1     M         0.954   0.970   1.026   1.157   1.176   1.246   1.012   1.034   1.113
2     A        -0.661  -0.615  -0.736  -0.620  -0.569  -0.781  -0.805  -0.753  -0.880
3     S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     K        -0.474  -0.527  -0.718  -0.510  -0.588  -0.896  -0.524  -0.602  -0.852
6     E        -1.845  -1.817  -1.639  -1.940  -1.875  -1.641  -1.649  -1.611  -1.365
7     I        -1.275  -1.357  -1.253  -1.231  -1.380  -1.242  -1.268  -1.356  -1.194
8     R        -2.181  -2.149  -1.944  -1.960  -1.949  -1.631  -1.780  -1.737  -1.471
9     R        -0.661  -0.730  -0.743  -0.618  -0.737  -0.866  -0.805  -0.881  -0.889
10    E        -1.298  -1.267  -1.233  -1.399  -1.352  -1.272  -1.340  -1.289  -1.176
11    R        -1.298  -1.281  -1.234  -1.315  -1.319  -1.215  -1.340  -1.301  -1.177
12    F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
13    L        -1.298  -1.157  -1.232  -1.597  -1.365  -1.421  -1.340  -1.180  -1.175
14    N        -1.415  -1.254  -1.248  -1.450  -1.184  -1.217  -1.447  -1.254  -1.190
15    V        -0.661  -0.679  -0.734  -0.671  -0.675  -0.813  -0.805  -0.804  -0.876
16    F         0.278   0.165  -0.014   0.395   0.232  -0.117   0.264   0.089  -0.237
17    P        -0.366  -0.199  -0.676  -0.060   0.152  -0.603  -0.378  -0.157  -0.795
18    K        -2.154  -2.108  -1.931  -2.033  -1.976  -1.709  -1.767  -1.710  -1.463
19    L        -0.366  -0.512  -0.704  -0.476  -0.668  -0.923  -0.378  -0.573  -0.833
20    V        -0.366  -0.496  -0.704  -0.197  -0.381  -0.727  -0.378  -0.551  -0.833
21    E        -0.661  -0.677  -0.733  -0.726  -0.740  -0.841  -0.805  -0.801  -0.874
22    E         0.278   0.182  -0.011   0.278   0.157  -0.137   0.264   0.117  -0.232
23    L         0.278   0.165  -0.014   0.092  -0.051  -0.304   0.264   0.089  -0.237
24    N        -1.843  -1.790  -1.631  -1.858  -1.804  -1.560  -1.660  -1.591  -1.360
25    A        -2.154  -2.134  -1.931  -1.987  -1.959  -1.694  -1.767  -1.729  -1.463
26    S        -1.726  -1.662  -1.620  -1.699  -1.636  -1.571  -1.554  -1.491  -1.352
27    L         0.278   0.182  -0.011   0.096  -0.021  -0.289   0.264   0.117  -0.232
28    L        -2.465  -2.283  -2.189  -2.464  -2.168  -2.070  -1.874  -1.719  -1.540
29    A        -1.726  -1.739  -1.617  -1.576  -1.613  -1.434  -1.554  -1.552  -1.349
30    Y        -0.366  -0.512  -0.704  -0.190  -0.397  -0.742  -0.378  -0.573  -0.833
31    G        -0.911  -0.922  -0.791  -0.993  -1.026  -0.852  -1.126  -1.135  -0.949
32    M        -0.661  -0.807  -0.761  -0.567  -0.851  -0.845  -0.805  -0.995  -0.912
33    P         0.954   0.970   1.026   1.138   1.156   1.229   1.012   1.034   1.113
34    K        -1.415  -1.428  -1.255  -1.552  -1.569  -1.339  -1.447  -1.435  -1.197
35    E        -0.794  -0.851  -0.757  -1.021  -1.088  -0.908  -1.019  -1.069  -0.909
36    A        -0.366  -0.565  -0.713  -0.170  -0.430  -0.653  -0.378  -0.644  -0.846
37    C        -1.532  -1.650  -1.614  -1.318  -1.529  -1.461  -1.340  -1.451  -1.345
38    D        -1.222  -1.262  -1.227  -1.270  -1.302  -1.248  -1.233  -1.251  -1.169
39    W         0.954   0.970   1.026   1.205   1.227   1.289   1.012   1.034   1.113
40    Y        -0.233  -0.183  -0.108  -0.358  -0.277  -0.178  -0.592  -0.505  -0.409
41    A        -1.843  -1.763  -1.631  -1.944  -1.838  -1.609  -1.660  -1.568  -1.360
42    H        -2.775  -2.690  -2.424  -2.319  -2.217  -1.869  -1.981  -1.902  -1.603
43    S         0.278   0.353   0.004   0.440   0.531   0.053   0.264   0.371  -0.206
44    L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
45    N        -0.972  -1.180  -1.226  -0.652  -0.960  -1.087  -0.912  -1.150  -1.166
46    Y        -0.366  -0.565  -0.713  -0.128  -0.387  -0.611  -0.378  -0.644  -0.846
47    N         0.954   0.970   1.026   1.071   1.099   1.169   1.012   1.034   1.113
48    T         0.278   0.243  -0.005   0.519   0.477   0.134   0.264   0.210  -0.222
49    P        -0.661  -0.774  -0.761  -0.577  -0.836  -0.846  -0.805  -0.967  -0.913
50    G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
51    G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
52    K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
53    L        -0.366  -0.565  -0.713  -0.434  -0.682  -0.836  -0.378  -0.644  -0.846
54    N         0.954   0.970   1.026   1.071   1.099   1.169   1.012   1.034   1.113
55    R         0.954   0.970   1.026   1.101   1.124   1.196   1.012   1.034   1.113
56    G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
57    L         0.278   0.182  -0.011   0.127   0.019  -0.206   0.264   0.117  -0.232
58    S         0.954   0.970   1.026   1.011   1.033   1.115   1.012   1.034   1.113
59    V         0.954   0.970   1.026   0.975   0.998   1.083   1.012   1.034   1.113
60    V        -0.661  -0.765  -0.750  -0.611  -0.763  -0.742  -0.805  -0.935  -0.899
61    D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
62    T        -0.055  -0.158  -0.105   0.023  -0.168  -0.119  -0.271  -0.460  -0.403
63    Y        -0.366  -0.358  -0.684  -0.160  -0.165  -0.639  -0.378  -0.377  -0.806
64    A        -1.532  -1.661  -1.612  -1.251  -1.461  -1.372  -1.340  -1.461  -1.343
65    I        -0.055  -0.033  -0.086  -0.216  -0.183  -0.353  -0.271  -0.238  -0.368
66    L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
67    S        -1.843  -1.763  -1.631  -1.956  -1.881  -1.611  -1.660  -1.568  -1.360
68    N        -0.233  -0.138  -0.097  -0.312  -0.153  -0.114  -0.592  -0.423  -0.388
69    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
70    K        -0.938  -0.899  -0.790  -1.145  -1.091  -0.934  -1.177  -1.120  -0.947
71    T        -0.253  -0.230  -0.120  -0.326  -0.295  -0.143  -0.630  -0.593  -0.431
72    V        -1.275  -1.290  -1.255  -1.229  -1.302  -1.260  -1.268  -1.286  -1.196
73    E        -2.465  -2.440  -2.196  -2.205  -2.131  -1.820  -1.874  -1.833  -1.543
74    Q        -1.843  -1.713  -1.626  -1.846  -1.628  -1.527  -1.660  -1.536  -1.357
75    L         0.278   0.377   0.003   0.127   0.245  -0.185   0.264   0.405  -0.206
76    G        -2.154  -2.039  -1.929  -2.006  -1.864  -1.683  -1.767  -1.660  -1.462
77    Q        -1.726  -1.618  -1.611  -1.739  -1.624  -1.539  -1.554  -1.455  -1.344
78    E        -0.972  -0.906  -1.187  -0.863  -0.792  -1.185  -0.912  -0.841  -1.124
79    E         0.278   0.165  -0.014   0.278   0.133  -0.142   0.264   0.089  -0.237
80    Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
81    E        -2.037  -2.081  -1.929  -1.873  -1.915  -1.690  -1.660  -1.684  -1.461
82    K        -0.366  -0.496  -0.704  -0.307  -0.469  -0.739  -0.378  -0.551  -0.833
83    V        -0.661  -0.774  -0.761  -0.687  -0.898  -0.923  -0.805  -0.967  -0.913
84    A         0.954   0.970   1.026   0.959   0.985   1.069   1.012   1.034   1.113
85    I        -1.222  -1.312  -1.233  -1.406  -1.506  -1.341  -1.233  -1.304  -1.175
86    L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
87    G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
88    W         0.954   0.970   1.026   1.205   1.227   1.289   1.012   1.034   1.113
89    C        -1.222  -1.226  -1.238  -0.935  -0.988  -1.061  -1.233  -1.253  -1.181
90    I        -0.366  -0.565  -0.713  -0.210  -0.475  -0.706  -0.378  -0.644  -0.846
91    E         0.954   0.970   1.026   0.864   0.889   0.984   1.012   1.034   1.113
92    L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
93    L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
94    Q         0.954   0.970   1.026   1.046   1.071   1.147   1.012   1.034   1.113
95    A         0.278   0.165  -0.014   0.380   0.238  -0.043   0.264   0.089  -0.237
96    Y        -0.233  -0.260  -0.124  -0.358  -0.421  -0.206  -0.592  -0.650  -0.439
97    F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
98    L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
99    V         0.278   0.165  -0.014   0.385   0.236  -0.059   0.264   0.089  -0.237
100   A        -0.055  -0.123  -0.097  -0.087  -0.204  -0.188  -0.271  -0.396  -0.388
101   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
102   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
103   M        -0.233  -0.260  -0.124  -0.260  -0.356  -0.155  -0.592  -0.650  -0.439
104   M         0.954   0.970   1.026   1.157   1.176   1.246   1.012   1.034   1.113
105   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
106   K        -2.154  -2.176  -1.937  -1.992  -2.029  -1.668  -1.767  -1.756  -1.467
107   S         0.954   0.970   1.026   1.011   1.033   1.115   1.012   1.034   1.113
108   I        -0.289  -0.261  -0.124  -0.656  -0.612  -0.380  -0.698  -0.652  -0.439
109   T         0.954   0.970   1.026   1.073   1.092   1.171   1.012   1.034   1.113
110   R         0.954   0.970   1.026   1.101   1.124   1.196   1.012   1.034   1.113
111   R         0.954   0.970   1.026   1.101   1.124   1.196   1.012   1.034   1.113
112   G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
113   Q         0.278   0.182  -0.011   0.440   0.313  -0.038   0.264   0.117  -0.232
114   P         0.954   0.970   1.026   1.138   1.156   1.229   1.012   1.034   1.113
115   C         0.954   0.970   1.026   1.190   1.212   1.276   1.012   1.034   1.113
116   W         0.954   0.970   1.026   1.205   1.227   1.289   1.012   1.034   1.113
117   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
118   K        -0.911  -0.849  -0.778  -1.270  -1.164  -1.022  -1.126  -1.038  -0.932
119   V        -1.532  -1.661  -1.612  -1.240  -1.429  -1.369  -1.340  -1.461  -1.343
120   P        -0.794  -0.723  -0.752  -0.892  -0.798  -0.812  -1.019  -0.944  -0.903
121   E        -1.222  -1.123  -1.217  -1.120  -0.974  -1.168  -1.233  -1.102  -1.158
122   V         0.954   0.970   1.026   0.975   0.998   1.083   1.012   1.034   1.113
123   G        -0.055   0.073  -0.065  -0.012   0.178  -0.058  -0.271  -0.058  -0.329
124   E        -1.415  -1.340  -1.253  -1.359  -1.231  -1.142  -1.447  -1.362  -1.195
125   I         0.278   0.182  -0.011   0.349   0.230  -0.073   0.264   0.117  -0.232
126   A         0.954   0.970   1.026   0.959   0.985   1.069   1.012   1.034   1.113
127   I         0.954   0.970   1.026   0.933   0.960   1.046   1.012   1.034   1.113
128   N         0.954   0.970   1.026   1.071   1.099   1.169   1.012   1.034   1.113
129   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
130   A        -0.055   0.058  -0.051  -0.087   0.086  -0.107  -0.271  -0.083  -0.304
131   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
132   M         0.954   0.970   1.026   1.157   1.176   1.246   1.012   1.034   1.113
133   L         0.278   0.165  -0.014   0.099  -0.043  -0.287   0.264   0.089  -0.237
134   E         0.954   0.970   1.026   0.864   0.889   0.984   1.012   1.034   1.113
135   A        -0.987  -0.890  -0.784  -1.097  -0.943  -0.798  -1.233  -1.100  -0.940
136   A         0.278   0.243  -0.005   0.381   0.342  -0.026   0.264   0.210  -0.222
137   I         0.278   0.353   0.004   0.308   0.410  -0.154   0.264   0.371  -0.206
138   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
139   K        -2.037  -2.011  -1.924  -1.760  -1.734  -1.608  -1.660  -1.628  -1.458
140   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
141   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
142   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
143   S         0.278   0.370   0.001   0.239   0.356  -0.135   0.264   0.396  -0.210
144   H         0.278   0.182  -0.011   0.614   0.489   0.152   0.264   0.117  -0.232
145   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
146   R         0.954   0.970   1.026   1.101   1.124   1.196   1.012   1.034   1.113
147   N        -1.298  -1.283  -1.231  -1.138  -1.115  -1.025  -1.340  -1.304  -1.175
148   E        -0.661  -0.642  -0.725  -0.732  -0.661  -0.788  -0.805  -0.753  -0.864
149   K        -0.987  -0.968  -0.793  -1.118  -1.090  -0.824  -1.233  -1.198  -0.952
150   Y        -0.366  -0.565  -0.713  -0.109  -0.359  -0.566  -0.378  -0.644  -0.846
151   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
152   I        -0.055  -0.026  -0.085  -0.096  -0.054  -0.193  -0.271  -0.225  -0.366
153   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
154   I        -0.366  -0.382  -0.692  -0.476  -0.498  -0.907  -0.378  -0.405  -0.818
155   T        -0.972  -1.037  -1.203  -1.026  -1.128  -1.306  -0.912  -0.989  -1.142
156   E        -0.055   0.058  -0.051  -0.228  -0.046  -0.251  -0.271  -0.083  -0.304
157   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
158   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
159   H         0.954   0.970   1.026   1.197   1.218   1.282   1.012   1.034   1.113
160   E        -0.289  -0.261  -0.124  -0.677  -0.629  -0.397  -0.698  -0.651  -0.438
161   V         0.278   0.243  -0.005   0.385   0.341  -0.043   0.264   0.210  -0.222
162   T         0.278   0.243  -0.005   0.493   0.447   0.067   0.264   0.210  -0.222
163   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
164   Q         0.278   0.243  -0.005   0.440   0.397  -0.027   0.264   0.210  -0.222
165   T         0.954   0.970   1.026   1.073   1.092   1.171   1.012   1.034   1.113
166   E         0.954   0.970   1.026   0.864   0.889   0.984   1.012   1.034   1.113
167   L         0.278   0.182  -0.011   0.127   0.019  -0.206   0.264   0.117  -0.232
168   G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
169   Q         0.954   0.970   1.026   1.046   1.071   1.147   1.012   1.034   1.113
170   L         0.278   0.165  -0.014   0.110  -0.027  -0.257   0.264   0.089  -0.237
171   M        -1.532  -1.528  -1.594  -1.477  -1.469  -1.469  -1.340  -1.329  -1.328
172   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
173   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
174   I        -0.233  -0.260  -0.124  -0.589  -0.695  -0.467  -0.592  -0.650  -0.439
175   T         0.954   0.970   1.026   1.073   1.092   1.171   1.012   1.034   1.113
176   A         0.954   0.970   1.026   0.959   0.985   1.069   1.012   1.034   1.113
177   P        -0.055   0.058  -0.051   0.039   0.217  -0.027  -0.271  -0.083  -0.304
178   E         0.954   0.970   1.026   0.864   0.889   0.984   1.012   1.034   1.113
179   D        -0.055   0.058  -0.051  -0.230  -0.047  -0.252  -0.271  -0.083  -0.304
180   K        -1.726  -1.710  -1.613  -1.717  -1.700  -1.504  -1.554  -1.516  -1.344
181   V         0.954   0.970   1.026   0.975   0.998   1.083   1.012   1.034   1.113
182   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
183   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
184   S        -0.794  -0.801  -0.755  -0.893  -0.892  -0.796  -1.019  -1.010  -0.906
185   K        -0.366  -0.496  -0.704  -0.303  -0.463  -0.730  -0.378  -0.551  -0.833
186   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
187   S         0.954   0.970   1.026   1.011   1.033   1.115   1.012   1.034   1.113
188   L         0.278   0.182  -0.011   0.127   0.019  -0.206   0.264   0.117  -0.232
189   K        -1.843  -1.796  -1.630  -1.927  -1.846  -1.605  -1.660  -1.597  -1.359
190   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
191   H         0.278   0.182  -0.011   0.614   0.489   0.152   0.264   0.117  -0.232
192   S         0.278   0.182  -0.011   0.441   0.321   0.029   0.264   0.117  -0.232
193   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
194   I         0.954   0.970   1.026   0.933   0.960   1.046   1.012   1.034   1.113
195   V         0.954   0.970   1.026   0.975   0.998   1.083   1.012   1.034   1.113
196   T        -0.366  -0.326  -0.686  -0.188  -0.139  -0.617  -0.378  -0.326  -0.810
197   F        -0.289  -0.238  -0.116  -0.464  -0.381  -0.193  -0.698  -0.609  -0.424
198   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
199   T         0.954   0.970   1.026   1.073   1.092   1.171   1.012   1.034   1.113
200   A         0.954   0.970   1.026   0.959   0.985   1.069   1.012   1.034   1.113
201   Y         0.278   0.165  -0.014   0.417   0.272  -0.009   0.264   0.089  -0.237
202   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
203   S         0.954   0.970   1.026   1.011   1.033   1.115   1.012   1.034   1.113
204   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
205   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
206   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
207   P         0.278   0.356   0.001   0.551   0.643   0.113   0.264   0.376  -0.211
208   V         0.954   0.970   1.026   0.975   0.998   1.083   1.012   1.034   1.113
209   A         0.278   0.243  -0.005   0.375   0.335  -0.041   0.264   0.210  -0.222
210   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
211   A         0.954   0.970   1.026   0.959   0.985   1.069   1.012   1.034   1.113
212   M         0.954   0.970   1.026   1.157   1.176   1.246   1.012   1.034   1.113
213   Y        -0.661  -0.689  -0.735  -0.549  -0.562  -0.637  -0.805  -0.819  -0.878
214   V        -1.415  -1.418  -1.254  -1.381  -1.401  -1.206  -1.447  -1.422  -1.196
215   A        -0.661  -0.655  -0.724  -0.682  -0.670  -0.839  -0.805  -0.771  -0.862
216   G         0.278   0.182  -0.011   0.416   0.287  -0.048   0.264   0.117  -0.232
217   I        -0.055  -0.071  -0.094  -0.123  -0.153  -0.221  -0.271  -0.303  -0.383
218   T        -0.987  -0.981  -0.795  -1.019  -1.029  -0.755  -1.233  -1.214  -0.954
219   D        -1.222  -1.255  -1.240  -1.169  -1.217  -1.145  -1.233  -1.277  -1.183
220   E        -0.987  -0.893  -0.784  -1.088  -0.908  -0.773  -1.233  -1.102  -0.940
221   K        -0.661  -0.691  -0.750  -0.805  -0.899  -0.922  -0.805  -0.876  -0.898
222   D        -0.055  -0.158  -0.105  -0.162  -0.324  -0.242  -0.271  -0.460  -0.403
223   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
224   K         0.278   0.243  -0.005   0.244   0.209  -0.131   0.264   0.210  -0.222
225   Q         0.278   0.165  -0.014   0.493   0.360   0.099   0.264   0.089  -0.237
226   A        -0.055   0.058  -0.051  -0.098   0.077  -0.122  -0.271  -0.083  -0.304
227   R        -1.726  -1.754  -1.621  -1.438  -1.500  -1.318  -1.554  -1.562  -1.352
228   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
229   V        -0.289  -0.257  -0.123  -0.541  -0.491  -0.273  -0.698  -0.644  -0.436
230   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
231   I         0.954   0.970   1.026   0.933   0.960   1.046   1.012   1.034   1.113
232   P         0.278   0.165  -0.014   0.547   0.393   0.076   0.264   0.089  -0.237
233   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
234   G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
235   E         0.278   0.165  -0.014   0.257   0.105  -0.198   0.264   0.089  -0.237
236   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
237   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
238   Q         0.954   0.970   1.026   1.046   1.071   1.147   1.012   1.034   1.113
239   I        -0.233  -0.260  -0.124  -0.435  -0.496  -0.276  -0.592  -0.650  -0.439
240   Q         0.954   0.970   1.026   1.046   1.071   1.147   1.012   1.034   1.113
241   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
242   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
243   Y        -0.055   0.034  -0.074  -0.049   0.085  -0.115  -0.271  -0.124  -0.346
244   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
245   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
246   C        -0.055  -0.123  -0.097   0.153   0.032   0.015  -0.271  -0.396  -0.388
247   F         0.278   0.165  -0.014   0.438   0.291   0.001   0.264   0.089  -0.237
248   G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
249   T        -1.222  -1.278  -1.242  -1.203  -1.363  -1.361  -1.233  -1.298  -1.184
250   P         0.954   0.970   1.026   1.138   1.156   1.229   1.012   1.034   1.113
251   E         0.278   0.165  -0.014   0.294   0.155  -0.096   0.264   0.089  -0.237
252   Q        -1.532  -1.659  -1.614  -1.182  -1.366  -1.344  -1.340  -1.459  -1.345
253   I         0.278   0.165  -0.014   0.364   0.225  -0.039   0.264   0.089  -0.237
254   G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
255   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
256   I         0.954   0.970   1.026   0.933   0.960   1.046   1.012   1.034   1.113
257   G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
258   T         0.954   0.970   1.026   1.073   1.092   1.171   1.012   1.034   1.113
259   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
260   I         0.954   0.970   1.026   0.933   0.960   1.046   1.012   1.034   1.113
261   Q        -0.661  -0.669  -0.727  -0.671  -0.670  -0.866  -0.805  -0.790  -0.866
262   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
263   N         0.954   0.970   1.026   1.071   1.099   1.169   1.012   1.034   1.113
264   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
265   C         0.954   0.970   1.026   1.190   1.212   1.276   1.012   1.034   1.113
266   S         0.954   0.970   1.026   1.011   1.033   1.115   1.012   1.034   1.113
267   W         0.954   0.970   1.026   1.205   1.227   1.289   1.012   1.034   1.113
268   V        -0.911  -0.950  -0.794  -1.146  -1.263  -1.025  -1.126  -1.174  -0.952
269   I        -0.233  -0.237  -0.121  -0.435  -0.452  -0.271  -0.592  -0.605  -0.433
270   N         0.954   0.970   1.026   1.071   1.099   1.169   1.012   1.034   1.113
271   K        -1.222  -1.184  -1.220  -1.318  -1.281  -1.335  -1.233  -1.169  -1.160
272   A         0.954   0.970   1.026   0.959   0.985   1.069   1.012   1.034   1.113
273   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
274   E        -2.154  -2.175  -1.941  -2.290  -2.271  -1.919  -1.767  -1.755  -1.469
275   L        -1.843  -1.744  -1.626  -1.985  -1.846  -1.584  -1.660  -1.559  -1.356
276   A        -0.366  -0.565  -0.713  -0.165  -0.420  -0.640  -0.378  -0.644  -0.846
277   S        -0.661  -0.505  -0.723  -0.493  -0.275  -0.605  -0.805  -0.588  -0.861
278   A        -1.222  -1.038  -1.212  -1.081  -0.793  -1.136  -1.233  -1.009  -1.153
279   E         0.278   0.377   0.003   0.257   0.385  -0.166   0.264   0.405  -0.206
280   Q         0.954   0.970   1.026   1.046   1.071   1.147   1.012   1.034   1.113
281   R         0.954   0.970   1.026   1.101   1.124   1.196   1.012   1.034   1.113
282   K        -1.222  -1.229  -1.222  -1.278  -1.283  -1.262  -1.233  -1.228  -1.164
283   T        -0.911  -0.842  -0.770  -1.120  -0.990  -0.912  -1.126  -1.029  -0.922
284   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
285   D        -0.055  -0.123  -0.097  -0.230  -0.355  -0.342  -0.271  -0.396  -0.388
286   E        -0.233  -0.233  -0.120  -0.559  -0.571  -0.389  -0.592  -0.599  -0.432
287   N         0.954   0.970   1.026   1.071   1.099   1.169   1.012   1.034   1.113
288   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
289   G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
290   K        -0.794  -0.760  -0.747  -0.863  -0.762  -0.769  -1.019  -0.944  -0.894
291   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
292   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
293   S        -0.911  -0.879  -0.775  -1.089  -1.058  -0.928  -1.126  -1.083  -0.928
294   V        -1.532  -1.511  -1.596  -1.428  -1.406  -1.551  -1.340  -1.313  -1.330
295   A        -1.298  -1.173  -1.228  -1.324  -1.186  -1.163  -1.340  -1.211  -1.172
296   E         0.954   0.970   1.026   0.864   0.889   0.984   1.012   1.034   1.113
297   A        -1.415  -1.391  -1.251  -1.571  -1.555  -1.363  -1.447  -1.401  -1.194
298   K        -1.415  -1.372  -1.257  -1.470  -1.406  -1.187  -1.447  -1.400  -1.200
299   C        -0.661  -0.807  -0.761  -0.441  -0.692  -0.678  -0.805  -0.995  -0.912
300   K         0.278   0.356   0.001   0.252   0.351  -0.100   0.264   0.376  -0.211
301   K        -1.415  -1.335  -1.253  -1.526  -1.413  -1.291  -1.447  -1.362  -1.195
302   I        -0.794  -0.715  -0.752  -1.123  -1.022  -0.995  -1.019  -0.925  -0.903
303   F        -0.055  -0.123  -0.097  -0.033  -0.157  -0.151  -0.271  -0.396  -0.388
304   N        -1.843  -1.794  -1.632  -1.914  -1.859  -1.594  -1.660  -1.595  -1.361
305   D        -0.794  -0.695  -0.748  -1.022  -0.901  -0.894  -1.019  -0.907  -0.898
306   L         0.278   0.243  -0.005   0.127   0.092  -0.197   0.264   0.210  -0.222
307   K        -0.794  -0.699  -0.748  -0.932  -0.814  -0.810  -1.019  -0.912  -0.899
308   I         0.278   0.182  -0.011   0.308   0.176  -0.185   0.264   0.117  -0.232
309   E        -0.972  -0.940  -1.196  -0.839  -0.797  -1.154  -0.912  -0.878  -1.135
310   Q        -1.843  -1.807  -1.627  -1.906  -1.838  -1.567  -1.660  -1.608  -1.357
311   L        -1.726  -1.752  -1.620  -1.655  -1.695  -1.555  -1.554  -1.561  -1.351
312   Y         0.278   0.165  -0.014   0.417   0.272  -0.009   0.264   0.089  -0.237
313   H        -2.037  -2.078  -1.928  -1.696  -1.857  -1.687  -1.660  -1.681  -1.460
314   E        -1.726  -1.753  -1.620  -1.761  -1.761  -1.577  -1.554  -1.554  -1.351
315   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
316   E         0.954   0.970   1.026   0.864   0.889   0.984   1.012   1.034   1.113
317   E         0.954   0.970   1.026   0.864   0.889   0.984   1.012   1.034   1.113
318   S        -1.298  -1.184  -1.224  -1.372  -1.231  -1.251  -1.340  -1.220  -1.169
319   I        -1.843  -1.870  -1.630  -1.746  -1.779  -1.439  -1.660  -1.651  -1.359
320   A        -0.794  -0.679  -0.742  -0.874  -0.697  -0.761  -1.019  -0.858  -0.888
321   K        -1.843  -1.728  -1.628  -1.766  -1.608  -1.460  -1.660  -1.549  -1.357
322   D        -1.415  -1.301  -1.243  -1.646  -1.464  -1.345  -1.447  -1.312  -1.185
323   L        -0.233  -0.260  -0.124  -0.680  -0.716  -0.469  -0.592  -0.650  -0.439
324   K        -0.289  -0.261  -0.124  -0.530  -0.493  -0.269  -0.698  -0.652  -0.438
325   A        -0.972  -0.765  -1.182  -0.953  -0.669  -1.296  -0.912  -0.661  -1.119
326   K        -1.222  -1.304  -1.234  -1.274  -1.390  -1.277  -1.233  -1.294  -1.175
327   I         0.954   0.970   1.026   0.933   0.960   1.046   1.012   1.034   1.113
328   S        -1.415  -1.306  -1.244  -1.573  -1.419  -1.303  -1.447  -1.318  -1.186
329   Q        -0.972  -1.094  -1.211  -0.654  -0.840  -1.035  -0.912  -1.057  -1.150
330   V        -0.289  -0.261  -0.124  -0.541  -0.496  -0.274  -0.698  -0.652  -0.438
331   D         0.954   0.970   1.026   0.860   0.888   0.980   1.012   1.034   1.113
332   E         0.954   0.970   1.026   0.864   0.889   0.984   1.012   1.034   1.113
333   S         0.954   0.970   1.026   1.011   1.033   1.115   1.012   1.034   1.113
334   R        -0.366  -0.565  -0.713  -0.069  -0.350  -0.641  -0.378  -0.644  -0.846
335   G         0.954   0.970   1.026   1.016   1.038   1.120   1.012   1.034   1.113
336   F        -0.289  -0.257  -0.123  -0.688  -0.655  -0.414  -0.698  -0.644  -0.436
337   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
338   A        -0.055   0.045  -0.067  -0.241  -0.083  -0.271  -0.271  -0.105  -0.332
339   D        -1.222  -1.297  -1.229  -1.270  -1.344  -1.249  -1.233  -1.286  -1.170
340   V         0.278   0.165  -0.014   0.385   0.236  -0.059   0.264   0.089  -0.237
341   L        -0.055  -0.158  -0.105  -0.350  -0.514  -0.402  -0.271  -0.460  -0.403
342   T        -0.366  -0.496  -0.704  -0.090  -0.275  -0.629  -0.378  -0.551  -0.833
343   A        -0.972  -0.960  -1.193  -0.792  -0.776  -1.170  -0.912  -0.900  -1.131
344   F         0.954   0.970   1.026   1.020   1.042   1.123   1.012   1.034   1.113
345   L         0.954   0.970   1.026   0.684   0.711   0.822   1.012   1.034   1.113
346   N        -0.794  -0.815  -0.756  -0.773  -0.807  -0.716  -1.019  -1.033  -0.908
347   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
348   V        -0.289  -0.239  -0.117  -0.541  -0.457  -0.263  -0.698  -0.610  -0.424
349   Y         0.954   0.970   1.026   0.995   1.018   1.101   1.012   1.034   1.113
350   K         0.278   0.356   0.001   0.267   0.364  -0.062   0.264   0.376  -0.211
351   R         0.954   0.970   1.026   1.101   1.124   1.196   1.012   1.034   1.113
352   S        -0.972  -1.048  -1.202  -0.709  -0.815  -1.085  -0.912  -1.002  -1.140
353   K         0.954   0.970   1.026   0.818   0.846   0.942   1.012   1.034   1.113
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P08524
Output conservation file - output/P08524
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
