1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     M         1.562   1.600   1.680   1.756   1.811   1.931   1.716   1.773   1.904
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     D         0.274   0.329   0.037   0.435   0.518   0.071   0.260   0.341  -0.102
6     S        -1.169  -1.191  -1.047  -1.249  -1.269  -1.062  -1.083  -1.083  -0.910
7     K        -0.014  -0.138  -0.123  -0.313  -0.495  -0.463  -0.187  -0.356  -0.351
8     E         0.404   0.438   0.510   0.177   0.226   0.330   0.036   0.088   0.171
9     V        -0.144  -0.200  -0.129  -0.184  -0.240  -0.146  -0.411  -0.458  -0.360
10    L        -1.169  -1.172  -1.056  -1.354  -1.364  -1.179  -1.083  -1.070  -0.917
11    V        -1.054  -1.077  -1.034  -1.177  -1.225  -1.193  -0.971  -0.977  -0.895
12    H        -1.054  -1.065  -1.005  -0.905  -0.935  -0.842  -0.971  -0.967  -0.867
13    V        -0.318  -0.471  -0.576  -0.122  -0.341  -0.518  -0.299  -0.490  -0.615
14    K        -0.751  -0.681  -0.649  -1.128  -1.043  -0.951  -0.859  -0.778  -0.707
15    N        -1.054  -1.011  -1.022  -1.010  -0.974  -0.963  -0.971  -0.929  -0.886
16    L         1.562   1.600   1.680   1.520   1.575   1.701   1.716   1.773   1.904
17    E         0.274   0.227   0.016   0.347   0.267  -0.027   0.260   0.183  -0.133
18    K         1.562   1.600   1.680   1.261   1.318   1.447   1.716   1.773   1.904
19    N        -0.259  -0.156  -0.152  -0.492  -0.330  -0.352  -0.523  -0.371  -0.386
20    K        -1.054  -1.056  -1.038  -1.225  -1.205  -1.143  -0.971  -0.966  -0.901
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    S        -1.256  -1.210  -1.089  -1.449  -1.416  -1.207  -1.151  -1.096  -0.944
24    N        -0.111  -0.151  -0.117  -0.144  -0.163  -0.135  -0.331  -0.367  -0.336
25    D        -0.866  -0.969  -1.000  -0.545  -0.673  -0.737  -0.747  -0.855  -0.859
26    A        -0.636  -0.560  -0.589  -0.752  -0.670  -0.658  -0.747  -0.663  -0.648
27    A        -0.562  -0.461  -0.594  -0.580  -0.434  -0.650  -0.635  -0.509  -0.646
28    V         0.404   0.446   0.514   0.260   0.327   0.417   0.036   0.104   0.178
29    L        -0.562  -0.581  -0.622  -0.411  -0.446  -0.445  -0.635  -0.672  -0.679
30    E        -0.562  -0.559  -0.587  -0.809  -0.785  -0.816  -0.635  -0.612  -0.632
31    I         0.404   0.421   0.504   0.274   0.296   0.398   0.036   0.054   0.158
32    L         0.903   0.868   0.723   0.982   0.953   0.775   0.932   0.873   0.588
33    H        -1.472  -1.485  -1.375  -1.196  -1.224  -1.048  -1.195  -1.189  -1.042
34    V        -1.054  -1.119  -1.031  -0.934  -1.041  -0.931  -0.971  -1.019  -0.894
35    L         1.562   1.600   1.680   1.520   1.575   1.701   1.716   1.773   1.904
36    D        -1.169  -1.112  -1.058  -1.252  -1.196  -1.080  -1.083  -1.017  -0.918
37    K        -0.562  -0.642  -0.623  -0.759  -0.849  -0.811  -0.635  -0.707  -0.674
38    E        -0.259  -0.229  -0.159  -0.371  -0.337  -0.233  -0.523  -0.484  -0.398
39    F        -0.318  -0.355  -0.522  -0.105  -0.176  -0.402  -0.299  -0.350  -0.549
40    V        -0.333  -0.296  -0.193  -0.744  -0.698  -0.543  -0.635  -0.583  -0.446
41    P         0.274   0.274   0.035   0.544   0.545   0.189   0.260   0.260  -0.104
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    T         0.274   0.389   0.055   0.392   0.551   0.070   0.260   0.427  -0.074
44    E         1.562   1.600   1.680   1.485   1.533   1.666   1.716   1.773   1.904
45    K         0.578   0.496   0.533   0.216   0.070   0.117   0.372   0.202   0.218
46    L         0.903   0.787   0.710   0.973   0.838   0.736   0.932   0.738   0.565
47    L         1.562   1.600   1.680   1.520   1.575   1.701   1.716   1.773   1.904
48    R         0.903   0.868   0.723   0.970   0.918   0.678   0.932   0.873   0.588
49    E         0.903   0.787   0.710   0.903   0.745   0.626   0.932   0.738   0.565
50    T         1.562   1.600   1.680   1.539   1.595   1.719   1.716   1.773   1.904
51    K         0.903   0.868   0.723   0.696   0.662   0.471   0.932   0.873   0.588
52    V        -0.014  -0.138  -0.123  -0.034  -0.231  -0.236  -0.187  -0.356  -0.351
53    G         1.562   1.600   1.680   1.654   1.709   1.832   1.716   1.773   1.904
54    V         0.274   0.233   0.013   0.432   0.384   0.065   0.260   0.203  -0.138
55    E        -0.751  -0.793  -0.667  -0.903  -0.965  -0.768  -0.859  -0.885  -0.728
56    V         1.562   1.600   1.680   1.551   1.604   1.731   1.716   1.773   1.904
57    N         0.578   0.496   0.533   0.542   0.414   0.449   0.372   0.202   0.218
58    K         0.903   0.972   0.739   0.714   0.808   0.533   0.932   1.039   0.619
59    F         0.404   0.387   0.489   0.378   0.315   0.447   0.036  -0.014   0.126
60    K         0.404   0.471   0.539   0.087   0.213   0.290   0.036   0.153   0.230
61    K        -1.054  -1.081  -1.042  -1.275  -1.324  -1.204  -0.971  -0.987  -0.904
62    S        -0.259  -0.271  -0.200  -0.363  -0.378  -0.263  -0.523  -0.542  -0.454
63    T        -1.054  -0.983  -1.012  -0.988  -0.877  -0.917  -0.971  -0.904  -0.877
64    N         0.274   0.347   0.041   0.399   0.512   0.061   0.260   0.367  -0.096
65    V        -1.472  -1.507  -1.362  -1.459  -1.573  -1.336  -1.195  -1.204  -1.033
66    E        -0.562  -0.628  -0.621  -0.613  -0.729  -0.729  -0.635  -0.711  -0.678
67    I         0.578   0.604   0.562   0.605   0.647   0.535   0.372   0.409   0.275
68    S        -0.866  -0.926  -0.974  -0.745  -0.847  -0.915  -0.747  -0.811  -0.833
69    K        -1.358  -1.388  -1.371  -1.420  -1.460  -1.397  -1.083  -1.102  -1.038
70    L         0.274   0.108  -0.017   0.431   0.224   0.049   0.260   0.020  -0.183
71    V         0.578   0.496   0.533   0.498   0.333   0.365   0.372   0.202   0.218
72    K         0.274   0.108  -0.017   0.118  -0.107  -0.296   0.260   0.020  -0.183
73    K        -0.014  -0.033  -0.105  -0.309  -0.372  -0.433  -0.187  -0.249  -0.326
74    M         0.578   0.496   0.533   0.746   0.601   0.623   0.372   0.202   0.218
75    I         0.578   0.496   0.533   0.605   0.457   0.479   0.372   0.202   0.218
76    S        -1.472  -1.447  -1.372  -1.538  -1.524  -1.396  -1.195  -1.160  -1.040
77    S        -0.751  -0.702  -0.661  -1.067  -1.037  -0.959  -0.859  -0.805  -0.721
78    W         1.562   1.600   1.680   1.818   1.875   1.992   1.716   1.773   1.904
79    K         0.404   0.421   0.504  -0.028  -0.007   0.130   0.036   0.054   0.158
80    D        -0.318  -0.413  -0.549  -0.170  -0.339  -0.600  -0.299  -0.423  -0.583
81    A        -0.866  -0.949  -0.997  -0.729  -0.872  -0.940  -0.747  -0.835  -0.857
82    I         0.578   0.662   0.617   0.550   0.678   0.595   0.372   0.516   0.385
83    N        -1.472  -1.506  -1.388  -1.338  -1.411  -1.260  -1.195  -1.204  -1.052
84    K        -0.636  -0.553  -0.606  -0.925  -0.820  -0.838  -0.747  -0.655  -0.665
85    N        -1.358  -1.404  -1.353  -1.086  -1.173  -1.056  -1.083  -1.116  -1.023
86    K         0.903   0.868   0.723   0.696   0.662   0.471   0.932   0.873   0.588
87    R        -1.472  -1.475  -1.371  -1.510  -1.497  -1.328  -1.195  -1.182  -1.040
88    S        -1.472  -1.431  -1.360  -1.571  -1.498  -1.416  -1.195  -1.147  -1.031
89    R         0.274   0.328   0.035   0.122   0.196  -0.206   0.260   0.339  -0.104
90    Q        -1.054  -1.036  -1.025  -1.227  -1.196  -1.148  -0.971  -0.934  -0.887
91    A        -0.102   0.035  -0.096  -0.418  -0.212  -0.421  -0.291  -0.087  -0.302
92    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
93    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
94    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
95    H        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
96    Q        -1.171  -1.110  -1.047  -1.222  -1.143  -1.044  -1.071  -0.998  -0.905
97    D        -1.576  -1.551  -1.403  -1.404  -1.389  -1.163  -1.270  -1.234  -1.062
98    H        -1.021  -1.042  -1.028  -0.842  -0.891  -0.855  -0.917  -0.932  -0.887
99    A         0.168   0.169   0.000   0.365   0.368   0.085   0.107   0.109  -0.157
100   P        -1.499  -1.473  -1.370  -1.545  -1.528  -1.372  -1.209  -1.175  -1.038
101   G        -0.674  -0.576  -0.608  -0.803  -0.659  -0.729  -0.770  -0.643  -0.662
102   N        -1.021  -1.042  -1.028  -0.987  -1.035  -1.051  -0.917  -0.932  -0.887
103   A        -0.458  -0.388  -0.565  -0.251  -0.141  -0.473  -0.478  -0.381  -0.603
104   E        -0.866  -0.880  -0.962  -0.847  -0.894  -1.054  -0.747  -0.761  -0.821
105   D        -1.472  -1.467  -1.360  -1.539  -1.512  -1.344  -1.195  -1.176  -1.032
106   K        -1.776  -1.703  -1.632  -1.598  -1.451  -1.404  -1.307  -1.235  -1.123
107   T        -0.144  -0.076  -0.100  -0.375  -0.284  -0.288  -0.411  -0.315  -0.327
108   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
114   N        -0.771  -0.783  -0.687  -0.747  -0.761  -0.627  -0.864  -0.874  -0.746
115   G        -0.102  -0.195  -0.165  -0.016  -0.181  -0.167  -0.291  -0.430  -0.404
116   V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
117   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   P        -0.209  -0.195  -0.138  -0.308  -0.282  -0.193  -0.474  -0.448  -0.372
120   A        -1.152  -1.147  -1.054  -1.161  -1.145  -1.007  -1.063  -1.046  -0.914
121   S        -1.472  -1.409  -1.356  -1.507  -1.402  -1.355  -1.195  -1.129  -1.029
122   S        -0.014   0.019  -0.098  -0.053  -0.018  -0.166  -0.187  -0.163  -0.317
123   Q        -1.472  -1.455  -1.363  -1.331  -1.312  -1.220  -1.195  -1.167  -1.033
124   S        -1.472  -1.407  -1.352  -1.308  -1.242  -1.142  -1.195  -1.129  -1.025
125   D        -1.472  -1.438  -1.364  -1.497  -1.421  -1.340  -1.195  -1.152  -1.034
126   A        -0.866  -0.762  -0.949  -0.747  -0.634  -0.891  -0.747  -0.625  -0.807
127   M        -1.776  -1.780  -1.661  -1.425  -1.394  -1.227  -1.307  -1.294  -1.143
128   K        -1.054  -1.104  -1.047  -1.289  -1.340  -1.231  -0.971  -1.004  -0.908
129   Q        -0.327  -0.332  -0.209  -0.574  -0.606  -0.422  -0.624  -0.629  -0.468
130   D        -0.362  -0.320  -0.203  -0.506  -0.425  -0.269  -0.673  -0.613  -0.459
131   K        -0.259  -0.241  -0.171  -0.586  -0.532  -0.416  -0.523  -0.502  -0.415
132   Y        -1.472  -1.402  -1.364  -1.224  -1.122  -1.095  -1.195  -1.124  -1.034
133   V        -1.358  -1.388  -1.371  -1.065  -1.118  -1.084  -1.083  -1.102  -1.038
134   S        -0.866  -0.865  -0.983  -0.642  -0.651  -0.772  -0.747  -0.745  -0.842
135   T        -0.562  -0.583  -0.582  -0.740  -0.748  -0.785  -0.635  -0.645  -0.631
136   K        -0.562  -0.582  -0.607  -0.577  -0.596  -0.687  -0.635  -0.644  -0.656
137   P        -0.562  -0.623  -0.619  -0.376  -0.500  -0.499  -0.635  -0.707  -0.675
138   R         1.562   1.600   1.680   1.577   1.624   1.757   1.716   1.773   1.904
139   N        -0.014  -0.138  -0.123   0.019  -0.131  -0.126  -0.187  -0.356  -0.351
140   S        -1.054  -0.994  -1.030  -0.803  -0.711  -0.798  -0.971  -0.914  -0.893
141   K         0.903   0.928   0.727   0.680   0.720   0.443   0.932   0.970   0.595
142   N        -0.636  -0.653  -0.636  -0.767  -0.778  -0.799  -0.747  -0.748  -0.694
143   D         1.562   1.600   1.680   1.590   1.650   1.769   1.716   1.773   1.904
144   G         0.274   0.108  -0.017   0.478   0.232  -0.011   0.260   0.020  -0.183
145   V         0.903   1.002   0.739   0.996   1.121   0.791   0.932   1.085   0.618
146   D        -0.636  -0.597  -0.618  -0.728  -0.652  -0.725  -0.747  -0.696  -0.677
147   T        -0.318  -0.421  -0.547  -0.095  -0.235  -0.412  -0.299  -0.432  -0.581
148   A        -1.358  -1.228  -1.303  -1.150  -0.950  -1.089  -1.083  -0.945  -0.981
149   I        -0.751  -0.783  -0.660  -0.748  -0.778  -0.617  -0.859  -0.873  -0.720
150   Y        -0.014  -0.033  -0.105   0.208   0.132   0.058  -0.187  -0.249  -0.326
151   H        -1.472  -1.380  -1.353  -1.291  -1.173  -1.111  -1.195  -1.107  -1.027
152   H        -1.054  -1.082  -1.030  -0.920  -0.966  -0.870  -0.971  -0.990  -0.893
153   K        -0.318  -0.314  -0.536  -0.380  -0.365  -0.652  -0.299  -0.300  -0.566
154   L        -0.751  -0.720  -0.658  -0.786  -0.728  -0.639  -0.859  -0.813  -0.718
155   R         1.562   1.600   1.680   1.577   1.624   1.757   1.716   1.773   1.904
156   D         0.404   0.471   0.539   0.223   0.345   0.425   0.036   0.153   0.230
157   Q        -1.169  -1.119  -1.059  -1.044  -0.979  -0.861  -1.083  -1.021  -0.919
158   V        -1.169  -1.174  -1.062  -1.103  -1.085  -0.934  -1.083  -1.070  -0.921
159   L        -0.014   0.104  -0.035   0.067   0.257   0.030  -0.187  -0.007  -0.214
160   K        -1.169  -1.119  -1.059  -1.199  -1.089  -1.043  -1.083  -1.022  -0.918
161   A        -0.014  -0.110  -0.124  -0.086  -0.253  -0.267  -0.187  -0.331  -0.354
162   L         0.274   0.233   0.013   0.425   0.385   0.083   0.260   0.203  -0.138
163   Y         1.562   1.600   1.680   1.740   1.798   1.916   1.716   1.773   1.904
164   D        -0.333  -0.338  -0.209  -0.499  -0.504  -0.326  -0.635  -0.637  -0.467
165   V        -0.318  -0.339  -0.512  -0.199  -0.240  -0.486  -0.299  -0.330  -0.537
166   L         1.562   1.600   1.680   1.520   1.575   1.701   1.716   1.773   1.904
167   A         0.903   0.868   0.723   0.907   0.855   0.667   0.932   0.873   0.588
168   K        -0.751  -0.797  -0.677  -0.932  -0.946  -0.740  -0.859  -0.890  -0.738
169   E        -0.636  -0.694  -0.612  -0.641  -0.706  -0.569  -0.747  -0.791  -0.671
170   S        -0.144  -0.131  -0.129  -0.268  -0.251  -0.192  -0.411  -0.392  -0.366
171   E        -0.751  -0.720  -0.674  -0.846  -0.810  -0.721  -0.859  -0.828  -0.736
172   H        -0.751  -0.736  -0.674  -0.659  -0.669  -0.598  -0.859  -0.836  -0.735
173   P        -0.144  -0.101  -0.116  -0.199  -0.133  -0.105  -0.411  -0.339  -0.341
174   P        -0.318  -0.413  -0.549   0.017  -0.120  -0.339  -0.299  -0.423  -0.583
175   Q        -1.472  -1.449  -1.355  -1.583  -1.532  -1.388  -1.195  -1.159  -1.028
176   S        -1.169  -1.145  -1.057  -1.132  -1.116  -0.992  -1.083  -1.044  -0.917
177   I         0.578   0.522   0.537   0.605   0.505   0.487   0.372   0.253   0.226
178   L         0.274   0.108  -0.017   0.407   0.190  -0.000   0.260   0.020  -0.183
179   H        -1.358  -1.314  -1.328  -1.164  -1.164  -1.122  -1.083  -1.034  -1.003
180   T        -1.358  -1.388  -1.371  -1.143  -1.210  -1.185  -1.083  -1.102  -1.038
181   A        -0.014   0.105  -0.051  -0.118   0.055  -0.183  -0.187  -0.005  -0.244
182   K        -1.054  -1.028  -1.003  -1.093  -1.068  -0.973  -0.971  -0.931  -0.868
183   A        -0.636  -0.548  -0.608  -0.773  -0.668  -0.711  -0.747  -0.648  -0.666
184   I         0.903   0.787   0.710   1.068   0.928   0.800   0.932   0.738   0.565
185   E         0.903   0.868   0.723   0.923   0.882   0.689   0.932   0.873   0.588
186   S        -1.054  -0.963  -1.002  -1.074  -0.938  -1.014  -0.971  -0.873  -0.868
187   E         0.274   0.108  -0.017   0.369   0.136  -0.038   0.260   0.020  -0.183
188   M        -0.144  -0.200  -0.129  -0.127  -0.197  -0.095  -0.411  -0.458  -0.360
189   N        -1.472  -1.428  -1.356  -1.054  -0.989  -0.906  -1.195  -1.145  -1.029
190   K         0.274   0.274   0.035   0.115   0.117  -0.220   0.260   0.260  -0.104
191   V        -1.472  -1.443  -1.363  -1.366  -1.330  -1.197  -1.195  -1.155  -1.033
192   N        -1.054  -1.107  -1.041  -0.936  -0.989  -0.868  -0.971  -1.005  -0.901
193   N        -1.054  -1.089  -1.033  -0.961  -1.050  -0.976  -0.971  -0.988  -0.893
194   C        -1.171  -1.169  -1.057  -1.028  -1.012  -0.849  -1.071  -1.059  -0.915
195   D        -1.169  -1.112  -1.047  -1.329  -1.221  -1.136  -1.083  -1.020  -0.910
196   T        -1.054  -1.032  -1.005  -1.000  -0.968  -0.931  -0.971  -0.933  -0.867
197   N        -1.054  -0.963  -0.989  -1.017  -0.867  -0.947  -0.971  -0.879  -0.855
198   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   A        -1.472  -1.507  -1.387  -1.486  -1.502  -1.335  -1.195  -1.204  -1.051
200   A        -1.054  -0.944  -0.992  -1.052  -0.890  -0.960  -0.971  -0.847  -0.857
201   Y         1.562   1.600   1.680   1.740   1.798   1.916   1.716   1.773   1.904
202   K         0.578   0.662   0.617   0.457   0.592   0.469   0.372   0.516   0.385
203   A        -1.054  -1.077  -1.033  -0.971  -1.000  -0.945  -0.971  -0.977  -0.895
204   R         0.404   0.438   0.504  -0.028   0.019   0.130   0.036   0.087   0.157
205   Y        -0.751  -0.791  -0.676  -0.552  -0.583  -0.435  -0.859  -0.884  -0.737
206   R         1.562   1.600   1.680   1.577   1.624   1.757   1.716   1.773   1.904
207   I        -0.751  -0.699  -0.653  -0.842  -0.776  -0.693  -0.859  -0.800  -0.713
208   I        -0.333  -0.266  -0.175  -0.382  -0.296  -0.157  -0.635  -0.542  -0.420
209   Y        -0.014  -0.050  -0.072   0.203   0.193   0.126  -0.187  -0.216  -0.269
210   S        -0.636  -0.694  -0.643  -0.556  -0.620  -0.530  -0.747  -0.791  -0.702
211   N         0.903   0.787   0.710   0.955   0.813   0.675   0.932   0.738   0.565
212   V        -0.014   0.088  -0.066  -0.004   0.150  -0.076  -0.187  -0.033  -0.261
213   I        -0.333  -0.266  -0.175  -0.635  -0.569  -0.428  -0.635  -0.542  -0.420
214   S        -0.751  -0.791  -0.676  -0.861  -0.895  -0.727  -0.859  -0.884  -0.737
215   K         0.274   0.348   0.041   0.159   0.261  -0.128   0.260   0.367  -0.096
216   N        -0.144  -0.203  -0.131  -0.431  -0.470  -0.386  -0.411  -0.463  -0.367
217   N         1.562   1.600   1.680   1.537   1.600   1.717   1.716   1.773   1.904
218   P         0.903   0.787   0.710   1.100   0.948   0.817   0.932   0.738   0.565
219   D        -0.866  -0.956  -0.999  -0.693  -0.860  -0.975  -0.747  -0.842  -0.858
220   L         1.562   1.600   1.680   1.520   1.575   1.701   1.716   1.773   1.904
221   K        -0.144  -0.200  -0.129  -0.381  -0.423  -0.307  -0.411  -0.458  -0.360
222   H        -1.776  -1.763  -1.655  -1.376  -1.379  -1.255  -1.307  -1.283  -1.139
223   K        -0.562  -0.559  -0.587  -0.643  -0.617  -0.700  -0.635  -0.612  -0.632
224   I        -0.144  -0.091  -0.128  -0.184  -0.133  -0.160  -0.411  -0.359  -0.366
225   A        -1.054  -1.077  -1.034  -0.957  -0.959  -0.890  -0.971  -0.977  -0.895
226   N        -0.636  -0.608  -0.619  -0.732  -0.688  -0.682  -0.747  -0.706  -0.675
227   G        -0.014   0.055  -0.087   0.033   0.138  -0.142  -0.187  -0.095  -0.299
228   D        -0.751  -0.657  -0.636  -0.949  -0.803  -0.762  -0.859  -0.743  -0.692
229   I        -0.014  -0.006  -0.089   0.062   0.058  -0.085  -0.187  -0.192  -0.306
230   T        -1.054  -1.049  -1.019  -1.111  -1.080  -1.068  -0.971  -0.961  -0.884
231   P        -0.014  -0.095  -0.095   0.085  -0.027  -0.075  -0.187  -0.286  -0.309
232   E        -0.866  -0.778  -0.946  -0.796  -0.660  -0.967  -0.747  -0.642  -0.805
233   F        -1.358  -1.186  -1.316  -0.977  -0.744  -0.911  -1.083  -0.903  -0.992
234   L         0.578   0.680   0.626   0.560   0.710   0.631   0.372   0.550   0.403
235   A        -1.054  -1.028  -1.014  -0.910  -0.868  -0.851  -0.971  -0.924  -0.875
236   T        -1.054  -1.057  -1.018  -1.139  -1.110  -1.062  -0.971  -0.957  -0.879
237   C        -0.866  -0.856  -0.980  -0.458  -0.459  -0.683  -0.747  -0.735  -0.839
238   D        -0.333  -0.333  -0.207  -0.537  -0.548  -0.373  -0.635  -0.632  -0.465
239   A        -0.318  -0.438  -0.550  -0.026  -0.201  -0.419  -0.299  -0.451  -0.584
240   K        -0.562  -0.547  -0.601  -0.772  -0.734  -0.790  -0.635  -0.594  -0.648
241   D         0.404   0.471   0.539   0.177   0.283   0.381   0.036   0.153   0.230
242   L         0.404   0.466   0.524   0.298   0.391   0.477   0.036   0.143   0.199
243   A         1.562   1.600   1.680   1.474   1.513   1.656   1.716   1.773   1.904
244   P         0.404   0.387   0.489   0.277   0.210   0.347   0.036  -0.014   0.126
245   A         0.274   0.328   0.035   0.351   0.420   0.010   0.260   0.339  -0.104
246   P        -1.472  -1.409  -1.365  -1.229  -1.159  -1.105  -1.195  -1.129  -1.034
247   L         0.274   0.108  -0.017   0.421   0.211   0.029   0.260   0.020  -0.183
248   K         0.578   0.496   0.533   0.249   0.113   0.171   0.372   0.202   0.218
249   Q         0.274   0.199   0.015   0.143   0.035  -0.195   0.260   0.146  -0.134
250   K        -0.144  -0.200  -0.129  -0.480  -0.531  -0.415  -0.411  -0.458  -0.360
251   I        -0.014  -0.033  -0.105   0.126   0.064  -0.006  -0.187  -0.249  -0.326
252   E         0.903   0.868   0.723   0.906   0.858   0.653   0.932   0.873   0.588
253   E         0.404   0.446   0.514   0.001   0.069   0.142   0.036   0.104   0.178
254   I        -0.144  -0.101  -0.116  -0.178  -0.104  -0.086  -0.411  -0.339  -0.341
255   A        -0.562  -0.421  -0.562  -0.544  -0.344  -0.579  -0.635  -0.449  -0.601
256   K         0.903   0.868   0.723   0.714   0.685   0.510   0.932   0.873   0.588
257   Q         0.578   0.496   0.533   0.639   0.474   0.492   0.372   0.202   0.218
258   N         1.562   1.600   1.680   1.537   1.600   1.717   1.716   1.773   1.904
259   L         0.903   0.787   0.710   0.982   0.852   0.757   0.932   0.738   0.565
260   Y         0.274   0.199   0.015   0.610   0.490   0.207   0.260   0.146  -0.134
261   N        -1.054  -1.124  -1.056  -0.992  -1.099  -1.012  -0.971  -1.018  -0.915
262   A         1.562   1.600   1.680   1.474   1.513   1.656   1.716   1.773   1.904
263   Q         0.903   0.928   0.727   1.128   1.166   0.888   0.932   0.970   0.595
264   G         0.903   0.787   0.710   1.086   0.940   0.817   0.932   0.738   0.565
265   A         0.903   0.787   0.710   0.926   0.775   0.689   0.932   0.738   0.565
266   T         0.274   0.108  -0.017   0.399   0.184  -0.039   0.260   0.020  -0.183
267   I        -1.054  -1.107  -1.041  -0.960  -1.042  -0.929  -0.971  -1.005  -0.901
268   E        -0.259  -0.214  -0.165  -0.495  -0.409  -0.355  -0.523  -0.460  -0.406
269   R         0.578   0.496   0.533   0.457   0.269   0.275   0.372   0.202   0.218
270   S         0.348   0.377   0.488  -0.023   0.006   0.189  -0.076  -0.035   0.124
271   V         0.903   0.787   0.710   0.996   0.856   0.747   0.932   0.738   0.565
272   T         0.903   0.787   0.710   0.957   0.808   0.677   0.932   0.738   0.565
273   D         1.562   1.600   1.680   1.590   1.650   1.769   1.716   1.773   1.904
274   R         0.274   0.108  -0.017   0.432   0.190  -0.015   0.260   0.020  -0.183
275   F         0.903   0.787   0.710   1.181   1.037   0.901   0.932   0.738   0.565
276   T         0.274   0.200   0.017   0.388   0.268  -0.004   0.260   0.147  -0.132
277   C         1.562   1.600   1.680   1.757   1.813   1.933   1.716   1.773   1.904
278   G         1.562   1.600   1.680   1.654   1.709   1.832   1.716   1.773   1.904
279   K         1.562   1.600   1.680   1.261   1.318   1.447   1.716   1.773   1.904
280   C         1.562   1.600   1.680   1.757   1.813   1.933   1.716   1.773   1.904
281   K         0.903   0.787   0.710   0.708   0.575   0.478   0.932   0.738   0.565
282   E        -0.259  -0.147  -0.120  -0.185  -0.008   0.009  -0.523  -0.358  -0.338
283   K         0.578   0.541   0.542   0.249   0.188   0.185   0.372   0.291   0.236
284   K         1.562   1.600   1.680   1.261   1.318   1.447   1.716   1.773   1.904
285   V         1.562   1.600   1.680   1.551   1.604   1.731   1.716   1.773   1.904
286   S         1.562   1.600   1.680   1.453   1.507   1.635   1.716   1.773   1.904
287   Y         1.562   1.600   1.680   1.740   1.798   1.916   1.716   1.773   1.904
288   Y         0.903   0.787   0.710   1.158   1.009   0.868   0.932   0.738   0.565
289   Q         1.562   1.600   1.680   1.692   1.746   1.869   1.716   1.773   1.904
290   L        -0.144  -0.200  -0.129  -0.113  -0.178  -0.085  -0.411  -0.458  -0.360
291   Q         1.562   1.600   1.680   1.692   1.746   1.869   1.716   1.773   1.904
292   T         1.562   1.600   1.680   1.539   1.595   1.719   1.716   1.773   1.904
293   R         1.562   1.600   1.680   1.577   1.624   1.757   1.716   1.773   1.904
294   S         1.562   1.600   1.680   1.453   1.507   1.635   1.716   1.773   1.904
295   A         1.562   1.600   1.680   1.474   1.513   1.656   1.716   1.773   1.904
296   D         1.562   1.600   1.680   1.590   1.650   1.769   1.716   1.773   1.904
297   E         1.562   1.600   1.680   1.485   1.533   1.666   1.716   1.773   1.904
298   P         1.562   1.600   1.680   1.678   1.735   1.856   1.716   1.773   1.904
299   L         0.578   0.496   0.533   0.560   0.437   0.491   0.372   0.202   0.218
300   T         1.562   1.600   1.680   1.539   1.595   1.719   1.716   1.773   1.904
301   T         1.562   1.600   1.680   1.539   1.595   1.719   1.716   1.773   1.904
302   F         1.562   1.600   1.680   1.754   1.813   1.929   1.716   1.773   1.904
303   C         1.562   1.600   1.680   1.757   1.813   1.933   1.716   1.773   1.904
304   T         0.578   0.496   0.533   0.489   0.333   0.360   0.372   0.202   0.218
305   C         1.562   1.600   1.680   1.757   1.813   1.933   1.716   1.773   1.904
306   E         0.578   0.496   0.533   0.455   0.302   0.343   0.372   0.202   0.218
307   A        -0.259  -0.266  -0.175  -0.422  -0.442  -0.321  -0.523  -0.539  -0.421
308   C         1.562   1.600   1.680   1.757   1.813   1.933   1.716   1.773   1.904
309   G         1.562   1.600   1.680   1.654   1.709   1.832   1.716   1.773   1.904
310   N         0.903   0.928   0.727   0.967   1.016   0.729   0.932   0.970   0.595
311   R         1.562   1.600   1.680   1.577   1.624   1.757   1.716   1.773   1.904
312   W         1.562   1.600   1.680   1.818   1.875   1.992   1.716   1.773   1.904
313   K         1.562   1.600   1.680   1.261   1.318   1.447   1.716   1.773   1.904
314   F         1.562   1.600   1.680   1.754   1.813   1.929   1.716   1.773   1.904
315   S         1.562   1.600   1.680   1.453   1.507   1.635   1.716   1.773   1.904
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P07273
Output conservation file - output/P07273
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
