1     M         0.764   0.774   0.835   1.070   1.084   1.120   0.795   0.808   0.893
2     S        -2.218  -2.195  -1.983  -2.205  -2.150  -1.884  -1.992  -1.953  -1.624
3     Q        -1.755  -1.812  -1.601  -1.601  -1.715  -1.426  -1.716  -1.782  -1.473
4     Q        -1.575  -1.605  -1.591  -1.395  -1.450  -1.522  -1.511  -1.543  -1.464
5     V        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     N        -0.861  -0.821  -1.049  -0.766  -0.740  -1.005  -0.938  -0.905  -1.152
10    S        -1.323  -1.272  -1.084  -1.551  -1.479  -1.193  -1.540  -1.471  -1.195
11    I        -0.600  -0.570  -0.381  -0.977  -0.935  -0.603  -1.013  -0.962  -0.679
12    R         0.764   0.774   0.835   0.809   0.825   0.906   0.795   0.808   0.893
13    R         0.764   0.774   0.835   0.809   0.825   0.906   0.795   0.808   0.893
14    K         0.764   0.774   0.835   0.677   0.686   0.797   0.795   0.808   0.893
15    L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
16    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
17    I         0.764   0.774   0.835   0.826   0.842   0.919   0.795   0.808   0.893
18    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
19    G         0.764   0.774   0.835   0.746   0.767   0.854   0.795   0.808   0.893
20    D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
21    G         0.764   0.774   0.835   0.746   0.767   0.854   0.795   0.808   0.893
22    A         0.764   0.774   0.835   0.729   0.743   0.840   0.795   0.808   0.893
23    C         0.764   0.774   0.835   0.919   0.933   0.996   0.795   0.808   0.893
24    G         0.764   0.774   0.835   0.746   0.767   0.854   0.795   0.808   0.893
25    K         0.764   0.774   0.835   0.677   0.686   0.797   0.795   0.808   0.893
26    T         0.764   0.774   0.835   0.843   0.858   0.933   0.795   0.808   0.893
27    C         0.764   0.774   0.835   0.919   0.933   0.996   0.795   0.808   0.893
28    L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
29    L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
30    I         0.764   0.774   0.835   0.826   0.842   0.919   0.795   0.808   0.893
31    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
32    F         0.764   0.774   0.835   0.944   0.957   1.016   0.795   0.808   0.893
33    S        -0.474  -0.469  -0.376  -0.619  -0.619  -0.521  -0.787  -0.780  -0.670
34    K         0.764   0.774   0.835   0.677   0.686   0.797   0.795   0.808   0.893
35    G         0.764   0.774   0.835   0.746   0.767   0.854   0.795   0.808   0.893
36    Q        -0.861  -0.833  -1.054  -0.686  -0.636  -1.036  -0.938  -0.881  -1.158
37    F         0.764   0.774   0.835   0.944   0.957   1.016   0.795   0.808   0.893
38    P         0.764   0.774   0.835   0.849   0.862   0.938   0.795   0.808   0.893
39    E         0.105   0.048  -0.311   0.158   0.092  -0.400   0.117   0.038  -0.555
40    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
41    Y         0.764   0.774   0.835   0.949   0.964   1.021   0.795   0.808   0.893
42    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
43    P         0.764   0.774   0.835   0.849   0.862   0.938   0.795   0.808   0.893
44    T         0.764   0.774   0.835   0.843   0.858   0.933   0.795   0.808   0.893
45    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
46    F         0.764   0.774   0.835   0.944   0.957   1.016   0.795   0.808   0.893
47    E        -0.250  -0.264  -0.363  -0.330  -0.357  -0.549  -0.410  -0.434  -0.646
48    N         0.764   0.774   0.835   0.971   0.986   1.039   0.795   0.808   0.893
49    Y         0.764   0.774   0.835   0.949   0.964   1.021   0.795   0.808   0.893
50    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
51    A         0.105   0.148  -0.304   0.191   0.240  -0.376   0.117   0.174  -0.543
52    D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
53    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
54    E         0.764   0.774   0.835   0.691   0.703   0.809   0.795   0.808   0.893
55    V        -0.250  -0.203  -0.334  -0.504  -0.439  -0.603  -0.410  -0.336  -0.596
56    D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
57    G         0.764   0.774   0.835   0.746   0.767   0.854   0.795   0.808   0.893
58    R         0.764   0.774   0.835   0.809   0.825   0.906   0.795   0.808   0.893
59    R        -1.323  -1.308  -1.088  -1.348  -1.327  -1.036  -1.540  -1.530  -1.201
60    V         0.105   0.022  -0.308  -0.044  -0.143  -0.563   0.117   0.001  -0.551
61    E         0.764   0.774   0.835   0.691   0.703   0.809   0.795   0.808   0.893
62    L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
63    A         0.764   0.774   0.835   0.729   0.743   0.840   0.795   0.808   0.893
64    L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
65    W         0.764   0.774   0.835   1.056   1.071   1.109   0.795   0.808   0.893
66    D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
67    T         0.764   0.774   0.835   0.843   0.858   0.933   0.795   0.808   0.893
68    A         0.764   0.774   0.835   0.729   0.743   0.840   0.795   0.808   0.893
69    G         0.764   0.774   0.835   0.746   0.767   0.854   0.795   0.808   0.893
70    Q         0.764   0.774   0.835   0.880   0.904   0.963   0.795   0.808   0.893
71    E         0.764   0.774   0.835   0.691   0.703   0.809   0.795   0.808   0.893
72    D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
73    Y         0.764   0.774   0.835   0.949   0.964   1.021   0.795   0.808   0.893
74    D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
75    R         0.764   0.774   0.835   0.809   0.825   0.906   0.795   0.808   0.893
76    L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
77    R         0.764   0.774   0.835   0.809   0.825   0.906   0.795   0.808   0.893
78    P         0.764   0.774   0.835   0.849   0.862   0.938   0.795   0.808   0.893
79    L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
80    S         0.764   0.774   0.835   0.786   0.798   0.887   0.795   0.808   0.893
81    Y         0.764   0.774   0.835   0.949   0.964   1.021   0.795   0.808   0.893
82    P         0.764   0.774   0.835   0.849   0.862   0.938   0.795   0.808   0.893
83    D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
84    S         0.105   0.141  -0.304   0.236   0.276  -0.379   0.117   0.166  -0.543
85    N        -0.474  -0.534  -0.376  -0.327  -0.434  -0.244  -0.787  -0.896  -0.671
86    V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
87    V        -0.641  -0.623  -0.385  -1.097  -1.090  -0.664  -1.088  -1.059  -0.686
88    L        -0.250  -0.203  -0.334  -0.409  -0.346  -0.534  -0.410  -0.336  -0.596
89    I         0.764   0.774   0.835   0.826   0.842   0.919   0.795   0.808   0.893
90    C         0.764   0.774   0.835   0.919   0.933   0.996   0.795   0.808   0.893
91    F         0.105   0.048  -0.311   0.417   0.353  -0.189   0.117   0.038  -0.555
92    S        -0.600  -0.598  -0.383  -0.866  -0.877  -0.536  -1.013  -1.013  -0.683
93    I        -0.474  -0.467  -0.372  -0.672  -0.668  -0.603  -0.787  -0.778  -0.662
94    D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
95    L        -1.056  -1.102  -1.068  -1.185  -1.239  -1.210  -1.239  -1.274  -1.177
96    P         0.764   0.774   0.835   0.849   0.862   0.938   0.795   0.808   0.893
97    D         0.105   0.022  -0.308   0.194   0.093  -0.430   0.117   0.001  -0.551
98    S         0.764   0.774   0.835   0.786   0.798   0.887   0.795   0.808   0.893
99    L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
100   E        -0.474  -0.441  -0.366  -0.669  -0.615  -0.544  -0.787  -0.731  -0.651
101   N         0.764   0.774   0.835   0.971   0.986   1.039   0.795   0.808   0.893
102   V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
103   Q        -1.443  -1.534  -1.572  -1.192  -1.281  -1.403  -1.390  -1.469  -1.446
104   E         0.764   0.774   0.835   0.691   0.703   0.809   0.795   0.808   0.893
105   K         0.764   0.774   0.835   0.677   0.686   0.797   0.795   0.808   0.893
106   W         0.764   0.774   0.835   1.056   1.071   1.109   0.795   0.808   0.893
107   I         0.105  -0.009  -0.316   0.309   0.183  -0.248   0.117  -0.043  -0.564
108   A        -0.250  -0.154  -0.331  -0.241  -0.104  -0.430  -0.410  -0.260  -0.590
109   E         0.764   0.774   0.835   0.691   0.703   0.809   0.795   0.808   0.893
110   V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
111   L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
112   H         0.764   0.774   0.835   1.032   1.042   1.088   0.795   0.808   0.893
113   F         0.764   0.774   0.835   0.944   0.957   1.016   0.795   0.808   0.893
114   C         0.764   0.774   0.835   0.919   0.933   0.996   0.795   0.808   0.893
115   Q        -0.861  -0.999  -1.063  -0.659  -0.844  -1.018  -0.938  -1.108  -1.169
116   G        -1.142  -1.301  -1.564  -0.852  -1.052  -1.441  -1.013  -1.196  -1.437
117   V        -0.250  -0.286  -0.345  -0.565  -0.630  -0.734  -0.410  -0.470  -0.616
118   P         0.764   0.774   0.835   0.849   0.862   0.938   0.795   0.808   0.893
119   I         0.764   0.774   0.835   0.826   0.842   0.919   0.795   0.808   0.893
120   I        -0.600  -0.592  -0.380  -0.909  -0.906  -0.578  -1.013  -1.002  -0.678
121   L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
122   V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
123   G         0.105   0.139  -0.306   0.195   0.242  -0.412   0.117   0.163  -0.546
124   C         0.764   0.774   0.835   0.919   0.933   0.996   0.795   0.808   0.893
125   K         0.764   0.774   0.835   0.677   0.686   0.797   0.795   0.808   0.893
126   V        -1.710  -1.762  -1.584  -1.972  -2.053  -1.740  -1.691  -1.730  -1.458
127   D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
128   L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
129   R         0.764   0.774   0.835   0.809   0.825   0.906   0.795   0.808   0.893
130   N        -0.531  -0.575  -1.035  -0.089  -0.140  -0.838  -0.485  -0.546  -1.134
131   D         0.764   0.774   0.835   0.749   0.764   0.856   0.795   0.808   0.893
132   P         0.105   0.151  -0.305   0.315   0.368  -0.275   0.117   0.179  -0.544
133   Q        -1.604  -1.500  -1.583  -1.525  -1.410  -1.362  -1.616  -1.505  -1.457
134   T        -0.531  -0.563  -1.031  -0.272  -0.318  -1.085  -0.485  -0.525  -1.128
135   I        -0.531  -0.536  -1.030  -0.318  -0.329  -1.188  -0.485  -0.493  -1.127
136   E         0.105   0.151  -0.305   0.175   0.223  -0.328   0.117   0.179  -0.544
137   Q        -1.056  -0.930  -1.062  -1.139  -0.962  -1.122  -1.239  -1.069  -1.169
138   L         0.764   0.774   0.835   0.591   0.603   0.727   0.795   0.808   0.893
139   R        -0.474  -0.479  -0.372  -0.574  -0.590  -0.468  -0.787  -0.798  -0.663
140   Q        -2.005  -1.972  -1.603  -2.134  -2.107  -1.557  -1.992  -1.952  -1.475
141   E        -1.323  -1.245  -1.086  -1.393  -1.268  -1.084  -1.540  -1.440  -1.198
142   G        -1.830  -1.757  -1.592  -1.825  -1.723  -1.429  -1.842  -1.759  -1.465
143   Q        -0.250  -0.253  -0.346  -0.182  -0.182  -0.456  -0.410  -0.416  -0.618
144   Q        -1.710  -1.739  -1.590  -1.560  -1.643  -1.414  -1.691  -1.731  -1.464
145   P         0.764   0.774   0.835   0.849   0.862   0.938   0.795   0.808   0.893
146   V         0.105   0.022  -0.308  -0.044  -0.143  -0.563   0.117   0.001  -0.551
147   T        -1.148  -1.108  -1.071  -1.230  -1.198  -1.091  -1.390  -1.352  -1.182
148   S        -1.724  -1.874  -1.964  -1.253  -1.455  -1.622  -1.465  -1.621  -1.608
149   Q        -1.710  -1.601  -1.588  -1.749  -1.610  -1.553  -1.691  -1.573  -1.461
150   E        -0.531  -0.536  -1.030  -0.386  -0.394  -1.072  -0.485  -0.493  -1.127
151   G         0.105   0.048  -0.311   0.195   0.134  -0.422   0.117   0.038  -0.555
152   Q        -0.861  -0.927  -1.055  -0.623  -0.699  -0.970  -0.938  -1.004  -1.159
153   S        -2.272  -2.230  -2.295  -1.950  -1.932  -2.058  -1.842  -1.803  -1.725
154   V         0.105  -0.009  -0.316  -0.072  -0.218  -0.678   0.117  -0.043  -0.564
155   A         0.105  -0.009  -0.316   0.187   0.051  -0.411   0.117  -0.043  -0.564
156   D        -1.056  -1.127  -1.074  -1.035  -1.115  -1.109  -1.239  -1.301  -1.184
157   Q        -1.323  -1.325  -1.094  -1.493  -1.501  -1.144  -1.540  -1.536  -1.207
158   I         0.764   0.774   0.835   0.826   0.842   0.919   0.795   0.808   0.893
159   G         0.105  -0.009  -0.316   0.223   0.099  -0.330   0.117  -0.043  -0.564
160   A         0.105   0.151  -0.305   0.191   0.244  -0.378   0.117   0.179  -0.544
161   T        -3.342  -3.323  -2.827  -2.962  -2.929  -2.369  -2.445  -2.422  -1.874
162   G        -1.710  -1.615  -1.587  -1.757  -1.626  -1.542  -1.691  -1.580  -1.461
163   Y         0.764   0.774   0.835   0.949   0.964   1.021   0.795   0.808   0.893
164   Y        -0.861  -0.833  -1.054  -0.890  -0.846  -1.109  -0.938  -0.881  -1.158
165   E         0.764   0.774   0.835   0.691   0.703   0.809   0.795   0.808   0.893
166   C         0.764   0.774   0.835   0.919   0.933   0.996   0.795   0.808   0.893
167   S         0.764   0.774   0.835   0.786   0.798   0.887   0.795   0.808   0.893
168   A         0.764   0.774   0.835   0.729   0.743   0.840   0.795   0.808   0.893
169   K        -0.474  -0.426  -0.366  -0.689  -0.618  -0.533  -0.787  -0.706  -0.651
170   T         0.105   0.022  -0.308   0.278   0.173  -0.399   0.117   0.001  -0.551
171   G        -1.323  -1.326  -1.089  -1.312  -1.322  -0.956  -1.540  -1.551  -1.202
172   Y        -1.830  -1.744  -1.589  -1.862  -1.761  -1.496  -1.842  -1.753  -1.462
173   G         0.764   0.774   0.835   0.746   0.767   0.854   0.795   0.808   0.893
174   V         0.764   0.774   0.835   0.496   0.509   0.649   0.795   0.808   0.893
175   R         0.105   0.022  -0.308   0.286   0.193  -0.273   0.117   0.001  -0.551
176   E         0.764   0.774   0.835   0.691   0.703   0.809   0.795   0.808   0.893
177   V         0.105   0.148  -0.304  -0.044   0.004  -0.556   0.117   0.174  -0.543
178   F         0.764   0.774   0.835   0.944   0.957   1.016   0.795   0.808   0.893
179   E         0.764   0.774   0.835   0.691   0.703   0.809   0.795   0.808   0.893
180   A        -1.991  -2.093  -1.981  -1.679  -1.807  -1.635  -1.766  -1.851  -1.623
181   A         0.764   0.774   0.835   0.729   0.743   0.840   0.795   0.808   0.893
182   T         0.105   0.022  -0.308   0.292   0.192  -0.345   0.117   0.001  -0.551
183   R         0.764   0.774   0.835   0.809   0.825   0.906   0.795   0.808   0.893
184   A         0.764   0.774   0.835   0.729   0.743   0.840   0.795   0.808   0.893
185   S        -0.600  -0.598  -0.383  -0.866  -0.877  -0.536  -1.013  -1.013  -0.683
186   L        -0.250  -0.286  -0.345  -0.345  -0.398  -0.435  -0.410  -0.470  -0.616
187   M        -2.955  -2.857  -2.586  -2.733  -2.652  -2.267  -2.294  -2.209  -1.814
188   G        -1.173  -1.184  -1.081  -1.346  -1.388  -1.236  -1.357  -1.382  -1.192
189   K        -1.286  -1.339  -1.094  -1.319  -1.386  -0.994  -1.507  -1.566  -1.208
190   S        -1.931  -1.894  -1.604  -2.048  -2.010  -1.577  -1.925  -1.887  -1.476
191   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
192   T        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
193   N        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
194   G        -1.272  -1.244  -1.089  -1.388  -1.349  -1.084  -1.511  -1.477  -1.203
195   K        -0.067  -0.169  -0.337  -0.092  -0.240  -0.530  -0.127  -0.283  -0.601
196   A        -2.378  -2.286  -1.989  -2.523  -2.381  -2.001  -2.126  -2.044  -1.629
197   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
198   K        -0.995  -0.938  -1.072  -0.996  -0.925  -1.139  -1.088  -1.011  -1.180
199   K        -2.129  -2.064  -1.976  -2.101  -2.033  -1.921  -1.902  -1.852  -1.619
200   N        -2.218  -2.181  -1.980  -2.170  -2.144  -1.854  -1.992  -1.941  -1.622
201   T        -1.830  -1.826  -1.580  -1.855  -1.827  -1.486  -1.842  -1.815  -1.455
202   T        -1.710  -1.578  -1.577  -1.763  -1.587  -1.557  -1.691  -1.544  -1.452
203   E        -2.674  -2.608  -2.314  -2.574  -2.453  -2.080  -2.218  -2.150  -1.738
204   K        -1.056  -1.057  -1.065  -1.232  -1.216  -1.206  -1.239  -1.213  -1.173
205   K        -0.531  -0.614  -1.034  -0.410  -0.520  -1.117  -0.485  -0.593  -1.132
206   K         0.105  -0.009  -0.316   0.128  -0.015  -0.475   0.117  -0.043  -0.564
207   K        -0.531  -0.590  -1.033  -0.430  -0.522  -1.176  -0.485  -0.564  -1.131
208   K        -1.142  -1.301  -1.564  -0.884  -1.082  -1.387  -1.013  -1.196  -1.437
209   C         0.105  -0.009  -0.316   0.363   0.220  -0.325   0.117  -0.043  -0.564
210   V        -1.443  -1.545  -1.573  -1.571  -1.720  -1.721  -1.390  -1.504  -1.446
211   L        -1.830  -1.871  -1.590  -2.193  -2.246  -1.749  -1.842  -1.862  -1.463
212   L         0.105  -0.009  -0.316   0.014  -0.137  -0.646   0.117  -0.043  -0.564
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P06780
Output conservation file - output/P06780
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
