1     M         1.134   1.159   1.182   1.358   1.398   1.416   1.184   1.225   1.254
2     R         0.044  -0.224  -0.205   0.490   0.042   0.057  -0.006  -0.444  -0.417
3     S        -1.163  -0.879  -1.001  -1.362  -0.971  -1.044  -1.195  -0.855  -0.965
4     L        -1.163  -1.108  -1.047  -1.321  -1.303  -1.173  -1.195  -1.108  -1.018
5     N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     T         0.044  -0.224  -0.205   0.055  -0.378  -0.355  -0.006  -0.444  -0.417
7     L        -1.163  -1.108  -1.047  -1.404  -1.343  -1.238  -1.195  -1.108  -1.018
8     L        -1.163  -1.108  -1.047  -1.443  -1.404  -1.271  -1.195  -1.108  -1.018
9     L        -1.163  -1.108  -1.047  -0.983  -1.031  -0.900  -1.195  -1.108  -1.018
10    S        -1.163  -1.108  -1.047  -1.537  -1.464  -1.332  -1.195  -1.108  -1.018
11    L        -1.163  -1.108  -1.047  -1.253  -1.235  -1.116  -1.195  -1.108  -1.018
12    F         1.134   1.159   1.182   1.286   1.332   1.351   1.184   1.225   1.254
13    V        -1.163  -1.108  -1.047  -1.527  -1.390  -1.297  -1.195  -1.108  -1.018
14    A         0.044  -0.224  -0.205   0.011  -0.442  -0.440  -0.006  -0.444  -0.417
15    M        -1.163  -1.108  -1.047  -1.428  -1.204  -1.141  -1.195  -1.108  -1.018
16    S         0.044  -0.224  -0.205  -0.122  -0.590  -0.539  -0.006  -0.444  -0.417
17    S         0.044  -0.224  -0.205   0.403  -0.142  -0.138  -0.006  -0.444  -0.417
18    G         0.044  -0.224  -0.205   0.315  -0.205  -0.194  -0.006  -0.444  -0.417
19    A        -1.163  -1.108  -1.047  -1.367  -1.313  -1.196  -1.195  -1.108  -1.018
20    P        -1.766  -1.550  -1.630  -1.497  -1.219  -1.369  -1.492  -1.275  -1.302
21    L         1.134   1.159   1.182   0.946   0.998   1.045   1.184   1.225   1.254
22    L        -0.331  -0.121  -0.177  -0.592  -0.265  -0.332  -0.600  -0.274  -0.372
23    K        -1.163  -1.108  -1.047  -1.130  -1.018  -0.923  -1.195  -1.108  -1.018
24    I         0.044  -0.224  -0.205   0.252  -0.222  -0.218  -0.006  -0.444  -0.417
25    R         1.134   1.159   1.182   1.360   1.389   1.417   1.184   1.225   1.254
26    E        -1.163  -1.108  -1.047  -1.184  -1.067  -0.966  -1.195  -1.108  -1.018
27    E         0.044  -0.224  -0.205   0.005  -0.394  -0.321  -0.006  -0.444  -0.417
28    K        -0.331  -0.121  -0.177  -0.361   0.006  -0.121  -0.600  -0.274  -0.372
29    -        -1.130  -1.007  -1.047  -1.353  -1.162  -1.222  -1.139  -0.986  -1.018
30    -        -0.375  -0.279  -0.224  -0.699  -0.536  -0.437  -0.675  -0.536  -0.450
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -0.375  -0.279  -0.224  -0.608  -0.452  -0.355  -0.675  -0.536  -0.450
35    -        -0.375  -0.279  -0.224  -0.395  -0.246  -0.163  -0.675  -0.536  -0.450
36    N         1.134   1.159   1.182   1.167   1.225   1.244   1.184   1.225   1.254
37    S        -0.755  -1.001  -1.028  -0.738  -1.100  -1.126  -0.675  -0.979  -0.997
38    S        -1.068  -1.006  -1.000  -1.267  -1.091  -1.065  -1.088  -0.985  -0.963
39    L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
40    P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
41    S        -0.755  -1.001  -1.028  -0.556  -0.939  -1.004  -0.675  -0.979  -0.997
42    I         0.153   0.004  -0.143   0.181  -0.017  -0.273   0.151  -0.077  -0.316
43    K        -0.252  -0.279  -0.223  -0.310  -0.349  -0.253  -0.468  -0.536  -0.449
44    I        -0.252  -0.003  -0.134  -0.439  -0.016  -0.247  -0.468  -0.089  -0.301
45    F         1.134   1.159   1.182   1.285   1.325   1.350   1.184   1.225   1.254
46    G        -0.252  -0.279  -0.223  -0.561  -0.633  -0.525  -0.468  -0.536  -0.449
47    T         0.153   0.004  -0.143   0.471   0.252  -0.027   0.151  -0.077  -0.316
48    G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
49    G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
50    T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
51    I         1.134   1.159   1.182   1.095   1.148   1.179   1.184   1.225   1.254
52    A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
53    S        -0.252  -0.279  -0.223  -0.545  -0.632  -0.518  -0.468  -0.536  -0.449
54    K        -1.258  -0.995  -1.023  -1.031  -0.683  -0.711  -1.294  -0.972  -0.990
55    G        -0.252  -0.279  -0.223  -0.561  -0.633  -0.525  -0.468  -0.536  -0.449
56    S        -1.068  -1.006  -1.000  -1.205  -1.090  -1.073  -1.088  -0.985  -0.963
57    T        -0.252  -0.279  -0.223  -0.497  -0.542  -0.439  -0.468  -0.536  -0.449
58    S         0.153  -0.024  -0.137   0.130  -0.106  -0.279   0.151  -0.121  -0.306
59    A        -1.761  -1.717  -1.630  -1.968  -1.921  -1.771  -1.501  -1.416  -1.302
60    T        -0.755  -1.001  -1.028  -0.402  -0.797  -0.833  -0.675  -0.979  -0.997
61    T        -0.252  -0.003  -0.134  -0.398   0.017  -0.210  -0.468  -0.089  -0.301
62    A        -0.252  -0.279  -0.223  -0.497  -0.580  -0.488  -0.468  -0.536  -0.449
63    G        -1.258  -0.995  -1.023  -1.364  -1.013  -1.022  -1.294  -0.972  -0.990
64    Y         1.134   1.159   1.182   1.269   1.304   1.336   1.184   1.225   1.254
65    S        -1.761  -1.717  -1.630  -1.850  -1.743  -1.606  -1.501  -1.416  -1.302
66    V        -1.258  -0.995  -1.023  -1.456  -1.032  -1.085  -1.294  -0.972  -0.990
67    G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
68    -         1.134   1.159   1.182   1.017   1.069   1.109   1.184   1.225   1.254
69    L        -0.252  -0.279  -0.223  -0.518  -0.616  -0.520  -0.468  -0.536  -0.449
70    T        -0.252  -0.279  -0.223  -0.486  -0.538  -0.432  -0.468  -0.536  -0.449
71    V        -0.252  -0.279  -0.223  -0.439  -0.507  -0.419  -0.468  -0.536  -0.449
72    N        -1.761  -1.717  -1.630  -1.651  -1.556  -1.420  -1.501  -1.416  -1.302
73    D        -1.258  -0.995  -1.023  -1.231  -0.824  -0.871  -1.294  -0.972  -0.990
74    L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
75    I        -0.375  -0.279  -0.224  -0.680  -0.506  -0.420  -0.675  -0.535  -0.450
76    E        -0.252  -0.007  -0.135  -0.169   0.183  -0.003  -0.468  -0.095  -0.302
77    A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
78    V         0.153  -0.024  -0.137   0.181  -0.061  -0.262   0.151  -0.121  -0.306
79    P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
80    S        -0.252  -0.279  -0.223  -0.566  -0.637  -0.533  -0.468  -0.536  -0.449
81    L        -0.252  -0.279  -0.223  -0.497  -0.602  -0.505  -0.468  -0.536  -0.449
82    A        -0.755  -1.001  -1.028  -0.455  -0.876  -0.938  -0.675  -0.979  -0.997
83    E        -1.761  -1.717  -1.630  -1.692  -1.563  -1.424  -1.501  -1.416  -1.302
84    K        -1.761  -1.717  -1.630  -1.621  -1.552  -1.423  -1.501  -1.416  -1.302
85    A        -0.252  -0.007  -0.135  -0.566  -0.144  -0.364  -0.468  -0.095  -0.302
86    N         0.153  -0.024  -0.137   0.354   0.143  -0.026   0.151  -0.121  -0.306
87    L        -0.252  -0.279  -0.223  -0.497  -0.602  -0.505  -0.468  -0.536  -0.449
88    D        -1.258  -0.995  -1.023  -1.157  -0.768  -0.811  -1.294  -0.972  -0.990
89    Y        -0.252  -0.279  -0.223  -0.420  -0.441  -0.335  -0.468  -0.536  -0.449
90    L        -0.252  -0.279  -0.223  -0.518  -0.616  -0.520  -0.468  -0.536  -0.449
91    Q         1.134   1.159   1.182   1.369   1.392   1.425   1.184   1.225   1.254
92    V         1.134   1.159   1.182   1.073   1.129   1.159   1.184   1.225   1.254
93    S        -0.755  -1.001  -1.028  -0.677  -1.112  -1.187  -0.675  -0.979  -0.997
94    N         1.134   1.159   1.182   1.179   1.235   1.254   1.184   1.225   1.254
95    V        -0.252  -0.003  -0.134  -0.326   0.053  -0.137  -0.468  -0.089  -0.301
96    G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
97    S         1.134   1.159   1.182   1.005   1.053   1.098   1.184   1.225   1.254
98    N        -0.755  -1.001  -1.028  -0.410  -0.807  -0.850  -0.675  -0.979  -0.997
99    S        -1.761  -1.717  -1.630  -1.700  -1.732  -1.582  -1.501  -1.416  -1.302
100   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
101   N        -0.252  -0.279  -0.223  -0.359  -0.408  -0.325  -0.468  -0.536  -0.449
102   Y        -0.755  -1.001  -1.028  -0.483  -0.893  -0.960  -0.675  -0.979  -0.997
103   T        -0.755  -1.001  -1.028  -0.779  -1.169  -1.210  -0.675  -0.979  -0.997
104   H        -1.258  -0.995  -1.023  -1.116  -0.680  -0.753  -1.294  -0.972  -0.990
105   L        -0.252  -0.279  -0.223  -0.518  -0.616  -0.520  -0.468  -0.536  -0.449
106   I         0.153   0.004  -0.143   0.056  -0.143  -0.375   0.151  -0.077  -0.316
107   P        -1.068  -0.991  -1.004  -0.933  -0.787  -0.823  -1.088  -0.966  -0.967
108   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
109   Y        -1.258  -0.995  -1.023  -1.414  -0.933  -1.015  -1.294  -0.972  -0.990
110   H        -1.761  -1.717  -1.630  -1.417  -1.398  -1.258  -1.501  -1.416  -1.302
111   G        -0.755  -1.001  -1.028  -0.857  -1.269  -1.309  -0.675  -0.979  -0.997
112   I         1.134   1.159   1.182   1.095   1.148   1.179   1.184   1.225   1.254
113   S        -0.755  -1.001  -1.028  -0.825  -1.210  -1.242  -0.675  -0.979  -0.997
114   E        -0.252  -0.279  -0.223  -0.431  -0.447  -0.336  -0.468  -0.536  -0.449
115   A        -0.252  -0.279  -0.223  -0.296  -0.448  -0.345  -0.468  -0.536  -0.449
116   L        -0.755  -1.001  -1.028  -0.674  -1.048  -1.102  -0.675  -0.979  -0.997
117   A         1.134   1.159   1.182   0.987   1.042   1.082   1.184   1.225   1.254
118   S        -0.755  -1.001  -1.028  -0.455  -0.876  -0.938  -0.675  -0.979  -0.997
119   D        -0.755  -1.001  -1.028  -0.479  -0.892  -0.950  -0.675  -0.979  -0.997
120   D        -0.375  -0.279  -0.224  -0.469  -0.317  -0.230  -0.675  -0.536  -0.450
121   Y        -0.755  -1.001  -1.028  -0.642  -0.999  -1.037  -0.675  -0.979  -0.997
122   A        -0.755  -1.001  -1.028  -0.319  -0.761  -0.849  -0.675  -0.979  -0.997
123   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
124   A        -0.252  -0.279  -0.223  -0.476  -0.566  -0.473  -0.468  -0.536  -0.449
125   V         1.134   1.159   1.182   1.073   1.129   1.159   1.184   1.225   1.254
126   V        -0.252  -0.003  -0.134  -0.449  -0.029  -0.256  -0.468  -0.089  -0.301
127   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
128   H         1.134   1.159   1.182   1.430   1.452   1.480   1.184   1.225   1.254
129   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
130   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
131   D         1.134   1.159   1.182   1.277   1.302   1.343   1.184   1.225   1.254
132   T        -0.252  -0.279  -0.223  -0.497  -0.542  -0.439  -0.468  -0.536  -0.449
133   M        -0.755  -1.001  -1.028  -0.742  -1.067  -1.072  -0.675  -0.979  -0.997
134   E         1.134   1.159   1.182   1.288   1.304   1.353   1.184   1.225   1.254
135   E         1.134   1.159   1.182   1.288   1.304   1.353   1.184   1.225   1.254
136   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
137   A         0.153  -0.024  -0.137   0.083  -0.171  -0.369   0.151  -0.121  -0.306
138   F        -1.068  -0.864  -1.028  -0.859  -0.601  -0.841  -1.088  -0.866  -0.997
139   F         1.134   1.159   1.182   1.285   1.325   1.350   1.184   1.225   1.254
140   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
141   D         1.134   1.159   1.182   1.277   1.302   1.343   1.184   1.225   1.254
142   L        -0.252  -0.007  -0.135  -0.439  -0.075  -0.238  -0.468  -0.095  -0.302
143   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
144   I        -0.252  -0.007  -0.135  -0.439  -0.023  -0.249  -0.468  -0.095  -0.302
145   N        -1.068  -1.006  -1.000  -1.110  -0.948  -0.955  -1.088  -0.985  -0.963
146   S        -0.252  -0.279  -0.223  -0.439  -0.543  -0.443  -0.468  -0.536  -0.449
147   E        -1.761  -1.717  -1.630  -1.727  -1.595  -1.448  -1.501  -1.416  -1.302
148   K         0.153  -0.024  -0.137   0.364   0.072  -0.152   0.151  -0.121  -0.306
149   P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
150   V        -0.755  -1.001  -1.028  -0.705  -1.125  -1.199  -0.675  -0.979  -0.997
151   C         0.153   0.004  -0.143   0.260   0.097  -0.095   0.151  -0.077  -0.316
152   I        -0.252  -0.279  -0.223  -0.449  -0.506  -0.418  -0.468  -0.536  -0.449
153   A         0.153   0.004  -0.143   0.161  -0.048  -0.320   0.151  -0.077  -0.316
154   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
155   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
156   M         1.134   1.159   1.182   1.358   1.398   1.416   1.184   1.225   1.254
157   R         1.134   1.159   1.182   1.361   1.390   1.418   1.184   1.225   1.254
158   P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
159   A         0.153   0.004  -0.143   0.092  -0.124  -0.376   0.151  -0.077  -0.316
160   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
161   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
162   T         0.153   0.004  -0.143   0.210   0.010  -0.239   0.151  -0.077  -0.316
163   S        -0.252  -0.003  -0.134  -0.550  -0.133  -0.348  -0.468  -0.089  -0.301
164   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
165   D         1.134   1.159   1.182   1.277   1.302   1.343   1.184   1.225   1.254
166   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
167   P         0.153  -0.024  -0.137   0.337   0.058  -0.174   0.151  -0.121  -0.306
168   M         1.134   1.159   1.182   1.358   1.398   1.416   1.184   1.225   1.254
169   N         1.134   1.159   1.182   1.179   1.235   1.254   1.184   1.225   1.254
170   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
171   Y        -0.252  -0.279  -0.223  -0.482  -0.481  -0.378  -0.468  -0.536  -0.449
172   Q        -0.252  -0.279  -0.223  -0.226  -0.251  -0.166  -0.468  -0.536  -0.449
173   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
174   V         1.134   1.159   1.182   1.073   1.129   1.159   1.184   1.225   1.254
175   S        -1.761  -1.717  -1.630  -1.866  -1.753  -1.617  -1.501  -1.416  -1.302
176   I        -0.252  -0.279  -0.223  -0.449  -0.506  -0.418  -0.468  -0.536  -0.449
177   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
178   A        -0.375  -0.279  -0.224  -0.807  -0.637  -0.535  -0.675  -0.536  -0.450
179   S         1.134   1.159   1.182   1.005   1.053   1.098   1.184   1.225   1.254
180   E        -0.252  -0.279  -0.223  -0.263  -0.315  -0.220  -0.468  -0.536  -0.449
181   K        -1.761  -1.717  -1.630  -1.373  -1.365  -1.231  -1.501  -1.416  -1.302
182   S         1.134   1.159   1.182   1.005   1.053   1.098   1.184   1.225   1.254
183   L        -1.761  -1.717  -1.630  -1.611  -1.573  -1.447  -1.501  -1.416  -1.302
184   G         0.153  -0.024  -0.137   0.164  -0.077  -0.219   0.151  -0.121  -0.306
185   R         1.134   1.159   1.182   1.361   1.390   1.418   1.184   1.225   1.254
186   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
187   T         0.153  -0.024  -0.137   0.269   0.035  -0.143   0.151  -0.121  -0.306
188   M        -0.375  -0.279  -0.224  -0.573  -0.414  -0.322  -0.675  -0.536  -0.450
189   I        -0.375  -0.279  -0.224  -0.680  -0.507  -0.420  -0.675  -0.536  -0.450
190   T        -0.755  -1.001  -1.028  -0.807  -1.177  -1.206  -0.675  -0.979  -0.997
191   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
192   N         1.134   1.159   1.182   1.179   1.235   1.254   1.184   1.225   1.254
193   D         1.134   1.159   1.182   1.277   1.302   1.343   1.184   1.225   1.254
194   R         1.134   1.159   1.182   1.361   1.390   1.418   1.184   1.225   1.254
195   I         1.134   1.159   1.182   1.095   1.148   1.179   1.184   1.225   1.254
196   A        -0.252  -0.279  -0.223  -0.550  -0.634  -0.526  -0.468  -0.536  -0.449
197   S         1.134   1.159   1.182   1.005   1.053   1.098   1.184   1.225   1.254
198   G        -0.252  -0.279  -0.223  -0.561  -0.633  -0.525  -0.468  -0.536  -0.449
199   F         1.134   1.159   1.182   1.285   1.325   1.350   1.184   1.225   1.254
200   W        -0.252  -0.279  -0.223  -0.098  -0.133  -0.043  -0.468  -0.536  -0.449
201   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
202   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
203   K         1.134   1.159   1.182   1.285   1.315   1.350   1.184   1.225   1.254
204   M        -0.252  -0.279  -0.223  -0.276  -0.288  -0.204  -0.468  -0.536  -0.449
205   N         0.153  -0.024  -0.137   0.269   0.010  -0.215   0.151  -0.121  -0.306
206   A         0.153   0.004  -0.143   0.104  -0.119  -0.367   0.151  -0.077  -0.316
207   N         0.153  -0.024  -0.137   0.324   0.100  -0.090   0.151  -0.121  -0.306
208   S        -1.761  -1.717  -1.630  -1.669  -1.682  -1.547  -1.501  -1.416  -1.302
209   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
210   D         1.134   1.159   1.182   1.277   1.302   1.343   1.184   1.225   1.254
211   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
212   F         1.134   1.159   1.182   1.285   1.325   1.350   1.184   1.225   1.254
213   R        -0.252  -0.279  -0.223  -0.134  -0.196  -0.106  -0.468  -0.536  -0.449
214   A         0.153   0.004  -0.143   0.092  -0.124  -0.376   0.151  -0.077  -0.316
215   D        -0.755  -1.001  -1.028  -0.468  -0.888  -0.943  -0.675  -0.979  -0.997
216   E         1.134   1.159   1.182   1.288   1.304   1.353   1.184   1.225   1.254
217   Q        -0.252  -0.279  -0.223  -0.392  -0.381  -0.280  -0.468  -0.536  -0.449
218   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
219   Y        -1.258  -0.995  -1.023  -1.309  -0.868  -0.933  -1.294  -0.972  -0.990
220   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
221   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
222   Y        -1.761  -1.717  -1.630  -1.576  -1.518  -1.394  -1.501  -1.416  -1.302
223   F        -1.258  -0.995  -1.023  -1.376  -0.893  -0.982  -1.294  -0.972  -0.990
224   S        -0.755  -1.001  -1.028  -0.762  -1.106  -1.112  -0.675  -0.979  -0.997
225   N        -0.252  -0.007  -0.135  -0.268   0.117  -0.090  -0.468  -0.095  -0.302
226   D        -0.755  -1.001  -1.028  -0.335  -0.740  -0.803  -0.675  -0.979  -0.997
227   D        -1.761  -1.717  -1.630  -1.354  -1.298  -1.164  -1.501  -1.416  -1.302
228   V        -0.755  -1.001  -1.028  -0.509  -0.925  -1.013  -0.675  -0.979  -0.997
229   E        -1.258  -0.995  -1.023  -1.048  -0.704  -0.724  -1.294  -0.972  -0.990
230   F        -1.068  -1.006  -1.000  -0.825  -0.693  -0.683  -1.088  -0.985  -0.963
231   Y        -0.252  -0.279  -0.223  -0.175  -0.251  -0.166  -0.468  -0.536  -0.449
232   Y        -0.252  -0.003  -0.134  -0.183   0.197  -0.013  -0.468  -0.089  -0.301
233   P        -0.252  -0.279  -0.223  -0.435  -0.447  -0.350  -0.468  -0.536  -0.449
234   P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
235   V        -0.755  -1.001  -1.028  -0.770  -1.146  -1.192  -0.675  -0.979  -0.997
236   K        -1.761  -1.717  -1.630  -1.644  -1.497  -1.371  -1.501  -1.416  -1.302
237   P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
238   N        -0.755  -1.001  -1.028  -0.567  -0.919  -0.960  -0.675  -0.979  -0.997
239   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
240   W        -0.755  -1.001  -1.028  -0.308  -0.636  -0.647  -0.675  -0.979  -0.997
241   Q        -0.252  -0.279  -0.223  -0.321  -0.325  -0.231  -0.468  -0.536  -0.449
242   F        -1.068  -1.008  -0.999  -0.794  -0.715  -0.700  -1.088  -0.988  -0.962
243   F         1.134   1.159   1.182   1.285   1.325   1.350   1.184   1.225   1.254
244   D         1.134   1.159   1.182   1.277   1.302   1.343   1.184   1.225   1.254
245   I        -0.252  -0.007  -0.135  -0.439  -0.023  -0.249  -0.468  -0.095  -0.302
246   S        -0.252  -0.003  -0.134  -0.430  -0.052  -0.232  -0.468  -0.089  -0.301
247   N         0.153  -0.024  -0.137   0.324   0.097  -0.090   0.151  -0.121  -0.306
248   L        -1.068  -0.988  -1.002  -1.199  -1.066  -1.110  -1.088  -0.963  -0.965
249   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   S        -1.761  -1.717  -1.630  -1.624  -1.586  -1.444  -1.501  -1.416  -1.302
253   E        -0.252  -0.003  -0.134  -0.128   0.218   0.038  -0.468  -0.089  -0.301
254   I         0.153   0.004  -0.143   0.056  -0.143  -0.375   0.151  -0.077  -0.316
255   P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
256   E        -1.258  -0.995  -1.023  -1.258  -0.842  -0.890  -1.294  -0.972  -0.990
257   V         1.134   1.159   1.182   1.073   1.129   1.159   1.184   1.225   1.254
258   I        -1.258  -0.995  -1.023  -1.249  -0.906  -0.917  -1.294  -0.972  -0.990
259   I         1.134   1.159   1.182   1.095   1.148   1.179   1.184   1.225   1.254
260   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
261   Y         1.134   1.159   1.182   1.269   1.304   1.336   1.184   1.225   1.254
262   S        -0.755  -1.001  -1.028  -0.790  -1.219  -1.267  -0.675  -0.979  -0.997
263   Y         1.134   1.159   1.182   1.269   1.304   1.336   1.184   1.225   1.254
264   Q         1.134   1.159   1.182   1.369   1.392   1.425   1.184   1.225   1.254
265   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
266   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
267   N         1.134   1.159   1.182   1.179   1.235   1.254   1.184   1.225   1.254
268   P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
269   E        -1.761  -1.717  -1.630  -1.583  -1.556  -1.408  -1.501  -1.416  -1.302
270   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
271   I        -0.252  -0.279  -0.223  -0.523  -0.565  -0.470  -0.468  -0.536  -0.449
272   V        -1.761  -1.717  -1.630  -1.498  -1.476  -1.338  -1.501  -1.416  -1.302
273   K        -1.068  -0.991  -1.004  -1.267  -1.087  -1.091  -1.088  -0.966  -0.967
274   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
275   V         1.134   1.159   1.182   1.073   1.129   1.159   1.184   1.225   1.254
276   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   D        -1.068  -1.006  -1.000  -0.795  -0.730  -0.699  -1.088  -0.985  -0.963
278   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
279   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
280   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
281   K         1.134   1.159   1.182   1.285   1.315   1.350   1.184   1.225   1.254
282   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
283   I         0.153   0.004  -0.143   0.056  -0.143  -0.375   0.151  -0.077  -0.316
284   V         1.134   1.159   1.182   1.073   1.129   1.159   1.184   1.225   1.254
285   L         0.153  -0.024  -0.137   0.095  -0.124  -0.276   0.151  -0.121  -0.306
286   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
287   G        -0.252  -0.003  -0.134  -0.550  -0.130  -0.349  -0.468  -0.089  -0.301
288   S        -0.755  -1.001  -1.028  -0.383  -0.795  -0.886  -0.675  -0.979  -0.997
289   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
290   A         1.134   1.159   1.182   0.993   1.050   1.087   1.184   1.225   1.254
291   G        -1.258  -0.995  -1.023  -1.577  -1.152  -1.191  -1.294  -0.972  -0.990
292   S         0.153  -0.024  -0.137   0.183  -0.029  -0.162   0.151  -0.121  -0.306
293   W         1.134   1.159   1.182   1.472   1.490   1.518   1.184   1.225   1.254
294   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
295   A         0.153   0.004  -0.143   0.365   0.122  -0.151   0.151  -0.077  -0.316
296   T        -1.761  -1.717  -1.630  -1.499  -1.461  -1.321  -1.501  -1.416  -1.302
297   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
298   S         0.153   0.004  -0.143   0.269   0.056  -0.227   0.151  -0.077  -0.316
299   I        -0.755  -1.001  -1.028  -0.455  -0.877  -0.941  -0.675  -0.979  -0.997
300   V         1.134   1.159   1.182   1.073   1.129   1.159   1.184   1.225   1.254
301   N        -0.755  -1.001  -1.028  -0.668  -1.057  -1.120  -0.675  -0.979  -0.997
302   E        -1.761  -1.717  -1.630  -1.613  -1.517  -1.366  -1.501  -1.416  -1.302
303   Q        -1.761  -1.717  -1.630  -1.764  -1.608  -1.452  -1.501  -1.416  -1.302
304   L         0.153  -0.024  -0.137   0.051  -0.193  -0.375   0.151  -0.121  -0.306
305   Y        -0.755  -1.001  -1.028  -0.526  -0.830  -0.836  -0.675  -0.979  -0.997
306   E        -1.258  -0.995  -1.023  -1.251  -0.841  -0.885  -1.294  -0.972  -0.990
307   E        -1.068  -1.008  -0.999  -0.923  -0.818  -0.801  -1.088  -0.988  -0.962
308   Y        -1.258  -0.995  -1.023  -1.012  -0.677  -0.698  -1.294  -0.972  -0.990
309   G        -1.258  -0.995  -1.023  -1.536  -1.124  -1.160  -1.294  -0.972  -0.990
310   I         0.153  -0.024  -0.137   0.199  -0.049  -0.253   0.151  -0.121  -0.306
311   P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
312   I        -0.755  -1.001  -1.028  -0.677  -1.054  -1.109  -0.675  -0.979  -0.997
313   V         1.134   1.159   1.182   1.073   1.129   1.159   1.184   1.225   1.254
314   H         0.153   0.004  -0.143   0.442   0.248   0.036   0.151  -0.077  -0.316
315   S         1.134   1.159   1.182   1.005   1.053   1.098   1.184   1.225   1.254
316   R         0.153   0.004  -0.143   0.586   0.368   0.131   0.151  -0.077  -0.316
317   R         1.134   1.159   1.182   1.361   1.390   1.418   1.184   1.225   1.254
318   T         1.134   1.159   1.182   1.129   1.176   1.209   1.184   1.225   1.254
319   A        -1.068  -1.008  -0.999  -1.125  -1.043  -1.019  -1.088  -0.988  -0.962
320   D        -0.375  -0.279  -0.224  -0.391  -0.267  -0.160  -0.675  -0.536  -0.450
321   G         1.134   1.159   1.182   1.016   1.058   1.108   1.184   1.225   1.254
322   T        -1.761  -1.717  -1.630  -1.579  -1.584  -1.447  -1.501  -1.416  -1.302
323   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
324   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
325   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
326   D        -0.755  -1.001  -1.028  -0.732  -1.111  -1.129  -0.675  -0.979  -0.997
327   D        -1.068  -1.006  -1.000  -1.056  -0.926  -0.934  -1.088  -0.985  -0.963
328   A        -1.761  -1.717  -1.630  -1.675  -1.660  -1.535  -1.501  -1.416  -1.302
329   P        -1.761  -1.717  -1.630  -1.666  -1.563  -1.436  -1.501  -1.416  -1.302
330   E        -1.761  -1.717  -1.630  -1.267  -1.217  -1.087  -1.501  -1.416  -1.302
331   Y        -1.761  -1.717  -1.630  -1.727  -1.575  -1.451  -1.501  -1.416  -1.302
332   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
333   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
334   A        -0.252  -0.279  -0.223  -0.550  -0.634  -0.526  -0.468  -0.536  -0.449
335   I         0.153  -0.024  -0.137   0.199  -0.049  -0.253   0.151  -0.121  -0.306
336   G        -0.755  -1.001  -1.028  -0.546  -0.998  -1.092  -0.675  -0.979  -0.997
337   S         0.153   0.373  -0.099   0.092   0.391  -0.294   0.151   0.449  -0.244
338   G        -0.252  -0.279  -0.223  -0.303  -0.443  -0.343  -0.468  -0.536  -0.449
339   Y        -0.755  -1.001  -1.028  -0.436  -0.832  -0.899  -0.675  -0.979  -0.997
340   L        -0.252  -0.007  -0.135  -0.434  -0.077  -0.233  -0.468  -0.095  -0.302
341   N         1.134   1.159   1.182   1.179   1.235   1.254   1.184   1.225   1.254
342   P         1.134   1.159   1.182   1.258   1.301   1.326   1.184   1.225   1.254
343   Q         1.134   1.159   1.182   1.369   1.392   1.425   1.184   1.225   1.254
344   K         1.134   1.159   1.182   1.285   1.315   1.350   1.184   1.225   1.254
345   S         0.153   0.004  -0.143   0.083  -0.125  -0.380   0.151  -0.077  -0.316
346   R         1.134   1.159   1.182   1.361   1.390   1.418   1.184   1.225   1.254
347   I        -0.252  -0.279  -0.223  -0.268  -0.378  -0.291  -0.468  -0.536  -0.449
348   L        -0.252  -0.279  -0.223  -0.251  -0.412  -0.329  -0.468  -0.536  -0.449
349   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
350   Q        -0.252  -0.279  -0.223  -0.066  -0.137  -0.056  -0.468  -0.536  -0.449
351   L         1.134   1.159   1.182   0.947   1.001   1.046   1.184   1.225   1.254
352   C        -1.258  -0.995  -1.023  -1.355  -0.811  -0.931  -1.294  -0.972  -0.990
353   L         0.153   0.004  -0.143   0.174  -0.045  -0.322   0.151  -0.077  -0.316
354   Y        -1.068  -0.988  -1.002  -1.115  -0.925  -0.966  -1.088  -0.963  -0.965
355   S        -0.375  -0.279  -0.224  -0.807  -0.637  -0.534  -0.675  -0.535  -0.450
356   G         0.153  -0.024  -0.137   0.162  -0.077  -0.224   0.151  -0.121  -0.306
357   Y         1.134   1.159   1.182   1.269   1.304   1.336   1.184   1.225   1.254
358   G         0.153   0.004  -0.143   0.097  -0.121  -0.365   0.151  -0.077  -0.316
359   M         0.153   0.004  -0.143   0.257   0.082  -0.133   0.151  -0.077  -0.316
360   D        -1.761  -1.717  -1.630  -1.393  -1.395  -1.259  -1.501  -1.416  -1.302
361   Q        -1.761  -1.717  -1.630  -1.472  -1.385  -1.247  -1.501  -1.416  -1.302
362   I         1.134   1.159   1.182   1.095   1.148   1.179   1.184   1.225   1.254
363   R        -1.258  -0.995  -1.023  -1.179  -0.754  -0.815  -1.294  -0.972  -0.990
364   S        -1.571  -1.582  -1.614  -1.303  -1.410  -1.455  -1.294  -1.307  -1.288
365   V        -1.761  -1.717  -1.630  -1.964  -1.890  -1.746  -1.501  -1.416  -1.302
366   F         1.134   1.159   1.182   1.285   1.325   1.350   1.184   1.225   1.254
367   S         1.134   1.159   1.182   1.005   1.053   1.098   1.184   1.225   1.254
368   G        -1.761  -1.717  -1.630  -1.986  -1.934  -1.779  -1.501  -1.416  -1.302
369   V        -1.258  -0.995  -1.023  -1.258  -0.916  -0.927  -1.294  -0.972  -0.990
370   Y         1.134   1.159   1.182   1.251   1.281   1.319   1.184   1.225   1.254
371   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
372   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P0CX77
Output conservation file - output/P0CX77
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
