1     M         1.012   1.029   1.106   1.214   1.234   1.339   1.081   1.104   1.214
2     P        -1.350  -1.274  -1.240  -1.391  -1.283  -1.220  -1.369  -1.273  -1.161
3     T        -1.350  -1.299  -1.229  -1.506  -1.423  -1.323  -1.369  -1.302  -1.151
4     L        -2.302  -2.245  -1.967  -2.234  -2.112  -1.751  -1.861  -1.803  -1.459
5     V        -1.448  -1.361  -1.246  -1.491  -1.383  -1.169  -1.469  -1.374  -1.168
6     N        -1.286  -1.307  -1.241  -1.140  -1.204  -1.100  -1.273  -1.300  -1.161
7     G        -1.448  -1.457  -1.262  -1.549  -1.556  -1.280  -1.469  -1.469  -1.182
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    R        -1.350  -1.435  -1.253  -1.305  -1.439  -1.185  -1.369  -1.439  -1.174
13    D        -1.855  -1.881  -1.646  -1.919  -1.948  -1.591  -1.657  -1.663  -1.345
14    S        -1.350  -1.312  -1.245  -1.468  -1.432  -1.289  -1.369  -1.334  -1.166
15    T        -2.514  -2.497  -2.227  -2.279  -2.311  -1.928  -1.898  -1.871  -1.533
16    E        -1.431  -1.388  -1.244  -1.402  -1.348  -1.105  -1.457  -1.399  -1.166
17    G        -2.193  -2.159  -1.953  -2.158  -2.115  -1.839  -1.788  -1.748  -1.449
18    F        -0.911  -0.854  -0.761  -1.070  -0.979  -0.857  -1.126  -1.043  -0.903
19    D        -0.653  -0.688  -0.728  -0.623  -0.685  -0.712  -0.795  -0.850  -0.863
20    T         1.012   1.029   1.106   1.054   1.072   1.195   1.081   1.104   1.214
21    D         0.315   0.165   0.023   0.429   0.241   0.038   0.309   0.077  -0.197
22    I         1.012   1.029   1.106   0.952   0.979   1.104   1.081   1.104   1.214
23    I        -0.028  -0.124  -0.067  -0.169  -0.339  -0.268  -0.243  -0.419  -0.361
24    T         1.012   1.029   1.106   1.054   1.072   1.195   1.081   1.104   1.214
25    L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
26    P        -0.911  -0.854  -0.761  -1.016  -0.931  -0.807  -1.126  -1.043  -0.903
27    R         0.315   0.283   0.034   0.528   0.488   0.064   0.309   0.260  -0.176
28    F         1.012   1.029   1.106   1.119   1.141   1.254   1.081   1.104   1.214
29    I         0.315   0.165   0.023   0.304   0.094  -0.183   0.309   0.077  -0.197
30    I        -0.974  -1.016  -1.200  -1.014  -1.075  -1.341  -0.905  -0.960  -1.118
31    E        -0.790  -0.739  -0.737  -0.790  -0.734  -0.713  -1.015  -0.961  -0.875
32    H        -0.974  -0.826  -1.190  -0.699  -0.513  -0.978  -0.905  -0.724  -1.107
33    Q         1.012   1.029   1.106   1.195   1.223   1.322   1.081   1.104   1.214
34    K        -2.193  -2.208  -1.959  -1.892  -1.926  -1.552  -1.788  -1.781  -1.454
35    -        -1.452  -1.461  -1.261  -1.571  -1.592  -1.292  -1.461  -1.462  -1.181
36    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
47    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    Q        -2.514  -2.464  -2.223  -2.349  -2.299  -1.941  -1.898  -1.850  -1.531
50    F        -2.072  -2.109  -1.945  -1.928  -1.976  -1.758  -1.677  -1.700  -1.444
51    K        -1.232  -1.208  -1.218  -1.136  -1.095  -1.094  -1.236  -1.190  -1.138
52    N        -1.431  -1.426  -1.252  -1.485  -1.495  -1.226  -1.457  -1.444  -1.174
53    A         0.315   0.334   0.039   0.360   0.383  -0.067   0.309   0.336  -0.167
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    T        -0.349  -0.343  -0.670  -0.166  -0.166  -0.655  -0.353  -0.344  -0.781
58    G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
59    D        -0.270  -0.247  -0.081  -0.546  -0.514  -0.236  -0.684  -0.648  -0.387
60    F        -0.212  -0.180  -0.066  -0.453  -0.391  -0.251  -0.574  -0.521  -0.359
61    T        -0.212  -0.222  -0.081  -0.479  -0.510  -0.270  -0.574  -0.601  -0.386
62    L         0.315   0.394   0.042   0.233   0.336  -0.099   0.309   0.422  -0.162
63    V        -0.028   0.043  -0.026  -0.294  -0.175  -0.294  -0.243  -0.125  -0.285
64    L         0.315   0.165   0.023   0.244   0.070  -0.098   0.309   0.077  -0.197
65    N         0.315   0.165   0.023   0.507   0.320   0.102   0.309   0.077  -0.197
66    A        -0.270  -0.248  -0.082  -0.630  -0.596  -0.312  -0.684  -0.649  -0.388
67    L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
68    Q         0.315   0.369   0.041   0.552   0.629   0.073   0.309   0.387  -0.163
69    F         1.012   1.029   1.106   1.119   1.141   1.254   1.081   1.104   1.214
70    A        -0.028  -0.124  -0.067  -0.154  -0.339  -0.278  -0.243  -0.419  -0.361
71    F         1.012   1.029   1.106   1.119   1.141   1.254   1.081   1.104   1.214
72    K         1.012   1.029   1.106   1.011   1.027   1.157   1.081   1.104   1.214
73    F         0.315   0.165   0.023   0.490   0.280   0.009   0.309   0.077  -0.197
74    V         0.315   0.387   0.042   0.332   0.429  -0.068   0.309   0.413  -0.162
75    S        -0.212  -0.148  -0.063  -0.502  -0.385  -0.269  -0.574  -0.461  -0.352
76    H        -1.232  -1.323  -1.232  -0.919  -1.040  -0.942  -1.236  -1.316  -1.153
77    T        -0.790  -0.869  -0.742  -0.843  -0.933  -0.723  -1.015  -1.084  -0.880
78    I         1.012   1.029   1.106   0.952   0.979   1.104   1.081   1.104   1.214
79    R         1.012   1.029   1.106   1.158   1.181   1.288   1.081   1.104   1.214
80    R         0.315   0.283   0.034   0.536   0.496   0.085   0.309   0.260  -0.176
81    A         0.315   0.334   0.039   0.360   0.383  -0.067   0.309   0.336  -0.167
82    E        -0.028  -0.103  -0.061  -0.072  -0.213  -0.172  -0.243  -0.380  -0.349
83    L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
84    V         1.012   1.029   1.106   1.021   1.042   1.165   1.081   1.104   1.214
85    N         1.012   1.029   1.106   1.096   1.121   1.233   1.081   1.104   1.214
86    L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
87    V        -0.349  -0.434  -0.681  -0.274  -0.395  -0.767  -0.353  -0.476  -0.795
88    G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
89    L        -0.349  -0.234  -0.656  -0.421  -0.261  -0.868  -0.353  -0.201  -0.761
90    A        -0.270  -0.250  -0.081  -0.630  -0.601  -0.310  -0.684  -0.653  -0.387
91    G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
92    A        -1.310  -1.310  -1.236  -1.468  -1.465  -1.320  -1.346  -1.329  -1.158
93    S        -0.790  -0.789  -0.732  -1.019  -1.004  -0.885  -1.015  -0.994  -0.867
94    N         1.012   1.029   1.106   1.096   1.121   1.233   1.081   1.104   1.214
95    F        -0.349  -0.434  -0.681  -0.255  -0.383  -0.726  -0.353  -0.476  -0.795
96    T         1.012   1.029   1.106   1.054   1.072   1.195   1.081   1.104   1.214
97    G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
98    D         1.012   1.029   1.106   1.017   1.040   1.162   1.081   1.104   1.214
99    Q        -1.431  -1.352  -1.236  -1.449  -1.326  -1.153  -1.457  -1.355  -1.157
100   Q         1.012   1.029   1.106   1.195   1.223   1.322   1.081   1.104   1.214
101   K         1.012   1.029   1.106   1.011   1.027   1.157   1.081   1.104   1.214
102   K         1.012   1.029   1.106   1.011   1.027   1.157   1.081   1.104   1.214
103   L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
104   D         1.012   1.029   1.106   1.017   1.040   1.162   1.081   1.104   1.214
105   V         0.315   0.283   0.034   0.400   0.357  -0.029   0.309   0.260  -0.176
106   L        -0.212  -0.148  -0.063  -0.605  -0.470  -0.370  -0.574  -0.461  -0.352
107   G        -0.349  -0.526  -0.693  -0.344  -0.588  -0.793  -0.353  -0.593  -0.812
108   D        -0.028  -0.124  -0.067  -0.081  -0.249  -0.178  -0.243  -0.419  -0.361
109   E        -0.028  -0.124  -0.067  -0.084  -0.266  -0.205  -0.243  -0.419  -0.361
110   I         0.315   0.165   0.023   0.304   0.094  -0.183   0.309   0.077  -0.197
111   F         1.012   1.029   1.106   1.119   1.141   1.254   1.081   1.104   1.214
112   I         1.012   1.029   1.106   0.952   0.979   1.104   1.081   1.104   1.214
113   N        -0.349  -0.526  -0.693  -0.127  -0.377  -0.670  -0.353  -0.593  -0.812
114   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
115   M         1.012   1.029   1.106   1.214   1.234   1.339   1.081   1.104   1.214
116   R        -0.212  -0.221  -0.080  -0.374  -0.399  -0.165  -0.574  -0.597  -0.384
117   A        -0.790  -0.722  -0.731  -1.054  -0.947  -0.950  -1.015  -0.921  -0.868
118   S        -0.349  -0.343  -0.670  -0.219  -0.214  -0.629  -0.353  -0.344  -0.781
119   G        -0.028   0.049  -0.015  -0.241  -0.120  -0.217  -0.243  -0.115  -0.265
120   I        -1.752  -1.730  -1.625  -1.593  -1.579  -1.395  -1.567  -1.544  -1.330
121   I        -0.911  -0.924  -0.766  -0.997  -0.998  -0.763  -1.126  -1.144  -0.909
122   K         0.315   0.165   0.023   0.387   0.175  -0.067   0.309   0.077  -0.197
123   V        -0.270  -0.238  -0.078  -0.702  -0.657  -0.378  -0.684  -0.630  -0.380
124   L        -0.349  -0.375  -0.668  -0.421  -0.447  -0.889  -0.353  -0.386  -0.778
125   V         1.012   1.029   1.106   1.021   1.042   1.165   1.081   1.104   1.214
126   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
127   E         1.012   1.029   1.106   1.040   1.059   1.183   1.081   1.104   1.214
128   E         1.012   1.029   1.106   1.040   1.059   1.183   1.081   1.104   1.214
129   Q        -0.028  -0.124  -0.067   0.073  -0.106  -0.079  -0.243  -0.419  -0.361
130   E         1.012   1.029   1.106   1.040   1.059   1.183   1.081   1.104   1.214
131   D         0.315   0.165   0.023   0.429   0.241   0.038   0.309   0.077  -0.197
132   L         0.315   0.165   0.023   0.203   0.010  -0.211   0.309   0.077  -0.197
133   I         1.012   1.029   1.106   0.952   0.979   1.104   1.081   1.104   1.214
134   V         0.315   0.165   0.023   0.420   0.224   0.008   0.309   0.077  -0.197
135   F         0.315   0.283   0.034   0.499   0.458   0.057   0.309   0.260  -0.176
136   P        -1.752  -1.788  -1.626  -1.560  -1.628  -1.397  -1.567  -1.585  -1.330
137   T        -1.752  -1.788  -1.636  -1.854  -1.912  -1.637  -1.567  -1.585  -1.337
138   N        -2.193  -2.180  -1.952  -2.231  -2.206  -1.859  -1.788  -1.762  -1.449
139   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
140   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
141   G         0.315   0.165   0.023   0.227   0.025  -0.200   0.309   0.077  -0.197
142   S        -1.431  -1.362  -1.249  -1.467  -1.365  -1.207  -1.457  -1.379  -1.171
143   Y         1.012   1.029   1.106   1.154   1.172   1.285   1.081   1.104   1.214
144   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
145   V         0.315   0.369   0.041   0.391   0.460  -0.038   0.309   0.387  -0.163
146   C        -0.974  -1.125  -1.211  -0.552  -0.795  -1.016  -0.905  -1.083  -1.129
147   C        -0.028   0.049  -0.015   0.163   0.284   0.109  -0.243  -0.115  -0.265
148   D         1.012   1.029   1.106   1.017   1.040   1.162   1.081   1.104   1.214
149   P         1.012   1.029   1.106   1.177   1.200   1.305   1.081   1.104   1.214
150   I         1.012   1.029   1.106   0.952   0.979   1.104   1.081   1.104   1.214
151   D         1.012   1.029   1.106   1.017   1.040   1.162   1.081   1.104   1.214
152   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
153   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
154   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
155   N         1.012   1.029   1.106   1.096   1.121   1.233   1.081   1.104   1.214
156   L        -0.212  -0.180  -0.066  -0.652  -0.589  -0.403  -0.574  -0.521  -0.359
157   D         1.012   1.029   1.106   1.017   1.040   1.162   1.081   1.104   1.214
158   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
159   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
160   V         1.012   1.029   1.106   1.021   1.042   1.165   1.081   1.104   1.214
161   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
162   V         1.012   1.029   1.106   1.021   1.042   1.165   1.081   1.104   1.214
163   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
164   T         1.012   1.029   1.106   1.054   1.072   1.195   1.081   1.104   1.214
165   I         1.012   1.029   1.106   0.952   0.979   1.104   1.081   1.104   1.214
166   A        -0.653  -0.539  -0.714  -0.594  -0.420  -0.727  -0.795  -0.636  -0.842
167   S        -0.790  -0.860  -0.743  -1.134  -1.215  -1.005  -1.015  -1.071  -0.881
168   I        -0.653  -0.578  -0.703  -0.784  -0.669  -0.894  -0.795  -0.697  -0.828
169   F        -0.790  -0.860  -0.743  -0.733  -0.801  -0.616  -1.015  -1.071  -0.881
170   R        -0.028   0.077  -0.038  -0.067   0.087  -0.100  -0.243  -0.067  -0.307
171   L         0.315   0.394   0.042   0.193   0.303  -0.205   0.309   0.422  -0.162
172   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
173   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
174   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
175   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
176   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
177   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
178   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
179   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   L        -2.514  -2.491  -2.226  -2.356  -2.315  -1.894  -1.898  -1.868  -1.532
182   P        -0.212  -0.183  -0.073  -0.338  -0.296  -0.125  -0.574  -0.526  -0.372
183   D        -0.270  -0.250  -0.082  -0.684  -0.653  -0.360  -0.684  -0.654  -0.389
184   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
185   S        -1.431  -1.351  -1.241  -1.466  -1.350  -1.175  -1.457  -1.365  -1.163
186   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
187   T        -1.310  -1.307  -1.225  -1.453  -1.439  -1.313  -1.346  -1.327  -1.148
188   I         0.315   0.165   0.023   0.331   0.131  -0.107   0.309   0.077  -0.197
189   N        -1.431  -1.477  -1.250  -1.551  -1.620  -1.264  -1.457  -1.481  -1.171
190   D         1.012   1.029   1.106   1.017   1.040   1.162   1.081   1.104   1.214
191   V         0.315   0.165   0.023   0.391   0.183  -0.074   0.309   0.077  -0.197
192   L         0.315   0.394   0.042   0.198   0.307  -0.190   0.309   0.422  -0.162
193   R         0.315   0.165   0.023   0.536   0.331   0.063   0.309   0.077  -0.197
194   C        -1.232  -1.067  -1.212  -0.991  -0.756  -1.007  -1.236  -1.039  -1.132
195   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
196   K        -1.232  -1.175  -1.219  -1.145  -1.097  -1.079  -1.236  -1.181  -1.141
197   E         0.315   0.369   0.041   0.420   0.485   0.003   0.309   0.387  -0.163
198   M         0.315   0.165   0.023   0.567   0.348   0.038   0.309   0.077  -0.197
199   V         1.012   1.029   1.106   1.021   1.042   1.165   1.081   1.104   1.214
200   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
201   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
202   C        -0.212  -0.148  -0.063  -0.441  -0.348  -0.183  -0.574  -0.461  -0.352
203   Y         0.315   0.165   0.023   0.548   0.346   0.102   0.309   0.077  -0.197
204   A        -0.028   0.043  -0.026  -0.080   0.029  -0.125  -0.243  -0.125  -0.285
205   M         1.012   1.029   1.106   1.214   1.234   1.339   1.081   1.104   1.214
206   Y         1.012   1.029   1.106   1.154   1.172   1.285   1.081   1.104   1.214
207   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
208   S         0.315   0.387   0.042   0.360   0.451  -0.062   0.309   0.413  -0.162
209   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
210   T        -0.212  -0.148  -0.063  -0.448  -0.340  -0.214  -0.574  -0.461  -0.352
211   H        -0.349  -0.481  -0.688   0.043  -0.137  -0.482  -0.353  -0.536  -0.805
212   L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
213   V        -1.232  -1.190  -1.215  -1.193  -1.132  -1.195  -1.236  -1.168  -1.136
214   L         0.315   0.165   0.023   0.193  -0.004  -0.240   0.309   0.077  -0.197
215   T         0.315   0.334   0.039   0.425   0.446  -0.013   0.309   0.336  -0.167
216   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
217   L        -0.974  -1.016  -1.200  -0.778  -0.858  -1.161  -0.905  -0.960  -1.118
218   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
219   D        -2.193  -2.139  -1.948  -1.954  -1.913  -1.640  -1.788  -1.736  -1.447
220   G        -0.349  -0.526  -0.693  -0.367  -0.615  -0.848  -0.353  -0.593  -0.812
221   V         0.315   0.334   0.039   0.440   0.463   0.087   0.309   0.336  -0.167
222   D        -0.028   0.043  -0.026  -0.030   0.085  -0.079  -0.243  -0.125  -0.285
223   G         0.315   0.343   0.049   0.203   0.245  -0.218   0.309   0.349  -0.150
224   F         1.012   1.029   1.106   1.119   1.141   1.254   1.081   1.104   1.214
225   T         1.012   1.029   1.106   1.054   1.072   1.195   1.081   1.104   1.214
226   L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
227   D         1.012   1.029   1.106   1.017   1.040   1.162   1.081   1.104   1.214
228   T        -0.974  -1.039  -1.202  -0.729  -0.823  -1.067  -0.905  -0.986  -1.120
229   N        -1.752  -1.818  -1.636  -1.577  -1.697  -1.437  -1.567  -1.608  -1.338
230   L        -0.349  -0.526  -0.693  -0.421  -0.663  -0.930  -0.353  -0.593  -0.812
231   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
232   E         1.012   1.029   1.106   1.040   1.059   1.183   1.081   1.104   1.214
233   F         1.012   1.029   1.106   1.119   1.141   1.254   1.081   1.104   1.214
234   I         1.012   1.029   1.106   0.952   0.979   1.104   1.081   1.104   1.214
235   L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
236   T         1.012   1.029   1.106   1.054   1.072   1.195   1.081   1.104   1.214
237   H        -0.653  -0.517  -0.705  -0.391  -0.195  -0.492  -0.795  -0.604  -0.832
238   P         0.315   0.283   0.034   0.576   0.539   0.156   0.309   0.260  -0.176
239   N        -0.974  -0.823  -1.174  -0.690  -0.494  -1.000  -0.905  -0.722  -1.091
240   L        -0.028  -0.124  -0.067  -0.228  -0.369  -0.249  -0.243  -0.419  -0.361
241   R        -0.990  -0.982  -0.776  -1.130  -1.133  -0.810  -1.236  -1.219  -0.922
242   I        -0.790  -0.794  -0.727  -1.082  -1.058  -0.901  -1.015  -1.003  -0.863
243   P         1.012   1.029   1.106   1.177   1.200   1.305   1.081   1.104   1.214
244   P        -2.514  -2.464  -2.223  -2.274  -2.206  -1.863  -1.898  -1.850  -1.531
245   Q        -1.431  -1.467  -1.252  -1.501  -1.542  -1.256  -1.457  -1.470  -1.173
246   K        -0.790  -0.784  -0.727  -0.793  -0.760  -0.650  -1.015  -0.986  -0.863
247   A        -1.232  -1.118  -1.209  -1.253  -1.074  -1.177  -1.236  -1.088  -1.130
248   I         1.012   1.029   1.106   0.952   0.979   1.104   1.081   1.104   1.214
249   Y         1.012   1.029   1.106   1.154   1.172   1.285   1.081   1.104   1.214
250   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
251   I        -0.790  -0.753  -0.727  -1.027  -0.961  -0.928  -1.015  -0.960  -0.863
252   N         1.012   1.029   1.106   1.096   1.121   1.233   1.081   1.104   1.214
253   E         1.012   1.029   1.106   1.040   1.059   1.183   1.081   1.104   1.214
254   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
255   N        -0.028  -0.032  -0.041   0.014   0.003  -0.043  -0.243  -0.255  -0.313
256   T        -0.790  -0.734  -0.737  -0.949  -0.874  -0.803  -1.015  -0.940  -0.876
257   L        -2.072  -1.980  -1.932  -1.959  -1.852  -1.695  -1.677  -1.586  -1.434
258   Y        -0.974  -0.986  -1.184  -0.699  -0.720  -1.095  -0.905  -0.914  -1.101
259   W         0.315   0.343   0.049   0.709   0.745   0.282   0.309   0.349  -0.150
260   N        -2.193  -2.105  -1.943  -2.083  -1.964  -1.713  -1.788  -1.708  -1.443
261   E        -0.790  -0.739  -0.734  -0.898  -0.848  -0.759  -1.015  -0.961  -0.872
262   T        -2.514  -2.500  -2.226  -2.381  -2.368  -1.989  -1.898  -1.873  -1.532
263   I        -0.790  -0.722  -0.737  -1.007  -0.928  -0.887  -1.015  -0.950  -0.875
264   R        -1.752  -1.669  -1.620  -1.670  -1.562  -1.439  -1.567  -1.480  -1.325
265   T        -2.072  -2.059  -1.939  -1.853  -1.860  -1.671  -1.677  -1.661  -1.440
266   F        -0.270  -0.248  -0.083  -0.390  -0.359  -0.098  -0.684  -0.649  -0.389
267   I        -0.653  -0.701  -0.725  -0.746  -0.828  -0.878  -0.795  -0.875  -0.858
268   E        -1.752  -1.763  -1.622  -1.737  -1.757  -1.527  -1.567  -1.567  -1.326
269   K        -1.873  -1.853  -1.637  -1.916  -1.884  -1.532  -1.677  -1.642  -1.338
270   V        -0.349  -0.270  -0.652  -0.421  -0.307  -0.862  -0.353  -0.247  -0.756
271   K         1.012   1.029   1.106   1.011   1.027   1.157   1.081   1.104   1.214
272   Q        -1.232  -1.131  -1.208  -1.156  -1.008  -1.087  -1.236  -1.108  -1.128
273   P        -1.717  -1.735  -1.622  -1.534  -1.584  -1.484  -1.513  -1.527  -1.326
274   Q        -1.122  -1.083  -1.201  -0.859  -0.800  -1.063  -1.081  -1.030  -1.119
275   A        -1.122  -1.088  -1.199  -0.984  -0.936  -1.127  -1.081  -1.036  -1.117
276   D        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
277   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
278   N        -1.855  -1.858  -1.640  -1.930  -1.953  -1.636  -1.657  -1.645  -1.341
279   N        -1.122  -1.088  -1.199  -1.189  -1.145  -1.303  -1.081  -1.036  -1.117
280   K         0.315   0.343   0.049   0.394   0.424   0.000   0.309   0.349  -0.150
281   P         0.315   0.343   0.049   0.533   0.572   0.071   0.309   0.349  -0.150
282   F         0.315   0.387   0.042   0.548   0.633   0.137   0.309   0.413  -0.162
283   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
284   A        -0.028   0.016  -0.040  -0.196  -0.122  -0.288  -0.243  -0.170  -0.311
285   R         1.012   1.029   1.106   1.158   1.181   1.288   1.081   1.104   1.214
286   Y         1.012   1.029   1.106   1.154   1.172   1.285   1.081   1.104   1.214
287   V         0.315   0.387   0.042   0.332   0.429  -0.068   0.309   0.413  -0.162
288   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
289   S         0.315   0.369   0.041   0.330   0.398  -0.080   0.309   0.387  -0.163
290   M         1.012   1.029   1.106   1.214   1.234   1.339   1.081   1.104   1.214
291   V         1.012   1.029   1.106   1.021   1.042   1.165   1.081   1.104   1.214
292   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
293   D         1.012   1.029   1.106   1.017   1.040   1.162   1.081   1.104   1.214
294   V        -0.974  -1.053  -1.204  -0.790  -0.918  -1.151  -0.905  -1.005  -1.122
295   H         0.315   0.165   0.023   0.635   0.435   0.183   0.309   0.077  -0.197
296   R         1.012   1.029   1.106   1.158   1.181   1.288   1.081   1.104   1.214
297   T         1.012   1.029   1.106   1.054   1.072   1.195   1.081   1.104   1.214
298   F        -0.990  -0.945  -0.763  -1.369  -1.304  -0.991  -1.236  -1.175  -0.906
299   L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
300   Y         1.012   1.029   1.106   1.154   1.172   1.285   1.081   1.104   1.214
301   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
302   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
303   L        -0.911  -0.909  -0.763  -1.198  -1.170  -0.923  -1.126  -1.124  -0.906
304   F         1.012   1.029   1.106   1.119   1.141   1.254   1.081   1.104   1.214
305   A        -0.028   0.047  -0.029  -0.154  -0.035  -0.200  -0.243  -0.119  -0.290
306   Y         1.012   1.029   1.106   1.154   1.172   1.285   1.081   1.104   1.214
307   P         1.012   1.029   1.106   1.177   1.200   1.305   1.081   1.104   1.214
308   C        -0.984  -0.927  -0.770  -1.191  -1.091  -0.844  -1.225  -1.145  -0.914
309   D         0.254   0.221   0.026   0.296   0.252  -0.078   0.216   0.165  -0.191
310   K        -0.756  -0.683  -0.723  -0.859  -0.756  -0.795  -0.936  -0.837  -0.854
311   K        -0.461  -0.447  -0.683  -0.445  -0.433  -0.880  -0.504  -0.485  -0.798
312   S        -1.350  -1.268  -1.229  -1.493  -1.368  -1.318  -1.369  -1.274  -1.151
313   P        -0.165  -0.143  -0.059  -0.210  -0.176  -0.088  -0.488  -0.452  -0.345
314   N        -1.232  -1.233  -1.223  -1.161  -1.199  -1.171  -1.236  -1.248  -1.146
315   G         0.315   0.343   0.049   0.203   0.245  -0.218   0.309   0.349  -0.150
316   K         1.012   1.029   1.106   1.011   1.027   1.157   1.081   1.104   1.214
317   L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
318   R         1.012   1.029   1.106   1.158   1.181   1.288   1.081   1.104   1.214
319   L        -0.653  -0.669  -0.722  -0.898  -0.929  -0.983  -0.795  -0.824  -0.855
320   L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
321   Y         1.012   1.029   1.106   1.154   1.172   1.285   1.081   1.104   1.214
322   E         1.012   1.029   1.106   1.040   1.059   1.183   1.081   1.104   1.214
323   A        -0.790  -0.741  -0.732  -0.778  -0.676  -0.717  -1.015  -0.936  -0.867
324   F         0.315   0.165   0.023   0.495   0.288   0.023   0.309   0.077  -0.197
325   P         1.012   1.029   1.106   1.177   1.200   1.305   1.081   1.104   1.214
326   M         1.012   1.029   1.106   1.214   1.234   1.339   1.081   1.104   1.214
327   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
328   F        -1.232  -1.235  -1.229  -1.069  -1.082  -1.093  -1.236  -1.241  -1.151
329   L        -0.028  -0.103  -0.061  -0.317  -0.445  -0.393  -0.243  -0.380  -0.349
330   M        -1.310  -1.372  -1.234  -1.241  -1.323  -1.120  -1.346  -1.389  -1.156
331   E         1.012   1.029   1.106   1.040   1.059   1.183   1.081   1.104   1.214
332   Q         0.315   0.165   0.023   0.586   0.392   0.127   0.309   0.077  -0.197
333   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
334   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
335   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
336   K        -2.072  -2.102  -1.951  -1.991  -2.032  -1.866  -1.677  -1.695  -1.448
337   A         1.012   1.029   1.106   0.989   1.010   1.137   1.081   1.104   1.214
338   V        -0.028   0.043  -0.030  -0.124  -0.008  -0.177  -0.243  -0.124  -0.292
339   N        -0.349  -0.473  -0.673  -0.131  -0.311  -0.644  -0.353  -0.526  -0.786
340   D        -0.349  -0.473  -0.673  -0.237  -0.422  -0.770  -0.353  -0.526  -0.786
341   R        -1.232  -1.139  -1.218  -1.121  -0.989  -1.064  -1.236  -1.114  -1.139
342   G         0.315   0.165   0.023   0.261   0.076  -0.105   0.309   0.077  -0.197
343   E        -0.349  -0.526  -0.693  -0.179  -0.428  -0.705  -0.353  -0.593  -0.812
344   R         1.012   1.029   1.106   1.158   1.181   1.288   1.081   1.104   1.214
345   I         0.315   0.165   0.023   0.361   0.176  -0.024   0.309   0.077  -0.197
346   L         1.012   1.029   1.106   0.823   0.854   0.988   1.081   1.104   1.214
347   D        -0.028  -0.063  -0.057  -0.099  -0.165  -0.190  -0.243  -0.309  -0.342
348   L        -0.653  -0.722  -0.714  -0.898  -0.972  -0.967  -0.795  -0.863  -0.841
349   V        -0.028   0.049  -0.015  -0.165  -0.033  -0.205  -0.243  -0.115  -0.265
350   P         1.012   1.029   1.106   1.177   1.200   1.305   1.081   1.104   1.214
351   S        -1.552  -1.563  -1.607  -1.357  -1.399  -1.455  -1.346  -1.358  -1.312
352   H        -1.232  -1.208  -1.218  -1.097  -1.038  -1.120  -1.236  -1.190  -1.138
353   I         0.315   0.283   0.034   0.304   0.267  -0.160   0.309   0.260  -0.176
354   H         1.012   1.029   1.106   1.237   1.257   1.359   1.081   1.104   1.214
355   D        -0.349  -0.375  -0.668  -0.239  -0.277  -0.764  -0.353  -0.386  -0.778
356   K         0.315   0.334   0.039   0.411   0.431   0.029   0.309   0.336  -0.167
357   S         0.315   0.165   0.023   0.330   0.123  -0.114   0.309   0.077  -0.197
358   S        -0.212  -0.216  -0.079  -0.588  -0.612  -0.392  -0.574  -0.588  -0.382
359   I         0.315   0.334   0.039   0.332   0.362  -0.073   0.309   0.336  -0.167
360   W        -0.349  -0.473  -0.673   0.097  -0.080  -0.452  -0.353  -0.526  -0.786
361   L         0.315   0.165   0.023   0.233   0.053  -0.128   0.309   0.077  -0.197
362   G         1.012   1.029   1.106   0.852   0.877   1.014   1.081   1.104   1.214
363   S         1.012   1.029   1.106   0.954   0.975   1.105   1.081   1.104   1.214
364   S        -1.310  -1.319  -1.237  -1.402  -1.407  -1.225  -1.346  -1.345  -1.160
365   G        -0.349  -0.526  -0.693  -0.342  -0.582  -0.788  -0.353  -0.593  -0.812
366   E         0.315   0.394   0.042   0.420   0.516   0.004   0.309   0.422  -0.162
367   I        -0.212  -0.167  -0.070  -0.475  -0.393  -0.263  -0.574  -0.497  -0.366
368   D        -0.270  -0.235  -0.080  -0.546  -0.486  -0.233  -0.684  -0.624  -0.385
369   K        -0.349  -0.290  -0.664  -0.194  -0.132  -0.646  -0.353  -0.278  -0.772
370   F        -1.232  -1.292  -1.229  -1.075  -1.167  -1.110  -1.236  -1.285  -1.149
371   L        -0.653  -0.747  -0.734  -0.888  -1.039  -0.995  -0.795  -0.927  -0.870
372   D        -0.974  -0.872  -1.180  -0.799  -0.668  -1.117  -0.905  -0.782  -1.096
373   H        -0.790  -0.815  -0.739  -0.670  -0.712  -0.588  -1.015  -1.036  -0.878
374   I        -1.232  -1.285  -1.231  -1.334  -1.369  -1.292  -1.236  -1.278  -1.152
375   G        -0.593  -0.606  -0.707  -0.738  -0.754  -0.924  -0.684  -0.701  -0.831
376   K         1.012   1.029   1.106   1.011   1.027   1.157   1.081   1.104   1.214
377   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
378   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P09201
Output conservation file - output/P09201
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
