1     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
2     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
3     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
4     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
5     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
6     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
7     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
8     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
9     -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
10    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
11    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
12    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
13    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
14    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
15    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
16    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
17    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
18    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
19    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
20    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
21    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
22    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
23    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
24    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
25    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
26    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
27    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
28    M         1.298   1.311   1.363   1.403   1.424   1.501   1.385   1.404   1.478
29    G         1.298   1.311   1.363   1.261   1.281   1.366   1.385   1.404   1.478
30    W         1.298   1.311   1.363   1.420   1.440   1.517   1.385   1.404   1.478
31    F         1.298   1.311   1.363   1.383   1.405   1.482   1.385   1.404   1.478
32    W         1.298   1.311   1.363   1.420   1.440   1.517   1.385   1.404   1.478
33    A         0.593   0.590   0.376   0.641   0.624   0.306   0.569   0.563   0.183
34    D         0.593   0.590   0.376   0.572   0.576   0.251   0.569   0.563   0.183
35    Q        -0.686  -0.792  -0.856  -0.556  -0.708  -0.813  -0.655  -0.780  -0.833
36    K        -1.368  -1.335  -1.268  -1.405  -1.342  -1.243  -1.199  -1.160  -1.048
37    T        -1.239  -1.260  -1.251  -1.183  -1.230  -1.201  -1.063  -1.083  -1.031
38    T        -1.386  -1.377  -1.282  -1.363  -1.362  -1.235  -1.206  -1.191  -1.058
39    G        -1.386  -1.332  -1.268  -1.427  -1.342  -1.263  -1.206  -1.147  -1.046
40    K        -1.784  -1.750  -1.604  -1.698  -1.653  -1.438  -1.391  -1.354  -1.181
41    -        -0.993  -0.931  -0.893  -1.064  -0.969  -0.921  -1.014  -0.938  -0.874
42    -        -0.490  -0.422  -0.415  -0.766  -0.658  -0.643  -0.697  -0.600  -0.594
43    -        -1.086  -1.060  -0.932  -1.090  -1.053  -0.862  -1.114  -1.079  -0.915
44    -        -1.086  -1.060  -0.932  -1.110  -1.073  -0.881  -1.114  -1.079  -0.915
45    -        -0.490  -0.455  -0.413  -0.700  -0.642  -0.568  -0.697  -0.647  -0.592
46    -         0.106   0.127   0.218  -0.174  -0.153   0.001  -0.281  -0.246  -0.112
47    -        -0.490  -0.455  -0.413  -0.774  -0.708  -0.668  -0.697  -0.647  -0.592
48    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
49    -        -0.490  -0.488  -0.423  -0.687  -0.684  -0.600  -0.697  -0.695  -0.604
50    D         0.437   0.495   0.348   0.395   0.486   0.267   0.319   0.412   0.132
51    I        -0.336  -0.357  -0.377  -0.227  -0.266  -0.323  -0.481  -0.512  -0.541
52    G        -0.989  -0.944  -0.896  -1.151  -1.085  -1.003  -1.021  -0.969  -0.880
53    G        -0.989  -0.965  -0.894  -1.061  -1.026  -0.907  -1.021  -0.988  -0.878
54    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
55    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
56    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
57    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
58    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
59    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
60    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
61    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
62    A        -0.194  -0.134  -0.323   0.048   0.138  -0.206  -0.281  -0.196  -0.466
63    A        -0.194  -0.134  -0.323  -0.301  -0.219  -0.500  -0.281  -0.196  -0.466
64    V        -0.839  -0.861  -0.866  -0.735  -0.762  -0.788  -0.836  -0.861  -0.844
65    -        -0.993  -0.985  -0.909  -0.970  -0.943  -0.824  -1.014  -1.001  -0.891
66    -        -0.839  -0.862  -0.865  -0.582  -0.635  -0.663  -0.836  -0.865  -0.844
67    -        -0.839  -0.837  -0.875  -0.881  -0.887  -0.949  -0.836  -0.837  -0.855
68    -        -0.989  -0.932  -0.897  -1.095  -1.000  -0.959  -1.021  -0.960  -0.881
69    -         0.331   0.246   0.261   0.426   0.290   0.288   0.136  -0.022  -0.029
70    -        -0.490  -0.546  -0.449  -0.667  -0.771  -0.633  -0.697  -0.773  -0.640
71    -         0.106   0.124   0.216  -0.203  -0.186  -0.021  -0.281  -0.252  -0.116
72    -        -0.490  -0.480  -0.429  -0.537  -0.523  -0.468  -0.697  -0.688  -0.613
73    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
74    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
75    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
76    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
77    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
78    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
79    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
80    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
81    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
82    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
83    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
84    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
85    -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
86    -        -0.516  -0.442  -0.426  -0.840  -0.738  -0.690  -0.747  -0.654  -0.612
87    -        -1.086  -1.063  -0.932  -1.278  -1.240  -1.040  -1.114  -1.082  -0.915
88    -        -1.086  -1.063  -0.932  -1.225  -1.199  -0.990  -1.114  -1.082  -0.915
89    S        -0.346  -0.299  -0.386  -0.469  -0.426  -0.516  -0.519  -0.471  -0.561
90    S        -1.027  -0.966  -0.909  -1.208  -1.123  -1.007  -1.063  -0.998  -0.894
91    M        -0.898  -0.818  -0.869  -1.013  -0.905  -0.938  -0.927  -0.836  -0.852
92    S        -0.072  -0.064  -0.307  -0.045  -0.032  -0.391  -0.111  -0.099  -0.444
93    G        -0.898  -0.904  -0.887  -0.930  -0.954  -0.909  -0.927  -0.933  -0.871
94    C         1.298   1.311   1.363   1.509   1.528   1.601   1.385   1.404   1.478
95    P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
96    V         0.269   0.374   0.320   0.237   0.398   0.309   0.025   0.207   0.080
97    M        -1.368  -1.345  -1.276  -1.316  -1.265  -1.180  -1.199  -1.172  -1.054
98    H         0.593   0.615   0.387   0.838   0.870   0.520   0.569   0.603   0.203
99    E        -0.898  -0.892  -0.887  -1.046  -1.042  -1.025  -0.927  -0.921  -0.872
100   S        -1.239  -1.260  -1.251  -1.185  -1.218  -1.236  -1.063  -1.083  -1.031
101   S        -1.027  -1.001  -0.909  -1.190  -1.133  -0.989  -1.063  -1.026  -0.892
102   S        -1.708  -1.652  -1.579  -1.672  -1.609  -1.480  -1.335  -1.283  -1.163
103   S        -0.346  -0.365  -0.395  -0.450  -0.488  -0.507  -0.519  -0.555  -0.574
104   S        -1.386  -1.368  -1.276  -1.431  -1.400  -1.265  -1.206  -1.184  -1.053
105   P        -1.470  -1.443  -1.302  -1.591  -1.549  -1.336  -1.280  -1.246  -1.074
106   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
107   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
108   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
109   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
110   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
111   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
112   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
113   P         1.298   1.311   1.363   1.128   1.147   1.240   1.385   1.404   1.478
114   S        -0.516  -0.531  -0.429  -0.721  -0.736  -0.579  -0.747  -0.758  -0.615
115   S        -0.490  -0.496  -0.423  -0.640  -0.640  -0.543  -0.697  -0.705  -0.604
116   E        -0.490  -0.424  -0.415  -0.763  -0.660  -0.638  -0.697  -0.603  -0.594
117   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
118   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
119   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
120   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
121   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
122   C         0.437   0.336   0.302   0.668   0.510   0.423   0.319   0.140   0.047
123   P         1.298   1.311   1.363   1.139   1.157   1.251   1.385   1.404   1.478
124   V        -0.336  -0.347  -0.387  -0.286  -0.333  -0.385  -0.481  -0.504  -0.555
125   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
126   M        -0.490  -0.499  -0.427  -0.612  -0.636  -0.518  -0.697  -0.709  -0.610
127   Q        -1.086  -1.061  -0.932  -1.179  -1.148  -0.947  -1.114  -1.080  -0.915
128   G        -1.239  -1.206  -1.241  -1.217  -1.185  -1.235  -1.063  -1.031  -1.022
129   D        -1.239  -1.287  -1.261  -1.170  -1.256  -1.201  -1.063  -1.106  -1.040
130   -        -0.839  -0.909  -0.891  -0.815  -0.958  -0.963  -0.836  -0.915  -0.872
131   N        -0.898  -0.915  -0.871  -0.942  -0.949  -0.904  -0.927  -0.928  -0.852
132   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
133   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
134   D        -1.368  -1.332  -1.270  -1.375  -1.321  -1.203  -1.199  -1.154  -1.049
135   R        -1.368  -1.320  -1.273  -1.385  -1.306  -1.253  -1.199  -1.143  -1.051
136   I        -0.072  -0.057  -0.308   0.048   0.079  -0.278  -0.111  -0.090  -0.445
137   N         1.298   1.311   1.363   1.353   1.372   1.453   1.385   1.404   1.478
138   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
139   L         1.298   1.311   1.363   1.264   1.291   1.369   1.385   1.404   1.478
140   N         1.298   1.311   1.363   1.353   1.372   1.453   1.385   1.404   1.478
141   N        -0.072  -0.195  -0.339   0.146  -0.019  -0.231  -0.111  -0.285  -0.489
142   M         0.593   0.635   0.383   0.785   0.843   0.487   0.569   0.633   0.196
143   P         0.593   0.466   0.363   0.522   0.354   0.215   0.569   0.364   0.159
144   -        -0.490  -0.546  -0.449  -0.463  -0.568  -0.434  -0.697  -0.773  -0.640
145   E        -0.898  -0.966  -0.894  -0.995  -1.119  -1.005  -0.927  -0.989  -0.877
146   L         0.123   0.139   0.223  -0.059  -0.026   0.102  -0.247  -0.223  -0.102
147   A        -0.072  -0.039  -0.308  -0.039   0.003  -0.383  -0.111  -0.066  -0.446
148   A        -0.898  -0.892  -0.887  -0.961  -0.947  -0.926  -0.927  -0.921  -0.872
149   S        -1.239  -1.214  -1.255  -1.137  -1.098  -1.165  -1.063  -1.031  -1.035
150   K        -0.898  -0.943  -0.876  -0.978  -1.052  -0.962  -0.927  -0.963  -0.860
151   Q         0.123   0.144   0.222  -0.048  -0.025   0.110  -0.247  -0.214  -0.103
152   P        -0.072  -0.023  -0.304  -0.093  -0.030  -0.412  -0.111  -0.043  -0.440
153   G         0.593   0.466   0.363   0.637   0.469   0.310   0.569   0.364   0.159
154   Q         1.298   1.311   1.363   1.385   1.407   1.484   1.385   1.404   1.478
155   K        -0.686  -0.732  -0.836  -0.594  -0.670  -0.844  -0.655  -0.714  -0.812
156   M        -1.239  -1.214  -1.255  -0.976  -0.933  -1.030  -1.063  -1.031  -1.035
157   D        -1.239  -1.195  -1.237  -1.193  -1.132  -1.197  -1.063  -1.020  -1.018
158   L         1.298   1.311   1.363   1.264   1.291   1.369   1.385   1.404   1.478
159   P         0.269   0.374   0.320  -0.008   0.164   0.069   0.025   0.207   0.080
160   V        -0.686  -0.684  -0.833  -0.520  -0.509  -0.773  -0.655  -0.647  -0.808
161   D         0.593   0.597   0.383   0.598   0.610   0.281   0.569   0.575   0.196
162   R         1.298   1.311   1.363   1.338   1.357   1.439   1.385   1.404   1.478
163   T         0.593   0.466   0.363   0.695   0.521   0.332   0.569   0.364   0.159
164   I        -0.898  -0.960  -0.892  -0.825  -0.936  -0.834  -0.927  -0.981  -0.876
165   S         1.298   1.311   1.363   1.207   1.225   1.315   1.385   1.404   1.478
166   S         0.269   0.312   0.270   0.108   0.177   0.101   0.025   0.097  -0.012
167   I         1.298   1.311   1.363   1.400   1.423   1.498   1.385   1.404   1.478
168   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
169   K         0.269   0.374   0.320   0.167   0.347   0.240   0.025   0.207   0.080
170   S         0.593   0.597   0.383   0.612   0.621   0.292   0.569   0.575   0.196
171   P        -0.516  -0.520  -0.433  -0.769  -0.767  -0.640  -0.747  -0.743  -0.619
172   -        -1.086  -1.049  -0.932  -1.285  -1.215  -1.047  -1.114  -1.069  -0.915
173   D        -1.368  -1.352  -1.266  -1.456  -1.424  -1.289  -1.199  -1.177  -1.046
174   S        -0.429  -0.487  -0.405  -0.691  -0.757  -0.624  -0.655  -0.706  -0.587
175   N        -1.027  -1.001  -0.909  -1.075  -1.047  -0.903  -1.063  -1.026  -0.892
176   E         0.123   0.144   0.222  -0.158  -0.121   0.001  -0.247  -0.214  -0.103
177   F        -0.898  -0.930  -0.891  -0.836  -0.855  -0.817  -0.927  -0.944  -0.873
178   W         1.298   1.311   1.363   1.420   1.440   1.517   1.385   1.404   1.478
179   E         1.298   1.311   1.363   1.246   1.267   1.352   1.385   1.404   1.478
180   Y         1.298   1.311   1.363   1.440   1.458   1.536   1.385   1.404   1.478
181   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
182   S         1.298   1.311   1.363   1.207   1.225   1.315   1.385   1.404   1.478
183   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
184   Q         1.298   1.311   1.363   1.385   1.407   1.484   1.385   1.404   1.478
185   Q         1.298   1.311   1.363   1.385   1.407   1.484   1.385   1.404   1.478
186   M         1.298   1.311   1.363   1.403   1.424   1.501   1.385   1.404   1.478
187   Y         0.269   0.374   0.320   0.299   0.479   0.357   0.025   0.207   0.080
188   N         1.298   1.311   1.363   1.353   1.372   1.453   1.385   1.404   1.478
189   A         1.298   1.311   1.363   1.289   1.294   1.393   1.385   1.404   1.478
190   M         0.593   0.466   0.363   0.763   0.590   0.404   0.569   0.364   0.159
191   V        -0.346  -0.316  -0.389  -0.390  -0.338  -0.437  -0.519  -0.475  -0.562
192   R        -0.072   0.094  -0.280   0.060   0.287  -0.277  -0.111   0.115  -0.406
193   K         1.298   1.311   1.363   1.271   1.301   1.376   1.385   1.404   1.478
194   G         1.298   1.311   1.363   1.261   1.281   1.366   1.385   1.404   1.478
195   K         0.523   0.392   0.326   0.571   0.403   0.290   0.460   0.239   0.092
196   I         0.331   0.255   0.270   0.405   0.279   0.277   0.136  -0.005  -0.012
197   G         0.331   0.369   0.301   0.196   0.267   0.128   0.136   0.199   0.045
198   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
199   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
200   G        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
201   S         0.523   0.505   0.335   0.508   0.481   0.194   0.460   0.429   0.107
202   G        -0.989  -0.912  -0.902  -1.121  -1.013  -0.976  -1.021  -0.940  -0.885
203   E         0.203   0.275   0.274  -0.017   0.112   0.090  -0.096   0.032  -0.005
204   V        -0.346  -0.411  -0.382  -0.280  -0.363  -0.346  -0.519  -0.590  -0.554
205   A        -0.072  -0.188  -0.329  -0.131  -0.312  -0.523  -0.111  -0.276  -0.475
206   E         0.593   0.466   0.363   0.629   0.468   0.314   0.569   0.364   0.159
207   D         0.593   0.466   0.363   0.589   0.426   0.265   0.569   0.364   0.159
208   A         1.298   1.311   1.363   1.289   1.294   1.393   1.385   1.404   1.478
209   V         1.298   1.311   1.363   1.320   1.334   1.422   1.385   1.404   1.478
210   E         1.298   1.311   1.363   1.246   1.267   1.352   1.385   1.404   1.478
211   S         1.298   1.311   1.363   1.207   1.225   1.315   1.385   1.404   1.478
212   M         1.298   1.311   1.363   1.403   1.424   1.501   1.385   1.404   1.478
213   V         1.298   1.311   1.363   1.320   1.334   1.422   1.385   1.404   1.478
214   Q        -1.708  -1.693  -1.585  -1.578  -1.557  -1.388  -1.335  -1.314  -1.168
215   V         1.298   1.311   1.363   1.320   1.334   1.422   1.385   1.404   1.478
216   H         1.298   1.311   1.363   1.475   1.495   1.569   1.385   1.404   1.478
217   N         1.298   1.311   1.363   1.353   1.372   1.453   1.385   1.404   1.478
218   F         1.298   1.311   1.363   1.383   1.405   1.482   1.385   1.404   1.478
219   L         1.298   1.311   1.363   1.264   1.291   1.369   1.385   1.404   1.478
220   N         1.298   1.311   1.363   1.353   1.372   1.453   1.385   1.404   1.478
221   E         1.298   1.311   1.363   1.246   1.267   1.352   1.385   1.404   1.478
222   G         1.298   1.311   1.363   1.261   1.281   1.366   1.385   1.404   1.478
223   C         0.123   0.144   0.222   0.029   0.049   0.187  -0.247  -0.214  -0.103
224   W         1.298   1.311   1.363   1.420   1.440   1.517   1.385   1.404   1.478
225   Q        -0.072  -0.195  -0.339   0.145  -0.030  -0.269  -0.111  -0.285  -0.489
226   E         0.269   0.374   0.320   0.161   0.329   0.238   0.025   0.207   0.080
227   V         0.593   0.597   0.383   0.770   0.781   0.457   0.569   0.575   0.196
228   L        -0.072  -0.195  -0.339   0.057  -0.108  -0.307  -0.111  -0.285  -0.489
229   E        -0.429  -0.365  -0.392  -0.642  -0.552  -0.548  -0.655  -0.582  -0.573
230   W         1.298   1.311   1.363   1.420   1.440   1.517   1.385   1.404   1.478
231   E         1.298   1.311   1.363   1.246   1.267   1.352   1.385   1.404   1.478
232   K        -0.686  -0.650  -0.830  -0.568  -0.516  -0.793  -0.655  -0.620  -0.805
233   P        -0.898  -0.915  -0.877  -0.982  -1.007  -0.923  -0.927  -0.942  -0.860
234   H        -0.072  -0.188  -0.329   0.233   0.071  -0.140  -0.111  -0.276  -0.475
235   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
236   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
237   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
238   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
239   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
240   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
241   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
242   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
243   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
244   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
245   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
246   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
247   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
248   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
249   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
250   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
251   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
252   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
253   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
254   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
255   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
256   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
257   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
258   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
259   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
260   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
261   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
262   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
263   T         0.593   0.466   0.363   0.700   0.527   0.344   0.569   0.364   0.159
264   D        -0.898  -0.912  -0.874  -0.959  -0.974  -0.894  -0.927  -0.937  -0.857
265   E        -1.708  -1.677  -1.589  -1.617  -1.579  -1.449  -1.335  -1.303  -1.171
266   S        -0.346  -0.433  -0.396  -0.428  -0.573  -0.548  -0.519  -0.623  -0.571
267   H        -0.898  -0.963  -0.893  -0.869  -0.955  -0.865  -0.927  -0.985  -0.877
268   V        -0.898  -0.921  -0.873  -0.864  -0.917  -0.834  -0.927  -0.939  -0.857
269   Q        -0.346  -0.360  -0.398  -0.367  -0.398  -0.413  -0.519  -0.555  -0.578
270   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
271   K        -0.429  -0.490  -0.415  -0.533  -0.596  -0.483  -0.655  -0.711  -0.600
272   L         1.298   1.311   1.363   1.264   1.291   1.369   1.385   1.404   1.478
273   L        -0.686  -0.732  -0.836  -0.542  -0.596  -0.756  -0.655  -0.714  -0.812
274   K        -0.346  -0.333  -0.386  -0.378  -0.361  -0.426  -0.519  -0.511  -0.561
275   F         1.298   1.311   1.363   1.383   1.405   1.482   1.385   1.404   1.478
276   M        -0.558  -0.561  -0.454  -0.594  -0.593  -0.435  -0.791  -0.793  -0.646
277   G         1.298   1.311   1.363   1.261   1.281   1.366   1.385   1.404   1.478
278   K         0.269   0.293   0.264   0.205   0.248   0.162   0.025   0.064  -0.025
279   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
280   G        -1.368  -1.396  -1.285  -1.267  -1.316  -1.163  -1.199  -1.210  -1.061
281   V        -0.686  -0.648  -0.838  -0.614  -0.553  -0.834  -0.655  -0.606  -0.814
282   L         0.269   0.208   0.234   0.185   0.090   0.120   0.025  -0.092  -0.081
283   S         0.593   0.466   0.363   0.581   0.412   0.258   0.569   0.364   0.159
284   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
285   R         0.269   0.243   0.254   0.205   0.157   0.143   0.025  -0.028  -0.043
286   A         1.298   1.311   1.363   1.289   1.294   1.393   1.385   1.404   1.478
287   R        -0.686  -0.718  -0.843  -0.518  -0.579  -0.783  -0.655  -0.699  -0.819
288   W        -0.898  -0.942  -0.896  -0.710  -0.778  -0.697  -0.927  -0.966  -0.879
289   M        -1.708  -1.723  -1.599  -1.358  -1.393  -1.224  -1.335  -1.335  -1.178
290   H        -1.368  -1.320  -1.273  -1.171  -1.077  -0.998  -1.199  -1.143  -1.051
291   L        -1.368  -1.382  -1.285  -1.232  -1.262  -1.111  -1.199  -1.199  -1.061
292   C        -0.686  -0.648  -0.838  -0.489  -0.426  -0.675  -0.655  -0.606  -0.814
293   G         1.298   1.311   1.363   1.261   1.281   1.366   1.385   1.404   1.478
294   L        -1.239  -1.245  -1.239  -1.091  -1.097  -1.095  -1.063  -1.067  -1.020
295   L        -0.346  -0.367  -0.394  -0.372  -0.398  -0.431  -0.519  -0.550  -0.572
296   F         1.298   1.311   1.363   1.376   1.396   1.475   1.385   1.404   1.478
297   P         0.593   0.466   0.363   0.517   0.345   0.203   0.569   0.364   0.159
298   S        -1.368  -1.295  -1.263  -1.475  -1.370  -1.313  -1.199  -1.126  -1.044
299   H        -0.686  -0.759  -0.850  -0.441  -0.551  -0.674  -0.655  -0.744  -0.827
300   F         0.269   0.218   0.239   0.310   0.225   0.241   0.025  -0.074  -0.071
301   S        -1.368  -1.390  -1.283  -1.308  -1.351  -1.169  -1.199  -1.205  -1.060
302   Q        -0.898  -0.879  -0.885  -0.908  -0.871  -0.887  -0.927  -0.898  -0.869
303   E        -0.686  -0.552  -0.815  -0.560  -0.382  -0.740  -0.655  -0.493  -0.789
304   L        -0.429  -0.422  -0.411  -0.696  -0.683  -0.633  -0.655  -0.639  -0.595
305   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
306   F         1.298   1.311   1.363   1.383   1.405   1.482   1.385   1.404   1.478
307   D         1.298   1.311   1.363   1.215   1.239   1.322   1.385   1.404   1.478
308   R         1.298   1.311   1.363   1.338   1.357   1.439   1.385   1.404   1.478
309   H         1.298   1.311   1.363   1.475   1.495   1.569   1.385   1.404   1.478
310   D         1.298   1.311   1.363   1.215   1.239   1.322   1.385   1.404   1.478
311   W         1.298   1.311   1.363   1.420   1.440   1.517   1.385   1.404   1.478
312   I        -0.898  -0.949  -0.895  -0.772  -0.828  -0.748  -0.927  -0.972  -0.878
313   V         1.298   1.311   1.363   1.320   1.334   1.422   1.385   1.404   1.478
314   L         0.593   0.466   0.363   0.615   0.443   0.258   0.569   0.364   0.159
315   R         1.298   1.311   1.363   1.338   1.357   1.439   1.385   1.404   1.478
316   G        -1.239  -1.296  -1.264  -1.284  -1.395  -1.359  -1.063  -1.115  -1.042
317   E        -1.708  -1.604  -1.572  -1.551  -1.405  -1.352  -1.335  -1.239  -1.158
318   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
319   R        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
320   K        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
321   A        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
322   E        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
323   Q        -0.993  -1.025  -0.926  -1.046  -1.092  -0.946  -1.014  -1.042  -0.909
324   Q        -0.993  -1.025  -0.926  -1.001  -1.052  -0.921  -1.014  -1.042  -0.909
325   P        -0.898  -0.833  -0.867  -0.960  -0.869  -0.910  -0.927  -0.855  -0.849
326   P        -1.368  -1.390  -1.283  -1.390  -1.433  -1.268  -1.199  -1.205  -1.060
327   T        -0.686  -0.792  -0.856  -0.552  -0.702  -0.797  -0.655  -0.780  -0.833
328   F        -0.898  -0.892  -0.887  -0.761  -0.767  -0.743  -0.927  -0.921  -0.872
329   K        -0.686  -0.589  -0.816  -0.561  -0.410  -0.759  -0.655  -0.536  -0.789
330   E        -0.072   0.052  -0.287   0.004   0.172  -0.307  -0.111   0.058  -0.416
331   V         1.298   1.311   1.363   1.320   1.334   1.422   1.385   1.404   1.478
332   R         1.298   1.311   1.363   1.338   1.357   1.439   1.385   1.404   1.478
333   Y         1.298   1.311   1.363   1.440   1.458   1.536   1.385   1.404   1.478
334   V         0.593   0.635   0.383   0.703   0.754   0.413   0.569   0.633   0.196
335   L         0.269   0.284   0.268   0.261   0.289   0.220   0.025   0.047  -0.016
336   D         1.298   1.311   1.363   1.215   1.239   1.322   1.385   1.404   1.478
337   F         0.123   0.168   0.234   0.061   0.139   0.233  -0.247  -0.167  -0.080
338   Y         1.298   1.311   1.363   1.440   1.458   1.536   1.385   1.404   1.478
339   G         0.269   0.208   0.234   0.107  -0.014   0.003   0.025  -0.092  -0.081
340   G         0.123   0.139   0.223  -0.131  -0.115   0.030  -0.247  -0.223  -0.102
341   P         0.593   0.590   0.376   0.493   0.488   0.173   0.569   0.563   0.183
342   D         0.593   0.466   0.363   0.555   0.375   0.189   0.569   0.364   0.159
343   D         0.269   0.208   0.234   0.077  -0.032  -0.012   0.025  -0.092  -0.081
344   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
345   E        -0.072  -0.173  -0.321  -0.041  -0.204  -0.447  -0.111  -0.256  -0.464
346   N        -0.898  -0.874  -0.888  -0.881  -0.841  -0.883  -0.927  -0.894  -0.871
347   G         1.298   1.311   1.363   1.261   1.281   1.366   1.385   1.404   1.478
348   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
349   M        -0.898  -0.960  -0.892  -0.843  -0.934  -0.847  -0.927  -0.981  -0.876
350   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
351   T        -0.346  -0.369  -0.370  -0.351  -0.365  -0.386  -0.519  -0.528  -0.534
352   F         1.298   1.311   1.363   1.383   1.405   1.482   1.385   1.404   1.478
353   H        -1.708  -1.677  -1.589  -1.337  -1.294  -1.164  -1.335  -1.303  -1.171
354   V         0.269   0.284   0.268   0.153   0.181   0.133   0.025   0.047  -0.016
355   D         1.298   1.311   1.363   1.215   1.239   1.322   1.385   1.404   1.478
356   V         0.269   0.374   0.320   0.215   0.381   0.285   0.025   0.207   0.080
357   R         1.298   1.311   1.363   1.338   1.357   1.439   1.385   1.404   1.478
358   P         1.298   1.311   1.363   1.141   1.156   1.253   1.385   1.404   1.478
359   A         1.298   1.311   1.363   1.289   1.294   1.393   1.385   1.404   1.478
360   L         0.593   0.466   0.363   0.634   0.469   0.300   0.569   0.364   0.159
361   D         1.298   1.311   1.363   1.201   1.220   1.310   1.385   1.404   1.478
362   S        -0.429  -0.487  -0.405  -0.568  -0.639  -0.504  -0.655  -0.706  -0.587
363   L        -1.368  -1.378  -1.271  -1.372  -1.377  -1.191  -1.199  -1.197  -1.050
364   D        -0.898  -0.879  -0.885  -0.930  -0.893  -0.928  -0.927  -0.898  -0.869
365   N        -0.072  -0.195  -0.339   0.089  -0.097  -0.342  -0.111  -0.285  -0.489
366   A        -0.072  -0.064  -0.307   0.082   0.079  -0.239  -0.111  -0.099  -0.444
367   K        -1.368  -1.361  -1.274  -1.170  -1.139  -1.002  -1.199  -1.185  -1.052
368   D         0.593   0.466   0.363   0.572   0.402   0.228   0.569   0.364   0.159
369   R         1.298   1.311   1.363   1.338   1.357   1.439   1.385   1.404   1.478
370   M        -0.686  -0.792  -0.856  -0.450  -0.613  -0.730  -0.655  -0.780  -0.833
371   T        -1.239  -1.287  -1.261  -1.074  -1.155  -1.142  -1.063  -1.106  -1.040
372   R        -0.346  -0.272  -0.357  -0.282  -0.163  -0.302  -0.519  -0.401  -0.516
373   F        -0.072  -0.057  -0.308   0.208   0.231  -0.135  -0.111  -0.090  -0.445
374   L        -1.708  -1.693  -1.585  -1.622  -1.608  -1.434  -1.335  -1.314  -1.168
375   D        -1.708  -1.659  -1.580  -1.655  -1.603  -1.463  -1.335  -1.289  -1.164
376   R        -0.686  -0.792  -0.856  -0.731  -0.902  -0.993  -0.655  -0.780  -0.833
377   M        -1.368  -1.387  -1.278  -1.246  -1.255  -1.087  -1.199  -1.203  -1.055
378   I        -0.686  -0.648  -0.838  -0.396  -0.336  -0.643  -0.655  -0.606  -0.814
379   S        -1.708  -1.723  -1.599  -1.624  -1.619  -1.471  -1.335  -1.335  -1.178
380   G        -0.686  -0.598  -0.809  -0.591  -0.457  -0.794  -0.655  -0.548  -0.781
381   P        -0.346  -0.322  -0.388  -0.370  -0.346  -0.447  -0.519  -0.480  -0.560
382   S        -0.442  -0.447  -0.419  -0.484  -0.523  -0.465  -0.651  -0.664  -0.604
383   S        -0.194  -0.205  -0.353  -0.173  -0.192  -0.435  -0.281  -0.295  -0.509
384   S        -0.194  -0.304  -0.365  -0.208  -0.381  -0.506  -0.281  -0.436  -0.524
385   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
386   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
387   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
388   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
389   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
390   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
391   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
392   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
393   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
394   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
395   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
396   -        -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000  -1.000     *
397   S        -1.708  -1.701  -1.582  -1.602  -1.609  -1.448  -1.335  -1.320  -1.166
398   S        -1.027  -1.007  -0.912  -1.159  -1.112  -0.958  -1.063  -1.033  -0.896
399   A        -1.708  -1.723  -1.599  -1.682  -1.714  -1.516  -1.335  -1.335  -1.178
400   P        -0.839  -0.800  -0.852  -0.893  -0.826  -0.949  -0.836  -0.786  -0.829
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P06182
Output conservation file - output/P06182
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
