1     M         1.175   1.200   1.266   1.312   1.346   1.440   1.257   1.291   1.388
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    T        -0.373  -0.242  -0.484  -0.251  -0.076  -0.421  -0.459  -0.272  -0.608
20    A        -1.201  -1.158  -1.079  -1.233  -1.185  -1.060  -1.214  -1.156  -1.027
21    E        -0.707  -0.626  -0.582  -0.960  -0.834  -0.748  -0.940  -0.830  -0.744
22    E        -0.680  -0.601  -0.587  -1.007  -0.857  -0.894  -0.888  -0.768  -0.748
23    F         0.371   0.202   0.184   0.410   0.136   0.059   0.304   0.020  -0.048
24    D         0.107   0.021   0.103   0.021  -0.147  -0.028  -0.144  -0.307  -0.198
25    F        -0.530  -0.635  -0.562  -0.623  -0.802  -0.718  -0.704  -0.828  -0.720
26    S        -0.530  -0.628  -0.559  -0.563  -0.721  -0.621  -0.704  -0.820  -0.717
27    S        -1.103  -0.945  -1.037  -1.113  -0.856  -1.023  -1.124  -0.925  -0.984
28    H        -0.530  -0.515  -0.554  -0.432  -0.441  -0.476  -0.704  -0.711  -0.709
29    S         0.443   0.331   0.228   0.477   0.327   0.157   0.417   0.237   0.032
30    H         1.175   1.200   1.266   1.253   1.296   1.385   1.257   1.291   1.388
31    R         0.443   0.496   0.238   0.564   0.627   0.255   0.417   0.496   0.050
32    R         1.175   1.200   1.266   1.215   1.244   1.350   1.257   1.291   1.388
33    Y        -0.246  -0.072  -0.458  -0.105   0.144  -0.459  -0.284  -0.043  -0.573
34    N         1.175   1.200   1.266   1.181   1.225   1.317   1.257   1.291   1.388
35    P         0.443   0.556   0.243   0.450   0.601   0.121   0.417   0.585   0.058
36    L         1.175   1.200   1.266   0.954   1.008   1.105   1.257   1.291   1.388
37    T        -0.883  -0.990  -1.027  -0.704  -0.870  -0.937  -0.844  -0.963  -0.972
38    D        -1.103  -1.182  -1.059  -1.040  -1.118  -0.954  -1.124  -1.174  -1.008
39    S        -0.246  -0.072  -0.458  -0.165   0.071  -0.492  -0.284  -0.043  -0.573
40    W        -0.530  -0.360  -0.521  -0.376  -0.115  -0.374  -0.704  -0.460  -0.661
41    I        -0.530  -0.572  -0.552  -0.578  -0.648  -0.641  -0.704  -0.735  -0.705
42    L         1.175   1.200   1.266   0.954   1.008   1.105   1.257   1.291   1.388
43    V        -0.043   0.042   0.110  -0.170  -0.048   0.064  -0.424  -0.270  -0.185
44    S         1.175   1.200   1.266   1.130   1.168   1.270   1.257   1.291   1.388
45    P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
46    H         1.175   1.200   1.266   1.253   1.296   1.385   1.257   1.291   1.388
47    R         1.175   1.200   1.266   1.215   1.244   1.350   1.257   1.291   1.388
48    A         0.443   0.348   0.225   0.500   0.363   0.183   0.417   0.265   0.026
49    K         1.175   1.200   1.266   1.080   1.127   1.223   1.257   1.291   1.388
50    R         1.175   1.200   1.266   1.215   1.244   1.350   1.257   1.291   1.388
51    P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
52    W         1.175   1.200   1.266   1.340   1.372   1.466   1.257   1.291   1.388
53    L         0.107   0.164   0.135  -0.016   0.086  -0.034  -0.144  -0.047  -0.139
54    G         1.175   1.200   1.266   1.238   1.285   1.371   1.257   1.291   1.388
55    Q        -0.043   0.042   0.110  -0.233  -0.081   0.011  -0.424  -0.270  -0.185
56    Q        -0.043   0.042   0.110  -0.273  -0.102  -0.025  -0.424  -0.270  -0.185
57    E         1.175   1.200   1.266   1.052   1.081   1.197   1.257   1.291   1.388
58    A        -0.530  -0.518  -0.555  -0.693  -0.696  -0.731  -0.704  -0.690  -0.711
59    A        -1.103  -0.951  -1.037  -1.127  -0.890  -1.045  -1.124  -0.928  -0.984
60    Y        -1.456  -1.534  -1.454  -1.332  -1.442  -1.312  -1.265  -1.321  -1.188
61    K        -0.246  -0.303  -0.486  -0.232  -0.312  -0.615  -0.284  -0.360  -0.611
62    P        -1.236  -1.183  -1.076  -1.307  -1.212  -1.058  -1.265  -1.189  -1.026
63    T        -1.103  -1.109  -1.055  -1.103  -1.127  -1.037  -1.124  -1.119  -1.005
64    A        -1.103  -1.087  -1.049  -1.297  -1.269  -1.185  -1.124  -1.088  -0.998
65    P         0.443   0.558   0.244   0.483   0.626   0.194   0.417   0.588   0.061
66    L        -1.456  -1.283  -1.411  -1.496  -1.222  -1.456  -1.265  -1.067  -1.150
67    Y        -0.246  -0.128  -0.461  -0.047   0.119  -0.359  -0.284  -0.118  -0.577
68    D         1.175   1.200   1.266   1.171   1.210   1.308   1.257   1.291   1.388
69    P         0.107   0.076   0.113  -0.009  -0.071  -0.031  -0.144  -0.206  -0.180
70    K        -0.246  -0.248  -0.474  -0.189  -0.186  -0.511  -0.284  -0.291  -0.594
71    C         1.175   1.200   1.266   1.321   1.357   1.449   1.257   1.291   1.388
72    Y         1.175   1.200   1.266   1.210   1.253   1.344   1.257   1.291   1.388
73    L         1.175   1.200   1.266   0.954   1.008   1.105   1.257   1.291   1.388
74    C         1.175   1.200   1.266   1.321   1.357   1.449   1.257   1.291   1.388
75    P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
76    G         0.443   0.331   0.228   0.598   0.461   0.282   0.417   0.237   0.032
77    N         0.443   0.496   0.238   0.535   0.614   0.236   0.417   0.496   0.050
78    K        -1.103  -1.148  -1.063  -1.061  -1.147  -1.022  -1.124  -1.153  -1.013
79    R         1.175   1.200   1.266   1.215   1.244   1.350   1.257   1.291   1.388
80    A         0.443   0.331   0.228   0.513   0.358   0.216   0.417   0.237   0.032
81    T        -0.246  -0.443  -0.503  -0.091  -0.371  -0.476  -0.284  -0.548  -0.635
82    G         1.175   1.200   1.266   1.238   1.285   1.371   1.257   1.291   1.388
83    N        -1.103  -1.024  -1.046  -1.128  -1.039  -1.034  -1.124  -1.035  -0.996
84    L        -1.590  -1.498  -1.442  -1.527  -1.379  -1.331  -1.405  -1.303  -1.179
85    N         1.175   1.200   1.266   1.181   1.225   1.317   1.257   1.291   1.388
86    P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
87    R        -1.103  -1.140  -1.065  -1.115  -1.142  -1.014  -1.124  -1.145  -1.014
88    Y         1.175   1.200   1.266   1.210   1.253   1.344   1.257   1.291   1.388
89    E        -0.530  -0.516  -0.556  -0.703  -0.727  -0.736  -0.704  -0.712  -0.712
90    S        -1.590  -1.532  -1.449  -1.525  -1.440  -1.310  -1.405  -1.333  -1.185
91    T         1.175   1.200   1.266   1.179   1.208   1.316   1.257   1.291   1.388
92    Y         0.107   0.021   0.103   0.077  -0.076   0.031  -0.144  -0.307  -0.198
93    I        -0.617  -0.653  -0.558  -0.674  -0.729  -0.573  -0.844  -0.858  -0.717
94    F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
95    P        -0.883  -1.023  -1.035  -0.783  -1.020  -1.042  -0.844  -0.998  -0.980
96    N         1.175   1.200   1.266   1.181   1.225   1.317   1.257   1.291   1.388
97    D         0.443   0.496   0.238   0.535   0.612   0.249   0.417   0.496   0.050
98    Y         0.443   0.331   0.228   0.568   0.429   0.254   0.417   0.237   0.032
99    A        -0.530  -0.556  -0.560  -0.611  -0.688  -0.663  -0.704  -0.754  -0.717
100   A         1.175   1.200   1.266   1.146   1.169   1.285   1.257   1.291   1.388
101   V         1.175   1.200   1.266   1.154   1.177   1.292   1.257   1.291   1.388
102   R        -0.530  -0.635  -0.562  -0.544  -0.711  -0.615  -0.704  -0.828  -0.720
103   L        -0.750  -0.717  -0.597  -1.132  -1.085  -0.883  -0.984  -0.933  -0.762
104   D        -0.530  -0.635  -0.562  -0.626  -0.803  -0.712  -0.704  -0.828  -0.720
105   Q         0.443   0.331   0.228   0.564   0.413   0.244   0.417   0.237   0.032
106   P        -0.246  -0.443  -0.503  -0.143  -0.427  -0.527  -0.284  -0.548  -0.635
107   I        -0.617  -0.554  -0.553  -0.780  -0.700  -0.646  -0.844  -0.751  -0.710
108   L        -0.883  -0.916  -1.017  -0.742  -0.789  -1.009  -0.844  -0.874  -0.961
109   P        -1.943  -1.835  -1.767  -1.769  -1.623  -1.501  -1.545  -1.432  -1.300
110   Q        -1.590  -1.626  -1.461  -1.672  -1.721  -1.494  -1.405  -1.405  -1.194
111   N        -1.456  -1.534  -1.454  -1.263  -1.390  -1.274  -1.265  -1.321  -1.188
112   D        -1.590  -1.546  -1.453  -1.620  -1.556  -1.400  -1.405  -1.339  -1.188
113   -        -1.201  -1.128  -1.068  -1.302  -1.201  -1.093  -1.214  -1.118  -1.015
114   -         0.172   0.146   0.143  -0.008  -0.062  -0.071  -0.030  -0.079  -0.124
115   -        -0.062  -0.021   0.089  -0.239  -0.190  -0.008  -0.459  -0.387  -0.224
116   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   S        -1.236  -1.174  -1.077  -1.332  -1.240  -1.091  -1.265  -1.185  -1.026
121   N        -1.103  -1.202  -1.071  -1.160  -1.278  -1.093  -1.124  -1.198  -1.020
122   E        -1.943  -1.858  -1.766  -1.725  -1.609  -1.469  -1.545  -1.450  -1.300
123   D        -1.103  -1.063  -1.046  -1.078  -1.000  -0.988  -1.124  -1.054  -0.993
124   N        -1.590  -1.546  -1.453  -1.520  -1.463  -1.316  -1.405  -1.339  -1.188
125   L         0.443   0.348   0.225   0.322   0.223   0.043   0.417   0.265   0.026
126   K        -0.246  -0.443  -0.503  -0.203  -0.473  -0.586  -0.284  -0.548  -0.635
127   N        -1.943  -1.870  -1.765  -1.915  -1.829  -1.670  -1.545  -1.460  -1.299
128   R        -0.883  -0.990  -1.027  -0.745  -0.929  -1.038  -0.844  -0.963  -0.972
129   L         0.443   0.558   0.244   0.332   0.491   0.095   0.417   0.588   0.061
130   L        -0.043   0.024   0.100  -0.406  -0.286  -0.170  -0.424  -0.302  -0.203
131   K        -0.530  -0.621  -0.556  -0.607  -0.720  -0.622  -0.704  -0.806  -0.712
132   V        -1.456  -1.534  -1.454  -1.375  -1.523  -1.439  -1.265  -1.321  -1.188
133   Q        -0.530  -0.508  -0.541  -0.591  -0.573  -0.641  -0.704  -0.673  -0.692
134   S        -0.883  -1.020  -1.031  -0.669  -0.874  -0.937  -0.844  -0.995  -0.976
135   V         0.443   0.348   0.225   0.503   0.362   0.178   0.417   0.265   0.026
136   R        -1.103  -1.192  -1.060  -1.114  -1.218  -1.021  -1.124  -1.186  -1.009
137   G         1.175   1.200   1.266   1.238   1.285   1.371   1.257   1.291   1.388
138   N        -1.103  -1.202  -1.071  -1.122  -1.225  -1.037  -1.124  -1.198  -1.020
139   C         1.175   1.200   1.266   1.321   1.357   1.449   1.257   1.291   1.388
140   F        -0.530  -0.635  -0.562  -0.494  -0.645  -0.545  -0.704  -0.828  -0.720
141   V         1.175   1.200   1.266   1.154   1.177   1.292   1.257   1.291   1.388
142   I         0.443   0.348   0.225   0.571   0.439   0.195   0.417   0.265   0.026
143   C         0.443   0.348   0.225   0.674   0.548   0.336   0.417   0.265   0.026
144   F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
145   S         0.443   0.558   0.244   0.509   0.652   0.253   0.417   0.588   0.061
146   P         0.443   0.348   0.225   0.481   0.351   0.159   0.417   0.265   0.026
147   N        -0.043   0.025   0.102  -0.318  -0.188  -0.086  -0.424  -0.300  -0.201
148   H         1.175   1.200   1.266   1.253   1.296   1.385   1.257   1.291   1.388
149   N         0.443   0.348   0.225   0.534   0.419   0.211   0.417   0.265   0.026
150   L        -0.246  -0.443  -0.503  -0.326  -0.587  -0.682  -0.284  -0.548  -0.635
151   T         0.443   0.496   0.238   0.525   0.590   0.217   0.417   0.496   0.050
152   I        -0.246  -0.167  -0.475  -0.299  -0.174  -0.590  -0.284  -0.170  -0.596
153   P         0.107   0.021   0.103  -0.019  -0.191  -0.063  -0.144  -0.307  -0.198
154   Q        -1.103  -1.202  -1.071  -1.232  -1.334  -1.130  -1.124  -1.198  -1.020
155   M         1.175   1.200   1.266   1.312   1.346   1.440   1.257   1.291   1.388
156   K        -1.103  -1.111  -1.050  -1.165  -1.156  -1.072  -1.124  -1.105  -0.999
157   Q        -1.236  -1.167  -1.076  -1.279  -1.203  -1.034  -1.265  -1.180  -1.026
158   S        -1.103  -1.078  -1.054  -1.176  -1.144  -1.065  -1.124  -1.078  -1.002
159   D        -1.103  -1.075  -1.042  -1.170  -1.128  -1.053  -1.124  -1.072  -0.991
160   L         0.443   0.500   0.237   0.571   0.654   0.218   0.417   0.502   0.047
161   V        -1.943  -1.844  -1.764  -1.688  -1.591  -1.433  -1.545  -1.440  -1.299
162   H        -1.456  -1.508  -1.441  -1.294  -1.385  -1.302  -1.265  -1.299  -1.176
163   I         0.443   0.500   0.237   0.521   0.584   0.237   0.417   0.502   0.047
164   V        -0.043  -0.034   0.084  -0.212  -0.204  -0.010  -0.424  -0.412  -0.235
165   N        -1.103  -0.975  -1.035  -1.183  -0.995  -1.065  -1.124  -0.961  -0.984
166   S        -0.530  -0.388  -0.527  -0.568  -0.361  -0.569  -0.704  -0.504  -0.671
167   W         1.175   1.200   1.266   1.340   1.372   1.466   1.257   1.291   1.388
168   Q        -1.103  -0.994  -1.039  -1.051  -0.913  -0.961  -1.124  -1.004  -0.989
169   A        -2.296  -2.229  -2.053  -2.049  -1.957  -1.708  -1.685  -1.608  -1.394
170   L        -0.246  -0.443  -0.503  -0.276  -0.510  -0.584  -0.284  -0.548  -0.635
171   T        -0.246  -0.167  -0.475  -0.062   0.053  -0.408  -0.284  -0.170  -0.596
172   D        -2.296  -2.229  -2.053  -2.049  -1.958  -1.708  -1.685  -1.608  -1.394
173   D        -1.590  -1.605  -1.456  -1.543  -1.586  -1.353  -1.405  -1.390  -1.190
174   L        -0.246  -0.443  -0.503  -0.311  -0.563  -0.654  -0.284  -0.548  -0.635
175   S        -1.590  -1.498  -1.443  -1.708  -1.554  -1.486  -1.405  -1.302  -1.180
176   R        -1.103  -1.037  -1.056  -1.150  -1.067  -1.048  -1.124  -1.052  -1.006
177   E        -0.246  -0.443  -0.503  -0.222  -0.508  -0.590  -0.284  -0.548  -0.635
178   A        -0.617  -0.666  -0.561  -0.746  -0.797  -0.623  -0.844  -0.875  -0.720
179   R        -1.609  -1.574  -1.461  -1.632  -1.560  -1.374  -1.412  -1.360  -1.194
180   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
181   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
182   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
183   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
184   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
185   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
186   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
187   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
188   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
189   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
190   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
191   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
195   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
196   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
202   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
203   E        -1.041  -1.036  -1.052  -1.050  -1.067  -1.062  -1.031  -1.021  -0.998
204   N        -1.609  -1.602  -1.470  -1.538  -1.544  -1.367  -1.412  -1.383  -1.201
205   H        -1.609  -1.602  -1.470  -1.513  -1.511  -1.305  -1.412  -1.383  -1.201
206   K        -1.609  -1.546  -1.465  -1.535  -1.442  -1.312  -1.412  -1.336  -1.197
207   P        -1.041  -1.031  -1.050  -0.989  -0.983  -1.014  -1.031  -1.016  -0.996
208   F        -0.883  -1.020  -1.031  -0.701  -0.909  -0.964  -0.844  -0.995  -0.976
209   K         0.443   0.348   0.225   0.440   0.330   0.139   0.417   0.265   0.026
210   Y         1.175   1.200   1.266   1.210   1.253   1.344   1.257   1.291   1.388
211   V        -0.883  -1.020  -1.031  -0.904  -1.076  -1.079  -0.844  -0.995  -0.976
212   Q         0.443   0.331   0.228   0.527   0.367   0.162   0.417   0.237   0.032
213   I         1.175   1.200   1.266   1.253   1.290   1.385   1.257   1.291   1.388
214   F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
215   E         1.175   1.200   1.266   1.052   1.081   1.197   1.257   1.291   1.388
216   N         1.175   1.200   1.266   1.181   1.225   1.317   1.257   1.291   1.388
217   K         0.443   0.543   0.241   0.440   0.579   0.165   0.417   0.566   0.055
218   G         1.175   1.200   1.266   1.238   1.285   1.371   1.257   1.291   1.388
219   T        -1.103  -0.951  -1.036  -1.093  -0.890  -0.983  -1.124  -0.944  -0.985
220   A         0.443   0.331   0.228   0.500   0.339   0.188   0.417   0.237   0.032
221   M         1.175   1.200   1.266   1.312   1.346   1.440   1.257   1.291   1.388
222   G         1.175   1.200   1.266   1.238   1.285   1.371   1.257   1.291   1.388
223   C         1.175   1.200   1.266   1.321   1.357   1.449   1.257   1.291   1.388
224   S         1.175   1.200   1.266   1.130   1.168   1.270   1.257   1.291   1.388
225   N         1.175   1.200   1.266   1.181   1.225   1.317   1.257   1.291   1.388
226   L         0.107   0.164   0.135  -0.091   0.009  -0.100  -0.144  -0.047  -0.139
227   H         1.175   1.200   1.266   1.253   1.296   1.385   1.257   1.291   1.388
228   P         0.443   0.331   0.228   0.481   0.326   0.164   0.417   0.237   0.032
229   H         1.175   1.200   1.266   1.253   1.296   1.385   1.257   1.291   1.388
230   G         0.443   0.348   0.225   0.616   0.511   0.317   0.417   0.265   0.026
231   Q         1.175   1.200   1.266   1.210   1.245   1.344   1.257   1.291   1.388
232   A        -0.246  -0.443  -0.503  -0.120  -0.408  -0.496  -0.284  -0.548  -0.635
233   W         1.175   1.200   1.266   1.340   1.372   1.466   1.257   1.291   1.388
234   C        -0.246  -0.443  -0.503   0.042  -0.241  -0.375  -0.284  -0.548  -0.635
235   L         0.107   0.021   0.103  -0.176  -0.310  -0.182  -0.144  -0.307  -0.198
236   E        -0.530  -0.556  -0.560  -0.597  -0.671  -0.672  -0.704  -0.754  -0.717
237   S        -1.236  -1.243  -1.079  -1.282  -1.274  -1.026  -1.265  -1.239  -1.028
238   I        -0.246  -0.443  -0.503  -0.072  -0.371  -0.526  -0.284  -0.548  -0.635
239   P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
240   S        -0.750  -0.718  -0.599  -0.977  -0.956  -0.755  -0.984  -0.934  -0.764
241   E         0.443   0.558   0.244   0.402   0.541   0.122   0.417   0.588   0.061
242   V        -0.043  -0.034   0.084  -0.287  -0.293  -0.094  -0.424  -0.411  -0.234
243   S        -1.943  -1.919  -1.774  -1.777  -1.724  -1.538  -1.545  -1.501  -1.306
244   Q        -1.590  -1.533  -1.450  -1.458  -1.367  -1.234  -1.405  -1.332  -1.185
245   E         1.175   1.200   1.266   1.052   1.081   1.197   1.257   1.291   1.388
246   L        -1.103  -0.997  -1.039  -1.171  -1.031  -1.015  -1.124  -1.009  -0.989
247   K        -1.103  -1.065  -1.041  -1.090  -1.027  -0.973  -1.124  -1.061  -0.989
248   S        -1.103  -1.142  -1.063  -1.056  -1.108  -0.980  -1.124  -1.147  -1.013
249   F        -0.530  -0.584  -0.548  -0.456  -0.540  -0.538  -0.704  -0.751  -0.699
250   D        -1.456  -1.420  -1.427  -1.345  -1.306  -1.348  -1.265  -1.212  -1.165
251   K        -0.246  -0.072  -0.458  -0.220   0.026  -0.545  -0.284  -0.043  -0.573
252   Y         1.175   1.200   1.266   1.210   1.253   1.344   1.257   1.291   1.388
253   K        -1.590  -1.471  -1.441  -1.518  -1.349  -1.298  -1.405  -1.281  -1.179
254   R        -1.943  -1.844  -1.764  -1.758  -1.598  -1.518  -1.545  -1.440  -1.299
255   E        -0.883  -0.693  -0.981  -0.897  -0.618  -1.072  -0.844  -0.604  -0.921
256   H        -1.456  -1.352  -1.422  -1.227  -1.077  -1.219  -1.265  -1.147  -1.160
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   N        -0.530  -0.483  -0.544  -0.494  -0.431  -0.504  -0.704  -0.652  -0.697
259   T        -1.103  -1.070  -1.065  -1.089  -1.049  -1.016  -1.124  -1.080  -1.014
260   D         0.107   0.077   0.109   0.105   0.052   0.058  -0.144  -0.203  -0.186
261   L         0.443   0.543   0.241   0.332   0.474   0.090   0.417   0.566   0.055
262   F         0.443   0.500   0.237   0.313   0.408   0.042   0.417   0.502   0.047
263   A        -1.103  -1.146  -1.064  -1.096  -1.186  -1.059  -1.124  -1.151  -1.014
264   D         1.175   1.200   1.266   1.171   1.210   1.308   1.257   1.291   1.388
265   Y         1.175   1.200   1.266   1.210   1.253   1.344   1.257   1.291   1.388
266   V         1.175   1.200   1.266   1.154   1.177   1.292   1.257   1.291   1.388
267   K        -1.103  -0.998  -1.039  -1.168  -1.016  -1.060  -1.124  -1.011  -0.989
268   L         0.443   0.348   0.225   0.304   0.196   0.003   0.417   0.265   0.026
269   E         1.175   1.200   1.266   1.052   1.081   1.197   1.257   1.291   1.388
270   S        -0.617  -0.555  -0.552  -0.775  -0.633  -0.638  -0.844  -0.752  -0.709
271   R        -1.943  -1.898  -1.778  -1.842  -1.778  -1.635  -1.545  -1.485  -1.308
272   E         0.107   0.021   0.103  -0.121  -0.289  -0.164  -0.144  -0.307  -0.198
273   K        -0.883  -0.990  -1.027  -0.773  -0.912  -0.967  -0.844  -0.963  -0.972
274   S        -0.246  -0.112  -0.463  -0.253  -0.074  -0.584  -0.284  -0.097  -0.579
275   R         1.175   1.200   1.266   1.215   1.244   1.350   1.257   1.291   1.388
276   V        -0.530  -0.482  -0.544  -0.532  -0.479  -0.605  -0.704  -0.650  -0.697
277   V         1.175   1.200   1.266   1.154   1.177   1.292   1.257   1.291   1.388
278   V        -1.943  -1.921  -1.775  -1.714  -1.655  -1.473  -1.545  -1.502  -1.307
279   E         0.107   0.021   0.103  -0.070  -0.225  -0.088  -0.144  -0.307  -0.198
280   N         1.175   1.200   1.266   1.181   1.225   1.317   1.257   1.291   1.388
281   E        -0.246  -0.315  -0.482  -0.136  -0.237  -0.522  -0.284  -0.378  -0.606
282   S         0.443   0.348   0.225   0.495   0.379   0.192   0.417   0.265   0.026
283   F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
284   I        -0.043  -0.034   0.084  -0.312  -0.328  -0.149  -0.424  -0.411  -0.234
285   V         1.175   1.200   1.266   1.154   1.177   1.292   1.257   1.291   1.388
286   V         1.175   1.200   1.266   1.154   1.177   1.292   1.257   1.291   1.388
287   V         0.443   0.348   0.225   0.532   0.405   0.244   0.417   0.265   0.026
288   P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
289   Y         0.443   0.348   0.225   0.591   0.483   0.299   0.417   0.265   0.026
290   W         1.175   1.200   1.266   1.340   1.372   1.466   1.257   1.291   1.388
291   A         1.175   1.200   1.266   1.146   1.169   1.285   1.257   1.291   1.388
292   I        -0.617  -0.544  -0.555  -0.864  -0.721  -0.698  -0.844  -0.735  -0.711
293   W         1.175   1.200   1.266   1.340   1.372   1.466   1.257   1.291   1.388
294   P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
295   F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
296   E         1.175   1.200   1.266   1.052   1.081   1.197   1.257   1.291   1.388
297   T         0.443   0.348   0.225   0.529   0.394   0.203   0.417   0.265   0.026
298   L         0.107   0.076   0.113  -0.122  -0.152  -0.091  -0.144  -0.206  -0.180
299   V        -0.617  -0.657  -0.562  -0.864  -0.868  -0.711  -0.844  -0.861  -0.719
300   I        -0.246  -0.318  -0.481  -0.072  -0.176  -0.484  -0.284  -0.382  -0.604
301   S         0.107   0.110   0.114  -0.021  -0.026  -0.044  -0.144  -0.144  -0.178
302   K         1.175   1.200   1.266   1.080   1.127   1.223   1.257   1.291   1.388
303   K        -1.103  -1.022  -1.050  -1.172  -1.072  -1.073  -1.124  -1.032  -1.000
304   K        -0.530  -0.522  -0.551  -0.478  -0.477  -0.538  -0.704  -0.698  -0.705
305   L        -0.530  -0.559  -0.562  -0.739  -0.787  -0.735  -0.704  -0.757  -0.720
306   A        -1.590  -1.574  -1.451  -1.565  -1.530  -1.352  -1.405  -1.362  -1.186
307   S         0.443   0.348   0.225   0.479   0.353   0.157   0.417   0.265   0.026
308   I        -0.043  -0.020   0.086  -0.312  -0.269  -0.130  -0.424  -0.385  -0.230
309   S        -1.943  -1.858  -1.766  -1.870  -1.738  -1.611  -1.545  -1.450  -1.300
310   Q        -1.103  -1.096  -1.051  -1.178  -1.176  -1.086  -1.124  -1.097  -0.999
311   F         0.107   0.021   0.103  -0.020  -0.208  -0.114  -0.144  -0.307  -0.198
312   N        -0.530  -0.381  -0.524  -0.567  -0.342  -0.573  -0.704  -0.493  -0.667
313   Q        -1.590  -1.625  -1.459  -1.611  -1.657  -1.402  -1.405  -1.404  -1.192
314   M        -0.530  -0.556  -0.560  -0.656  -0.733  -0.680  -0.704  -0.754  -0.717
315   V        -1.103  -1.031  -1.050  -1.090  -1.015  -1.006  -1.124  -1.039  -1.000
316   K        -1.103  -1.123  -1.058  -1.128  -1.153  -1.035  -1.124  -1.132  -1.007
317   E        -1.590  -1.538  -1.450  -1.758  -1.669  -1.520  -1.405  -1.338  -1.186
318   D        -0.246  -0.443  -0.503  -0.084  -0.348  -0.454  -0.284  -0.548  -0.635
319   L         0.443   0.348   0.225   0.313   0.211   0.024   0.417   0.265   0.026
320   A         1.175   1.200   1.266   1.146   1.169   1.285   1.257   1.291   1.388
321   S        -0.883  -0.980  -1.026  -0.789  -0.954  -1.034  -0.844  -0.953  -0.970
322   I        -0.043  -0.034   0.084  -0.197  -0.207  -0.017  -0.424  -0.412  -0.235
323   L        -0.530  -0.629  -0.562  -0.714  -0.831  -0.714  -0.704  -0.822  -0.720
324   K        -0.883  -1.023  -1.035  -0.793  -0.990  -1.010  -0.844  -0.998  -0.980
325   Q        -2.296  -2.229  -2.053  -2.018  -1.956  -1.679  -1.685  -1.608  -1.394
326   L        -0.246  -0.443  -0.503  -0.310  -0.561  -0.650  -0.284  -0.548  -0.635
327   T         1.175   1.200   1.266   1.179   1.208   1.316   1.257   1.291   1.388
328   I        -1.103  -1.202  -1.071  -1.036  -1.179  -0.989  -1.124  -1.198  -1.020
329   K         0.107   0.085   0.110  -0.042  -0.076  -0.052  -0.144  -0.190  -0.185
330   Y         1.175   1.200   1.266   1.210   1.253   1.344   1.257   1.291   1.388
331   D         1.175   1.200   1.266   1.171   1.210   1.308   1.257   1.291   1.388
332   N         0.443   0.331   0.228   0.519   0.375   0.182   0.417   0.237   0.032
333   L         1.175   1.200   1.266   0.954   1.008   1.105   1.257   1.291   1.388
334   F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
335   E        -0.043  -0.026   0.084  -0.314  -0.295  -0.127  -0.424  -0.397  -0.234
336   T         1.175   1.200   1.266   1.179   1.208   1.316   1.257   1.291   1.388
337   S         0.443   0.348   0.225   0.485   0.365   0.170   0.417   0.265   0.026
338   F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
339   P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
340   Y         1.175   1.200   1.266   1.210   1.253   1.344   1.257   1.291   1.388
341   S         1.175   1.200   1.266   1.130   1.168   1.270   1.257   1.291   1.388
342   M         0.443   0.348   0.225   0.657   0.529   0.311   0.417   0.265   0.026
343   G         1.175   1.200   1.266   1.238   1.285   1.371   1.257   1.291   1.388
344   I         0.107   0.195   0.137   0.026   0.187   0.008  -0.144   0.008  -0.135
345   H         1.175   1.200   1.266   1.253   1.296   1.385   1.257   1.291   1.388
346   Q         1.175   1.200   1.266   1.210   1.245   1.344   1.257   1.291   1.388
347   A         0.443   0.331   0.228   0.492   0.329   0.170   0.417   0.237   0.032
348   P        -0.246  -0.318  -0.481  -0.147  -0.250  -0.499  -0.284  -0.382  -0.604
349   L        -0.246  -0.266  -0.475  -0.320  -0.341  -0.629  -0.284  -0.316  -0.595
350   N        -1.103  -0.942  -1.035  -1.084  -0.839  -0.979  -1.124  -0.934  -0.983
351   A        -1.236  -1.244  -1.080  -1.167  -1.171  -0.932  -1.265  -1.241  -1.029
352   T         0.371   0.480   0.211   0.432   0.579   0.173   0.304   0.472   0.002
353   G        -1.609  -1.457  -1.452  -1.545  -1.327  -1.303  -1.412  -1.242  -1.187
354   D        -0.246  -0.167  -0.475  -0.212  -0.108  -0.528  -0.284  -0.170  -0.596
355   E        -0.246  -0.266  -0.475  -0.216  -0.255  -0.535  -0.284  -0.316  -0.595
356   L        -1.943  -1.898  -1.778  -1.906  -1.802  -1.629  -1.545  -1.485  -1.308
357   S        -1.456  -1.428  -1.428  -1.436  -1.403  -1.403  -1.265  -1.220  -1.165
358   N        -1.456  -1.503  -1.443  -1.216  -1.295  -1.201  -1.265  -1.295  -1.178
359   S        -0.246  -0.318  -0.481  -0.176  -0.292  -0.554  -0.284  -0.382  -0.604
360   W         0.443   0.331   0.228   0.705   0.557   0.385   0.417   0.237   0.032
361   F         0.443   0.331   0.228   0.524   0.364   0.159   0.417   0.237   0.032
362   H         0.443   0.331   0.228   0.613   0.471   0.296   0.417   0.237   0.032
363   M         0.443   0.331   0.228   0.630   0.468   0.254   0.417   0.237   0.032
364   H         0.443   0.331   0.228   0.571   0.418   0.201   0.417   0.237   0.032
365   F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
366   Y         1.175   1.200   1.266   1.210   1.253   1.344   1.257   1.291   1.388
367   P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
368   P         1.175   1.200   1.266   1.132   1.165   1.272   1.257   1.291   1.388
369   L         1.175   1.200   1.266   0.954   1.008   1.105   1.257   1.291   1.388
370   L         1.175   1.200   1.266   0.954   1.008   1.105   1.257   1.291   1.388
371   R         1.175   1.200   1.266   1.215   1.244   1.350   1.257   1.291   1.388
372   S         1.175   1.200   1.266   1.130   1.168   1.270   1.257   1.291   1.388
373   A         1.175   1.200   1.266   1.146   1.169   1.285   1.257   1.291   1.388
374   T         0.443   0.331   0.228   0.525   0.367   0.199   0.417   0.237   0.032
375   V         1.175   1.200   1.266   1.154   1.177   1.292   1.257   1.291   1.388
376   R        -0.043  -0.026   0.084  -0.296  -0.265  -0.089  -0.424  -0.397  -0.234
377   K         1.175   1.200   1.266   1.080   1.127   1.223   1.257   1.291   1.388
378   F         1.175   1.200   1.266   1.206   1.241   1.341   1.257   1.291   1.388
379   L        -0.617  -0.657  -0.562  -0.749  -0.797  -0.651  -0.844  -0.861  -0.719
380   V         1.175   1.200   1.266   1.154   1.177   1.292   1.257   1.291   1.388
381   G         1.175   1.200   1.266   1.238   1.285   1.371   1.257   1.291   1.388
382   F         0.443   0.348   0.225   0.565   0.444   0.247   0.417   0.265   0.026
383   E         1.175   1.200   1.266   1.052   1.081   1.197   1.257   1.291   1.388
384   L        -0.043  -0.026   0.084  -0.262  -0.243  -0.097  -0.424  -0.397  -0.234
385   L         0.443   0.348   0.225   0.332   0.236   0.067   0.417   0.265   0.026
386   G         0.443   0.348   0.225   0.587   0.469   0.252   0.417   0.265   0.026
387   E        -0.246  -0.318  -0.481  -0.189  -0.287  -0.493  -0.284  -0.382  -0.604
388   P         0.443   0.543   0.241   0.479   0.606   0.181   0.417   0.566   0.055
389   Q         1.175   1.200   1.266   1.210   1.245   1.344   1.257   1.291   1.388
390   R         1.175   1.200   1.266   1.215   1.244   1.350   1.257   1.291   1.388
391   D         1.175   1.200   1.266   1.171   1.210   1.308   1.257   1.291   1.388
392   L         0.107   0.021   0.103  -0.146  -0.264  -0.137  -0.144  -0.307  -0.198
393   T         1.175   1.200   1.266   1.179   1.208   1.316   1.257   1.291   1.388
394   S        -0.530  -0.629  -0.562  -0.609  -0.770  -0.665  -0.704  -0.822  -0.720
395   E         1.175   1.200   1.266   1.052   1.081   1.197   1.257   1.291   1.388
396   Q         0.443   0.331   0.228   0.574   0.431   0.266   0.417   0.237   0.032
397   A         1.175   1.200   1.266   1.146   1.169   1.285   1.257   1.291   1.388
398   A         1.175   1.200   1.266   1.146   1.169   1.285   1.257   1.291   1.388
399   E        -1.456  -1.428  -1.428  -1.376  -1.353  -1.373  -1.265  -1.220  -1.165
400   K         0.443   0.500   0.237   0.553   0.626   0.228   0.417   0.502   0.047
401   L         1.175   1.200   1.266   0.954   1.008   1.105   1.257   1.291   1.388
402   R        -1.103  -1.148  -1.063  -1.033  -1.095  -0.980  -1.124  -1.153  -1.013
403   N        -1.103  -0.984  -1.034  -1.145  -0.937  -1.026  -1.124  -0.963  -0.982
404   L         0.443   0.348   0.225   0.334   0.239   0.070   0.417   0.265   0.026
405   D        -1.041  -1.083  -1.058  -0.940  -1.003  -0.985  -1.031  -1.071  -1.005
406   G         1.175   1.200   1.266   1.233   1.268   1.366   1.257   1.291   1.388
407   Q        -0.785  -0.732  -0.604  -0.994  -0.925  -0.720  -1.031  -0.948  -0.771
408   I        -1.197  -1.219  -1.078  -1.315  -1.365  -1.134  -1.222  -1.219  -1.026
409   H         0.371   0.216   0.184   0.509   0.282   0.210   0.304   0.043  -0.048
410   Y         0.371   0.216   0.184   0.477   0.253   0.184   0.304   0.043  -0.048
411   L        -0.629  -0.577  -0.569  -0.914  -0.842  -0.767  -0.840  -0.778  -0.729
412   Q        -1.197  -1.149  -1.070  -1.235  -1.156  -1.038  -1.222  -1.147  -1.019
413   R        -0.629  -0.615  -0.570  -0.901  -0.893  -0.803  -0.840  -0.818  -0.731
414   L        -1.041  -1.036  -1.052  -1.140  -1.130  -1.116  -1.031  -1.021  -0.998
415   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
416   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
417   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
418   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
419   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
420   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
421   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P08431
Output conservation file - output/P08431
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
