1     M         0.643   0.650   0.695   1.112   1.106   1.077   0.652   0.661   0.722
2     G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
3     A         0.643   0.650   0.695   0.703   0.718   0.765   0.652   0.661   0.722
4     Y        -0.397  -0.483  -0.954  -0.110  -0.213  -0.946  -0.323  -0.432  -1.112
5     K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
6     Y         0.643   0.650   0.695   0.716   0.725   0.775   0.652   0.661   0.722
7     L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
8     E         0.643   0.650   0.695   0.898   0.900   0.913   0.652   0.661   0.722
9     E         0.643   0.650   0.695   0.898   0.900   0.913   0.652   0.661   0.722
10    L        -0.397  -0.596  -0.958  -0.139  -0.377  -0.881  -0.323  -0.580  -1.118
11    Q        -1.887  -2.081  -1.964  -1.406  -1.675  -1.616  -1.785  -1.994  -1.786
12    R        -1.255  -1.276  -0.991  -2.206  -2.223  -1.638  -1.541  -1.584  -1.170
13    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
14    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
15    Q         0.643   0.650   0.695   0.856   0.860   0.882   0.652   0.661   0.722
16    S         0.643   0.650   0.695   0.767   0.772   0.814   0.652   0.661   0.722
17    D         0.643   0.650   0.695   0.981   0.979   0.977   0.652   0.661   0.722
18    V         0.643   0.650   0.695   0.630   0.639   0.709   0.652   0.661   0.722
19    L        -3.153  -3.123  -2.676  -2.727  -2.729  -2.162  -2.759  -2.701  -2.116
20    R        -0.936  -0.975  -0.965  -1.604  -1.648  -1.482  -1.054  -1.117  -1.129
21    F         0.643   0.650   0.695   1.043   1.041   1.024   0.652   0.661   0.722
22    L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
23    Q        -3.898  -3.750  -3.220  -3.289  -3.185  -2.507  -3.125  -2.989  -2.307
24    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
25    V         0.643   0.650   0.695   0.630   0.639   0.709   0.652   0.661   0.722
26    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
27    V        -2.520  -2.387  -1.966  -2.226  -2.012  -1.596  -2.516  -2.342  -1.789
28    W         0.643   0.650   0.695   0.993   0.991   0.986   0.652   0.661   0.722
29    E         0.643   0.650   0.695   0.898   0.900   0.913   0.652   0.661   0.722
30    Y        -0.397  -0.483  -0.954  -0.110  -0.213  -0.946  -0.323  -0.432  -1.112
31    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
32    Q         0.643   0.650   0.695   0.856   0.860   0.882   0.652   0.661   0.722
33    K        -1.887  -1.989  -1.962  -1.741  -1.851  -1.781  -1.785  -1.897  -1.785
34    N        -0.936  -1.031  -0.986  -0.733  -0.887  -0.894  -1.054  -1.201  -1.162
35    V        -0.397  -0.596  -0.958  -0.196  -0.437  -1.010  -0.323  -0.580  -1.118
36    I         0.643   0.650   0.695   0.898   0.891   0.913   0.652   0.661   0.722
37    H         0.643   0.650   0.695   0.906   0.900   0.920   0.652   0.661   0.722
38    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
39    A         0.643   0.650   0.695   0.703   0.718   0.765   0.652   0.661   0.722
40    A        -0.397  -0.231  -0.948  -0.053   0.119  -0.881  -0.323  -0.123  -1.103
41    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
42    P         0.643   0.650   0.695   0.894   0.890   0.910   0.652   0.661   0.722
43    T        -0.936  -0.722  -0.960  -0.700  -0.425  -0.834  -1.054  -0.752  -1.122
44    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
45    P         0.643   0.650   0.695   0.894   0.890   0.910   0.652   0.661   0.722
46    D         0.643   0.650   0.695   0.981   0.979   0.977   0.652   0.661   0.722
47    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
48    A         0.643   0.650   0.695   0.703   0.718   0.765   0.652   0.661   0.722
49    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
50    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
51    L        -0.397  -0.174  -0.948  -0.111   0.096  -0.772  -0.323  -0.057  -1.103
52    G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
53    Y         0.643   0.650   0.695   0.716   0.725   0.775   0.652   0.661   0.722
54    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
55    A         0.643   0.650   0.695   0.703   0.718   0.765   0.652   0.661   0.722
56    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
57    Q         0.643   0.650   0.695   0.856   0.860   0.882   0.652   0.661   0.722
58    G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
59    F        -1.255  -1.276  -0.991  -0.998  -1.085  -0.796  -1.541  -1.584  -1.170
60    V         0.643   0.650   0.695   0.630   0.639   0.709   0.652   0.661   0.722
61    I         0.643   0.650   0.695   0.898   0.891   0.913   0.652   0.661   0.722
62    Y         0.643   0.650   0.695   0.716   0.725   0.775   0.652   0.661   0.722
63    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
64    V        -2.150  -2.165  -1.970  -1.983  -2.002  -1.736  -2.150  -2.138  -1.794
65    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
66    V         0.643   0.650   0.695   0.630   0.639   0.709   0.652   0.661   0.722
67    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
68    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
69    G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
70    N        -1.405  -1.320  -0.991  -1.607  -1.490  -1.012  -1.785  -1.656  -1.169
71    R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
72    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
73    R        -0.397  -0.483  -0.954  -0.956  -1.034  -1.601  -0.323  -0.432  -1.112
74    P         0.643   0.650   0.695   0.894   0.890   0.910   0.652   0.661   0.722
75    V        -1.395  -1.557  -1.954  -0.992  -1.196  -1.781  -1.176  -1.366  -1.776
76    P        -1.395  -1.432  -1.950  -0.770  -0.866  -1.744  -1.176  -1.233  -1.772
77    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
78    G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
79    A        -0.936  -0.975  -0.965  -0.762  -0.824  -0.882  -1.054  -1.117  -1.129
80    T         0.643   0.650   0.695   0.856   0.863   0.882   0.652   0.661   0.722
81    Y         0.643   0.650   0.695   0.716   0.725   0.775   0.652   0.661   0.722
82    G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
83    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
84    P         0.643   0.650   0.695   0.894   0.890   0.910   0.652   0.661   0.722
85    T        -1.255  -1.246  -0.991  -1.206  -1.224  -0.948  -1.541  -1.535  -1.170
86    N        -0.936  -0.975  -0.965  -0.719  -0.793  -0.840  -1.054  -1.117  -1.129
87    Q        -0.397  -0.369  -0.952   0.061   0.083  -0.744  -0.323  -0.289  -1.110
88    G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
89    V        -0.397  -0.596  -0.958  -0.165  -0.394  -0.897  -0.323  -0.580  -1.118
90    N         0.643   0.650   0.695   0.733   0.737   0.788   0.652   0.661   0.722
91    E        -2.324  -2.150  -1.961  -1.900  -1.696  -1.534  -2.272  -2.070  -1.784
92    L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
93    K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
94    Y        -0.397  -0.596  -0.958  -0.110  -0.351  -0.953  -0.323  -0.580  -1.118
95    Q         0.643   0.650   0.695   0.856   0.860   0.882   0.652   0.661   0.722
96    R        -0.397  -0.224  -0.948  -0.956  -0.736  -1.593  -0.323  -0.115  -1.104
97    S        -0.397  -0.369  -0.952  -0.053  -0.028  -0.889  -0.323  -0.289  -1.110
98    L        -0.936  -0.975  -0.965  -0.851  -0.930  -0.982  -1.054  -1.117  -1.129
99    R        -0.397  -0.483  -0.954  -0.956  -1.034  -1.601  -0.323  -0.432  -1.112
100   A        -2.324  -2.298  -1.971  -2.004  -1.978  -1.596  -2.272  -2.237  -1.795
101   T        -0.397  -0.596  -0.958   0.027  -0.217  -0.875  -0.323  -0.580  -1.118
102   A         0.643   0.650   0.695   0.703   0.718   0.765   0.652   0.661   0.722
103   E         0.643   0.650   0.695   0.898   0.900   0.913   0.652   0.661   0.722
104   E         0.643   0.650   0.695   0.898   0.900   0.913   0.652   0.661   0.722
105   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
106   V         0.643   0.650   0.695   0.630   0.639   0.709   0.652   0.661   0.722
107   G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
108   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
109   R        -0.936  -0.975  -0.965  -1.585  -1.623  -1.451  -1.054  -1.117  -1.129
110   A        -1.255  -1.276  -0.991  -1.122  -1.159  -0.780  -1.541  -1.584  -1.170
111   A        -2.150  -2.213  -1.968  -1.976  -2.041  -1.777  -2.150  -2.170  -1.792
112   N         0.643   0.650   0.695   0.733   0.737   0.788   0.652   0.661   0.722
113   L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
114   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
115   V         0.643   0.650   0.695   0.630   0.639   0.709   0.652   0.661   0.722
116   L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
117   N         0.643   0.650   0.695   0.733   0.737   0.788   0.652   0.661   0.722
118   S         0.643   0.650   0.695   0.767   0.772   0.814   0.652   0.661   0.722
119   Y         0.643   0.650   0.695   0.716   0.725   0.775   0.652   0.661   0.722
120   W         0.643   0.650   0.695   0.993   0.991   0.986   0.652   0.661   0.722
121   V        -0.936  -0.889  -0.981  -0.821  -0.769  -0.928  -1.054  -0.989  -1.154
122   N         0.643   0.650   0.695   0.733   0.737   0.788   0.652   0.661   0.722
123   Q        -0.397  -0.369  -0.952   0.060   0.083  -0.748  -0.323  -0.289  -1.110
124   D         0.643   0.650   0.695   0.981   0.979   0.977   0.652   0.661   0.722
125   S        -0.936  -0.975  -0.965  -0.743  -0.818  -0.912  -1.054  -1.117  -1.129
126   T         0.643   0.650   0.695   0.856   0.863   0.882   0.652   0.661   0.722
127   Y         0.643   0.650   0.695   0.716   0.725   0.775   0.652   0.661   0.722
128   K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
129   Y        -0.936  -0.975  -0.965  -0.697  -0.759  -0.787  -1.054  -1.117  -1.129
130   F         0.643   0.650   0.695   1.043   1.041   1.024   0.652   0.661   0.722
131   E         0.643   0.650   0.695   0.898   0.900   0.913   0.652   0.661   0.722
132   V         0.643   0.650   0.695   0.630   0.639   0.709   0.652   0.661   0.722
133   I         0.643   0.650   0.695   0.898   0.891   0.913   0.652   0.661   0.722
134   L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
135   V        -0.397  -0.369  -0.952  -0.196  -0.168  -0.999  -0.323  -0.289  -1.110
136   D         0.643   0.650   0.695   0.981   0.979   0.977   0.652   0.661   0.722
137   P         0.643   0.650   0.695   0.894   0.890   0.910   0.652   0.661   0.722
138   Q        -0.936  -0.888  -0.981  -0.700  -0.648  -0.866  -1.054  -0.988  -1.154
139   H         0.643   0.650   0.695   0.906   0.900   0.920   0.652   0.661   0.722
140   K        -0.397  -0.596  -0.958  -0.424  -0.638  -1.165  -0.323  -0.580  -1.118
141   A        -0.397  -0.596  -0.958  -0.126  -0.361  -0.973  -0.323  -0.580  -1.118
142   I         0.643   0.650   0.695   0.898   0.891   0.913   0.652   0.661   0.722
143   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
144   R        -0.397  -0.596  -0.958  -0.910  -1.118  -1.436  -0.323  -0.580  -1.118
145   D         0.643   0.650   0.695   0.981   0.979   0.977   0.652   0.661   0.722
146   A        -1.405  -1.353  -0.990  -1.462  -1.377  -0.886  -1.785  -1.709  -1.168
147   R        -0.397  -0.232  -0.948  -0.956  -0.744  -1.593  -0.323  -0.124  -1.104
148   Y        -1.405  -1.353  -0.990  -1.450  -1.371  -0.877  -1.785  -1.709  -1.168
149   N         0.643   0.650   0.695   0.733   0.737   0.788   0.652   0.661   0.722
150   W         0.643   0.650   0.695   0.993   0.991   0.986   0.652   0.661   0.722
151   I         0.643   0.650   0.695   0.898   0.891   0.913   0.652   0.661   0.722
152   C        -2.234  -2.149  -1.970  -1.930  -1.852  -1.629  -2.272  -2.159  -1.794
153   D        -0.397  -0.231  -0.948  -0.052   0.111  -0.782  -0.323  -0.123  -1.103
154   P         0.643   0.650   0.695   0.894   0.890   0.910   0.652   0.661   0.722
155   V         0.643   0.650   0.695   0.630   0.639   0.709   0.652   0.661   0.722
156   H         0.643   0.650   0.695   0.906   0.900   0.920   0.652   0.661   0.722
157   K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
158   H         0.643   0.650   0.695   0.906   0.900   0.920   0.652   0.661   0.722
159   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
160   E         0.643   0.650   0.695   0.898   0.900   0.913   0.652   0.661   0.722
161   A        -1.405  -1.353  -0.990  -1.544  -1.468  -0.959  -1.785  -1.709  -1.168
162   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
163   G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
164   L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
165   T         0.643   0.650   0.695   0.856   0.863   0.882   0.652   0.661   0.722
166   A        -1.405  -1.320  -0.991  -1.534  -1.404  -0.961  -1.785  -1.656  -1.169
167   T        -2.324  -2.348  -1.971  -1.971  -2.043  -1.638  -2.272  -2.296  -1.795
168   G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
169   K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
170   K        -0.397  -0.483  -0.954  -0.514  -0.605  -1.494  -0.323  -0.432  -1.112
171   S        -0.397  -0.596  -0.958  -0.049  -0.290  -0.886  -0.323  -0.580  -1.118
172   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
173   G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
174   I        -0.397  -0.483  -0.954   0.072  -0.048  -0.829  -0.323  -0.432  -1.112
175   N        -0.936  -0.975  -0.965  -0.790  -0.871  -0.957  -1.054  -1.117  -1.129
176   K         0.643   0.650   0.695   0.405   0.441   0.539   0.652   0.661   0.722
177   G         0.643   0.650   0.695   0.651   0.655   0.726   0.652   0.661   0.722
178   H         0.643   0.650   0.695   0.906   0.900   0.920   0.652   0.661   0.722
179   K        -2.520  -2.383  -1.976  -3.369  -3.165  -2.389  -2.516  -2.352  -1.799
180   F        -1.405  -1.360  -0.993  -1.306  -1.280  -0.811  -1.785  -1.720  -1.173
181   N        -1.887  -1.717  -1.960  -1.466  -1.317  -1.612  -1.785  -1.627  -1.783
182   N        -0.936  -0.885  -0.979  -0.857  -0.792  -1.103  -1.054  -0.983  -1.151
183   T        -0.936  -0.975  -0.965  -0.639  -0.713  -0.828  -1.054  -1.117  -1.129
184   K        -3.612  -3.662  -3.221  -3.358  -3.462  -2.913  -2.881  -2.904  -2.307
185   A         0.643   0.650   0.695   0.693   0.712   0.758   0.652   0.661   0.722
186   G         0.643   0.650   0.695   0.660   0.661   0.732   0.652   0.661   0.722
187   R        -0.936  -0.975  -0.965  -1.540  -1.573  -1.376  -1.054  -1.117  -1.129
188   R        -0.936  -0.975  -0.965  -1.524  -1.558  -1.350  -1.054  -1.117  -1.129
189   K        -2.520  -2.483  -1.973  -2.614  -2.540  -1.836  -2.516  -2.459  -1.797
190   T         0.643   0.650   0.695   0.856   0.863   0.882   0.652   0.661   0.722
191   W         0.643   0.650   0.695   0.993   0.991   0.986   0.652   0.661   0.722
192   K        -0.936  -0.975  -0.965  -1.111  -1.159  -1.164  -1.054  -1.117  -1.129
193   R        -1.395  -1.425  -1.950  -1.787  -1.812  -2.382  -1.176  -1.226  -1.772
194   Q        -2.150  -2.076  -1.966  -1.763  -1.689  -1.600  -2.150  -2.053  -1.790
195   N         0.643   0.650   0.695   0.733   0.737   0.788   0.652   0.661   0.722
196   T         0.643   0.650   0.695   0.856   0.863   0.882   0.652   0.661   0.722
197   L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
198   S         0.643   0.650   0.695   0.767   0.772   0.814   0.652   0.661   0.722
199   L         0.643   0.650   0.695   0.656   0.656   0.729   0.652   0.661   0.722
200   W        -0.936  -0.975  -0.965  -0.726  -0.834  -1.117  -1.054  -1.117  -1.129
201   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
202   Y         0.643   0.650   0.695   0.716   0.725   0.775   0.652   0.661   0.722
203   R         0.643   0.650   0.695  -0.090  -0.054   0.162   0.652   0.661   0.722
204   K        -1.363  -1.353  -0.994  -1.730  -1.702  -1.126  -1.716  -1.709  -1.174
* gap fraction no less than  0.50; conservation set to M-S
  M: mean;  S: standard deviation

al2co - The parameters are:

Input alignment file - ../mafft-mac/clustal/P05748
Output conservation file - output/P05748
All 9 methods are used - true 
   1. unweighted entropy measure; 2. Henikoff entropy measure;
   3. independent count entropy measure;
   4. unweighted variance measure; 5. Henikoff variance measure;
   6. independent count variance measure;
   7. unweighted matrix-based sum-of-pairs measure;
   8. Henikoff matrix-based sum-of-pairs measure;
   9. independent count matrix-based sum-of-pairs measure;
Window size - 1
Conservation normalized to zero mean and unity variance
Gap fraction to suppress calculation -  0.50
