1     M         1.192   1.219   1.298   1.429   1.467   1.572   1.264   1.300   1.419
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     S         0.459   0.337   0.184   0.618   0.488   0.251   0.464   0.278  -0.012
5     D         1.192   1.219   1.298   1.099   1.144   1.274   1.264   1.300   1.419
6     E         0.098   0.146   0.097  -0.415  -0.339  -0.397  -0.108  -0.033  -0.168
7     I        -0.239  -0.385  -0.564   0.110  -0.080  -0.401  -0.222  -0.413  -0.659
8     V        -0.095  -0.085   0.056  -0.126  -0.113   0.074  -0.451  -0.443  -0.244
9     W         1.192   1.219   1.298   1.410   1.448   1.555   1.264   1.300   1.419
10    Q         0.459   0.442   0.192   0.633   0.609   0.131   0.464   0.438   0.003
11    V        -0.559  -0.541  -0.609  -0.351  -0.353  -0.430  -0.680  -0.682  -0.725
12    I        -0.239  -0.385  -0.564   0.110  -0.080  -0.401  -0.222  -0.413  -0.659
13    N         0.459   0.337   0.184   0.705   0.568   0.327   0.464   0.278  -0.012
14    Q        -0.559  -0.601  -0.612  -0.297  -0.355  -0.417  -0.680  -0.729  -0.728
15    S        -0.896  -0.852  -1.096  -0.526  -0.524  -0.924  -0.794  -0.744  -0.985
16    F         1.192   1.219   1.298   1.431   1.466   1.574   1.264   1.300   1.419
17    C         1.192   1.219   1.298   1.424   1.461   1.568   1.264   1.300   1.419
18    S        -0.095  -0.094   0.055  -0.217  -0.221  -0.023  -0.451  -0.459  -0.247
19    H        -0.703  -0.623  -0.616  -0.398  -0.297  -0.275  -0.908  -0.804  -0.736
20    R         0.098   0.070   0.082  -0.139  -0.182  -0.180  -0.108  -0.163  -0.196
21    I        -0.913  -0.888  -0.668  -0.910  -0.882  -0.594  -1.137  -1.090  -0.797
22    K         1.192   1.219   1.298   0.961   1.005   1.148   1.264   1.300   1.419
23    A         0.394   0.446   0.166   0.642   0.707   0.279   0.368   0.444  -0.044
24    P        -1.377  -1.334  -1.168  -1.194  -1.118  -0.873  -1.366  -1.308  -1.062
25    N        -0.239  -0.296  -0.556  -0.306  -0.410  -0.820  -0.222  -0.301  -0.649
26    G        -0.239  -0.253  -0.541   0.041   0.027  -0.526  -0.222  -0.250  -0.629
27    Q         0.459   0.347   0.186   0.712   0.581   0.329   0.464   0.293  -0.009
28    N        -0.239  -0.171  -0.539   0.098   0.182  -0.358  -0.222  -0.132  -0.626
29    F         1.192   1.219   1.298   1.431   1.466   1.574   1.264   1.300   1.419
30    C         1.192   1.219   1.298   1.424   1.461   1.568   1.264   1.300   1.419
31    R         0.459   0.442   0.192   0.525   0.507   0.098   0.464   0.438   0.003
32    N         1.192   1.219   1.298   1.293   1.335   1.449   1.264   1.300   1.419
33    E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
34    Y         1.192   1.219   1.298   1.346   1.386   1.497   1.264   1.300   1.419
35    N         1.192   1.219   1.298   1.293   1.335   1.449   1.264   1.300   1.419
36    V         1.192   1.219   1.298   1.240   1.286   1.401   1.264   1.300   1.419
37    T        -0.095  -0.056   0.066  -0.100  -0.037   0.096  -0.451  -0.388  -0.225
38    G         1.192   1.219   1.298   1.318   1.355   1.472   1.264   1.300   1.419
39    L        -0.239  -0.377  -0.564   0.002  -0.158  -0.394  -0.222  -0.401  -0.659
40    C         1.192   1.219   1.298   1.424   1.461   1.568   1.264   1.300   1.419
41    T        -1.250  -1.175  -1.126  -1.145  -1.023  -1.017  -1.252  -1.143  -1.021
42    R         1.192   1.219   1.298   1.163   1.200   1.331   1.264   1.300   1.419
43    Q         0.459   0.442   0.192   0.666   0.647   0.220   0.464   0.438   0.003
44    S         0.459   0.595   0.205   0.603   0.774   0.246   0.464   0.655   0.025
45    C         1.192   1.219   1.298   1.424   1.461   1.568   1.264   1.300   1.419
46    P         1.192   1.219   1.298   1.404   1.439   1.550   1.264   1.300   1.419
47    L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
48    A         1.192   1.219   1.298   1.199   1.238   1.364   1.264   1.300   1.419
49    N         1.192   1.219   1.298   1.293   1.335   1.449   1.264   1.300   1.419
50    S         1.192   1.219   1.298   1.208   1.256   1.372   1.264   1.300   1.419
51    K        -0.156  -0.109   0.057  -0.539  -0.448  -0.199  -0.565  -0.488  -0.243
52    Y         1.192   1.219   1.298   1.346   1.386   1.497   1.264   1.300   1.419
53    A         1.192   1.219   1.298   1.199   1.238   1.364   1.264   1.300   1.419
54    T         1.192   1.219   1.298   1.333   1.371   1.486   1.264   1.300   1.419
55    V         1.192   1.219   1.298   1.240   1.286   1.401   1.264   1.300   1.419
56    K        -0.095  -0.115   0.055  -0.453  -0.480  -0.205  -0.451  -0.499  -0.246
57    C        -2.052  -2.095  -1.901  -1.609  -1.749  -1.520  -1.595  -1.607  -1.349
58    D        -1.168  -1.196  -1.143  -1.103  -1.145  -1.200  -1.137  -1.162  -1.038
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    N        -1.168  -1.089  -1.117  -0.974  -0.851  -0.969  -1.137  -1.020  -1.010
61    G         1.192   1.219   1.298   1.318   1.355   1.472   1.264   1.300   1.419
62    K        -0.831  -0.798  -0.662  -1.008  -0.952  -0.743  -1.023  -0.971  -0.788
63    L         0.459   0.347   0.186   0.555   0.423   0.203   0.464   0.293  -0.009
64    Y         1.192   1.219   1.298   1.346   1.386   1.497   1.264   1.300   1.419
65    L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
66    Y         1.192   1.219   1.298   1.346   1.386   1.497   1.264   1.300   1.419
67    M         0.098   0.090   0.085   0.360   0.342   0.261  -0.108  -0.128  -0.191
68    K         0.459   0.574   0.205   0.351   0.495   0.021   0.464   0.626   0.025
69    T         1.192   1.219   1.298   1.333   1.371   1.486   1.264   1.300   1.419
70    P        -1.168  -1.110  -1.141  -0.883  -0.839  -0.835  -1.137  -1.094  -1.036
71    E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
72    R         1.192   1.219   1.298   1.163   1.200   1.331   1.264   1.300   1.419
73    A        -0.559  -0.472  -0.579  -0.399  -0.263  -0.438  -0.680  -0.537  -0.681
74    H         1.192   1.219   1.298   1.416   1.454   1.561   1.264   1.300   1.419
75    T        -0.703  -0.763  -0.626  -0.423  -0.470  -0.296  -0.908  -0.949  -0.748
76    P         1.192   1.219   1.298   1.404   1.439   1.550   1.264   1.300   1.419
77    A        -0.913  -0.844  -0.662  -0.942  -0.824  -0.594  -1.137  -1.034  -0.788
78    K         0.459   0.567   0.205   0.351   0.488   0.021   0.464   0.617   0.026
79    L        -0.095  -0.064   0.061  -0.066  -0.026   0.101  -0.451  -0.403  -0.235
80    W         1.192   1.219   1.298   1.410   1.448   1.555   1.264   1.300   1.419
81    E         0.459   0.337   0.184   0.115  -0.019  -0.173   0.464   0.278  -0.012
82    R         0.098   0.090   0.085  -0.007  -0.031  -0.126  -0.108  -0.128  -0.191
83    I         0.459   0.595   0.205   0.715   0.871   0.350   0.464   0.655   0.025
84    K        -0.095  -0.022   0.074  -0.453  -0.333  -0.192  -0.451  -0.326  -0.211
85    L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
86    S         1.192   1.219   1.298   1.208   1.256   1.372   1.264   1.300   1.419
87    K         0.459   0.347   0.186   0.372   0.251   0.046   0.464   0.293  -0.009
88    N         1.192   1.219   1.298   1.293   1.335   1.449   1.264   1.300   1.419
89    Y         1.192   1.219   1.298   1.346   1.386   1.497   1.264   1.300   1.419
90    T        -1.842  -1.732  -1.568  -1.585  -1.453  -1.279  -1.595  -1.468  -1.231
91    K        -0.239  -0.377  -0.564  -0.329  -0.534  -0.892  -0.222  -0.401  -0.659
92    A         1.192   1.219   1.298   1.199   1.238   1.364   1.264   1.300   1.419
93    L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
94    Q        -1.842  -1.687  -1.561  -2.043  -1.861  -1.621  -1.595  -1.445  -1.227
95    Q         1.192   1.219   1.298   1.304   1.340   1.459   1.264   1.300   1.419
96    I         1.192   1.219   1.298   1.314   1.348   1.468   1.264   1.300   1.419
97    D         0.459   0.347   0.186   0.426   0.271  -0.067   0.464   0.293  -0.009
98    E        -1.168  -1.181  -1.134  -1.443  -1.451  -1.271  -1.137  -1.145  -1.029
99    H        -0.559  -0.677  -0.617  -0.249  -0.418  -0.414  -0.680  -0.818  -0.736
100   L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
101   L        -1.168  -1.114  -1.129  -1.073  -0.993  -1.078  -1.137  -1.074  -1.024
102   H         0.459   0.543   0.199   0.771   0.873   0.430   0.464   0.583   0.014
103   W         0.459   0.347   0.186   0.836   0.713   0.468   0.464   0.293  -0.009
104   S        -1.377  -1.296  -1.162  -1.076  -0.954  -0.807  -1.366  -1.269  -1.056
105   K        -0.239  -0.385  -0.564  -0.301  -0.486  -0.822  -0.222  -0.413  -0.659
106   F         0.459   0.337   0.184   0.820   0.666   0.384   0.464   0.278  -0.012
107   F        -0.896  -0.869  -1.094  -0.568  -0.545  -0.823  -0.794  -0.762  -0.983
108   R        -0.896  -0.968  -1.110  -0.480  -0.590  -0.871  -0.794  -0.871  -1.000
109   H         0.459   0.442   0.192   0.797   0.781   0.365   0.464   0.438   0.003
110   K         0.459   0.337   0.184   0.351   0.208  -0.013   0.464   0.278  -0.012
111   C         1.192   1.219   1.298   1.424   1.461   1.568   1.264   1.300   1.419
112   K         1.192   1.219   1.298   0.961   1.005   1.148   1.264   1.300   1.419
113   Q         1.192   1.219   1.298   1.304   1.340   1.459   1.264   1.300   1.419
114   R         1.192   1.219   1.298   1.163   1.200   1.331   1.264   1.300   1.419
115   F        -0.703  -0.538  -0.602  -0.568  -0.381  -0.393  -0.908  -0.690  -0.717
116   T         1.192   1.219   1.298   1.333   1.371   1.486   1.264   1.300   1.419
117   K        -0.095   0.017   0.089  -0.380  -0.169  -0.117  -0.451  -0.258  -0.184
118   L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
119   T         0.459   0.347   0.186   0.734   0.602   0.334   0.464   0.293  -0.009
120   Q         1.192   1.219   1.298   1.304   1.340   1.459   1.264   1.300   1.419
121   V         0.459   0.337   0.184   0.656   0.526   0.294   0.464   0.278  -0.012
122   M        -0.559  -0.570  -0.600  -0.381  -0.389  -0.457  -0.680  -0.664  -0.709
123   I        -0.896  -1.123  -1.131  -0.448  -0.761  -0.841  -0.794  -1.045  -1.022
124   T        -0.896  -1.123  -1.131  -0.503  -0.851  -0.980  -0.794  -1.045  -1.022
125   E        -0.239  -0.468  -0.575  -0.455  -0.718  -0.788  -0.222  -0.522  -0.674
126   R         1.192   1.219   1.298   1.163   1.200   1.331   1.264   1.300   1.419
127   R         0.459   0.347   0.186   0.525   0.377   0.085   0.464   0.293  -0.009
128   L         0.459   0.442   0.192   0.555   0.538   0.214   0.464   0.438   0.003
129   A         1.192   1.219   1.298   1.199   1.238   1.364   1.264   1.300   1.419
130   L        -0.559  -0.623  -0.613  -0.422  -0.500  -0.490  -0.680  -0.740  -0.729
131   R        -1.168  -1.220  -1.144  -1.219  -1.402  -1.303  -1.137  -1.192  -1.039
132   E         0.459   0.337   0.184   0.134   0.008  -0.123   0.464   0.278  -0.012
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
135   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
136   E        -1.677  -1.598  -1.551  -1.733  -1.622  -1.451  -1.424  -1.337  -1.216
137   E        -0.239  -0.385  -0.564  -0.498  -0.670  -0.877  -0.222  -0.413  -0.659
138   R        -0.896  -1.123  -1.131  -0.596  -0.903  -0.947  -0.794  -1.045  -1.022
139   H        -0.239  -0.468  -0.575   0.204  -0.105  -0.358  -0.222  -0.522  -0.674
140   Y        -0.239  -0.468  -0.575   0.141  -0.160  -0.397  -0.222  -0.522  -0.674
141   V        -0.239  -0.468  -0.575   0.092  -0.176  -0.348  -0.222  -0.522  -0.674
142   G        -0.239  -0.468  -0.575   0.113  -0.190  -0.421  -0.222  -0.522  -0.674
143   V        -0.559  -0.665  -0.618  -0.333  -0.452  -0.407  -0.680  -0.802  -0.736
144   A        -0.095  -0.059   0.065  -0.346  -0.291  -0.146  -0.451  -0.394  -0.227
145   P        -0.239  -0.038  -0.523   0.250   0.482  -0.154  -0.222   0.042  -0.604
146   K         1.192   1.219   1.298   0.961   1.005   1.148   1.264   1.300   1.419
147   V         0.459   0.337   0.184   0.650   0.517   0.278   0.464   0.278  -0.012
148   K         0.459   0.337   0.184   0.356   0.216   0.002   0.464   0.278  -0.012
149   R         0.098  -0.015   0.069   0.141  -0.022   0.097  -0.108  -0.315  -0.220
150   R         1.192   1.219   1.298   1.163   1.200   1.331   1.264   1.300   1.419
151   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
152   Q        -0.831  -0.804  -0.662  -1.229  -1.185  -0.907  -1.023  -0.984  -0.789
153   N        -0.896  -1.123  -1.131  -0.463  -0.768  -0.846  -0.794  -1.045  -1.022
154   R         1.192   1.219   1.298   1.163   1.200   1.331   1.264   1.300   1.419
155   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
156   R         1.192   1.219   1.298   1.163   1.200   1.331   1.264   1.300   1.419
157   K         1.192   1.219   1.298   0.961   1.005   1.148   1.264   1.300   1.419
158   A         1.192   1.219   1.298   1.199   1.238   1.364   1.264   1.300   1.419
159   L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
160   V        -1.168  -1.096  -1.139  -0.927  -0.860  -0.904  -1.137  -1.081  -1.034
161   A         1.192   1.219   1.298   1.199   1.238   1.364   1.264   1.300   1.419
162   A         1.192   1.219   1.298   1.199   1.238   1.364   1.264   1.300   1.419
163   K         1.192   1.219   1.298   0.961   1.005   1.148   1.264   1.300   1.419
164   I        -0.559  -0.671  -0.630  -0.363  -0.574  -0.539  -0.680  -0.838  -0.752
165   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
166   K         0.459   0.347   0.186   0.351   0.221  -0.011   0.464   0.293  -0.009
167   A        -0.896  -1.024  -1.116  -0.536  -0.697  -0.853  -0.794  -0.941  -1.007
168   I         1.192   1.219   1.298   1.314   1.348   1.468   1.264   1.300   1.419
169   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
170   K         0.459   0.347   0.186   0.351   0.221  -0.011   0.464   0.293  -0.009
171   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
172   L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
173   M        -0.239  -0.296  -0.556  -0.011  -0.089  -0.413  -0.222  -0.301  -0.649
174   D        -0.703  -0.754  -0.624  -1.252  -1.311  -1.092  -0.908  -0.936  -0.746
175   R         1.192   1.219   1.298   1.163   1.200   1.331   1.264   1.300   1.419
176   L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
177   K         0.459   0.347   0.186   0.351   0.221  -0.011   0.464   0.293  -0.009
178   S         0.459   0.347   0.186   0.618   0.500   0.253   0.464   0.293  -0.009
179   G         1.192   1.219   1.298   1.318   1.355   1.472   1.264   1.300   1.419
180   A        -0.559  -0.665  -0.618  -0.399  -0.520  -0.472  -0.680  -0.802  -0.736
181   Y         1.192   1.219   1.298   1.346   1.386   1.497   1.264   1.300   1.419
182   G         1.192   1.219   1.298   1.318   1.355   1.472   1.264   1.300   1.419
183   D         0.459   0.442   0.192   0.426   0.410  -0.052   0.464   0.438   0.003
184   K        -0.559  -0.671  -0.630  -0.623  -0.762  -0.656  -0.680  -0.838  -0.752
185   P         1.192   1.219   1.298   1.404   1.439   1.550   1.264   1.300   1.419
186   L         0.459   0.574   0.205   0.572   0.699   0.276   0.464   0.626   0.025
187   N         1.192   1.219   1.298   1.293   1.335   1.449   1.264   1.300   1.419
188   V         0.459   0.347   0.186   0.668   0.553   0.326   0.464   0.293  -0.009
189   D        -0.239  -0.468  -0.575  -0.083  -0.360  -0.539  -0.222  -0.522  -0.674
190   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
191   K        -1.168  -1.259  -1.139  -1.275  -1.427  -1.293  -1.137  -1.199  -1.031
192   V        -0.095  -0.092   0.055  -0.100  -0.110   0.075  -0.451  -0.455  -0.246
193   W         1.192   1.219   1.298   1.410   1.448   1.555   1.264   1.300   1.419
194   K         0.459   0.337   0.184   0.371   0.237   0.040   0.464   0.278  -0.012
195   K         1.192   1.219   1.298   0.961   1.005   1.148   1.264   1.300   1.419
196   I         0.459   0.543   0.199   0.652   0.761   0.305   0.464   0.583   0.014
197   M        -0.156  -0.094   0.064  -0.210  -0.143   0.085  -0.565  -0.458  -0.229
198   G        -0.896  -1.123  -1.131  -0.536  -0.869  -1.029  -0.794  -1.045  -1.022
199   Q        -2.179  -2.060  -1.896  -1.835  -1.649  -1.443  -1.709  -1.587  -1.345
200   M        -1.168  -1.213  -1.142  -0.934  -1.017  -0.921  -1.137  -1.174  -1.037
201   E        -0.559  -0.358  -0.564  -1.031  -0.733  -1.031  -0.680  -0.400  -0.662
202   E        -1.715  -1.676  -1.556  -1.659  -1.604  -1.513  -1.480  -1.430  -1.222
203   E        -0.239  -0.385  -0.564  -0.510  -0.695  -0.906  -0.222  -0.413  -0.659
204   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
205   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
206   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
207   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
208   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
209   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
210   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
211   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
212   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
213   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
214   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
215   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   N        -1.715  -1.653  -1.548  -1.620  -1.561  -1.431  -1.480  -1.409  -1.216
218   S        -1.715  -1.548  -1.533  -1.930  -1.612  -1.670  -1.480  -1.293  -1.202
219   Q        -0.559  -0.363  -0.578  -0.910  -0.651  -0.881  -0.680  -0.413  -0.681
220   D        -0.703  -0.771  -0.625  -1.165  -1.177  -0.905  -0.908  -0.961  -0.747
221   E         0.459   0.567   0.205   0.082   0.220  -0.229   0.464   0.617   0.026
222   E         0.459   0.442   0.192   0.082   0.071  -0.249   0.464   0.438   0.003
223   E        -0.559  -0.463  -0.596  -0.957  -0.845  -0.932  -0.680  -0.569  -0.708
224   D        -0.136  -0.060   0.068  -0.788  -0.675  -0.442  -0.528  -0.396  -0.221
225   W        -1.292  -1.188  -1.158  -1.218  -1.209  -1.113  -1.275  -1.168  -1.052
226   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
227   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
228   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
229   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
230   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
231   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
232   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
233   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
234   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
235   D        -0.136  -0.063   0.065  -0.788  -0.679  -0.444  -0.528  -0.401  -0.227
236   E        -0.357  -0.421  -0.584  -0.653  -0.748  -0.920  -0.379  -0.477  -0.687
237   E        -0.136  -0.086   0.061  -0.788  -0.714  -0.448  -0.528  -0.445  -0.235
238   E         0.098   0.237   0.141  -0.415  -0.203  -0.330  -0.108   0.119  -0.088
239   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
240   S        -0.896  -1.123  -1.131  -0.651  -0.973  -1.122  -0.794  -1.045  -1.022
241   D        -0.095  -0.115   0.055  -0.574  -0.695  -0.437  -0.451  -0.499  -0.246
242   D        -1.377  -1.334  -1.156  -1.686  -1.615  -1.303  -1.366  -1.293  -1.051
243   G         0.459   0.337   0.184   0.713   0.564   0.304   0.464   0.278  -0.012
244   E         0.459   0.347   0.186   0.114  -0.008  -0.176   0.464   0.293  -0.009
245   V         0.459   0.337   0.184   0.627   0.483   0.217   0.464   0.278  -0.012
246   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
247   Y         0.098   0.094   0.086   0.318   0.313   0.261  -0.108  -0.122  -0.188
248   V         1.192   1.219   1.298   1.240   1.286   1.401   1.264   1.300   1.419
249   A        -0.559  -0.595  -0.624  -0.930  -0.979  -0.923  -0.680  -0.759  -0.744
250   D         1.192   1.219   1.298   1.099   1.144   1.274   1.264   1.300   1.419
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   D        -0.559  -0.541  -0.609  -0.738  -0.787  -0.904  -0.680  -0.682  -0.725
253   G        -1.168  -1.161  -1.144  -1.118  -1.256  -1.233  -1.137  -1.141  -1.039
254   E        -0.703  -0.718  -0.616  -1.074  -1.000  -0.863  -0.908  -0.883  -0.734
255   G        -0.896  -0.869  -1.094  -0.752  -0.761  -1.122  -0.794  -0.762  -0.983
256   E         0.098   0.030   0.077  -0.415  -0.520  -0.425  -0.108  -0.233  -0.206
257   Y        -1.225  -1.110  -1.155  -0.887  -0.739  -0.776  -1.175  -1.029  -1.047
258   V         0.316   0.386   0.139   0.427   0.521   0.125   0.248   0.353  -0.092
259   D        -0.095  -0.115   0.055  -0.574  -0.695  -0.437  -0.451  -0.499  -0.246
260   V        -1.250  -1.241  -1.137  -0.980  -0.977  -0.838  -1.252  -1.211  -1.032
261   D        -0.896  -1.048  -1.120  -1.080  -1.259  -1.311  -0.794  -0.966  -1.011
262   D         1.192   1.219   1.298   1.099   1.144   1.274   1.264   1.300   1.419
263   L        -0.239  -0.265  -0.542  -0.030  -0.066  -0.437  -0.222  -0.262  -0.630
264   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
265   K        -0.559  -0.571  -0.621  -0.703  -0.768  -0.766  -0.680  -0.734  -0.741
266   W         1.192   1.219   1.298   1.410   1.448   1.555   1.264   1.300   1.419
267   L         1.192   1.219   1.298   1.143   1.176   1.313   1.264   1.300   1.419
268   A        -0.239  -0.061  -0.522   0.101   0.322  -0.356  -0.222   0.013  -0.603
269   D        -0.831  -0.848  -0.670  -0.877  -0.900  -0.652  -1.023  -1.042  -0.799
270   S        -0.559  -0.571  -0.621  -0.464  -0.541  -0.590  -0.680  -0.734  -0.741
271   D        -1.250  -1.235  -1.137  -1.157  -1.117  -0.966  -1.252  -1.212  -1.033
272   R        -1.395  -1.372  -1.161  -1.757  -1.710  -1.392  -1.379  -1.330  -1.055
273   E        -0.496  -0.609  -0.607  -0.794  -0.926  -0.861  -0.565  -0.713  -0.716
274   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
275   A        -1.395  -1.302  -1.154  -1.608  -1.493  -1.232  -1.379  -1.267  -1.048
276   S        -1.823  -1.827  -1.571  -1.679  -1.714  -1.411  -1.574  -1.543  -1.234
277   S        -0.667  -0.615  -0.617  -0.673  -0.603  -0.594  -0.827  -0.761  -0.735
278   A        -1.677  -1.519  -1.531  -1.756  -1.590  -1.473  -1.424  -1.254  -1.199
279   S        -0.239  -0.377  -0.564   0.014  -0.153  -0.464  -0.222  -0.401  -0.659
280   E        -1.438  -1.332  -1.171  -1.741  -1.624  -1.354  -1.424  -1.302  -1.065
281   S        -0.667  -0.641  -0.636  -0.860  -0.954  -0.937  -0.827  -0.829  -0.760
282   E        -0.667  -0.606  -0.621  -1.108  -1.027  -0.976  -0.827  -0.759  -0.740
283   S        -0.831  -0.765  -0.656  -1.145  -1.056  -0.959  -1.023  -0.928  -0.781
284   D        -0.559  -0.605  -0.617  -0.487  -0.552  -0.628  -0.680  -0.735  -0.736
285   S        -0.703  -0.625  -0.617  -0.888  -0.765  -0.814  -0.908  -0.819  -0.738
286   E         0.098   0.098   0.089  -0.415  -0.414  -0.409  -0.108  -0.115  -0.183
287   S        -0.913  -0.875  -0.665  -1.400  -1.274  -0.967  -1.137  -1.073  -0.792
288   E        -0.156  -0.086   0.073  -0.691  -0.625  -0.361  -0.565  -0.444  -0.213
289   S        -0.896  -0.930  -1.097  -0.543  -0.571  -0.850  -0.794  -0.831  -0.986
290   D         0.459   0.590   0.212   0.496   0.659   0.167   0.464   0.649   0.037
291   S        -1.292  -1.217  -1.141  -1.574  -1.454  -1.277  -1.275  -1.184  -1.036
292   D         0.028   0.022   0.075  -0.286  -0.320  -0.341  -0.229  -0.249  -0.209
293   S        -0.117  -0.109   0.055  -0.516  -0.553  -0.323  -0.492  -0.487  -0.246
294   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
295   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
296   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
297   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
298   K        -0.703  -0.639  -0.619  -1.252  -1.097  -1.043  -0.908  -0.830  -0.739
299   N        -1.505  -1.466  -1.527  -1.151  -1.106  -1.336  -1.252  -1.203  -1.195
300   S        -1.505  -1.220  -1.497  -1.251  -0.908  -1.196  -1.252  -0.939  -1.169
301   A        -1.715  -1.775  -1.565  -1.381  -1.467  -1.225  -1.480  -1.502  -1.229
302   K        -0.239  -0.038  -0.523  -0.244   0.006  -0.625  -0.222   0.042  -0.604
303   R        -1.250  -1.350  -1.154  -1.276  -1.355  -1.068  -1.252  -1.309  -1.049
304   R        -0.559  -0.469  -0.600  -0.561  -0.472  -0.661  -0.680  -0.579  -0.713
305   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
306   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
307   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
308   K         1.192   1.219   1.298   0.961   1.005   1.148   1.264   1.300   1.419
309   -        -0.860  -0.760  -0.648  -0.931  -0.791  -0.638  -1.078  -0.944  -0.773
310   -        -0.860  -0.760  -0.648  -1.266  -1.108  -1.003  -1.078  -0.944  -0.773
311   -        -1.399  -1.380  -1.170  -1.247  -1.220  -0.965  -1.370  -1.333  -1.063
312   -         0.219   0.187   0.140   0.220   0.185   0.102   0.093   0.036  -0.090
313   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
314   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
315   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
316   -        -1.399  -1.340  -1.161  -1.608  -1.498  -1.315  -1.370  -1.289  -1.054
317   K        -0.357  -0.539  -0.593  -0.382  -0.615  -0.700  -0.379  -0.618  -0.698
318   G        -2.208  -2.183  -1.913  -1.795  -1.775  -1.440  -1.723  -1.672  -1.356
319   T        -0.046   0.075   0.109  -0.291  -0.109  -0.052  -0.362  -0.155  -0.146
320   S        -2.516  -2.376  -2.176  -1.956  -1.742  -1.559  -1.823  -1.693  -1.428
321   A        -0.896  -0.852  -1.096  -0.798  -0.756  -1.051  -0.794  -0.744  -0.985
322   K        -1.168  -1.084  -1.113  -1.239  -1.105  -1.152  -1.137  -1.015  -1.005
323   T        -1.250  -1.123  -1.128  -1.303  -1.141  -1.081  -1.252  -1.112  -1.024
324   K        -0.095  -0.092   0.055  -0.380  -0.402  -0.207  -0.451  -0.455  -0.246
325   R        -1.505  -1.613  -1.548  -1.148  -1.344  -1.252  -1.252  -1.348  -1.214
326   P         0.459   0.347   0.186   0.766   0.616   0.293   0.464   0.293  -0.009
327   K        -1.505  -1.631  -1.548  -1.445  -1.645  -1.550  -1.252  -1.363  -1.213
328   V        -0.095  -0.105   0.054  -0.126  -0.146   0.072  -0.451  -0.479  -0.248
329   E         0.459   0.337   0.184   0.134   0.008  -0.123   0.464   0.278  -0.012
330   I         0.098   0.030   0.077   0.228   0.111   0.122  -0.108  -0.233  -0.206
331   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
332   Y         0.459   0.347   0.186   0.771   0.650   0.410   0.464   0.293  -0.009
333   E         1.192   1.219   1.298   0.705   0.747   0.916   1.264   1.300   1.419
334   E        -0.703  -0.748  -0.626  -0.891  -0.915  -0.761  -0.908  -0.929  -0.748
335   E         0.098   0.030   0.077  -0.415  -0.520  -0.425  -0.108  -0.233  -0.206
336   H        -1.715  -1.548  -1.533  -1.696  -1.399  -1.390  -1.480  -1.293  -1.202
337   E        -1.677  -1.520  -1.538  -1.733  -1.540  -1.455  -1.424  -1.252  -1.205
338   V        -1.844  -1.736  -1.573  -1.876  -1.734  -1.436  -1.582  -1.464  -1.235
339   Q        -1.844  -1.810  -1.580  -1.705  -1.786  -1.431  -1.582  -1.528  -1.240
340   N        -1.844  -1.755  -1.572  -2.014  -1.943  -1.576  -1.582  -1.480  -1.234
341   A        -0.860  -0.788  -0.651  -0.883  -0.774  -0.600  -1.078  -0.974  -0.777
342   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   E        -2.179  -2.112  -1.891  -2.041  -2.042  -1.655  -1.709  -1.624  -1.342
344   Q        -1.168  -1.259  -1.139  -0.879  -1.012  -0.921  -1.137  -1.199  -1.031
345   E        -1.715  -1.799  -1.569  -1.741  -1.794  -1.418  -1.480  -1.515  -1.232
346   V        -1.842  -1.794  -1.565  -1.532  -1.456  -1.179  -1.595  -1.522  -1.229
347   A        -0.239  -0.385  -0.564  -0.016  -0.201  -0.520  -0.222  -0.413  -0.659
348   Q        -2.179  -2.050  -1.892  -1.513  -1.329  -1.183  -1.709  -1.580  -1.343
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P10962
Output conservation file - output/P10962
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
