1     M         0.997   1.034   1.082   1.168   1.217   1.278   1.049   1.099   1.169
2     F        -0.425  -0.542  -0.753  -0.160  -0.342  -0.705  -0.417  -0.568  -0.846
3     S        -1.348  -1.453  -1.309  -1.274  -1.436  -1.265  -1.319  -1.380  -1.190
4     N        -1.616  -1.398  -1.322  -1.608  -1.297  -1.172  -1.602  -1.343  -1.203
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    W        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
29    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
30    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
31    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
32    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
33    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
34    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
35    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
36    Q        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
37    R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
38    T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
39    L        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
40    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
41    K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
42    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
43    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
44    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
45    S        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
46    F        -2.466  -2.279  -2.045  -2.376  -2.108  -1.800  -1.958  -1.758  -1.481
47    Y        -2.018  -1.941  -1.711  -1.995  -1.922  -1.552  -1.770  -1.639  -1.364
48    S        -1.891  -1.798  -1.698  -1.845  -1.695  -1.608  -1.657  -1.521  -1.353
49    T        -0.743  -0.756  -0.791  -0.831  -0.895  -0.997  -0.868  -0.883  -0.899
50    A        -2.226  -2.182  -2.033  -2.043  -1.947  -1.656  -1.770  -1.695  -1.474
51    T        -2.018  -1.827  -1.700  -2.007  -1.745  -1.610  -1.770  -1.558  -1.356
52    G        -2.466  -2.281  -2.045  -2.226  -1.964  -1.670  -1.958  -1.758  -1.481
53    A        -2.020  -1.897  -1.715  -1.908  -1.738  -1.548  -1.757  -1.606  -1.366
54    A        -0.233  -0.116  -0.100  -0.592  -0.408  -0.338  -0.555  -0.362  -0.372
55    S        -2.020  -1.852  -1.706  -2.083  -1.833  -1.589  -1.757  -1.566  -1.359
56    K        -0.680  -0.600  -0.759  -0.659  -0.579  -0.865  -0.755  -0.651  -0.854
57    S        -1.578  -1.460  -1.313  -1.721  -1.546  -1.367  -1.549  -1.394  -1.193
58    G        -2.381  -2.269  -2.042  -2.131  -1.962  -1.657  -1.897  -1.753  -1.479
59    K        -1.348  -1.132  -1.282  -1.343  -1.083  -1.240  -1.319  -1.090  -1.165
60    L        -1.348  -1.114  -1.282  -1.323  -1.071  -1.180  -1.319  -1.081  -1.165
61    T        -1.556  -1.536  -1.321  -1.579  -1.555  -1.248  -1.544  -1.469  -1.202
62    Q        -0.743  -0.876  -0.802  -0.586  -0.836  -0.779  -0.868  -1.023  -0.912
63    K        -1.348  -1.269  -1.308  -1.270  -1.195  -1.260  -1.319  -1.241  -1.190
64    L        -1.556  -1.348  -1.313  -1.641  -1.324  -1.301  -1.544  -1.313  -1.195
65    V        -1.556  -1.396  -1.321  -1.708  -1.598  -1.413  -1.544  -1.355  -1.202
66    T        -1.891  -1.803  -1.701  -2.080  -1.981  -1.765  -1.657  -1.528  -1.356
67    A        -1.348  -1.443  -1.309  -1.448  -1.617  -1.393  -1.319  -1.385  -1.191
68    G        -0.886  -0.921  -0.798  -1.116  -1.167  -0.993  -1.093  -1.090  -0.907
69    V        -1.095  -1.018  -0.830  -1.481  -1.368  -1.058  -1.319  -1.198  -0.945
70    A        -1.556  -1.522  -1.316  -1.866  -1.765  -1.439  -1.544  -1.456  -1.197
71    A        -1.013  -1.005  -0.835  -1.303  -1.351  -1.109  -1.206  -1.180  -0.951
72    A        -1.891  -1.852  -1.704  -1.793  -1.766  -1.564  -1.657  -1.578  -1.358
73    G        -0.886  -0.953  -0.796  -1.240  -1.335  -1.072  -1.093  -1.124  -0.905
74    I        -1.891  -1.928  -1.716  -1.831  -1.942  -1.675  -1.657  -1.627  -1.368
75    T        -0.886  -0.824  -0.789  -1.075  -0.997  -0.964  -1.093  -0.990  -0.896
76    A        -1.348  -1.491  -1.316  -1.501  -1.630  -1.331  -1.319  -1.423  -1.197
77    S        -0.743  -0.824  -0.808  -0.680  -0.820  -0.769  -0.868  -0.991  -0.920
78    T        -1.095  -0.896  -0.805  -1.437  -1.180  -0.997  -1.319  -1.052  -0.915
79    L        -1.078  -1.056  -1.271  -0.876  -0.855  -1.078  -0.981  -0.952  -1.151
80    L        -0.282  -0.267  -0.119  -0.551  -0.516  -0.264  -0.642  -0.632  -0.406
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    Y         0.997   1.034   1.082   1.047   1.105   1.173   1.049   1.099   1.169
85    A        -1.471  -1.534  -1.326  -1.586  -1.646  -1.300  -1.455  -1.466  -1.206
86    D        -0.542  -0.830  -0.803  -0.435  -0.896  -0.912  -0.571  -0.949  -0.910
87    S        -0.425  -0.542  -0.753  -0.248  -0.403  -0.725  -0.417  -0.568  -0.846
88    L        -1.683  -1.533  -1.676  -1.510  -1.358  -1.499  -1.432  -1.268  -1.334
89    T        -0.542  -0.767  -0.803  -0.360  -0.676  -0.759  -0.571  -0.871  -0.910
90    A         0.997   1.034   1.082   0.659   0.715   0.836   1.049   1.099   1.169
91    E        -1.095  -0.899  -0.816  -1.263  -0.972  -0.848  -1.319  -1.057  -0.928
92    A         0.997   1.034   1.082   0.682   0.753   0.856   1.049   1.099   1.169
93    M         0.269   0.082  -0.034   0.534   0.271   0.032   0.260  -0.030  -0.253
94    T         0.997   1.034   1.082   1.007   1.067   1.138   1.049   1.099   1.169
95    A        -0.090  -0.220  -0.124  -0.466  -0.686  -0.505  -0.304  -0.546  -0.414
96    A         0.269   0.082  -0.034   0.059  -0.168  -0.324   0.260  -0.030  -0.253
97    E         0.997   1.034   1.082   1.000   1.057   1.133   1.049   1.099   1.169
98    H        -0.090  -0.220  -0.124   0.021  -0.244  -0.130  -0.304  -0.546  -0.414
99    G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
100   L         0.997   1.034   1.082   0.867   0.924   1.016   1.049   1.099   1.169
101   H         0.997   1.034   1.082   1.150   1.201   1.263   1.049   1.099   1.169
102   A        -0.886  -0.924  -0.799  -1.267  -1.259  -1.028  -1.093  -1.083  -0.908
103   P        -1.078  -1.327  -1.308  -0.958  -1.313  -1.343  -0.981  -1.249  -1.188
104   A        -2.226  -2.192  -2.035  -2.212  -2.109  -1.863  -1.770  -1.702  -1.475
105   Y         0.269   0.082  -0.034   0.448   0.218   0.031   0.260  -0.030  -0.253
106   A        -2.018  -1.864  -1.709  -2.204  -1.948  -1.687  -1.770  -1.586  -1.362
107   W         0.997   1.034   1.082   1.202   1.252   1.308   1.049   1.099   1.169
108   S        -0.886  -0.922  -0.798  -1.041  -1.081  -0.882  -1.093  -1.092  -0.908
109   H        -0.090  -0.168  -0.118   0.070  -0.075  -0.031  -0.304  -0.453  -0.405
110   N        -0.425  -0.723  -0.778  -0.127  -0.562  -0.701  -0.417  -0.805  -0.878
111   G        -0.425  -0.723  -0.778  -0.294  -0.690  -0.766  -0.417  -0.805  -0.878
112   P        -1.430  -1.521  -1.318  -1.300  -1.384  -1.099  -1.432  -1.456  -1.199
113   F        -0.282  -0.087  -0.081  -0.527  -0.224  -0.208  -0.642  -0.310  -0.338
114   E        -1.891  -1.771  -1.701  -1.712  -1.591  -1.442  -1.657  -1.515  -1.356
115   T         0.269   0.082  -0.034   0.374   0.123  -0.096   0.260  -0.030  -0.253
116   F         0.997   1.034   1.082   1.091   1.139   1.211   1.049   1.099   1.169
117   D         0.997   1.034   1.082   1.003   1.064   1.134   1.049   1.099   1.169
118   H         0.997   1.034   1.082   1.150   1.201   1.263   1.049   1.099   1.169
119   A        -0.425  -0.405  -0.741  -0.527  -0.490  -0.889  -0.417  -0.405  -0.829
120   S         0.269   0.142  -0.027   0.310   0.129  -0.199   0.260   0.065  -0.242
121   I        -0.282  -0.267  -0.119  -0.428  -0.484  -0.249  -0.642  -0.632  -0.406
122   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
123   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
124   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
125   Y        -0.282  -0.267  -0.126  -0.370  -0.366  -0.149  -0.642  -0.631  -0.419
126   Q         0.997   1.034   1.082   1.159   1.204   1.270   1.049   1.099   1.169
127   V         0.997   1.034   1.082   0.994   1.049   1.127   1.049   1.099   1.169
128   Y         0.997   1.034   1.082   1.047   1.105   1.173   1.049   1.099   1.169
129   R        -0.425  -0.271  -0.722  -0.187  -0.003  -0.607  -0.417  -0.216  -0.805
130   E         0.997   1.034   1.082   1.000   1.057   1.133   1.049   1.099   1.169
131   V         0.997   1.034   1.082   0.994   1.049   1.127   1.049   1.099   1.169
132   C         0.997   1.034   1.082   1.239   1.285   1.339   1.049   1.099   1.169
133   A         0.269   0.082  -0.034   0.056  -0.173  -0.331   0.260  -0.030  -0.253
134   A         0.269   0.142  -0.027   0.056  -0.088  -0.321   0.260   0.065  -0.242
135   C         0.997   1.034   1.082   1.239   1.285   1.339   1.049   1.099   1.169
136   H         0.997   1.034   1.082   1.150   1.201   1.263   1.049   1.099   1.169
137   S         0.997   1.034   1.082   0.976   1.032   1.111   1.049   1.099   1.169
138   L         0.997   1.034   1.082   0.867   0.924   1.016   1.049   1.099   1.169
139   D        -1.078  -1.222  -1.291  -0.810  -1.035  -1.142  -0.981  -1.149  -1.171
140   R         0.269   0.082  -0.034   0.381   0.120  -0.103   0.260  -0.030  -0.253
141   V        -0.343  -0.267  -0.127  -0.501  -0.384  -0.169  -0.755  -0.632  -0.421
142   A         0.269   0.142  -0.027   0.046  -0.102  -0.350   0.260   0.065  -0.242
143   W         0.269   0.142  -0.027   0.587   0.422   0.123   0.260   0.065  -0.242
144   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
145   T        -1.430  -1.521  -1.318  -1.355  -1.484  -1.218  -1.432  -1.456  -1.199
146   L        -0.090   0.103  -0.060  -0.197   0.075  -0.140  -0.304   0.005  -0.300
147   V         0.997   1.034   1.082   0.994   1.049   1.127   1.049   1.099   1.169
148   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
149   V         0.269   0.142  -0.027   0.374   0.215  -0.057   0.260   0.065  -0.242
150   S        -0.743  -0.901  -0.809  -0.700  -0.938  -0.789  -0.868  -1.060  -0.920
151   H         0.269   0.142  -0.027   0.511   0.335   0.014   0.260   0.065  -0.242
152   T         0.997   1.034   1.082   1.007   1.067   1.138   1.049   1.099   1.169
153   N        -1.430  -1.521  -1.318  -1.392  -1.570  -1.286  -1.432  -1.456  -1.199
154   E        -1.891  -1.455  -1.671  -1.830  -1.186  -1.557  -1.657  -1.200  -1.331
155   E         0.997   1.034   1.082   1.000   1.057   1.133   1.049   1.099   1.169
156   V        -0.282  -0.106  -0.087  -0.745  -0.455  -0.406  -0.642  -0.344  -0.348
157   R        -0.282  -0.106  -0.087  -0.456  -0.163  -0.159  -0.642  -0.344  -0.348
158   N        -1.078  -1.027  -1.267  -1.088  -1.022  -1.252  -0.981  -0.930  -1.146
159   M        -0.743  -0.770  -0.783  -0.535  -0.587  -0.671  -0.868  -0.871  -0.887
160   A         0.997   1.034   1.082   0.682   0.753   0.856   1.049   1.099   1.169
161   E        -0.425  -0.493  -0.748  -0.288  -0.395  -0.851  -0.417  -0.523  -0.840
162   E         0.269   0.440  -0.001   0.380   0.590  -0.009   0.260   0.498  -0.197
163   F        -1.430  -1.521  -1.318  -1.406  -1.510  -1.204  -1.432  -1.456  -1.199
164   E         0.997   1.034   1.082   1.000   1.057   1.133   1.049   1.099   1.169
165   Y         0.997   1.034   1.082   1.047   1.105   1.173   1.049   1.099   1.169
166   D         0.269   0.082  -0.034   0.382   0.141  -0.064   0.260  -0.030  -0.253
167   D         0.269   0.142  -0.027   0.383   0.229  -0.050   0.260   0.065  -0.242
168   E         0.269   0.082  -0.034   0.367   0.113  -0.101   0.260  -0.030  -0.253
169   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
170   D         0.269   0.142  -0.027   0.398   0.250  -0.009   0.260   0.065  -0.242
171   E        -0.090   0.090  -0.057  -0.121   0.153  -0.106  -0.304  -0.017  -0.295
172   Q        -0.343  -0.267  -0.127  -0.463  -0.357  -0.140  -0.755  -0.632  -0.421
173   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
174   N        -0.743  -0.679  -0.759  -0.601  -0.489  -0.663  -0.868  -0.746  -0.854
175   P        -0.425  -0.723  -0.778  -0.276  -0.650  -0.715  -0.417  -0.805  -0.878
176   K        -1.430  -1.521  -1.318  -1.372  -1.466  -1.178  -1.432  -1.456  -1.199
177   K         0.997   1.034   1.082   0.991   1.050   1.125   1.049   1.099   1.169
178   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
179   P         0.269   0.412  -0.005   0.304   0.485  -0.048   0.260   0.460  -0.204
180   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
181   K         0.997   1.034   1.082   0.991   1.050   1.125   1.049   1.099   1.169
182   L         0.997   1.034   1.082   0.867   0.924   1.016   1.049   1.099   1.169
183   S        -0.343  -0.239  -0.117  -0.829  -0.606  -0.414  -0.755  -0.581  -0.402
184   D         0.997   1.034   1.082   1.003   1.064   1.134   1.049   1.099   1.169
185   Y         0.269   0.082  -0.034   0.439   0.202   0.007   0.260  -0.030  -0.253
186   I        -0.743  -0.713  -0.801  -0.645  -0.735  -0.819  -0.868  -0.884  -0.912
187   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
188   G        -1.078  -1.222  -1.291  -0.939  -1.183  -1.282  -0.981  -1.149  -1.171
189   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
190   Y         0.997   1.034   1.082   1.047   1.105   1.173   1.049   1.099   1.169
191   P        -0.743  -0.679  -0.759  -0.790  -0.669  -0.808  -0.868  -0.746  -0.854
192   N         0.997   1.034   1.082   1.111   1.160   1.229   1.049   1.099   1.169
193   E        -0.425  -0.723  -0.778  -0.233  -0.652  -0.770  -0.417  -0.805  -0.878
194   Q        -0.090  -0.220  -0.124   0.029  -0.242  -0.125  -0.304  -0.546  -0.414
195   A         0.997   1.034   1.082   0.682   0.753   0.856   1.049   1.099   1.169
196   A         0.997   1.034   1.082   0.682   0.753   0.856   1.049   1.099   1.169
197   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
198   A         0.269   0.142  -0.027   0.074  -0.062  -0.271   0.260   0.065  -0.242
199   A         0.269   0.082  -0.034   0.056  -0.173  -0.331   0.260  -0.030  -0.253
200   N         0.997   1.034   1.082   1.111   1.160   1.229   1.049   1.099   1.169
201   Q        -0.090  -0.220  -0.124   0.063  -0.187  -0.062  -0.304  -0.546  -0.414
202   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
203   A         0.997   1.034   1.082   0.682   0.753   0.856   1.049   1.099   1.169
204   L        -0.425  -0.442  -0.744  -0.410  -0.497  -0.917  -0.417  -0.465  -0.834
205   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
206   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
207   D         0.997   1.034   1.082   1.003   1.064   1.134   1.049   1.099   1.169
208   L         0.997   1.034   1.082   0.867   0.924   1.016   1.049   1.099   1.169
209   S         0.997   1.034   1.082   0.976   1.032   1.111   1.049   1.099   1.169
210   L         0.269   0.082  -0.034   0.282   0.064  -0.072   0.260  -0.030  -0.253
211   I         0.269   0.082  -0.034   0.491   0.237   0.021   0.260  -0.030  -0.253
212   V         0.269   0.296  -0.015   0.329   0.368  -0.158   0.260   0.297  -0.220
213   K         0.269   0.082  -0.034   0.373   0.132  -0.065   0.260  -0.030  -0.253
214   A         0.269   0.082  -0.034   0.047  -0.189  -0.359   0.260  -0.030  -0.253
215   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
216   H         0.997   1.034   1.082   1.150   1.201   1.263   1.049   1.099   1.169
217   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
218   G         0.269   0.412  -0.005   0.247   0.440  -0.207   0.260   0.460  -0.204
219   C        -1.891  -1.729  -1.691  -1.698  -1.466  -1.461  -1.657  -1.481  -1.348
220   D         0.997   1.034   1.082   1.003   1.064   1.134   1.049   1.099   1.169
221   Y         0.997   1.034   1.082   1.047   1.105   1.173   1.049   1.099   1.169
222   I         0.997   1.034   1.082   1.113   1.163   1.231   1.049   1.099   1.169
223   F         0.269   0.082  -0.034   0.477   0.227   0.024   0.260  -0.030  -0.253
224   S        -0.282  -0.158  -0.109  -0.648  -0.414  -0.389  -0.642  -0.434  -0.387
225   L         0.997   1.034   1.082   0.867   0.924   1.016   1.049   1.099   1.169
226   L         0.997   1.034   1.082   0.867   0.924   1.016   1.049   1.099   1.169
227   T         0.997   1.034   1.082   1.007   1.067   1.138   1.049   1.099   1.169
228   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
229   Y         0.997   1.034   1.082   1.047   1.105   1.173   1.049   1.099   1.169
230   P         0.997   1.034   1.082   0.909   0.975   1.053   1.049   1.099   1.169
231   D        -0.425  -0.460  -0.747  -0.229  -0.297  -0.713  -0.417  -0.485  -0.838
232   E        -0.090   0.097  -0.070  -0.123   0.159  -0.129  -0.304  -0.005  -0.317
233   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
234   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
235   A         0.997   1.034   1.082   0.682   0.753   0.856   1.049   1.099   1.169
236   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
237   V         0.269   0.142  -0.027   0.329   0.147  -0.184   0.260   0.065  -0.242
238   A        -1.683  -1.715  -1.697  -1.450  -1.547  -1.550  -1.432  -1.451  -1.352
239   L        -0.090  -0.220  -0.124  -0.255  -0.489  -0.325  -0.304  -0.546  -0.414
240   P        -0.425  -0.542  -0.753  -0.392  -0.556  -0.960  -0.417  -0.568  -0.846
241   P        -1.348  -1.428  -1.305  -1.404  -1.538  -1.386  -1.319  -1.354  -1.185
242   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
243   S        -1.891  -1.766  -1.702  -1.787  -1.605  -1.568  -1.657  -1.512  -1.357
244   N         0.997   1.034   1.082   1.111   1.160   1.229   1.049   1.099   1.169
245   Y        -0.090  -0.220  -0.124  -0.049  -0.283  -0.147  -0.304  -0.546  -0.414
246   N         0.997   1.034   1.082   1.111   1.160   1.229   1.049   1.099   1.169
247   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
248   Y         0.269   0.082  -0.034   0.439   0.202   0.007   0.260  -0.030  -0.253
249   F         0.997   1.034   1.082   1.091   1.139   1.211   1.049   1.099   1.169
250   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
251   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
252   G        -0.090  -0.220  -0.124  -0.206  -0.436  -0.286  -0.304  -0.546  -0.414
253   S        -1.556  -1.530  -1.320  -1.831  -1.711  -1.385  -1.544  -1.464  -1.201
254   I         0.997   1.034   1.082   1.113   1.163   1.231   1.049   1.099   1.169
255   A        -0.425  -0.297  -0.727  -0.572  -0.394  -0.973  -0.417  -0.247  -0.812
256   M         0.997   1.034   1.082   1.168   1.217   1.278   1.049   1.099   1.169
257   A        -0.090   0.141  -0.064  -0.464  -0.103  -0.409  -0.304   0.064  -0.306
258   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
259   V        -0.425  -0.595  -0.761  -0.253  -0.503  -0.779  -0.417  -0.643  -0.856
260   L         0.997   1.034   1.082   0.867   0.924   1.016   1.049   1.099   1.169
261   F         0.269   0.142  -0.027   0.477   0.311   0.036   0.260   0.065  -0.242
262   D         0.997   1.034   1.082   1.003   1.064   1.134   1.049   1.099   1.169
263   D        -0.090  -0.138  -0.115  -0.149  -0.248  -0.260  -0.304  -0.400  -0.398
264   M        -1.078  -1.119  -1.276  -0.991  -1.125  -1.304  -0.981  -1.029  -1.156
265   V         0.997   1.034   1.082   0.994   1.049   1.127   1.049   1.099   1.169
266   E         0.269   0.142  -0.027   0.380   0.222  -0.053   0.260   0.065  -0.242
267   Y         0.269   0.082  -0.034   0.439   0.202   0.007   0.260  -0.030  -0.253
268   E         0.997   1.034   1.082   1.000   1.057   1.133   1.049   1.099   1.169
269   D         0.997   1.034   1.082   1.003   1.064   1.134   1.049   1.099   1.169
270   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
271   T         0.997   1.034   1.082   1.007   1.067   1.138   1.049   1.099   1.169
272   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
273   A         0.997   1.034   1.082   0.682   0.753   0.856   1.049   1.099   1.169
274   T         0.269   0.142  -0.027   0.383   0.224  -0.059   0.260   0.065  -0.242
275   T         0.997   1.034   1.082   1.007   1.067   1.138   1.049   1.099   1.169
276   S         0.269   0.082  -0.034   0.310   0.034  -0.213   0.260  -0.030  -0.253
277   Q         0.997   1.034   1.082   1.159   1.204   1.270   1.049   1.099   1.169
278   M         0.269   0.082  -0.034   0.503   0.219  -0.056   0.260  -0.030  -0.253
279   A         0.997   1.034   1.082   0.682   0.753   0.856   1.049   1.099   1.169
280   K         0.997   1.034   1.082   0.991   1.050   1.125   1.049   1.099   1.169
281   D         0.997   1.034   1.082   1.003   1.064   1.134   1.049   1.099   1.169
282   V         0.997   1.034   1.082   0.994   1.049   1.127   1.049   1.099   1.169
283   T        -1.348  -1.256  -1.307  -1.321  -1.258  -1.336  -1.319  -1.231  -1.189
284   T        -1.078  -1.327  -1.308  -0.861  -1.231  -1.283  -0.981  -1.249  -1.188
285   F         0.997   1.034   1.082   1.091   1.139   1.211   1.049   1.099   1.169
286   L         0.997   1.034   1.082   0.867   0.924   1.016   1.049   1.099   1.169
287   N        -0.743  -0.753  -0.792  -0.541  -0.576  -0.645  -0.868  -0.879  -0.900
288   W         0.997   1.034   1.082   1.202   1.252   1.308   1.049   1.099   1.169
289   C        -0.282  -0.106  -0.087  -0.605  -0.354  -0.277  -0.642  -0.344  -0.348
290   A        -0.343  -0.268  -0.127  -0.829  -0.710  -0.461  -0.755  -0.633  -0.420
291   E         0.997   1.034   1.082   1.000   1.057   1.133   1.049   1.099   1.169
292   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
293   E         0.997   1.034   1.082   1.000   1.057   1.133   1.049   1.099   1.169
294   H        -0.425  -0.723  -0.778  -0.078  -0.511  -0.649  -0.417  -0.805  -0.878
295   D         0.997   1.034   1.082   1.003   1.064   1.134   1.049   1.099   1.169
296   E        -0.886  -0.950  -0.803  -0.938  -0.991  -0.770  -1.093  -1.120  -0.914
297   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
298   K         0.997   1.034   1.082   0.991   1.050   1.125   1.049   1.099   1.169
299   R        -0.282  -0.209  -0.119  -0.456  -0.344  -0.218  -0.642  -0.526  -0.407
300   L        -1.556  -1.369  -1.314  -1.554  -1.265  -1.223  -1.544  -1.327  -1.195
301   G         0.997   1.034   1.082   0.912   0.973   1.056   1.049   1.099   1.169
302   L        -0.425  -0.723  -0.778  -0.321  -0.703  -0.752  -0.417  -0.805  -0.878
303   K         0.269   0.082  -0.034   0.394   0.165  -0.008   0.260  -0.030  -0.253
304   T        -0.743  -0.729  -0.800  -1.007  -1.016  -1.011  -0.868  -0.899  -0.911
305   V        -1.348  -1.169  -1.291  -1.279  -1.084  -1.144  -1.319  -1.144  -1.174
306   I        -1.348  -1.365  -1.303  -1.177  -1.240  -1.183  -1.319  -1.316  -1.185
307   I        -0.743  -0.470  -0.750  -0.689  -0.307  -0.725  -0.868  -0.489  -0.843
308   L        -1.078  -1.063  -1.268  -0.938  -0.935  -1.190  -0.981  -0.960  -1.148
309   S         0.269   0.082  -0.034   0.356   0.112  -0.083   0.260  -0.030  -0.253
310   S        -1.078  -1.327  -1.308  -0.893  -1.264  -1.305  -0.981  -1.249  -1.188
311   L         0.269   0.296  -0.015   0.271   0.315  -0.074   0.260   0.297  -0.220
312   Y        -1.078  -1.327  -1.308  -0.790  -1.164  -1.189  -0.981  -1.249  -1.188
313   L        -0.743  -0.824  -0.808  -0.969  -1.200  -1.135  -0.868  -0.991  -0.920
314   L         0.269   0.440  -0.001   0.245   0.456  -0.120   0.260   0.498  -0.197
315   S         0.997   1.034   1.082   0.976   1.032   1.111   1.049   1.099   1.169
316   I        -0.743  -0.735  -0.774  -0.633  -0.595  -0.655  -0.868  -0.821  -0.875
317   W        -0.090  -0.138  -0.115   0.085  -0.020  -0.048  -0.304  -0.400  -0.398
318   V        -0.425  -0.595  -0.761  -0.212  -0.444  -0.682  -0.417  -0.643  -0.856
319   K         0.997   1.034   1.082   0.991   1.050   1.125   1.049   1.099   1.169
320   K        -0.282  -0.267  -0.126  -0.456  -0.451  -0.229  -0.642  -0.631  -0.419
321   F         0.269   0.142  -0.027   0.477   0.311   0.036   0.260   0.065  -0.242
322   K         0.997   1.034   1.082   0.991   1.050   1.125   1.049   1.099   1.169
323   W         0.997   1.034   1.082   1.202   1.252   1.308   1.049   1.099   1.169
324   A        -1.348  -1.233  -1.293  -1.504  -1.362  -1.323  -1.319  -1.187  -1.176
325   G        -1.683  -1.472  -1.674  -1.544  -1.238  -1.586  -1.432  -1.206  -1.333
326   I         0.269   0.142  -0.027   0.474   0.297  -0.016   0.260   0.065  -0.242
327   K         0.997   1.034   1.082   0.991   1.050   1.125   1.049   1.099   1.169
328   T        -0.743  -0.615  -0.779  -0.605  -0.463  -0.712  -0.868  -0.715  -0.884
329   R         0.997   1.034   1.082   1.021   1.076   1.150   1.049   1.099   1.169
330   K         0.997   1.034   1.082   0.991   1.050   1.125   1.049   1.099   1.169
331   F        -0.343  -0.247  -0.118  -0.431  -0.284  -0.092  -0.755  -0.595  -0.404
332   V        -1.348  -1.331  -1.294  -1.199  -1.156  -1.101  -1.319  -1.254  -1.174
333   F        -0.282  -0.267  -0.119  -0.355  -0.368  -0.139  -0.642  -0.632  -0.406
334   N        -0.886  -0.950  -0.803  -0.839  -0.901  -0.688  -1.093  -1.120  -0.914
335   P         0.269   0.082  -0.034   0.290   0.055  -0.131   0.260  -0.030  -0.253
336   P         0.997   1.034   1.082   0.908   0.971   1.052   1.049   1.099   1.169
337   K        -0.425  -0.468  -0.743  -0.226  -0.295  -0.683  -0.417  -0.495  -0.833
338   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
339   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
340   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
341   P        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
342   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
343   K        -0.425  -0.542  -0.753  -0.197  -0.342  -0.633  -0.417  -0.568  -0.846
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P07143
Output conservation file - output/P07143
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
