -1.163  -1.160  -1.101
334   S        -1.593  -1.592  -1.551  -1.317  -1.302  -1.252  -1.163  -1.160  -1.101
335   S        -0.958  -0.938  -0.970  -0.719  -0.673  -0.761  -0.809  -0.787  -0.806
336   K        -0.084  -0.083  -0.204   0.010   0.011  -0.167  -0.103  -0.101  -0.268
337   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
338   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
344   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   K        -0.323  -0.328  -0.320  -0.412  -0.420  -0.422  -0.456  -0.460  -0.438
346   W        -0.084  -0.083  -0.204   0.467   0.470   0.287  -0.103  -0.101  -0.268
347   S        -1.593  -1.592  -1.551  -1.725  -1.710  -1.662  -1.163  -1.160  -1.101
348   Y        -0.084  -0.083  -0.204   0.117   0.120  -0.116  -0.103  -0.101  -0.268
349   E        -0.958  -0.963  -0.975  -0.683  -0.696  -0.705  -0.809  -0.814  -0.812
350   S        -0.084  -0.083  -0.204  -0.267  -0.259  -0.437  -0.103  -0.101  -0.268
351   P        -0.084  -0.083  -0.204  -0.024  -0.020  -0.260  -0.103  -0.101  -0.268
352   L        -0.084  -0.083  -0.204  -0.084  -0.084  -0.247  -0.103  -0.101  -0.268
353   S        -0.084  -0.083  -0.204  -0.268  -0.261  -0.439  -0.103  -0.101  -0.268
354   R        -0.084  -0.075  -0.175   0.143   0.155  -0.013  -0.103  -0.090  -0.228
355   W        -0.084  -0.083  -0.204   0.374   0.373   0.168  -0.103  -0.101  -0.268
356   F         0.946   0.928   0.821   1.283   1.259   1.080   0.957   0.928   0.732
357   L        -0.084  -0.083  -0.204  -0.166  -0.166  -0.353  -0.103  -0.101  -0.268
358   R         0.946   0.925   0.839   1.170   1.138   1.001   0.957   0.922   0.764
359   G        -0.958  -0.956  -0.972  -1.139  -1.147  -1.166  -0.809  -0.807  -0.808
360   S         2.091   2.096   2.141   1.820   1.831   1.905   2.371   2.377   2.451
361   T        -0.958  -0.963  -0.975  -1.019  -1.034  -1.048  -0.809  -0.814  -0.812
362   Y        -0.958  -0.969  -0.972  -0.967  -0.993  -1.035  -0.809  -0.821  -0.808
363   F        -0.958  -0.965  -0.958  -0.710  -0.724  -0.726  -0.809  -0.816  -0.793
364   K        -0.958  -0.938  -0.970  -0.698  -0.663  -0.730  -0.809  -0.787  -0.806
365   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
366   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
367   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
368   L        -0.958  -0.956  -0.972  -0.766  -0.754  -0.775  -0.809  -0.807  -0.808
369   S        -0.323  -0.334  -0.319  -0.545  -0.556  -0.535  -0.456  -0.467  -0.437
370   K        -0.958  -0.965  -0.958  -1.078  -1.093  -1.091  -0.809  -0.816  -0.793
371   T        -1.593  -1.592  -1.551  -1.356  -1.353  -1.291  -1.163  -1.160  -1.101
372   S        -0.958  -0.961  -0.956  -1.015  -1.013  -1.026  -0.809  -0.812  -0.791
373   L        -0.958  -0.969  -0.972  -0.961  -0.981  -0.967  -0.809  -0.821  -0.808
374   K        -0.323  -0.332  -0.313  -0.495  -0.509  -0.469  -0.456  -0.465  -0.430
375   T        -0.958  -0.963  -0.975  -0.917  -0.927  -0.934  -0.809  -0.814  -0.812
376   P        -0.958  -0.963  -0.975  -0.917  -0.932  -0.965  -0.809  -0.814  -0.812
377   T        -0.323  -0.312  -0.311  -0.666  -0.653  -0.636  -0.456  -0.442  -0.427
378   G        -0.289  -0.305  -0.304  -0.474  -0.509  -0.511  -0.390  -0.413  -0.407
379   A        -0.289  -0.287  -0.287  -0.359  -0.359  -0.346  -0.390  -0.388  -0.383
380   P        -0.323  -0.334  -0.319  -0.339  -0.356  -0.329  -0.456  -0.467  -0.437
381   Q        -1.593  -1.592  -1.551  -1.020  -1.016  -0.953  -1.163  -1.160  -1.101
382   L        -0.958  -0.963  -0.975  -0.929  -0.937  -0.936  -0.809  -0.814  -0.812
383   K         2.091   2.096   2.141   2.085   2.090   2.171   2.371   2.377   2.451
384   Q        -0.289  -0.321  -0.307   0.049  -0.005   0.029  -0.390  -0.435  -0.412
385   M        -0.323  -0.334  -0.308  -0.467  -0.484  -0.448  -0.456  -0.467  -0.424
386   K        -0.958  -0.938  -0.970  -0.962  -0.935  -0.996  -0.809  -0.787  -0.806
387   M        -0.958  -0.938  -0.970  -0.809  -0.783  -0.821  -0.809  -0.787  -0.806
388   L         0.946   0.969   0.820   0.887   0.918   0.712   0.957   0.995   0.730
389   S        -0.323  -0.333  -0.306  -0.666  -0.668  -0.624  -0.456  -0.465  -0.421
390   R        -0.323  -0.328  -0.320  -0.346  -0.355  -0.358  -0.456  -0.460  -0.438
391   I        -0.084  -0.110  -0.164   0.069   0.032  -0.043  -0.103  -0.139  -0.212
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
398   S        -0.289  -0.305  -0.304  -0.588  -0.619  -0.627  -0.390  -0.413  -0.407
399   K        -0.289  -0.287  -0.289  -0.277  -0.275  -0.269  -0.390  -0.387  -0.387
400   G        -0.289  -0.305  -0.304  -0.471  -0.506  -0.508  -0.390  -0.413  -0.407
401   Y        -1.082  -1.081  -1.039  -1.015  -0.998  -0.948  -0.942  -0.940  -0.879
402   F        -0.289  -0.287  -0.287  -0.148  -0.141  -0.145  -0.390  -0.388  -0.383
403   N        -0.958  -0.963  -0.975  -0.627  -0.639  -0.632  -0.809  -0.814  -0.812
404   E         0.551   0.558   0.575   0.389   0.397   0.428   0.251   0.263   0.278
405   S        -0.323  -0.332  -0.313  -0.567  -0.577  -0.533  -0.456  -0.465  -0.430
406   D        -0.958  -0.956  -0.972  -0.794  -0.798  -0.812  -0.809  -0.807  -0.808
407   I        -0.084  -0.083  -0.204   0.070   0.072  -0.102  -0.103  -0.101  -0.268
408   M        -0.289  -0.301  -0.302  -0.225  -0.250  -0.228  -0.390  -0.408  -0.405
409   P        -0.423  -0.419  -0.379  -0.372  -0.356  -0.301  -0.574  -0.568  -0.509
410   D         0.634   0.654   0.645   0.623   0.658   0.639   0.408   0.444   0.410
411   E        -0.423  -0.419  -0.379  -0.573  -0.588  -0.503  -0.574  -0.568  -0.509
412   R         0.634   0.654   0.645   0.698   0.731   0.714   0.408   0.444   0.410
413   S         0.804   0.847   0.746   0.829   0.904   0.705   0.714   0.788   0.596
414   P        -0.289  -0.312  -0.307  -0.105  -0.142  -0.128  -0.390  -0.423  -0.412
415   I        -0.289  -0.301  -0.302  -0.228  -0.262  -0.276  -0.390  -0.408  -0.405
416   L        -1.082  -1.077  -1.039  -1.106  -1.090  -1.039  -0.942  -0.936  -0.879
417   E         0.804   0.744   0.716   0.976   0.881   0.840   0.714   0.606   0.542
418   Y        -1.082  -1.077  -1.039  -0.812  -0.818  -0.744  -0.942  -0.936  -0.879
419   N        -0.289  -0.269  -0.287  -0.512  -0.474  -0.531  -0.390  -0.362  -0.384
420   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
421   -        -0.423  -0.421  -0.379  -0.348  -0.361  -0.277  -0.574  -0.570  -0.509
422   -         2.091   2.096   2.141   1.917   1.921   2.002   2.371   2.377   2.451
423   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
424   N         0.634   0.654   0.628   0.251   0.284   0.237   0.408   0.443   0.378
425   T        -0.423  -0.422  -0.379  -0.640  -0.643  -0.570  -0.574  -0.571  -0.509
426   P         0.634   0.621   0.623   0.564   0.537   0.526   0.408   0.382   0.369
427   L        -0.423  -0.422  -0.379  -0.508  -0.504  -0.438  -0.574  -0.571  -0.509
428   D         0.634   0.654   0.628   0.328   0.362   0.326   0.408   0.443   0.378
429   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
430   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
431   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
432   S         0.634   0.636   0.626   0.316   0.321   0.310   0.408   0.410   0.375
433   V         0.634   0.654   0.628   0.614   0.644   0.601   0.408   0.443   0.378
434   N         0.634   0.636   0.626   0.581   0.581   0.564   0.408   0.410   0.375
435   N        -0.423  -0.422  -0.379  -0.807  -0.806  -0.738  -0.574  -0.571  -0.509
436   L         2.091   2.096   2.141   1.954   1.957   2.039   2.371   2.377   2.451
437   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
438   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
439   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
440   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
441   P         0.634   0.621   0.623   0.458   0.428   0.402   0.408   0.382   0.369
442   D        -0.423  -0.422  -0.379  -0.570  -0.565  -0.500  -0.574  -0.571  -0.509
443   S        -0.423  -0.422  -0.379  -0.886  -0.880  -0.818  -0.574  -0.571  -0.509
444   Q        -0.423  -0.422  -0.379  -0.301  -0.297  -0.229  -0.574  -0.571  -0.509
445   I        -0.423  -0.422  -0.379  -0.585  -0.585  -0.516  -0.574  -0.571  -0.509
446   T         0.634   0.654   0.628   0.440   0.473   0.415   0.408   0.443   0.378
447   S         0.634   0.636   0.626   0.302   0.307   0.294   0.408   0.410   0.375
448   Y        -0.423  -0.422  -0.379  -0.430  -0.432  -0.359  -0.574  -0.571  -0.509
449   R        -0.423  -0.422  -0.379  -0.579  -0.578  -0.509  -0.574  -0.571  -0.509
450   N        -0.423  -0.422  -0.379  -0.424  -0.423  -0.353  -0.574  -0.571  -0.509
451   N         0.634   0.636   0.626   0.542   0.542   0.518   0.408   0.410   0.375
452   N        -0.423  -0.422  -0.379  -0.570  -0.572  -0.500  -0.574  -0.571  -0.509
453   I         0.634   0.621   0.623   0.466   0.435   0.421   0.408   0.382   0.369
454   D         0.634   0.654   0.628   0.605   0.636   0.594   0.408   0.443   0.378
455   L         0.634   0.654   0.628   0.546   0.581   0.509   0.408   0.443   0.378
456   I         0.634   0.636   0.626   0.412   0.416   0.366   0.408   0.410   0.375
457   T         0.634   0.636   0.626   0.440   0.443   0.412   0.408   0.410   0.375
458   A        -0.423  -0.422  -0.379  -0.382  -0.381  -0.311  -0.574  -0.571  -0.509
459   R         0.634   0.621   0.623   0.663   0.635   0.622   0.408   0.382   0.369
460   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
461   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
462   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
463   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
464   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
465   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
466   G        -0.289  -0.312  -0.307   0.035  -0.005   0.015  -0.390  -0.423  -0.412
467   T        -0.958  -0.965  -0.958  -1.165  -1.172  -1.179  -0.809  -0.816  -0.793
468   T        -0.958  -0.954  -0.953  -0.938  -0.931  -0.935  -0.809  -0.805  -0.788
469   A        -0.084  -0.037  -0.162   0.053   0.117  -0.050  -0.103  -0.036  -0.209
470   Q        -0.084  -0.037  -0.162   0.205   0.271   0.100  -0.103  -0.036  -0.209
471   Q        -0.084  -0.075  -0.175   0.297   0.310   0.163  -0.103  -0.090  -0.228
472   T        -0.084  -0.037  -0.162   0.043   0.117  -0.071  -0.103  -0.036  -0.209
473   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
474   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
475   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
476   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
477   L         0.946   0.925   0.839   0.859   0.828   0.702   0.957   0.922   0.764
478   E        -0.323  -0.334  -0.319  -0.511  -0.525  -0.486  -0.456  -0.467  -0.437
479   T        -0.323  -0.328  -0.320  -0.569  -0.577  -0.569  -0.456  -0.460  -0.438
480   N         0.551   0.557   0.589   0.471   0.480   0.530   0.251   0.261   0.303
481   F        -1.593  -1.592  -1.551  -1.281  -1.291  -1.215  -1.163  -1.160  -1.101
482   N         0.946   0.925   0.839   1.049   1.017   0.886   0.957   0.922   0.764
483   D         0.551   0.571   0.577   0.548   0.581   0.588   0.251   0.288   0.280
484   H        -1.593  -1.592  -1.551  -1.427  -1.429  -1.362  -1.163  -1.160  -1.101
485   H        -0.958  -0.938  -0.970  -0.571  -0.543  -0.589  -0.809  -0.787  -0.806
486   D        -1.082  -1.080  -1.039  -0.957  -0.951  -0.889  -0.942  -0.939  -0.879
487   C        -1.082  -1.080  -1.039  -1.046  -1.042  -0.979  -0.942  -0.939  -0.879
488   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
489   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
490   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
491   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
492   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
493   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
494   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
495   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
496   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
497   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
498   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
499   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
500   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
501   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
502   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
503   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
504   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
505   L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
506   K         2.091   2.096   2.141   2.071   2.076   2.157   2.371   2.377   2.451
507   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
508   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
509   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
510   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
511   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
512   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
513   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
514   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
515   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
516   M        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
517   Y        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
518   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
519   H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
520   L        -0.084  -0.083  -0.204  -0.066  -0.062  -0.224  -0.103  -0.101  -0.268
521   Q        -0.289  -0.301  -0.302  -0.248  -0.289  -0.290  -0.390  -0.408  -0.405
522   H        -1.082  -1.077  -1.039  -0.799  -0.799  -0.731  -0.942  -0.936  -0.879
523   L         0.804   0.744   0.716   0.610   0.505   0.459   0.714   0.606   0.542
524   S        -0.289  -0.312  -0.307  -0.464  -0.492  -0.469  -0.390  -0.423  -0.412
525   R        -0.289  -0.301  -0.302  -0.167  -0.179  -0.167  -0.390  -0.408  -0.405
526   S        -0.289  -0.301  -0.302  -0.585  -0.606  -0.632  -0.390  -0.408  -0.405
527   K         2.091   2.096   2.141   2.085   2.090   2.171   2.371   2.377   2.451
528   P         2.091   2.096   2.141   2.231   2.237   2.318   2.371   2.377   2.451
529   L         0.946   0.928   0.821   0.836   0.808   0.640   0.957   0.928   0.732
530   P         0.946   0.928   0.821   1.169   1.145   0.996   0.957   0.928   0.732
531   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
532   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
533   L        -0.323  -0.332  -0.311  -0.576  -0.590  -0.547  -0.456  -0.465  -0.427
534   T        -0.323  -0.334  -0.319  -0.589  -0.604  -0.567  -0.456  -0.467  -0.437
535   P         2.091   2.096   2.141   2.231   2.237   2.318   2.371   2.377   2.451
536   N        -0.323  -0.328  -0.320  -0.371  -0.379  -0.368  -0.456  -0.460  -0.438
537   S        -0.958  -0.969  -0.972  -1.094  -1.104  -1.093  -0.809  -0.821  -0.808
538   K        -0.289  -0.311  -0.304  -0.226  -0.255  -0.243  -0.390  -0.420  -0.407
539   Y        -1.082  -1.080  -1.039  -0.882  -0.872  -0.813  -0.942  -0.939  -0.879
540   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
541   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
542   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
543   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
544   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
545   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
546   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
547   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
548   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
549   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
550   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
551   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
552   -         0.634   0.642   0.645   0.573   0.586   0.580   0.408   0.421   0.410
553   -        -0.423  -0.420  -0.379  -0.599  -0.608  -0.530  -0.574  -0.569  -0.509
554   -        -0.423  -0.420  -0.379  -0.744  -0.727  -0.675  -0.574  -0.569  -0.509
555   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
556   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
557   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
558   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
559   -         0.634   0.642   0.645   0.718   0.735   0.711   0.408   0.421   0.410
560   -        -0.423  -0.420  -0.379  -0.445  -0.433  -0.374  -0.574  -0.569  -0.509
561   -         2.091   2.096   2.141   1.999   2.007   2.084   2.371   2.377   2.451
562   -        -0.423  -0.420  -0.379  -0.451  -0.437  -0.381  -0.574  -0.569  -0.509
563   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
564   -        -0.423  -0.420  -0.379  -0.576  -0.557  -0.506  -0.574  -0.569  -0.509
565   N        -0.958  -0.961  -0.956  -1.046  -1.045  -1.025  -0.809  -0.812  -0.791
566   G        -0.958  -0.961  -0.956  -0.657  -0.668  -0.653  -0.809  -0.812  -0.791
567   E        -0.958  -0.954  -0.953  -1.058  -1.052  -1.034  -0.809  -0.805  -0.788
568   A        -1.593  -1.592  -1.551  -1.328  -1.332  -1.263  -1.163  -1.160  -1.101
569   S        -0.958  -0.956  -0.972  -0.999  -0.987  -1.035  -0.809  -0.807  -0.808
570   V        -1.593  -1.592  -1.551  -1.570  -1.575  -1.507  -1.163  -1.160  -1.101
571   Q        -1.593  -1.592  -1.551  -1.226  -1.234  -1.160  -1.163  -1.160  -1.101
572   L        -1.593  -1.592  -1.551  -1.253  -1.245  -1.187  -1.163  -1.160  -1.101
573   G        -0.958  -0.969  -0.972  -0.551  -0.569  -0.563  -0.809  -0.821  -0.808
574   K        -0.084  -0.107  -0.180  -0.155  -0.197  -0.335  -0.103  -0.135  -0.234
575   T        -0.958  -0.934  -0.946  -0.863  -0.830  -0.832  -0.809  -0.781  -0.781
576   Y         2.091   2.096   2.141   2.349   2.360   2.437   2.371   2.377   2.451
577   T        -0.323  -0.312  -0.313  -0.396  -0.376  -0.381  -0.456  -0.442  -0.429
578   V         2.091   2.096   2.141   2.234   2.240   2.321   2.371   2.377   2.451
579   I        -0.084  -0.110  -0.164   0.069   0.032  -0.043  -0.103  -0.139  -0.212
580   Q        -0.958  -0.954  -0.953  -0.748  -0.748  -0.728  -0.809  -0.805  -0.788
581   D        -0.958  -0.963  -0.975  -0.814  -0.828  -0.860  -0.809  -0.814  -0.812
582   Y         2.091   2.096   2.141   2.349   2.360   2.437   2.371   2.377   2.451
583   E        -0.958  -0.961  -0.956  -0.683  -0.690  -0.676  -0.809  -0.812  -0.791
584   P        -0.323  -0.334  -0.319  -0.331  -0.348  -0.310  -0.456  -0.467  -0.437
585   R        -0.958  -0.940  -0.951  -1.046  -1.024  -1.020  -0.809  -0.789  -0.786
586   L         2.091   2.096   2.141   1.961   1.966   2.046   2.371   2.377   2.451
587   T        -1.593  -1.592  -1.551  -1.361  -1.352  -1.296  -1.163  -1.160  -1.101
588   D         2.091   2.096   2.141   2.297   2.304   2.384   2.371   2.377   2.451
589   E         2.091   2.096   2.141   2.237   2.242   2.325   2.371   2.377   2.451
590   I         0.946   0.928   0.821   0.980   0.955   0.776   0.957   0.928   0.732
591   R        -1.593  -1.592  -1.551  -1.292  -1.282  -1.226  -1.163  -1.160  -1.101
592   I         0.946   0.938   0.836   1.048   1.038   0.895   0.957   0.943   0.760
593   S        -1.593  -1.592  -1.551  -1.603  -1.588  -1.539  -1.163  -1.160  -1.101
594   L        -0.084  -0.072  -0.163   0.092   0.113  -0.039  -0.103  -0.086  -0.211
595   G         2.091   2.096   2.141   2.306   2.312   2.394   2.371   2.377   2.451
596   E         0.551   0.553   0.571   0.553   0.554   0.584   0.251   0.253   0.270
597   K        -0.958  -0.965  -0.958  -0.997  -1.017  -1.002  -0.809  -0.816  -0.793
598   V         0.946   0.928   0.821   1.172   1.147   0.999   0.957   0.928   0.732
599   K        -0.084  -0.069  -0.169   0.166   0.189   0.025  -0.103  -0.082  -0.220
600   I         0.551   0.543   0.585   0.420   0.406   0.475   0.251   0.235   0.296
601   L         2.091   2.096   2.141   1.961   1.966   2.046   2.371   2.377   2.451
602   A        -0.084  -0.083  -0.204   0.151   0.152  -0.054  -0.103  -0.101  -0.268
603   T        -1.593  -1.592  -1.551  -1.603  -1.602  -1.539  -1.163  -1.160  -1.101
604   H         2.091   2.096   2.141   2.475   2.483   2.563   2.371   2.377   2.451
605   T        -0.323  -0.328  -0.320  -0.720  -0.724  -0.705  -0.456  -0.460  -0.438
606   D         2.091   2.096   2.141   2.297   2.304   2.384   2.371   2.377   2.451
607   G         2.091   2.096   2.141   2.306   2.312   2.394   2.371   2.377   2.451
608   W         2.091   2.096   2.141   2.502   2.510   2.590   2.371   2.377   2.451
609   C         0.946   0.938   0.836   1.427   1.417   1.273   0.957   0.943   0.760
610   L        -0.084  -0.083  -0.204  -0.292  -0.289  -0.517  -0.103  -0.101  -0.268
611   V        -0.084  -0.083  -0.204   0.138   0.136  -0.050  -0.103  -0.101  -0.268
612   E         0.551   0.553   0.571   0.553   0.553   0.584   0.251   0.253   0.270
613   K        -0.323  -0.303  -0.319  -0.446  -0.416  -0.436  -0.456  -0.433  -0.436
614   C        -0.958  -0.961  -0.956  -0.847  -0.862  -0.841  -0.809  -0.812  -0.791
615   N        -0.323  -0.332  -0.313  -0.274  -0.287  -0.243  -0.456  -0.465  -0.430
616   T        -1.593  -1.592  -1.551  -1.250  -1.242  -1.184  -1.163  -1.160  -1.101
617   Q        -0.958  -0.963  -0.975  -0.770  -0.779  -0.819  -0.809  -0.814  -0.812
618   K        -0.958  -0.965  -0.958  -0.826  -0.839  -0.817  -0.809  -0.816  -0.793
619   G         0.634   0.597   0.626   0.766   0.700   0.749   0.408   0.336   0.375
620   S        -0.423  -0.418  -0.379  -0.696  -0.662  -0.627  -0.574  -0.566  -0.509
621   I        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
622   H         0.634   0.621   0.623   0.735   0.703   0.682   0.408   0.382   0.369
623   V         0.634   0.636   0.626   0.524   0.527   0.475   0.408   0.410   0.375
624   S         2.091   2.096   2.141   1.835   1.845   1.919   2.371   2.377   2.451
625   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
626   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
627   D        -0.958  -0.956  -0.972  -0.715  -0.712  -0.751  -0.809  -0.807  -0.808
628   K        -1.593  -1.592  -1.551  -1.530  -1.518  -1.466  -1.163  -1.160  -1.101
629   R        -1.593  -1.592  -1.551  -1.427  -1.428  -1.362  -1.163  -1.160  -1.101
630   Y         0.946   0.928   0.821   1.298   1.278   1.126   0.957   0.928   0.732
631   L        -0.084  -0.075  -0.175  -0.209  -0.196  -0.360  -0.103  -0.090  -0.228
632   N         0.551   0.553   0.571   0.217   0.221   0.221   0.251   0.253   0.270
633   E        -0.084  -0.083  -0.204   0.029   0.025  -0.193  -0.103  -0.101  -0.268
634   D        -0.323  -0.312  -0.313  -0.306  -0.291  -0.286  -0.456  -0.442  -0.429
635   R        -0.084  -0.083  -0.204   0.213   0.213   0.026  -0.103  -0.101  -0.268
636   G         2.091   2.096   2.141   2.306   2.312   2.394   2.371   2.377   2.451
637   I        -0.084  -0.083  -0.204  -0.037  -0.038  -0.241  -0.103  -0.101  -0.268
638   V         0.551   0.556   0.572   0.452   0.460   0.475   0.251   0.259   0.272
639   P         2.091   2.096   2.141   2.231   2.237   2.318   2.371   2.377   2.451
640   G        -0.958  -0.963  -0.975  -0.707  -0.721  -0.742  -0.809  -0.814  -0.812
641   D        -0.958  -0.954  -0.953  -0.864  -0.861  -0.841  -0.809  -0.805  -0.788
642   C         2.091   2.096   2.141   2.496   2.504   2.584   2.371   2.377   2.451
643   L         2.091   2.096   2.141   1.961   1.966   2.046   2.371   2.377   2.451
644   Q         0.946   0.938   0.836   1.205   1.193   1.026   0.957   0.943   0.760
645   E        -0.323  -0.328  -0.320  -0.495  -0.507  -0.506  -0.456  -0.460  -0.438
646   Y        -1.082  -1.080  -1.039  -1.016  -1.026  -0.949  -0.942  -0.939  -0.879
647   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P11710
Output conservation file - output/P11710
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
